CA2464670A1 - Transdermal transport device with suction - Google Patents
Transdermal transport device with suction Download PDFInfo
- Publication number
- CA2464670A1 CA2464670A1 CA002464670A CA2464670A CA2464670A1 CA 2464670 A1 CA2464670 A1 CA 2464670A1 CA 002464670 A CA002464670 A CA 002464670A CA 2464670 A CA2464670 A CA 2464670A CA 2464670 A1 CA2464670 A1 CA 2464670A1
- Authority
- CA
- Canada
- Prior art keywords
- needle
- transport device
- needles
- suction
- transdermal transport
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M2005/1401—Functional features
- A61M2005/1405—Patient controlled analgesia [PCA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
- A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1581—Right-angle needle-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0266—Shape memory materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/65—Impedance, e.g. conductivity, capacity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
- A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
Abstract
A transdermal transport device includes a reservoir for holding a formulatio n of an active principle, and one or more needles (14). Each needle has a bore through which the formulation is transported between the reservoir and a biological body, and has an end portion that is substantially algined in a plane parallel to a surfaceof the biological body when the device is placed on the surface. The device also includes a vaccum generator (28) which creates a suction to draw a portion of the surface beyond the plane of the end portion s to enable the end portions to penetrate the portion of the surface as the needles are translated along an axis that is substantially parallel to the plane.
Claims (10)
1. A transdermal transport device, comprising:
a reservoir for holding a formulation of an active principle;
one or more needles, each needle having a bore through which the formulation is transported between the reservoir and a biological body, each needle having an end portion that is substantially aligned in a plane parallel to a surface of the biological body when the device is placed on the surface;
and a vacuum generator which creates a suction to draw a portion of the surface beyond the of the end portions to enable the end portions to penetrate the portion of the surface as the needles are translated along an axis that is substantially parallel to the plane.
a reservoir for holding a formulation of an active principle;
one or more needles, each needle having a bore through which the formulation is transported between the reservoir and a biological body, each needle having an end portion that is substantially aligned in a plane parallel to a surface of the biological body when the device is placed on the surface;
and a vacuum generator which creates a suction to draw a portion of the surface beyond the of the end portions to enable the end portions to penetrate the portion of the surface as the needles are translated along an axis that is substantially parallel to the plane.
2. The transdermal transport device of claim 1 wherein the vacuum is used to secure the device to the surface of the body.
3. The transdermal transport device of claim 2 wherein the vacuum is turned off after the needles penetrate the skin.
4. The transdermal transport device of claim 1 wherein the needles are rotated about an axis that is substantially perpendicular to the plane.
5. The transdermal transport device of claim 1 further comprising a mechanical stop to limit the depth of needle penetration.
6. A transdermal transport device, comprising:
a means for holding a formulation of an active principle;
a needle to transport the formulation between the means for holding the liquid formulation and a target area of a biological body;
a means for creating a suction to draw a portion of the target area towards the needle to facilitate penetrating the portion of the target area with the needle; and a mechanical stop to limit the depth of needle penetration.
a means for holding a formulation of an active principle;
a needle to transport the formulation between the means for holding the liquid formulation and a target area of a biological body;
a means for creating a suction to draw a portion of the target area towards the needle to facilitate penetrating the portion of the target area with the needle; and a mechanical stop to limit the depth of needle penetration.
7. A method of transdermally transporting a formulation of an active principle, comprising:
generating a suction to draw a portion of a target area of a biological body towards an array of needles of a transdermal transport device, each needle have an end portion which is substantially aligned in a plane parallel to a surface of the biological body; and driving the end portions into the portion of the target area.
generating a suction to draw a portion of a target area of a biological body towards an array of needles of a transdermal transport device, each needle have an end portion which is substantially aligned in a plane parallel to a surface of the biological body; and driving the end portions into the portion of the target area.
8. The method of claim 7, wherein the suction secures the device to the surface of the body.
9. The method of claim 8, further comprising turning off the suction after the end portions have penetrated the portion of the target area.
10. The method of claim 7, wherein driving includes rotating the end portions of the needles about an axis that is substantially perpendicular to the plane that is parallel to the surface of the biological body.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33842501P | 2001-10-26 | 2001-10-26 | |
US60/338,425 | 2001-10-26 | ||
US39948902P | 2002-07-29 | 2002-07-29 | |
US60/399,489 | 2002-07-29 | ||
PCT/US2002/033830 WO2003037407A1 (en) | 2001-10-26 | 2002-10-22 | Transdermal transport device with suction |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2464670A1 true CA2464670A1 (en) | 2003-05-08 |
CA2464670C CA2464670C (en) | 2011-04-26 |
Family
ID=26991185
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2464483A Expired - Fee Related CA2464483C (en) | 2001-10-26 | 2002-10-18 | Microneedle transport device |
CA2464485A Expired - Fee Related CA2464485C (en) | 2001-10-26 | 2002-10-21 | Microneedle transdermal transport device |
CA2464673A Expired - Fee Related CA2464673C (en) | 2001-10-26 | 2002-10-22 | Impedance sensor |
CA002464487A Abandoned CA2464487A1 (en) | 2001-10-26 | 2002-10-22 | Transdermal transport device with an electrolytic actuator |
CA2464670A Expired - Fee Related CA2464670C (en) | 2001-10-26 | 2002-10-22 | Transdermal transport device with suction |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2464483A Expired - Fee Related CA2464483C (en) | 2001-10-26 | 2002-10-18 | Microneedle transport device |
CA2464485A Expired - Fee Related CA2464485C (en) | 2001-10-26 | 2002-10-21 | Microneedle transdermal transport device |
CA2464673A Expired - Fee Related CA2464673C (en) | 2001-10-26 | 2002-10-22 | Impedance sensor |
CA002464487A Abandoned CA2464487A1 (en) | 2001-10-26 | 2002-10-22 | Transdermal transport device with an electrolytic actuator |
Country Status (8)
Country | Link |
---|---|
US (7) | US7429258B2 (en) |
EP (5) | EP1439871B1 (en) |
JP (10) | JP2005525141A (en) |
AT (3) | ATE420680T1 (en) |
AU (3) | AU2002353840B2 (en) |
CA (5) | CA2464483C (en) |
DE (3) | DE60230896D1 (en) |
WO (5) | WO2003037403A1 (en) |
Families Citing this family (391)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6464628B1 (en) | 1999-08-12 | 2002-10-15 | Obtech Medical Ag | Mechanical anal incontinence |
US6471635B1 (en) | 2000-02-10 | 2002-10-29 | Obtech Medical Ag | Anal incontinence disease treatment with controlled wireless energy supply |
US6461292B1 (en) | 1999-08-12 | 2002-10-08 | Obtech Medical Ag | Anal incontinence treatment with wireless energy supply |
US6482145B1 (en) | 2000-02-14 | 2002-11-19 | Obtech Medical Ag | Hydraulic anal incontinence treatment |
DE60110747T2 (en) | 2000-02-10 | 2006-02-23 | Potencia Medical Ag | MECHANICAL DEVICE FOR IMPOTENCE TREATMENT |
MXPA02007649A (en) | 2000-02-10 | 2004-08-23 | Potencia Medical Ag | Urinary incontinence treatment with wireless energy supply. |
DE60113377T2 (en) | 2000-02-10 | 2006-06-14 | Potencia Medical Ag | CONTROLLED HARNINE INCONTINENCE TREATMENT |
ATE380006T1 (en) | 2000-02-11 | 2007-12-15 | Potencia Medical Ag | CONTROLLED IMPOTENCY TREATMENT |
US20030125768A1 (en) | 2000-02-11 | 2003-07-03 | Forsell Peter | Impotence treatment apparatus with energy transforming means |
DE60111019T2 (en) | 2000-02-14 | 2006-05-11 | Potencia Medical Ag | PROSTHESIS |
CA2397284C (en) | 2000-02-14 | 2010-05-18 | Potencia Medical Ag | Male impotence prosthesis apparatus with wireless energy supply |
US20030100929A1 (en) | 2000-02-14 | 2003-05-29 | Peter Forsell | Controlled penile prosthesis |
US7419481B2 (en) * | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
EP1227094B1 (en) * | 2001-01-30 | 2005-12-14 | Nissan Chemical Industries Ltd. | Isocyanurate compound and method for producing the same |
US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US7025774B2 (en) * | 2001-06-12 | 2006-04-11 | Pelikan Technologies, Inc. | Tissue penetration device |
US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
US6966880B2 (en) * | 2001-10-16 | 2005-11-22 | Agilent Technologies, Inc. | Universal diagnostic platform |
US7429258B2 (en) | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
US6908453B2 (en) * | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
US7858112B2 (en) * | 2002-02-28 | 2010-12-28 | Lintec Corporation | Percutaneous absorption system and percutaneous absorption method |
US7115108B2 (en) * | 2002-04-02 | 2006-10-03 | Becton, Dickinson And Company | Method and device for intradermally delivering a substance |
US6912417B1 (en) | 2002-04-05 | 2005-06-28 | Ichor Medical Systmes, Inc. | Method and apparatus for delivery of therapeutic agents |
US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
US8784335B2 (en) * | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
US7226461B2 (en) | 2002-04-19 | 2007-06-05 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with sterility barrier release |
US20040039289A1 (en) * | 2002-04-30 | 2004-02-26 | Christensen Lars Hofmann | Needle insertion sensor |
JP4764626B2 (en) | 2002-05-06 | 2011-09-07 | ベクトン・ディキンソン・アンド・カンパニー | Method and device for controlling the pharmacokinetics of a drug |
EP1389476A1 (en) * | 2002-08-14 | 2004-02-18 | Precimedix S.A. | Programming device for a pump for injecting medicaments |
JP2005537054A (en) * | 2002-08-30 | 2005-12-08 | ベクトン・ディキンソン・アンド・カンパニー | Methods for controlling the pharmacokinetics of immunomodulatory compounds |
US20120296233A9 (en) * | 2002-09-05 | 2012-11-22 | Freeman Dominique M | Methods and apparatus for an analyte detecting device |
US7530975B2 (en) | 2002-09-06 | 2009-05-12 | Massachusetts Institute Of Technology | Measuring properties of an anatomical body |
US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
CN100346746C (en) * | 2003-03-06 | 2007-11-07 | 生命扫描有限公司 | System and method for piercing dermal tissue |
WO2006001797A1 (en) * | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
WO2004112723A2 (en) | 2003-06-20 | 2004-12-29 | Ronald Aung-Din | Tropical therapy for the treatment of migraines, muscle sprains, muscle spasm, spasticity and related conditions |
CA2534823A1 (en) * | 2003-08-04 | 2005-02-24 | Alza Corporation | Method and device for enhancing transdermal agent flux |
EP1671096A4 (en) | 2003-09-29 | 2009-09-16 | Pelikan Technologies Inc | Method and apparatus for an improved sample capture device |
EP1680014A4 (en) | 2003-10-14 | 2009-01-21 | Pelikan Technologies Inc | Method and apparatus for a variable user interface |
EP1527792A1 (en) | 2003-10-27 | 2005-05-04 | Novo Nordisk A/S | Medical injection device mountable to the skin |
US20070191815A1 (en) | 2004-09-13 | 2007-08-16 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
AU2004287414B2 (en) * | 2003-10-31 | 2010-11-25 | Alza Corporation | Self-actuating applicator for microprojection array |
US7361182B2 (en) | 2003-12-19 | 2008-04-22 | Lightnix, Inc. | Medical lancet |
WO2005063115A1 (en) * | 2003-12-22 | 2005-07-14 | Hadvary Paul | Dermallly affixed sensor device |
AU2004311977A1 (en) * | 2003-12-29 | 2005-07-21 | 3M Innovative Properties Company | Medical devices and kits including same |
EP1706026B1 (en) | 2003-12-31 | 2017-03-01 | Sanofi-Aventis Deutschland GmbH | Method and apparatus for improving fluidic flow and sample capture |
JP5221127B2 (en) * | 2004-03-08 | 2013-06-26 | アイコアー メディカル システムズ、インク. | An improved device for the transfer of therapeutic agents using electricity |
JP4981660B2 (en) * | 2004-04-12 | 2012-07-25 | アラーガン、インコーポレイテッド | Multi-site injection system |
WO2005118060A2 (en) * | 2004-04-30 | 2005-12-15 | Boston Scientific Limited | Apparatus with partially insulated needle for measuring tissue impedance and method using same |
US8828203B2 (en) | 2004-05-20 | 2014-09-09 | Sanofi-Aventis Deutschland Gmbh | Printable hydrogels for biosensors |
EP1765194A4 (en) * | 2004-06-03 | 2010-09-29 | Pelikan Technologies Inc | Method and apparatus for a fluid sampling device |
US9775553B2 (en) * | 2004-06-03 | 2017-10-03 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US8247946B2 (en) | 2004-06-14 | 2012-08-21 | Massachusetts Institute Of Technology | Electrochemical actuator |
WO2005124918A2 (en) | 2004-06-14 | 2005-12-29 | Massachusetts Institute Of Technology | Electrochemical actuating methods, devices and structures |
US7872396B2 (en) * | 2004-06-14 | 2011-01-18 | Massachusetts Institute Of Technology | Electrochemical actuator |
US7837733B2 (en) | 2004-06-29 | 2010-11-23 | Spine Wave, Inc. | Percutaneous methods for injecting a curable biomaterial into an intervertebral space |
US20060030811A1 (en) * | 2004-08-03 | 2006-02-09 | Wong Patrick S | Method and device for enhancing transdermal agent flux |
WO2006016364A2 (en) * | 2004-08-10 | 2006-02-16 | Hellman De Picciotto, Tania | Drug delivery devices |
JP5082053B2 (en) | 2004-08-16 | 2012-11-28 | イノチュア アイ・ピー リミテッド | Manufacturing method of microneedle or microimplant |
US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
CA2587386C (en) | 2004-11-18 | 2013-01-15 | 3M Innovative Properties Company | Microneedle array applicator and retainer |
KR20130026511A (en) * | 2004-11-18 | 2013-03-13 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | Low-profile microneedle array applicator |
US8057842B2 (en) | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
WO2006055844A2 (en) | 2004-11-18 | 2006-05-26 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
JP4927751B2 (en) * | 2004-11-18 | 2012-05-09 | スリーエム イノベイティブ プロパティズ カンパニー | Microneedle array coating method |
US20080009800A1 (en) * | 2004-12-02 | 2008-01-10 | Nickel Janice H | Transdermal drug delivery device |
CN100367906C (en) * | 2004-12-08 | 2008-02-13 | 圣美迪诺医疗科技(湖州)有限公司 | Endermic implantating biological sensors |
US7850645B2 (en) | 2005-02-11 | 2010-12-14 | Boston Scientific Scimed, Inc. | Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power |
US7833189B2 (en) | 2005-02-11 | 2010-11-16 | Massachusetts Institute Of Technology | Controlled needle-free transport |
EP1709989A1 (en) * | 2005-04-04 | 2006-10-11 | Christoph Burckhardt AG | Tattoo machine |
EP1709906A1 (en) * | 2005-04-07 | 2006-10-11 | F. Hoffmann-La Roche Ag | Method and device for blood sampling |
WO2006108185A1 (en) * | 2005-04-07 | 2006-10-12 | 3M Innovative Properties Company | System and method for tool feedback sensing |
EP1877116A1 (en) | 2005-04-13 | 2008-01-16 | Novo Nordisk A/S | Medical skin mountable device and system |
ES2527340T3 (en) * | 2005-05-24 | 2015-01-22 | Chrono Therapeutics, Inc. | Portable drug delivery device that includes a removable and replaceable dosage or administration element |
US8372040B2 (en) | 2005-05-24 | 2013-02-12 | Chrono Therapeutics, Inc. | Portable drug delivery device including a detachable and replaceable administration or dosing element |
US20080269666A1 (en) * | 2005-05-25 | 2008-10-30 | Georgia Tech Research Corporation | Microneedles and Methods for Microinfusion |
JP5148274B2 (en) * | 2005-05-27 | 2013-02-20 | オリンパス株式会社 | Intra-subject introduction device |
US8505544B2 (en) * | 2005-05-31 | 2013-08-13 | The Board Of Trustees Of The Leland Stanford Junior University | Optically-implemented microsurgery system and approach |
EP1893256B1 (en) * | 2005-06-16 | 2012-09-26 | Novo Nordisk A/S | Method and apparatus for assisting patients in self administration of medication |
US20080195035A1 (en) * | 2005-06-24 | 2008-08-14 | Frederickson Franklyn L | Collapsible Patch and Method of Application |
CA2613111C (en) * | 2005-06-27 | 2015-05-26 | 3M Innovative Properties Company | Microneedle array applicator device and method of array application |
US9162037B2 (en) | 2005-07-06 | 2015-10-20 | Vascular Pathways, Inc. | Intravenous catheter insertion device and method of use |
IL175460A (en) | 2006-05-07 | 2011-05-31 | Doron Aurbach | Drug delivery device |
US9687186B2 (en) | 2005-07-21 | 2017-06-27 | Steadymed Ltd. | Drug delivery device |
US8518069B2 (en) | 2005-09-07 | 2013-08-27 | Cabochon Aesthetics, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US10548659B2 (en) | 2006-01-17 | 2020-02-04 | Ulthera, Inc. | High pressure pre-burst for improved fluid delivery |
US9486274B2 (en) | 2005-09-07 | 2016-11-08 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9011473B2 (en) | 2005-09-07 | 2015-04-21 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9358033B2 (en) | 2005-09-07 | 2016-06-07 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
US20070066934A1 (en) * | 2005-09-19 | 2007-03-22 | Transport Pharmaceuticals, Inc. | Electrokinetic delivery system and methods therefor |
US20070185432A1 (en) * | 2005-09-19 | 2007-08-09 | Transport Pharmaceuticals, Inc. | Electrokinetic system and method for delivering methotrexate |
US8545445B2 (en) * | 2006-02-09 | 2013-10-01 | Deka Products Limited Partnership | Patch-sized fluid delivery systems and methods |
JP4935286B2 (en) * | 2005-10-12 | 2012-05-23 | パナソニック株式会社 | Blood sensor |
JP2009511223A (en) | 2005-10-17 | 2009-03-19 | ノボ・ノルデイスク・エー/エス | Vented drug reservoir unit |
SI2926847T1 (en) * | 2005-11-02 | 2022-10-28 | Medicaltree Patents Ltd. | Implantable infusion device with advanceable and retractable needle |
US9248317B2 (en) | 2005-12-02 | 2016-02-02 | Ulthera, Inc. | Devices and methods for selectively lysing cells |
US7885793B2 (en) | 2007-05-22 | 2011-02-08 | International Business Machines Corporation | Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution |
US9636035B2 (en) * | 2005-12-14 | 2017-05-02 | Scibase Ab | Medical apparatus for determination of biological conditions using impedance measurements |
JP4402648B2 (en) * | 2005-12-16 | 2010-01-20 | オリンパス株式会社 | Intra-subject introduction device |
US7736310B2 (en) | 2006-01-30 | 2010-06-15 | Abbott Diabetes Care Inc. | On-body medical device securement |
EP1815790A1 (en) * | 2006-02-04 | 2007-08-08 | Roche Diagnostics GmbH | Lancet device with impedance measuring unit |
US11318249B2 (en) | 2006-02-09 | 2022-05-03 | Deka Products Limited Partnership | Infusion pump assembly |
ATE532553T1 (en) | 2006-02-10 | 2011-11-15 | Hisamitsu Pharmaceutical Co | TRANSDERMAL DRUG ADMINISTRATION DEVICE WITH MICRONEEDLES |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
US7981034B2 (en) | 2006-02-28 | 2011-07-19 | Abbott Diabetes Care Inc. | Smart messages and alerts for an infusion delivery and management system |
DE602007012417D1 (en) | 2006-03-14 | 2011-03-24 | Univ Southern California | Mems device for drug release |
WO2007124411A1 (en) * | 2006-04-20 | 2007-11-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
US7918814B2 (en) * | 2006-05-02 | 2011-04-05 | Georgia Tech Research Corporation | Method for drug delivery to ocular tissue using microneedle |
US7621895B2 (en) * | 2006-05-17 | 2009-11-24 | Abbott Cardiovascular Systems Inc. | Needle array devices and methods |
US20070276318A1 (en) * | 2006-05-26 | 2007-11-29 | Mit, Llp | Iontosonic-microneedle applicator apparatus and methods |
US20090171269A1 (en) * | 2006-06-29 | 2009-07-02 | Abbott Diabetes Care, Inc. | Infusion Device and Methods Therefor |
US9119582B2 (en) | 2006-06-30 | 2015-09-01 | Abbott Diabetes Care, Inc. | Integrated analyte sensor and infusion device and methods therefor |
US20090326441A1 (en) * | 2006-08-01 | 2009-12-31 | Agency For Science ,Technology And Research | Ultrasonic Enhanced Microneedles |
US8932216B2 (en) | 2006-08-07 | 2015-01-13 | Abbott Diabetes Care Inc. | Method and system for providing data management in integrated analyte monitoring and infusion system |
US8206296B2 (en) | 2006-08-07 | 2012-06-26 | Abbott Diabetes Care Inc. | Method and system for providing integrated analyte monitoring and infusion system therapy management |
JP2010502267A (en) * | 2006-08-28 | 2010-01-28 | エージェンシー・フォー・サイエンス・テクノロジー・アンド・リサーチ | Microneedle and method for producing microneedle |
CA2661912A1 (en) * | 2006-08-29 | 2008-03-06 | Alza Corporation | Drug electrotransport with hydration measurement of hydratable reservoir |
US20090318833A1 (en) * | 2006-09-18 | 2009-12-24 | Agency For Science Technology And Research | Needle Structures and Methods for Fabricating Needle Structures |
CA2664972C (en) | 2006-10-05 | 2016-07-26 | Technion Research & Development Foundation Ltd. | Microtubes and methods of producing same |
EP2084802B1 (en) | 2006-10-25 | 2019-03-06 | Roche Diabetes Care GmbH | Uninterruptible power supply for a medical appliance |
EP2076172A4 (en) * | 2006-10-27 | 2012-03-21 | Aretais Inc | Use of coherent raman techniques for medical diagnostic and therapeutic purposes, and calibration techniques for same |
US10525246B2 (en) * | 2006-12-22 | 2020-01-07 | Nanomed Skincare, Inc. | Microdevice and method for transdermal delivery and sampling of active substances |
US8845530B2 (en) * | 2007-01-02 | 2014-09-30 | Isense Corporation | Resposable biosensor assembly and method of sensing |
FR2912919B1 (en) * | 2007-02-22 | 2009-05-01 | Bernard Perriere | MINIATURIZED INJECTION DEVICE FOR MEDICAL USE |
US20080249469A1 (en) * | 2007-03-22 | 2008-10-09 | Ponnambalam Selvaganapathy | Method and apparatus for active control of drug delivery using electro-osmotic flow control |
ES2817249T3 (en) | 2007-04-16 | 2021-04-06 | Corium Inc | Microneedle matrices obtained by dissolution and casting containing an active principle |
GB2448493B (en) * | 2007-04-16 | 2009-10-14 | Dewan Fazlul Hoque Chowdhury | Microneedle transdermal delivery device |
JP5139518B2 (en) | 2007-05-07 | 2013-02-06 | バスキュラー・パスウェイズ・インコーポレイテッド | Venous catheter insertion device |
US20090069830A1 (en) * | 2007-06-07 | 2009-03-12 | Piezo Resonance Innovations, Inc. | Eye surgical tool |
DK2158908T3 (en) * | 2007-06-21 | 2013-07-29 | Fujimoto Co Ltd | Composition for transdermal administration |
US8641618B2 (en) | 2007-06-27 | 2014-02-04 | Abbott Diabetes Care Inc. | Method and structure for securing a monitoring device element |
US8085151B2 (en) | 2007-06-28 | 2011-12-27 | Abbott Diabetes Care Inc. | Signal converting cradle for medical condition monitoring and management system |
US10219832B2 (en) | 2007-06-29 | 2019-03-05 | Actuated Medical, Inc. | Device and method for less forceful tissue puncture |
US8160900B2 (en) | 2007-06-29 | 2012-04-17 | Abbott Diabetes Care Inc. | Analyte monitoring and management device and method to analyze the frequency of user interaction with the device |
US8043229B2 (en) * | 2007-06-29 | 2011-10-25 | Actuated Medical, Inc. | Medical tool for reduced penetration force |
US8328738B2 (en) * | 2007-06-29 | 2012-12-11 | Actuated Medical, Inc. | Medical tool for reduced penetration force with feedback means |
US9987468B2 (en) | 2007-06-29 | 2018-06-05 | Actuated Medical, Inc. | Reduced force device for intravascular access and guidewire placement |
US7828771B2 (en) * | 2007-07-26 | 2010-11-09 | Entra Pharmaceuticals, Inc. | Systems and methods for delivering drugs |
CN101801445B (en) * | 2007-08-14 | 2013-04-17 | 弗雷德哈钦森癌症研究中心 | Needle array assembly for delivering therapeutic agents |
WO2009029044A1 (en) * | 2007-08-24 | 2009-03-05 | Agency For Science, Technology And Research | A system and method for detecting skin penetration |
WO2009029572A1 (en) * | 2007-08-24 | 2009-03-05 | Deka Products Limited Partnership | Microneedle systems and apparatus |
US9096845B2 (en) * | 2007-08-29 | 2015-08-04 | Technion Research & Development Foundation Limited | Encapsulation of bacteria and viruses in electrospun fibers |
US20090088682A1 (en) * | 2007-09-28 | 2009-04-02 | Seattle Medical Technologies | Wearable infusion device |
US8439940B2 (en) | 2010-12-22 | 2013-05-14 | Cabochon Aesthetics, Inc. | Dissection handpiece with aspiration means for reducing the appearance of cellulite |
JP5461427B2 (en) * | 2007-12-17 | 2014-04-02 | ニューワールド ファーマシューティカルズ,エルエルシー | Integrated intradermal delivery, diagnosis and communication system |
EP2666510B1 (en) | 2007-12-20 | 2017-10-18 | University Of Southern California | Apparatus for controlled delivery of therapeutic agents |
FI20075978A0 (en) * | 2007-12-31 | 2007-12-31 | Katja Paassilta | Arrangement and method |
CN114796703A (en) | 2007-12-31 | 2022-07-29 | 德卡产品有限公司 | Infusion pump assembly |
US8414563B2 (en) | 2007-12-31 | 2013-04-09 | Deka Products Limited Partnership | Pump assembly with switch |
US11357910B2 (en) | 2007-12-31 | 2022-06-14 | Deka Products Limited Partnership | Pump assembly with switch |
US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
WO2009096855A1 (en) * | 2008-01-28 | 2009-08-06 | Milux Holding Sa | Blood clot removal device, system, and method |
EP2240140B8 (en) | 2008-01-29 | 2022-05-18 | Implantica Patent Ltd. | An apparatus for treating gerd |
US9464368B2 (en) * | 2008-02-21 | 2016-10-11 | Technion Research & Development Foundation Ltd. | Methods of attaching a molecule-of-interest to a microtube |
WO2009108836A1 (en) * | 2008-02-29 | 2009-09-03 | Path Scientific, Llc | Unitized painfree blood glucose measuring device |
JP2009222474A (en) * | 2008-03-14 | 2009-10-01 | Panasonic Corp | Micro-liquid transfer apparatus and micro-mliquid transfer method |
US9849238B2 (en) | 2008-05-08 | 2017-12-26 | Minipumps, Llc | Drug-delivery pump with intelligent control |
US8486278B2 (en) | 2008-05-08 | 2013-07-16 | Minipumps, Llc | Drug-delivery pumps and methods of manufacture |
CN102202719B (en) | 2008-05-08 | 2014-11-26 | 迷你泵有限责任公司 | Implantable pums and cannulas therefor |
CN102105108B (en) | 2008-05-21 | 2013-12-04 | 谢拉杰克特股份有限公司 | Method of manufacturing solid solution peforator patches and uses thereof |
US8591410B2 (en) | 2008-05-30 | 2013-11-26 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
US8924159B2 (en) | 2008-05-30 | 2014-12-30 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
AU2009269129B2 (en) | 2008-06-30 | 2015-08-20 | Afgin Pharma, Llc | Topical regional neuro-affective therapy |
CN101960144A (en) * | 2008-07-08 | 2011-01-26 | 松下电器产业株式会社 | Fluid conveying device using electrically conductive polymer |
US8868176B2 (en) * | 2008-07-22 | 2014-10-21 | New York University | Microelectrode-equipped subdural therapeutic agent delivery strip |
EP2626093B1 (en) * | 2008-08-28 | 2014-02-12 | Medingo Ltd. | Device for enhanced subcutaneous insulin absorption |
US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
AU2009293019A1 (en) | 2008-09-19 | 2010-03-25 | Tandem Diabetes Care Inc. | Solute concentration measurement device and related methods |
US8509894B2 (en) | 2008-10-10 | 2013-08-13 | Milux Holding Sa | Heart help device, system, and method |
EP2346548B1 (en) | 2008-10-10 | 2021-06-16 | MedicalTree Patent Ltd. | Heart help device, and system |
WO2010042046A1 (en) | 2008-10-10 | 2010-04-15 | Milux Holding S.A. | Apparatus, system and operation method for the treatment of female sexual dysfunction |
EP2349096B1 (en) | 2008-10-10 | 2021-01-27 | MedicalTree Patent Ltd. | An improved artificial valve |
US11123171B2 (en) | 2008-10-10 | 2021-09-21 | Peter Forsell | Fastening means for implantable medical control assembly |
US8874215B2 (en) | 2008-10-10 | 2014-10-28 | Peter Forsell | System, an apparatus, and a method for treating a sexual dysfunctional female patient |
US9168364B2 (en) | 2008-11-04 | 2015-10-27 | Janisys Limited | Transfer device for transferring a substance between the device and a subject |
US20110301628A1 (en) * | 2008-12-05 | 2011-12-08 | Yossi Gross | Techniques for use with a nail penetration device |
EP2370141A1 (en) | 2008-12-19 | 2011-10-05 | Janisys Limited | A fluid transfer device and an active substance cartridge for the fluid transfer device, and a method for controlling the pressure at which an active substance is delivered to a subject from a fluid transfer device |
US20100187132A1 (en) * | 2008-12-29 | 2010-07-29 | Don Alden | Determination of the real electrochemical surface areas of screen printed electrodes |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
US9041541B2 (en) | 2010-01-28 | 2015-05-26 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
US9033898B2 (en) | 2010-06-23 | 2015-05-19 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
CN102405015B (en) | 2009-03-02 | 2017-01-18 | 第七感生物系统有限公司 | Devices and methods for the analysis of an extractable medium |
US20110105951A1 (en) * | 2009-10-30 | 2011-05-05 | Seventh Sense Biosystems, Inc. | Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin |
US20110172508A1 (en) * | 2010-01-13 | 2011-07-14 | Seventh Sense Biosystems, Inc. | Sampling device interfaces |
US20110172510A1 (en) * | 2010-01-13 | 2011-07-14 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or withdrawal of fluids |
US9295417B2 (en) | 2011-04-29 | 2016-03-29 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
WO2012018486A2 (en) | 2010-07-26 | 2012-02-09 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or receiving of fluids |
JP5563652B2 (en) | 2009-03-17 | 2014-07-30 | カーディオスライヴ インコーポレイテッド | External defibrillator |
US8781576B2 (en) * | 2009-03-17 | 2014-07-15 | Cardiothrive, Inc. | Device and method for reducing patient transthoracic impedance for the purpose of delivering a therapeutic current |
DE102009002019A1 (en) * | 2009-03-31 | 2010-10-07 | Robert Bosch Gmbh | Applicator for the treatment of skin |
WO2010125551A2 (en) * | 2009-04-29 | 2010-11-04 | Janisys Limited | A micro-needle device and apparatus and a method for applying a micro-needle element to a site on the skin of a subject |
US8483967B2 (en) | 2009-04-29 | 2013-07-09 | Abbott Diabetes Care Inc. | Method and system for providing real time analyte sensor calibration with retrospective backfill |
JP2012527272A (en) * | 2009-05-20 | 2012-11-08 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Drug delivery device |
US9949812B2 (en) | 2009-07-17 | 2018-04-24 | Peter Forsell | Vaginal operation method for the treatment of anal incontinence in women |
US10952836B2 (en) | 2009-07-17 | 2021-03-23 | Peter Forsell | Vaginal operation method for the treatment of urinary incontinence in women |
EP3284494A1 (en) | 2009-07-30 | 2018-02-21 | Tandem Diabetes Care, Inc. | Portable infusion pump system |
US10010706B2 (en) | 2009-07-31 | 2018-07-03 | 3M Innovative Properties Company | Hollow microneedle arrays |
US11096708B2 (en) | 2009-08-07 | 2021-08-24 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
US9358064B2 (en) | 2009-08-07 | 2016-06-07 | Ulthera, Inc. | Handpiece and methods for performing subcutaneous surgery |
JP5758388B2 (en) | 2009-08-18 | 2015-08-05 | ミニパンプス, エルエルシー | Electrolyte drug delivery pump with adaptive control |
US8758271B2 (en) | 2009-09-01 | 2014-06-24 | Massachusetts Institute Of Technology | Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties |
US20110060202A1 (en) * | 2009-09-08 | 2011-03-10 | Seth Adrian Miller | Dehydration detector using micro-needles |
DK2475408T3 (en) * | 2009-09-10 | 2015-05-26 | Sanofi Aventis Deutschland | Drug container |
US8834423B2 (en) | 2009-10-23 | 2014-09-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | Dissolvable microneedle arrays for transdermal delivery to human skin |
US8685038B2 (en) | 2009-12-07 | 2014-04-01 | Incube Labs, Llc | Iontophoretic apparatus and method for marking of the skin |
WO2011084511A1 (en) | 2009-12-15 | 2011-07-14 | Massachusetts Institute Of Technology | Jet injector use in oral evaluation |
US20110172637A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Drug delivery device including tissue support structure |
EP3243435A1 (en) * | 2010-01-13 | 2017-11-15 | Seventh Sense Biosystems, Inc. | Sampling device interfaces |
US8366667B2 (en) * | 2010-02-11 | 2013-02-05 | Baxter International Inc. | Flow pulsatility dampening devices |
US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
CN103108665A (en) | 2010-04-20 | 2013-05-15 | 迷你泵有限责任公司 | Electrolytically driven drug pump devices |
JP5868953B2 (en) | 2010-04-28 | 2016-02-24 | キンバリー クラーク ワールドワイド インコーポレイテッド | Injection mold microneedle array and manufacturing method thereof |
MX345837B (en) | 2010-04-28 | 2017-02-16 | Kimberly-Clark Worldwide Incorporated | Device for delivery of rheumatoid arthritis medication. |
WO2011135531A2 (en) | 2010-04-28 | 2011-11-03 | Kimberly-Clark Worldwide, Inc. | MEDICAL DEVICES FOR DELIVERY OF siRNA |
US9629979B2 (en) * | 2010-04-28 | 2017-04-25 | Sanovas, Inc. | Pressure/Vacuum actuated catheter drug delivery probe |
CA2796965C (en) | 2010-04-28 | 2019-04-16 | Kimberly-Clark Worldwide, Inc. | Method for increasing permeability of an epithelial barrier |
ES2719595T3 (en) | 2010-05-04 | 2019-07-11 | Corium Int Inc | Method and device for transdermal administration of parathyroid hormone using a microprojection matrix |
US8337457B2 (en) | 2010-05-05 | 2012-12-25 | Springleaf Therapeutics, Inc. | Systems and methods for delivering a therapeutic agent |
US10384039B2 (en) | 2010-05-14 | 2019-08-20 | C. R. Bard, Inc. | Catheter insertion device including top-mounted advancement components |
US11925779B2 (en) | 2010-05-14 | 2024-03-12 | C. R. Bard, Inc. | Catheter insertion device including top-mounted advancement components |
US8932258B2 (en) | 2010-05-14 | 2015-01-13 | C. R. Bard, Inc. | Catheter placement device and method |
US9872971B2 (en) | 2010-05-14 | 2018-01-23 | C. R. Bard, Inc. | Guidewire extension system for a catheter placement device |
US9950139B2 (en) | 2010-05-14 | 2018-04-24 | C. R. Bard, Inc. | Catheter placement device including guidewire and catheter control elements |
WO2011156095A2 (en) | 2010-06-10 | 2011-12-15 | The Regents Of The University Of California | Textile-based printable electrodes for electrochemical sensing |
US9227021B2 (en) | 2010-06-29 | 2016-01-05 | Genesis Biosystems, Inc. | Microneedle roller (MNR) infusion system |
CN103068308B (en) | 2010-07-16 | 2016-03-16 | 第七感生物系统有限公司 | For the lower pressure environment of fluid conveying device |
US8814792B2 (en) | 2010-07-27 | 2014-08-26 | Carefusion 303, Inc. | System and method for storing and forwarding data from a vital-signs monitor |
US9585620B2 (en) | 2010-07-27 | 2017-03-07 | Carefusion 303, Inc. | Vital-signs patch having a flexible attachment to electrodes |
US9017255B2 (en) | 2010-07-27 | 2015-04-28 | Carefusion 303, Inc. | System and method for saving battery power in a patient monitoring system |
US9615792B2 (en) | 2010-07-27 | 2017-04-11 | Carefusion 303, Inc. | System and method for conserving battery power in a patient monitoring system |
US9055925B2 (en) | 2010-07-27 | 2015-06-16 | Carefusion 303, Inc. | System and method for reducing false alarms associated with vital-signs monitoring |
US9357929B2 (en) | 2010-07-27 | 2016-06-07 | Carefusion 303, Inc. | System and method for monitoring body temperature of a person |
US9420952B2 (en) | 2010-07-27 | 2016-08-23 | Carefusion 303, Inc. | Temperature probe suitable for axillary reading |
DE102010038733A1 (en) | 2010-07-30 | 2012-02-02 | Robert Bosch Gmbh | Modular microneedle transport device |
US20120039809A1 (en) | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Systems and techniques for monitoring subjects |
US9173994B2 (en) * | 2010-08-20 | 2015-11-03 | Purdue Research Foundation | Touch-actuated micropump for transdermal drug delivery and method of use |
KR20140039132A (en) | 2010-09-27 | 2014-04-01 | 스테디메드 리미티드 | Size-efficient drug-delivery device |
EP2915552A1 (en) | 2010-10-07 | 2015-09-09 | Massachusetts Institute of Technology | Injection methods using a servo-controlled needle-free injector |
JP5934710B2 (en) | 2010-10-07 | 2016-06-15 | マサチューセッツ インスティテュート オブ テクノロジー | Solid and / or fluid delivery using a Lorentz force direct acting needleless jet injection system |
EP2627292B1 (en) | 2010-10-15 | 2018-10-10 | Clearside Biomedical, Inc. | Device for ocular access |
WO2012058192A1 (en) * | 2010-10-26 | 2012-05-03 | 7944942 Canada Inc. | Automatic medication injection device |
US9017289B2 (en) | 2010-11-03 | 2015-04-28 | Covidien Lp | Transdermal fluid delivery device |
US8808202B2 (en) | 2010-11-09 | 2014-08-19 | Seventh Sense Biosystems, Inc. | Systems and interfaces for blood sampling |
CA2821979A1 (en) | 2010-12-17 | 2012-06-21 | Yet-Ming Chiang | Electrochemical actuators |
US8690833B2 (en) | 2011-01-31 | 2014-04-08 | Vascular Pathways, Inc. | Intravenous catheter and insertion device with reduced blood spatter |
CN204364557U (en) | 2011-02-09 | 2015-06-03 | 贝克顿·迪金森公司 | Inject tackling |
EP2678065B1 (en) | 2011-02-25 | 2019-09-11 | C.R. Bard Inc. | Medical component insertion device including a retractable needle |
US8696637B2 (en) | 2011-02-28 | 2014-04-15 | Kimberly-Clark Worldwide | Transdermal patch containing microneedles |
US10136845B2 (en) | 2011-02-28 | 2018-11-27 | Abbott Diabetes Care Inc. | Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same |
CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
WO2012139593A2 (en) * | 2011-04-15 | 2012-10-18 | Rigshospitalet Copenhagen University Hospital | System and method for injecting a substance into a human body |
BR112013027010A2 (en) * | 2011-04-19 | 2016-12-27 | Invisiderm Llc | method of producing substances with supersaturated gas, device for their transdermal delivery, and their uses |
SG194536A1 (en) * | 2011-04-19 | 2013-12-30 | Invisiderm Llc | Method of producing substances with supersaturated gas,transdermal delivery device thereof, and uses thereof |
US20130158468A1 (en) * | 2011-12-19 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
AU2012249692A1 (en) | 2011-04-29 | 2013-11-14 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving fluids |
CN103874461B (en) | 2011-04-29 | 2017-05-10 | 第七感生物系统有限公司 | Devices for collection and/or manipulation of blood spots or other bodily fluids |
USD903101S1 (en) | 2011-05-13 | 2020-11-24 | C. R. Bard, Inc. | Catheter |
US8636696B2 (en) * | 2011-06-10 | 2014-01-28 | Kimberly-Clark Worldwide, Inc. | Transdermal device containing microneedles |
EP2729148A4 (en) | 2011-07-06 | 2015-04-22 | Parkinson S Inst | Compositions and methods for treatment of symptoms in parkinson's disease patients |
WO2013058879A2 (en) | 2011-09-02 | 2013-04-25 | The Regents Of The University Of California | Microneedle arrays for biosensing and drug delivery |
EP2771059B1 (en) | 2011-10-27 | 2019-07-17 | Sorrento Therapeutics, Inc. | Transdermal delivery of high viscosity bioactive agents |
US20170246439A9 (en) | 2011-10-27 | 2017-08-31 | Kimberly-Clark Worldwide, Inc. | Increased Bioavailability of Transdermally Delivered Agents |
KR20140079429A (en) | 2011-10-27 | 2014-06-26 | 킴벌리-클라크 월드와이드, 인크. | Implantable devices for delivery of bioactive agents |
SG10201508662SA (en) | 2011-10-28 | 2015-11-27 | Presage Biosciences Inc | Methods for drug delivery |
US9317656B2 (en) | 2011-11-23 | 2016-04-19 | Abbott Diabetes Care Inc. | Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof |
JP2015501844A (en) | 2011-12-16 | 2015-01-19 | モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. | Modified nucleosides, nucleotides and nucleic acid compositions |
DE102011089723A1 (en) * | 2011-12-23 | 2013-06-27 | Robert Bosch Gmbh | Microneedle array applicator and method of applying a microneedle array |
US10130800B2 (en) | 2012-01-27 | 2018-11-20 | Invisiderm, Llc | Method of producing substances with supersaturated gas, transdermal delivery device thereof, and uses thereof |
WO2013136185A2 (en) | 2012-03-13 | 2013-09-19 | Becton Dickinson France | Method of manufacture for a miniaturized drug delivery device |
EP2825225B1 (en) | 2012-03-15 | 2018-05-09 | Steadymed Ltd. | Enhanced infusion-site pain-reduction for drug-delivery devices |
WO2013140395A1 (en) | 2012-03-19 | 2013-09-26 | Steadymed Ltd. | Fluid-connection mechanism for patch-pumps |
KR20130114996A (en) * | 2012-04-10 | 2013-10-21 | 삼성디스플레이 주식회사 | Display apparatus and fabricating method thereof |
US9944019B2 (en) | 2012-05-01 | 2018-04-17 | University of Pittsburgh—of the Commonwealth System of Higher Education | Tip-loaded microneedle arrays for transdermal insertion |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US9555186B2 (en) | 2012-06-05 | 2017-01-31 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
EP2872222B1 (en) * | 2012-07-06 | 2023-05-31 | The General Hospital Corporation | Method and apparatus for dermatological treatment |
US9782538B2 (en) | 2012-09-27 | 2017-10-10 | Becton, Dickinson And Company | Angled inserter for drug infusion |
KR20210133321A (en) | 2012-11-08 | 2021-11-05 | 클리어사이드 바이오메디컬, 인코포레이드 | Methods and devices for the treatment of ocular disease in human subjects |
HRP20220607T1 (en) | 2012-11-26 | 2022-06-24 | Modernatx, Inc. | Terminally modified rna |
CA2896188C (en) | 2012-12-21 | 2021-02-23 | Corium International, Inc. | Microarray for delivery of therapeutic agent and methods of use |
JP2016504050A (en) | 2013-01-17 | 2016-02-12 | モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. | Signal sensor polynucleotide for modification of cell phenotype |
US10105487B2 (en) | 2013-01-24 | 2018-10-23 | Chrono Therapeutics Inc. | Optimized bio-synchronous bioactive agent delivery system |
US9522254B2 (en) | 2013-01-30 | 2016-12-20 | Vascular Pathways, Inc. | Systems and methods for venipuncture and catheter placement |
BR112015020328B1 (en) * | 2013-02-28 | 2022-05-31 | Sorrento Therapeutics, Inc | Transdermal drug delivery device |
AU2014249471B2 (en) | 2013-03-12 | 2019-01-24 | Corium Pharma Solutions, Inc. | Microprojection applicators |
EP2968391A1 (en) | 2013-03-13 | 2016-01-20 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
JP6098250B2 (en) * | 2013-03-14 | 2017-03-22 | セイコーエプソン株式会社 | Liquid transport device |
US10080839B2 (en) | 2013-03-14 | 2018-09-25 | Becton, Dickinson And Company | Angled inserter for drug infusion |
MX2015012933A (en) | 2013-03-15 | 2016-09-19 | Corium Int Inc | Microarray for delivery of therapeutic agent and methods of use. |
ES2939317T3 (en) * | 2013-03-15 | 2023-04-20 | Corium Pharma Solutions Inc | Multi-impact micro-spray applicators |
US9603995B2 (en) | 2013-03-15 | 2017-03-28 | Tandem Diabetes Care. Inc. | Device and method for setting therapeutic parameters for an infusion device |
CA2903495C (en) * | 2013-03-15 | 2021-05-25 | Amgen Inc. | Body contour adaptable autoinjector device |
US9821113B2 (en) | 2013-03-15 | 2017-11-21 | Becton, Dickinson And Company | Automatic angled infusion set assembly |
CA2903763C (en) | 2013-03-15 | 2021-11-16 | Corium International, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
WO2014179698A2 (en) | 2013-05-03 | 2014-11-06 | Clearside Biomedical, Inc. | Apparatus and methods for ocular injection |
US20140350518A1 (en) | 2013-05-23 | 2014-11-27 | Allergan, Inc. | Syringe extrusion accessory |
US20140350516A1 (en) | 2013-05-23 | 2014-11-27 | Allergan, Inc. | Mechanical syringe accessory |
US10188550B2 (en) | 2013-06-03 | 2019-01-29 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
US9907970B2 (en) | 2013-06-14 | 2018-03-06 | Cardiothrive, Inc. | Therapeutic system and method using biphasic or multiphasic pulse waveform |
US9656094B2 (en) | 2013-06-14 | 2017-05-23 | Cardiothrive, Inc. | Biphasic or multiphasic pulse generator and method |
US10149973B2 (en) | 2013-06-14 | 2018-12-11 | Cardiothrive, Inc. | Multipart non-uniform patient contact interface and method of use |
US10279189B2 (en) | 2013-06-14 | 2019-05-07 | Cardiothrive, Inc. | Wearable multiphasic cardioverter defibrillator system and method |
US9616243B2 (en) | 2013-06-14 | 2017-04-11 | Cardiothrive, Inc. | Dynamically adjustable multiphasic defibrillator pulse system and method |
US9833630B2 (en) | 2013-06-14 | 2017-12-05 | Cardiothrive, Inc. | Biphasic or multiphasic pulse waveform and method |
JP6038311B2 (en) | 2013-06-18 | 2016-12-07 | 久光製薬株式会社 | applicator |
JP6038310B2 (en) | 2013-06-19 | 2016-12-07 | 久光製薬株式会社 | applicator |
US20150027241A1 (en) * | 2013-07-23 | 2015-01-29 | Diba Industries, Inc. | Piercing probes with offset conical piercing tip and fluid-sampling systems comprising the piercing probes |
US10299793B2 (en) | 2013-10-23 | 2019-05-28 | Valtech Cardio, Ltd. | Anchor magazine |
EP3082760A1 (en) | 2013-12-19 | 2016-10-26 | Novartis AG | LEPTIN mRNA COMPOSITIONS AND FORMULATIONS |
WO2015119906A1 (en) | 2014-02-05 | 2015-08-13 | Amgen Inc. | Drug delivery system with electromagnetic field generator |
GB201403773D0 (en) * | 2014-03-04 | 2014-04-16 | Univ Cardiff | Microneedle based cell delivery |
US10279106B1 (en) | 2014-05-08 | 2019-05-07 | Tandem Diabetes Care, Inc. | Insulin patch pump |
US10029048B2 (en) | 2014-05-13 | 2018-07-24 | Allergan, Inc. | High force injection devices |
EP3151883A1 (en) | 2014-06-03 | 2017-04-12 | Amgen Inc. | Devices and methods for assisting a user of a drug delivery device |
CN106794321A (en) | 2014-06-20 | 2017-05-31 | 科尼尔赛德生物医学公司 | Variable-diameter intubation and for controlling the method to the insertion depth of drug delivery |
US10321858B2 (en) | 2014-08-18 | 2019-06-18 | Proteadx, Inc. | Apparatus and methods for transdermal sensing of analytes in interstitial fluid and associated data transmission systems |
US10624843B2 (en) | 2014-09-04 | 2020-04-21 | Corium, Inc. | Microstructure array, methods of making, and methods of use |
US10232146B2 (en) | 2014-09-05 | 2019-03-19 | C. R. Bard, Inc. | Catheter insertion device including retractable needle |
EP3193973A1 (en) * | 2014-09-15 | 2017-07-26 | Sanofi | Medicament delivery device with rotatable housing on a base |
DE102014219719B4 (en) * | 2014-09-29 | 2018-05-03 | Ipr Intelligente Peripherien Für Roboter Gmbh | needle grippers |
US10226585B2 (en) | 2014-10-01 | 2019-03-12 | Allergan, Inc. | Devices for injection and dosing |
USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
CN105873514B (en) * | 2014-10-27 | 2018-10-26 | 深圳市光聚通讯技术开发有限公司 | Dynamic glucose harvester and host |
US10799630B2 (en) | 2014-12-19 | 2020-10-13 | Amgen Inc. | Drug delivery device with proximity sensor |
EP3689394A1 (en) | 2014-12-19 | 2020-08-05 | Amgen Inc. | Drug delivery device with live button or user interface field |
CA2971853A1 (en) | 2014-12-23 | 2016-06-30 | Abraham Hasarchi | Harmonizing noise aggregation and noise management in distributed antenna system |
EP3045185A1 (en) * | 2015-01-16 | 2016-07-20 | Sanofi-Aventis Deutschland GmbH | Connector for a container filled with a liquid medicament |
WO2016123406A1 (en) | 2015-01-28 | 2016-08-04 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
EP3556411B1 (en) | 2015-02-17 | 2021-06-30 | Amgen Inc. | Drug delivery device with vacuum assisted securement and/or feedback |
EP3268063A4 (en) | 2015-03-10 | 2018-10-31 | Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company | Multiple needle injector |
CA2977814A1 (en) | 2015-03-12 | 2016-09-15 | Chrono Therapeutics Inc. | Craving input and support system |
WO2016149673A1 (en) | 2015-03-18 | 2016-09-22 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Bioactive components conjugated to substrates of microneedle arrays |
USD903100S1 (en) | 2015-05-01 | 2020-11-24 | C. R. Bard, Inc. | Catheter placement device |
JP6784352B2 (en) * | 2015-05-11 | 2020-11-11 | 国立大学法人 東京医科歯科大学 | Insulin delivery device |
CN107708769B (en) | 2015-05-15 | 2021-07-27 | C·R·巴德股份有限公司 | Catheter placement device including extendable needle safety feature |
US10463847B2 (en) | 2015-06-11 | 2019-11-05 | Steadymed Ltd. | Infusion set |
WO2017004067A1 (en) | 2015-06-29 | 2017-01-05 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
US10940292B2 (en) | 2015-07-08 | 2021-03-09 | Actuated Medical, Inc. | Reduced force device for intravascular access and guidewire placement |
US11793543B2 (en) | 2015-09-18 | 2023-10-24 | Obvius Robotics, Inc. | Device and method for automated insertion of penetrating member |
WO2017066768A1 (en) | 2015-10-16 | 2017-04-20 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices |
WO2017120322A1 (en) | 2016-01-05 | 2017-07-13 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Skin microenvironment targeted delivery for promoting immune and other responses |
EP3413851B1 (en) | 2016-02-10 | 2023-09-27 | Clearside Biomedical, Inc. | Packaging |
WO2017143153A1 (en) | 2016-02-19 | 2017-08-24 | North Carolina State University | Methods and compositions related to physiologically responsive microneedle delivery systems |
EA038691B1 (en) | 2016-03-28 | 2021-10-05 | Айкор Медикэл Системс, Инк. | Apparatus for delivery of therapeutic agents |
EP3439716B1 (en) | 2016-04-08 | 2023-11-01 | Allergan, Inc. | Aspiration and injection device |
EP3452165A1 (en) | 2016-05-02 | 2019-03-13 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
WO2017198872A1 (en) * | 2016-05-20 | 2017-11-23 | Uprax | System and method for applying microneedles |
NL2016807B1 (en) * | 2016-05-20 | 2017-11-27 | Uprax | System and method for applying microneedles |
US10220195B2 (en) * | 2016-06-08 | 2019-03-05 | Eclipse Medcorp, Llc | Radio frequency needling device for use with disposable needle cartridges |
WO2018031913A1 (en) | 2016-08-12 | 2018-02-15 | Clearside Biomedical, Inc. | Devices and methods for adjusting the insertion depth of a needle for medicament delivery |
CN112206397B (en) | 2016-09-12 | 2023-03-21 | C·R·巴德股份有限公司 | Blood control of catheter insertion device |
US11241563B2 (en) | 2016-12-22 | 2022-02-08 | Johnson & Johnson Consumer Inc. | Microneedle arrays and methods for making and using |
EP3338832A1 (en) | 2016-12-23 | 2018-06-27 | Sanofi-Aventis Deutschland GmbH | Medicament delivery device |
JP2020503950A (en) | 2017-01-06 | 2020-02-06 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | Device and method for transdermal drug delivery |
EP3585471A4 (en) | 2017-03-01 | 2021-03-10 | C.R. Bard, Inc. | Catheter insertion device |
USD867582S1 (en) | 2017-03-24 | 2019-11-19 | Allergan, Inc. | Syringe device |
WO2019100901A1 (en) * | 2017-11-27 | 2019-05-31 | 苏州纳通生物纳米技术有限公司 | Disposable self-destructive vibration head assembly and penetration-enhancing instrument using same |
US10828500B2 (en) | 2017-12-22 | 2020-11-10 | Cardiothrive, Inc. | External defibrillator |
CN111818953A (en) * | 2018-01-07 | 2020-10-23 | 亚夫拉罕·阿米尔 | High-load microneedles and compositions for skin improvement |
BR112020017215A2 (en) | 2018-03-07 | 2020-12-22 | Bard Access Systems, Inc. | GUIDELINE ADVANCE SYSTEMS AND REVERSE BLOOD SQUEEZE FOR A MEDICAL DEVICE INSERT SYSTEM |
US11090506B2 (en) * | 2018-05-15 | 2021-08-17 | Omm Imports, Inc. | Disposable product cap and assembly having a manually usable thermo-optical device for skin care |
WO2019232077A1 (en) | 2018-05-29 | 2019-12-05 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
KR20210025601A (en) | 2018-06-29 | 2021-03-09 | 존슨 앤드 존슨 컨수머 인코포레이티드 | Three-dimensional microfluidic device for delivery of active agents |
USD921884S1 (en) | 2018-07-27 | 2021-06-08 | Bard Access Systems, Inc. | Catheter insertion device |
FR3084578B1 (en) * | 2018-08-03 | 2024-01-12 | Pkvitality | MANAGEMENT OF MICRONEEDLE INVESTMENT |
EP3927394A1 (en) | 2019-02-22 | 2021-12-29 | DEKA Products Limited Partnership | Infusion set and inserter assembly systems and methods |
US20220134072A1 (en) * | 2019-03-19 | 2022-05-05 | King Abdullah University Of Science And Technology | Miniaturized delivery system and method |
US11590332B2 (en) * | 2019-04-17 | 2023-02-28 | Path Scientific, Llc | Precision microneedling device and methods of use |
GB201908043D0 (en) * | 2019-06-05 | 2019-07-17 | Lekkos Vasileios | Transdermal patch for therapeutic uses |
KR102279603B1 (en) * | 2019-06-11 | 2021-07-20 | (주)비올 | Needle assembly, skin stimulator including the same, and manufacturing method thereof |
CN114364976A (en) * | 2019-07-12 | 2022-04-15 | 曲莱博医疗有限公司 | Electrochemical FET sensor |
WO2021020730A2 (en) * | 2019-07-26 | 2021-02-04 | 주식회사 림사이언스 | Apparatus for applying pressure to medical needle |
CN112386778A (en) | 2019-08-19 | 2021-02-23 | 贝克顿·迪金森公司 | Midline catheter placement device |
WO2021087249A1 (en) * | 2019-10-30 | 2021-05-06 | Thermalin, Inc. | Agent delivery systems, devices, and methods |
EP4108286A4 (en) * | 2020-02-20 | 2024-03-13 | Jubilee Biotech Co Ltd | Applicator for drug delivery and microneedle patch used therefor |
DK4048152T3 (en) | 2020-07-29 | 2024-03-11 | Biolinq Incorporated | SYSTEM FOR CONTINUOUS ANALYTE MONITORING WITH MICRON NEEDLE ARRANGEMENT |
CN112370653B (en) * | 2020-11-12 | 2022-08-30 | 深圳市圣通生物科技有限公司 | Spray disinfection type nanometer microneedle mesoderm leading-in beauty instrument |
US20220273352A1 (en) * | 2021-03-01 | 2022-09-01 | Bluexthermal, Inc. | Device and method for thermal modulation of tissue |
US11452474B1 (en) | 2021-04-14 | 2022-09-27 | Satio, Inc. | Dual lever dermal patch system |
CN116113454A (en) | 2021-05-08 | 2023-05-12 | 比奥林股份有限公司 | Continuous analyte monitoring device fault detection based on microneedle arrays |
US11877848B2 (en) | 2021-11-08 | 2024-01-23 | Satio, Inc. | Dermal patch for collecting a physiological sample |
US11510602B1 (en) | 2021-11-08 | 2022-11-29 | Satio, Inc. | Dermal patch for collecting a physiological sample |
EP4295873A1 (en) * | 2022-06-21 | 2023-12-27 | National University of Ireland Galway | An infusion catheter system |
Family Cites Families (144)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US447225A (en) * | 1891-02-24 | Machine for attaching stays to the corners of boxes | ||
US3659A (en) * | 1844-07-11 | Machine for hulling and pearling rice | ||
US3537A (en) | 1844-04-13 | X g gupping instrument | ||
US1934043A (en) * | 1929-05-17 | 1933-11-07 | Standard Oil Dev Co | Process of improvement of lubricating oils |
DE596981C (en) | 1931-10-30 | 1934-05-12 | Mario Demarchi Dr | Injection syringe |
FR757501A (en) | 1932-09-23 | 1933-12-28 | Automatic device for handling injection syringes | |
US2088780A (en) | 1936-10-09 | 1937-08-03 | Sigurd E Follese | Massage device |
US2763935A (en) | 1954-06-11 | 1956-09-25 | Purdne Res Foundation | Determining depth of layers of fat and of muscle on an animal body |
US2945496A (en) | 1958-08-18 | 1960-07-19 | Fosdal Alfred | Dental instrument for immobilizing tissue |
DE1115722B (en) | 1960-04-30 | 1961-10-26 | Hoechst Ag | Metal anode for the electrolytic separation of chlorine |
GB1128329A (en) | 1964-12-23 | 1968-09-25 | Nat Res Dev | Electrodes for making electrical contact to the living body of a mammal |
US3568735A (en) * | 1968-06-26 | 1971-03-09 | Cooke Eng Co | Laboratory microtitration dispensing apparatus |
US3568732A (en) | 1969-02-28 | 1971-03-09 | Kelly James A Jun | Splice straightener for aerial conductors |
US3659600A (en) | 1970-02-24 | 1972-05-02 | Estin Hans H | Magnetically operated capsule for administering drugs |
US3727614A (en) | 1971-05-13 | 1973-04-17 | Merck & Co Inc | Multiple dosage inoculator |
US3964482A (en) | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
US3738493A (en) | 1971-09-24 | 1973-06-12 | Analytical Instr Spec | Apparatus for simultaneous application of samples to thin layer chromatography plates |
BE795384A (en) | 1972-02-14 | 1973-08-13 | Ici Ltd | DRESSINGS |
CH557178A (en) | 1972-08-10 | 1974-12-31 | Siemens Ag | DEVICE FOR DISPENSING DRUGS. |
US3923060A (en) | 1974-04-23 | 1975-12-02 | Jr Everett H Ellinwood | Apparatus and method for implanted self-powered medication dispensing having timing and evaluator means |
US4140109A (en) | 1977-10-17 | 1979-02-20 | Savic Michael I | Impedance-based method and apparatus for monitoring cryodestruction in controlled cryosurgery |
FR2460343A1 (en) | 1979-06-29 | 1981-01-23 | Solvay | CATHODE FOR THE ELECTROLYTIC PRODUCTION OF HYDROGEN |
JPS5683360A (en) * | 1979-12-10 | 1981-07-07 | Olympus Optical Co | Pneumoperitoneum needle |
US4447225A (en) | 1982-03-22 | 1984-05-08 | Taff Barry E | Multidose jet injector |
US4619652A (en) | 1982-12-23 | 1986-10-28 | Alza Corporation | Dosage form for use in a body mounted pump |
US4505710A (en) | 1983-05-13 | 1985-03-19 | Collins Earl R | Implantable fluid dispensing system |
DE3502913C1 (en) | 1985-01-29 | 1986-07-03 | Günter Prof. Dr.rer.nat. 5100 Aachen Rau | Sensor for non-invasive detection of electrophysiological values |
US4777599A (en) | 1985-02-26 | 1988-10-11 | Gillette Company | Viscoelastometry of skin using shear wave propagation |
FR2594341B1 (en) * | 1986-02-14 | 1990-08-10 | Charton Jean Pierre | INJECTOR APPARATUS FOR THE PRACTICE OF MESOTHERAPY |
AT384737B (en) | 1986-04-04 | 1987-12-28 | Thoma Dipl Ing Dr Techn Herwig | DEVICE FOR CONTINUOUSLY DELIVERING LIQUID MEDICINAL PRODUCTS |
AU7847487A (en) * | 1986-09-18 | 1988-02-04 | Selfridge, A.R. | Cannulation of blood vessels |
CA1283827C (en) | 1986-12-18 | 1991-05-07 | Giorgio Cirelli | Appliance for injection of liquid formulations |
US4808156A (en) | 1987-03-09 | 1989-02-28 | Dean Consuelo M | Cannular instrument and method for inserting a cannular instrument into a vein |
US6056716A (en) | 1987-06-08 | 2000-05-02 | D'antonio Consultants International Inc. | Hypodermic fluid dispenser |
DD262803A1 (en) | 1987-08-05 | 1988-12-14 | Transform Roentgen Matern Veb | INJECTION DEVICE |
US5312486A (en) | 1987-12-24 | 1994-05-17 | Frank Meyer | Water-containing, hardenable foam compositions with inorganic components and process for their preparation |
US4989614A (en) | 1988-02-23 | 1991-02-05 | Vance Products Incorporated | Fine-needle aspiration cell sampling methods |
CA2008262A1 (en) * | 1989-01-30 | 1990-07-30 | John A. Gilly | Clinical applicator |
US5425706A (en) | 1989-02-24 | 1995-06-20 | S. I. Scientific Innovations Ltd. | Dispensing device particularly useful for dispensing nutritional liquids |
US5062834A (en) | 1989-02-24 | 1991-11-05 | Product Development (S.G.Z.) Ltd | Device for dispensing a liquid particularly useful for delivering medicaments at a predetermined rate |
JPH0648975B2 (en) | 1989-10-02 | 1994-06-29 | 俊郎 樋口 | Micro injection device and injection control method thereof |
US5262128A (en) | 1989-10-23 | 1993-11-16 | The United States Of America As Represented By The Department Of Health And Human Services | Array-type multiple cell injector |
EP0429842B1 (en) | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US5697901A (en) | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
US6090790A (en) | 1989-12-14 | 2000-07-18 | Eriksson; Elof | Gene delivery by microneedle injection |
US5092901A (en) | 1990-06-06 | 1992-03-03 | The Royal Institution For The Advancement Of Learning (Mcgill University) | Shape memory alloy fibers having rapid twitch response |
US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
US5156591A (en) | 1990-12-13 | 1992-10-20 | S. I. Scientific Innovations Ltd. | Skin electrode construction and transdermal drug delivery device utilizing same |
TW279133B (en) | 1990-12-13 | 1996-06-21 | Elan Med Tech | |
US5279544A (en) * | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
US5279547A (en) | 1991-01-03 | 1994-01-18 | Alcon Surgical Inc. | Computer controlled smart phacoemulsification method and apparatus |
SE9101022D0 (en) * | 1991-01-09 | 1991-04-08 | Paal Svedman | MEDICAL SUSPENSION DEVICE |
US5312456A (en) | 1991-01-31 | 1994-05-17 | Carnegie Mellon University | Micromechanical barb and method for making the same |
AU664214B2 (en) | 1991-11-13 | 1995-11-09 | Elan Corporation, Plc | Drug delivery device |
US6048337A (en) | 1992-01-07 | 2000-04-11 | Principal Ab | Transdermal perfusion of fluids |
KR0145453B1 (en) | 1992-01-21 | 1998-07-01 | 알렌 제이 | Electrosurgical trocar control device |
US5252023A (en) * | 1992-02-10 | 1993-10-12 | Kelly Kevin M | Lifting apparatus |
JP2572823Y2 (en) | 1992-02-13 | 1998-05-25 | 株式会社アドバンス | Simple blood sampler |
AU4282793A (en) | 1992-04-10 | 1993-11-18 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University | A microneedle for injection of ocular blood vessels |
US5478328A (en) | 1992-05-22 | 1995-12-26 | Silverman; David G. | Methods of minimizing disease transmission by used hypodermic needles, and hypodermic needles adapted for carrying out the method |
JPH0698920A (en) * | 1992-09-21 | 1994-04-12 | Hayashi Shigetada | Acupuncture precise measuring instrument |
US5354273A (en) | 1992-12-14 | 1994-10-11 | Mallinckrodt Medical, Inc. | Delivery apparatus with pressure controlled delivery |
US5478323A (en) * | 1993-04-02 | 1995-12-26 | Eli Lilly And Company | Manifold for injection apparatus |
IE68890B1 (en) | 1993-04-08 | 1996-07-24 | Elan Med Tech | Intradermal delivery device |
US5335668A (en) * | 1993-04-30 | 1994-08-09 | Medical Scientific, Inc. | Diagnostic impedance measuring system for an insufflation needle |
JP3494183B2 (en) * | 1993-08-10 | 2004-02-03 | 株式会社アドバンス | Simple blood collection device |
CA2171563A1 (en) | 1993-09-14 | 1995-03-23 | Eric Le Cheminant | Injection device |
US5389222A (en) | 1993-09-21 | 1995-02-14 | The United States Of America As Represented By The United States Department Of Energy | Spring-loaded polymeric gel actuators |
US5599345A (en) | 1993-11-08 | 1997-02-04 | Zomed International, Inc. | RF treatment apparatus |
US5997501A (en) | 1993-11-18 | 1999-12-07 | Elan Corporation, Plc | Intradermal drug delivery device |
US5611806A (en) | 1994-05-23 | 1997-03-18 | Samsung Electro-Mechanics Co., Ltd. | Skin perforating device for transdermal medication |
CA2149836C (en) | 1994-05-23 | 1999-07-06 | Sang Bae Choi | Perforating device for dermal administration |
US5591139A (en) | 1994-06-06 | 1997-01-07 | The Regents Of The University Of California | IC-processed microneedles |
DE4420232A1 (en) | 1994-06-07 | 1995-12-14 | Robert Waltereit | Penetration depth checking device for hollow needle or probe inserted in human or animal patient |
US5649423A (en) | 1994-06-07 | 1997-07-22 | Sandia Corporation | Micromechanism linear actuator with capillary force sealing |
US5478315A (en) | 1994-08-08 | 1995-12-26 | Brothers Family Investments, L.C. | Local anesthetic injection system |
US5432098A (en) | 1994-10-31 | 1995-07-11 | Dynatech Precision Sampling Corporation | Apparatus, and process, for automatically sampling solids and semi-solids materials for analysis |
IE72524B1 (en) * | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
GB9508606D0 (en) | 1995-04-27 | 1995-06-14 | Svedman Paul | Suction blister sampling |
AU5869796A (en) | 1995-05-22 | 1996-12-11 | Ned A. Godshall | Micromechanical patch for enhancing the delivery of compound s through the skin |
AU5740496A (en) | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
US5827216A (en) | 1995-06-07 | 1998-10-27 | Cormedics Corp. | Method and apparatus for accessing the pericardial space |
ZA9610374B (en) * | 1995-12-11 | 1997-06-23 | Elan Med Tech | Cartridge-based drug delivery device |
JPH09192218A (en) * | 1996-01-16 | 1997-07-29 | Hitachi Ltd | Blood-sugar level control system |
JPH09239031A (en) * | 1996-03-09 | 1997-09-16 | Honda Electron Co Ltd | Injector mounting ultrasonic vibrator transducer |
US5843016A (en) | 1996-03-18 | 1998-12-01 | Physion S.R.L. | Electromotive drug administration for treatment of acute urinary outflow obstruction |
US6117155A (en) | 1996-05-01 | 2000-09-12 | Lee; Young H. | Coated needle for use with an intramuscular stimulation treatment device |
US5785688A (en) | 1996-05-07 | 1998-07-28 | Ceramatec, Inc. | Fluid delivery apparatus and method |
US5954668A (en) | 1996-06-14 | 1999-09-21 | Medrad, Inc. | Extravasation detector using microwave radiometry |
US6230051B1 (en) * | 1996-06-18 | 2001-05-08 | Alza Corporation | Device for enhancing transdermal agent delivery or sampling |
US6183434B1 (en) | 1996-07-03 | 2001-02-06 | Spectrx, Inc. | Multiple mechanical microporation of skin or mucosa |
JPH1043296A (en) * | 1996-08-05 | 1998-02-17 | Terumo Corp | Chemical injecting apparatus |
DE69718495T2 (en) | 1996-09-17 | 2003-11-20 | Deka Products Lp | SYSTEM FOR DISPOSAL OF MEDICINE BY TRANSPORT |
US6071249A (en) | 1996-12-06 | 2000-06-06 | Abbott Laboratories | Method and apparatus for obtaining blood for diagnostic tests |
SE9604564D0 (en) | 1996-12-12 | 1996-12-12 | Paal Svedman | Method and apparatus for conducting electrical currents |
US6246904B1 (en) | 1996-12-17 | 2001-06-12 | Alza Corporation | Electrotransport drug delivery reservoirs containing inert fillers |
US5928194A (en) | 1997-04-07 | 1999-07-27 | Maget; Henri J. R. | Self-contained liquid microdispenser |
US5928207A (en) | 1997-06-30 | 1999-07-27 | The Regents Of The University Of California | Microneedle with isotropically etched tip, and method of fabricating such a device |
US5972013A (en) | 1997-09-19 | 1999-10-26 | Comedicus Incorporated | Direct pericardial access device with deflecting mechanism and method |
JPH11137684A (en) * | 1997-11-12 | 1999-05-25 | Hiroshi Oya | Indolent and safe syringe |
AU752222B2 (en) * | 1997-11-26 | 2002-09-12 | E-Z-Em, Inc. | Extravasation detection technique |
US6918901B1 (en) * | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
DK1037686T3 (en) | 1997-12-11 | 2006-01-02 | Alza Corp | Apparatus for enhancing transdermal flow of agents |
ATE221400T1 (en) | 1997-12-11 | 2002-08-15 | Alza Corp | DEVICE FOR INCREASE THE TRANSDERMAL FLOW OF ACTIVE INGREDIENTS |
US6126629A (en) | 1997-12-18 | 2000-10-03 | Bausch & Lomb Surgical, Inc. | Multiple port phaco needle |
US6154673A (en) * | 1997-12-30 | 2000-11-28 | Agilent Technologies, Inc. | Multilingual defibrillator |
US6048204A (en) * | 1998-02-03 | 2000-04-11 | Lifecore Biomedical, Inc. | Self tapping screw type dental implant |
US5957895A (en) | 1998-02-20 | 1999-09-28 | Becton Dickinson And Company | Low-profile automatic injection device with self-emptying reservoir |
US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
US5971998A (en) | 1998-03-31 | 1999-10-26 | Donald G. Russell | Support device and method for controlling breast thickness during stereotactic guided needle biopsy |
CA2311487C (en) | 1998-05-13 | 2004-02-10 | Cygnus, Inc. | Signal processing for measurement of physiological analytes |
CA2332112C (en) | 1998-05-13 | 2004-02-10 | Cygnus, Inc. | Monitoring of physiological analytes |
CA2334174A1 (en) | 1998-06-04 | 1999-12-09 | Izrail Tsals | Gas driven drug delivery device |
EP1086214B1 (en) | 1998-06-10 | 2009-11-25 | Georgia Tech Research Corporation | Microneedle devices and methods of their manufacture |
US6678556B1 (en) | 1998-07-13 | 2004-01-13 | Genetronics, Inc. | Electrical field therapy with reduced histopathological change in muscle |
GB9815819D0 (en) | 1998-07-22 | 1998-09-16 | Secr Defence | Transferring materials into cells and a microneedle array |
GB9815820D0 (en) | 1998-07-22 | 1998-09-16 | Secr Defence | Improvements relating to micro-machining |
JP2002521147A (en) | 1998-07-27 | 2002-07-16 | メディ−ジェクト コーポレイション | Loading mechanism for use in medical syringe assemblies |
CA2344398A1 (en) | 1998-09-18 | 2000-03-30 | The University Of Utah | Surface micromachined microneedles |
DE19843733A1 (en) | 1998-09-24 | 2000-03-30 | Voith Sulzer Papiertech Patent | Wiper blade assembly coating paper or card bands with optionally-viscous liquid, employs system of leaf spring tensioning which forms ductor chamber and is readily replaced and adjusted |
US6148232A (en) | 1998-11-09 | 2000-11-14 | Elecsys Ltd. | Transdermal drug delivery and analyte extraction |
US6317630B1 (en) | 1999-01-29 | 2001-11-13 | Yossi Gross | Drug delivery device |
US6132449A (en) | 1999-03-08 | 2000-10-17 | Agilent Technologies, Inc. | Extraction and transportation of blood for analysis |
US6319230B1 (en) | 1999-05-07 | 2001-11-20 | Scimed Life Systems, Inc. | Lateral needle injection apparatus and method |
CA2376128C (en) | 1999-06-04 | 2009-01-06 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
US6611707B1 (en) | 1999-06-04 | 2003-08-26 | Georgia Tech Research Corporation | Microneedle drug delivery device |
US6379324B1 (en) | 1999-06-09 | 2002-04-30 | The Procter & Gamble Company | Intracutaneous microneedle array apparatus |
US6256533B1 (en) | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
US6607495B1 (en) * | 1999-06-18 | 2003-08-19 | University Of Virginia Patent Foundation | Apparatus for fluid transport and related method thereof |
US6408204B1 (en) | 1999-07-28 | 2002-06-18 | Medrad, Inc. | Apparatuses and methods for extravasation detection |
ES2248165T3 (en) * | 1999-11-15 | 2006-03-16 | Velcro Industries B.V. | SKIN FIXING ELEMENT. |
CA2394171A1 (en) * | 1999-12-16 | 2001-06-21 | Alza Corporation | Device for enhancing transdermal flux of sampled agents |
US7003336B2 (en) * | 2000-02-10 | 2006-02-21 | Medtronic Minimed, Inc. | Analyte sensor method of making the same |
US6572740B2 (en) | 2000-04-13 | 2003-06-03 | Elan Pharma International Limited | Electrolytic cell |
US6565532B1 (en) | 2000-07-12 | 2003-05-20 | The Procter & Gamble Company | Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup |
US6440096B1 (en) * | 2000-07-14 | 2002-08-27 | Becton, Dickinson And Co. | Microdevice and method of manufacturing a microdevice |
JP2002028247A (en) * | 2000-07-18 | 2002-01-29 | Japan Science & Technology Corp | Method and instrument for sensing venous pricking by puncture needle |
CA2430590C (en) | 2000-11-30 | 2012-08-14 | Biovalve Technologies, Inc. | Fluid delivery and measurement systems and methods |
AU2002345757A1 (en) | 2001-06-11 | 2002-12-23 | Glaxo Group Limited | Medicament dispenser for containers of varying sizes |
US6835193B2 (en) | 2001-07-10 | 2004-12-28 | Myocardial Therapeutics, Inc. | Methods for controlled depth injections into interior body cavities |
US7429258B2 (en) | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
AU2002360712A1 (en) * | 2001-12-21 | 2003-07-30 | The Trustees Of Columbia University In The City Of New York | C3 exoenzyme-coated stents and uses thereof for treating and preventing restenosis |
EP1403519A1 (en) * | 2002-09-27 | 2004-03-31 | Novo Nordisk A/S | Membrane pump with stretchable pump membrane |
-
2002
- 2002-09-09 US US10/238,844 patent/US7429258B2/en not_active Expired - Fee Related
- 2002-10-18 AU AU2002353840A patent/AU2002353840B2/en not_active Ceased
- 2002-10-18 WO PCT/US2002/033544 patent/WO2003037403A1/en active Application Filing
- 2002-10-18 AT AT02789233T patent/ATE420680T1/en not_active IP Right Cessation
- 2002-10-18 JP JP2003539742A patent/JP2005525141A/en active Pending
- 2002-10-18 DE DE60230896T patent/DE60230896D1/en not_active Expired - Lifetime
- 2002-10-18 CA CA2464483A patent/CA2464483C/en not_active Expired - Fee Related
- 2002-10-18 EP EP02789233A patent/EP1439871B1/en not_active Expired - Lifetime
- 2002-10-21 AT AT02782208T patent/ATE386561T1/en not_active IP Right Cessation
- 2002-10-21 DE DE60225172T patent/DE60225172D1/en not_active Expired - Lifetime
- 2002-10-21 CA CA2464485A patent/CA2464485C/en not_active Expired - Fee Related
- 2002-10-21 US US10/277,724 patent/US20030083618A1/en not_active Abandoned
- 2002-10-21 JP JP2003539743A patent/JP4612304B2/en not_active Expired - Fee Related
- 2002-10-21 EP EP02782208A patent/EP1446176B1/en not_active Expired - Lifetime
- 2002-10-21 US US10/278,050 patent/US7066922B2/en not_active Expired - Lifetime
- 2002-10-21 WO PCT/US2002/033794 patent/WO2003037404A1/en active IP Right Grant
- 2002-10-21 US US10/278,049 patent/US7364568B2/en not_active Expired - Fee Related
- 2002-10-21 US US10/277,722 patent/US7645263B2/en not_active Expired - Fee Related
- 2002-10-22 WO PCT/US2002/033830 patent/WO2003037407A1/en active Application Filing
- 2002-10-22 DE DE60230795T patent/DE60230795D1/en not_active Expired - Lifetime
- 2002-10-22 EP EP02784220A patent/EP1438092A2/en not_active Withdrawn
- 2002-10-22 WO PCT/US2002/033829 patent/WO2003037406A2/en not_active Application Discontinuation
- 2002-10-22 JP JP2003539745A patent/JP2005507715A/en active Pending
- 2002-10-22 AU AU2002348009A patent/AU2002348009B9/en not_active Ceased
- 2002-10-22 CA CA2464673A patent/CA2464673C/en not_active Expired - Fee Related
- 2002-10-22 JP JP2003539744A patent/JP4610192B2/en not_active Expired - Fee Related
- 2002-10-22 EP EP02784221A patent/EP1448253B1/en not_active Expired - Lifetime
- 2002-10-22 AU AU2002353855A patent/AU2002353855B2/en not_active Ceased
- 2002-10-22 CA CA002464487A patent/CA2464487A1/en not_active Abandoned
- 2002-10-22 AT AT02784221T patent/ATE419885T1/en not_active IP Right Cessation
- 2002-10-22 EP EP02789250A patent/EP1443990A1/en not_active Ceased
- 2002-10-22 WO PCT/US2002/033823 patent/WO2003037405A1/en active Application Filing
- 2002-10-22 JP JP2003539746A patent/JP4610193B2/en not_active Expired - Fee Related
- 2002-10-22 CA CA2464670A patent/CA2464670C/en not_active Expired - Fee Related
-
2005
- 2005-10-19 JP JP2005304325A patent/JP2006081918A/en active Pending
-
2008
- 2008-01-11 US US11/972,726 patent/US7651475B2/en not_active Expired - Fee Related
- 2008-04-29 US US12/150,606 patent/US8246582B2/en not_active Expired - Fee Related
-
2009
- 2009-05-11 JP JP2009114990A patent/JP2009240790A/en active Pending
- 2009-05-11 JP JP2009114989A patent/JP2009219886A/en active Pending
- 2009-05-11 JP JP2009114991A patent/JP2009219887A/en active Pending
- 2009-05-11 JP JP2009114992A patent/JP2009219888A/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2464670A1 (en) | Transdermal transport device with suction | |
ATE433712T1 (en) | DEVICES FOR INTERSTITIAL INJECTION OF BIOLOGICAL ACTIVE SUBSTANCES INTO TISSUE | |
AU2002213168A1 (en) | Microstructures for delivering a composition cutaneously to skin | |
AU2001288774B2 (en) | Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure | |
AU2001275260A1 (en) | Method and apparatus for enhancing penetration of a puncturing member into the intradermal space | |
CA2425315A1 (en) | Apparatus and method for piercing skin with microprotrusions | |
AU2088301A (en) | Device for enhancing transdermal flux of sampled agents | |
CA2456626A1 (en) | Microstructures for delivering a composition cutaneously to skin using rotatable structures | |
CA2185024A1 (en) | Transdermal drug delivery by electroincorporation of microcarriers | |
IL141209A0 (en) | Apparatus for delivering a substance having one or more needles driven at high velocity | |
WO2001015771A3 (en) | Delivery of ultrasound to percutaneous and intrabody devices | |
ATE463207T1 (en) | DEVICES FOR THE INTERSTITIAL INJECTION OF BIOLOGICAL AGENTS INTO TISSUE | |
AU2001268963A1 (en) | Apparatus for positioning a diagnostic or therapeutic element within the body and tip electrode for use with same | |
WO1999034734A8 (en) | Biopsy instrument | |
ATE483493T1 (en) | MEDICAL DEVICE | |
WO2006073869A3 (en) | System and method for inserting a needle into a blood vessel | |
CN1281376A (en) | Device for enhancing transdermal agent flux | |
GB2184021A (en) | Laser treatment apparatus for port wine stains | |
AU2001288774A1 (en) | Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure | |
WO2005112800A3 (en) | Intraosseous infusion device | |
WO2004019777A3 (en) | Substance delivery via rotating mocroabrading surface | |
ES2143641T3 (en) | SURFACE EXPRESSION OF AN ENZYME IN GENE THERAPY BASED ON DRUGS. | |
ATE283090T1 (en) | DEVICE FOR REMOVAL OF TATTOOS WITHOUT SCARS | |
US20070208363A1 (en) | Device and Method of Minimally Invasive Tattooing and Tattoo Removal | |
US9364650B2 (en) | Method for removing pigments from a pigmented section of skin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |