CA2469396A1 - Improved breath collection apparatus - Google Patents

Improved breath collection apparatus Download PDF

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Publication number
CA2469396A1
CA2469396A1 CA002469396A CA2469396A CA2469396A1 CA 2469396 A1 CA2469396 A1 CA 2469396A1 CA 002469396 A CA002469396 A CA 002469396A CA 2469396 A CA2469396 A CA 2469396A CA 2469396 A1 CA2469396 A1 CA 2469396A1
Authority
CA
Canada
Prior art keywords
breath
portal
volatile organic
organic components
entry
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002469396A
Other languages
French (fr)
Other versions
CA2469396C (en
Inventor
Michael Phillips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2469396A1 publication Critical patent/CA2469396A1/en
Application granted granted Critical
Publication of CA2469396C publication Critical patent/CA2469396C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
    • G01N1/2214—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling by sorption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/025—Gas chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/12—Preparation by evaporation
    • G01N2030/121—Preparation by evaporation cooling; cold traps
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/12—Preparation by evaporation
    • G01N2030/126—Preparation by evaporation evaporating sample
    • G01N2030/128—Thermal desorption analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/903—Specified use of nanostructure for conversion, containment, or destruction of hazardous material

Abstract

An arrangement for the collection, concentration, and optional analysis of volatile organic components in a alveolar breath includes a condensation unit which removes water vapor from the alveolar breath.

Claims (6)

1. Arrangement for collection of volatile organic components in alveolar breath comprising a hollow container having a first end and a second end, a breath entry portal proximal to the first end, a breath exit portal proximal to the second end, and a sampling portal between the entry and the exit portals;
a condensation unit connected to the sampling portal, and a sorbent trap connected to the condensation unit.
2. Arrangement for collection of volatile organic components in alveolar breath according to claim 1 further comprising a coupler which delivers exhaled breath from a subject to the breath entry portal.
3. Arrangement according to claim 1 wherein the sampling portal is proximal to the breath entry portal and distal to the breath exit portal.
4. Arrangement according to claim 1 further comprising a thermal desorption unit connected to the absorbent trap.
5. Arrangement according to claim 4 further comprising a mobile assay unit connected to the sorbent trap.
6. A method for analyzing volatile organic components in alveolar breath comprising:
receiving a breath sample in a breath reservoir, conveying the breath sample to a condensor, removing water vapor present in the breath sample in the condensor, thereafter contacting the breath sample with a sorbent trap, and analyzing volatile organic components absorbed into the sorbent trap.
CA2469396A 2001-12-06 2002-12-05 Improved breath collection apparatus Expired - Fee Related CA2469396C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/008,642 2001-12-06
US10/008,642 US6726637B2 (en) 2001-12-06 2001-12-06 Breath collection apparatus
PCT/US2002/038571 WO2003049595A2 (en) 2001-12-06 2002-12-05 Improved breath collection apparatus

Publications (2)

Publication Number Publication Date
CA2469396A1 true CA2469396A1 (en) 2003-06-19
CA2469396C CA2469396C (en) 2012-03-06

Family

ID=21732792

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2469396A Expired - Fee Related CA2469396C (en) 2001-12-06 2002-12-05 Improved breath collection apparatus

Country Status (6)

Country Link
US (1) US6726637B2 (en)
EP (1) EP1496789B1 (en)
JP (1) JP2005512067A (en)
AU (1) AU2002362047C1 (en)
CA (1) CA2469396C (en)
WO (1) WO2003049595A2 (en)

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Also Published As

Publication number Publication date
WO2003049595A2 (en) 2003-06-19
AU2002362047B2 (en) 2007-01-04
JP2005512067A (en) 2005-04-28
AU2002362047A1 (en) 2003-06-23
EP1496789A4 (en) 2008-09-10
WO2003049595A3 (en) 2004-11-11
US20030109794A1 (en) 2003-06-12
EP1496789A2 (en) 2005-01-19
EP1496789B1 (en) 2013-01-16
CA2469396C (en) 2012-03-06
US6726637B2 (en) 2004-04-27
AU2002362047C1 (en) 2009-05-21

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