CA2390248A1 - Apparatus for mechanical perfusion of a donor's organ during its transport - Google Patents

Apparatus for mechanical perfusion of a donor's organ during its transport Download PDF

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Publication number
CA2390248A1
CA2390248A1 CA002390248A CA2390248A CA2390248A1 CA 2390248 A1 CA2390248 A1 CA 2390248A1 CA 002390248 A CA002390248 A CA 002390248A CA 2390248 A CA2390248 A CA 2390248A CA 2390248 A1 CA2390248 A1 CA 2390248A1
Authority
CA
Canada
Prior art keywords
organ
donor
receptacle
transport
organ during
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002390248A
Other languages
French (fr)
Other versions
CA2390248C (en
Inventor
Benedict Marie Doorschodt
Joris Emanuel Nicolaas Jaspers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universiteit Van Amsterdam
Original Assignee
Universiteit Van Amsterdam
Benedict Marie Doorschodt
Joris Emanuel Nicolaas Jaspers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universiteit Van Amsterdam, Benedict Marie Doorschodt, Joris Emanuel Nicolaas Jaspers filed Critical Universiteit Van Amsterdam
Publication of CA2390248A1 publication Critical patent/CA2390248A1/en
Application granted granted Critical
Publication of CA2390248C publication Critical patent/CA2390248C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/06—Pumps having fluid drive
    • F04B43/073—Pumps having fluid drive the actuating fluid being controlled by at least one valve
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts

Abstract

The invention relates to an apparatus for mechanical organ perfusion during the transport phase of a donor organ, which apparatus comprises an organ receptacle for accommodating the organ, propulsion means for moving the perfusate contained in a liquid compartment of the apparatus to and through the organ receptacle, and oxygenation means for the aeration of the organ receptacle.
The propulsion means are embodied as a pump driven by compressed air, while the compressed air serves at the same time for the aeration of the organ receptacle.
CA002390248A 1999-11-08 2000-11-08 Apparatus for mechanical perfusion of a donor's organ during its transport Expired - Lifetime CA2390248C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL1013524A NL1013524C2 (en) 1999-11-08 1999-11-08 Machine for organ perfusion during the transport phase of a donor organ.
NL1013524 1999-11-08
PCT/NL2000/000814 WO2001033959A2 (en) 1999-11-08 2000-11-08 Apparatus for mechanical perfusion of a donor's organ during its transport

Publications (2)

Publication Number Publication Date
CA2390248A1 true CA2390248A1 (en) 2001-05-17
CA2390248C CA2390248C (en) 2009-02-17

Family

ID=19770217

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002390248A Expired - Lifetime CA2390248C (en) 1999-11-08 2000-11-08 Apparatus for mechanical perfusion of a donor's organ during its transport

Country Status (10)

Country Link
US (1) US6905871B1 (en)
EP (1) EP1229788B1 (en)
JP (1) JP4790182B2 (en)
AT (1) ATE286653T1 (en)
AU (1) AU778083B2 (en)
CA (1) CA2390248C (en)
DE (1) DE60017448T2 (en)
ES (1) ES2236002T3 (en)
NL (1) NL1013524C2 (en)
WO (1) WO2001033959A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040170950A1 (en) * 2002-09-12 2004-09-02 Prien Samuel D. Organ preservation apparatus and methods
NL1024022C2 (en) * 2003-07-30 2005-02-01 Technologiestichting Stw Portable preservation device for a donor organ.
US20050153271A1 (en) * 2004-01-13 2005-07-14 Wenrich Marshall S. Organ preservation apparatus and methods
NL1028848C2 (en) * 2005-04-22 2006-10-24 Doorzand Airdrive B V Device for transporting an organ.
JP2009524693A (en) * 2006-01-27 2009-07-02 トランスプラン， インコーポレイテッド Non-recirculating organ perfusion device
US20080145919A1 (en) * 2006-12-18 2008-06-19 Franklin Thomas D Portable organ and tissue preservation apparatus, kit and methods
WO2010036726A1 (en) * 2008-09-23 2010-04-01 Cedars-Sinai Medical Center Methods and apparatus for perfusion of an explanted donor heart
US9320269B2 (en) * 2009-09-25 2016-04-26 John Brassil Organ preservation system
US8828710B2 (en) 2011-03-15 2014-09-09 Paragonix Technologies, Inc. System for hypothermic transport of samples
US9867368B2 (en) 2011-03-15 2018-01-16 Paragonix Technologies, Inc. System for hypothermic transport of samples
US8835158B2 (en) 2011-03-15 2014-09-16 Paragonix Technologics, Inc. Apparatus for oxygenation and perfusion of tissue for organ preservation
US11178866B2 (en) 2011-03-15 2021-11-23 Paragonix Technologies, Inc. System for hypothermic transport of samples
US9253976B2 (en) 2011-03-15 2016-02-09 Paragonix Technologies, Inc. Methods and devices for preserving tissues
US9426979B2 (en) 2011-03-15 2016-08-30 Paragonix Technologies, Inc. Apparatus for oxygenation and perfusion of tissue for organ preservation
ES2585880T3 (en) 2011-09-02 2016-10-10 Organ Assist B.V. Apparatus, system and method for conditioning and preserving an organ of a donor
US8785116B2 (en) 2012-08-10 2014-07-22 Paragonix Technologies, Inc. Methods for evaluating the suitability of an organ for transplant
US9560846B2 (en) 2012-08-10 2017-02-07 Paragonix Technologies, Inc. System for hypothermic transport of biological samples
USD765874S1 (en) 2014-10-10 2016-09-06 Paragonix Technologies, Inc. Transporter for a tissue transport system
EP3634127A4 (en) 2017-06-07 2021-03-17 Paragonix Technologies Inc. Apparatus for tissue transport and preservation
US11632951B2 (en) 2020-01-31 2023-04-25 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2241698C2 (en) * 1971-09-02 1982-08-26 Roland Dr.med. Zürich Doerig Process for organ preservation and device for carrying out this process
US4350477A (en) * 1977-04-20 1982-09-21 Mazal Charles N Pneumatic pulsatile fluid pump
IE930532A1 (en) * 1993-07-19 1995-01-25 Elan Med Tech Liquid material dispenser and valve
US5362622A (en) * 1993-03-11 1994-11-08 Board Of Regents, The University Of Texas System Combined perfusion and oxygenation apparatus
DE4342728A1 (en) * 1993-12-15 1995-06-22 Thomae Gmbh Dr K Aq. isotonic soln. for perfusion and preservation of explanted liver
US5965433A (en) * 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate
US6677150B2 (en) * 2001-09-14 2004-01-13 Organ Transport Systems, Inc. Organ preservation apparatus and methods

Also Published As

Publication number Publication date
NL1013524C2 (en) 2001-05-09
ES2236002T3 (en) 2005-07-16
AU778083B2 (en) 2004-11-18
WO2001033959A2 (en) 2001-05-17
AU1741301A (en) 2001-06-06
CA2390248C (en) 2009-02-17
EP1229788B1 (en) 2005-01-12
JP2004500345A (en) 2004-01-08
ATE286653T1 (en) 2005-01-15
DE60017448D1 (en) 2005-02-17
EP1229788A2 (en) 2002-08-14
US6905871B1 (en) 2005-06-14
WO2001033959A3 (en) 2001-10-04
WO2001033959A9 (en) 2006-08-17
JP4790182B2 (en) 2011-10-12
DE60017448T2 (en) 2006-01-12

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Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20201109