CA2449059A1 - Polymer controlled induced viscosity fiber system and uses thereof - Google Patents
Polymer controlled induced viscosity fiber system and uses thereof Download PDFInfo
- Publication number
- CA2449059A1 CA2449059A1 CA002449059A CA2449059A CA2449059A1 CA 2449059 A1 CA2449059 A1 CA 2449059A1 CA 002449059 A CA002449059 A CA 002449059A CA 2449059 A CA2449059 A CA 2449059A CA 2449059 A1 CA2449059 A1 CA 2449059A1
- Authority
- CA
- Canada
- Prior art keywords
- induced viscosity
- meal replacement
- viscosity
- human
- fiber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000835 fiber Substances 0.000 title claims abstract 28
- 229920000642 polymer Polymers 0.000 title claims 12
- 238000000034 method Methods 0.000 claims abstract 19
- 229920002472 Starch Polymers 0.000 claims abstract 8
- 235000019698 starch Nutrition 0.000 claims abstract 7
- 239000008107 starch Substances 0.000 claims abstract 7
- 235000019525 fullness Nutrition 0.000 claims abstract 2
- 230000002641 glycemic effect Effects 0.000 claims abstract 2
- 230000001939 inductive effect Effects 0.000 claims abstract 2
- 230000000291 postprandial effect Effects 0.000 claims abstract 2
- 235000019627 satiety Nutrition 0.000 claims abstract 2
- 230000036186 satiety Effects 0.000 claims abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 7
- 235000021486 meal replacement product Nutrition 0.000 claims 7
- 235000012054 meals Nutrition 0.000 claims 7
- 150000001720 carbohydrates Chemical class 0.000 claims 6
- 235000014633 carbohydrates Nutrition 0.000 claims 6
- 238000001727 in vivo Methods 0.000 claims 4
- 230000007935 neutral effect Effects 0.000 claims 4
- 235000016709 nutrition Nutrition 0.000 claims 4
- 102000004139 alpha-Amylases Human genes 0.000 claims 3
- 108090000637 alpha-Amylases Proteins 0.000 claims 3
- 229940024171 alpha-amylase Drugs 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 229920002907 Guar gum Polymers 0.000 claims 2
- 239000000665 guar gum Substances 0.000 claims 2
- 235000010417 guar gum Nutrition 0.000 claims 2
- 229960002154 guar gum Drugs 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 claims 1
- 244000247812 Amorphophallus rivieri Species 0.000 claims 1
- 235000001206 Amorphophallus rivieri Nutrition 0.000 claims 1
- 235000016068 Berberis vulgaris Nutrition 0.000 claims 1
- 241000335053 Beta vulgaris Species 0.000 claims 1
- 229920002261 Corn starch Polymers 0.000 claims 1
- 229920001503 Glucan Polymers 0.000 claims 1
- 229920002581 Glucomannan Polymers 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 229920002752 Konjac Polymers 0.000 claims 1
- 229920000161 Locust bean gum Polymers 0.000 claims 1
- 229920002774 Maltodextrin Polymers 0.000 claims 1
- 239000005913 Maltodextrin Substances 0.000 claims 1
- 240000003183 Manihot esculenta Species 0.000 claims 1
- 235000016735 Manihot esculenta subsp esculenta Nutrition 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008120 corn starch Substances 0.000 claims 1
- 235000013312 flour Nutrition 0.000 claims 1
- 229940046240 glucomannan Drugs 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 239000000252 konjac Substances 0.000 claims 1
- 235000010485 konjac Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000000711 locust bean gum Substances 0.000 claims 1
- 235000010420 locust bean gum Nutrition 0.000 claims 1
- 229940035034 maltodextrin Drugs 0.000 claims 1
- 229920000609 methyl cellulose Polymers 0.000 claims 1
- 239000001923 methylcellulose Substances 0.000 claims 1
- 235000010981 methylcellulose Nutrition 0.000 claims 1
- 230000035764 nutrition Effects 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 229920001592 potato starch Polymers 0.000 claims 1
- 229940100486 rice starch Drugs 0.000 claims 1
- 230000004580 weight loss Effects 0.000 claims 1
- 229940100445 wheat starch Drugs 0.000 claims 1
- 239000012263 liquid product Substances 0.000 abstract 2
Classifications
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention relates generally to a method of blunting the postprandial glycemic response in a human by feeding an induced viscosity fiber system together with lightly hydrolyzed starch. The invention also relates to an induced viscosity fiber system and the liquid products that incorporate the induced viscosity fiber system. Further, the invention relat es to a method of incorporating soluble fiber into a liquid product without the typical negative organoleptic or physical stability issues. The invention al so relates to a method of inducing the feeling of fullness and satiety by feedi ng the induced viscosity fiber system.
Claims (28)
1. A polymer controlled induced viscosity fiber system comprising:
a. a satiating amount of neutral soluble fiber source and b. sufficient quantity of lightly hydrolyzed starch.
a. a satiating amount of neutral soluble fiber source and b. sufficient quantity of lightly hydrolyzed starch.
2. The induced viscosity system according to claim 1 wherein said neutral soluble fiber source is selected from the group consisting of guar gum, pectin, locust bean gum, methylcellulose, .beta.-glucans, glucomannan, and konjac flour and mixtures thereof.
3. The induced viscosity system according to claim 1 wherein said lightly hydrolyzed starch is selected from the group consisting of corn starch, potato starch, beet starch, tapioca starch, rice starch, wheat starch and mixtures thereof.
4. The induced viscosity system according to claim 3 wherein the DP of said lightly hydrolyzed starch is at least about 10.
5. The induced viscosity system according to claim 1 which generates an in vivo viscosity of at least 300 cps when exposed to alpha-amylase.
6. The induced viscosity system according to claim 1 wherein said neutral soluble fiber and lightly hydrolyzed starch are in a ratio of from about 0.35:5 to 1:5.
7. A method for blunting the postprandial glycemic response of a diabetic patient comprising administering to said diabetic patient a sufficient quantity of the polymer controlled induced viscosity fiber system according to claim 1.
8. The method according to claim 7 in which said polymer controlled induced viscosity fiber system is contained in a meal replacement product.
9. The method according to claim 8 in which said polymer controlled induced viscosity fiber system comprises at least 10w/w% of the total carbohydrate contained within said product, when determined on a dry weight basis.
10. The method according to claim 8 in which said meal replacement product comprises:
a) a protein system providing from about 10 to about 35% of total calories b) a fat system providing less than about 37% of total calories, and;
c) a carbohydrate system providing from about 25 to about 75% of total calories.
a) a protein system providing from about 10 to about 35% of total calories b) a fat system providing less than about 37% of total calories, and;
c) a carbohydrate system providing from about 25 to about 75% of total calories.
11. The method according to claim 10 in which the polymer controlled induced viscosity fiber system makes up at least 10 w/w% of the total carbohydrate of said product.
12. The method according to claim 11 wherein said meal replacement product generates an in vivo viscosity of at least 300 cps when exposed to alpha amylase.
13. A method for providing nutrition to a diabetic patient comprising feeding to said diabetic patient the polymer controlled induced viscosity fiber system according to claim 1.
14. A method of incorporating soluble fiber into a low viscosity ready-to-feed liquid nutritional comprising adding the polymer controlled induced viscosity fiber system according to claim 1 to said nutritional.
15. The method according to claim 14 wherein the viscosity of said ready-to-feed nutritional is less than 300 cps.
16. A method of inducing viscosity in vivo comprising feeding to an individual the polymer controlled induced viscosity fiber system according to claim 1.
17. A meal replacement product comprising:
b. a protein system;
c. a fat system, and;
d. a carbohydrate system which includes the polymer controlled induced viscosity fiber system according to claim 1.
b. a protein system;
c. a fat system, and;
d. a carbohydrate system which includes the polymer controlled induced viscosity fiber system according to claim 1.
18. The meal replacement product according to claim 17 in which said product contains:
a. a protein system providing from about 10 to about 35% of total calories b. a fat system providing less than about 37% of total calories, and;
c. a carbohydrate system providing from about 25 to about 75% of total calories, in which at least 10w/w% of said carbohydrate system is a polymer controlled induced viscosity fiber system, said fiber system comprises neutral soluble fiber and lightly hydrolyzed starch in a ratio of from about 0.35:5 to 1:5.
a. a protein system providing from about 10 to about 35% of total calories b. a fat system providing less than about 37% of total calories, and;
c. a carbohydrate system providing from about 25 to about 75% of total calories, in which at least 10w/w% of said carbohydrate system is a polymer controlled induced viscosity fiber system, said fiber system comprises neutral soluble fiber and lightly hydrolyzed starch in a ratio of from about 0.35:5 to 1:5.
19. A method of delivering soluble fiber to diabetic patients comprising feeding the meal replacement according to claim 18.
20. A method for assisting a diabetic patient with managing their blood glucose levels comprising feeding said patient the meal replacement according to claim 18.
21. A method for producing satiety in a human comprising feeding said human the meal replacement according to claim 18.
22. A method for assisting a human to lose weight comprising feeding said human the meal replacement according to claim 18.
23. A method for promoting weight loss in a human comprising feeding to said human the meal replacement according to claim 18.
24. A method of promoting the feeling of fullness in a human comprising feeding to said human the meal replacement according to claim 18.
25. A method of delivering a soluble fiber to a person in need of losing weight comprising feeding to said human the meal replacement according to claim 18.
26. An article of manufacture comprising a packaged meal replacement product, in which said product contains the induced viscosity fiber system according to claim 1 and said article bears a label indicating the contents should be consumed by a diabetic.
27. An article of manufacture comprising a packaged meal replacement product, in which said product contains the induced viscosity fiber system according to claim 1 and said article bears a label indicating the contents should be consumed by a human attempting to lose weight.
28. A polymer controlled induced viscosity fiber system comprising guar gum and DP100 maltodextrin in a ratio of from 1 to 5, wherein said fiber system generates an in vivo viscosity of greater than 300 cps when exposed to alpha amylase.
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CA2449053A Expired - Fee Related CA2449053C (en) | 2001-05-31 | 2002-05-29 | Dual viscosity fiber system and uses thereof |
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