CA2490066A1 - Plugged tip delivery tube for marker placement - Google Patents
Plugged tip delivery tube for marker placement Download PDFInfo
- Publication number
- CA2490066A1 CA2490066A1 CA002490066A CA2490066A CA2490066A1 CA 2490066 A1 CA2490066 A1 CA 2490066A1 CA 002490066 A CA002490066 A CA 002490066A CA 2490066 A CA2490066 A CA 2490066A CA 2490066 A1 CA2490066 A1 CA 2490066A1
- Authority
- CA
- Canada
- Prior art keywords
- plug
- marker
- delivery device
- materials
- delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003550 marker Substances 0.000 title claims abstract 34
- 238000000034 method Methods 0.000 claims abstract 11
- 238000003384 imaging method Methods 0.000 claims abstract 9
- 230000000975 bioactive effect Effects 0.000 claims abstract 7
- 238000002604 ultrasonography Methods 0.000 claims abstract 4
- 238000002595 magnetic resonance imaging Methods 0.000 claims abstract 2
- 239000000463 material Substances 0.000 claims 29
- 239000002250 absorbent Substances 0.000 claims 3
- 230000002745 absorbent Effects 0.000 claims 3
- 230000003444 anaesthetic effect Effects 0.000 claims 3
- 230000000843 anti-fungal effect Effects 0.000 claims 3
- 230000000840 anti-viral effect Effects 0.000 claims 3
- 229940121375 antifungal agent Drugs 0.000 claims 3
- 230000003115 biocidal effect Effects 0.000 claims 3
- 230000000973 chemotherapeutic effect Effects 0.000 claims 3
- 230000002439 hemostatic effect Effects 0.000 claims 3
- 239000012857 radioactive material Substances 0.000 claims 3
- 238000001574 biopsy Methods 0.000 claims 2
- 230000003902 lesion Effects 0.000 claims 2
- 230000000717 retained effect Effects 0.000 claims 2
- 238000012285 ultrasound imaging Methods 0.000 claims 1
- 238000000429 assembly Methods 0.000 abstract 2
- 230000000712 assembly Effects 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3904—Markers, e.g. radio-opaque or breast lesions markers specially adapted for marking specified tissue
- A61B2090/3908—Soft tissue, e.g. breast tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3925—Markers, e.g. radio-opaque or breast lesions markers ultrasonic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3987—Applicators for implanting markers
Abstract
The invention provides marker delivery devices, assemblies, and methods. Assemblies embodying features of the invention include marker delivery devic es having a delivery tube with an orifice, markers, and a plug releasably disposed in the tube occluding the orifice. The plug prevents markers from passing through the orifice before the marker is to be placed at a desired location within a patient's body, prevents ingress of tissue into the bore o f the tube, and allows markers to pass out of the orifice when marker delivery is desired. Guidance of a delivery tube to a desired location within a patient's body may include the use of an imaging device, with or without the use of a guide cannula. The plug may itself serve as a marker, and may be th e sole marker. Markers may be detectable by ultrasound, X-ray, magnetic resonance imaging, and other imaging devices, and may include bioactive elements.
Claims (49)
1. An intracorporeal marker delivery device comprising:
a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the orifice;
at least one marker body which is slidably disposed within the bore; and a plug, which is releasably secured within the bore distal to the marker, which is configured to retain said at least one marker body when secured within the bore, and which allows passage of a marker body out of said orifice when released from the bore.
a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the orifice;
at least one marker body which is slidably disposed within the bore; and a plug, which is releasably secured within the bore distal to the marker, which is configured to retain said at least one marker body when secured within the bore, and which allows passage of a marker body out of said orifice when released from the bore.
2. The delivery device of claim 1, wherein said plug is formed at least in part of a marker.
3. The delivery device of claim 1, wherein said plug at least partially occludes said orifice so as to prevent ingress of tissue.
4. The delivery device of claim 1, wherein said plug occludes substantially all of said orifice.
5. The delivery device of claim 1, wherein said plug is disposed at least in part within said orifice.
6. The delivery device of claim 5, wherein at least part of said plug is configured to fit tightly within at least part of said bore so as to be releasably secured therein.
7. The delivery device of claim 6, wherein at least part of said plug is configured to press against at least part of said bore.
8. The delivery device of claim 7, wherein said plug comprises an expandable element configured to urge against said bore.
9. The delivery device of claim 8, wherein said expandable element is selected from the group of elements consisting of a spring, a coil, a clip, a loop, an arch, and a resilient core.
10. The delivery device of claim 9, wherein said expandable element includes a radiopaque element.
11. The delivery device of claim 1, wherein said delivery tube has a tube wall has at least one retaining feature configured to releasably retain a plug.
12. The delivery device of claim 11, wherein a delivery tube wall retaining feature includes a protuberance.
13. The delivery device of claim 11, wherein a delivery tube wall retaining feature includes a recess.
14. The delivery device of claim 11, wherein a delivery tube wall retaining feature is selected from the group consisting of notches, holes, slots, tabs, and ridges.
15. The delivery device of claim 1, wherein said plug is formed of a bioresorbable material.
16. The delivery device of claim 2, wherein said plug comprises a permanent marker.
17. The delivery device of claim 2, wherein said plug is detectable with ultrasound.
18. The delivery device of claim 2, wherein said plug is formed at least in part of a radiopaque material.
19. The delivery device of claim 2, wherein said plug has at least one bioactive element.
20. The delivery device of claim 19, wherein at least one bioactive element is selected from the group consisting of hemostatic materials, anesthetic materials, absorbent materials, antibiotic materials, antifungal materials, antiviral materials, chemotherapeutic materials, radioactive materials, and other pharmaceutical materials.
21. The delivery device of claim 1, wherein a plurality of markers are disposed within the bore proximal to the plug.
22. The delivery device of claim 21, wherein a movable plunger is slidably disposed within the bore and is configured to expel markers through said orifice.
23. A plug configured to be releasably retained within a bore of a delivery device effective to retain a marker therein and having an inclined end surface.
24. The plug of claim 23, wherein said plug is formed of a bioresorbable material.
25. The plug of claim 23, wherein said plug is a permanent marker.
26. The plug of claim 23, wherein said plug is formed of an ultrasound detectable material.
27. The plug of claim 23, wherein said plug is formed of a radiopaque material.
28. The plug of claim 23, wherein said plug has at least one bioactive element.
29. The plug of claim 28, wherein at least one bioactive element is selected from the group consisting of hemostatic materials, anesthetic materials, absorbent materials, antibiotic materials, antifungal materials, antiviral materials, chemotherapeutic materials, radioactive materials, and other pharmaceutical materials.
30. A marker delivery system comprising a delivery tube having a distal tip with an orifice therein, an inner bore extending therein to the orifice in the distal tip, a movable plunger disposed within said bore, and a plug releasably secured within the orifice within the distal tip.
31. The marker delivery device of claim 30, wherein a distal portion of said delivery tube wall has at least one retaining feature configured to releasably retain the plug.
32. The marker delivery device of claim 31, wherein said retaining feature is selected from the group consisting of notches, holes, slots, tabs, and ridges.
33. A method of delivering a marker to a desired location within a body of a patient, comprising inserting into a patient a marker delivery device comprising a delivery cannula with a distal tip and having a bore, an orifice disposed at said distal tip, a plug releasably retained within the bore, and at least one marker slidably disposed within the bore proximal to the plug;
advancing a plunger within the bore to press on a marker therein against the plug thereby; and expelling the plug and a marker from said orifice into said desired location.
advancing a plunger within the bore to press on a marker therein against the plug thereby; and expelling the plug and a marker from said orifice into said desired location.
34. The method of claim 33, wherein inserting comprises guiding said delivery cannula within said body of said patient with the aid of a guide cannula.
35. The method of claim 33, wherein the delivery cannula is guided within the patient with the aid of an imaging device.
36. The method of claim 35, wherein said imaging device is an ultrasound imaging device.
37. The method of claim 35, wherein said imaging device is an x-ray imaging device.
38. The method of claim 35, wherein said imaging device is a magnetic resonance imaging device.
39. The method of claim 33, wherein the desired location is a lesion site within said body of said patient.
40. The method of claim 33, wherein the desired location is a biopsy cavity within said body of said patient.
41. The method of claim 39, wherein inserting further comprises guiding said delivery cannula adjacent said lesion site with the aid of an imaging device.
42. The method of claim 40, wherein inserting further comprises guiding said delivery cannula adjacent said biopsy cavity with the aid of an imaging device.
43. An intracorporeal marker delivery device comprising:
a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the orifice; and a plug comprising a marker body which is releasably secured within the bore and disposed so as to at least partially occlude said discharge orifice.
a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the orifice; and a plug comprising a marker body which is releasably secured within the bore and disposed so as to at least partially occlude said discharge orifice.
44. The intracorporeal marker delivery device of claim 43, wherein said plug comprises a bioresorbable marker.
45. The intracorporeal marker delivery device of claim 43, wherein said plug comprises a permanent marker.
46. The intracorporeal marker delivery device of claim 43, wherein said plug comprises a radiopaque element.
47. The intracorporeal marker delivery device of claim 43, wherein said plug is detectable with ultrasound.
48. The intracorporeal marker delivery device of claim 43, wherein said plug comprises a bioactive element.
49. The intracorporeal marker delivery device of claim 48, wherein said plug comprises a bioactive element selected from the group consisting of hemostatic materials, anesthetic materials, absorbent materials, antibiotic materials, antifungal materials, antiviral materials, chemotherapeutic materials, radioactive materials, and other pharmaceutical materials.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/174,401 US7651505B2 (en) | 2002-06-17 | 2002-06-17 | Plugged tip delivery for marker placement |
US10/174,401 | 2002-06-17 | ||
PCT/US2003/018728 WO2003105940A2 (en) | 2002-06-17 | 2003-06-11 | Plugged tip delivery tube for marker placement |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2490066A1 true CA2490066A1 (en) | 2003-12-24 |
CA2490066C CA2490066C (en) | 2011-07-19 |
Family
ID=29733572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2490066A Expired - Lifetime CA2490066C (en) | 2002-06-17 | 2003-06-11 | Plugged tip delivery tube for marker placement |
Country Status (6)
Country | Link |
---|---|
US (3) | US7651505B2 (en) |
EP (1) | EP1513581B1 (en) |
AU (1) | AU2003245489A1 (en) |
CA (1) | CA2490066C (en) |
ES (1) | ES2429419T3 (en) |
WO (1) | WO2003105940A2 (en) |
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2002
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- 2003-06-11 ES ES03739124T patent/ES2429419T3/en not_active Expired - Lifetime
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US8177792B2 (en) | 2012-05-15 |
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WO2003105940A3 (en) | 2004-04-22 |
US7651505B2 (en) | 2010-01-26 |
US8784433B2 (en) | 2014-07-22 |
US20120215230A1 (en) | 2012-08-23 |
CA2490066C (en) | 2011-07-19 |
AU2003245489A1 (en) | 2003-12-31 |
EP1513581B1 (en) | 2013-05-01 |
EP1513581A2 (en) | 2005-03-16 |
US20100094169A1 (en) | 2010-04-15 |
US20030233101A1 (en) | 2003-12-18 |
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