CA2438760A1 - Transfert needle assembly - Google Patents
Transfert needle assembly Download PDFInfo
- Publication number
- CA2438760A1 CA2438760A1 CA 2438760 CA2438760A CA2438760A1 CA 2438760 A1 CA2438760 A1 CA 2438760A1 CA 2438760 CA2438760 CA 2438760 CA 2438760 A CA2438760 A CA 2438760A CA 2438760 A1 CA2438760 A1 CA 2438760A1
- Authority
- CA
- Canada
- Prior art keywords
- puncture
- needle
- tip
- puncture needle
- proximal end
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2075—Venting means for external venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2079—Filtering means
- A61J1/2082—Filtering means for gas filtration
Abstract
A transfer needle assembly includes a tubular guide member 1 haying a top surface 11, a skirt portion 13, and a puncture needle insertion portion 12; and a puncture member 2 of which tip 223 is fitted in the puncture needle insertion portion 12 such that thp tip 223 can slide from a position where it is receded into the skirt portion 13 to a position. where it projects from the skirt portion 13. The puncture member 2 is a tubular member having a tip fitting portion 21 at the proximal end thereof and, at the distal end thereof, a puncture needle 22 to be inserted into the puncture needle insertion portion 12. The puncture needle 22 is provided with a liquid passage 222 that communicates with the tip fitting portion 21 and a gas passage 221 that is open to the outside through an air filter 231.
Description
TP,ANSFER NEEDLE ASSEMBLY
Field of the Invention The present invent ion relates to a transfer needle assembly for transferring fluid from a fluid source to a vial contairLing a solid :nat~rial or a liquid material. The transfer needle assembly of the present invention eliminates problems such as contamination of a tip of a puncture needle in the transfer needle assembly before use and inj ury to an operator' s f l nger by the tip of the puncture needle and flu? d leakage from the transfer needle assembly when in use.
Background of th=_ Tnvention In order to prepare a Iiquidmedical component for adhering tissues in a living body or to be mixed with a solid component a. a medical facility, or to be injected by a patient himself for home medical treatment, a dried or liquid medicine contained in a vial is dissolved with a fluid such as saline to make a medicinal solution which is then transferred to a syringe. A
syringe with a puncture needle or a tool having two hol low punc Lure needles at both ends, called a "double-ended needle", has been used for these operations. When the syringe with a needle is u:,ed, a rubber stopper in a mouth portion of a fluid container is pricked with the puncture needle to collect a predeter:~ined amount of .he fluid into the syringe and then, a rubber stopper in a mouth portion of a vial is pricked with the same needle to inject the fluid into the vial from the syringe. Then, the vial is shaken to dissolve the medicine with the fluff d and the rubber stopper is pricked arith the above needle again to col lect, a predetermined amount of the medicinal solution into the syringe .
When the "double-ended needle" is used, the rubber stopper of the vial filled wi th a dried medi cine is pric'.<ed with one puncture needle of the double-ended needle and the rubber stopper of the fluid container is pricked with another puncture needle, respective) y, which are located at both ends of the double-ended needle to communicate the vial with the fluid container. The fluid in the fluid container is transferred to the vial to dissolve the dried medicine, then, the fluid container and the double-ended needle are removed from the vial, and finally, the rubber stopper of the vial is pricked with a syringe with a needle likewise to collect a predetermined amount of the medicinal solution into the syringe.
These prior techniques involve a problem in that when the procedure of dissolving a dried medicine is carried out using the syringe with a needle, the procedure is complicated, the tip of the puncture needle riay be contaminated before use because the needle is exposed, and an operator may get injured by the tip of the needle when in use. When the double-ended needle is used and the need) a is pulled out or a predetermined amount of the medicinal solution is collected into the syringe, the operator may get injured by the t3.pS Of the needle, and the tips of the needle rnay be contaminated before the collection of the medicinal solution because the tips of the needle are exposed like the syringe with a needle. To solve the above problems, there is proposed an admixture injection adaptor which enables bcth injection and collection of a medicinal solution during a dissolution procedure (refer to JP 7-213525 A, paragraphs (,0008) to [0012), Fig. 1 and Fig. 2) In the admixture injection adagtor in this reference, a hollow puncture needle and a tubular tip fitting part, respectively, are set on opposite sides on the axis of a discoid hub, and a tubular vial fitting part which is concentrically ertended over the tip of the puncture needle and a tubular syringe fitting part which is concentrically emended over the tip of the tip fitting part are constructed on the outer edge of the hub. Theadaptor canconveniently transfer a medicinalsolution in a vial to a syringe after medicine in the vial is dissolved wish a fluid to prepare the medicinal solution while contamination of the tip of the needle or injury by the needle is avoided, ho;aever, the length of the skirt is limited so as to prevent the end of the skirt from contacting with the s'.~.oulder of the vial when the vial is pric',,ed with the needle, whereby the vial cannot be fitted straight and, therefore, a gap is formed between the rubber stopper of the vial and the needle to cause leakage of the medicinal solution during dissolution.
Summary of the Invention The present invention has been made in view of the above circumstances, and it is, therefore, an object of the present invention to provide a transfer needle assembly having the following advantages: dried medicine can be easily dissolved;
contamination of the tip of the needle and injury of an operator by the tip of the needle can be avoided; and leakage of a fluid from the transfer needle assembly during dissolution can be prevented.
in order to solve the above problems, the inventor of the present invention has carried out extensive studies. The inventor understood that it would be desirable that the tip of.
the puncture member be capable of sli ding froTn a position where the tin is receded in a skirt portion to a position where the tip projects from the skirt portion during transferring and injecting of a fluid, thereby reaching the present invention.
namely, the present invention relates to a transfer needle assembly comprising;
a cap-like guide member 1 having a top surface 11, a skirt por tion 13 and a tubular puncture needle insertion portion 12 penetrated tt-~rough the top surface 11 in the axial direction of the cap-like guide member 1; and a puncture member 2 comprising a tubular mer~aer provided Wlth a tip fitting portion 21 at the proximal end thereof for fitting a tip of a syringe and a puncture needle 22 at the distal end thereof to be inserted into the puncture needle insertion portion 12 of the cap-like guide member 1, and a filter portion 2 .-l crherein tr:e puncture needle 22 has a needle tip 223 and is provided with a gas passage 221 and a liquid passage 222;
and the liquid passage 222 communicates with the tip fitting portion 21 and the cas passage 221 is open to the outside through an air filter 231 in the filter portion 23, and wherein the puncture member 2 is fitted in the puncture needle insertion portion 12 of the cap-like guide mernber 1 in such a manner that the needle tip 223 of the puncture needle 22 in the puncture member 2 slides from a position where the needle tip 223 is receded in the skirt portion 13 to a position s~~here the needle tip 223 projects from the skirt portion 13.
Here, it is desirable that a cutout 1~ .s tormed in the skirt portion 13 of the guide membez 1 so that the puncture needle 22 ~rrhich recedes into the skirt portion i3 can be seen. A
dis'.~c-like, preferably sector disk-like collar 24 may also be provided athe p=oximal end of the puncture needle 22 to stop sliding in a forward direction of the puncture member 2 when the collar 29 comes in contact with the proximal end 122 of the puncture needle insertion portion 12 . It is also desirable shat the inner wail of the puncture needle insertion portion 12 is undercut to form a stepped portion 121 while retaining the proximal end portion thereof, an intermediate portion of the puncture needle 22 is provided with an annular projection 229, and the stepped portion 121 formed by undercutting engages with the annular proj ection 229 to stop slidi ng of the puncture member 2 in a backward direction.
Slide suppression means 32 for preventing accidental sliding of the puncture member 2 may also be provided between the collar 24 of the puncture rnember 2 and the top surface 11 of the guide member 1 . The slide suppression means is suitably a spring or a prop.
Erief Description of the Drawings Fig. 1 is a front view of an embodiment of the present invention.
Fig. 2 is a sectional view cut on line X-X of Fig. 1.
Fig. 3 is a longitudinal sectional view of another Arnbodiment of the present invention.
Fig. 4 is a front view of still another embodiment of the present invention.
Fig. 5 is a front sectional view of Fig.4.
Fig. 6 is a sectional view cut on line Y-Y of Fig. 9, Fig. 7 is a diagram for explaining use of the transfer needle assembly of the present invention.
Fig. 8 is a diagram for explaining use of the transfer needle assembly of the present invention.
The Most Preferred Embodiment of the Invention Preferred e~:bodiments of the present invention will be described with reference to the accompanying drawings.
As shoran in Figs. 1 to 6, the transfer needle assembly of the present invention includes a cap-like gui de member 1 ha wing atop surfacell, askirtportionl3andapunctureneedleinsertion portion 12; and a puncture member 2 f it ted in the punt Lure needle insertion portion 12 of the cap-like guide member 1 in such a nanner that a needle tip 223 of a puncture needle 22 in the puncture member 2 slides fromapositionwhere the needle tip 223 is receded into the skirt portion 13 to a position where the needle tip 223 projects from the skirt portion 13.
The guide menber 1 is generally a cap-like member formed from a plastic scch as polypropylene, polyethylene, polyester, polyvinyl chloride, polycarbonate or ABS resin and has the top surface 11, the skirt portion 13 and the tubular insertion portion i2 for puncture needle 22 penetrated through the top surface 11 in the axial direction of the transfer needle assembly. The s kirt portion 13 has an inner diameter that enables a mouth por tion of a vial (not shown) to slid~a along the inner wall thereof and a cutout i4 , formed on the distal end side thereof, for ident if ying the puncture needle 22 situated at a position where the needle is receded into the skirt portion 13. Aplurality of (generally 3 to 5) vertical ribs 15 which enable the mouth portion of the vial to slide smoothly are provided on the inner wall of the skirt portion 13. The vertical ribs 15 are undercut with their proximal end portions retained adjacent to the top surface 11, and stepped portions 151 formed by the undercutting come in contact w? th the mouth portion of the vial when the end 131 of the skirt portion 13 advances to a position where the end 131 contacts the shoulder portion of the vial.
The inner wall of the puncture needle insertion portion 2 is undercut with part of its proximal end retained and the puncture needle 22 of the puncture member 2 is inserted into this portion in such a manner that the puncture needls 22 can slide along the inner wall. Owing to this structure, thepuncture member 2 can recede up to a position where an annular rib 22A
of the puncture needle 22 to be described hereinart~r is engaged with a steppedportion 121 formedbythe undercutting. Therefore, the and=rcutting position. and the position of the annular rib 224 are determined such that the tip 223 of the puncture memi~er 2, that is, the tip 223 of the puncture needle 22, is receded into the skirt portion 13 when the annular rib 22a and the stepped portion ? 21 engage with each other (see, Fig. 7) . The puncture mernber 2 can advance up to a position where the proximal end 122 of the puncture needle insertion portion 12 comes in contact with a collar 29 of the puncture member 2 to be described hereinafter. Trerefore, the projecting length of the puncture needle insertion portion 12 from the top surface 11 is determined such that the tip 223 of the puncture member 2 projects from the skirt portion 13 when the proximal end 122 of the puncture needle insertion portion 12 comes in contact with the collar 24 of the puncture member 2 (see, Fig. 8).
The puncture member 2 is generally a tubular member formed from a plastic such as polypropylene, polyethylene, polyester, polycarbonate ~r P.BS resin anc3 a tip 223 of the puncture needle 22 is fitted in the puncture needle insertion portion 12 of the guide member 1 in such a manner that the tip 223 can slide from a position where the tip 223 is receded in the inside of the skirt portion 13 to a position where the tip 223 projects from the skirt portion 13. The puncture member 2 has, at the proximal end thereof, the tip fitting portion 21 into which a tip (not shown) of a syringe car. be mounted and, at ~he distal end thereof, the puncture needle 22 to be inserted into the puncture needle insertion portion 12.
S
In detail, the puncture member 2 is a tubular member having, at its proximal end, a tip fitting portion 21 and a puncture needle 22, at its distal end, to be insertedinto the above puncture needle insertion portion 12 and which also has a filter portion 23. The tip fitting portion 21 comprises a cylindrical area for accommodating a syringe and for mounting a tip of the syringe and an aperture on the bottom. The aperture is preferably, crescent, semicircular, elliptical or circular, but is not limitedto these shapes . The puncture needle 22 includes a tubular outer wail of which a proximal end is partly connected with the bottom of the tip fitting portion 21, but the remaining proximal part is connected with the filter portion 23, and a needle shaped septum continues, from the aperture of the tip fitting portion 21. The outer wall and the septum form a liquid passage from the tip fitting portion 21 to the guide member 1 and a gas passage from the filter portion 23 to the guide member 1. The cross-sectional zrea of the liquid passage is preferably, crescent, semicircular, elliptical or circular, and the cross-sectional area of the gas passage is, preferably, ci rcular.
The length of the septum is longer than the length of the outer wall of the puncture needle, and the distal end of the outer wall of the gas passage extends dawnwardly beyond the dital end of the outer wall of the ? iquid passage in order to prevent l0 the air introduced into the vial from returning to the syringe.
The filter portion 23 is located outside of the tip fitting portion 12 and connected with the outer wall of the puncture needle 22 and is provided with an air filter 231 at the proximal end of the gas passage. The filter portion 23 preferably, lccates in a position where a lock~typed syringe is not contact the tip fitting portion 21 and further, a position where the movements of the disk-like collar 2G and thepuneture needle fitting portion .2 are not disturbed when the collar 24 comes in contact with the puncture needle fitting portion 12. The filter portion 23 is, preferably, a cylindrical portion extending from the outside ~f the tip fitting portion 21 and the outer wall of the puncture needle 22, but is not limited to this shap=_.
That is, the puncture needle 22 is pro~rided with a liquid passage 222 which con~cnunicates with the tip fitting portion 21 and a gas passage 221 whi ch communicates with the outside through an air filter 231 in the filter portion 23.
The gas passage 221 enables outside air to be introduced into the mouth portion of the vial via the air filter 231 in the filter portion 23 and the liquid passage 222 enabl es a f 1 uid tc be injected into the mouth of the vial through the tip 223.
The liauid passage 222 communicates with the tip fitting portion 21, and the gas passage 221 is open to .tr:e outside through the air filter 231 of the filter portion 23 which communicates with the gas passage 221.
The vial filled with a medicine such as a biological agent usually has a reduced pressure on the inside cahile freeze-drying the mQdicine. When a syringe filled with a dissolution fluid such as saline is connected with the vial by means of the transfer needle assembly, outside air is introduced into the vial in order to release the reduced pressure. The filter portion 23 is provided ~.n the gas passage 221 to prevent the air contami nation via the air fi7.ter 231. In case of a syringe filled with a dissolution fluid and connected with the tig fitting portion 21, air is also introduced into the vial when the dissolution f l uid is introduced into the vial containing a dried medicine and mired to prepare the medicinal solution, anti thp solution is returned back into thp syringe again.
Tn the present invention, for example, a disk-like, preferably, sector disk-like, collar 24 may be provided at the proximal end of the puncture needle 22 so that tr:e collar 24 comes in contact with the proximal end 122 of the puncture needle ins=rtionportior. 12 at apositionwher~ the tip 2230 the puncture member 2 projects from the skirt porticn 13 to step the sliding of the puncture member 2 in a forward direction of the puncture member 2.
The intermediate portion of the puncture needle 22 is provided with the annular rib 229 which is engagedwith the stepped portion 121 of the puncture needle insertion portion 12 at a position where the tip 223 of the puncture member 2 is receded into the skirt portion 13 to stop the sliding of the puncture member 2 in a backward direction of the puncture member 2.
To prevent the puncture member 2 from sliding acciden tally, slide suppressing means may be provided between the collar 24 of the puncture member 2 and the top surface 1I of the guide member 1. The slide suppressing means is suitably a spring 32 as shown in Figs. 4 to 6 or a prop 31 having a corset function as shown in Fig. 3.
A description is given below of use of the transfer needle assembly of the present invention with reference to Fig. 7 and Fig. 8.
As sho~~rn in Fig. 7, a transfer needle assembly T~1 and a ;rial V are first prepared. The tip 223 of the puncture needle 22 is situated within the skirt portion 13. The skirt portion .3 is applied to the mouth portion M of the vial V, the whole transfer needle assembly TAI is pressed down straigh4, a rubber i~
stopper P,S is pricked with the puncture needle 22, and the forward movement of the transfer needle assembly TN is stopped at a position where the puncture needle insertion portion 12 comes in contact with the sector disk-like collar 29 . At this point.
the stepped portion 151 engages the mouth portion M of the vial V, and the inside of the vial V communicates with the outside air and the tip fitting portion 21 through the gas passage 221 and the liquid passage 222 or the puncture needle 22, respectively (see Fig. 8) . When the tip fitting portion 21 is connected to a syringe (not shown) fill ed with the fluid in this state, the dissolute on procedure can be easily carried vut by introducing the fluid in the syringe into the mouth portion M of the vial V.
As obvious frorn the above description, by using the present invention, the dissolution procedure can be easily carried out.
Contamination of the tip of the needle and injury by the tip o' the needle can be avoided and leakage of a liquid during the dissolution orocedure can be prevented.
Field of the Invention The present invent ion relates to a transfer needle assembly for transferring fluid from a fluid source to a vial contairLing a solid :nat~rial or a liquid material. The transfer needle assembly of the present invention eliminates problems such as contamination of a tip of a puncture needle in the transfer needle assembly before use and inj ury to an operator' s f l nger by the tip of the puncture needle and flu? d leakage from the transfer needle assembly when in use.
Background of th=_ Tnvention In order to prepare a Iiquidmedical component for adhering tissues in a living body or to be mixed with a solid component a. a medical facility, or to be injected by a patient himself for home medical treatment, a dried or liquid medicine contained in a vial is dissolved with a fluid such as saline to make a medicinal solution which is then transferred to a syringe. A
syringe with a puncture needle or a tool having two hol low punc Lure needles at both ends, called a "double-ended needle", has been used for these operations. When the syringe with a needle is u:,ed, a rubber stopper in a mouth portion of a fluid container is pricked with the puncture needle to collect a predeter:~ined amount of .he fluid into the syringe and then, a rubber stopper in a mouth portion of a vial is pricked with the same needle to inject the fluid into the vial from the syringe. Then, the vial is shaken to dissolve the medicine with the fluff d and the rubber stopper is pricked arith the above needle again to col lect, a predetermined amount of the medicinal solution into the syringe .
When the "double-ended needle" is used, the rubber stopper of the vial filled wi th a dried medi cine is pric'.<ed with one puncture needle of the double-ended needle and the rubber stopper of the fluid container is pricked with another puncture needle, respective) y, which are located at both ends of the double-ended needle to communicate the vial with the fluid container. The fluid in the fluid container is transferred to the vial to dissolve the dried medicine, then, the fluid container and the double-ended needle are removed from the vial, and finally, the rubber stopper of the vial is pricked with a syringe with a needle likewise to collect a predetermined amount of the medicinal solution into the syringe.
These prior techniques involve a problem in that when the procedure of dissolving a dried medicine is carried out using the syringe with a needle, the procedure is complicated, the tip of the puncture needle riay be contaminated before use because the needle is exposed, and an operator may get injured by the tip of the needle when in use. When the double-ended needle is used and the need) a is pulled out or a predetermined amount of the medicinal solution is collected into the syringe, the operator may get injured by the t3.pS Of the needle, and the tips of the needle rnay be contaminated before the collection of the medicinal solution because the tips of the needle are exposed like the syringe with a needle. To solve the above problems, there is proposed an admixture injection adaptor which enables bcth injection and collection of a medicinal solution during a dissolution procedure (refer to JP 7-213525 A, paragraphs (,0008) to [0012), Fig. 1 and Fig. 2) In the admixture injection adagtor in this reference, a hollow puncture needle and a tubular tip fitting part, respectively, are set on opposite sides on the axis of a discoid hub, and a tubular vial fitting part which is concentrically ertended over the tip of the puncture needle and a tubular syringe fitting part which is concentrically emended over the tip of the tip fitting part are constructed on the outer edge of the hub. Theadaptor canconveniently transfer a medicinalsolution in a vial to a syringe after medicine in the vial is dissolved wish a fluid to prepare the medicinal solution while contamination of the tip of the needle or injury by the needle is avoided, ho;aever, the length of the skirt is limited so as to prevent the end of the skirt from contacting with the s'.~.oulder of the vial when the vial is pric',,ed with the needle, whereby the vial cannot be fitted straight and, therefore, a gap is formed between the rubber stopper of the vial and the needle to cause leakage of the medicinal solution during dissolution.
Summary of the Invention The present invention has been made in view of the above circumstances, and it is, therefore, an object of the present invention to provide a transfer needle assembly having the following advantages: dried medicine can be easily dissolved;
contamination of the tip of the needle and injury of an operator by the tip of the needle can be avoided; and leakage of a fluid from the transfer needle assembly during dissolution can be prevented.
in order to solve the above problems, the inventor of the present invention has carried out extensive studies. The inventor understood that it would be desirable that the tip of.
the puncture member be capable of sli ding froTn a position where the tin is receded in a skirt portion to a position where the tip projects from the skirt portion during transferring and injecting of a fluid, thereby reaching the present invention.
namely, the present invention relates to a transfer needle assembly comprising;
a cap-like guide member 1 having a top surface 11, a skirt por tion 13 and a tubular puncture needle insertion portion 12 penetrated tt-~rough the top surface 11 in the axial direction of the cap-like guide member 1; and a puncture member 2 comprising a tubular mer~aer provided Wlth a tip fitting portion 21 at the proximal end thereof for fitting a tip of a syringe and a puncture needle 22 at the distal end thereof to be inserted into the puncture needle insertion portion 12 of the cap-like guide member 1, and a filter portion 2 .-l crherein tr:e puncture needle 22 has a needle tip 223 and is provided with a gas passage 221 and a liquid passage 222;
and the liquid passage 222 communicates with the tip fitting portion 21 and the cas passage 221 is open to the outside through an air filter 231 in the filter portion 23, and wherein the puncture member 2 is fitted in the puncture needle insertion portion 12 of the cap-like guide mernber 1 in such a manner that the needle tip 223 of the puncture needle 22 in the puncture member 2 slides from a position where the needle tip 223 is receded in the skirt portion 13 to a position s~~here the needle tip 223 projects from the skirt portion 13.
Here, it is desirable that a cutout 1~ .s tormed in the skirt portion 13 of the guide membez 1 so that the puncture needle 22 ~rrhich recedes into the skirt portion i3 can be seen. A
dis'.~c-like, preferably sector disk-like collar 24 may also be provided athe p=oximal end of the puncture needle 22 to stop sliding in a forward direction of the puncture member 2 when the collar 29 comes in contact with the proximal end 122 of the puncture needle insertion portion 12 . It is also desirable shat the inner wail of the puncture needle insertion portion 12 is undercut to form a stepped portion 121 while retaining the proximal end portion thereof, an intermediate portion of the puncture needle 22 is provided with an annular projection 229, and the stepped portion 121 formed by undercutting engages with the annular proj ection 229 to stop slidi ng of the puncture member 2 in a backward direction.
Slide suppression means 32 for preventing accidental sliding of the puncture member 2 may also be provided between the collar 24 of the puncture rnember 2 and the top surface 11 of the guide member 1 . The slide suppression means is suitably a spring or a prop.
Erief Description of the Drawings Fig. 1 is a front view of an embodiment of the present invention.
Fig. 2 is a sectional view cut on line X-X of Fig. 1.
Fig. 3 is a longitudinal sectional view of another Arnbodiment of the present invention.
Fig. 4 is a front view of still another embodiment of the present invention.
Fig. 5 is a front sectional view of Fig.4.
Fig. 6 is a sectional view cut on line Y-Y of Fig. 9, Fig. 7 is a diagram for explaining use of the transfer needle assembly of the present invention.
Fig. 8 is a diagram for explaining use of the transfer needle assembly of the present invention.
The Most Preferred Embodiment of the Invention Preferred e~:bodiments of the present invention will be described with reference to the accompanying drawings.
As shoran in Figs. 1 to 6, the transfer needle assembly of the present invention includes a cap-like gui de member 1 ha wing atop surfacell, askirtportionl3andapunctureneedleinsertion portion 12; and a puncture member 2 f it ted in the punt Lure needle insertion portion 12 of the cap-like guide member 1 in such a nanner that a needle tip 223 of a puncture needle 22 in the puncture member 2 slides fromapositionwhere the needle tip 223 is receded into the skirt portion 13 to a position where the needle tip 223 projects from the skirt portion 13.
The guide menber 1 is generally a cap-like member formed from a plastic scch as polypropylene, polyethylene, polyester, polyvinyl chloride, polycarbonate or ABS resin and has the top surface 11, the skirt portion 13 and the tubular insertion portion i2 for puncture needle 22 penetrated through the top surface 11 in the axial direction of the transfer needle assembly. The s kirt portion 13 has an inner diameter that enables a mouth por tion of a vial (not shown) to slid~a along the inner wall thereof and a cutout i4 , formed on the distal end side thereof, for ident if ying the puncture needle 22 situated at a position where the needle is receded into the skirt portion 13. Aplurality of (generally 3 to 5) vertical ribs 15 which enable the mouth portion of the vial to slide smoothly are provided on the inner wall of the skirt portion 13. The vertical ribs 15 are undercut with their proximal end portions retained adjacent to the top surface 11, and stepped portions 151 formed by the undercutting come in contact w? th the mouth portion of the vial when the end 131 of the skirt portion 13 advances to a position where the end 131 contacts the shoulder portion of the vial.
The inner wall of the puncture needle insertion portion 2 is undercut with part of its proximal end retained and the puncture needle 22 of the puncture member 2 is inserted into this portion in such a manner that the puncture needls 22 can slide along the inner wall. Owing to this structure, thepuncture member 2 can recede up to a position where an annular rib 22A
of the puncture needle 22 to be described hereinart~r is engaged with a steppedportion 121 formedbythe undercutting. Therefore, the and=rcutting position. and the position of the annular rib 224 are determined such that the tip 223 of the puncture memi~er 2, that is, the tip 223 of the puncture needle 22, is receded into the skirt portion 13 when the annular rib 22a and the stepped portion ? 21 engage with each other (see, Fig. 7) . The puncture mernber 2 can advance up to a position where the proximal end 122 of the puncture needle insertion portion 12 comes in contact with a collar 29 of the puncture member 2 to be described hereinafter. Trerefore, the projecting length of the puncture needle insertion portion 12 from the top surface 11 is determined such that the tip 223 of the puncture member 2 projects from the skirt portion 13 when the proximal end 122 of the puncture needle insertion portion 12 comes in contact with the collar 24 of the puncture member 2 (see, Fig. 8).
The puncture member 2 is generally a tubular member formed from a plastic such as polypropylene, polyethylene, polyester, polycarbonate ~r P.BS resin anc3 a tip 223 of the puncture needle 22 is fitted in the puncture needle insertion portion 12 of the guide member 1 in such a manner that the tip 223 can slide from a position where the tip 223 is receded in the inside of the skirt portion 13 to a position where the tip 223 projects from the skirt portion 13. The puncture member 2 has, at the proximal end thereof, the tip fitting portion 21 into which a tip (not shown) of a syringe car. be mounted and, at ~he distal end thereof, the puncture needle 22 to be inserted into the puncture needle insertion portion 12.
S
In detail, the puncture member 2 is a tubular member having, at its proximal end, a tip fitting portion 21 and a puncture needle 22, at its distal end, to be insertedinto the above puncture needle insertion portion 12 and which also has a filter portion 23. The tip fitting portion 21 comprises a cylindrical area for accommodating a syringe and for mounting a tip of the syringe and an aperture on the bottom. The aperture is preferably, crescent, semicircular, elliptical or circular, but is not limitedto these shapes . The puncture needle 22 includes a tubular outer wail of which a proximal end is partly connected with the bottom of the tip fitting portion 21, but the remaining proximal part is connected with the filter portion 23, and a needle shaped septum continues, from the aperture of the tip fitting portion 21. The outer wall and the septum form a liquid passage from the tip fitting portion 21 to the guide member 1 and a gas passage from the filter portion 23 to the guide member 1. The cross-sectional zrea of the liquid passage is preferably, crescent, semicircular, elliptical or circular, and the cross-sectional area of the gas passage is, preferably, ci rcular.
The length of the septum is longer than the length of the outer wall of the puncture needle, and the distal end of the outer wall of the gas passage extends dawnwardly beyond the dital end of the outer wall of the ? iquid passage in order to prevent l0 the air introduced into the vial from returning to the syringe.
The filter portion 23 is located outside of the tip fitting portion 12 and connected with the outer wall of the puncture needle 22 and is provided with an air filter 231 at the proximal end of the gas passage. The filter portion 23 preferably, lccates in a position where a lock~typed syringe is not contact the tip fitting portion 21 and further, a position where the movements of the disk-like collar 2G and thepuneture needle fitting portion .2 are not disturbed when the collar 24 comes in contact with the puncture needle fitting portion 12. The filter portion 23 is, preferably, a cylindrical portion extending from the outside ~f the tip fitting portion 21 and the outer wall of the puncture needle 22, but is not limited to this shap=_.
That is, the puncture needle 22 is pro~rided with a liquid passage 222 which con~cnunicates with the tip fitting portion 21 and a gas passage 221 whi ch communicates with the outside through an air filter 231 in the filter portion 23.
The gas passage 221 enables outside air to be introduced into the mouth portion of the vial via the air filter 231 in the filter portion 23 and the liquid passage 222 enabl es a f 1 uid tc be injected into the mouth of the vial through the tip 223.
The liauid passage 222 communicates with the tip fitting portion 21, and the gas passage 221 is open to .tr:e outside through the air filter 231 of the filter portion 23 which communicates with the gas passage 221.
The vial filled with a medicine such as a biological agent usually has a reduced pressure on the inside cahile freeze-drying the mQdicine. When a syringe filled with a dissolution fluid such as saline is connected with the vial by means of the transfer needle assembly, outside air is introduced into the vial in order to release the reduced pressure. The filter portion 23 is provided ~.n the gas passage 221 to prevent the air contami nation via the air fi7.ter 231. In case of a syringe filled with a dissolution fluid and connected with the tig fitting portion 21, air is also introduced into the vial when the dissolution f l uid is introduced into the vial containing a dried medicine and mired to prepare the medicinal solution, anti thp solution is returned back into thp syringe again.
Tn the present invention, for example, a disk-like, preferably, sector disk-like, collar 24 may be provided at the proximal end of the puncture needle 22 so that tr:e collar 24 comes in contact with the proximal end 122 of the puncture needle ins=rtionportior. 12 at apositionwher~ the tip 2230 the puncture member 2 projects from the skirt porticn 13 to step the sliding of the puncture member 2 in a forward direction of the puncture member 2.
The intermediate portion of the puncture needle 22 is provided with the annular rib 229 which is engagedwith the stepped portion 121 of the puncture needle insertion portion 12 at a position where the tip 223 of the puncture member 2 is receded into the skirt portion 13 to stop the sliding of the puncture member 2 in a backward direction of the puncture member 2.
To prevent the puncture member 2 from sliding acciden tally, slide suppressing means may be provided between the collar 24 of the puncture member 2 and the top surface 1I of the guide member 1. The slide suppressing means is suitably a spring 32 as shown in Figs. 4 to 6 or a prop 31 having a corset function as shown in Fig. 3.
A description is given below of use of the transfer needle assembly of the present invention with reference to Fig. 7 and Fig. 8.
As sho~~rn in Fig. 7, a transfer needle assembly T~1 and a ;rial V are first prepared. The tip 223 of the puncture needle 22 is situated within the skirt portion 13. The skirt portion .3 is applied to the mouth portion M of the vial V, the whole transfer needle assembly TAI is pressed down straigh4, a rubber i~
stopper P,S is pricked with the puncture needle 22, and the forward movement of the transfer needle assembly TN is stopped at a position where the puncture needle insertion portion 12 comes in contact with the sector disk-like collar 29 . At this point.
the stepped portion 151 engages the mouth portion M of the vial V, and the inside of the vial V communicates with the outside air and the tip fitting portion 21 through the gas passage 221 and the liquid passage 222 or the puncture needle 22, respectively (see Fig. 8) . When the tip fitting portion 21 is connected to a syringe (not shown) fill ed with the fluid in this state, the dissolute on procedure can be easily carried vut by introducing the fluid in the syringe into the mouth portion M of the vial V.
As obvious frorn the above description, by using the present invention, the dissolution procedure can be easily carried out.
Contamination of the tip of the needle and injury by the tip o' the needle can be avoided and leakage of a liquid during the dissolution orocedure can be prevented.
Claims (8)
1. A transfer needle assembly comprising a cap-like guide member 1 having a top surface 11, a skirt portion 13 and a tubular puncture needle insertion portion 12 penetrated through the top surface 11 in an axial direction of the cap-like guide member 1; and a puncture member 2 comprising a tubular member provided with a tip fitting portion 21 at a proximal end thereof for fitting a tip of a syringe and a puncture needle 22 at the distal end thereof to be inserted into the puncture needle insertion portion 12 of the cap-like guide member 1, and a filter portion 23;
wherein the puncture needle 22 has a needle tip 223 and is provided with a gas passage 221 and a liquid passage 222;
and the liquid passage 222 communicates with the tip fitting portion 21 and the gas passage 221 is open to the outside through an air filter 231 in the filter portion 23, and wherein the puncture member 2 is fitted in the puncture needle insertion portion 12 of the cap-like guide member 1 in such a manner that the needle tip 223 of the puncture needle 22 in the puncture member 2 slides from a position where the needle tip 223 is receded into the skirt portion 13 to a position where the needle tip 223 projects from the skirt portion 13.
wherein the puncture needle 22 has a needle tip 223 and is provided with a gas passage 221 and a liquid passage 222;
and the liquid passage 222 communicates with the tip fitting portion 21 and the gas passage 221 is open to the outside through an air filter 231 in the filter portion 23, and wherein the puncture member 2 is fitted in the puncture needle insertion portion 12 of the cap-like guide member 1 in such a manner that the needle tip 223 of the puncture needle 22 in the puncture member 2 slides from a position where the needle tip 223 is receded into the skirt portion 13 to a position where the needle tip 223 projects from the skirt portion 13.
2. The transfer needle assembly according to claim 1, wherein a cutout 14 is formed in the skirt portion 13 of the cap-like guide member 1 so that the needle tip 223 of the puncture needle 22 which is receded into the skirt portion 13 can be seen.
3. The transfer needle assembly according to claim 1, wherein a disk-like collar 24 is provided at the proximal end of the puncture needle 22 to stop sliding of the puncture member 2 in a forward direction of the puncture member 2 when the collar 24 comes in contact wish the proximal end 122 of the puncture needle insertion portion 12.
4. The transfer needle assembly according to claims 1, wherein an inner wall of the puncture needle insertion portion 12 is undercut to form a stepped portion 121 at a proximal end thereof, an intermediate portion of the puncture needle 22 is provided with an annular projection 225, and the stepped portion 121 formed by undercutting is engageable with the annular projection 224 to stop sliding of the puncture member 2 in a backward direction of the puncture member 2.
5. The transfer needle assembly according to claim 1, wherein a disk-like collar 29 is provided at the proximal end of the puncture needle 22 to stop sliding in a forward direction of the puncture member 2 when the collar 29 comes in contact with the proximal end 122 of the puncture needle insertion portion 12, and wherein an inner wall of the puncture needle insertion portion 12 is undercut to form a stepped portion 121 at a proximal end thereof, an intermediate portion of the puncture needle 22 is provided with an annular projection 224, and the stepped portion 121 formed by undercutting is engageable with the annular projection 224 to stop sliding of the puncture member 2 in a backward direction of the puncture member 2.
6. The transfer needle assembly according to claim 1, wherein a slide suppression means 32 for presenting accidental sliding of the puncture member 2 is provided between the collar 24 of the puncture member 2 and the top surface 11 of the guide member 1.
7. The transfer needle assembly according to claim 6, wherein the slide suppression means 32 is a spring.
8. The transfer needle assembly according to claim 6, wherein the slide suppression means 32 is a prop.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002-259227 | 2002-09-04 | ||
| JP2002259227A JP2004097253A (en) | 2002-09-04 | 2002-09-04 | Liquid transfusion device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2438760A1 true CA2438760A1 (en) | 2004-03-04 |
Family
ID=31712312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2438760 Abandoned CA2438760A1 (en) | 2002-09-04 | 2003-08-29 | Transfert needle assembly |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20040044327A1 (en) |
| EP (1) | EP1396250B1 (en) |
| JP (1) | JP2004097253A (en) |
| CA (1) | CA2438760A1 (en) |
| DE (1) | DE60335846D1 (en) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL114960A0 (en) | 1995-03-20 | 1995-12-08 | Medimop Medical Projects Ltd | Flow control device |
| US6989891B2 (en) | 2001-11-08 | 2006-01-24 | Optiscan Biomedical Corporation | Device and method for in vitro determination of analyte concentrations within body fluids |
| IL161660A0 (en) | 2004-04-29 | 2004-09-27 | Medimop Medical Projects Ltd | Liquid drug delivery device |
| DK1919432T3 (en) * | 2005-08-11 | 2012-01-30 | Medimop Medical Projects Ltd | Liquid Medication Transfer Devices for Safe Safe Resting Connection on Medical Vials |
| US7896859B2 (en) * | 2005-10-20 | 2011-03-01 | Tyco Healthcare Group Lp | Enteral feeding set |
| CA2834152C (en) * | 2006-05-25 | 2016-07-05 | Bayer Healthcare Llc | Reconstitution device |
| US8002756B2 (en) | 2006-12-08 | 2011-08-23 | Becton, Dickinson And Company | Method and apparatus for delivering a therapeutic substance through an injection port |
| IL182605A0 (en) | 2007-04-17 | 2007-07-24 | Medimop Medical Projects Ltd | Fluid control device with manually depressed actuator |
| WO2008144575A2 (en) | 2007-05-18 | 2008-11-27 | Optiscan Biomedical Corporation | Fluid injection and safety system |
| EP2188004A4 (en) * | 2007-08-21 | 2015-06-17 | Yukon Medical Llc | Vial access and injection system |
| CN101918074B (en) | 2007-09-18 | 2013-02-27 | 麦迪麦珀医疗工程有限公司 | Medicament mixing and injection apparatus |
| IL186290A0 (en) | 2007-09-25 | 2008-01-20 | Medimop Medical Projects Ltd | Liquid drug delivery devices for use with syringe having widened distal tip |
| DE102007061346A1 (en) * | 2007-12-17 | 2009-06-18 | Bayer Schering Pharma Aktiengesellschaft | Spike with two thorns |
| US8141601B2 (en) * | 2008-10-02 | 2012-03-27 | Roche Diagnostics Operations, Inc. | Manual filling aid with push button fill |
| JP5432176B2 (en) | 2008-11-21 | 2014-03-05 | テルモ株式会社 | Connector |
| JP5495006B2 (en) * | 2008-11-25 | 2014-05-21 | 株式会社ジェイ・エム・エス | connector |
| USD641080S1 (en) | 2009-03-31 | 2011-07-05 | Medimop Medical Projects Ltd. | Medical device having syringe port with locking mechanism |
| USD616984S1 (en) | 2009-07-02 | 2010-06-01 | Medimop Medical Projects Ltd. | Vial adapter having side windows |
| USD630732S1 (en) | 2009-09-29 | 2011-01-11 | Medimop Medical Projects Ltd. | Vial adapter with female connector |
| IL201323A0 (en) | 2009-10-01 | 2010-05-31 | Medimop Medical Projects Ltd | Fluid transfer device for assembling a vial with pre-attached female connector |
| IL202069A0 (en) | 2009-11-12 | 2010-06-16 | Medimop Medical Projects Ltd | Fluid transfer device with sealing arrangement |
| IL202070A0 (en) | 2009-11-12 | 2010-06-16 | Medimop Medical Projects Ltd | Inline liquid drug medical device |
| BR112012021134B1 (en) | 2010-02-24 | 2020-01-21 | Medimop Medical Projects Ltd | fluid transfer set for use with a first vial and a second vial for reconstitution and liquid drug delivery |
| CN102781396B (en) | 2010-02-24 | 2015-01-07 | 麦迪麦珀医疗工程有限公司 | Liquid drug transfer device with vented vial adapter |
| USD669980S1 (en) | 2010-10-15 | 2012-10-30 | Medimop Medical Projects Ltd. | Vented vial adapter |
| IL209290A0 (en) | 2010-11-14 | 2011-01-31 | Medimop Medical Projects Ltd | Inline liquid drug medical device having rotary flow control member |
| IL212420A0 (en) | 2011-04-17 | 2011-06-30 | Medimop Medical Projects Ltd | Liquid drug transfer assembly |
| IL215699A0 (en) | 2011-10-11 | 2011-12-29 | Medimop Medical Projects Ltd | Liquid drug reconstitution assemblage for use with iv bag and drug vial |
| USD674088S1 (en) | 2012-02-13 | 2013-01-08 | Medimop Medical Projects Ltd. | Vial adapter |
| USD737436S1 (en) | 2012-02-13 | 2015-08-25 | Medimop Medical Projects Ltd. | Liquid drug reconstitution assembly |
| USD720451S1 (en) | 2012-02-13 | 2014-12-30 | Medimop Medical Projects Ltd. | Liquid drug transfer assembly |
| IL219065A0 (en) | 2012-04-05 | 2012-07-31 | Medimop Medical Projects Ltd | Fluid transfer device with manual operated cartridge release arrangement |
| US11014696B2 (en) * | 2017-07-12 | 2021-05-25 | Vanrx Pharmasystems Inc. | Purgeable pharmaceutical fill needle |
| USD769444S1 (en) * | 2012-06-28 | 2016-10-18 | Yukon Medical, Llc | Adapter device |
| IL221634A0 (en) | 2012-08-26 | 2012-12-31 | Medimop Medical Projects Ltd | Universal drug vial adapter |
| IL221635A0 (en) | 2012-08-26 | 2012-12-31 | Medimop Medical Projects Ltd | Drug vial mixing and transfer device for use with iv bag and drug vial |
| EP2872100B1 (en) | 2012-09-13 | 2017-03-29 | Medimop Medical Projects Ltd | Telescopic female drug vial adapter |
| USD734868S1 (en) | 2012-11-27 | 2015-07-21 | Medimop Medical Projects Ltd. | Drug vial adapter with downwardly depending stopper |
| US9101717B2 (en) * | 2013-03-12 | 2015-08-11 | Carefusion 303, Inc. | Non-vented vial access syringe |
| IL225734A0 (en) | 2013-04-14 | 2013-09-30 | Medimop Medical Projects Ltd | Ready-to-use drug vial assemblages including drug vial and drug vial closure having fluid transfer member, and drug vial closure therefor |
| JP6199483B2 (en) | 2013-05-10 | 2017-09-20 | メディモップ・メディカル・プロジェクツ・リミテッド | Medical device comprising a vial adapter having an in-line dry drug module |
| USD765837S1 (en) | 2013-08-07 | 2016-09-06 | Medimop Medical Projects Ltd. | Liquid transfer device with integral vial adapter |
| CN205626622U (en) | 2013-08-07 | 2016-10-12 | 麦迪麦珀医疗工程有限公司 | Liquid transfer device that is used together with infusion container |
| USD767124S1 (en) | 2013-08-07 | 2016-09-20 | Medimop Medical Projects Ltd. | Liquid transfer device with integral vial adapter |
| USD757933S1 (en) | 2014-09-11 | 2016-05-31 | Medimop Medical Projects Ltd. | Dual vial adapter assemblage |
| WO2016110838A1 (en) | 2015-01-05 | 2016-07-14 | Medimop Medical Projects Ltd | Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage |
| CN113143759B (en) | 2015-07-16 | 2024-01-30 | 西部制药服务以色列有限公司 | Liquid drug transfer device for secure telescopic snap-fit on an injection vial |
| USD801522S1 (en) | 2015-11-09 | 2017-10-31 | Medimop Medical Projects Ltd. | Fluid transfer assembly |
| CN108366905A (en) | 2015-11-25 | 2018-08-03 | 西部制药服务以色列有限公司 | Include double bottle commutator components of the vial adapter of the inlet valve with automatic-sealed |
| IL245800A0 (en) | 2016-05-24 | 2016-08-31 | West Pharma Services Il Ltd | Dual vial adapter assemblages including identical twin vial adapters |
| IL245803A0 (en) | 2016-05-24 | 2016-08-31 | West Pharma Services Il Ltd | Dual vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter |
| IL246073A0 (en) | 2016-06-06 | 2016-08-31 | West Pharma Services Il Ltd | Fluid transfer devices for use with drug pump cartridge having slidable driving plunger |
| IL247376A0 (en) | 2016-08-21 | 2016-12-29 | Medimop Medical Projects Ltd | Syringe assembly |
| USD832430S1 (en) | 2016-11-15 | 2018-10-30 | West Pharma. Services IL, Ltd. | Dual vial adapter assemblage |
| IL249408A0 (en) | 2016-12-06 | 2017-03-30 | Medimop Medical Projects Ltd | Liquid transfer device for use with infusion liquid container and pincers-like hand tool for use therewith for releasing intact drug vial therefrom |
| IL251458A0 (en) | 2017-03-29 | 2017-06-29 | Medimop Medical Projects Ltd | User actuated liquid drug transfer devices for use in ready-to-use (rtu) liquid drug transfer assemblages |
| IL254802A0 (en) | 2017-09-29 | 2017-12-31 | Medimop Medical Projects Ltd | Dual vial adapter assemblages with twin vented female vial adapters |
| USD903864S1 (en) | 2018-06-20 | 2020-12-01 | West Pharma. Services IL, Ltd. | Medication mixing apparatus |
| JP1630477S (en) | 2018-07-06 | 2019-05-07 | ||
| USD923812S1 (en) | 2019-01-16 | 2021-06-29 | West Pharma. Services IL, Ltd. | Medication mixing apparatus |
| JP1648075S (en) | 2019-01-17 | 2019-12-16 | ||
| JP7101900B2 (en) | 2019-01-31 | 2022-07-15 | ウェスト・ファーマ・サービシーズ・アイエル・リミテッド | Liquid transfer device |
| IL277446B2 (en) | 2019-04-30 | 2024-02-01 | West Pharma Services Il Ltd | Liquid transfer device with dual lumen iv spike |
| CN110897883A (en) * | 2019-12-20 | 2020-03-24 | 山西医科大学 | Liquid pumping adapter and constant-pressure liquid pumping device |
| USD956958S1 (en) | 2020-07-13 | 2022-07-05 | West Pharma. Services IL, Ltd. | Liquid transfer device |
| CN112774746B (en) * | 2020-12-29 | 2022-11-15 | 深圳市天林智能科学仪器有限公司 | Automatic processing workstation of waste liquid in organic test vial |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0165926B1 (en) * | 1983-05-20 | 1990-10-24 | Bengt Gustavsson | A device for transferring a substance |
| IT1173370B (en) * | 1984-02-24 | 1987-06-24 | Erba Farmitalia | SAFETY DEVICE TO CONNECT A SYRINGE TO THE MOUTH OF A BOTTLE CONTAINING A DRUG OR A TUBE FOR DISPENSING THE SYRINGE DRUG |
| ES2059822T3 (en) * | 1988-06-02 | 1994-11-16 | Piero Marrucchi | METHOD AND APPARATUS FOR HANDLING AND TRANSFERING PRODUCTS AMONG REDUCED VOLUMES. |
| JP3475414B2 (en) | 1994-01-28 | 2003-12-08 | ニプロ株式会社 | Adapter for co-infusion |
| FR2753624B1 (en) * | 1996-09-25 | 1999-04-16 | Biodome | CONNECTION DEVICE, PARTICULARLY BETWEEN A CONTAINER WITH PERFORABLE CAP AND A SYRINGE |
| US6378714B1 (en) * | 1998-04-20 | 2002-04-30 | Becton Dickinson And Company | Transferset for vials and other medical containers |
| US6358236B1 (en) * | 1998-08-06 | 2002-03-19 | Baxter International Inc. | Device for reconstituting medicaments for injection |
| US6453956B2 (en) * | 1999-11-05 | 2002-09-24 | Medtronic Minimed, Inc. | Needle safe transfer guard |
| JP4372310B2 (en) * | 2000-04-10 | 2009-11-25 | ニプロ株式会社 | Adapter for mixed injection |
-
2002
- 2002-09-04 JP JP2002259227A patent/JP2004097253A/en active Pending
-
2003
- 2003-08-29 CA CA 2438760 patent/CA2438760A1/en not_active Abandoned
- 2003-09-02 US US10/652,512 patent/US20040044327A1/en not_active Abandoned
- 2003-09-03 DE DE60335846T patent/DE60335846D1/en not_active Expired - Lifetime
- 2003-09-03 EP EP20030019584 patent/EP1396250B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60335846D1 (en) | 2011-03-10 |
| EP1396250B1 (en) | 2011-01-26 |
| US20040044327A1 (en) | 2004-03-04 |
| JP2004097253A (en) | 2004-04-02 |
| EP1396250A1 (en) | 2004-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |