CA2439902A1 - Drive mechanism for an injection device - Google Patents
Drive mechanism for an injection device Download PDFInfo
- Publication number
- CA2439902A1 CA2439902A1 CA002439902A CA2439902A CA2439902A1 CA 2439902 A1 CA2439902 A1 CA 2439902A1 CA 002439902 A CA002439902 A CA 002439902A CA 2439902 A CA2439902 A CA 2439902A CA 2439902 A1 CA2439902 A1 CA 2439902A1
- Authority
- CA
- Canada
- Prior art keywords
- drive mechanism
- cable
- mechanism according
- injection device
- piston
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31513—Piston constructions to improve sealing or sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/31518—Piston or piston-rod constructions, e.g. connection of piston with piston-rod designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31563—Mechanically operated dose setting member interacting with a displaceable stop member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
Abstract
Injection devices are known for the self administration of medicament by patients. The medicament is typically contained within a cartridge located within the injection device. It is a problem that injection devices should b e small enough to fit into a jacket pocket or a hand bag without difficulty. Also, the injection device must be of a size that enables a piston or simila r used to drive the Cartridge bung within the cartridge to be moved both to a maximum dispense position within the cartridge and to be fully withdrawn fro m the cartridge to allow for replacement of the cartridge. A drive mechanism f or an injection device is disclosed in which the drive mechanism comprises a displaceable dosing spindle 6, a dial dose means 8, a transmission means 10, and a cable means 12, a piston comprising a plurality of nested piston membe rs 30,32,34, displacement of the transmission means 10 causing the cable means 12 to move at least one of one of the nested piston members to drive a cartridg e bung 18.
Claims (4)
1. A drive mechanism for an injection device in which a piston, comprising a plurality of nested piston members, is successively moved in relation to a first end of a medicament cartridge containing a medicament selectively to drive a bung closing a first end of the medicament cartridge into the medicament cartridge to expel medicament through a delivery member located at a second end of the medicament cartridge and further comprising a dial dose means, is characterised in that the drive mechanism yet further comprises a displaceable dosing spindle, a cable means and a transmission means displaceable to cause the cable means to move at least one of the plurality of nested piston members to drive the bung.
2 A drive mechanism according to claim 1, characterised in that the cable is connected at a first end to the transmission means and at a second end to one of the piston members.
3 A drive mechanism according to claim 1 or claim 2, characterised in that the transmission means comprises a spool onto which the cable means is wound, the spool being provided with teeth which engage a threaded portion provided on the displaceable dosing spindle.
4 A drive mechanism according to claim 3 characterised in that the second end of the cable means is connected to an inner piston member and that an intermediate part of the cable means between the first and second ends of the cable means runs over guide means located on other of the nested piston members.
A drive mechanism according to any previous claim, characterised in that return means are provided to return the nested piston members to a retracted position.
6 A drive mechanism according to claim 5, characterised in that return means comprises spring means.
7 A drive mechanism according to claim 1, characterised in that the cable is connected at a first end to an outer piston member and at a second end to an intermediate piston member, the transmission means being adapted to precess along a threaded portion provided on the displaceable dosing spindle..
8~A drive mechanism according to claim 1 or claim 7, characterised in that the transmission means comprises a claw member connected to an inner piston member and that an intermediate part of the cable means between the first and second ends of the cable means runs over a guide means located on the inner piston member.
9 An injection device incorporating a drive mechanism according to any previous claim An injection device according to claim 9,characterised in that the injection device further comprises a displaceable button, displacement of the button causing displacement of the dosing spindle.
A drive mechanism according to any previous claim, characterised in that return means are provided to return the nested piston members to a retracted position.
6 A drive mechanism according to claim 5, characterised in that return means comprises spring means.
7 A drive mechanism according to claim 1, characterised in that the cable is connected at a first end to an outer piston member and at a second end to an intermediate piston member, the transmission means being adapted to precess along a threaded portion provided on the displaceable dosing spindle..
8~A drive mechanism according to claim 1 or claim 7, characterised in that the transmission means comprises a claw member connected to an inner piston member and that an intermediate part of the cable means between the first and second ends of the cable means runs over a guide means located on the inner piston member.
9 An injection device incorporating a drive mechanism according to any previous claim An injection device according to claim 9,characterised in that the injection device further comprises a displaceable button, displacement of the button causing displacement of the dosing spindle.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0107604.1 | 2001-03-27 | ||
GBGB0107604.1A GB0107604D0 (en) | 2001-03-27 | 2001-03-27 | Improvements in and relating to injection device |
PCT/GB2002/001435 WO2002076531A1 (en) | 2001-03-27 | 2002-03-26 | Drive mechanism for an injection device |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2439902A1 true CA2439902A1 (en) | 2002-10-03 |
CA2439902C CA2439902C (en) | 2010-02-23 |
Family
ID=9911629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2439902A Expired - Fee Related CA2439902C (en) | 2001-03-27 | 2002-03-26 | Drive mechanism for an injection device |
Country Status (16)
Country | Link |
---|---|
US (1) | US7008405B2 (en) |
EP (1) | EP1372762B1 (en) |
JP (2) | JP4454228B2 (en) |
KR (1) | KR100854450B1 (en) |
CN (1) | CN1247272C (en) |
AT (1) | ATE354388T1 (en) |
AU (1) | AU2002247843B2 (en) |
BR (1) | BR0208015B1 (en) |
CA (1) | CA2439902C (en) |
DE (1) | DE60218291T2 (en) |
DK (1) | DK1372762T3 (en) |
GB (1) | GB0107604D0 (en) |
HK (1) | HK1061814A1 (en) |
IL (2) | IL157604A0 (en) |
MX (1) | MXPA03008685A (en) |
WO (1) | WO2002076531A1 (en) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6663602B2 (en) | 2000-06-16 | 2003-12-16 | Novo Nordisk A/S | Injection device |
JP3993169B2 (en) | 2002-02-11 | 2007-10-17 | アンタレス・ファーマ・インコーポレーテッド | Intradermal syringe |
ATE551086T1 (en) * | 2004-02-18 | 2012-04-15 | Ares Trading Sa | PORTABLE ELECTRONIC INJECTION DEVICE FOR INJECTING LIQUID MEDICATIONS |
ATE444090T1 (en) | 2004-10-21 | 2009-10-15 | Novo Nordisk As | SELECTION MECHANISM FOR A ROTARY PIN |
CN101132820B (en) | 2005-01-24 | 2010-05-19 | 安塔雷斯制药公司 | Prefilled needle assisted jet injector |
CN101400394B (en) * | 2006-03-10 | 2012-07-04 | 诺沃-诺迪斯克有限公司 | An injection device having a gearing arrangement |
US9144648B2 (en) | 2006-05-03 | 2015-09-29 | Antares Pharma, Inc. | Injector with adjustable dosing |
WO2007131013A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Two-stage reconstituting injector |
JP5253387B2 (en) | 2006-05-18 | 2013-07-31 | ノボ・ノルデイスク・エー/エス | Injection device with mode locking means |
BRPI0817907B8 (en) | 2007-10-02 | 2021-06-22 | Lamodel Ltd | apparatus for administering a substance to an individual |
ES2548447T3 (en) | 2008-03-10 | 2015-10-16 | Antares Pharma, Inc. | Injector safety device |
US8376993B2 (en) | 2008-08-05 | 2013-02-19 | Antares Pharma, Inc. | Multiple dosage injector |
AU2010226442A1 (en) | 2009-03-20 | 2011-10-13 | Antares Pharma, Inc. | Hazardous agent injection system |
CA2757134A1 (en) | 2009-03-31 | 2010-10-07 | Sanofi-Aventis Deutschland Gmbh | Improvements in and relating to medicament delivery devices |
KR101016417B1 (en) * | 2010-04-14 | 2011-02-21 | 김현호 | Agricultural heating equipment using water friction |
US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
US8496619B2 (en) | 2011-07-15 | 2013-07-30 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
US9533106B2 (en) | 2011-12-29 | 2017-01-03 | Novo Nordisk A/S | Torsion-spring based wind-up auto injector pen with dial-up/dial-down mechanism |
EP2822618B1 (en) | 2012-03-06 | 2024-01-10 | Antares Pharma, Inc. | Prefilled syringe with breakaway force feature |
EP2833944A4 (en) | 2012-04-06 | 2016-05-25 | Antares Pharma Inc | Needle assisted jet injection administration of testosterone compositions |
US9364610B2 (en) | 2012-05-07 | 2016-06-14 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
EP2953667B1 (en) | 2013-02-11 | 2019-10-23 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
WO2014164786A1 (en) | 2013-03-11 | 2014-10-09 | Madsen Patrick | Dosage injector with pinion system |
WO2014165136A1 (en) | 2013-03-12 | 2014-10-09 | Antares Pharma, Inc. | Constant volume prefilled syringes and kits thereof |
WO2016091960A1 (en) * | 2014-12-10 | 2016-06-16 | Sanofi | Space saving drug injection device |
US10576207B2 (en) | 2015-10-09 | 2020-03-03 | West Pharma. Services IL, Ltd. | Angled syringe patch injector |
CN112972833B (en) | 2015-10-09 | 2024-01-09 | 西医药服务以色列分公司 | Syringe needle cap remover |
JP6885960B2 (en) | 2016-01-21 | 2021-06-16 | ウェスト ファーマ サービシーズ イスラエル リミテッド | Drug delivery device with visual indicators |
CN109219456B (en) | 2016-01-21 | 2020-05-15 | 西医药服务以色列有限公司 | Force containment in autoinjectors |
CN109310816B (en) | 2016-01-21 | 2020-04-21 | 西医药服务以色列有限公司 | Needle insertion and retraction mechanism |
WO2017161076A1 (en) | 2016-03-16 | 2017-09-21 | Medimop Medical Projects Ltd. | Staged telescopic screw assembly having different visual indicators |
CN109562229B (en) | 2016-08-01 | 2021-07-13 | 西医药服务以色列有限公司 | Anti-rotation medicine barrel pin |
CN110869072B (en) | 2017-05-30 | 2021-12-10 | 西部制药服务有限公司(以色列) | Modular drive mechanism for a wearable injector |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US604297A (en) * | 1898-05-17 | Tilvlepiece | ||
FR2437216A1 (en) * | 1978-09-26 | 1980-04-25 | Arion Henri | Clockwork operated syringe for gradual medication injection - has piston pulled by cable reeling onto winder shaft of alarm clock |
US4659327A (en) * | 1985-11-26 | 1987-04-21 | Dentsply Research & Development Corp. | Multiple dosage syringe |
US5858000A (en) * | 1988-12-14 | 1999-01-12 | Inviro Medical Devices Ltd. | Safety syringe needle device with interchangeable and retractable needle platform |
US5032117A (en) | 1989-01-30 | 1991-07-16 | Motta Louis J | Tandem syringe |
US5271527A (en) * | 1992-04-02 | 1993-12-21 | Habley Medical Technology Corporation | Reusable pharmaceutical dispenser with full stroke indicator |
JP2529819B2 (en) * | 1994-01-27 | 1996-09-04 | 日本イーライリリー株式会社 | Injection device |
DE19717107B4 (en) * | 1997-04-23 | 2005-06-23 | Disetronic Licensing Ag | System of container and drive device for a piston, which is held in the container containing a drug fluid |
US5958896A (en) * | 1997-08-08 | 1999-09-28 | The Mclean Hospital | Cytidine-containing and cytosine-containing compounds as treatments for stimulant exposure |
US5957896A (en) * | 1997-08-11 | 1999-09-28 | Becton, Dickinson And Company | Medication delivery pen |
AU748277B2 (en) * | 1998-01-30 | 2002-05-30 | Novo Nordisk A/S | An injection syringe |
AU2001278417A1 (en) * | 2000-07-14 | 2002-01-30 | Novo-Nordisk A/S | A liquid medication delivery device and a method of delivering an intended dose |
US6508788B2 (en) * | 2000-10-27 | 2003-01-21 | Novo Nordisk A/S | Medication delivery device with telescopic piston rod |
-
2001
- 2001-03-27 GB GBGB0107604.1A patent/GB0107604D0/en not_active Ceased
-
2002
- 2002-03-26 IL IL15760402A patent/IL157604A0/en active IP Right Grant
- 2002-03-26 AU AU2002247843A patent/AU2002247843B2/en not_active Ceased
- 2002-03-26 MX MXPA03008685A patent/MXPA03008685A/en active IP Right Grant
- 2002-03-26 WO PCT/GB2002/001435 patent/WO2002076531A1/en active IP Right Grant
- 2002-03-26 CA CA2439902A patent/CA2439902C/en not_active Expired - Fee Related
- 2002-03-26 CN CNB028070607A patent/CN1247272C/en not_active Expired - Lifetime
- 2002-03-26 JP JP2002575041A patent/JP4454228B2/en not_active Expired - Lifetime
- 2002-03-26 DK DK02716924T patent/DK1372762T3/en active
- 2002-03-26 BR BRPI0208015-0A patent/BR0208015B1/en not_active IP Right Cessation
- 2002-03-26 KR KR1020037012483A patent/KR100854450B1/en not_active IP Right Cessation
- 2002-03-26 EP EP02716924A patent/EP1372762B1/en not_active Expired - Lifetime
- 2002-03-26 US US10/471,717 patent/US7008405B2/en not_active Expired - Lifetime
- 2002-03-26 AT AT02716924T patent/ATE354388T1/en not_active IP Right Cessation
- 2002-03-26 DE DE60218291T patent/DE60218291T2/en not_active Expired - Lifetime
-
2003
- 2003-08-26 IL IL157604A patent/IL157604A/en not_active IP Right Cessation
-
2004
- 2004-07-02 HK HK04104752A patent/HK1061814A1/en not_active IP Right Cessation
-
2009
- 2009-10-23 JP JP2009243933A patent/JP5054750B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE60218291T2 (en) | 2007-10-31 |
CN1498120A (en) | 2004-05-19 |
GB0107604D0 (en) | 2001-05-16 |
CA2439902C (en) | 2010-02-23 |
BR0208015A (en) | 2004-03-02 |
DE60218291D1 (en) | 2007-04-05 |
AU2002247843B2 (en) | 2005-11-24 |
ATE354388T1 (en) | 2007-03-15 |
EP1372762A1 (en) | 2004-01-02 |
MXPA03008685A (en) | 2004-05-17 |
JP2010046507A (en) | 2010-03-04 |
JP2004533285A (en) | 2004-11-04 |
EP1372762B1 (en) | 2007-02-21 |
DK1372762T3 (en) | 2007-06-11 |
IL157604A (en) | 2008-04-13 |
KR100854450B1 (en) | 2008-08-27 |
IL157604A0 (en) | 2004-03-28 |
JP4454228B2 (en) | 2010-04-21 |
US20040092876A1 (en) | 2004-05-13 |
WO2002076531A1 (en) | 2002-10-03 |
CN1247272C (en) | 2006-03-29 |
JP5054750B2 (en) | 2012-10-24 |
BR0208015B1 (en) | 2012-06-12 |
HK1061814A1 (en) | 2004-10-08 |
US7008405B2 (en) | 2006-03-07 |
KR20030093281A (en) | 2003-12-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20170327 |