CA2414022A1 - Annuloplasty devices - Google Patents

Annuloplasty devices Download PDF

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Publication number
CA2414022A1
CA2414022A1 CA002414022A CA2414022A CA2414022A1 CA 2414022 A1 CA2414022 A1 CA 2414022A1 CA 002414022 A CA002414022 A CA 002414022A CA 2414022 A CA2414022 A CA 2414022A CA 2414022 A1 CA2414022 A1 CA 2414022A1
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CA
Canada
Prior art keywords
valve
support
rings
ring
coil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002414022A
Other languages
French (fr)
Other versions
CA2414022C (en
Inventor
Paul A. Spence
Mark Ortiz
Randy Whedon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtentia International Ltd Oy
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Priority to CA2673614A priority Critical patent/CA2673614C/en
Publication of CA2414022A1 publication Critical patent/CA2414022A1/en
Application granted granted Critical
Publication of CA2414022C publication Critical patent/CA2414022C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2445Annuloplasty rings in direct contact with the valve annulus
    • A61F2/2448D-shaped rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2409Support rings therefor, e.g. for connecting valves to tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2445Annuloplasty rings in direct contact with the valve annulus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2466Delivery devices therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427Devices for manipulating or deploying heart valves during implantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2454Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
    • A61F2/2457Chordae tendineae prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A61F2210/0023Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
    • A61F2210/0033Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply electrically, e.g. heated by resistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0091Three-dimensional shapes helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/006Additional features; Implant or prostheses properties not otherwise provided for modular

Abstract

Devices for repairing and replacing a heart valve (18) in various embodiments, the devices (42) include at least first and second support rings connected together in a coiled configuration to abut opposite sides of a valve annulus (20). A replacement valve (260) may be secured to the coil-shaped device (262). Various alternative fastening systems include suture fastening systems, mechanical fastening systems, shape memory alloy fastening systems and other fastening systems relying only on the resilience between adjacent coils. A
method generally includes inserting a first end of the coil-shaped member (42) through a valve annulus (20), rotating a first ring of the coil-shaped member (42) into position on one side of the valve annulus (20) and positioning at least a second ring of the coil-shaped member (42) on an opposite side of the valve annulus (20).

Claims (59)

1. A device for repairing a heart valve comprises of valve tissue including an annulus and a plurality of leaflets for allowing and preventing blood flows the device comprising a support member (42, 42', 42". 52, 70, 80, 90, 120, 150: 162, 180, 200, 212, 217, 218, 219, 220, 226, 240, 250, 262, 260, 270, 280, 300, 310, 340, 362) comprising a first support ring, the first support ring configured to abut one side of the valve (18), characterised in that the support member (42, 42', 42", 52, 70, 80, 90, 120, 150, 162, 180, 200, 212, 217, 218, 219, 220, 226, 240, 250, 262. 260, 270, 280, 300, 310, 340, 362) comprises a second support ring connected to the first support ring to form a coiled configuration, the second support ring configured to abut an opposite side of the valve to thereby trap a portion of the valve tissue between it and the first support ring.
2. The device of Claim 1, wherein said first and second support rings each have an inner core (44, 44", 110, 152, 160, 228, 244, 342) covered by an outer layer (46, 82, 344), said inner core (44, 44", 110, 152, 160, 228, 244, 342) formed from a more rigid material than said outer layer (46, 82, 344).
3. The device of Claim 1, further comprising a removable material (84) on at least one of said first and second support rings (80) for reducing friction between the respective rings and the valve tissue during initial engagement therewith, said material (84) being removable to increase the friction during securement of the device to the valve tissue.
4. The device of Claim 1 wherein opposed surfaces of said first and second support rings (90) are roughened to facilitate engagement with the valve tissue.
5. The device of Claim 4, further comprising a coating of cushioning material (94, 96) on each of said opposed surfaces.
6. The device of Claim 1, wherein each of said support rings (80, 150, 212, 226, 362) is formed from a fabric material.
7. The device of Claim 1, wherein at least one of said support rings (218, 300) includes undulations.
8. The device of Claim 1, wherein said support rings (217, 218) are formed from a flat plate material.
9. The device of Claim 1, wherein said first and second support rings have a multi-layered construction including an inner layer (228) of a first material and an outer layer (230) of a second material, said inner layer having a lower coefficient of friction than said outer layer, and said inner layer being exposed on opposed surfaces (228a) of said first and second support rings which are adapted to engage the valve tissue therebetween.
10. The device of Claim 1, wherein said first and second support rings (270) are adjustable in diameter to allow adjustment of the valve annulus.
11. The device of Claim 1, wherein said first and second support rings (42', 110) have generally triangular-shaped cross-sections.
12. The device of Claim 1, wherein said first and second support rings ( 7 0) ace formed from a shape memory alloy.
13. The device of any preceding claim, wherein said first and second support rings (42, 42', 42", 52, 70, 80, 90, 120, 150, 162, 180, 200, 212, 217, 218, 219, 220, 226, 240, 250, 262, 260, 270, 280, 300, 310, 340, 362) are formed integrally from a coiled rod with one end of said rod formed a leading end on said first support ring and another end of said rod forming a trailing end on said second support ring.
14. The device of Claim 13, wherein said leading and trailing ends (220a, 222b) are bent in generally opposite directions.
15. The device of any preceding claim, further comprising a plurality of fasteners (44, 44a", 54, 70a, 70b, 92, 114, 124, 164, 168, 219a, 219b, 248, 252) extending between said first and second support rings.
16. The device of Claim 15, wherein said fasteners comprise sharp projections (44a, 44a", 114, 248).
17. The device of Claim 15, wherein said fasteners comprise at least one projection (70a, 164) extending from said first support ring and at feast one receiving member (70b, 168) on said second support ring configured to engage with said projection.
18. The device of Claim 15, further comprising an actuating member (60. 112) coupled to at least one of said support rings and operating to actuate the fasteners (44a, 44a", 114) to an extended position through the valve tissue.
19. The device of any preceding claim, further comprising a removable carrier (40, 100, 242, 290) configured to carry said first and second support rings into position on opposite sides of the valve and then be removed leaving said first and second support rings on opposite sides of the valve.
20. A device for repairing a heart valve comprised of valve tissue including an annulus and a plurality of leaflets for allowing and preventing blood flaw, the device comprising.

a valve support device configured for attachment to at least one side of the heart valve, and a coil-shaped carrier removably coupled with said valve support device for allowing said valve support device to be turned into position on said at least one side and secured to a portion of the valve tissue to support the heart valve.
21 . A device for repairing a heart valve comprised of valve tissue including an annulus and a plurality of leaflets for allowing and preventing blood floor, the device comprising:

& catheter having a lumen and an open end.

an elongate valve support member carried within said lumen and movable from said open end, said elongate valve support member having an uncoiled configuration within said lumen and assuming a coiled configuration when extended from said open end.
22. The device of claim 21, wherein said elongate valve support member including an inner core covered by an outer layer, said inner core formed from a more rigid material than said outer layer.
23. The device of claim 21, wherein said elongate valve support member has a generally triangular-shaped cross section.
24. The device of 21 further comprising:
an actuator carried within said lumen and operable to extend said elongate valve support member from said open end.
25. The device of claim 24, wherein said actuator further comprises a gripping element operable to grip and allow releasing of one end of said elongate valve support member.
26. The device of claim 21, wherein said elongate valve support member is formed from a shape memory alloy.
27. A device for repairing a heart valve comprised of valve tissue including an annulus and a plurality of leaflets for allowing and preventing blood flow, the device comprising:
a first support member at least partially formed from a shape memory alloy operable to assume an activated shape and an inactivated shape, and a second support member at least partially formed from said shape memory alloy and connected to said first support member, said first support member configured to abut one side of the valve and said second support member configured to abut an opposite side of the valve, whereby a portion of the valve tissue is trapped between said first and second support members upon said shape memory alloy assuming said activated shape.
28. The device of claim 27, wherein said first and second support members are ring shaped.
29. The device of claim 27 further comprising:
a plurality of fastening elements on at least one of said first and second support members for engaging the valve tissue when the shape memory alloy is in the activated shape.
30. The device of claim 29, wherein said first support member includes at least one projection and said second support member includes at least one fastening portion to receive said projection.
31. A device for repairing a heart valve comprised of valve tissue including an annulus and a plurality of leaflets for allowing and preventing blood flow, the device comprising:
a carrier, and a coil-shaped member connected to said carrier in a removable manner, said coil-shaped member having a first support ring configured to abut one side of the valve and a second support ring configured to abut an opposite side of the valve to thereby trap a portion of the valve tissue therebetween.
32. The device of claim 31 further comprising:
a plurality of fasteners extending between said first and second support rings.
33. The device of claim 32, wherein said fasteners comprise sharp projections.
34. A replacement valve device for replacing a heart valve of a patient, the device comprising:
a first support ring, and a second support ring connected to said first support ring to form a coiled configuration, said first support ring configured to abut one side of an area of valve tissue and said second support ring configured to abut an opposite side of the area of the valve tissue to thereby trap the valve tissue therebetween, and a replacement valve coupled to said second support ring and including at least one valve element extending within said second support ring for allowing and preventing blood flow therethrough.
35. The device of claim 34, wherein said replacement valve is coupled to said second support ring in a removable manner.
36. The device of claim 35, wherein said replacement valve and said second support ring include mating engagement elements to allow coupling in the relatable manner.
37. The device of claim 35, wherein said replacement valve is threadable into said second support ring.
38. The device of claim 34, wherein said first and second support rings are contained in generally the same plane.
39. The device of claim 34, wherein said first and second support rings are contained in substantially different planes.
40. The device of claim 34, wherein said replacement valve and said second support ring include respective cuffs adapted to receive sutures applied therebetween to fasten said replacement valve to said second support ring.
41 . The device of claim 34, wherein said second support ring includes a cuff containing a movable fastening element which is engageable with said replacement valve to couple said replacement valve to said second support ring.
42. The device of claim 41, wherein said fastening element is formed from a shape memory alloy.
43. A method of repairing a heart valve comprised of valve tissue including an annulus and a plurality of leaflets for allowing and preventing blood flow, the method comprising:
inserting a first end of a coil-shaped support through a portion of the valve tissue, rotating at least a first ring of the coil-shaped support to position the first ring on a first side of the valve, and positioning at least a, second ring of the coil-shaped support on an opposite second side of the valve.
44. The method of claim 43, further comprising:
fastening the first and second rings together to trap the valve tissue therebetween.
45. The method of claim 44, wherein the step of fastening the first and second rings together further comprises:
inserting fasteners through said first and second rings and through the valve tissue disposed therebetween.
46. The method of claim 44, wherein the step of fastening the first and second rings together further comprises:
activating a plurality of sharp projections from said first ring toward said second ring and through the valve tissue disposed therebetween.
47. The method of claim 43, wherein the inserting and rotating steps each further comprise:
extending the coil shaped support from a catheter.
48. The method of claim 43, wherein said coil shaped support is coupled with a carrier during the inserting, rotating and positioning steps, and the method further comprises:
removing the carrier after the positioning step.
49. The method of claim 48, further comprising:
driving a plurality of fastening elements through the coil shaped support and valve tissue, and against the carrier prior to removing the carrier.
50. The method of claim 43, wherein said coil shaped support includes a material having a lower coefficient of friction than said outer surface, and the method further comprising:
performing at least the inserting and rotating steps with the material disposed on at least a portion of the outer surface, and removing the material after the rotating step.
51. The method of claim 50 further comprising:
removing the material after the positioning step.
52. The method of claim 43, further comprising:
adjusting the diameter of at feast one of said first and second rings to adjust the diameter of the annulus.
53. The method of claim 43, further comprising:
coupling a replacement valve to at least one of said first and second rings.
54. A method of replacing a heart valve of a patient, the method comprising:
inserting a first end of a coil-shaped support through an area of valve tissue, rotating at least a first ring of the coil-shaped support to position the first ring on a first side of the valve tissue, positioning at least a second ring of the coil-shaped support on an opposite second side of the valve tissue, and coupling a replacement valve to at least one of the first and second rings.
55. The method of claim 54, wherein the valve tissue is an annulus associated with a native heart valve.
56. The method of claim 54, wherein coupling the replacement valve further comprises suturing a cuff on the replacement valve to a cuff on one of the first and second rings.
57. The method of claim 54, wherein coupling the replacement valve further comprises rotating the replacement valve into sealing engagement with one of the first and second rings.
58. The method of claim 54, wherein coupling the replacement valve further comprises rotating a cuff on the replacement valve over one of the first and second rings.
59. The method of claim 54, wherein coupling the replacement valve further comprises activating a fastening element formed from a shape memory alloy.
CA2414022A 2000-07-06 2001-05-31 Annuloplasty devices Expired - Lifetime CA2414022C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2673614A CA2673614C (en) 2000-07-06 2001-05-31 Annuloplasty devices

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/610,784 2000-07-06
US09/610,784 US6419696B1 (en) 2000-07-06 2000-07-06 Annuloplasty devices and related heart valve repair methods
PCT/US2001/017534 WO2002003892A1 (en) 2000-07-06 2001-05-31 Annuloplasty devices

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2673614A Division CA2673614C (en) 2000-07-06 2001-05-31 Annuloplasty devices

Publications (2)

Publication Number Publication Date
CA2414022A1 true CA2414022A1 (en) 2002-01-17
CA2414022C CA2414022C (en) 2010-02-23

Family

ID=24446402

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2414022A Expired - Lifetime CA2414022C (en) 2000-07-06 2001-05-31 Annuloplasty devices
CA2673614A Expired - Lifetime CA2673614C (en) 2000-07-06 2001-05-31 Annuloplasty devices

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2673614A Expired - Lifetime CA2673614C (en) 2000-07-06 2001-05-31 Annuloplasty devices

Country Status (10)

Country Link
US (3) US6419696B1 (en)
EP (1) EP1296618B1 (en)
JP (2) JP4373672B2 (en)
CN (2) CN100496432C (en)
AT (1) ATE384494T1 (en)
AU (1) AU2001265225A1 (en)
CA (2) CA2414022C (en)
DE (1) DE60132584T2 (en)
ES (1) ES2299489T3 (en)
WO (1) WO2002003892A1 (en)

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