CA2419457A1 - Selective organ cooling apparatus and method - Google Patents

Selective organ cooling apparatus and method Download PDF

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Publication number
CA2419457A1
CA2419457A1 CA002419457A CA2419457A CA2419457A1 CA 2419457 A1 CA2419457 A1 CA 2419457A1 CA 002419457 A CA002419457 A CA 002419457A CA 2419457 A CA2419457 A CA 2419457A CA 2419457 A1 CA2419457 A1 CA 2419457A1
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CA
Canada
Prior art keywords
working fluid
blood
heat transfer
lumen
turbulence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002419457A
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French (fr)
Other versions
CA2419457C (en
Inventor
John D. Dobak, Iii
Juan C. Lasheras
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innercool Therapies Inc
Original Assignee
Innercool Therapies, Inc.
John D. Dobak, Iii
Juan C. Lasheras
Del Mar Medical Technologies, Inc.
Neurothermia, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/103,342 external-priority patent/US6096068A/en
Application filed by Innercool Therapies, Inc., John D. Dobak, Iii, Juan C. Lasheras, Del Mar Medical Technologies, Inc., Neurothermia, Inc. filed Critical Innercool Therapies, Inc.
Publication of CA2419457A1 publication Critical patent/CA2419457A1/en
Application granted granted Critical
Publication of CA2419457C publication Critical patent/CA2419457C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
    • A61B2018/0022—Balloons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0212—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0231—Characteristics of handpieces or probes
    • A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
    • A61F2007/0056—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels

Abstract

A catheter system and method are provided which change the temperature of a fluid, such as blood, by heat transfer. Selective cooling or heating of an organ may be performed by changing the temperature of the blood feeding the organ. The catheter system includes an inlet lumen and an outlet lumen structured and arranged to carry a working fluid having a temperature different from the adjacent blood. The outlet lumen is configured to induce turbulence in the adjacent fluid passing adjacent the outlet lumen.

Claims (96)

1. A catheter method of changing the temperature of blood by heat transfer to or from a circulating working fluid, comprising:
inserting an inflatable heat transfer element formed by at least an inlet lumen and an inflatable outlet lumen into an artery or vein;
inflating the inflatable heat transfer element by delivering a circulating working fluid to the inlet lumen of the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood such that blood contacts both the inlet lumen and the outlet lumen; and inducing turbulence in the working fluid by passing the working fluid through a helical turbulence-inducing path formed by the outlet lumen when inflated, and inducing turbulence in blood flowing past the helical turbulence inducing path formed by the outlet lumen when inflated thereby enhancing heat transfer between the circulating working fluid and the blood.
2. A catheter method of changing the temperature of blood by heat transfer to or from a circulating working fluid, comprising:
inserting an inflatable heat transfer element formed by at least an inlet lumen and an inflatable outlet lumen into a flow of blood in an artery or vein; and inflating the inflatable heat transfer element by delivering a working fluid having a temperature different than the blood temperature to an interior of the inlet lumen of the inflatable heat transfer element, the outlet lumen of the inflatable heat transfer element having a helical or spiral turbulence-inducing shape when inflated, blood such that blood contacts both the inlet lumen and the outlet lumen, and such that turbulence is induced in a substantial portion of a free stream of blood by contact with both the helical or spiral turbulence-inducing shape of the outlet lumen and the inlet lumen.
3. The method of claim 1, further comprising delivering the working fluid at a temperature of between about -3°C and 36°C.
4. The method of claim 1, further comprising delivering the working fluid at a pressure of less than about 5 atmospheres.
5. The method of claim 4, further comprising delivering the working fluid at a pressure of between about 1 and 5 atmospheres.
6. The method of claim 1, further comprising absorbing more than about 75 watts of heat from the blood.
7. The method of claim 1, further comprising inducing blood turbulence with a turbulence intensity greater than about 0.05 within the carotid artery.
8. The method of claim 1, further comprising delivering the working fluid at a temperature of greater than about 37°C.
9. The method of claim 1, further comprising inducing blood turbulence in greater than 20% of the period of the cardiac cycle within the carotid artery.
10. The method of claim 9, further comprising inducing blood turbulence throughout the period of the cardiac cycle within the carotid artery.
11. A method of changing the temperature of blood, comprising:
providing an inflatable heat transfer element, the inflatable heat transfer element formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a turbulence-inducing shape;
inserting the inflatable heat transfer element into a blood vessel;

delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and returning the working fluid to the working fluid supply via the outlet lumen.
12. The method of claim 11, wherein the method is a method of heating, and the temperature of the circulating working fluid is greater than about 37°C.
13. The method of claim 11, wherein the method is a method of cooling, and the temperature of the circulating working fluid is between about -3°C and 36°C.
14. A method of changing the temperature of blood, comprising:
providing an inflatable heat transfer element having a turbulence-enhancing shape such that the inflatable heat transfer element is formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a shape of a helix;
inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and returning the working fluid to the working fluid supply via the outlet lumen.
15. A method of changing the temperature of blood, comprising:
providing an inflatable heat transfer element having a turbulence-enhancing shape such that the inflatable heat transfer element is formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a shape of a spiral;
inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heal transfer between the circulating working fluid and the blood; and returning the working fluid to the working fluid supply via the outlet lumen.
16. A method of changing the temperature of blood, comprising:
providing an inflatable heat transfer element, the inflatable heat transfer element formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a turbulence-enhancing shape such that one lumen helically encircles the other;
inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and returning the working fluid to the working fluid supply via the outlet lumen.
17. The method of claim 16, wherein the turbulence-inducing shape is sufficient to cause a turbulence intensity of at least about 0.05.
18. The method of claim 16, wherein the turbulence-inducing shape is sufficient to cause turbulence characterized by a Nusselt number of at least about 5.
19. The method of claim 16, further comprising disposing the heat transfer element in an artery.
20. The method of claim 19, wherein the artery is the carotid artery.
21. The method of claim 19, wherein the artery is the femoral artery.
22. The method of claim 16, further comprising disposing the heat transfer element in a vein.
23. The method of claim 22, wherein the vein is the femoral vein.
24. The method of claim 22, wherein the vein is the IVC.
25. The method of claim 16, further comprising inducing turbulence in the free stream of the blood flow.
26. The method of claim 16, wherein the outlet lumen is the lumen with a turbulence-inducing shape, and further comprising delivering the circulating working fluid to multiple outlet lumens.
27. The method of claim 26, wherein each outlet lumen has a turbulence-enhancing shape.
28. The method of claim 27, wherein each outlet lumen has the shape of a helix.
29. The method of claim 27, wherein each outlet lumen has the shape of a spiral.
30. The method of claim 27, wherein each outlet lumen helically encircles the inlet lumen.
31. The method of claim 27, wherein each outlet lumen has the shape of a spiral.
32. A method of changing the temperature of blood, comprising:
providing an inflatable heat transfer element having a longitudinal axis, the inflatable heat transfer element formed by at least an inlet lumen and an outlet lumen, the inlet and outlet lumens at least partially coaxial, at least one of the inlet lumen or the outlet lumen having a turbulence-enhancing shape such that the radius of the inlet or outlet lumen varies with respect to position along the axis;

inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and returning the working fluid to the working fluid supply via the outlet lumen.
33. A method of changing the temperature of blood, comprising:
providing an inflatable heat transfer element, the inflatable heat transfer element formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a turbulence-inducing shape and configured to cause two counter-rotating flows to develop in the circulating working fluid;

inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and returning the working fluid to the working fluid supply via the outlet lumen.
34. A catheter method of changing the temperature of blood by heat transfer, comprising:

inserting a heat transfer element formed by at least an inlet lumen and an inflatable outlet lumen into an artery or vein;
delivering a circulating working fluid to the heat transfer element, the temperature of the working fluid different from that of the blood; and passing the circulating working fluid through a helical path formed by the outlet lumen, such that the helical return path enhances the heat transfer between the working fluid and the blood by causing turbulence therein.
35. The method of claim 34, further comprising delivering the circulating working fluid at a temperature of between about -3°C and 36°C.
36. The method of claim 34, further comprising delivering the working fluid at a pressure of less than about 5 atmospheres.
37. The method of claim 34, further comprising absorbing more than about 75 watts of heat froth the blood.
38. The method of claim 34, further comprising inducing blood turbulence with a turbulence intensity greater than about 0.05 within the artery or vein.
39. The method of claim 34, wherein the inlet lumen and the outlet lumen are made of a flexible material.
40. The method of claim 35, wherein the flexible material is rubber.
41. The method of claim 35, wherein the flexible material is a material capable of undergoing inflation.
42. The method of claim 34, further comprising more than one helical path.
43. The method of claim 34, wherein the working fluid is saline.
44. The method of claim 34, wherein the helical shape of the outlet lumen is tapered when inflated.
45. The method of claim 40, wherein the helical path is segmentally tapered when inflated.
46. The method of claim 34, wherein a longitudinal length of the helical path is between about 5 and 30 centimeters.
47. The method of claim 34, wherein a diameter of the helical path is less than about 8 millimeters when inflated.
48. The method of claim 40, wherein the outer diameter of the helical path when inflated, is between about 2 millimeters and 8 millimeters and tapers to less than 2 millimeters.
49. The method of claim 45, wherein a length of a segment is between about 1 centimeter and 10 centimeters.
50. The method of claim 34, further comprising a working fluid supply including a pump, and wherein the pump circulates the working fluid.
51. The method of claim 50, wherein the working fluid supply is configured to produce a pressurized working fluid at a temperature of between about -3°C and 36°C and at a pressure below about 5 atmospheres of pressure.
52. The method of claim 34, wherein the helical path includes a surface coating or treatment to inhibit clot formation.
53. The method of claim 52, wherein the surface coating or treatment includes heparin.
54. The method of claim 34, wherein the working fluid is an aqueous solution.
55. The method of claim 34, wherein the helical path is structured and shaped to have a geometry so as to induce turbulence within a free stream of blood flow when disposed in an artery.
56. The method of claim 34, wherein the helical path is structured and shaped to have a geometry so as to induce turbulence within a free stream of blood flow to a turbulence intensity of greater than about 0.05.
57. The method of claim 34, wherein the helical path is structured and shaped to have a geometry so as to cause a turbulence within a free stream of blood flow characterized by a Nusselt number of at least about 5.
58 58. The method of claim 34, wherein the helical path is structured and shaped to have a geometry so as to induce turbulence within a free stream of blood flow when disposed in a vein.
59. The method of claim 55, wherein the artery is a carotid artery.
60. The method of claim 55, wherein the artery is a femoral artery.
61. The method of claim 58, wherein the vein is a jugular vein.
62. The method of claim 58, wherein the vein is a femoral vein.
63. The method of claim 58, wherein the vein is the inferior vena cava.
64. The method of claim 34, wherein the inlet lumen is substantially straight.
65. The method of claim 34, wherein the outlet lumen helically encircles the inlet lumen.
66. The method of claim 34, wherein the helical path is such that the outlet lumen helically encircles the inlet lumen.
67. The method of claim 66, further comprising more than one helical path, each helical path encircling an inlet lumen.
68. The method of claim 67, wherein the inlet lumen is substantially straight.
69. The method of claim 68, wherein the inlet lumen is segmentally tapered.
70. The method of claim 66, wherein the structure of the helical path is structured and configured to have a geometry such that the induced turbulence is characterized by a Nusselt number of at least about 5.
71. An intravascular catheter system to change the temperature of blood by heat transfer to or from a circulating working fluid, comprising:
an inlet lumen; and an outlet lumen, the inlet and outlet lumens formed of a flexible material, the outlet lumen coupled to the inlet lumen so as to transfer the circulating working fluid between the two, the outlet lumen having a helical or a spiral structure, wherein the circulating working fluid is not exposed to the blood.
72. The catheter system of claim 71, wherein the inlet lumen and the outlet lumen are made of a flexible polymer material.
73. The catheter system of claim 72, wherein the flexible polymer material is rubber.
74. The catheter system of claim 72, wherein the flexible polymer material is a material capable of undergoing inflation.
75. The catheter system of claim 71, further comprising more than one outlet lumen, each outlet lumen having a helical or spiral shape.
76. The catheter system of claim 71, wherein the circulating working fluid is saline.
77. The catheter system of claim 71, further comprising a wire disposed within one of at least the inlet lumen or the outlet lumen.
78. The catheter system of claim 71, wherein a length of the inlet lumen is between about 5 and 30 centimeters.
79. The catheter system of claim 71, further comprising a working fluid supply including a pump, and wherein the pump circulates the working fluid.
80. The catheter system of claim 79, wherein the working fluid supply is configured to produce a pressurized working fluid at a temperature of between about -3°C and 36°C and at a pressure below about 5 atmospheres of pressure.
81. The catheter system of claim 71, wherein the outlet lumen includes a surface coating or treatment to inhibit clot formation.
82. The catheter system of claim 81, wherein the surface coating or treatment includes heparin.
83. The catheter system of claim 71, wherein the inlet lumen is substantially straight.
84. The catheter system of claim 71, wherein the outlet lumen helically encircles the inlet lumen.
85. The catheter system of claim 75, wherein each outlet lumen helically encircles the inlet lumen.
86. A method for selectively cooling or heating an organ in a body of a patient, comprising:
introducing a catheter having an inflatable heat transfer element into an artery supplying the organ, the heat transfer element having a lumen with a helical shape to induce turbulence in blood flowing in the artery;
inflating the heat transfer element; and inducing free stream turbulence in blood flowing over the heat transfer element;
such that heat is removed from or added to the blood to cool or heat the organ.
87. A method for selectively cooling an organ in a body of a patient, comprising:
introducing a catheter having a heat transfer element into a blood vessel supplying the organ;
circulating a working fluid through the heat transfer element, the working fluid having a temperature less than the temperature of the blood in the blood vessel; and inducing free stream turbulence in blood flowing over the heat transfer element;
such that heat is removed from the blood to cool the organ.
88. A catheter method of inducing a therapeutic state of hypothermia in a patient, comprising:

inserting an inflatable heat transfer element into an artery or vein;
inflating the inflatable heat transfer element by delivering a circulating working fluid to the inflatable heat transfer element, the temperature of the circulating working fluid lower than that of the blood; and inducing turbulence in the working fluid or in the blood by passing the working fluid through a helical turbulence-inducing path, thereby enhancing heat transfer between the circulating working fluid and the blood.
89. The method of claim 88, wherein the temperature of the working fluid is between about -3°C and 36°C.
90. A catheter method of rewarming a patient, comprising:
inserting an inflatable heat transfer element into an artery or vein;
inflating the inflatable heat transfer element by delivering a circulating working fluid to the inflatable heat transfer element, the temperature of the circulating working fluid higher than that of the blood; and inducing turbulence in the working fluid or in the blood by passing the working fluid through a helical turbulence-inducing path, thereby enhancing heat transfer between the circulating working fluid and the blood.
91. The method of claim 90, wherein the temperature of the working fluid is greater than about 37°C.
92. A method for selectively warming an organ in a body of a patient, comprising:
introducing a catheter having a heat transfer element into a blood vessel supplying the organ;

circulating a working fluid through the heat transfer element, the working fluid having a temperature greater than the temperature of the blood in the blood vessel; and inducing free stream turbulence in blood flowing over the heat transfer element;
such that heat is added from the blood to warm the organ.
93. Use of the catheter system of any one of claims 71-85 for changing the temperature of blood.
94. Use of the catheter system of any one of claims 71-85 for selectively cooling or heating an organ in a body of a patient in need of such therapy.
95. Use of the catheter system of any one of claims 71-85 for inducing a therapeutic state of hypothermia in a patient in need of such therapy.
96. Use of the catheter system of any one of claims 71-85 for rewarming a patient in need of such therapy.
CA002419457A 1998-06-23 1999-06-15 Selective organ cooling apparatus and method Expired - Lifetime CA2419457C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/103,342 US6096068A (en) 1998-01-23 1998-06-23 Selective organ cooling catheter and method of using the same
US09/215,038 US6261312B1 (en) 1998-06-23 1998-12-16 Inflatable catheter for selective organ heating and cooling and method of using the same
US09/103,342 1999-02-09
US09/215,038 1999-02-09
CA002335997A CA2335997C (en) 1998-06-23 1999-06-15 Selective organ cooling apparatus and method

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002335997A Division CA2335997C (en) 1998-06-23 1999-06-15 Selective organ cooling apparatus and method

Publications (2)

Publication Number Publication Date
CA2419457A1 true CA2419457A1 (en) 1999-12-29
CA2419457C CA2419457C (en) 2010-03-09

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CA002419457A Expired - Lifetime CA2419457C (en) 1998-06-23 1999-06-15 Selective organ cooling apparatus and method

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US (7) US6261312B1 (en)
EP (1) EP1089780B1 (en)
JP (4) JP3479706B2 (en)
AU (3) AU756941B2 (en)
CA (2) CA2335997C (en)
DE (1) DE1089780T1 (en)
WO (1) WO1999066970A1 (en)

Families Citing this family (203)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6623516B2 (en) * 1992-08-13 2003-09-23 Mark A. Saab Method for changing the temperature of a selected body region
US6325818B1 (en) * 1999-10-07 2001-12-04 Innercool Therapies, Inc. Inflatable cooling apparatus for selective organ hypothermia
US6251130B1 (en) 1998-03-24 2001-06-26 Innercool Therapies, Inc. Device for applications of selective organ cooling
US6096068A (en) 1998-01-23 2000-08-01 Innercool Therapies, Inc. Selective organ cooling catheter and method of using the same
US7371254B2 (en) 1998-01-23 2008-05-13 Innercool Therapies, Inc. Medical procedure
US6383210B1 (en) 2000-06-02 2002-05-07 Innercool Therapies, Inc. Method for determining the effective thermal mass of a body or organ using cooling catheter
US6312452B1 (en) 1998-01-23 2001-11-06 Innercool Therapies, Inc. Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device
US6702841B2 (en) 1998-01-23 2004-03-09 Innercool Therapies, Inc. Method of manufacturing a heat transfer element for in vivo cooling
US6231595B1 (en) 1998-03-31 2001-05-15 Innercool Therapies, Inc. Circulating fluid hypothermia method and apparatus
US6261312B1 (en) 1998-06-23 2001-07-17 Innercool Therapies, Inc. Inflatable catheter for selective organ heating and cooling and method of using the same
US6491039B1 (en) 1998-01-23 2002-12-10 Innercool Therapies, Inc. Medical procedure
US6719779B2 (en) 2000-11-07 2004-04-13 Innercool Therapies, Inc. Circulation set for temperature-controlled catheter and method of using the same
US6464716B1 (en) 1998-01-23 2002-10-15 Innercool Therapies, Inc. Selective organ cooling apparatus and method
US7458984B2 (en) * 1998-01-23 2008-12-02 Innercool Therapies, Inc. System and method for inducing hypothermia with active patient temperature control employing catheter-mounted temperature sensor and temperature projection algorithm
US6843800B1 (en) * 1998-01-23 2005-01-18 Innercool Therapies, Inc. Patient temperature regulation method and apparatus
US6364899B1 (en) 1998-01-23 2002-04-02 Innercool Therapies, Inc. Heat pipe nerve cooler
US6379378B1 (en) * 2000-03-03 2002-04-30 Innercool Therapies, Inc. Lumen design for catheter
US6585752B2 (en) * 1998-06-23 2003-07-01 Innercool Therapies, Inc. Fever regulation method and apparatus
US6551349B2 (en) 1998-03-24 2003-04-22 Innercool Therapies, Inc. Selective organ cooling apparatus
US6576002B2 (en) 1998-03-24 2003-06-10 Innercool Therapies, Inc. Isolated selective organ cooling method and apparatus
US6599312B2 (en) 1998-03-24 2003-07-29 Innercool Therapies, Inc. Isolated selective organ cooling apparatus
US6685732B2 (en) 1998-03-31 2004-02-03 Innercool Therapies, Inc. Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing microporous balloon
US6905494B2 (en) 1998-03-31 2005-06-14 Innercool Therapies, Inc. Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection
US7001378B2 (en) * 1998-03-31 2006-02-21 Innercool Therapies, Inc. Method and device for performing cooling or cryo-therapies, for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection
US6602276B2 (en) 1998-03-31 2003-08-05 Innercool Therapies, Inc. Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation
US7291144B2 (en) 1998-03-31 2007-11-06 Innercool Therapies, Inc. Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation
US6520933B1 (en) * 1998-04-21 2003-02-18 Alsius Corporation Central venous line cooling catheter having a spiral-shaped heat exchange member
US8128595B2 (en) 1998-04-21 2012-03-06 Zoll Circulation, Inc. Method for a central venous line catheter having a temperature control system
US6589271B1 (en) 1998-04-21 2003-07-08 Alsius Corporations Indwelling heat exchange catheter
US6530946B1 (en) 1998-04-21 2003-03-11 Alsius Corporation Indwelling heat exchange heat pipe catheter and method of using same
US7255709B2 (en) * 1998-04-21 2007-08-14 Alsius Corporation Intravascular heat exchange catheter with temperature sensor
US6338727B1 (en) 1998-08-13 2002-01-15 Alsius Corporation Indwelling heat exchange catheter and method of using same
US6610083B2 (en) 1998-08-24 2003-08-26 Radiant Medical, Inc. Multiple lumen heat exchange catheters
US6620189B1 (en) 2000-02-28 2003-09-16 Radiant Medical, Inc. Method and system for control of a patient's body temperature by way of a transluminally insertable heat exchange catheter
US6428563B1 (en) 2000-01-21 2002-08-06 Radiant Medical, Inc. Heat exchange catheter with improved insulated region
US6673098B1 (en) * 1998-08-24 2004-01-06 Radiant Medical, Inc. Disposable cassette for intravascular heat exchange catheter
GB9828696D0 (en) * 1998-12-29 1999-02-17 Houston J G Blood-flow tubing
EP1158941B1 (en) 1999-01-04 2005-10-12 Medivance, Inc. Improved cooling/heating pad and system
US6830581B2 (en) 1999-02-09 2004-12-14 Innercool Therspies, Inc. Method and device for patient temperature control employing optimized rewarming
WO2001043661A2 (en) * 1999-12-14 2001-06-21 Radiant Medical, Inc. Method for reducing myocardial infarct by applicaton of intravascular hypothermia
WO2001058397A1 (en) * 2000-02-09 2001-08-16 Radiant Medical, Inc. Multiple lumen heat exchange catheters
US6648906B2 (en) 2000-04-06 2003-11-18 Innercool Therapies, Inc. Method and apparatus for regulating patient temperature by irrigating the bladder with a fluid
US7374532B2 (en) 2000-04-14 2008-05-20 Attenuex Technologies, Inc. High vapor pressure attenuation device
US6682473B1 (en) 2000-04-14 2004-01-27 Solace Therapeutics, Inc. Devices and methods for attenuation of pressure waves in the body
US8574146B2 (en) 2000-04-14 2013-11-05 Attenuex Technologies, Inc. Implant with high vapor pressure medium
US10327880B2 (en) 2000-04-14 2019-06-25 Attenuex Technologies, Inc. Attenuation device for use in an anatomical structure
US6482169B1 (en) * 2000-06-08 2002-11-19 William G. Kuhle Double-lumen catheter
US6726708B2 (en) 2000-06-14 2004-04-27 Innercool Therapies, Inc. Therapeutic heating and cooling via temperature management of a colon-inserted balloon
US6958075B2 (en) * 2001-09-18 2005-10-25 Celsion Corporation Device and method for treatment of tissue adjacent a bodily conduit by thermocompression
US7837720B2 (en) * 2000-06-20 2010-11-23 Boston Scientific Corporation Apparatus for treatment of tissue adjacent a bodily conduit with a gene or drug-coated compression balloon
WO2002026307A1 (en) * 2000-09-28 2002-04-04 Alsius Corporation Central venous line catheter and method of preparing the same for the use
US6660026B2 (en) * 2000-10-05 2003-12-09 Seacoast Technologies, Inc. Multi-tipped cooling probe
CA2729122C (en) 2000-11-07 2015-01-13 Innercool Therapies, Inc. Fever regulation method and apparatus
US6719723B2 (en) * 2000-12-06 2004-04-13 Innercool Therapies, Inc. Multipurpose catheter assembly
WO2002058606A1 (en) * 2001-01-24 2002-08-01 Alsius Corporation Central venous catheter with heat exchange properties
US6450987B1 (en) 2001-02-01 2002-09-17 Innercool Therapies, Inc. Collapsible guidewire lumen
US6451045B1 (en) * 2001-02-22 2002-09-17 Alsius Corporation Heat exchange catheter having a helically wrapped heat exchanger
US6709448B2 (en) 2001-04-13 2004-03-23 Alsius Corporation Open core heat exchange catheter, system and method
US6641603B2 (en) 2001-04-13 2003-11-04 Alsius Corporation Heat exchange catheter having helically wound reinforcement
US6641602B2 (en) 2001-04-13 2003-11-04 Alsius Corporation Method and device including a colo-rectal heat exchanger
US6752786B2 (en) * 2001-05-31 2004-06-22 Radiant Medical, Inc. Moving heat exchange catheter system
US6706060B2 (en) * 2001-06-05 2004-03-16 Alsius Corporation Heat exchange catheter
US7150737B2 (en) * 2001-07-13 2006-12-19 Sci/Med Life Systems, Inc. Methods and apparatuses for navigating the subarachnoid space
CA2461217A1 (en) * 2001-09-27 2003-04-03 Roni Zvuloni Cryoplasty apparatus and method
JP2005503227A (en) * 2001-09-27 2005-02-03 ガリル メディカル リミテッド Apparatus and method for cryosurgical treatment of breast tumors
US6660027B2 (en) 2001-10-11 2003-12-09 Medivance Incorporated Patient temperature control system with fluid preconditioning
US6699267B2 (en) 2001-10-11 2004-03-02 Medivance Incorporated Patient temperature control system with fluid temperature response
US6818012B2 (en) 2001-10-11 2004-11-16 Medivance, Incorporated Patient temperature control system with fluid temperature response
CA2463021A1 (en) 2001-10-12 2003-04-24 Applied Medical Resources Corporation High-flow low-pressure irrigation system
US6800068B1 (en) * 2001-10-26 2004-10-05 Radiant Medical, Inc. Intra-aortic balloon counterpulsation with concurrent hypothermia
WO2003053496A2 (en) * 2001-12-19 2003-07-03 Ran Yaron Miniature refrigeration system for cryothermal ablation catheter
CN1646066A (en) * 2002-02-15 2005-07-27 效思因公司 Method and apparatus treating tissue adjacent a bodily conduit with thermocompression and drugs
US7464781B2 (en) * 2002-02-22 2008-12-16 Bombardier Recreational Product Inc. Three-wheeled vehicle having a split radiator and an interior storage compartment
US20030163190A1 (en) * 2002-02-25 2003-08-28 Scimed Life Systems, Inc. High temperature stent delivery system
US6692518B2 (en) 2002-02-27 2004-02-17 Medivance Incorporated Patient temperature control system
US7288109B2 (en) 2002-04-04 2007-10-30 Innercool Therapies. Inc. Method of manufacturing a heat transfer element for in vivo cooling without undercuts
JP4474590B2 (en) 2002-06-17 2010-06-09 厚夫 森 Local cooling catheter and local cooling device using the same
US20040024392A1 (en) * 2002-08-05 2004-02-05 Lewis James D. Apparatus and method for cryosurgery
US6796995B2 (en) * 2002-08-30 2004-09-28 Alsius Corporation Intravascular temperature control catheter
EP1575415B1 (en) 2002-09-12 2019-02-20 Zoll Circulation, Inc. System for determining and controlling core body temperature
CA2411569A1 (en) * 2002-11-12 2004-05-12 Ross E. Mantle Medical device for the extravascular recirculation of fluid in body cavities at controlled temperature and pressure
US7393339B2 (en) 2003-02-21 2008-07-01 C. R. Bard, Inc. Multi-lumen catheter with separate distal tips
US7300453B2 (en) * 2003-02-24 2007-11-27 Innercool Therapies, Inc. System and method for inducing hypothermia with control and determination of catheter pressure
US7938828B2 (en) * 2003-03-28 2011-05-10 Boston Scientific Scimed, Inc. Cooled ablation catheter
US7118591B2 (en) * 2003-04-17 2006-10-10 The University Of Chicago Heat transfer probe
US20040243095A1 (en) 2003-05-27 2004-12-02 Shekhar Nimkar Methods and apparatus for inserting multi-lumen spit-tip catheters into a blood vessel
US20040267338A1 (en) * 2003-06-25 2004-12-30 Kent Harrison Targeted tissue cooling within a body
US7081113B2 (en) * 2003-06-26 2006-07-25 Depuy Acromed, Inc. Helical probe
US7326195B2 (en) * 2003-11-18 2008-02-05 Boston Scientific Scimed, Inc. Targeted cooling of tissue within a body
US9011329B2 (en) 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US8024036B2 (en) 2007-03-19 2011-09-20 The Invention Science Fund I, Llc Lumen-traveling biological interface device and method of use
US7998060B2 (en) 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling delivery device
US8000784B2 (en) 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling device
US8337482B2 (en) 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
US7850676B2 (en) 2004-04-19 2010-12-14 The Invention Science Fund I, Llc System with a reservoir for perfusion management
US8092549B2 (en) 2004-09-24 2012-01-10 The Invention Science Fund I, Llc Ciliated stent-like-system
US8361013B2 (en) 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
US9801527B2 (en) 2004-04-19 2017-10-31 Gearbox, Llc Lumen-traveling biological interface device
US8353896B2 (en) 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US7288088B2 (en) * 2004-05-10 2007-10-30 Boston Scientific Scimed, Inc. Clamp based low temperature lesion formation apparatus, systems and methods
US7582083B2 (en) 2004-05-10 2009-09-01 Boston Scientific Scimed, Inc. Probe based low temperature lesion formation apparatus, systems and methods
US7291142B2 (en) 2004-05-10 2007-11-06 Boston Scientific Scimed, Inc. Low temperature lesion formation apparatus, systems and methods
US20060036302A1 (en) * 2004-05-28 2006-02-16 Kasza Kenneth E Methods of inducing protective hypothermia of organs
GB0412167D0 (en) * 2004-06-01 2004-06-30 Leuven K U Res & Dev Adhesion formation
US8992454B2 (en) * 2004-06-09 2015-03-31 Bard Access Systems, Inc. Splitable tip catheter with bioresorbable adhesive
US20060025755A1 (en) * 2004-07-30 2006-02-02 Jaime Landman Surgical cooling system and method
US20060025840A1 (en) * 2004-08-02 2006-02-02 Martin Willard Cooling tissue inside the body
US20060064146A1 (en) * 2004-09-17 2006-03-23 Collins Kenneth A Heating/cooling system for indwelling heat exchange catheter
US7824416B2 (en) * 2004-10-06 2010-11-02 Boston Scientific Scimed, Inc. Medical retrieval device
US8672988B2 (en) * 2004-10-22 2014-03-18 Medtronic Cryocath Lp Method and device for local cooling within an organ using an intravascular device
US20060161232A1 (en) * 2005-01-18 2006-07-20 Kasza, Oras and Son to The University of Chicago Phase-change particulate ice slurry coolant medical delivery tubing and insertion devices
US8491644B1 (en) 2005-02-22 2013-07-23 Medivance Incorporated Portable, refrigerant-based apparatus and method for rapid systemic patient cooling
US20060190066A1 (en) * 2005-02-23 2006-08-24 Worthen William J System and method for bringing hypothermia rapidly onboard
US7070612B1 (en) 2005-02-23 2006-07-04 Alsius Corporation System and method for bringing hypothermia rapidly onboard
US20060190062A1 (en) * 2005-02-23 2006-08-24 Worthen William J System and method for reducing shivering when using external cooling pads
US7425216B2 (en) * 2005-03-01 2008-09-16 Alsius Corporation System and method for treating cardiac arrest and myocardial infarction
US7892269B2 (en) * 2005-04-18 2011-02-22 Zoll Circulation, Inc. External heat exchange pad for patient
EP2305188B1 (en) 2005-04-27 2015-06-03 ZOLL Circulation, Inc. Apparatus for providing enhanced heat transfer from a body
US20060276864A1 (en) * 2005-06-03 2006-12-07 Alsius Corporation Systems and methods for sensing patient temperature in temperature management system
US20060293732A1 (en) * 2005-06-27 2006-12-28 Collins Kenneth A Thermoelectric cooler (TEC) heat exchanger for intravascular heat exchange catheter
US7181927B2 (en) 2005-07-01 2007-02-27 Alsius Corporation Primary heat exchanger for patient temperature control
US7951182B2 (en) * 2005-07-14 2011-05-31 Zoll Circulation, Inc. System and method for leak detection in external cooling pad
US7389653B2 (en) * 2005-09-15 2008-06-24 The University Of Chicago Medical ice slurry production device
WO2007038476A2 (en) 2005-09-26 2007-04-05 Atteneux Technologies, Inc. Pressure attenuation device
AU2006333457B2 (en) * 2005-12-22 2013-05-02 Hybernia Medical Llc Systems and methods for intravascular cooling
US20070225781A1 (en) * 2006-03-21 2007-09-27 Nidus Medical, Llc Apparatus and methods for altering temperature in a region within the body
US9198563B2 (en) 2006-04-12 2015-12-01 The Invention Science Fund I, Llc Temporal control of a lumen traveling device in a body tube tree
EP2018129B1 (en) 2006-05-12 2020-04-01 Vytronus, Inc. Device for ablating body tissue
US7822485B2 (en) 2006-09-25 2010-10-26 Zoll Circulation, Inc. Method and apparatus for spinal cooling
US7867266B2 (en) 2006-11-13 2011-01-11 Zoll Circulation, Inc. Temperature management system with assist mode for use with heart-lung machine
US7892270B2 (en) * 2006-11-21 2011-02-22 Zoll Circulation Inc. Temperature management system and method for burn patients
US8353893B2 (en) * 2007-03-07 2013-01-15 Zoll Circulation, Inc. System and method for rapidly cooling cardiac arrest patient
EP2155300A1 (en) 2007-04-05 2010-02-24 Velomedix, Inc Automated therapy system and method
WO2008124643A1 (en) * 2007-04-05 2008-10-16 Velomedix, Inc. Device and method for safe access to a body cavity
US9737692B2 (en) 2007-05-18 2017-08-22 Zoll Circulation, Inc. System and method for effecting non-standard fluid line connections
US9364586B2 (en) 2007-05-31 2016-06-14 Abbott Cardiovascular Systems Inc. Method and apparatus for improving delivery of an agent to a kidney
US9144509B2 (en) 2007-05-31 2015-09-29 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
US8216209B2 (en) 2007-05-31 2012-07-10 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
US9149610B2 (en) 2007-05-31 2015-10-06 Abbott Cardiovascular Systems Inc. Method and apparatus for improving delivery of an agent to a kidney
CA2693774A1 (en) 2007-07-09 2009-01-15 Velomedix, Inc. Hypothermia devices and methods
CN101918066B (en) 2007-10-17 2013-07-31 巴德阿克塞斯系统股份有限公司 Manufacture of split tip catheters and the split tip catheters
US8066660B2 (en) 2007-10-26 2011-11-29 C. R. Bard, Inc. Split-tip catheter including lateral distal openings
US8292841B2 (en) 2007-10-26 2012-10-23 C. R. Bard, Inc. Solid-body catheter including lateral distal openings
US8092415B2 (en) 2007-11-01 2012-01-10 C. R. Bard, Inc. Catheter assembly including triple lumen tip
US9579485B2 (en) 2007-11-01 2017-02-28 C. R. Bard, Inc. Catheter assembly including a multi-lumen configuration
JP5181791B2 (en) * 2008-04-03 2013-04-10 ソニー株式会社 Voltage controlled variable frequency oscillation circuit and signal processing circuit
US20100152582A1 (en) * 2008-06-13 2010-06-17 Vytronus, Inc. Handheld system and method for delivering energy to tissue
US9155588B2 (en) 2008-06-13 2015-10-13 Vytronus, Inc. System and method for positioning an elongate member with respect to an anatomical structure
CA2726934C (en) * 2008-06-14 2018-04-24 Vytronus, Inc. System and method for delivering energy to tissue
US10363057B2 (en) 2008-07-18 2019-07-30 Vytronus, Inc. System and method for delivering energy to tissue
US20100049099A1 (en) * 2008-07-18 2010-02-25 Vytronus, Inc. Method and system for positioning an energy source
US8845627B2 (en) 2008-08-22 2014-09-30 Boston Scientific Scimed, Inc. Regulating pressure to lower temperature in a cryotherapy balloon catheter
US9220924B2 (en) 2008-10-30 2015-12-29 Vytronus, Inc. System and method for energy delivery to tissue while monitoring position, lesion depth, and wall motion
US8414508B2 (en) 2008-10-30 2013-04-09 Vytronus, Inc. System and method for delivery of energy to tissue while compensating for collateral tissue
US11298568B2 (en) 2008-10-30 2022-04-12 Auris Health, Inc. System and method for energy delivery to tissue while monitoring position, lesion depth, and wall motion
US9033885B2 (en) * 2008-10-30 2015-05-19 Vytronus, Inc. System and method for energy delivery to tissue while monitoring position, lesion depth, and wall motion
US9192789B2 (en) 2008-10-30 2015-11-24 Vytronus, Inc. System and method for anatomical mapping of tissue and planning ablation paths therein
AU2009313320A1 (en) * 2008-11-07 2010-05-14 Velomedix, Inc. Devices and methods for monitoring core temperature and an intraperitoneal parameter
CA2742787C (en) 2008-11-17 2018-05-15 Vytronus, Inc. Systems and methods for ablating body tissue
US8475379B2 (en) * 2008-11-17 2013-07-02 Vytronus, Inc. Systems and methods for ablating body tissue
EP2393460A4 (en) * 2009-02-06 2012-06-27 Velomedix Inc Method and apparatus for inducing therapeutic hypothermia
US8892185B2 (en) * 2009-06-26 2014-11-18 Cianna Medical, Inc. Apparatus, systems, and methods for localizing markers or tissue structures within a body
US9386942B2 (en) 2009-06-26 2016-07-12 Cianna Medical, Inc. Apparatus, systems, and methods for localizing markers or tissue structures within a body
WO2012006625A2 (en) 2010-07-09 2012-01-12 Velomedix, Inc. Method and apparatus for pressure measurement
WO2012107076A1 (en) * 2011-02-07 2012-08-16 Cermavein Device and method for injecting pulsed steam into a human or animal vessel e.g. a vein
US20120283722A1 (en) * 2011-05-02 2012-11-08 Medtronic Ablation Frontiers Llc Adiabatic cooling system for medical devices
EP2736581A4 (en) 2011-07-25 2015-11-04 Neurosave Inc Non-invasive systems, devices, and methods for selective brain cooling
US9554822B2 (en) * 2011-09-02 2017-01-31 Abbott Cardiovascular Systems Inc. Thrombectomy catheter with aspiration and guidewire lumens defining an asymmetrical taper and cutting edge with offset tip
US9259348B2 (en) * 2011-09-28 2016-02-16 Zoll Circulation, Inc. Transatrial patient temperature control catheter
US10045881B2 (en) * 2011-09-28 2018-08-14 Zoll Circulation, Inc. Patient temperature control catheter with helical heat exchange paths
US9314370B2 (en) 2011-09-28 2016-04-19 Zoll Circulation, Inc. Self-centering patient temperature control catheter
US9662243B2 (en) 2011-09-30 2017-05-30 Zoll Circulation, Inc. Heat exchange catheters with bi-directional fluid flow and their methods of manufacture and use
US8894563B2 (en) 2012-08-10 2014-11-25 Attenuex Technologies, Inc. Methods and systems for performing a medical procedure
US9717625B2 (en) * 2012-09-28 2017-08-01 Zoll Circulation, Inc. Intravascular heat exchange catheter with non-round coiled coolant path
US9433528B2 (en) 2012-09-28 2016-09-06 Zoll Circulation, Inc. Intravascular heat exchange catheter with rib cage-like coolant path
US9801756B2 (en) 2012-09-28 2017-10-31 Zoll Circulation, Inc. Intravascular heat exchange catheter and system with RFID coupling
US9278023B2 (en) 2012-12-14 2016-03-08 Zoll Circulation, Inc. System and method for management of body temperature
USD748252S1 (en) 2013-02-08 2016-01-26 C. R. Bard, Inc. Multi-lumen catheter tip
EP3964150A1 (en) * 2013-03-04 2022-03-09 CSA Medical, Inc. Cryospray catheters
US9474644B2 (en) 2014-02-07 2016-10-25 Zoll Circulation, Inc. Heat exchange system for patient temperature control with multiple coolant chambers for multiple heat exchange modalities
US11033424B2 (en) 2014-02-14 2021-06-15 Zoll Circulation, Inc. Fluid cassette with tensioned polymeric membranes for patient heat exchange system
US10792185B2 (en) 2014-02-14 2020-10-06 Zoll Circulation, Inc. Fluid cassette with polymeric membranes and integral inlet and outlet tubes for patient heat exchange system
CN105336339B (en) 2014-06-03 2019-05-03 华为技术有限公司 A kind for the treatment of method and apparatus of voice frequency signal
EP3861949A1 (en) 2014-06-04 2021-08-11 CSA Medical, Inc. Method and system for consistent, repeatable, and safe cryospray treatment of airway tissue
US9709609B2 (en) 2014-07-14 2017-07-18 Covidien Lp Systems and methods for improving the range of sensor systems
WO2016011091A1 (en) 2014-07-14 2016-01-21 C. R. Bard, Inc. Apparatuses, systems, and methods for inserting split tip catheters having enhanced stiffening and guiding features
US9784263B2 (en) 2014-11-06 2017-10-10 Zoll Circulation, Inc. Heat exchange system for patient temperature control with easy loading high performance peristaltic pump
US11359620B2 (en) 2015-04-01 2022-06-14 Zoll Circulation, Inc. Heat exchange system for patient temperature control with easy loading high performance peristaltic pump
BR102015002008A2 (en) * 2015-01-28 2016-08-23 Bernardo Lembo Conde De Paiva catheter
US11213423B2 (en) 2015-03-31 2022-01-04 Zoll Circulation, Inc. Proximal mounting of temperature sensor in intravascular temperature management catheter
US10537465B2 (en) 2015-03-31 2020-01-21 Zoll Circulation, Inc. Cold plate design in heat exchanger for intravascular temperature management catheter and/or heat exchange pad
US10022265B2 (en) 2015-04-01 2018-07-17 Zoll Circulation, Inc. Working fluid cassette with hinged plenum or enclosure for interfacing heat exchanger with intravascular temperature management catheter
JPWO2018123958A1 (en) * 2016-12-27 2019-10-31 日本ゼオン株式会社 Balloon catheter for IABP
US10758406B2 (en) 2016-12-30 2020-09-01 Zoll Circulation, Inc. High efficiency heat exchange catheters for control of patient body temperature
US10561528B2 (en) 2016-12-30 2020-02-18 Zoll Circulation, Inc. Fluid-circulating catheters useable for endovascular heat exchange
US11185440B2 (en) 2017-02-02 2021-11-30 Zoll Circulation, Inc. Devices, systems and methods for endovascular temperature control
KR102560026B1 (en) 2017-04-07 2023-07-26 팔메라 메디컬, 아이엔씨. treatment organ cooling
EP3437579B1 (en) * 2017-08-04 2023-07-12 Erbe Elektromedizin GmbH Cryosurgical instrument
EP3586893A1 (en) 2018-06-21 2020-01-01 Medtronic, Inc. Optimized intrathecal drug delivery
EP3593833A1 (en) 2018-07-13 2020-01-15 Medtronic Inc. Catheter for increased intrathecal drug dispersion
CN113677256A (en) 2019-02-07 2021-11-19 索雷斯医疗公司 Pressure attenuation device
US11344714B2 (en) 2019-11-04 2022-05-31 Medtronic, Inc. Intrathecal catheter with features to reduce drug dispersion
EP4268744A1 (en) * 2022-04-27 2023-11-01 Cryovasc GmbH Medical cryotherapy device with heat transfer body

Family Cites Families (293)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2374609A (en) 1945-04-24 Heating apparatus
US3125096A (en) 1964-03-17 Compressor
US2308484A (en) 1939-01-16 1943-01-19 Davol Rubber Co Catheter
US2615686A (en) 1948-05-29 1952-10-28 Servel Inc Heat transfer device
US2672032A (en) 1951-10-19 1954-03-16 Towse Robert Albert Edward Carcass freezing device
US2913009A (en) 1956-07-16 1959-11-17 Calumet & Hecla Internal and internal-external surface heat exchange tubing
US3425419A (en) 1964-08-08 1969-02-04 Angelo Actis Dato Method of lowering and raising the temperature of the human body
US3298371A (en) 1965-02-11 1967-01-17 Arnold S J Lee Freezing probe for the treatment of tissue, especially in neurosurgery
US3504674A (en) 1966-12-22 1970-04-07 Emil S Swenson Method and apparatus for performing hypothermia
US3460538A (en) 1967-10-20 1969-08-12 Edward T Armstrong Hypothermia apparatus and method for treating the human body and the like
US3604419A (en) 1968-09-19 1971-09-14 Technion Res & Dev Foundation Apparatus for urinary bladder treatment
US3612175A (en) 1969-07-01 1971-10-12 Olin Corp Corrugated metal tubing
US4370983A (en) 1971-01-20 1983-02-01 Lichtenstein Eric Stefan Computer-control medical care system
US3865116A (en) 1973-04-09 1975-02-11 Harold W Brooks Method of controlling tissue hypothermia
US3888259A (en) 1973-08-21 1975-06-10 Robert C Miley Hypothermia system
NL7414546A (en) 1973-11-15 1975-05-20 Rhone Poulenc Sa SMOOTH HEATING TUBE AND PROCESS FOR MANUFACTURING IT.
DE2422103C2 (en) 1974-05-07 1986-12-18 Erbe Elektromedizin Gmbh, 7400 Tuebingen Cryosurgical device
GB1582135A (en) 1976-07-14 1980-12-31 Ferranti Ltd Heaters
JPS5722883Y2 (en) 1977-02-21 1982-05-18
US4190033A (en) 1977-02-23 1980-02-26 Foti Thomas M Closed flow caloric test method
JPS6121041Y2 (en) 1977-08-04 1986-06-24
US4275734A (en) 1977-08-12 1981-06-30 Valleylab, Inc. Cryosurgical apparatus and method
US4153048A (en) 1977-09-14 1979-05-08 Cleveland Clinic Foundation Thermodilution catheter and method
US4231425A (en) 1978-02-27 1980-11-04 Engstrom William R Extracorporeal circuit blood heat exchanger
US4323071A (en) 1978-04-24 1982-04-06 Advanced Catheter Systems, Inc. Vascular guiding catheter assembly and vascular dilating catheter assembly and a combination thereof and methods of making the same
SU806029A1 (en) 1978-05-03 1981-02-23 Иркутский Государственный Медицинс-Кий Институт Method of monitoring degree of perfused cooling of brain
JPS55100959A (en) 1979-01-26 1980-08-01 Nisshin Steel Co Ltd Invar alloy with excellent welding high temperature crack resistance and strain corrosion crack resistance
US4318722A (en) 1980-04-09 1982-03-09 Gerald Altman Infrared radiation cooler for producing physiologic conditions such as a comfort or hypothermia
US4445500A (en) 1982-03-03 1984-05-01 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4298006A (en) 1980-04-30 1981-11-03 Research Against Cancer, Inc. Systemic hyperthermia with improved temperature sensing apparatus and method
US4731072A (en) 1981-05-11 1988-03-15 Mcneilab, Inc. Apparatus for heating or cooling fluids
US4427009A (en) 1981-06-30 1984-01-24 Minnesota Mining And Manufacturing Company Integrated cardioplegia delivery system
US4484586A (en) 1982-05-27 1984-11-27 Berkley & Company, Inc. Hollow conductive medical tubing
US4569355A (en) 1982-05-28 1986-02-11 Hemodynamics Technology, Inc. Method and apparatus for monitoring and diagnosing peripheral blood flow
JPS5929985A (en) 1982-08-11 1984-02-17 Hitachi Ltd Constant pressure type boiling and cooling device
US4973493A (en) 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US4483341A (en) 1982-12-09 1984-11-20 Atlantic Richfield Company Therapeutic hypothermia instrument
US4581017B1 (en) 1983-03-07 1994-05-17 Bard Inc C R Catheter systems
US4747826A (en) 1983-06-08 1988-05-31 University Of Pittsburgh Rapid venous infusion system
US4490237A (en) 1983-07-01 1984-12-25 Dravo Corporation Process for recovering heat from the combustion of residual carbon in oil depleted shale
USRE33911E (en) 1983-07-13 1992-05-05 Advanced Cardiovascular Systems, Inc. Catheter guide wire with short spring tip and method of using the same
US4672962A (en) 1983-09-28 1987-06-16 Cordis Corporation Plaque softening method
US4796640A (en) 1984-01-13 1989-01-10 American Hospital Supply Corporation Apparatus with fast response thermistor
US4602642A (en) 1984-10-23 1986-07-29 Intelligent Medical Systems, Inc. Method and apparatus for measuring internal body temperature utilizing infrared emissions
US5019075A (en) 1984-10-24 1991-05-28 The Beth Israel Hospital Method and apparatus for angioplasty
DE3442736A1 (en) 1984-11-23 1986-06-05 Tassilo Dr.med. 7800 Freiburg Bonzel DILATATION CATHETER
US4739492A (en) 1985-02-21 1988-04-19 Cochran Michael J Dialysis machine which verifies operating parameters
SE457388B (en) 1985-06-04 1988-12-19 Gambro Ab MONITOR FOR CONTROL AND / OR CONTROL OF TWO OR MULTIPLE FUNCTIONS AND APPLICATION OF SUCH CIRCULAR CONTROL
US4748979A (en) 1985-10-07 1988-06-07 Cordis Corporation Plaque resolving device
US4655746A (en) 1985-12-02 1987-04-07 Target Therapeutics Catheter device
US4817624A (en) 1985-12-20 1989-04-04 The General Hospital Corporation Mini-bolus technique for thermodilution cardiac output measurements
US4920963A (en) 1986-02-28 1990-05-01 Brader Eric W Apparatus for preventing brain damage during cardiac arrest, CPR or severe shock
US4750493A (en) 1986-02-28 1988-06-14 Brader Eric W Method of preventing brain damage during cardiac arrest, CPR or severe shock
US5089260A (en) 1986-05-15 1992-02-18 Emory University Method of treating ischemic tissue
DE3621350A1 (en) 1986-06-26 1988-01-14 Bonzel Tassilo DILATATION CATHETER WITH AN EXPANDABLE BALLOON
US4745922A (en) 1986-07-11 1988-05-24 Taylor Kenneth G Cervical heat transfer and immobilization device
US4979959A (en) 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
US5018521A (en) 1986-10-24 1991-05-28 Campbell William P Method of and apparatus for increased transfer of heat into or out of the body
DE3636995A1 (en) 1986-10-30 1988-05-11 Fresenius Ag METHOD AND DEVICE FOR EXTRACTING HEAT FROM BLOOD IN THE EXTRACORPORAL CIRCUIT
US5046497A (en) 1986-11-14 1991-09-10 Millar Instruments, Inc. Structure for coupling a guidewire and a catheter
US4781799A (en) 1986-12-08 1988-11-01 Xerox Corporation Electroforming apparatus and process
US5358486A (en) 1987-01-09 1994-10-25 C. R. Bard, Inc. Multiple layer high strength balloon for dilatation catheter
US4762130A (en) 1987-01-15 1988-08-09 Thomas J. Fogarty Catheter with corkscrew-like balloon
US5024668A (en) 1987-01-20 1991-06-18 Rocky Mountain Research, Inc. Retrograde perfusion system, components and method
US4819655A (en) 1987-08-04 1989-04-11 Webler William E Injectateless thermal cardiac output determination method and apparatus
US4820349A (en) 1987-08-21 1989-04-11 C. R. Bard, Inc. Dilatation catheter with collapsible outer diameter
JPS6446056U (en) 1987-09-17 1989-03-22
US4964409A (en) 1989-05-11 1990-10-23 Advanced Cardiovascular Systems, Inc. Flexible hollow guiding member with means for fluid communication therethrough
US4860744A (en) 1987-11-02 1989-08-29 Raj K. Anand Thermoelectrically controlled heat medical catheter
US5041089A (en) 1987-12-11 1991-08-20 Devices For Vascular Intervention, Inc. Vascular dilation catheter construction
FR2626476B1 (en) 1988-02-01 1997-10-17 Boussignac Georges PROBE FOR INTRODUCTION INSIDE A LIVING BODY
US4951677A (en) 1988-03-21 1990-08-28 Prutech Research And Development Partnership Ii Acoustic imaging catheter and the like
US5423745A (en) 1988-04-28 1995-06-13 Research Medical, Inc. Irregular surface balloon catheters for body passageways and methods of use
US4904237A (en) 1988-05-16 1990-02-27 Janese Woodrow W Apparatus for the exchange of cerebrospinal fluid and a method of treating brain and spinal cord injuries
US4949718B1 (en) * 1988-09-09 1998-11-10 Gynelab Products Intrauterine cauterizing apparatus
US4883455A (en) 1988-09-13 1989-11-28 Minnesota Mining And Manufacturing Company Cardioplegia administration set
US5147355A (en) 1988-09-23 1992-09-15 Brigham And Womens Hospital Cryoablation catheter and method of performing cryoablation
US5014695A (en) 1988-10-04 1991-05-14 Benak Arnold M Kidney cooling jacket
US5151100A (en) 1988-10-28 1992-09-29 Boston Scientific Corporation Heating catheters
US5191883A (en) 1988-10-28 1993-03-09 Prutech Research And Development Partnership Ii Device for heating tissue in a patient's body
US4955377A (en) 1988-10-28 1990-09-11 Lennox Charles D Device and method for heating tissue in a patient's body
US5108390A (en) 1988-11-14 1992-04-28 Frigitronics, Inc. Flexible cryoprobe
GB2226497B (en) 1988-12-01 1992-07-01 Spembly Medical Ltd Cryosurgical probe
US5110721A (en) 1989-02-10 1992-05-05 The Research Foundation Of State University Of New York Method for hypothermic organ protection during organ retrieval
JP2749646B2 (en) 1989-07-12 1998-05-13 関西ペイント株式会社 Positive photosensitive electrodeposition coating composition and method for producing circuit board using the same
WO1991005528A1 (en) * 1989-10-19 1991-05-02 Granulab B.V. Device for cooling or heating a person
EP0424179A3 (en) 1989-10-20 1991-12-27 John William Olney Use of combined excitatory amino acid and cholinergic antagonists to prevent neurological deterioration
US5174285A (en) 1990-01-08 1992-12-29 Lake Shore Medical Development Partners Ltd. Localized heat transfer device
US5549559A (en) 1990-03-22 1996-08-27 Argomed Ltd. Thermal treatment apparatus
IL93842A (en) 1990-03-22 1995-10-31 Argomed Ltd Apparatus for localized thermal treatment of mammals
US5106368A (en) 1990-04-20 1992-04-21 Cook Incorporated Collapsible lumen catheter for extracorporeal treatment
US5265670A (en) 1990-04-27 1993-11-30 International Business Machines Corporation Convection transfer system
US5342301A (en) 1992-08-13 1994-08-30 Advanced Polymers Incorporated Multi-lumen balloons and catheters made therewith
US5624392A (en) 1990-05-11 1997-04-29 Saab; Mark A. Heat transfer catheters and methods of making and using same
US5092841A (en) 1990-05-17 1992-03-03 Wayne State University Method for treating an arterial wall injured during angioplasty
US5196024A (en) 1990-07-03 1993-03-23 Cedars-Sinai Medical Center Balloon catheter with cutting edge
US5417686A (en) 1990-07-10 1995-05-23 The Texas A&M University System Temperature control mechanisms for a micro heat pipe catheter
US5190539A (en) 1990-07-10 1993-03-02 Texas A & M University System Micro-heat-pipe catheter
US5188602A (en) * 1990-07-12 1993-02-23 Interventional Thermodynamics, Inc. Method and device for delivering heat to hollow body organs
DE69130924T2 (en) * 1990-08-29 1999-08-05 Us Health CAPSAICIN OR ITS DERIVATIVES OR ANALOG-CONTAINING BIRD FEED
US5330519B1 (en) 1990-09-05 1998-11-10 Breg Inc Therapeutic nonambient temperature fluid circulation system
EP0548122A1 (en) 1990-09-14 1993-06-30 American Medical Systems, Inc. Combined hyperthermia and dilation catheter
US5059057A (en) 1990-10-05 1991-10-22 Andrew Graef High strength, thin-walled, plastic tubes and connector combination and method of fabrication
US5584804A (en) 1990-10-10 1996-12-17 Life Resuscitation Technologies, Inc. Brain resuscitation and organ preservation device and method for performing the same
US5395314A (en) 1990-10-10 1995-03-07 Life Resuscitation Technologies, Inc. Brain resuscitation and organ preservation device and method for performing the same
US5827222A (en) 1990-10-10 1998-10-27 Life Resuscitation Technologies, Inc. Method of treating at least one of brain and associated nervous tissue injury
US5149321A (en) 1990-10-10 1992-09-22 Klatz Ronald M Brain resuscitation device and method for performing the same
US5112438A (en) 1990-11-29 1992-05-12 Hughes Aircraft Company Photolithographic method for making helices for traveling wave tubes and other cylindrical objects
US5139496A (en) * 1990-12-20 1992-08-18 Hed Aharon Z Ultrasonic freeze ablation catheters and probes
US5308320A (en) 1990-12-28 1994-05-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Portable and modular cardiopulmonary bypass apparatus and associated aortic balloon catheter and associated method
US5553622A (en) 1991-01-29 1996-09-10 Mckown; Russell C. System and method for controlling the temperature of a catheter-mounted heater
US5156151A (en) 1991-02-15 1992-10-20 Cardiac Pathways Corporation Endocardial mapping and ablation system and catheter probe
US5117822A (en) 1991-04-05 1992-06-02 Laghi Aldo A Silicone heart spoon
JP3091253B2 (en) 1991-04-25 2000-09-25 オリンパス光学工業株式会社 Thermal treatment equipment
DE9105229U1 (en) 1991-04-27 1991-06-13 B. Braun Melsungen Ag, 3508 Melsungen, De
US5261399A (en) 1991-05-22 1993-11-16 Klatz Ronald M Brain cooling device and method for performing the same
US6277143B1 (en) 1991-05-22 2001-08-21 Life Science Holdings, Inc. Brain cooling apparatus and method for cooling the brain
US5250070A (en) 1991-05-28 1993-10-05 Parodi Juan C Less traumatic angioplasty balloon for arterial dilatation
US5236908A (en) 1991-06-07 1993-08-17 Gensia Pharmaceuticals, Inc. Methods of treating injury to the central nervous system
US5264260A (en) 1991-06-20 1993-11-23 Saab Mark A Dilatation balloon fabricated from low molecular weight polymers
US5326165A (en) 1991-06-26 1994-07-05 Irvine Scientific Sales Co. Mixing apparatus
US5180364A (en) 1991-07-03 1993-01-19 Robert Ginsburg Valved self-perfusing catheter guide
US5766151A (en) * 1991-07-16 1998-06-16 Heartport, Inc. Endovascular system for arresting the heart
US5558644A (en) 1991-07-16 1996-09-24 Heartport, Inc. Retrograde delivery catheter and method for inducing cardioplegic arrest
US5795325A (en) 1991-07-16 1998-08-18 Heartport, Inc. Methods and apparatus for anchoring an occluding member
US5211631A (en) 1991-07-24 1993-05-18 Sheaff Charles M Patient warming apparatus
CA2074304C (en) 1991-08-02 1996-11-26 Cyril J. Schweich, Jr. Drug delivery catheter
US5150706A (en) 1991-08-15 1992-09-29 Cox James L Cooling net for cardiac or transplant surgery
US5520682A (en) 1991-09-06 1996-05-28 Cryomedical Sciences, Inc. Cryosurgical instrument with vent means and method using same
US5267341A (en) 1991-10-30 1993-11-30 Baxter International Inc. Fluid catheter with aqueous fluid core and method of use
US5269369A (en) 1991-11-18 1993-12-14 Wright State University Temperature regulation system for the human body using heat pipes
US5246421A (en) 1992-02-12 1993-09-21 Saab Mark A Method of treating obstructed regions of bodily passages
US5413588A (en) 1992-03-06 1995-05-09 Urologix, Inc. Device and method for asymmetrical thermal therapy with helical dipole microwave antenna
US5239999A (en) 1992-03-27 1993-08-31 Cardiac Pathways Corporation Helical endocardial catheter probe
US5281213A (en) 1992-04-16 1994-01-25 Implemed, Inc. Catheter for ice mapping and ablation
US5423807A (en) 1992-04-16 1995-06-13 Implemed, Inc. Cryogenic mapping and ablation catheter
US5281215A (en) 1992-04-16 1994-01-25 Implemed, Inc. Cryogenic catheter
US5578008A (en) 1992-04-22 1996-11-26 Japan Crescent, Inc. Heated balloon catheter
US5395331A (en) 1992-04-27 1995-03-07 Minnesota Mining And Manufacturing Company Retrograde coronary sinus catheter having a ribbed balloon
US5269758A (en) 1992-04-29 1993-12-14 Taheri Syde A Intravascular catheter and method for treatment of hypothermia
US5269749A (en) 1992-05-08 1993-12-14 Cobe Laboratories, Inc. Heat exchange device for inducing cardioplegia
US5248312A (en) 1992-06-01 1993-09-28 Sensor Electronics, Inc. Liquid metal-filled balloon
US6623516B2 (en) 1992-08-13 2003-09-23 Mark A. Saab Method for changing the temperature of a selected body region
US5322514A (en) 1992-08-19 1994-06-21 Sherwood Medical Company Needle assembly with detachable wing
US5383918A (en) 1992-08-31 1995-01-24 Panetta; Thomas F. Hypothermia reducing body exclosure
US5342621A (en) 1992-09-15 1994-08-30 Advanced Cardiovascular Systems, Inc. Antithrombogenic surface
US5403281A (en) 1992-09-25 1995-04-04 Minnesota Mining And Manufacturing Company Inline heat exchanger and cardioplegia system
US5334193A (en) 1992-11-13 1994-08-02 American Cardiac Ablation Co., Inc. Fluid cooled ablation catheter
US5676693A (en) 1992-11-13 1997-10-14 Scimed Life Systems, Inc. Electrophysiology device
US5365750A (en) 1992-12-18 1994-11-22 California Aquarium Supply Remote refrigerative probe
US5306261A (en) 1993-01-22 1994-04-26 Misonix, Inc. Catheter with collapsible wire guide
US5437673A (en) 1993-02-04 1995-08-01 Cryomedical Sciences, Inc. Closed circulation tissue warming apparatus and method of using the same in prostate surgery
US5837003A (en) 1993-02-10 1998-11-17 Radiant Medical, Inc. Method and apparatus for controlling a patient's body temperature by in situ blood temperature modification
US6033383A (en) 1996-12-19 2000-03-07 Ginsburg; Robert Temperature regulating catheter and methods
US5486208A (en) 1993-02-10 1996-01-23 Ginsburg; Robert Method and apparatus for controlling a patient's body temperature by in situ blood temperature modification
US6110168A (en) 1993-02-10 2000-08-29 Radiant Medical, Inc. Method and apparatus for controlling a patient's body temperature by in situ blood temperature modifications
US6620188B1 (en) 1998-08-24 2003-09-16 Radiant Medical, Inc. Methods and apparatus for regional and whole body temperature modification
US5799661A (en) 1993-02-22 1998-09-01 Heartport, Inc. Devices and methods for port-access multivessel coronary artery bypass surgery
US5354272A (en) 1993-03-02 1994-10-11 Baxter International Inc. Improved injectate delivery system
US5322515A (en) 1993-03-15 1994-06-21 Abbott Laboratories Luer adapter assembly for emergency syringe
US6007692A (en) 1993-04-05 1999-12-28 Xerox Corporation Electroforming mandrels with contoured surfaces
US5330435A (en) 1993-04-08 1994-07-19 Vaillancourt Vincent L Valve for a catheter assembly
US5713941A (en) 1993-04-27 1998-02-03 Cancer Research Institute Apparatus for inducing whole body hyperthermia and method for treatment utilizing said whole body hyperthermia inducing apparatus
US5873835A (en) 1993-04-29 1999-02-23 Scimed Life Systems, Inc. Intravascular pressure and flow sensor
US5536247A (en) 1993-06-10 1996-07-16 Scimed Life Systems, Inc. Method of treating cardiac conduction defects
US5630837A (en) 1993-07-01 1997-05-20 Boston Scientific Corporation Acoustic ablation
US5545708A (en) 1993-07-14 1996-08-13 Becton, Dickinson And Company Thermoplastic polyurethane method of making same and forming a medical article therefrom
US5364364A (en) 1993-08-04 1994-11-15 Ivac Corporation Automatic flow control valve system
US5626618A (en) 1993-09-24 1997-05-06 The Ohio State University Mechanical adjunct to cardiopulmonary resuscitation (CPR), and an electrical adjunct to defibrillation countershock, cardiac pacing, and cardiac monitoring
US5871526A (en) 1993-10-13 1999-02-16 Gibbs; Roselle Portable temperature control system
NL9301851A (en) 1993-10-26 1995-05-16 Cordis Europ Cryo-ablation catheter.
US5462521A (en) 1993-12-21 1995-10-31 Angeion Corporation Fluid cooled and perfused tip for a catheter
US6099524A (en) 1994-01-28 2000-08-08 Cardiac Pacemakers, Inc. Electrophysiological mapping and ablation catheter and method
US5617854A (en) 1994-06-22 1997-04-08 Munsif; Anand Shaped catheter device and method
US5622182A (en) 1994-06-27 1997-04-22 Jaffe; Richard A. System for measuring core body temperature in vivo
US5716386A (en) 1994-06-27 1998-02-10 The Ohio State University Non-invasive aortic impingement and core and cerebral temperature manipulation
US5967976A (en) 1994-08-19 1999-10-19 Novoste Corporation Apparatus and methods for procedures related to the electrophysiology of the heart
US5499973A (en) 1994-09-08 1996-03-19 Saab; Mark A. Variable stiffness balloon dilatation catheters
US6190354B1 (en) 1994-09-16 2001-02-20 Scimed Life Systems, Inc. Balloon catheter with improved pressure source
US5545133A (en) 1994-09-16 1996-08-13 Scimed Life Systems, Inc. Balloon catheter with improved pressure source
US5486204A (en) 1994-09-20 1996-01-23 University Of Texas Health Science Center Houston Method of treating a non-penetrating head wound with hypothermia
US5545194A (en) 1994-09-30 1996-08-13 Augustine Medical, Inc. Convertible thermal blanket
US5833673A (en) 1994-11-02 1998-11-10 Daig Corporation Guiding introducer system for use in the treatment of left ventricular tachycardia
US5573532A (en) 1995-01-13 1996-11-12 Cryomedical Sciences, Inc. Cryogenic surgical instrument and method of manufacturing the same
US5957917A (en) 1995-01-20 1999-09-28 Miravant Systems, Inc. Transluminal hyperthermia catheter and method for use
US5647051A (en) 1995-02-22 1997-07-08 Seabrook Medical Systems, Inc. Cold therapy system with intermittent fluid pumping for temperature control
US5624342A (en) 1995-06-26 1997-04-29 Younger; Gilbert W. Method for modifying an original automatic transmission
US6314754B1 (en) 2000-04-17 2001-11-13 Igor K. Kotliar Hypoxic fire prevention and fire suppression systems for computer rooms and other human occupied facilities
US5653692A (en) 1995-09-07 1997-08-05 Innerdyne Medical, Inc. Method and system for direct heating of fluid solution in a hollow body organ
US5891094A (en) 1995-09-07 1999-04-06 Innerdyne, Inc. System for direct heating of fluid solution in a hollow body organ and methods
US5642197A (en) 1995-09-27 1997-06-24 Xerox Corporation System and method for enhancing color seperation utilizing multiple pass scanner in a single pass color scanner
US5824030A (en) 1995-12-21 1998-10-20 Pacesetter, Inc. Lead with inter-electrode spacing adjustment
US5800483A (en) 1996-03-21 1998-09-01 Microtek Medical, Inc. System and method for sterile surgical-thermal drape with active air circulation
US5871468A (en) 1996-04-24 1999-02-16 Medtronic, Inc. Medical catheter with a high pressure/low compliant balloon
US5733319A (en) 1996-04-25 1998-03-31 Urologix, Inc. Liquid coolant supply system
US6022336A (en) 1996-05-20 2000-02-08 Percusurge, Inc. Catheter system for emboli containment
US5861021A (en) * 1996-06-17 1999-01-19 Urologix Inc Microwave thermal therapy of cardiac tissue
US5827237A (en) 1996-06-17 1998-10-27 Cardeon Corporation Dual lumen catheter with controlled antegrade and retrograde fluid flow
US5833671A (en) 1996-06-17 1998-11-10 Cardeon Corporation Triple lumen catheter with controllable antegrade and retrograde fluid flow
US5800486A (en) 1996-06-17 1998-09-01 Urologix, Inc. Device for transurethral thermal therapy with cooling balloon
US5913886A (en) 1996-07-09 1999-06-22 Soloman; Alan Body temperature control system and method of temperature control
US5800487A (en) 1996-07-23 1998-09-01 Endocare, Inc. Cryoprobe
US5800516A (en) 1996-08-08 1998-09-01 Cordis Corporation Deployable and retrievable shape memory stent/tube and method
US5797878A (en) 1996-08-15 1998-08-25 Guidant Corporation Catheter having optimized balloon taper angle
US5964751A (en) 1996-08-26 1999-10-12 Illumenex Corporation Light delivery system with blood flushing capability
US5800480A (en) 1996-08-30 1998-09-01 Augustine Medical, Inc. Support apparatus with a plurality of thermal zones providing localized cooling
US5906636A (en) 1996-09-20 1999-05-25 Texas Heart Institute Heat treatment of inflamed tissue
US5891027A (en) * 1996-10-21 1999-04-06 Irvine Biomedical, Inc. Cardiovascular catheter system with an inflatable soft tip
US5916242A (en) 1996-11-04 1999-06-29 Schwartz; George R. Apparatus for rapid cooling of the brain and method of performing same
US5735809A (en) 1996-12-05 1998-04-07 Matria Healthcare, Inc. Fiber assembly for in vivo plasma separation
US5910104A (en) 1996-12-26 1999-06-08 Cryogen, Inc. Cryosurgical probe with disposable sheath
US6146814A (en) 1996-12-27 2000-11-14 Millet; Marcus J. Methods of making composite catheters
US5827269A (en) 1996-12-31 1998-10-27 Gynecare, Inc. Heated balloon having a reciprocating fluid agitator
US5906594A (en) 1997-01-08 1999-05-25 Symbiosis Corporation Endoscopic infusion needle having dual distal stops
US5879329A (en) 1997-01-22 1999-03-09 Radiant Medical, Inc. Infusion systems and methods for introducing fluids into the body within a desired temperature range
US5968009A (en) 1997-01-29 1999-10-19 Baxter International Inc. Double lumen tubing design for catheter
US5913854A (en) * 1997-02-04 1999-06-22 Medtronic, Inc. Fluid cooled ablation catheter and method for making
US5899898A (en) 1997-02-27 1999-05-04 Cryocath Technologies Inc. Cryosurgical linear ablation
US5868735A (en) 1997-03-06 1999-02-09 Scimed Life Systems, Inc. Cryoplasty device and method
US6024740A (en) 1997-07-08 2000-02-15 The Regents Of The University Of California Circumferential ablation device assembly
US5913856A (en) 1997-05-19 1999-06-22 Irvine Biomedical, Inc. Catheter system having a porous shaft and fluid irrigation capabilities
US6736837B2 (en) 1997-08-12 2004-05-18 James A. Fox Method for inducing hypothermia for treating neurological disorders
US5893838A (en) 1997-08-15 1999-04-13 Therox, Inc. System and method for high pressure delivery of gas-supersaturated fluids
US5971979A (en) 1997-12-02 1999-10-26 Odyssey Technologies, Inc. Method for cryogenic inhibition of hyperplasia
US6011995A (en) 1997-12-29 2000-01-04 The Regents Of The University Of California Endovascular device for hyperthermia and angioplasty and method for using the same
US6843800B1 (en) 1998-01-23 2005-01-18 Innercool Therapies, Inc. Patient temperature regulation method and apparatus
US6251130B1 (en) 1998-03-24 2001-06-26 Innercool Therapies, Inc. Device for applications of selective organ cooling
US6383210B1 (en) 2000-06-02 2002-05-07 Innercool Therapies, Inc. Method for determining the effective thermal mass of a body or organ using cooling catheter
US6464716B1 (en) 1998-01-23 2002-10-15 Innercool Therapies, Inc. Selective organ cooling apparatus and method
US6491039B1 (en) 1998-01-23 2002-12-10 Innercool Therapies, Inc. Medical procedure
US6251129B1 (en) 1998-03-24 2001-06-26 Innercool Therapies, Inc. Method for low temperature thrombolysis and low temperature thrombolytic agent with selective organ temperature control
US6991645B2 (en) 1998-01-23 2006-01-31 Innercool Therapies, Inc. Patient temperature regulation method and apparatus
US6245095B1 (en) 1998-03-24 2001-06-12 Innercool Therapies, Inc. Method and apparatus for location and temperature specific drug action such as thrombolysis
US6096068A (en) 1998-01-23 2000-08-01 Innercool Therapies, Inc. Selective organ cooling catheter and method of using the same
US6379378B1 (en) 2000-03-03 2002-04-30 Innercool Therapies, Inc. Lumen design for catheter
US6325818B1 (en) 1999-10-07 2001-12-04 Innercool Therapies, Inc. Inflatable cooling apparatus for selective organ hypothermia
US6558412B2 (en) 1998-01-23 2003-05-06 Innercool Therapies, Inc. Selective organ hypothermia method and apparatus
US6231595B1 (en) 1998-03-31 2001-05-15 Innercool Therapies, Inc. Circulating fluid hypothermia method and apparatus
US6051019A (en) * 1998-01-23 2000-04-18 Del Mar Medical Technologies, Inc. Selective organ hypothermia method and apparatus
US20010029394A1 (en) 1998-03-24 2001-10-11 Dobak John D. Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device
US6312452B1 (en) 1998-01-23 2001-11-06 Innercool Therapies, Inc. Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device
US6261312B1 (en) 1998-06-23 2001-07-17 Innercool Therapies, Inc. Inflatable catheter for selective organ heating and cooling and method of using the same
US6238428B1 (en) 1998-01-23 2001-05-29 Innercool Therapies, Inc. Selective organ cooling apparatus and method employing turbulence-inducing element with curved terminations
US6254626B1 (en) 1998-03-24 2001-07-03 Innercool Therapies, Inc. Articulation device for selective organ cooling apparatus
US6364899B1 (en) 1998-01-23 2002-04-02 Innercool Therapies, Inc. Heat pipe nerve cooler
US6491716B2 (en) 1998-03-24 2002-12-10 Innercool Therapies, Inc. Method and device for applications of selective organ cooling
US6295990B1 (en) 1998-02-03 2001-10-02 Salient Interventional Systems, Inc. Methods and systems for treating ischemia
JPH11225991A (en) 1998-02-19 1999-08-24 Toshiba Corp Body temperature monitoring device and method
US6042559A (en) 1998-02-24 2000-03-28 Innercool Therapies, Inc. Insulated catheter for selective organ perfusion
US6224624B1 (en) 1998-03-24 2001-05-01 Innercool Therapies, Inc. Selective organ cooling apparatus and method
US20020091429A1 (en) 1998-03-24 2002-07-11 Innercool Therapies, Inc. Method and device for applications of selective organ cooling
US6599312B2 (en) 1998-03-24 2003-07-29 Innercool Therapies, Inc. Isolated selective organ cooling apparatus
US6576002B2 (en) 1998-03-24 2003-06-10 Innercool Therapies, Inc. Isolated selective organ cooling method and apparatus
DE69934303T2 (en) 1998-03-24 2007-07-05 Innercool Therapies, Inc., San Diego DEVICE FOR COOLING A SELECTED ORGAN
US6551349B2 (en) 1998-03-24 2003-04-22 Innercool Therapies, Inc. Selective organ cooling apparatus
US7291144B2 (en) 1998-03-31 2007-11-06 Innercool Therapies, Inc. Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation
US6685732B2 (en) 1998-03-31 2004-02-03 Innercool Therapies, Inc. Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing microporous balloon
US6368304B1 (en) 1999-02-19 2002-04-09 Alsius Corporation Central venous catheter with heat exchange membrane
US6419643B1 (en) 1998-04-21 2002-07-16 Alsius Corporation Central venous catheter with heat exchange properties
US6126684A (en) 1998-04-21 2000-10-03 The Regents Of The University Of California Indwelling heat exchange catheter and method of using same
US6149670A (en) 1999-03-11 2000-11-21 Alsius Corporation Method and system for treating cardiac arrest using hypothermia
US6338727B1 (en) 1998-08-13 2002-01-15 Alsius Corporation Indwelling heat exchange catheter and method of using same
US6520933B1 (en) 1998-04-21 2003-02-18 Alsius Corporation Central venous line cooling catheter having a spiral-shaped heat exchange member
US6682551B1 (en) 1999-03-11 2004-01-27 Alsius Corporation Method and system for treating cardiac arrest using hypothermia
US20020007203A1 (en) 1998-06-23 2002-01-17 Innercool Therapies, Inc. Method of manufacturing a heat transfer element for in vivo cooling
US6319248B1 (en) 1998-07-29 2001-11-20 Cryocath Technologies, Inc. Spray catheter
US6450990B1 (en) 1998-08-13 2002-09-17 Alsius Corporation Catheter with multiple heating/cooling fibers employing fiber spreading features
US6610083B2 (en) 1998-08-24 2003-08-26 Radiant Medical, Inc. Multiple lumen heat exchange catheters
US6620189B1 (en) 2000-02-28 2003-09-16 Radiant Medical, Inc. Method and system for control of a patient's body temperature by way of a transluminally insertable heat exchange catheter
US6063101A (en) 1998-11-20 2000-05-16 Precision Vascular Systems, Inc. Stent apparatus and method
US6290697B1 (en) 1998-12-01 2001-09-18 Irvine Biomedical, Inc. Self-guiding catheter system for tissue ablation
US6146411A (en) 1998-12-24 2000-11-14 Alsius Corporation Cooling system for indwelling heat exchange catheter
US6451011B2 (en) 1999-01-19 2002-09-17 Hosheng Tu Medical device having temperature sensing and ablation capabilities
US6405080B1 (en) 1999-03-11 2002-06-11 Alsius Corporation Method and system for treating cardiac arrest
US6299599B1 (en) 1999-02-19 2001-10-09 Alsius Corporation Dual balloon central venous line catheter temperature control system
EP1205167B1 (en) 1999-02-19 2006-10-11 Alsius Corporation Central venous line catheter having temperature control system
US6019783A (en) 1999-03-02 2000-02-01 Alsius Corporation Cooling system for therapeutic catheter
US6290717B1 (en) 1999-03-31 2001-09-18 Alsius Corporation Temperature probe and interconnect cable for hypothermia catheter temperature feedback
US6165207A (en) 1999-05-27 2000-12-26 Alsius Corporation Method of selectively shaping hollow fibers of heat exchange catheter
US6336911B1 (en) 1999-06-16 2002-01-08 First Circle Medical, Inc. Thermal sensor for hyperthermia system
US6287326B1 (en) 1999-08-02 2001-09-11 Alsius Corporation Catheter with coiled multi-lumen heat transfer extension
US6231594B1 (en) 1999-08-11 2001-05-15 Radiant Medical, Inc. Method of controlling body temperature while reducing shivering
US6264679B1 (en) 1999-08-20 2001-07-24 Radiant Medical, Inc. Heat exchange catheter with discrete heat exchange elements
AU4713601A (en) 1999-12-07 2001-06-18 Alsius Corporation Method and system for treating stroke using hypothermia
US6648906B2 (en) 2000-04-06 2003-11-18 Innercool Therapies, Inc. Method and apparatus for regulating patient temperature by irrigating the bladder with a fluid
US6354099B1 (en) 2000-04-11 2002-03-12 Augustine Medical, Inc. Cooling devices with high-efficiency cooling features
US6726708B2 (en) 2000-06-14 2004-04-27 Innercool Therapies, Inc. Therapeutic heating and cooling via temperature management of a colon-inserted balloon
JP2002026750A (en) 2000-07-07 2002-01-25 Pioneer Electronic Corp Receiver
US6699268B2 (en) 2000-12-15 2004-03-02 Alsius Corporation Radio frequency patient heating system
US6602243B2 (en) 2000-12-15 2003-08-05 Alsius Corporation Foley catheter having redundant temperature sensors and method
US6544282B1 (en) * 2001-02-21 2003-04-08 Radiant Medical, Inc. Inhibition of platelet activation, aggregation and/or adhesion by hypothermia
US6451045B1 (en) 2001-02-22 2002-09-17 Alsius Corporation Heat exchange catheter having a helically wrapped heat exchanger
US6641603B2 (en) 2001-04-13 2003-11-04 Alsius Corporation Heat exchange catheter having helically wound reinforcement

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CA2335997A1 (en) 1999-12-29
US6676689B2 (en) 2004-01-13
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US6540771B2 (en) 2003-04-01
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US6695873B2 (en) 2004-02-24
US6648908B2 (en) 2003-11-18
AU756941B2 (en) 2003-01-30
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US20010008975A1 (en) 2001-07-19
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US20020103519A1 (en) 2002-08-01
US20020095200A1 (en) 2002-07-18
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US7651518B2 (en) 2010-01-26
WO1999066970A1 (en) 1999-12-29
US6533804B2 (en) 2003-03-18
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CA2419457C (en) 2010-03-09
US6261312B1 (en) 2001-07-17
CA2335997C (en) 2003-05-20
WO1999066970A9 (en) 2000-07-20
AU2005229706A1 (en) 2005-11-24
US20010001832A1 (en) 2001-05-24
US20020091430A1 (en) 2002-07-11
AU2003204199B2 (en) 2005-08-04
US20040106969A1 (en) 2004-06-03
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JP4474103B2 (en) 2010-06-02
JP2007190430A (en) 2007-08-02

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