CA2405224A1 - Deep organ access device and method - Google Patents

Deep organ access device and method Download PDF

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Publication number
CA2405224A1
CA2405224A1 CA002405224A CA2405224A CA2405224A1 CA 2405224 A1 CA2405224 A1 CA 2405224A1 CA 002405224 A CA002405224 A CA 002405224A CA 2405224 A CA2405224 A CA 2405224A CA 2405224 A1 CA2405224 A1 CA 2405224A1
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CA
Canada
Prior art keywords
instrument
guide
further including
sheath
axis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002405224A
Other languages
French (fr)
Other versions
CA2405224C (en
Inventor
James G. Skakoon
Robert Wharen
Matthew S. Solar
Kari Parmer
Rudy A. Mazzocchi
John David
Frank Murdock
David Hatcher
Thomas I. Miller
Timothy Alan Parmer
Charles L. Truwit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mayo Foundation for Medical Education and Research
Medtronic Inc
Original Assignee
Image-Guided Neurologics, Inc.
James G. Skakoon
Robert Wharen
Matthew S. Solar
Kari Parmer
Rudy A. Mazzocchi
John David
Frank Murdock
David Hatcher
Thomas I. Miller
Timothy Alan Parmer
Charles L. Truwit
Mayo Foundation For Medical Education And Research
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Filing date
Publication date
Application filed by Image-Guided Neurologics, Inc., James G. Skakoon, Robert Wharen, Matthew S. Solar, Kari Parmer, Rudy A. Mazzocchi, John David, Frank Murdock, David Hatcher, Thomas I. Miller, Timothy Alan Parmer, Charles L. Truwit, Mayo Foundation For Medical Education And Research filed Critical Image-Guided Neurologics, Inc.
Publication of CA2405224A1 publication Critical patent/CA2405224A1/en
Application granted granted Critical
Publication of CA2405224C publication Critical patent/CA2405224C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0539—Anchoring of brain electrode systems, e.g. within burr hole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B90/11—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0534—Electrodes for deep brain stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/0023—Surgical instruments, devices or methods, e.g. tourniquets disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00367—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
    • A61B2017/00398—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like using powered actuators, e.g. stepper motors, solenoids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831—Material properties
    • A61B2017/00902—Material properties transparent or translucent
    • A61B2017/00911—Material properties transparent or translucent for fields applied by a magnetic resonance imaging system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3403—Needle locating or guiding means
    • A61B2017/3405—Needle locating or guiding means using mechanical guide means
    • A61B2017/3407—Needle locating or guiding means using mechanical guide means including a base for support on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3403—Needle locating or guiding means
    • A61B2017/3405—Needle locating or guiding means using mechanical guide means
    • A61B2017/3409—Needle locating or guiding means using mechanical guide means including needle or instrument drives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3403—Needle locating or guiding means
    • A61B2017/3405—Needle locating or guiding means using mechanical guide means
    • A61B2017/3411—Needle locating or guiding means using mechanical guide means with a plurality of holes, e.g. holes in matrix arrangement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B2017/347—Locking means, e.g. for locking instrument in cannula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2046—Tracking techniques
    • A61B2034/2051—Electromagnetic tracking systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2046—Tracking techniques
    • A61B2034/2055—Optical tracking systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B2090/103—Cranial plugs for access to brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B2090/363—Use of fiducial points
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/374—NMR or MRI
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/376—Surgical systems with images on a monitor during operation using X-rays, e.g. fluoroscopy
    • A61B2090/3762—Surgical systems with images on a monitor during operation using X-rays, e.g. fluoroscopy using computed tomography systems [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3983—Reference marker arrangements for use with image guided surgery

Abstract

Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems.

Claims (77)

1. An access device including:
a mounting unit having a mounting plane;
a primary guide assembly that defines at least one insertion axis;
a rotating joint, attaching the guide assembly to the support structure, the rotating joint allowing rotation of the primary guide structure about a rotation axis normal to the mounting plane;
a first locking device that fixes an orientation of the rotating joint;
an arcuate sliding joint, attaching the guide assembly to the support structure, the arcuate sliding joint capable of adjusting an insertion angle of at least one insertion axis with respect to the mounting plane;
a second locking device, associated with the arcuate sliding joint, that fixes the insertion angle within a range of motion;
a ball and socket joint, coupled to the arcuate sliding joint, allowing further adjustment of the insertion angle; and a third locking device that fixes the ball and socket joint within a range of motion.
2. The access device of claim 1, in which the primary guide assembly is detachable from the ball-and-socket joint, a portion of the primary guide assembly fitting within a ball of the ball-and-socket joint using a tapered outside surface so that the primary guide assembly is held in the ball by a wedge formed by the tapered outside surface.
3. The access device of claim 1, in which the ball-and-socket joint further includes a plurality of ball adjustment contacts. each ball adjustment contact being adjustable with respect to a socket of the ball-and-socket joint, and each ball adjustment contact being in communication with the ball.
4. The access device of claim 3, in which the plurality of ball adjustment contacts include threaded members that are threaded through the socket, and contact the ball.
5. The access device of claim 1, further including a reference device coupled to the primary guide assembly wherein the reference device locates at least one of the insertion axes.
6. The access device of claim 5, in which the reference device includes a number of light emitting diodes.
7. The access device of claim 5, in which the reference device includes a number of light reflectors.
8. The access device of claim 5, in which the reference device includes one or more electrical coils.
9. The access device of claim 1, in which the at least one insertion axis includes a central insertion axis and a peripheral insertion axis.
10. The access device of claim 1, in which the at least one insertion axis includes a central insertion axis and four peripheral insertion axes.
11. The access device of claim l, further including a secondary guide device, having a secondary insertion axis, the secondary guide device being coupled to the primary guide assembly.
12. The access device of claim 11, in which the secondary insertion axis is collinear with the central insertion axis.
13. The access device of claim 11, in which the secondary insertion axis is collinear with one of the peripheral insertion axes.
14. The access device of claim 1, further including an alignment device coupled to the primary guide assembly, a portion of the alignment device being visible using an imaging device.
15. The access device of claim 14, in which the alignment device includes a fluid filled stem that is visible using magnetic resonance imaging (MRI).
16. The access device of claim 14, further including a processor that indicates when the insertion axis is aligned with a target within a patient.
17. The access device of claim 1, further including at least one sheath adapted for insertion through the primary guide assembly.
18. The access device of claim 17, further including at least one stylet adapted for insertion through the at least one sheath.
19. The access device of claim 18, in which the sheath covers a first longitudinal portion of the stylet, leaving a second longitudinal portion of the stylet exposed.
20. The access device of claim 17, in which the sheath includes a peel-away portion.
21. The access device of claim 17, in which the sheath includes:
a first sheath portion; and a second sheath portion capable of rotating with respect to the first sheath portion such that when rotated from a first position to a second position a longitudinal sheath opening is exposed.
22. The access device of claim 1, further including a device introducer that controllably moves a primary device along the insertion axis.
23. The access device of claim 22, in which the device introducer includes a locally mounted indicator device that is capable of locating a position of a primary medical device along the insertion axis.
24. The access device of claim 23, in which the locally mounted indicator device includes at least one of a linear encoder and a potentiometer.
25. The access device of claim 1, further including a fixing device coupled to the mounting unit, the fixing device being capable of fixing the location of a primary device along the insertion axis.
26. The access device of claim 25, wherein the fixing device includes:
a body, the body having an opening with a first surface;
a fixing unit, the fixing unit having a second surface that is adjustable with respect to the first surface; and a locking device capable of holding the fixing unit in a position with respect to the body such that the first and second surfaces engage the primary medical device, fixing it in a location along the insertion axis.
27. The access device of claim 26, further including a cap that is capable of substantially covering an insertion opening in the mounting unit.
28. The access device of claim 27, further including a groove that allows a primary device to remain fixed in a location along the insertion axis, while the insertion opening is covered with the cap.
29. The access device of claim 1, further including a removable centering device, the removable centering device including:
a centering body;
a number of insertion opening contacts coupled to the centering body;
and an attachment device that is removably coupled to the mounting unit during a mounting procedure.
30. The access device of claim 1, further including a pivot joint, attaching the guide assembly to the support structure, the pivot joint capable of adjusting a first insertion angle of at least one insertion axis with respect to a first direction in the mounting plane.
31. A primary device retention system including:

a base having a mounting plane and an insertion opening, the base being capable of being attached to a body; and a fixing device coupled to the base such that the fixing device is capable of rotating about an axis normal to the mounting plane, the fixing device being capable of fixing the location of a primary device within the body.
32. The system of claim 31, wherein the fixing device includes:
a first portion, the first portion having an opening that includes a first surface;
a second portion, the second portion having a second surface that is adjustable with respect to the first surface; and a locking device capable of holding the second portion in a position with respect to the first portion such that the first and second surfaces engage the primary device, fixing it in a location within the body.
33. The system of claim 32, in which the first surface includes a radially oriented planar surface.
34. The system of claim 33, in which the base includes:
at least one opening to accommodate a proximal portion of the primary device; and the fixing device being capable of rotating the radially oriented planar surface into alignment with the at least one opening and fixing the location of the primary device within the body while the proximal portion of the primary device is routed in the at least one opening.
35. The system of claim 31, further including a cap that is capable of covering the insertion opening in the base.
36. The system of claim 31, in which the fixing device includes, attached to the base, a stabilizer to engage the instrument, the stabilizer including a movable cam to define an opening sized and shaped to immobilize the instrument.
37. The system of claim 31, in which the fixing device includes:

a resilient lower plate stabilizer to engage the instrument, the lower plate stabilizer being configured to rest on the base and including at least one flexible opening sized and shaped to at least partially surround the instrument when normally relaxed and to immobilize the instrument when compressed inwardly toward the instrument; and an upper plate that is relatively more rigid than the resilient lower plate stabilizer, configured to rest on the resilient lower plate, and comprising a feature complementary to the normally relaxed size and shape of each flexible opening of the resilient lower plate stabilizer, yet shaped and sized to compress each such flexible opening inwardly upon compression of the upper plate and lower plate together.
38. The system of claim 31, in which the fixing device includes:
attachable to the base, a resilient detachable C-shaped stabilizer to engage the instrument, the C-shaped stabilizer being configured to rest on the base and defining a flexible wedge-shaped angular opening sized and shaped to immobilize the instrument when normally relaxed yet release the instrument when expanded circumferentially away from the instrument; and attachable to the wedge-shaped opening of the C-shaped stabilizer, a separate spreader that includes a pair of surfaces angularly spaced from each other by an amount greater than the amount of the flexible wedge-shaped angular opening of the resilient C-shaped stabilizer when normally relaxed.
39. A method including:
securing a base portion of a guide lumen carrying assembly around an entry portal in a surface;
rotating at least a portion of the guide lumen carrying assembly about a first axis that is substantially concentric to the entry portal and substantially orthogonal to the surface;
tilting at least a portion of the assembly so that a second axis, extending concentrically through the guide lumen, is at a desired angle with the first axis;
spherically adjusting a portion of the guide-lumen carrying assembly to orient a trajectory provided by the second axis in a desired direction with respect to the entry portal; and fixing a position of the guide lumen.
40. The method of claim 39 in which fixing the position of the guide lumen includes at least one of: securing the rotating portion of the guide-lumen assembly; securing the tilting portion of the guide-lumen carrying assembly;
and securing the spherically adjustable portion of the guide lumen carrying assembly.
41. The method of claim 39, in which spherically adjusting includes adjusting an orientation of a ball housed in a socket.
42. The method of claim 41, in which spherically adjusting includes moving a position of the ball within the socket using at least one threaded member engaging the ball.
43. The method of claim 39, further including introducing an instrument through the guide lumen and the portal substantially along a trajectory provided by the second axis.
44. The method of claim 43, in which introducing the instrument includes introducing at least one instrument selected from the group consisting essentially of a sheath, a stylet, a guide, a primary instrument, and an electrode.
45. The method of claim 43, in which introducing the instrument includes:
coupling a sliding clamp to a portion of the guide-lumen carrying assembly;
clamping a portion of the instrument to the clamp; and advancing the sliding clamp toward the entry portal.
46. The method of claim 43, in which introducing the instrument includes:
inserting a stylet into a lumen of a sheath; and advancing the stylet and sheath through the guide lumen and the entry portal.
47. The method of claim 46, further including removing the stylet from the lumen of the sheath.
48. The method of claim 47, further including inserting an electrode into the lumen of the sheath and through the guide-lumen and through the entry portal.
49. The method of claim 48, further including retracting the sheath from the entry portal by peeling the sheath into more than one piece.
50. The method of claim 48, further including adjusting a distance by which the sheath extends into the entry portal by viewing an indicator on the sheath.
51. The method of claim 39, further including receiving, into the guide-lumen, a portion of an imagable device.
52. The method of claim 51, in which receiving the portion of the imagable device includes receiving an imagable device selected from the group consisting essentially of an MRI-imagable alignment stem, a CT-imagable alignment stem, and a frameless surgical navigation instrument.
53. The method of claim 51, in which the rotating and tilting are performed in conjunction with real-time viewing of the imagable device, using a corresponding imaging modality, to align a trajectory of the second axis with a target location located through the entry portal beyond the surface.
54. The method of claim 39, further including securing a base access plate to the surface around the entry portal;
introducing an instrument through the entry portal to a target location beyond the surface; and securing the introduced instrument to the base access plate.
55. The method of claim 54, further including concentrically aligning the base access plate to the entry portal.
56. The method of claim 55, in which the aligning includes:
inserting a screw-carrying positioner through an opening in the base access plate and into the entry portal to position the base access plate concentrically around the entry portal;
screwing the base access plate to the surface, thereby releasing the screws from the screw-carrying positioner; and removing the positioner.
57. The method of claim 54, in which securing the introduced instrument includes clamping the introduced instrument.
58. The method of claim 54, further including laterally exiting the instrument from the base plate.
59. The method of claim 39, further including capping the entry portal.
60. The method of claim 39, further including introducing an instrument through the guide lumen and the entry portal toward a target location beyond the surface of the entry portal.
61. The method of claim 60, in which the guide lumen is a first guide lumen, and further including reintroducing the instrument through a second guide lumen offset from the first guide lumen by a predetermined distance.
62. The method of claim 39, in which the guide lumen carrying assembly provides a plurality of guide lumens, and further including selecting a particular one of the guide lumens for introducing an instrument by at least one of orienting and coupling a guide lumen selector to the guide lumen carrying assembly.
63. A method including:
securing a base access plate to a surface around an entry portal;
introducing an instrument through the entry portal to a target location beyond the surface; and securing the introduced instrument to the base access plate, including selecting a radial position of the introduced instrument in an elongate opening extending from a center region of the stabilizing clamp, and clamping the introduced instrument at the selected radial position.
64. The method of claim 63, further including concentrically aligning the base access plate to the entry portal, in which the aligning includes:
inserting a screw-carrying positioner through an opening in the base access plate and into the entry portal to position the base access plate concentrically around the entry portal;
screwing the base access plate to the surface, thereby releasing the screws from the screw-carrying positioner; and removing the positioner.
65. The method of claim 63, in which securing the introduced instrument includes:
selecting an orientation of a stabilizing clamp from a full 360 degree range of available orientations with respect to the base access plate; and coupling the stabilizing clamp to the base access plate in the selected orientation.
66. The method of claim 63, further including laterally exiting the instrument from the base plate.
67. The method of claim 63, further including capping the entry portal.
68. The method of claim 63, further including:
securing a base portion of a guide lumen carrying assembly around an entry portal in a surface;
rotating at least a portion of the guide lumen carrying assembly about a first axis that is substantially concentric to the entry portal and substantially orthogonal to the surface; and slidably tilting at least a portion of the assembly so that a second axis, extending concentrically through the guide lumen, is at a desired angle with the first axis.
69. A method including:
securing a base portion of a multiple primary guide lumen carrying assembly around an entry portal in a surface;
orienting a secondary guide lumen, with respect to a plurality of coupling locations of the primary guide lumen carrying assembly, such that the secondary guide lumen aligns with a desired one of the multiple primary guide lumens;
and coupling the secondary guide lumen to the primary guide lumen carrying assembly in the selected orientation.
70. The method of claim 69, further including introducing an instrument through the secondary guide lumen and the aligned one of the primary guide lumens.
71. The method of claim 70, further including:
introducing a sheath into the aligned one of the primary guide lumens;
and holding the sheath at the secondary guide lumen as the instrument is inserted through the secondary guide lumen and the aligned one of the primary guide lumens through the sheath.
72. The method of claim 71, further including securing the instrument near the secondary guide lumen before removing the sheath.
73. The method of claim 72, in which removing the sheath includes pulling the sheath out in a plurality of pieces.
74. A method including:
introducing a sheath through a portal in a surface to a target location;
introducing an instrument through the sheath to the target location;

rotating first and second portions of the sheath with respect to each other to create an access opening in the sheath above the surface of the portal, thereby exposing a portion of the instrument;
securing an exposed portion of the instrument; and removing the sheath.
75. A method including:
securing a base portion of a guide lumen carrying assembly around an entry portal in a surface, the guide lumen providing a trajectory axis, and the body portal providing a portal normal axis that is orthogonal to the surface of the body portal;
adjusting an angle between the trajectory axis and the portal normal axis by pivoting an arcuate portion of the guide lumen carrying assembly with respect to the base; and adjusting the angle between the trajectory axis and the portal normal axis by sliding a portion of the guide lumen carrying assembly along the arcuate portion of the guide lumen carrying assembly.
76. The method of claim 75, further including spherically adjusting the guide lumen with respect to the arcuate portion of the guide lumen carrying assembly.
77. The method of claim 75, further including introducing a primary device along the trajectory axis.
CA2405224A 2000-04-07 2001-04-06 Deep organ access device and method Expired - Fee Related CA2405224C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19566300P 2000-04-07 2000-04-07
US60/195,663 2000-04-07
PCT/US2001/011178 WO2001076498A2 (en) 2000-04-07 2001-04-06 Deep organ access device and method

Publications (2)

Publication Number Publication Date
CA2405224A1 true CA2405224A1 (en) 2001-10-18
CA2405224C CA2405224C (en) 2010-02-23

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CA2405224A Expired - Fee Related CA2405224C (en) 2000-04-07 2001-04-06 Deep organ access device and method

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US (11) US7660621B2 (en)
EP (1) EP1272120B8 (en)
AT (1) ATE384483T1 (en)
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US20020156372A1 (en) 2002-10-24
US10300268B2 (en) 2019-05-28
WO2001076498A3 (en) 2002-04-18
US20020010479A1 (en) 2002-01-24
ATE384483T1 (en) 2008-02-15
US20150100064A1 (en) 2015-04-09
WO2001076498B1 (en) 2002-06-27
US20110022058A1 (en) 2011-01-27
EP1272120B1 (en) 2008-01-23
US20070255275A1 (en) 2007-11-01
US7660621B2 (en) 2010-02-09
US8911452B2 (en) 2014-12-16
AU2001289311A1 (en) 2001-10-23
DE60132569T2 (en) 2009-02-19
US7857820B2 (en) 2010-12-28
US7204840B2 (en) 2007-04-17
WO2001076498A9 (en) 2003-10-09
CA2405224C (en) 2010-02-23
US8845656B2 (en) 2014-09-30
US20080082108A1 (en) 2008-04-03
AU2001251371A1 (en) 2001-10-23
US20070250077A1 (en) 2007-10-25
US20110022059A1 (en) 2011-01-27
EP1272120B8 (en) 2008-03-26
US20070250076A1 (en) 2007-10-25
US7833231B2 (en) 2010-11-16
US7815651B2 (en) 2010-10-19
US20070250075A1 (en) 2007-10-25
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US7235084B2 (en) 2007-06-26

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