CA2441493A1 - Convertible fluid feed system with comformable reservoir and methods - Google Patents
Convertible fluid feed system with comformable reservoir and methods Download PDFInfo
- Publication number
- CA2441493A1 CA2441493A1 CA002441493A CA2441493A CA2441493A1 CA 2441493 A1 CA2441493 A1 CA 2441493A1 CA 002441493 A CA002441493 A CA 002441493A CA 2441493 A CA2441493 A CA 2441493A CA 2441493 A1 CA2441493 A1 CA 2441493A1
- Authority
- CA
- Canada
- Prior art keywords
- ampoule
- liquid
- feed system
- region
- aerosol generator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0031—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0638—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
- B05B17/0646—Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S206/00—Special receptacle or package
- Y10S206/828—Medicinal content
Abstract
An aerosolizer feed system (10/12) utilizing an ampoule containing liquid including a housing (28) with an ampoule retaining region (42) and a liquid receiving region (34) adapted to receive liquid dispensed from an ampoule (46).
Claims (49)
1. 1. A feed system for an aerosolizer, the feed system comprising:
a feed system housing having an ampoule region that is adapted to receive an ampoule that contains a liquid and that includes a bottom end and a top end, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule, wherein the liquid receiving region includes an overflow region that extends along side the ampoule region above the bottom end of the ampoule; and an interface that is adapted to couple the liquid receiving region to an aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.
a feed system housing having an ampoule region that is adapted to receive an ampoule that contains a liquid and that includes a bottom end and a top end, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule, wherein the liquid receiving region includes an overflow region that extends along side the ampoule region above the bottom end of the ampoule; and an interface that is adapted to couple the liquid receiving region to an aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.
2. A feed system as in claim 1, wherein the liquid receiving region includes a tapered bottom end with a drain opening to funnel liquid from the ampoule to the aerosol generator.
3. A feed system as in claim 2, wherein the interface is adapted to produce a seal between the bottom end of the liquid receiving region and the aerosol generator.
4. A feed system as in claim 2, wherein the feed system housing includes a top portion and a bottom portion having the tapered bottom end, wherein the top portion is attachable to the bottom portion, and wherein the ampoule region and the overflow region comprise two elongate channels extending through the top portion.
5. A feed system as in claim 4, further comprising an o-ring seal positioned between the top portion and the bottom portion.
6. A feed system as in claim 1, further comprising a lid coupled to the feed system housing that is adapted to secure the ampoule within the ampoule region.
7. A feed system as in claim 6, wherein the lid includes a slot that is adapted to receive a top tab that extends from the top end of the ampoule.
8. A feed system for an aerosolizer, the feed system comprising:
an ampoule containing a liquid, wherein the ampoule has a top end and a bottom end;
a housing having an ampoule region into which the ampoule is held, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule;
an interface that is adapted to couple the liquid receiving region to an aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.
an ampoule containing a liquid, wherein the ampoule has a top end and a bottom end;
a housing having an ampoule region into which the ampoule is held, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule;
an interface that is adapted to couple the liquid receiving region to an aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.
9. A feed system as in claim 8, wherein the liquid receiving region includes an overflow region that extends along side the ampoule region above the bottom end of the ampoule.
10. A feed system as in claim 8, wherein the liquid receiving region includes a tapered bottom end with a drain opening to funnel liquid from the ampoule to the aerosol generator.
11. A feed system as in claim 10, wherein the interface is adapted to produce a seal between the bottom end of the liquid receiving region and the aerosol generator.
12. A feed system as in claim 10, wherein the feed system housing includes a top portion and a bottom portion having the tapered bottom end, wherein the top portion is attachable to the bottom portion, and wherein the ampoule region and the overflow region comprise two elongate channels extending through the top portion.
13. A feed system as in claim 12, further comprising an o-ring seal positioned between the top portion and the bottom portion.
14. A feed system as in claim 8, further comprising a lid coupled to the housing to secure the ampoule within the ampoule region.
15. A feed system as in claim 14, wherein the ampoule includes a top tab extending from the top end, and wherein the lid includes a slot through which the top tab extends.
16. A feed system as in claim 15, wherein the top tab is removable to form a vent opening in the top end of the ampoule.
17. A feed system as in claim 8, wherein the ampoule includes a bottom tab extending from the bottom end, and wherein the bottom tab is removable to form a drain opening in the bottom end of the ampoule.
18. A feed system as in claim 12, wherein the ampoule includes a bottom tab extending from the bottom end, and wherein the bottom tab extends distally beyond the top portion of the housing, and wherein the bottom tab is removable prior to connection of top portion with bottom portion to form a drain opening in the ampoule.
19. An aerosolization device, comprising:
a device housing having an interior and an exit opening;
an aerosol generator disposed within the device housing to eject an aerosolized liquid through the exit opening;
a liquid feed system disposed within the device housing, the liquid feed system comprising a feed system housing having an ampoule region that is adapted to receive an ampoule that contains a liquid, a liquid receiving region that is adapted to receive liquid dispensed from the ampoule, and an interface that couples the liquid receiving region to the aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.
a device housing having an interior and an exit opening;
an aerosol generator disposed within the device housing to eject an aerosolized liquid through the exit opening;
a liquid feed system disposed within the device housing, the liquid feed system comprising a feed system housing having an ampoule region that is adapted to receive an ampoule that contains a liquid, a liquid receiving region that is adapted to receive liquid dispensed from the ampoule, and an interface that couples the liquid receiving region to the aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.
20. A device as in claim 19, wherein the liquid receiving region includes an overflow region that extends along side the ampoule region above the bottom end of the ampoule.
21. A device as in claim 19, wherein the liquid receiving region includes a tapered bottom end with a drain opening to funnel liquid from the ampoule to the aerosol generator.
22. A device as in claim 21, wherein the interface includes a seal member to produce a seal between the bottom end of the liquid receiving region and the aerosol generator.
23. A device as in claim 19, wherein the aerosol generator includes a seal member to produce a seal between the aerosol generator and the interface.~
24. A device as in claim 21, wherein the feed system housing includes a top portion and a bottom portion having the tapered bottom end, wherein the top portion is attachable to the bottom portion to permit the top portion to be removed from the device housing, and wherein the ampoule region and the overflow region comprise two elongate channels extending through the top portion.
25. A device as in claim 24, further comprising an o-ring seal positioned between the top portion and the bottom portion.
26. A device as in claim 19, further comprising a lid coupled to the feed system housing that is adapted to secure the ampoule within the ampoule region.
27. A device as in claim 26, wherein the lid includes a slot that is adapted to receive a top tab that extends from the top end of the ampoule.
28. A device as in claim 19, wherein the aerosol generator comprises a vibratable member having a plurality of apertures and a vibratable element to vibrate the vibratable member.
29. An aerosolization system in kit form, comprising:
an aerosolization device comprising a device housing having an exit opening, an aerosol generator held within the housing to provide an aerosolized liquid through the exit opening, and a liquid receiving portion of a liquid feed system; and a liquid feed system receiver unit having an ampoule containing a liquid to be aerosolized, wherein the receiver unit is insertable into the aerosolization device to couple with the liquid receiving portion.
an aerosolization device comprising a device housing having an exit opening, an aerosol generator held within the housing to provide an aerosolized liquid through the exit opening, and a liquid receiving portion of a liquid feed system; and a liquid feed system receiver unit having an ampoule containing a liquid to be aerosolized, wherein the receiver unit is insertable into the aerosolization device to couple with the liquid receiving portion.
30. A kit as in claim 29, wherein the receiver unit includes an ampoule region having the ampoule and a liquid overflow region adjacent to the ampoule region for receiving overflow liquid from the liquid receiving portion.
31. A kit as in claim 29, wherein the ampoule has a top end and a bottom end, a top tab extending from the top end that is removable to form a vent opening, and a bottom tab extending from the bottom end that is removable to form a drain opening.
32. A kit as in claim 31, wherein the receiver unit has a bottom end with an opening that is sized to permit the bottom tab to extend through the bottom end of the receiver unit.
33. A kit as in claim 31, wherein the receiver unit has a top end with an opening that is sized to permit the top tab to extend through the top end of the receiver unit.
34. A kit as in claim 29, further comprising an o-ring seal positioned between the receiver unit and the liquid receiving portion.
35. A kit as in claim 29, wherein the liquid receiving portion has a tapered bottom end that is operably coupled to the aerosol generator.
36. A kit as in claim 29, wherein the aerosol generator comprises a vibratable member having a plurality of apertures and a vibratable element to vibrate the vibratable member.
37. A method for aerosolizing a liquid, the method comprising:
inserting an ampoule containing a liquid into an aerosolization device having a liquid feed system, an aerosol generator, and an exit opening;
opening the ampoule to permit liquid from the ampoule to drain into a liquid receiving region of the feed system; and operating the aerosol generator to eject liquid droplets through the exit opening.
inserting an ampoule containing a liquid into an aerosolization device having a liquid feed system, an aerosol generator, and an exit opening;
opening the ampoule to permit liquid from the ampoule to drain into a liquid receiving region of the feed system; and operating the aerosol generator to eject liquid droplets through the exit opening.
38. A method as in claim 37, further comprising removing a bottom tab from the ampoule to form drain opening before inserting the ampoule into the aerosolization device.
39. A method as in claim 37, wherein the ampoule is held within a receiver unit of the liquid feed system, and further comprising inserting the receiver unit into the aerosolization device and coupling the receiver unit with the liquid receiving region.
40. A method as in claim 39, further comprising removing the receiver unit from the aerosolization device following operation of the aerosol generator and discarding the receiver unit.
41. A method as in claim 40, further comprising cleaning the aerosol generator following removal of the receiver unit.
42. A method as in claim 37, further comprising removing a top tab from the ampoule to form a vent opening after inserting the ampoule into the aerosolization device.
43. A method as in claim 37, wherein the feed system includes an overflow region adjacent to the ampoule and further comprising permitting excess liquid to flow into the overflow region.
44. A method as in claim 37, further comprising vibrating an aperture plate of the aerosol generator to produce the liquid droplets.
45. A method for aerosolizing a liquid, the method comprising:
inserting a receiver unit of a liquid feed system unit into an aerosolization device having an aerosol generator, wherein the receiver unit includes an ampoule containing a liquid, and wherein the receiver unit is inserted until coupled to a liquid receiving region of the feed system that is interfaced with the aerosol generator;
opening the ampoule to permit liquid from the ampoule to drain into the liquid receiving region; and operating the aerosol generator to eject liquid droplets from the aerosolization device.
inserting a receiver unit of a liquid feed system unit into an aerosolization device having an aerosol generator, wherein the receiver unit includes an ampoule containing a liquid, and wherein the receiver unit is inserted until coupled to a liquid receiving region of the feed system that is interfaced with the aerosol generator;
opening the ampoule to permit liquid from the ampoule to drain into the liquid receiving region; and operating the aerosol generator to eject liquid droplets from the aerosolization device.
46. A method as in claim 45, further comprising removing a bottom tab from the ampoule to form drain opening before inserting the receiver unit into the aerosolization device.
47. A method as in claim 45, further comprising removing a top tab from the ampoule to form a vent opening after inserting the receiver unit into the aerosolization device.
48. A method as in claim 45, wherein the receiver unit includes an overflow region adjacent to the ampoule and further comprising permitting excess liquid to flow into the overflow region.
49. A method as in claim 45, further comprising vibrating an aperture plate of the aerosol generator to produce the liquid droplets.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/812,987 US6948491B2 (en) | 2001-03-20 | 2001-03-20 | Convertible fluid feed system with comformable reservoir and methods |
US09/812,987 | 2001-03-20 | ||
PCT/US2002/008379 WO2002074373A1 (en) | 2001-03-20 | 2002-03-19 | Convertible fluid feed system with comformable reservoir and methods |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2441493A1 true CA2441493A1 (en) | 2002-09-26 |
CA2441493C CA2441493C (en) | 2010-07-13 |
Family
ID=25211148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2441493A Expired - Lifetime CA2441493C (en) | 2001-03-20 | 2002-03-19 | Convertible fluid feed system with comformable reservoir and methods |
Country Status (4)
Country | Link |
---|---|
US (2) | US6948491B2 (en) |
EP (1) | EP1370317A4 (en) |
CA (1) | CA2441493C (en) |
WO (1) | WO2002074373A1 (en) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5758637A (en) | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US6235177B1 (en) | 1999-09-09 | 2001-05-22 | Aerogen, Inc. | Method for the construction of an aperture plate for dispensing liquid droplets |
US7100600B2 (en) * | 2001-03-20 | 2006-09-05 | Aerogen, Inc. | Fluid filled ampoules and methods for their use in aerosolizers |
US7600511B2 (en) * | 2001-11-01 | 2009-10-13 | Novartis Pharma Ag | Apparatus and methods for delivery of medicament to a respiratory system |
US8336545B2 (en) | 2000-05-05 | 2012-12-25 | Novartis Pharma Ag | Methods and systems for operating an aerosol generator |
US7971588B2 (en) | 2000-05-05 | 2011-07-05 | Novartis Ag | Methods and systems for operating an aerosol generator |
WO2002074372A2 (en) | 2001-03-15 | 2002-09-26 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nebulizer having cooling chamber |
JP4795637B2 (en) | 2001-09-28 | 2011-10-19 | カーブ テクノロジー,インコーポレイティド | Nose nebulizer |
US7677467B2 (en) | 2002-01-07 | 2010-03-16 | Novartis Pharma Ag | Methods and devices for aerosolizing medicament |
WO2003057291A1 (en) | 2002-01-07 | 2003-07-17 | Aerogen, Inc. | Devices and methods for nebulizing fluids for inhalation |
EP1474196B1 (en) | 2002-01-15 | 2016-08-17 | Novartis AG | Methods and systems for operating an aerosol generator |
US8122881B2 (en) * | 2002-05-09 | 2012-02-28 | Kurve Technology, Inc. | Particle dispersion device for nasal delivery |
US6915962B2 (en) | 2002-05-20 | 2005-07-12 | Aerogen, Inc. | Apparatus for providing aerosol for medical treatment and methods |
US7718189B2 (en) * | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
US8616195B2 (en) | 2003-07-18 | 2013-12-31 | Novartis Ag | Nebuliser for the production of aerosolized medication |
JP5144070B2 (en) * | 2003-09-05 | 2013-02-13 | カーブ テクノロジー,インコーポレイティド | Integrated nebulizer and particle dispersion chamber for nasal delivery of drugs into the deep nasal cavity and sinuses |
CA2561845C (en) * | 2004-04-02 | 2014-03-25 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Aerosol delivery systems and methods |
US7946291B2 (en) | 2004-04-20 | 2011-05-24 | Novartis Ag | Ventilation systems and methods employing aerosol generators |
FR2875138B1 (en) | 2004-09-15 | 2008-07-11 | Mallinckrodt Dev France Sa | CONTROL METHOD FOR A HEATING HUMIDIFIER |
DE102005006375B4 (en) * | 2005-02-11 | 2007-10-11 | Pari GmbH Spezialisten für effektive Inhalation | Aerosol generating device for inhalation therapy devices |
US9339836B2 (en) * | 2005-05-23 | 2016-05-17 | Biosonic Australia Pty Ltd | Ultrasonic atomization apparatus |
EP1896662B1 (en) * | 2005-05-25 | 2014-07-23 | AeroGen, Inc. | Vibration systems and methods |
DE102005038619A1 (en) * | 2005-08-16 | 2007-02-22 | Pari GmbH Spezialisten für effektive Inhalation | An inhalation therapy device with an ampoule for storing a medicament to be nebulised |
MX2008002560A (en) * | 2005-08-23 | 2008-03-14 | Aerogen Inc | Self-sealing t-piece and valved t-piece. |
ES2798263T3 (en) | 2005-12-08 | 2020-12-10 | Insmed Inc | Lipid-based compositions of anti-infectives for treating lung infections |
TWM297751U (en) * | 2006-03-21 | 2006-09-21 | Taidoc Technology Corp | Liquid nebulizer |
EP3354260B1 (en) * | 2006-04-06 | 2020-12-09 | Insmed Incorporated | Methods for coacervation induced liposomal encapsulation and formulations thereof |
EP2106268B1 (en) | 2006-08-30 | 2018-12-12 | Kurve Technology, Inc. | Aerosol generating and delivery device |
US20100196455A1 (en) | 2007-05-04 | 2010-08-05 | Transave, Inc. | Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof |
US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
US9114081B2 (en) * | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
US8291902B2 (en) | 2007-09-18 | 2012-10-23 | Robert Abrams | Enhanced semi-automatic emergency medication dose nebulizer |
US7836885B2 (en) * | 2007-09-18 | 2010-11-23 | Robert Abrams | Semi-automatic emergency medication dose nebulizer |
US20090151716A1 (en) * | 2007-09-18 | 2009-06-18 | Robert Abrams | Semi-automatic emergency medication dose nebulizer |
DE102007056462B4 (en) * | 2007-11-23 | 2011-10-27 | Pari Pharma Gmbh | Disposable ampoule for a device for generating aerosols |
JP5383097B2 (en) * | 2008-01-25 | 2014-01-08 | キヤノン株式会社 | Drug discharge device and control method thereof |
WO2009103063A2 (en) * | 2008-02-15 | 2009-08-20 | Tsi Incorporated | An automated qualitative mask fit tester |
BRPI0909715A2 (en) * | 2008-03-28 | 2015-10-06 | Alandra Medical S A P I De C V | liquid anesthetic cartridges and vaporizer |
US20120091224A1 (en) * | 2009-02-25 | 2012-04-19 | Health & Life Co., Ltd. | Microdroplet Generation Apparatus |
US10842951B2 (en) | 2010-01-12 | 2020-11-24 | Aerami Therapeutics, Inc. | Liquid insulin formulations and methods relating thereto |
US9180261B2 (en) | 2010-01-12 | 2015-11-10 | Dance Biopharm Inc. | Preservative free insulin formulations and systems and methods for aerosolizing |
US20130269684A1 (en) | 2012-04-16 | 2013-10-17 | Dance Pharmaceuticals, Inc. | Methods and systems for supplying aerosolization devices with liquid medicaments |
US9545488B2 (en) | 2010-01-12 | 2017-01-17 | Dance Biopharm Inc. | Preservative-free single dose inhaler systems |
US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
MX2013004864A (en) * | 2010-11-08 | 2013-08-21 | British American Tobacco Co | Liquid droplet spray device. |
EP4331675A2 (en) | 2012-05-21 | 2024-03-06 | Insmed Incorporated | Systems for treating pulmonary infections |
EP2735328A1 (en) * | 2012-11-27 | 2014-05-28 | PARI Pharma GmbH | Fluid reservoir for an aerosol generation device, combination of fluid reservoir and primary fluid package, and aerosol generation device for use with the fluid reservoir |
JP6529438B2 (en) | 2012-11-29 | 2019-06-12 | インスメッド インコーポレイテッド | Stabilized vancomycin formulation |
BR112015026186B1 (en) | 2013-04-16 | 2022-05-10 | Dance Biopharm Inc | Dispenser and method of supplying a metered volume of a liquid drug to an aerosol dispersion device, and method of making a dispenser |
CN105764616A (en) | 2013-09-09 | 2016-07-13 | 奥姆纽斯特有限责任公司 | Atomizing spray apparatus |
WO2015091171A1 (en) * | 2013-12-19 | 2015-06-25 | Koninklijke Philips N.V. | An assembly for use in liquid a droplet apparatus |
KR102447412B1 (en) | 2014-05-15 | 2022-09-23 | 인스메드 인코포레이티드 | Methods for treating pulmonary non-tuberculous mycobacterial infections |
US10307550B2 (en) | 2014-06-09 | 2019-06-04 | Dance Biopharm Inc. | Liquid drug cartridges and associated dispenser |
EP2957349A1 (en) * | 2014-06-20 | 2015-12-23 | PARI Pharma GmbH | Aerosol generator and aerosol delivery device comprising the aerosol generator |
US10857313B2 (en) | 2014-07-01 | 2020-12-08 | Aerami Therapeutics, Inc. | Liquid nebulization systems and methods |
US10471222B2 (en) | 2014-07-01 | 2019-11-12 | Dance Biopharm Inc. | Aerosolization system with flow restrictor and feedback device |
US11273271B2 (en) | 2014-07-01 | 2022-03-15 | Aerami Therapeutics, Inc. | Aerosolization system with flow restrictor and feedback device |
AU2015308748B2 (en) | 2014-08-28 | 2019-11-07 | Norton (Waterford) Limited | Compliance monitoring module for a breath-actuated inhaler |
FR3026646B1 (en) * | 2014-10-06 | 2019-11-01 | La Diffusion Technique Francaise | FIXED TAMIS NEBULIZATION DEVICE |
CN107530372A (en) | 2015-02-25 | 2018-01-02 | 当斯生物制药有限公司 | Liquid insulin formulations and relative method |
EP3307364A4 (en) * | 2015-06-16 | 2019-06-05 | Cashman, Kathryn | Inhalant device |
DE102017100012A1 (en) | 2017-01-02 | 2018-07-05 | Nebu-Tec Med. Produkte Eike Kern Gmbh | Nebulizer unit with directly connectable ampoule |
WO2019191627A1 (en) | 2018-03-30 | 2019-10-03 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
EP4252804A1 (en) * | 2022-03-28 | 2023-10-04 | Lainomedical S.L. | Nebulizer device |
Family Cites Families (234)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US550315A (en) * | 1895-11-26 | Frank napoleon allen | ||
US2735427A (en) | 1956-02-21 | Hypodermic syringe | ||
US809159A (en) | 1905-09-30 | 1906-01-02 | Richard M Willis | Dispensing bottle or jar. |
US1680616A (en) * | 1922-06-06 | 1928-08-14 | Horst Friedrich Wilhelm | Sealed package |
US2022520A (en) | 1934-07-07 | 1935-11-26 | Parsons Ammonia Company Inc | Bottle |
US2101304A (en) | 1936-06-05 | 1937-12-07 | Sheaffer W A Pen Co | Fountain pen |
US2187528A (en) | 1937-06-07 | 1940-01-16 | Russell T Wing | Fountain pen |
US2158615A (en) | 1937-07-26 | 1939-05-16 | Sheaffer W A Pen Co | Fountain pen |
US2266706A (en) | 1938-08-06 | 1941-12-16 | Stanley L Fox | Nasal atomizing inhaler and dropper |
NL62585C (en) | 1939-01-06 | |||
US2292381A (en) | 1940-12-24 | 1942-08-11 | Esterbrook Steel Pen Mfg Co | Fountain pen feed |
US2283333A (en) | 1941-05-22 | 1942-05-19 | Sheaffer W A Pen Co | Fountain pen |
US2383098A (en) | 1942-07-21 | 1945-08-21 | Jr Frank H Wheaton | Double-mouthed bottle |
US2375770A (en) | 1943-11-19 | 1945-05-15 | Arthur O Dahiberg | Fountain pen |
US2430023A (en) | 1944-01-27 | 1947-11-04 | Esterbrook Pen Co | Writing implement |
BE461043A (en) | 1944-04-10 | |||
US2404063A (en) | 1944-04-27 | 1946-07-16 | Parker Pen Co | Fountain pen |
US2521657A (en) | 1944-07-07 | 1950-09-05 | Scripto Inc | Fountain pen |
US2512004A (en) | 1945-03-05 | 1950-06-20 | Russell T Wing | Fountain pen |
US2474996A (en) | 1945-10-12 | 1949-07-05 | Sheaffer W A Pen Co | Fountain pen |
NL68028C (en) | 1946-06-08 | |||
US2705007A (en) | 1951-09-10 | 1955-03-29 | Louis P Gerber | Inhaler |
US2764979A (en) | 1953-04-09 | 1956-10-02 | Henderson Edward | Medicament dispensing unit |
US2779623A (en) | 1954-09-10 | 1957-01-29 | Bernard J Eisenkraft | Electromechanical atomizer |
US2935970A (en) | 1955-03-23 | 1960-05-10 | Sapphire Products Inc | Fountain pen ink reservoir |
US3103310A (en) | 1961-11-09 | 1963-09-10 | Exxon Research Engineering Co | Sonic atomizer for liquids |
FR1449600A (en) * | 1964-09-14 | 1966-05-06 | Fr Des Laboratoires Labaz Soc | Improvements to flexible material bottles, especially for medicinal products |
US3680954A (en) | 1965-04-30 | 1972-08-01 | Eastman Kodak Co | Electrography |
DE1461628A1 (en) | 1965-04-30 | 1969-03-27 | Montblanc Simplo Gmbh | Ink feed for fountain pen |
US3412854A (en) | 1966-03-21 | 1968-11-26 | Kimberly Clark Co | Apparatus for separation of magnetizable material from stock suspensions |
US3550864A (en) | 1967-12-11 | 1970-12-29 | Borg Warner | High efficiency flashing nozzle |
US3561444A (en) | 1968-05-22 | 1971-02-09 | Bio Logics Inc | Ultrasonic drug nebulizer |
US3515348A (en) | 1968-07-22 | 1970-06-02 | Lewbill Ind Inc | Mist-producing device |
DE1728597C3 (en) * | 1968-08-24 | 1978-09-21 | Sabco Ltd., Albert Park (Australien) | Feed device on a device for applying cleaning foam |
US3558052A (en) | 1968-10-31 | 1971-01-26 | F I N D Inc | Method and apparatus for spraying electrostatic dry powder |
US3563415A (en) | 1969-06-04 | 1971-02-16 | Multi Drop Adapter Corp | Multidrop adapter |
US3719328A (en) | 1970-10-22 | 1973-03-06 | C Hindman | Adjustable spray head |
US3738574A (en) | 1971-06-15 | 1973-06-12 | Siemens Ag | Apparatus for atomizing fluids with a piezoelectrically stimulated oscillator system |
US3838686A (en) | 1971-10-14 | 1974-10-01 | G Szekely | Aerosol apparatus for inhalation therapy |
US3983740A (en) | 1971-12-07 | 1976-10-05 | Societe Grenobloise D'etudes Et D'applications Hydrauliques (Sogreah) | Method and apparatus for forming a stream of identical drops at very high speed |
US3790079A (en) | 1972-06-05 | 1974-02-05 | Rnb Ass Inc | Method and apparatus for generating monodisperse aerosol |
US3778786A (en) | 1972-06-28 | 1973-12-11 | Nasa | Data storage, image tube type |
US3812854A (en) | 1972-10-20 | 1974-05-28 | A Michaels | Ultrasonic nebulizer |
US3842833A (en) | 1972-12-11 | 1974-10-22 | Ims Ltd | Neb-u-pack |
FR2224175B1 (en) | 1973-04-04 | 1978-04-14 | Isf Spa | |
US3804329A (en) | 1973-07-27 | 1974-04-16 | J Martner | Ultrasonic generator and atomizer apparatus and method |
US3903884A (en) | 1973-08-15 | 1975-09-09 | Becton Dickinson Co | Manifold nebulizer system |
DE2361781A1 (en) | 1973-12-12 | 1975-06-19 | Philips Patentverwaltung | WRITING WORK FOR WRITING WITH LIQUID INK |
US3865106A (en) | 1974-03-18 | 1975-02-11 | Bernard P Palush | Positive pressure breathing circuit |
US3951313A (en) | 1974-06-05 | 1976-04-20 | Becton, Dickinson And Company | Reservoir with prepacked diluent |
US3993223A (en) | 1974-07-25 | 1976-11-23 | American Home Products Corporation | Dispensing container |
US3908654A (en) * | 1974-08-02 | 1975-09-30 | Rit Rech Ind Therapeut | Dispensing package for a dry biological and a liquid diluent |
DE2445791C2 (en) | 1974-09-25 | 1984-04-19 | Siemens AG, 1000 Berlin und 8000 München | Ultrasonic liquid atomizer |
AR205589A1 (en) * | 1974-10-09 | 1976-05-14 | Reckitt & Colmann Prod Ltd | INTRODUCING DEVICE OF AN AQUEOUS COMPOSITION INTO A BODY CAVITY |
US3958249A (en) | 1974-12-18 | 1976-05-18 | International Business Machines Corporation | Ink jet drop generator |
US4059384A (en) | 1975-01-20 | 1977-11-22 | Misto2 Gen Equipment Co. | Two-step injection molding |
AT337345B (en) | 1975-02-05 | 1977-06-27 | Draegerwerk Ag | BREATHING ASSISTANCE DEVICE AND / OR ARTIFICIAL VENTILATION DEVICE FOR HUMAN USE |
US4005435A (en) | 1975-05-15 | 1977-01-25 | Burroughs Corporation | Liquid jet droplet generator |
AU67278S (en) | 1975-06-04 | 1975-11-12 | Warner Lambert Co | Bottle |
DE2537765B2 (en) | 1975-08-25 | 1981-04-09 | Siemens AG, 1000 Berlin und 8000 München | Medical inhalation device for the treatment of diseases of the respiratory tract |
GB1571304A (en) | 1976-02-24 | 1980-07-16 | Lucas Industries Ltd | Drive circuit for a piezo electric crystal |
US4094317A (en) | 1976-06-11 | 1978-06-13 | Wasnich Richard D | Nebulization system |
US4121583A (en) | 1976-07-13 | 1978-10-24 | Wen Yuan Chen | Method and apparatus for alleviating asthma attacks |
US4076021A (en) | 1976-07-28 | 1978-02-28 | Thompson Harris A | Positive pressure respiratory apparatus |
US4083368A (en) | 1976-09-01 | 1978-04-11 | Freezer Winthrop J | Inhaler |
USD249958S (en) | 1977-01-10 | 1978-10-17 | Warner-Lambert Company | Dispensing container for pharmaceutical diluents |
US4106503A (en) | 1977-03-11 | 1978-08-15 | Richard R. Rosenthal | Metering system for stimulating bronchial spasm |
US4159803A (en) | 1977-03-31 | 1979-07-03 | MistO2 Gen Equipment Company | Chamber for ultrasonic aerosol generation |
US4113809A (en) | 1977-04-04 | 1978-09-12 | Champion Spark Plug Company | Hand held ultrasonic nebulizer |
US4101041A (en) * | 1977-08-01 | 1978-07-18 | Becton, Dickinson And Company | Prefillable, hermetically sealed container adapted for use with a humidifier or nebulizer head |
US4268460A (en) | 1977-12-12 | 1981-05-19 | Warner-Lambert Company | Nebulizer |
USD259213S (en) | 1978-03-13 | 1981-05-12 | Automatic Liquid Packaging, Inc. | Vial suitable for pharmaceuticals |
DE2811248C3 (en) | 1978-03-15 | 1981-11-26 | Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart | Liquid atomizer |
US4298045A (en) | 1978-04-17 | 1981-11-03 | Automatic Liquid Packaging, Inc. | Dispensing container with plural removable closure means unitary therewith |
US4338576A (en) | 1978-07-26 | 1982-07-06 | Tdk Electronics Co., Ltd. | Ultrasonic atomizer unit utilizing shielded and grounded elements |
US4210155A (en) | 1978-08-03 | 1980-07-01 | Jerry Grimes | Inspirational inhalation spirometer apparatus |
DE2843756B2 (en) | 1978-10-06 | 1981-07-09 | Hense GmbH & Co, 4930 Detmold | Device for generating an aerosol |
US4240081A (en) | 1978-10-13 | 1980-12-16 | Dennison Manufacturing Company | Ink jet printing |
DE2849493C2 (en) | 1978-11-15 | 1982-01-14 | Carl Heyer Gmbh, Inhalationstechnik, 5427 Bad Ems | Hand-held aerosol dispenser |
US4190052A (en) * | 1978-12-18 | 1980-02-26 | The Gillette Company | Steam facial apparatus |
DE2854841C2 (en) | 1978-12-19 | 1981-03-26 | Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart | Liquid atomizer, preferably inhalation device |
JPS5848225B2 (en) | 1979-01-09 | 1983-10-27 | オムロン株式会社 | Atomization amount control method of ultrasonic liquid atomization device |
DE2907348A1 (en) | 1979-02-24 | 1980-09-04 | Boehringer Sohn Ingelheim | IMPROVED INHALATION DEVICES |
US4207990A (en) | 1979-05-03 | 1980-06-17 | Automatic Liquid Packaging, Inc. | Hermetically sealed container with plural access ports |
US4226236A (en) | 1979-05-07 | 1980-10-07 | Abbott Laboratories | Prefilled, vented two-compartment syringe |
US4248227A (en) | 1979-05-14 | 1981-02-03 | Bristol-Myers Company | Fluid unit dispensing device |
US4240417A (en) | 1979-06-13 | 1980-12-23 | Holever Bernard K | Tracheal tube adapter for ventilating apparatus |
DE7917568U1 (en) | 1979-06-19 | 1979-09-20 | Bosch-Siemens Hausgeraete Gmbh, 7000 Stuttgart | INHALATION DEVICE |
JPS5689569A (en) | 1979-12-19 | 1981-07-20 | Canon Inc | Ink jet recording head |
US4368850A (en) | 1980-01-17 | 1983-01-18 | George Szekely | Dry aerosol generator |
DE3010178C2 (en) | 1980-03-17 | 1985-10-03 | Kraftwerk Union AG, 4330 Mülheim | Slotted nozzle equipped with a quick-acting valve to induce pulsed gas flows |
US4336544A (en) | 1980-08-18 | 1982-06-22 | Hewlett-Packard Company | Method and apparatus for drop-on-demand ink jet printing |
JPS5929118B2 (en) | 1980-09-19 | 1984-07-18 | セイコーエプソン株式会社 | Palladium/nickel alloy plating liquid |
US4465234A (en) * | 1980-10-06 | 1984-08-14 | Matsushita Electric Industrial Co., Ltd. | Liquid atomizer including vibrator |
US4474251A (en) | 1980-12-12 | 1984-10-02 | Hydronautics, Incorporated | Enhancing liquid jet erosion |
US4389071A (en) | 1980-12-12 | 1983-06-21 | Hydronautics, Inc. | Enhancing liquid jet erosion |
US4374707A (en) | 1981-03-19 | 1983-02-22 | Xerox Corporation | Orifice plate for ink jet printing machines |
US4454877A (en) | 1981-05-26 | 1984-06-19 | Andrew Boettner | Portable nebulizer or mist producing device |
US4408719A (en) | 1981-06-17 | 1983-10-11 | Last Anthony J | Sonic liquid atomizer |
US4475113A (en) | 1981-06-18 | 1984-10-02 | International Business Machines | Drop-on-demand method and apparatus using converging nozzles and high viscosity fluids |
JPS5861857A (en) | 1981-10-09 | 1983-04-13 | Matsushita Electric Works Ltd | Liquid atomizer |
AU553251B2 (en) | 1981-10-15 | 1986-07-10 | Matsushita Electric Industrial Co., Ltd. | Arrangement for ejecting liquid |
US4474326A (en) | 1981-11-24 | 1984-10-02 | Tdk Electronics Co., Ltd. | Ultrasonic atomizing device |
US4605167A (en) | 1982-01-18 | 1986-08-12 | Matsushita Electric Industrial Company, Limited | Ultrasonic liquid ejecting apparatus |
US5073484A (en) | 1982-03-09 | 1991-12-17 | Bio-Metric Systems, Inc. | Quantitative analysis apparatus and method |
DE3311956A1 (en) | 1982-03-31 | 1983-10-13 | Ricoh Co., Ltd., Tokyo | COLOR JET PRINTER HEAD |
US4566452A (en) * | 1982-07-12 | 1986-01-28 | American Hospital Supply Corporation | Nebulizer |
JPS5912775A (en) | 1982-07-14 | 1984-01-23 | Matsushita Electric Ind Co Ltd | Atomizing pump unit |
US5002582A (en) | 1982-09-29 | 1991-03-26 | Bio-Metric Systems, Inc. | Preparation of polymeric surfaces via covalently attaching polymers |
US4973493A (en) | 1982-09-29 | 1990-11-27 | Bio-Metric Systems, Inc. | Method of improving the biocompatibility of solid surfaces |
US4722906A (en) | 1982-09-29 | 1988-02-02 | Bio-Metric Systems, Inc. | Binding reagents and methods |
IT1156090B (en) | 1982-10-26 | 1987-01-28 | Olivetti & Co Spa | INK JET PRINTING METHOD AND DEVICE |
US4512341A (en) * | 1982-11-22 | 1985-04-23 | Lester Victor E | Nebulizer with capillary feed |
US4632311A (en) | 1982-12-20 | 1986-12-30 | Matsushita Electric Industrial Co., Ltd. | Atomizing apparatus employing a capacitive piezoelectric transducer |
DE3320441A1 (en) | 1983-06-06 | 1984-12-06 | Siemens AG, 1000 Berlin und 8000 München | WRITING DEVICE WORKING WITH LIQUID DROPLETS WITH ROD-SHAPED PIEZOELECTRIC TRANSFORMERS CONNECTED ON BOTH ENDS WITH A NOZZLE PLATE |
US4544933A (en) | 1983-09-20 | 1985-10-01 | Siemens Aktiengesellschaft | Apparatus and method for ink droplet ejection for a printer |
US4593291A (en) | 1984-04-16 | 1986-06-03 | Exxon Research And Engineering Co. | Method for operating an ink jet device to obtain high resolution printing |
DE3574344D1 (en) | 1984-08-29 | 1989-12-28 | Omron Tateisi Electronics Co | Ultrasonic atomizer |
US4628890A (en) | 1984-08-31 | 1986-12-16 | Freeman Winifer W | Fuel atomizer |
DE3582287D1 (en) | 1984-09-07 | 1991-05-02 | Omron Tateisi Electronics Co | VIBRATION GENERATOR FOR AN INHALATION DEVICE WITH ULTRASONIC SPRAYING. |
US4826759A (en) | 1984-10-04 | 1989-05-02 | Bio-Metric Systems, Inc. | Field assay for ligands |
US4550325A (en) | 1984-12-26 | 1985-10-29 | Polaroid Corporation | Drop dispensing device |
DE3500985A1 (en) | 1985-01-14 | 1986-07-17 | Siemens AG, 1000 Berlin und 8000 München | ARRANGEMENT FOR PRODUCING SINGLE DROPLES IN INK WRITING DEVICES |
DE3523947A1 (en) * | 1985-07-04 | 1987-01-08 | Draegerwerk Ag | NARCOSIS EVAPORATOR WITH INTERCHANGEABLE EVAPORATOR CHAMBER |
US4659014A (en) | 1985-09-05 | 1987-04-21 | Delavan Corporation | Ultrasonic spray nozzle and method |
US4702418A (en) | 1985-09-09 | 1987-10-27 | Piezo Electric Products, Inc. | Aerosol dispenser |
US4753579A (en) | 1986-01-22 | 1988-06-28 | Piezo Electric Products, Inc. | Ultrasonic resonant device |
JPS62221352A (en) * | 1986-03-22 | 1987-09-29 | 株式会社新素材総合研究所 | Liquid drug containing container preventing deterioratioan of liquid drug by oxygen and its production |
SE8601351D0 (en) * | 1986-03-24 | 1986-03-24 | Nilsson Sven Erik | MANAGED ADMINISTRATION OF PHYSIOLOGICALLY ACTIVE SUBJECTS |
US4658269A (en) * | 1986-06-02 | 1987-04-14 | Xerox Corporation | Ink jet printer with integral electrohydrodynamic electrodes and nozzle plate |
US4799622A (en) | 1986-08-05 | 1989-01-24 | Tao Nenryo Kogyo Kabushiki Kaisha | Ultrasonic atomizing apparatus |
DE3627222A1 (en) | 1986-08-11 | 1988-02-18 | Siemens Ag | ULTRASONIC POCKET SPRAYER |
US4819834A (en) * | 1986-09-09 | 1989-04-11 | Minnesota Mining And Manufacturing Company | Apparatus and methods for delivering a predetermined amount of a pressurized fluid |
US4979959A (en) | 1986-10-17 | 1990-12-25 | Bio-Metric Systems, Inc. | Biocompatible coating for solid surfaces |
DE3636669C2 (en) * | 1986-10-28 | 2001-08-16 | Siemens Ag | Arrangement for delivering aerosol to a patient's airways and / or lungs |
DE3637631C1 (en) | 1986-11-05 | 1987-08-20 | Philips Patentverwaltung | Process for applying small amounts of molten, drop-shaped solder from a nozzle to surfaces to be wetted and device for carrying out the process |
US4976259A (en) | 1986-12-22 | 1990-12-11 | Mountain Medical Equipment, Inc. | Ultrasonic nebulizer |
EP0282616B1 (en) | 1987-03-17 | 1989-10-04 | Lechler GmbH & Co.KG | Ultrasonic liquid sprayer |
JPS63230957A (en) | 1987-03-20 | 1988-09-27 | Hitachi Ltd | Liquid atomizing device |
US4850534A (en) | 1987-05-30 | 1989-07-25 | Tdk Corporation | Ultrasonic wave nebulizer |
EP0295337B1 (en) | 1987-06-16 | 1991-12-04 | Akzo Nobel N.V. | Two compartment syringe and method of manufacturing |
IL86799A (en) | 1987-07-02 | 1993-03-15 | Kabi Pharmacia Ab | Method and device for injection |
US5080093A (en) * | 1987-07-08 | 1992-01-14 | Vortran Medical Technology, Inc. | Intermittant signal actuated nebulizer |
US5388571A (en) * | 1987-07-17 | 1995-02-14 | Roberts; Josephine A. | Positive-pressure ventilator system with controlled access for nebulizer component servicing |
US4805609A (en) * | 1987-07-17 | 1989-02-21 | Josephine A. Roberts | Pressurized ventilation system for patients |
DE3724629A1 (en) | 1987-07-22 | 1989-02-02 | Siemens Ag | PIEZOELECTRICALLY REQUIRED RESONANCE SYSTEM |
US5139016A (en) | 1987-08-07 | 1992-08-18 | Sorin Biomedica S.P.A. | Process and device for aerosol generation for pulmonary ventilation scintigraphy |
JPH0817804B2 (en) * | 1987-12-23 | 1996-02-28 | 雪印乳業株式会社 | Disinfectant vaporizer |
FI82808C (en) | 1987-12-31 | 1991-04-25 | Etelae Haemeen Keuhkovammayhdi | Ultraljudfinfördelningsanordning |
DE3818682A1 (en) * | 1988-06-01 | 1989-12-21 | Deussen Stella Kg | AMPOULE |
US5201322A (en) * | 1988-08-17 | 1993-04-13 | Elf Atochem North America, Inc. | Device for detecting air flow through a passageway |
US5511726A (en) * | 1988-09-23 | 1996-04-30 | Battelle Memorial Institute | Nebulizer device |
US5021701A (en) | 1988-10-20 | 1991-06-04 | Tdk Corporation | Piezoelectric vibrator mounting system for a nebulizer |
USD312209S (en) | 1988-10-21 | 1990-11-20 | Becton, Dickinson And Company | Dispensing vial or the like |
JPH02269058A (en) | 1989-03-14 | 1990-11-02 | Seiko Epson Corp | Liquid drop jet device by use of rayleigh mode surface acoustic wave |
WO1990012655A1 (en) | 1989-04-14 | 1990-11-01 | Azerbaidzhansky Politekhnichesky Institut Imeni Ch.Ildryma | Device for ultrasonic dispersion of a liquid medium |
US5086785A (en) * | 1989-08-10 | 1992-02-11 | Abrams/Gentille Entertainment Inc. | Angular displacement sensors |
US5007419A (en) * | 1989-09-25 | 1991-04-16 | Allan Weinstein | Inhaler device |
US5152456A (en) * | 1989-12-12 | 1992-10-06 | Bespak, Plc | Dispensing apparatus having a perforate outlet member and a vibrating device |
US5002048A (en) * | 1989-12-12 | 1991-03-26 | Makiej Jr Walter J | Inhalation device utilizing two or more aerosol containers |
DE59001705D1 (en) | 1990-02-07 | 1993-07-15 | Vetter & Co Apotheker | DOUBLE CHAMBER SYRINGE AND METHOD OF USE. |
SG45171A1 (en) * | 1990-03-21 | 1998-01-16 | Boehringer Ingelheim Int | Atomising devices and methods |
US5122116A (en) * | 1990-04-24 | 1992-06-16 | Science Incorporated | Closed drug delivery system |
JPH0411175U (en) * | 1990-05-17 | 1992-01-30 | ||
FR2665849B1 (en) * | 1990-08-20 | 1995-03-24 | Dynamad | ULTRASONIC DEVICE FOR THE CONTINUOUS PRODUCTION OF PARTICLES. |
USD327008S (en) | 1990-08-29 | 1992-06-16 | True Products Sampling, Inc. | Cosmetic sample container |
US5086765A (en) * | 1990-08-29 | 1992-02-11 | Walter Levine | Nebulizer |
US5115803A (en) | 1990-08-31 | 1992-05-26 | Minnesota Mining And Manufacturing Company | Aerosol actuator providing increased respirable fraction |
DE69117127T2 (en) * | 1990-10-11 | 1996-11-07 | Toda Koji | Ultrasonic atomizer |
DE69127826T2 (en) * | 1990-12-17 | 1998-04-09 | Minnesota Mining & Mfg | INHALATION DEVICE |
US5186164A (en) * | 1991-03-15 | 1993-02-16 | Puthalath Raghuprasad | Mist inhaler |
WO1992017231A1 (en) * | 1991-03-28 | 1992-10-15 | Innomed, Inc. | Microelectronic inhaler having a counter and timer |
US5938117A (en) * | 1991-04-24 | 1999-08-17 | Aerogen, Inc. | Methods and apparatus for dispensing liquids as an atomized spray |
US5164740A (en) | 1991-04-24 | 1992-11-17 | Yehuda Ivri | High frequency printing mechanism |
US6540154B1 (en) * | 1991-04-24 | 2003-04-01 | Aerogen, Inc. | Systems and methods for controlling fluid feed to an aerosol generator |
DE69210096T2 (en) * | 1991-05-27 | 1996-09-19 | Tdk Corp | Ultrasonic atomizer |
US5180482A (en) * | 1991-07-22 | 1993-01-19 | At&T Bell Laboratories | Thermal annealing of palladium alloys |
US5601077A (en) * | 1991-08-07 | 1997-02-11 | Becton, Dickinson And Company | Nasal syringe sprayer with removable dose limiting structure |
US5518179A (en) * | 1991-12-04 | 1996-05-21 | The Technology Partnership Limited | Fluid droplets production apparatus and method |
US5186166A (en) * | 1992-03-04 | 1993-02-16 | Riggs John H | Powder nebulizer apparatus and method of nebulization |
US5512474A (en) * | 1992-05-29 | 1996-04-30 | Bsi Corporation | Cell culture support containing a cell adhesion factor and a positively-charged molecule |
US5392769A (en) * | 1992-10-06 | 1995-02-28 | Vinatroics Division | One-way valve |
GB2272389B (en) * | 1992-11-04 | 1996-07-24 | Bespak Plc | Dispensing apparatus |
US5346132A (en) * | 1992-11-12 | 1994-09-13 | Gary S. Hahn | Mist generator |
US5724957A (en) * | 1993-01-29 | 1998-03-10 | Aradigm Corporation | Intrapulmonary delivery of narcotics |
US6012450A (en) * | 1993-01-29 | 2000-01-11 | Aradigm Corporation | Intrapulmonary delivery of hematopoietic drug |
US5279568A (en) * | 1993-04-30 | 1994-01-18 | Spruhventile Gmbh | Pharmaceutical pump dispenser for fluid suspensions and fluid mixtures |
US5303854A (en) * | 1993-03-08 | 1994-04-19 | Spruhventile Gmbh | Pharmaceutical pump dispenser having hydraulically closed outlet port |
US5383906A (en) * | 1993-05-12 | 1995-01-24 | Burchett; Mark T. | Nursing bottle with medication dispenser |
US5396883A (en) * | 1993-05-18 | 1995-03-14 | Knupp; Jacob E. | Nebulizer valve assembly for use in a ventilation circuit |
US5497763A (en) * | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
US5709202A (en) * | 1993-05-21 | 1998-01-20 | Aradigm Corporation | Intrapulmonary delivery of aerosolized formulations |
GB9311892D0 (en) * | 1993-06-09 | 1993-07-28 | Glaxo Wellcome Australia Ltd | Device |
CH686872A5 (en) * | 1993-08-09 | 1996-07-31 | Disetronic Ag | Medical Inhalationsgeraet. |
GB9324250D0 (en) * | 1993-11-25 | 1994-01-12 | Minnesota Mining & Mfg | Inhaler |
US5489266A (en) * | 1994-01-25 | 1996-02-06 | Becton, Dickinson And Company | Syringe assembly and method for lyophilizing and reconstituting injectable medication |
US5479920A (en) * | 1994-03-01 | 1996-01-02 | Vortran Medical Technology, Inc. | Breath actuated medicinal aerosol delivery apparatus |
JP2642056B2 (en) * | 1994-04-22 | 1997-08-20 | 日本冶金工業株式会社 | Ferritic stainless steel for heat exchanger |
AU128844S (en) * | 1994-10-21 | 1996-12-05 | Glaxo Wellcome Australia Ltd | Ampoule |
US5707818A (en) * | 1994-12-13 | 1998-01-13 | Bsi Corporation | Device and method for simultaneously performing multiple competitive immunoassays |
US5582330A (en) * | 1994-12-28 | 1996-12-10 | Allergan, Inc. | Specific volume dispenser |
DE59505300D1 (en) * | 1995-03-09 | 1999-04-15 | Hansen Bernd | Plastic bottle and process for its manufacture |
ZA962078B (en) * | 1995-03-14 | 1996-09-25 | Siemens Ag | Ultrasonic atomizer device with removable precision dosating unit |
US5970974A (en) * | 1995-03-14 | 1999-10-26 | Siemens Aktiengesellschaft | Dosating unit for an ultrasonic atomizer device |
US5586550A (en) * | 1995-08-31 | 1996-12-24 | Fluid Propulsion Technologies, Inc. | Apparatus and methods for the delivery of therapeutic liquids to the respiratory system |
US5758637A (en) * | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US6205999B1 (en) * | 1995-04-05 | 2001-03-27 | Aerogen, Inc. | Methods and apparatus for storing chemical compounds in a portable inhaler |
US6014970A (en) * | 1998-06-11 | 2000-01-18 | Aerogen, Inc. | Methods and apparatus for storing chemical compounds in a portable inhaler |
US6085740A (en) * | 1996-02-21 | 2000-07-11 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
CA2222136C (en) * | 1995-05-26 | 2005-04-05 | Bsi Corporation | Method and implantable article for promoting endothelialization |
US5609798A (en) * | 1995-06-07 | 1997-03-11 | Msp Corporation | High output PSL aerosol generator |
SE9502957D0 (en) * | 1995-08-28 | 1995-08-28 | Pharmacia Ab | Device for displacing a member in a container |
US5639851A (en) * | 1995-10-02 | 1997-06-17 | Ethicon, Inc. | High strength, melt processable, lactide-rich, poly(lactide-CO-P-dioxanone) copolymers |
US5714360A (en) * | 1995-11-03 | 1998-02-03 | Bsi Corporation | Photoactivatable water soluble cross-linking agents containing an onium group |
US6026809A (en) * | 1996-01-25 | 2000-02-22 | Microdose Technologies, Inc. | Inhalation device |
USD392184S (en) * | 1996-02-21 | 1998-03-17 | Automatic Liquid Packaging, Inc. | Vial with a frangible closure |
FR2746656B1 (en) * | 1996-03-26 | 1999-05-28 | System Assistance Medical | PRESSURE SENSOR NEBULIZER |
SE9601719D0 (en) * | 1996-05-06 | 1996-05-06 | Siemens Elema Ab | Dosage for supply of additive gas or liquid to respiratory gas in anesthesia or ventilator |
AUPN976496A0 (en) * | 1996-05-10 | 1996-05-30 | Glaxo Wellcome Australia Ltd | Unit dose dispensing device |
US5778459A (en) * | 1997-02-10 | 1998-07-14 | Guerin; Phillip M. | Method and apparatus for injecting chemicals into the water of a toilet bowl |
US6037587A (en) * | 1997-10-17 | 2000-03-14 | Hewlett-Packard Company | Chemical ionization source for mass spectrometry |
EP1129741B1 (en) * | 1997-11-19 | 2006-04-12 | Microflow Engineering SA | Spray device for an inhaler |
US6358058B1 (en) * | 1998-01-30 | 2002-03-19 | 1263152 Ontario Inc. | Aerosol dispensing inhaler training device |
JP4082787B2 (en) * | 1998-06-16 | 2008-04-30 | 富士フイルム株式会社 | Treatment agent replenisher |
US6182662B1 (en) * | 1998-07-23 | 2001-02-06 | Mcghee Chad J. | Intravenous transport/support device |
US6196218B1 (en) * | 1999-02-24 | 2001-03-06 | Ponwell Enterprises Ltd | Piezo inhaler |
US6530370B1 (en) * | 1999-09-16 | 2003-03-11 | Instrumentation Corp. | Nebulizer apparatus |
MXPA02010884A (en) * | 2000-05-05 | 2003-03-27 | Aerogen Ireland Ltd | Apparatus and methods for the delivery of medicaments to the respiratory system. |
US6341732B1 (en) * | 2000-06-19 | 2002-01-29 | S. C. Johnson & Son, Inc. | Method and apparatus for maintaining control of liquid flow in a vibratory atomizing device |
US6851626B2 (en) * | 2002-01-07 | 2005-02-08 | Aerogen, Inc. | Methods and devices for nebulizing fluids |
WO2003059423A1 (en) * | 2002-01-15 | 2003-07-24 | Aerogen, Inc. | Systems and methods for clearing aerosols from the effective anatomic dead space |
US6860268B2 (en) * | 2002-02-06 | 2005-03-01 | Shelly Bohn | Pediatric ventilation mask and headgear system |
US6915962B2 (en) * | 2002-05-20 | 2005-07-12 | Aerogen, Inc. | Apparatus for providing aerosol for medical treatment and methods |
US8616195B2 (en) * | 2003-07-18 | 2013-12-31 | Novartis Ag | Nebuliser for the production of aerosolized medication |
-
2001
- 2001-03-20 US US09/812,987 patent/US6948491B2/en not_active Expired - Lifetime
-
2002
- 2002-03-19 CA CA2441493A patent/CA2441493C/en not_active Expired - Lifetime
- 2002-03-19 EP EP02728510A patent/EP1370317A4/en not_active Ceased
- 2002-03-19 WO PCT/US2002/008379 patent/WO2002074373A1/en not_active Application Discontinuation
-
2004
- 2004-06-30 US US10/882,888 patent/US7195011B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US20040256488A1 (en) | 2004-12-23 |
US20020134372A1 (en) | 2002-09-26 |
EP1370317A4 (en) | 2006-09-13 |
CA2441493C (en) | 2010-07-13 |
WO2002074373A1 (en) | 2002-09-26 |
US7195011B2 (en) | 2007-03-27 |
EP1370317A1 (en) | 2003-12-17 |
US6948491B2 (en) | 2005-09-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2441493A1 (en) | Convertible fluid feed system with comformable reservoir and methods | |
JP4399617B2 (en) | Ink cartridge simple filling unit | |
US5793389A (en) | Fluid purge apparatus and method for ink jet printer pen | |
MY135751A (en) | Method and apparatus for dispensing liquids in aerosolized form with minimum spillage | |
CA2212903A1 (en) | Washing device for automatic biochemical analyzer | |
EP1149602A3 (en) | Spray device for an inhaler suitable for respiratory therapies | |
CA2561486A1 (en) | Liquid dispensing apparatus and methods | |
WO2002102295A3 (en) | Spike for liquid transfer device, liquid transfer device including spike, and method of transferring liquids using the same | |
JP2004508183A5 (en) | ||
EP1598193A3 (en) | Ink jet recording apparatus | |
ATE39107T1 (en) | DEVICE FOR WATER PURIFICATION. | |
JP4055818B2 (en) | Cleaning device for hair removal equipment | |
EP1201152A3 (en) | Beauty appliance | |
CA2368267A1 (en) | Mop wringer | |
EP0805034A3 (en) | Ink barrier for Fluid reservoir vacuum or pressure line | |
JPS58108153A (en) | Ink cartridge | |
WO2002100501A3 (en) | De-sludging device and method for de-sludging a liquid | |
ATE304395T1 (en) | RINSING DEVICE FOR REMOVAL OF RESIDUE | |
CN110876549B (en) | Cup body assembly and food processor | |
JP3127295B1 (en) | Beverage container cleaning equipment | |
DE69934197D1 (en) | Device for liquid removal from an inkjet printer | |
JP3816207B2 (en) | Liquid pouring tool | |
JP2584663Y2 (en) | Coffee extractor | |
FR2791280B1 (en) | DEVICE FOR EJECTING LIQUID DROPS | |
ES296257U (en) | Method for extracting fumes. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20220321 |