CA2388272A1 - Electrochemical test strip for use in analyte determination - Google Patents
Electrochemical test strip for use in analyte determination Download PDFInfo
- Publication number
- CA2388272A1 CA2388272A1 CA002388272A CA2388272A CA2388272A1 CA 2388272 A1 CA2388272 A1 CA 2388272A1 CA 002388272 A CA002388272 A CA 002388272A CA 2388272 A CA2388272 A CA 2388272A CA 2388272 A1 CA2388272 A1 CA 2388272A1
- Authority
- CA
- Canada
- Prior art keywords
- test strip
- electrochemical test
- reaction zone
- reagent system
- electrodes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
Abstract
Electrochemical test strips and methods for their use in the detection of an analyte in a physiological sample are provided. The subject test strips have a reaction zone defined by opposing metal electrodes separated by a thin space r layer. The metal surface of at least one of the electrodes is modified by a homogenous surface modification layer made up of linear self-assembling molecules having a first sulfhydryl end group and a second sulfonate end gro up separated by a short chain alkyl linking group, where 2-mercaptoethane sulfonic acid or a salt thereof is preferred in certain embodiments. The subject electrochemical test strips find application in the detection of a wide variety of analytes, and are particularly suited for use the detection of glucose.
Claims (25)
1. An electrochemical test strip comprising:
(a) a reaction zone defined by opposing working and reference electrodes separated by a spacer layer, wherein at least one of said first and second electrodes has a surface modified with a homogenous surface modification layer made up of self assembling molecules having a first sulfhydryl end group and a second sulfonate end group, wherein said sulfhydryl and sulfonate end groups are separated by a lower alkyl linker group; and (b) a redox reagent system present in said reaction zone, wherein said redox reagent system comprises at least one enzyme and a mediator.
(a) a reaction zone defined by opposing working and reference electrodes separated by a spacer layer, wherein at least one of said first and second electrodes has a surface modified with a homogenous surface modification layer made up of self assembling molecules having a first sulfhydryl end group and a second sulfonate end group, wherein said sulfhydryl and sulfonate end groups are separated by a lower alkyl linker group; and (b) a redox reagent system present in said reaction zone, wherein said redox reagent system comprises at least one enzyme and a mediator.
2. The electrochemical test strip according to Claim 1, wherein at least one of said electrodes comprises a metal selected from the group consisting o~ gold, palladium, silver, iridium, carbon, doped indium tin oxide and stainless steel.
3. The electrochemical test strip according to Claim 2, wherein said electrode comprises gold or palladium.
4. The electrochemical test strip according to Claim 1, wherein said self assembling molecules have the formula:
HS-(CH2)n-SO3Y
wherein:
n is an integer from 1 to 6; and Y is H or a cation.
HS-(CH2)n-SO3Y
wherein:
n is an integer from 1 to 6; and Y is H or a cation.
5. The electrochemical test strip according to Claim 1, wherein said at least one enzyme includes an oxidizing enzyme.
6. An electrochemical test strip comprising:
(a) a reaction zone defined by opposing working and reference electrodes comprising a metal surface separated by a thin spacer layer, wherein at least one of said first and second metallic electrodes has a surface modified with a homogenous surface modification layer made up of self assembling molecules of the formula:
HS-(CH2)n-SO3Y
wherein:
n is an integer from 1 to 6; and Y is H or a cation; and (b) a redox reagent system present in said reaction zone, wherein said redox reagent system comprises enzymes and a mediator.
(a) a reaction zone defined by opposing working and reference electrodes comprising a metal surface separated by a thin spacer layer, wherein at least one of said first and second metallic electrodes has a surface modified with a homogenous surface modification layer made up of self assembling molecules of the formula:
HS-(CH2)n-SO3Y
wherein:
n is an integer from 1 to 6; and Y is H or a cation; and (b) a redox reagent system present in said reaction zone, wherein said redox reagent system comprises enzymes and a mediator.
7. The electrochemical test strip according to Claim 6, wherein said reaction zone has a volume ranging from about 0.1 to 10 µl.
8. The elctrochemical test strip according to Claim 6, wherein said metal is selected from the group consisting of gold and palladium.
9. The electrochemical test strip according to Claim 6, wherein said enzymes include an oxidizing enzyme.
10. The electrochemical test strip according to Claim 9, wherein said oxidizing enzyme in a glucose oxidizing enzyme.
11. The electrochemical test strip according to Claim 6, wherein said self assembling molecule is 2-mercaptoethane sulfonic acid or a salt thereof.
12. An electrochemical test strip for use in detecting the concentration of glucose in a physiological sample, said test strip comprising:
(a) a reaction zone defined by opposing working and reference electrodes comprising a metal surface selected from the group consisting of gold and palladium separated by a thin spacer layer, wherein at least one of said first and second metallic electrodes has a surface modified with a homogenous surface modification layer made up of 2-mercaptoethane sulfonic acid or a salt thereof; and (b) a redox reagent system present in said reaction zone, wherein said redox reagent system comprises a glucose oxidizing enzyme and a mediator.
(a) a reaction zone defined by opposing working and reference electrodes comprising a metal surface selected from the group consisting of gold and palladium separated by a thin spacer layer, wherein at least one of said first and second metallic electrodes has a surface modified with a homogenous surface modification layer made up of 2-mercaptoethane sulfonic acid or a salt thereof; and (b) a redox reagent system present in said reaction zone, wherein said redox reagent system comprises a glucose oxidizing enzyme and a mediator.
13. The electrochemical test strip according to Claim 12, wherein said reaction zone has a volume ranging from about 0.1 to 10 µl.
14. The electrochemical test strip according to Claim 12, wherein said reference electrode is a gold electrode.
15. The electrochemical test strip according to Claim 12, wherein said working electrode is a palladium electrode.
16. A method of determining the concentration of an analyte in a physiological sample, said method comprising:
(a) applying said physiological sample to an electrochemical test strip comprising:
(i) a reaction zone defined by opposing working and reference metallic electrodes separated by a spacer layer, wherein at least one of said first and second metallic electrodes has a surface modified with a homogenous surface modification layer made up of self assembling molecules having a first sulfhydryl end group and a second sulfonate end group, wherein said sulfhydryl and sulfonate end groups are separated by a lower alkyl linker group; and (ii) a redox reagent system present in said reaction zone, wherein said redox reagent system comprises at least one enzyme and a mediator;
(b) detecting an electrical signal in said reaction zone using said metallic electrodes; and (c) relating said detected electrical signal to the amount of said analyte in said sample.
(a) applying said physiological sample to an electrochemical test strip comprising:
(i) a reaction zone defined by opposing working and reference metallic electrodes separated by a spacer layer, wherein at least one of said first and second metallic electrodes has a surface modified with a homogenous surface modification layer made up of self assembling molecules having a first sulfhydryl end group and a second sulfonate end group, wherein said sulfhydryl and sulfonate end groups are separated by a lower alkyl linker group; and (ii) a redox reagent system present in said reaction zone, wherein said redox reagent system comprises at least one enzyme and a mediator;
(b) detecting an electrical signal in said reaction zone using said metallic electrodes; and (c) relating said detected electrical signal to the amount of said analyte in said sample.
17 17. The method according to Claim 16, wherein said self assembling molecules have the formula:
HS-(CH2)n-SO3Y
wherein:
n is an integer from 1 to 6; and Y is H or a cation.
HS-(CH2)n-SO3Y
wherein:
n is an integer from 1 to 6; and Y is H or a cation.
18. The method according to Claim 17, wherein said self assembling molecules are 2-mercaptoethane sulfonic acid or a salt thereof.
19. The method according to Claim 16, wherein said analyte is glucose.
20. The method according to Claim 19, wherein said redox reagent system comprises a glucose oxidizing enzyme.
21. A kit for use in determining the concentration of an analyte in a physiological sample, said kit comprising:
(a) an electrochemical test strip comprising:
(i) a reaction zone defined by opposing working and reference metallic electrodes separated by a spacer layer, wherein at least one of said first and second metallic electrodes has a surface modified with a homogenous surface modification layer made up of self assembling molecules having a first sulfhydryl end group and a second sulfonate end group, wherein said sulfhydryl and sulfonate end groups are separated by a lower alkyl linker group; and (ii) a redox reagent system present in said reaction zone, wherein said redox reagent system comprises at least one enzyme and a mediator;
and (b) at least one of:
(i) a means for obtaining said physiological sample; and (ii) an analyte standard.
(a) an electrochemical test strip comprising:
(i) a reaction zone defined by opposing working and reference metallic electrodes separated by a spacer layer, wherein at least one of said first and second metallic electrodes has a surface modified with a homogenous surface modification layer made up of self assembling molecules having a first sulfhydryl end group and a second sulfonate end group, wherein said sulfhydryl and sulfonate end groups are separated by a lower alkyl linker group; and (ii) a redox reagent system present in said reaction zone, wherein said redox reagent system comprises at least one enzyme and a mediator;
and (b) at least one of:
(i) a means for obtaining said physiological sample; and (ii) an analyte standard.
22. The kit according to Claim 21, wherein said analyte is glucose.
23. The kit according to Claim i 21, wherein said physiological sample is blood.
24. The kit according to Claim 21, wherein said means for obtaining said physiological sample is a lance.
25. The kit according to Claim 21, wherein said kit further comprises an automated instrument for detecting an electrical signal using said electrodes and relating said detected signal to the amount of analyte in a sample.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/497,269 | 2000-02-02 | ||
US09/497,269 US6716577B1 (en) | 2000-02-02 | 2000-02-02 | Electrochemical test strip for use in analyte determination |
PCT/US2001/002510 WO2001057238A2 (en) | 2000-02-02 | 2001-01-25 | Electrochemical test strip for use in analyte determination |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2388272A1 true CA2388272A1 (en) | 2001-08-09 |
CA2388272C CA2388272C (en) | 2011-05-10 |
Family
ID=23976142
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2388272A Expired - Lifetime CA2388272C (en) | 2000-02-02 | 2001-01-25 | Electrochemical test strip for use in analyte determination |
Country Status (20)
Country | Link |
---|---|
US (2) | US6716577B1 (en) |
EP (1) | EP1254365B1 (en) |
JP (1) | JP4070999B2 (en) |
KR (1) | KR100856342B1 (en) |
CN (1) | CN1394278A (en) |
AR (1) | AR027347A1 (en) |
AT (1) | ATE449961T1 (en) |
AU (2) | AU778966C (en) |
CA (1) | CA2388272C (en) |
CZ (1) | CZ20022946A3 (en) |
DE (1) | DE60140600D1 (en) |
ES (1) | ES2334883T3 (en) |
HK (1) | HK1050047B (en) |
IL (1) | IL149661A0 (en) |
MX (1) | MXPA02005796A (en) |
MY (1) | MY133963A (en) |
PL (1) | PL358134A1 (en) |
RU (1) | RU2256171C2 (en) |
TW (1) | TW593680B (en) |
WO (1) | WO2001057238A2 (en) |
Families Citing this family (163)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
US20050103624A1 (en) | 1999-10-04 | 2005-05-19 | Bhullar Raghbir S. | Biosensor and method of making |
EP1152239A4 (en) | 1999-11-15 | 2009-05-27 | Panasonic Corp | Biosensor, method of forming thin-film electrode, and method and apparatus for quantitative determination |
US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
EP1397068A2 (en) | 2001-04-02 | 2004-03-17 | Therasense, Inc. | Blood glucose tracking apparatus and methods |
WO2002100254A2 (en) | 2001-06-12 | 2002-12-19 | Pelikan Technologies, Inc. | Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge |
US7025774B2 (en) | 2001-06-12 | 2006-04-11 | Pelikan Technologies, Inc. | Tissue penetration device |
US7981056B2 (en) | 2002-04-19 | 2011-07-19 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US8337419B2 (en) | 2002-04-19 | 2012-12-25 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
ES2352998T3 (en) | 2001-06-12 | 2011-02-24 | Pelikan Technologies Inc. | LANCETA ELECTRIC ACTUATOR. |
CA2448902C (en) | 2001-06-12 | 2010-09-07 | Pelikan Technologies, Inc. | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties |
US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
US20030036202A1 (en) | 2001-08-01 | 2003-02-20 | Maria Teodorcyzk | Methods and devices for use in analyte concentration determination assays |
US20030028125A1 (en) | 2001-08-06 | 2003-02-06 | Yuzhakov Vadim V. | Physiological sample collection devices and methods of using the same |
US6872299B2 (en) * | 2001-12-10 | 2005-03-29 | Lifescan, Inc. | Passive sample detection to initiate timing of an assay |
US6946067B2 (en) | 2002-01-04 | 2005-09-20 | Lifescan, Inc. | Method of forming an electrical connection between an electrochemical cell and a meter |
US6872358B2 (en) | 2002-01-16 | 2005-03-29 | Lifescan, Inc. | Test strip dispenser |
US20030186446A1 (en) | 2002-04-02 | 2003-10-02 | Jerry Pugh | Test strip containers and methods of using the same |
US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7232451B2 (en) * | 2002-04-19 | 2007-06-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7909778B2 (en) | 2002-04-19 | 2011-03-22 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7713214B2 (en) | 2002-04-19 | 2010-05-11 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing |
US7491178B2 (en) | 2002-04-19 | 2009-02-17 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8372016B2 (en) | 2002-04-19 | 2013-02-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling and analyte sensing |
US7976476B2 (en) | 2002-04-19 | 2011-07-12 | Pelikan Technologies, Inc. | Device and method for variable speed lancet |
US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
US7229458B2 (en) | 2002-04-19 | 2007-06-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7547287B2 (en) | 2002-04-19 | 2009-06-16 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7297122B2 (en) | 2002-04-19 | 2007-11-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7175642B2 (en) | 2002-04-19 | 2007-02-13 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
US7901362B2 (en) | 2002-04-19 | 2011-03-08 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8267870B2 (en) | 2002-04-19 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling with hybrid actuation |
US8221334B2 (en) | 2002-04-19 | 2012-07-17 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7892183B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
US8360992B2 (en) | 2002-04-19 | 2013-01-29 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
US7331931B2 (en) | 2002-04-19 | 2008-02-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7674232B2 (en) | 2002-04-19 | 2010-03-09 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7343188B2 (en) * | 2002-05-09 | 2008-03-11 | Lifescan, Inc. | Devices and methods for accessing and analyzing physiological fluid |
US7291256B2 (en) | 2002-09-12 | 2007-11-06 | Lifescan, Inc. | Mediator stabilized reagent compositions and methods for their use in electrochemical analyte detection assays |
US20050049522A1 (en) * | 2002-10-30 | 2005-03-03 | Allen John J | Method of lancing skin for the extraction of blood |
US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
US8771183B2 (en) | 2004-02-17 | 2014-07-08 | Abbott Diabetes Care Inc. | Method and system for providing data communication in continuous glucose monitoring and management system |
AU2003303597A1 (en) | 2002-12-31 | 2004-07-29 | Therasense, Inc. | Continuous glucose monitoring system and methods of use |
US20040193202A1 (en) * | 2003-03-28 | 2004-09-30 | Allen John J. | Integrated lance and strip for analyte measurement |
US20040193072A1 (en) * | 2003-03-28 | 2004-09-30 | Allen John J. | Method of analyte measurement using integrated lance and strip |
US7473264B2 (en) * | 2003-03-28 | 2009-01-06 | Lifescan, Inc. | Integrated lance and strip for analyte measurement |
EP2238892A3 (en) | 2003-05-30 | 2011-02-09 | Pelikan Technologies Inc. | Apparatus for body fluid sampling |
US7850621B2 (en) | 2003-06-06 | 2010-12-14 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
US8066639B2 (en) | 2003-06-10 | 2011-11-29 | Abbott Diabetes Care Inc. | Glucose measuring device for use in personal area network |
WO2006001797A1 (en) | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
US8148164B2 (en) | 2003-06-20 | 2012-04-03 | Roche Diagnostics Operations, Inc. | System and method for determining the concentration of an analyte in a sample fluid |
US7452457B2 (en) | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
US8071030B2 (en) | 2003-06-20 | 2011-12-06 | Roche Diagnostics Operations, Inc. | Test strip with flared sample receiving chamber |
CN1846131B (en) | 2003-06-20 | 2012-01-18 | 霍夫曼-拉罗奇有限公司 | Method and reagent for producing narrow, homogenous reagent strips |
US7220034B2 (en) * | 2003-07-11 | 2007-05-22 | Rudolph Technologies, Inc. | Fiber optic darkfield ring light |
WO2005033659A2 (en) | 2003-09-29 | 2005-04-14 | Pelikan Technologies, Inc. | Method and apparatus for an improved sample capture device |
US20050067277A1 (en) * | 2003-09-30 | 2005-03-31 | Pierce Robin D. | Low volume electrochemical biosensor |
WO2005037095A1 (en) | 2003-10-14 | 2005-04-28 | Pelikan Technologies, Inc. | Method and apparatus for a variable user interface |
US7822454B1 (en) | 2005-01-03 | 2010-10-26 | Pelikan Technologies, Inc. | Fluid sampling device with improved analyte detecting member configuration |
US8668656B2 (en) | 2003-12-31 | 2014-03-11 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for improving fluidic flow and sample capture |
US20050187525A1 (en) * | 2004-02-19 | 2005-08-25 | Hilgers Michael E. | Devices and methods for extracting bodily fluid |
EP1751546A2 (en) | 2004-05-20 | 2007-02-14 | Albatros Technologies GmbH & Co. KG | Printable hydrogel for biosensors |
WO2005120365A1 (en) | 2004-06-03 | 2005-12-22 | Pelikan Technologies, Inc. | Method and apparatus for a fluid sampling device |
US9775553B2 (en) | 2004-06-03 | 2017-10-03 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US7569126B2 (en) | 2004-06-18 | 2009-08-04 | Roche Diagnostics Operations, Inc. | System and method for quality assurance of a biosensor test strip |
US20050284757A1 (en) * | 2004-06-29 | 2005-12-29 | Allen John J | Analyte measuring system which prevents the reuse of a test strip |
US20050284773A1 (en) * | 2004-06-29 | 2005-12-29 | Allen John J | Method of preventing reuse in an analyte measuring system |
US20060000710A1 (en) | 2004-06-30 | 2006-01-05 | Klaus Peter Weidenhaupt | Fluid handling methods |
US8652831B2 (en) | 2004-12-30 | 2014-02-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte measurement test time |
US20060246214A1 (en) * | 2005-04-28 | 2006-11-02 | Plotkin Elliot V | Method for manufacturing an electrochemical-based analytical test strip with hydrophilicity enhanced metal electrodes |
US20060243591A1 (en) * | 2005-04-28 | 2006-11-02 | Plotkin Elliot V | Electrochemical-based analytical test strip with hydrophilicity enhanced metal electrodes |
US8016154B2 (en) * | 2005-05-25 | 2011-09-13 | Lifescan, Inc. | Sensor dispenser device and method of use |
US8192599B2 (en) * | 2005-05-25 | 2012-06-05 | Universal Biosensors Pty Ltd | Method and apparatus for electrochemical analysis |
US8323464B2 (en) * | 2005-05-25 | 2012-12-04 | Universal Biosensors Pty Ltd | Method and apparatus for electrochemical analysis |
US7749371B2 (en) * | 2005-09-30 | 2010-07-06 | Lifescan, Inc. | Method and apparatus for rapid electrochemical analysis |
JP2007121060A (en) * | 2005-10-27 | 2007-05-17 | Sumitomo Electric Ind Ltd | Sensor chip and sensor system |
US7766829B2 (en) | 2005-11-04 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing basal profile modification in analyte monitoring and management systems |
CN100412538C (en) * | 2005-11-10 | 2008-08-20 | 上海师范大学 | A test bar and its preparing process, and method for synchronous detecting rutin and vitamin C in medicine with the same testing bar |
US7620438B2 (en) | 2006-03-31 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and system for powering an electronic device |
US8226891B2 (en) | 2006-03-31 | 2012-07-24 | Abbott Diabetes Care Inc. | Analyte monitoring devices and methods therefor |
US20080124693A1 (en) * | 2006-10-26 | 2008-05-29 | Mcevoy Mary | System for determining an analyte in a bodily fluid sample that includes a graphics-based step-by-step tutorial module |
US8930203B2 (en) | 2007-02-18 | 2015-01-06 | Abbott Diabetes Care Inc. | Multi-function analyte test device and methods therefor |
US8123686B2 (en) | 2007-03-01 | 2012-02-28 | Abbott Diabetes Care Inc. | Method and apparatus for providing rolling data in communication systems |
CN101303347B (en) * | 2007-04-20 | 2013-07-31 | 天津亿朋医疗器械有限公司 | Biological sensor |
US8456301B2 (en) | 2007-05-08 | 2013-06-04 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
US8461985B2 (en) | 2007-05-08 | 2013-06-11 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
US8665091B2 (en) | 2007-05-08 | 2014-03-04 | Abbott Diabetes Care Inc. | Method and device for determining elapsed sensor life |
US7928850B2 (en) | 2007-05-08 | 2011-04-19 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
US7943022B2 (en) | 2007-09-04 | 2011-05-17 | Lifescan, Inc. | Analyte test strip with improved reagent deposition |
US8001825B2 (en) * | 2007-11-30 | 2011-08-23 | Lifescan, Inc. | Auto-calibrating metering system and method of use |
USD612279S1 (en) | 2008-01-18 | 2010-03-23 | Lifescan Scotland Limited | User interface in an analyte meter |
IL197532A0 (en) * | 2008-03-21 | 2009-12-24 | Lifescan Scotland Ltd | Analyte testing method and system |
US9386944B2 (en) | 2008-04-11 | 2016-07-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte detecting device |
USD611151S1 (en) | 2008-06-10 | 2010-03-02 | Lifescan Scotland, Ltd. | Test meter |
USD611372S1 (en) | 2008-09-19 | 2010-03-09 | Lifescan Scotland Limited | Analyte test meter |
US8103456B2 (en) | 2009-01-29 | 2012-01-24 | Abbott Diabetes Care Inc. | Method and device for early signal attenuation detection using blood glucose measurements |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
SG10201400971TA (en) * | 2009-04-17 | 2014-07-30 | Universal Biosensors Pty Ltd | On-board control detection |
WO2010127050A1 (en) | 2009-04-28 | 2010-11-04 | Abbott Diabetes Care Inc. | Error detection in critical repeating data in a wireless sensor system |
US20100300897A1 (en) | 2009-05-28 | 2010-12-02 | Lifescan, Inc. | Flexible indwelling electrochemical-based biosensor and related methods |
US9184490B2 (en) | 2009-05-29 | 2015-11-10 | Abbott Diabetes Care Inc. | Medical device antenna systems having external antenna configurations |
US8173008B2 (en) | 2009-06-24 | 2012-05-08 | Lifescan, Inc. | Method for determining an analyte in a bodily fluid sample using an analyte test strip with combination electrode contact and meter identification feature |
BRPI1015133A2 (en) * | 2009-06-30 | 2016-04-19 | Lifescan Scotland Ltd | diabetes management systems and methods |
EP3973855A1 (en) * | 2009-06-30 | 2022-03-30 | Lifescan, Inc. | Analyte testing methods and device for calculating basal insulin therapy |
US20100332445A1 (en) * | 2009-06-30 | 2010-12-30 | Lifescan, Inc. | Analyte testing method and system |
US8337423B2 (en) * | 2009-07-14 | 2012-12-25 | Becton, Dickinson And Company | Blood glucose sensor |
US8337422B2 (en) * | 2009-07-14 | 2012-12-25 | Becton, Dickinson And Company | Diagnostic test strip having fluid transport features |
WO2011026147A1 (en) | 2009-08-31 | 2011-03-03 | Abbott Diabetes Care Inc. | Analyte signal processing device and methods |
EP2473099A4 (en) | 2009-08-31 | 2015-01-14 | Abbott Diabetes Care Inc | Analyte monitoring system and methods for managing power and noise |
CA3077994C (en) * | 2009-09-29 | 2022-06-21 | Lifescan Scotland Limited | Analyte testing method and device for diabetes management |
US9320461B2 (en) | 2009-09-29 | 2016-04-26 | Abbott Diabetes Care Inc. | Method and apparatus for providing notification function in analyte monitoring systems |
US8956309B2 (en) * | 2010-01-19 | 2015-02-17 | Becton, Dickinson And Company | Sensor strip positioning mechanism |
US8771202B2 (en) * | 2010-01-19 | 2014-07-08 | Becton Dickinson And Company | Electrode layout for blood test sensor strip |
US8844725B2 (en) * | 2010-01-20 | 2014-09-30 | Roche Diagnostics Operations, Inc. | Test strip container with strip retainer and methods of manufacturing and utilization thereof |
US8773106B2 (en) | 2010-02-25 | 2014-07-08 | Lifescan Scotland Limited | Capacitance detection in electrochemical assay with improved sampling time offset |
US8742773B2 (en) | 2010-02-25 | 2014-06-03 | Lifescan Scotland Limited | Capacitance detection in electrochemical assay with improved response |
ES2456899T3 (en) | 2010-02-25 | 2014-04-23 | Lifescan Scotland Limited | Capacitance detection in electrochemical test |
CN102770868B (en) | 2010-02-25 | 2017-02-22 | 生命扫描苏格兰有限公司 | Analyte testing method and system with high and low blood glucose trends notification |
CA2790912A1 (en) | 2010-02-25 | 2011-09-01 | Lifescan Scotland Limited | Analyte testing method and system with safety warnings for insulin dosing |
US20110208435A1 (en) | 2010-02-25 | 2011-08-25 | Lifescan Scotland Ltd. | Capacitance detection in electrochemical assays |
US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US8394343B2 (en) | 2010-04-27 | 2013-03-12 | Roche Diagnostics Operations, Inc. | Integrated test strip container with retaining insert |
US20110278321A1 (en) | 2010-05-11 | 2011-11-17 | Roche Diagnostics Operations, Inc. | Hermetically sealed test strip container |
CN103025242B (en) | 2010-06-30 | 2015-12-09 | 生命扫描苏格兰有限公司 | Guarantee about average before the meal with the mthods, systems and devices of the statistical power of GLPP difference Message Transmission |
US8349612B2 (en) | 2010-11-15 | 2013-01-08 | Roche Diagnostics Operations, Inc. | Guided structured testing kit |
US20130229288A1 (en) | 2010-11-15 | 2013-09-05 | Lifescan Scotland Limited | Server-side initiated communication with analyte meter-side completed data transfer |
AU2012335830B2 (en) | 2011-11-07 | 2017-05-04 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods |
US9903830B2 (en) | 2011-12-29 | 2018-02-27 | Lifescan Scotland Limited | Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte |
ES2656497T3 (en) | 2012-03-30 | 2018-02-27 | Lifescan Scotland Limited | Method of detecting battery and storage status and system in medical control |
JP6246211B2 (en) | 2012-09-07 | 2017-12-13 | シラグ・ゲーエムベーハー・インターナショナルCilag GMBH International | Electrochemical sensors and methods for their manufacture |
US9968306B2 (en) | 2012-09-17 | 2018-05-15 | Abbott Diabetes Care Inc. | Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems |
US9080196B2 (en) | 2012-09-28 | 2015-07-14 | Cilag Gmbh International | System and method for determining hematocrit insensitive glucose concentration |
US9005426B2 (en) | 2012-09-28 | 2015-04-14 | Cilag Gmbh International | System and method for determining hematocrit insensitive glucose concentration |
US9121050B2 (en) | 2013-03-15 | 2015-09-01 | American Sterilizer Company | Non-enzyme based detection method for electronic monitoring of biological indicator |
US8858884B2 (en) | 2013-03-15 | 2014-10-14 | American Sterilizer Company | Coupled enzyme-based method for electronic monitoring of biological indicator |
GB2514846B (en) * | 2013-06-07 | 2015-09-30 | Lifescan Scotland Ltd | Electrochemical-based analytical test strip with a soluble electrochemically-active coating opposite a bare electrode |
US9835578B2 (en) | 2013-06-27 | 2017-12-05 | Lifescan Scotland Limited | Temperature compensation for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte |
US9435764B2 (en) | 2013-06-27 | 2016-09-06 | Lifescan Scotland Limited | Transient signal error trap for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte |
US9435762B2 (en) * | 2013-06-27 | 2016-09-06 | Lifescan Scotland Limited | Fill error trap for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte |
US9465023B2 (en) | 2013-08-05 | 2016-10-11 | Siemens Healthcare Diagnostis Inc. | Device and method for unit use sensor testing |
US9243276B2 (en) | 2013-08-29 | 2016-01-26 | Lifescan Scotland Limited | Method and system to determine hematocrit-insensitive glucose values in a fluid sample |
US9459231B2 (en) | 2013-08-29 | 2016-10-04 | Lifescan Scotland Limited | Method and system to determine erroneous measurement signals during a test measurement sequence |
US9828621B2 (en) | 2013-09-10 | 2017-11-28 | Lifescan Scotland Limited | Anomalous signal error trap for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte |
CN106574929B (en) | 2014-07-25 | 2019-08-09 | 贝克顿·迪金森公司 | Analyte testing item test and for its implement test-strips and kit |
US20160091450A1 (en) | 2014-09-25 | 2016-03-31 | Lifescan Scotland Limited | Accurate analyte measurements for electrochemical test strip to determine analyte measurement time based on measured temperature, physical characteristic and estimated analyte value and their temperature compensated values |
US20160091451A1 (en) | 2014-09-25 | 2016-03-31 | Lifescan Scotland Limited | Accurate analyte measurements for electrochemical test strip to determine analyte measurement time based on measured temperature, physical characteristic and estimated analyte value |
EP4191239A1 (en) | 2014-12-19 | 2023-06-07 | Roche Diagnostics GmbH | Test element for electrochemically detecting at least one analyte |
JP6783109B2 (en) * | 2015-10-15 | 2020-11-11 | アークレイ株式会社 | Biosensor |
KR102296827B1 (en) * | 2019-11-08 | 2021-09-01 | 재단법인대구경북과학기술원 | Implantable biosensor |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3150958A (en) * | 1958-11-27 | 1964-09-29 | Elektrokemisk As | Process for the reduction of metals from oxide |
US3264092A (en) * | 1963-06-20 | 1966-08-02 | Mcdowell Wellman Eng Co | System for producing carbonized and metallized iron ore pellets |
US3323901A (en) * | 1965-03-17 | 1967-06-06 | Elektrokemish As | Process of pelletizing ores |
US3490895A (en) * | 1966-11-04 | 1970-01-20 | Trafik Ab | Process for cold-hardening of shaped bodies |
US3437474A (en) * | 1967-10-02 | 1969-04-08 | Blocked Iron Corp | Method of making ore agglomerates |
US3617254A (en) * | 1969-03-12 | 1971-11-02 | Blocked Iron Corp | Method of making ore agglomerates |
US3714846A (en) * | 1971-02-23 | 1973-02-06 | Sundstrand Corp | Hydrostatic-differential transmission |
US4093488A (en) * | 1973-03-16 | 1978-06-06 | Isovolta Osterreichische Isolierstoffwerk Aktiengesellschaft | Process for the production of building material elements, particularly building boards |
US3938987A (en) * | 1973-04-23 | 1976-02-17 | Mcdowell-Wellman Engineering Company | Process for preparing a smelter furnace charge composition |
US4168966A (en) * | 1975-06-14 | 1979-09-25 | Nippon Steel Corporation | Agglomerates for use in a blast furnace and method of making the same |
US4049435A (en) * | 1976-04-22 | 1977-09-20 | Valery Efimovich Lotosh | Method for obtaining a lump product |
US4528209A (en) * | 1978-10-25 | 1985-07-09 | General Electric Company | Use of amalgams in solenoidal electric field lamps |
BR8205577A (en) * | 1981-09-24 | 1983-08-30 | Sumitomo Metal Ind | PROCESS TO PRODUCE A COLD AGGLOMERED IRON ORE |
JPS59157229A (en) * | 1983-02-28 | 1984-09-06 | Nippon Kokan Kk <Nkk> | Method and device for producing non-calcined lump ore |
US5030310A (en) | 1985-06-28 | 1991-07-09 | Miles Inc. | Electrode for electrochemical sensors |
US4813538A (en) * | 1987-03-19 | 1989-03-21 | Blackman Seymour N | Re-usable sterile parenteral fluid medication administration kit |
JPH0796689B2 (en) * | 1989-06-20 | 1995-10-18 | 日本鋼管株式会社 | Manufacturing method of unfired pellets |
DE4331596A1 (en) * | 1993-09-17 | 1995-03-23 | Boehringer Mannheim Gmbh | Method for the quantitative analysis of sample liquids |
US5762770A (en) * | 1994-02-21 | 1998-06-09 | Boehringer Mannheim Corporation | Electrochemical biosensor test strip |
AUPM506894A0 (en) | 1994-04-14 | 1994-05-05 | Memtec Limited | Novel electrochemical cells |
DE4430023A1 (en) | 1994-08-24 | 1996-02-29 | Boehringer Mannheim Gmbh | Electrochemical sensor |
US5651869A (en) | 1995-02-28 | 1997-07-29 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
JP3498105B2 (en) | 1995-04-07 | 2004-02-16 | アークレイ株式会社 | Sensor, method for manufacturing the same, and measuring method using the sensor |
GB2304628B (en) | 1995-09-07 | 1998-09-23 | Kodak Ltd | Printing plate product |
US5972199A (en) | 1995-10-11 | 1999-10-26 | E. Heller & Company | Electrochemical analyte sensors using thermostable peroxidase |
AUPP238898A0 (en) | 1998-03-12 | 1998-04-09 | Usf Filtration And Separations Group Inc. | Heated electrochemical cell |
AUPN661995A0 (en) | 1995-11-16 | 1995-12-07 | Memtec America Corporation | Electrochemical cell 2 |
US5708247A (en) * | 1996-02-14 | 1998-01-13 | Selfcare, Inc. | Disposable glucose test strips, and methods and compositions for making same |
US6306584B1 (en) * | 1997-01-21 | 2001-10-23 | President And Fellows Of Harvard College | Electronic-property probing of biological molecules at surfaces |
CO5040209A1 (en) | 1997-10-16 | 2001-05-29 | Abbott Lab | BIOSENSOR ELECTRODES MEDIATORS OF COFACTOR REGENERATION |
US6652734B1 (en) | 1999-03-16 | 2003-11-25 | Lifescan, Inc. | Sensor with improved shelf life |
AUPP250398A0 (en) | 1998-03-20 | 1998-04-23 | Usf Filtration And Separations Group Inc. | Sensor with improved shelf life |
JP3004265B1 (en) * | 1998-11-24 | 2000-01-31 | 株式会社神戸製鋼所 | Carbon material interior pellet and reduced iron production method |
US6409964B1 (en) * | 1999-11-01 | 2002-06-25 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Natural Resources | Cold bonded iron particulate pellets |
EP1235068B1 (en) | 1999-11-15 | 2006-01-25 | ARKRAY, Inc. | Biosensor |
US6558528B1 (en) * | 2000-12-20 | 2003-05-06 | Lifescan, Inc. | Electrochemical test strip cards that include an integral dessicant |
US6565623B2 (en) * | 2001-03-20 | 2003-05-20 | Startec Iron Llc | Method and apparatus for curing self-reducing agglomerates |
US6855243B2 (en) * | 2001-04-27 | 2005-02-15 | Lifescan, Inc. | Electrochemical test strip having a plurality of reaction chambers and methods for using the same |
-
2000
- 2000-02-02 US US09/497,269 patent/US6716577B1/en not_active Expired - Lifetime
-
2001
- 2001-01-25 DE DE60140600T patent/DE60140600D1/en not_active Expired - Lifetime
- 2001-01-25 JP JP2001558050A patent/JP4070999B2/en not_active Expired - Lifetime
- 2001-01-25 AT AT01906688T patent/ATE449961T1/en not_active IP Right Cessation
- 2001-01-25 CZ CZ20022946A patent/CZ20022946A3/en unknown
- 2001-01-25 MX MXPA02005796A patent/MXPA02005796A/en active IP Right Grant
- 2001-01-25 KR KR1020027009856A patent/KR100856342B1/en active IP Right Grant
- 2001-01-25 ES ES01906688T patent/ES2334883T3/en not_active Expired - Lifetime
- 2001-01-25 WO PCT/US2001/002510 patent/WO2001057238A2/en active IP Right Grant
- 2001-01-25 PL PL01358134A patent/PL358134A1/en not_active Application Discontinuation
- 2001-01-25 AU AU34569/01A patent/AU778966C/en not_active Expired
- 2001-01-25 CN CN01803358A patent/CN1394278A/en active Pending
- 2001-01-25 EP EP01906688A patent/EP1254365B1/en not_active Expired - Lifetime
- 2001-01-25 CA CA2388272A patent/CA2388272C/en not_active Expired - Lifetime
- 2001-01-25 IL IL14966101A patent/IL149661A0/en unknown
- 2001-01-25 RU RU2002113054/28A patent/RU2256171C2/en active
- 2001-01-31 MY MYPI20010426A patent/MY133963A/en unknown
- 2001-02-01 AR ARP010100478A patent/AR027347A1/en unknown
- 2001-02-02 TW TW090102107A patent/TW593680B/en not_active IP Right Cessation
-
2003
- 2003-03-18 HK HK03102011.8A patent/HK1050047B/en not_active IP Right Cessation
- 2003-09-17 US US10/666,788 patent/US7498132B2/en not_active Expired - Fee Related
-
2005
- 2005-03-22 AU AU2005201227A patent/AU2005201227B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
CN1394278A (en) | 2003-01-29 |
CZ20022946A3 (en) | 2003-04-16 |
JP4070999B2 (en) | 2008-04-02 |
AU2005201227A1 (en) | 2005-04-14 |
IL149661A0 (en) | 2002-11-10 |
AU778966C (en) | 2005-09-29 |
ATE449961T1 (en) | 2009-12-15 |
EP1254365A2 (en) | 2002-11-06 |
WO2001057238A2 (en) | 2001-08-09 |
RU2002113054A (en) | 2004-01-27 |
US6716577B1 (en) | 2004-04-06 |
AU2005201227B2 (en) | 2007-08-30 |
AR027347A1 (en) | 2003-03-26 |
ES2334883T3 (en) | 2010-03-17 |
MXPA02005796A (en) | 2003-10-14 |
AU3456901A (en) | 2001-08-14 |
US20040058433A1 (en) | 2004-03-25 |
JP2003524162A (en) | 2003-08-12 |
RU2256171C2 (en) | 2005-07-10 |
KR20020077407A (en) | 2002-10-11 |
PL358134A1 (en) | 2004-08-09 |
TW593680B (en) | 2004-06-21 |
US7498132B2 (en) | 2009-03-03 |
HK1050047B (en) | 2010-08-13 |
EP1254365B1 (en) | 2009-11-25 |
DE60140600D1 (en) | 2010-01-07 |
HK1050047A1 (en) | 2003-06-06 |
CA2388272C (en) | 2011-05-10 |
KR100856342B1 (en) | 2008-09-04 |
WO2001057238A3 (en) | 2002-04-18 |
MY133963A (en) | 2007-11-30 |
AU778966B2 (en) | 2004-12-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2388272A1 (en) | Electrochemical test strip for use in analyte determination | |
EP1021720B1 (en) | Electrochemical determination of fructosamine | |
Baldwin | Recent advances in electrochemical detection in capillary electrophoresis | |
CA2222525C (en) | Electrochemical cell | |
AU6157898A (en) | Small volume (in vitro) analyte sensor | |
US20040217016A1 (en) | Electrochemical test strip having a plurality of reaction chambers and methods for using the same | |
Cui et al. | Disposable amperometric glucose sensor electrode with enzyme-immobilized nitrocellulose strip | |
CA2069946A1 (en) | Redox mediator reagent and biosensor | |
CA2167822A1 (en) | Potentiometric biosensor and the method for its use | |
DE69915850D1 (en) | SMALL VOLUME IN VITRO SENSOR WITH DIFFUSIONABLE OR NON-WASHABLE REDOX AGENT | |
RU2002135727A (en) | ELECTROCHEMICAL ELEMENT | |
CA2530211A1 (en) | Electrochemical affinity biosensor system and methods | |
US20100089774A1 (en) | Non-enzymatic electrochemical method for simultaneous determination of total hemoglobin and glycated hemoglobin | |
Yuan et al. | Characterization of Prolidase Activity Using Capillary Electrophoresis with Tris (2, 2 ‘-bipyridyl) ruthenium (II) Electrochemiluminescence Detection and Application To Evaluate Collagen Degradation in Diabetes Mellitus | |
Markas | Rapid detection of paracetamol using a disposable, surface-modified screen-printed carbon electrode | |
Situmorang et al. | Flow injection potentiometry for enzymatic assay of cholesterol with a tungsten electrode sensor | |
Mohammadi et al. | Determination of mercury (II) by invertase enzyme inhibition coupled with batch injection analysis | |
Hart et al. | Sensors/biosensors, based on screen-printing technology for biomedical applications | |
EP1936375B1 (en) | Non-enzymatic disposable electrode strip comprising a surfactant for detecting uric acid; method for producing the same and its use | |
CN113866235B (en) | Electrochemiluminescence-colorimetric dual-mode sensing detection device based on closed bipolar electrode and construction method and application thereof | |
Reiter et al. | Redox modification of proteins using sequential-parallel electrochemistry in microtiter plates | |
Abdullin et al. | Determination of uric acid by voltammetry and coulometric titration | |
Schwarz | Enzyme‐catalyzed amperometric oxidation of neurotransmitters in chip‐capillary electrophoresis | |
US20060099666A1 (en) | Analyzer for the simultaneous enzymatic detection of closely related analytes | |
Backofen et al. | Determination of cyanide in microsamples by means of capillary flow injection analysis with amperometric detection |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20210125 |