CA2568420A1 - Electrosurgical forceps with energy based tissue division - Google Patents
Electrosurgical forceps with energy based tissue division Download PDFInfo
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- CA2568420A1 CA2568420A1 CA002568420A CA2568420A CA2568420A1 CA 2568420 A1 CA2568420 A1 CA 2568420A1 CA 002568420 A CA002568420 A CA 002568420A CA 2568420 A CA2568420 A CA 2568420A CA 2568420 A1 CA2568420 A1 CA 2568420A1
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- jaw members
- tissue
- energy
- cutting element
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1442—Probes having pivoting end effectors, e.g. forceps
- A61B18/1445—Probes having pivoting end effectors, e.g. forceps at the distal end of a shaft, e.g. forceps or scissors at the end of a rigid rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1442—Probes having pivoting end effectors, e.g. forceps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00184—Moving parts
- A61B2018/0019—Moving parts vibrating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00404—Blood vessels other than those in or around the heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00601—Cutting
Abstract
An electrosurgical bipolar forceps for sealing and dividing tissue is disclosed. The forceps includes one or more shaft members having an end effector assembly disposed at a distal end thereof. The end effector assembly includes two jaw members movable from a first position to a second position wherein the jaw members cooperate to grasp tissue therebetween. Each of the jaw members includes an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween. The forceps also include an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members. The energy-based cutting element is moveable from a first configuration when said jaw members are in the first position to a second configuration wherein the energy-based cutting element is disposed at an angle between the jaw members.
Description
ELECTROSURGICAL FORCEPS WITH ENERGY BASED TISSUE DIVISION
BACKGROUND
Technical Field The present disclosure relates to an electrosurgical instrument and method for performing electrosurgical procedures. More particularly, the present disclosure relates to an open or endoscopic bipolar electrosurgical forceps including opposing jaw members which include an energy-based cutting element (e.g., cutting electrode) for energy based tissue division.
Background of Related Art A forceps is a pliers-like instrument which relies on mechanical action between its jaws to grasp, clamp and constrict vessels or tissue. So-called "open forceps" are commonly used in open surgical procedures whereas "endoscopic forceps" or "laparoscopic forceps" are, as the name implies, used for less invasive endoscopic surgical procedures.
Electrosurgical forceps (open or endoscopic) utilize mechanical clamping action and electrical energy to effect hemostasis on the clamped tissue. The forceps include electrosurgical conductive plates which apply the electrosurgical energy to the clainped tissue. By controlling the intensity, frequency and duration of the electrosurgical energy applied through the conductive plates to the tissue, the surgeon can coagulate, cauterize and/or seal tissue.
Tissue or vessel sealing is a process of liquefying the collagen, elastin and ground substances in the tissue so that they reform into a fused mass with significantly-reduced demarcation between the opposing tissue structures. Cauterization involves the use of heat to destroy tissue and coagulation is a process of desiccating tissue wherein the tissue cells are ruptured and dried.
Since tissue sealing procedures involve more than simply cauterizing tissue, to create an effective seal the procedures involve precise control of a variety of factors.
In order to affect a proper seal in vessels or tissue, it has been determined that two predominant mechanical parameters must be accurately controlled: the pressure applied to the tissue;
and the gap distance between the electrodes (i.e., distance between opposing jaw members when closed about tissue).
Many of the instruments of the past include blade members or shearing members which simply cut tissue in a mechanical and/or electromechanical manner. Other instruments generally rely on clarnping pressure alone to procure proper sealing thickness and are often not designed to take into account gap tolerances and/or parallelism and flatness requirements which are parameters which, if properly controlled, can assure a consistent and effective tissue seal.
In addition, conventional or known tissue sealing reciprocating instruments have cutting mechanisms which are primarily designed to mechanically divide tissue (i.e., knife blade) and do not divide tissue in an electrosurgical fashion.
Thus, a need exists to develop an electrosurgical instrument which effectively and consistently seals, coagulates or cauterizes tissue and which is selectively configurable to cut tissue in an electrosurgical fashion.
SUMMARY
The present disclosure relates to a vessel or tissue sealing and dividing instrument which is designed to manipulate, grasp and seal tissue utilizing jaw members which are configured to close about tissue to produce a highly effective tissue seal.
The instrument includes a pair of jaw members configured for sealing tissue and an energy-based cutting element attached at two or more pivot points to the jaw members. When the jaw members are open, the cutting element is deployed and the instrument can be used to divide tissue. When the jaw members are closed about tissue and the instrument can be used to seal tissue.
One embodiment according to the present disclosure relates to an electrosurgical bipolar forceps for sealing and dividing tissue. An electrosurgical bipolar forceps for sealing and dividing tissue is disclosed. The forceps includes one or more shaft members having an end effector assembly disposed at a distal end thereof. The end effector assembly includes two jaw members movable from a first position to a second position wherein the jaw members cooperate to grasp tissue therebetween. Each of the jaw members includes an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween. The forceps also include an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members. The energy-based cutting element is moveable from a first configuration when said jaw members are in the first position to a second configuration wherein the energy-based cutting element is disposed at an angle between the jaw members.
Another embodiment according to the present disclosure relates to a method.
The method includes the steps of providing an electrosurgical bipolar forceps. The forceps includes two jaw members movable from a first position to a second position wherein the jaw members cooperate to grasp tissue therebetween. Each of the jaw members includes an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween. The forceps also include an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members. The energy-based cutting element is moveable from a first configuration when said jaw members are in the first position to a second configuration wherein the energy-based cutting element is disposed at an angle between the jaw members. The method also includes the steps of positioning the jaw members in the first position to deploy the energy-based cutting element, supplying electrosurgical energy to the energy-based cutting element, and moving electrosurgical bipolar forceps to position the energy-based cutting element in operative proximity to tissue thereby cutting tissue.
A further embodiment according to the present disclosure relates to another method. The method includes the steps of providing an electrosurgical bipolar forceps. The forceps includes two jaw members movable from a first position to a second position wherein the jaw members cooperate to grasp tissue therebetween. Each of the jaw members includes an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween. The forceps also include an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members. The energy-based cutting element is moveable from a first configuration when said jaw members are in the first position to a second configuration wherein the energy-based cutting element is disposed at an angle between the jaw members. The method also includes the steps of positioning the jaw members into the subsequent position wherein the jaw members cooperate to grasp tissue therebetween and communicating electrosurgical energy through tissue held therebetween thereby sealing tissue.
BRIEF DESCRIPTION OF THE DRAWINGS
Various embodiments of the present disclosure are described herein with reference to the drawings wherein:
Fig. 1 is a perspective view of an endoscopic bipolar forceps having a cutting element according to the present disclosure;
Fig. 2 is a side, partial internal view of an endoscopic forceps showing a cutting electrode in a deployed configuration according to the present disclosure;
Fig. 3A is a front view of another end effector assembly according to the present disclosure;
Fig. 3B is a front view of another end effector assembly according to the present disclosure;
Fig. 4 is a rear, perspective view of the end effector of Fig. 3A shown with tissue grasped therein; and Fig. 5 is a perspective view of an open bipolar forceps having a cutting element according to the present disclosure.
DETAILED DESCRIPTION
Particular embodiments of the present disclosure will be described hereinbelow with reference to the accompanying drawings. In the following description, well-known functions or constructions are not described in detail to avoid obscuring the present disclosure in unnecessary detail.
Fig. 1 shows an endoscopic vessel sealing bipolar forceps 10. Those skilled in the art will understand that the invention according to the present disclosure may be adapted for use with either an endoscopic instrument or an open instrument. It should also be appreciated that different electrical and mechanical connections and other considerations apply to each particular type of instrument, however, the novel aspects with respect to the energy-based cutting element for energy based tissue division are generally consistent with respect to both the open or endoscopic designs. Moreover and as described herein, the various figures show vessel sealin instruments for use with energy-based cutting element, however other instruments may be configured to use the same or similar cutting element, e.g., cauterizing instruments, coagulators, etc.
In the drawings and in the description which follows, the term "proximal", refers to the end of the forceps 10 which is closer to the user, while the term "distal"
refers to the end of the forceps which is further from the user.
Figs. 1-4 show the forceps 10 which is configured to support an effector assembly 100.
More particularly, forceps 10 generally includes a housing 20, a handle assembly 30, a rotating assembly 80, and a trigger assembly 70 which mutually cooperate with the end effector assembly 100 to grasp, seal and, if required, divide tissue. The forceps 10 also includes a shaft 12 which has a distal end 14 which mechanically engages the end effector assembly 100 and a proximal end 16 which mechanically engages the housing 20 proximate the rotating assembly 80.
The forceps 10 also includes a plug (not shown) which connects the forceps 10 to a source of electrosurgical energy, e.g., an electrosurgical generator 500, via an electrical cable 310. Handle assembly 30 includes a fixed handle 50 and a movable handle 40.
Handle 40 moves relative to the fixed handle 50 to actuate the end effector assembly 100 and enable a user to grasp and manipulate tissue 400 as shown in Fig. 2.
The end effector assembly 100 includes a pair of opposing jaw members 110 and each having an electrically conductive sealing plate 112 and 122, respectively, attached thereto for conducting electrosurgical energy through tissue 400 held therebetween.
More particularly, the jaw members 110 and 120 move in response to movement of the handle 40 from an open position to a closed position. In open position the sealing plates 112 and 122 are disposed in spaced relation relative to one another. In a clamping or closed position the sealing plates 112 and 122 cooperate to grasp tissue and apply electrosurgical energy thereto.
The jaw members 110 and 120 are activated using a drive assembly (not shown) enclosed within the housing 20. The drive assembly cooperates with the movable handle 40 to impart movement of the jaw members 110 and 120 from the open position to the clamping or closed position. Examples of a handle assemblies are shown and described in commonly-owned U.S.
Application Serial No. 10/389,894 entitled "VESSEL SEALER AND DIVIDER AND
METHOD MANUFACTURING SAME" and commonly owned U.S. Application Serial No.
10/460,926 entitled "VESSEL SEALER AND DIVIDER FOR USE WITH SMALL TROCARS
AND CANNULAS" which are both hereby incorporated by reference herein in their entirety.
In addition, the handle assembly 30 of this particular disclosure includes a four-bar mechanical linkage which provides a unique mechanical advantage when sealing tissue between the jaw members 110 and 120. For example, once the desired position for the sealing site is determined and the jaw members 110 and 120 are properly positioned, handle 40 may be compressed fully to lock the electrically conductive sealing plates 112 and 122 in a closed position against the tissue. The details relating to the inter-cooperative relationships of the inner-working components of forceps 10 are disclosed in the above-cited commonly-owned U.S. Patent Application No. 10/369,894. Another example of an endoscopic handle assembly which discloses an off-axis, lever-like handle assembly, is disclosed in the above-cited U.S. Patent Application Serial No. 10/460,926.
The forceps 10 also includes a rotating assembly 80 mechanically associated with the shaft 12 and the drive assembly (not shown). Movement of the rotating assembly 80 imparts similar rotational movement to the shaft 12 which, in turn, rotates the end effector assembly 100. Various features along with various electrical configurations for the transference of electrosurgical energy through the handle assembly 20 and the rotating assembly 80 are described in more detail in the above-mentioned commonly-owned U.S. Patent Application Nos. 10/369,894 and 10/460,926.
As best seen with respect to Figs. 1-2, the end effector assembly 100 attaches to the distal end 14 of shaft 12. The jaw members 110 and 120 are preferably pivotable about a pivot 160 from the open to closed positions upon relative reciprocation, i.e., longitudinal movement, of the drive assembly (not shown). Again, mechanical and cooperative relationships with respect to the various moving elements of the end effector assembly 100 are further described by example with respect to the above-mentioned commonly-owned U.S. Patent Application Nos. 10/369,894 and 10/460,926.
It is envisioned that the forceps 10 may be designed such that it is fully or partially disposable depending upon a particular purpose or to achieve a particular result. For example, end effector assembly 100 may be selectively and releasably engageable with the distal end 14 of the shaft 12 and/or the proximal end 16 of the shaft 12 may be selectively and releasably engageable with the housing 20 and handle assembly 30. In either of these two instances, the forceps 10 may be either partially disposable or reposable, such as where a new or different end effector assembly 100 or end effector assembly 100 and shaft 12 are used to selectively replace the old end effector assembly 100 as needed.
Since the forceps 10 applies energy through electrodes, each of the jaw members 110 and 120 includes a pair of electrically conductive surfaces 112, 122 respectively, disposed on an inner-facing surface thereof. Thus, once the jaw members 110 and 120 are fully compressed about the tissue 400, the forceps 10 is now ready for selective application of electrosurgical energy as shown in Fig. 4. In order to seal tissue, the tissue grasped by the jaw members 110, 120 under a specified closure pressure from about 3 kg/cm2 to about 16 kg/cm2 and the jaw members 110, 120 are designed to maintain a gap from about 0.001 inches to about 0.006 inches.
At that point, the electrically conductive surfaces 112 and 122 cooperate to seal tissue 400 held therebetween upon the application of electrosurgical energy. Jaw members 110 and 120 also include insulators 116 and 126 which together with the outer, non-conductive plates of the jaw members 110 and 120 are configured to limit and/or reduce many of the known undesirable effects related to tissue sealing, e.g., flashover, thermal spread and stray current dissipation.
With reference to Figs. 2-3, an energy-based cutting element or center electrode 130 is deployable between electrically conductive surfaces 112, 122, respectively.
The cutting element 130 may be an electrode configured to transmit electrosurgical energy, an ultrasonic probe configured to transmit ultrasonic energy or a thermal blade capable of transmitting heat to the tissue.
The cutting element 130 is attached to the jaw members 110 and 120 at two pivot points 131 and 132 respectively. The pivot points 131, 132 may include attachment mechanisms or mechanical interfaces 137, 139 (e.g., pins, shafts, etc.) which attach the cutting element 130 to the jaw members 110, 120 allowing the cutting element 130 to rotate freely thereabout (e.g., pass through holes). The pivot points 131, 132 may also include grooves or guides 117, 127 within the jaw members 110, 120 which allow the ends of the cutting element 130 to move freely during transitioning between open and close positions of the jaw members 110, 120.
It is envisioned that the cutting element 130 can be shaped in a variety of geometrical configurations to provide an optimal cutting surface. For instance, the cutting element 130 may have a circular, rectangular, triangular horizontal cross section.
The pivot points 131, 132 are positioned at opposite ends of jaw members 110 and 120, respectively. More specifically, pivot point 131 is positioned at a distal end 116 of the jaw member 110 and pivot point 132 is positioned at a proximal end of the jaw member 120. The pivots 131, 132 move within groves on guides 117, 127 in jaw members 110, 120 respectively.
This configuration allows the cutting element 130 to be automatically deployed when the jaw members 110, 120 are in open position so that the cutting element 130 intersects the center plane "C." It is envisioned that the pivot points 131, 132 may be oriented in a plurality of ways which permit the cutting element 130 to be deployed at various angles "a" when the jaw members 110, 120 are open. For instance, the pivot point 131 may be disposed more towards the proximal end of jaw member 110 to increase the cutting angle the pivot point 132 may be disposed more towards the distal end of jaw member 120 depending upon a particular purpose.
The cutting angle may also be dependent in the relative opening of the jaw members 110, 120, i.e., the relative distance between the jaw members 110, 120 when opened.
As shown in Fig. 3A, the electrically conductive surfaces 112, 122 may include electrically conductive plates 140, 142, 144, 146. This permits the cutting element 130 to be attached to the jaw members 110, 120 in an unimpeded fashion, i.e., without contacting the conductive surfaces 112, 122. It is envisioned that the electrically conductive surfaces 112, 122 may include any number of electrically conductive plates, such as for instance, a single electrically conductive plate 148, 150 disposed on each jaw member 110, 120, as shown in Fig.
3B, or eight plates (not shown), etc. The single electrically conductive plate 148 may be shaped in a number of forms, such as a "U" shape, a "H" shape. It is also envisioned that the electrically conductive plate 148 may be oriented in a plurality of ways. In addition, the single conductive plate 148 may be shaped to substantially match the surface of the jaw members 110, 120 with an opening for the pivot points 131, 132.
The ability of the cutting element 130 to automatically fold and raise as the jaw members 110, 120 are opened and closed respectively, allows the forceps 10 to have two modes of operation: a sealing mode and a cutting mode. During sealing mode, the jaw members 110 and 120 are clamped down in direction F as shown in Fig. 4 around tissue. The cutting element 130 folds down and the electrically conductive plates 140, 142, 144, 146 are energized thereby sealing tissue. Clamping of the jaw members 110, 120 is accomplished by moving the handle 40 relative to the fixed handle 50 to actuate the end effector assembly 100. The electrically conductive plates 140, 142, 144, 146 may be selectively energized once the jaw members 110, 120 are closed about tissue. The center electrode 130 in its folding orientation may be energized when the jaw members are closed to allow the user to selectively ct tissue after the seal has been formed. Alternatively, the center electrode or cutting element 130 may be energized when the jaw members are closed about tissue without prior sealing. It is envisioned that an alarm (not shown) may be included in this instance to warn the user that the tissue has not been treated prior to separation.
During an open cutting mode the jaw members 110 and 120 are open such that the cutting element 130 automatically deploys therebetween. As shown in Figs. 1-4, forceps 10 also includes a trigger 70 which activates the generator 500 to supply electrosurgical energy or other types of energy depending on the type of the cutting element 130 used (e.g., ultrasonic, heat, etc.). The forceps 10 may be manually pushed toward and into tissue 400 as shown in Fig. 2 while the cutting element 130 is energized, thereby dividing the tissue along the longitudinal axis of the forceps 10.
From the foregoing and with reference to the various figure drawings, those skilled in the art will appreciate that certain modifications can also be made to the present disclosure without departing from the scope of the same. For example and as mentioned above, it is contemplated that any of the various jaw arrangements and cutting elements disclosed herein may be employed on an open forceps such as the open forceps 700 shown in Fig. 5. The forceps 700 includes an end effector assembly 600 which is attached to the distal ends 516a and 516b of shafts 512a and 512b, respectively. The end effector assembly 600 includes pair of opposing jaw members 610 and 620 which are pivotally connected about a pivot pin 665 and which are movable relative to one another to grasp vessels and/or tissue. Each of the opposing jaw members 610, 620 include electrically conductive surfaces 112, 122 and cutting element 130 disposed therebetween. When in an open configuration, the cutting element 130 deployed and the open forceps 700 may be used for dividing tissue when the cutting element 130 is selectively energized similar to the endoscopic forceps 10 described above. The open forceps 700 may also be used for clamping tissue for sealing, coagulation or cauterization without energizing the cutting element 130.
Each shaft 512a and 512b includes a handle 515 and 517, respectively, disposed at the proximal end 514a and 514b thereof which each define a finger hole 515a and 517a, respectively, therethrough for receiving a finger of the user. Finger holes 515a and 517a facilitate movement of the shafts 512a and 512b relative to one another which, in turn, pivot the jaw members 610 and 620 from an open position wherein the jaw members 610 and 620 are disposed in spaced relation relative to one another to a clamping or closed position wherein the jaw members 610 and 620 cooperate to grasp tissue or vessels therebetween.
Further details relating to one particular open forceps are disclosed in commonly-owned U.S.
Application Serial No. 10/962,116 filed October 8, 2004 entitled "OPEN VESSEL SEALING
INSTRUMENT WITH CUTTING MECHANISM AND DISTAL LOCKOUT", the entire contentsof which being incorporated by reference herein.
While several embodiments of the disclosure have been shown in the drawings and/or discussed herein, it is not intended that the disclosure be limited thereto, as it is intended that the disclosure be as broad in scope as the art will allow and that the specification be read likewise. Therefore, the above description should not be construed as limiting, but merely as exemplifications of particular embodiments. Those skilled in the art will envision other modifications within the scope and spirit of the claims appended hereto.
BACKGROUND
Technical Field The present disclosure relates to an electrosurgical instrument and method for performing electrosurgical procedures. More particularly, the present disclosure relates to an open or endoscopic bipolar electrosurgical forceps including opposing jaw members which include an energy-based cutting element (e.g., cutting electrode) for energy based tissue division.
Background of Related Art A forceps is a pliers-like instrument which relies on mechanical action between its jaws to grasp, clamp and constrict vessels or tissue. So-called "open forceps" are commonly used in open surgical procedures whereas "endoscopic forceps" or "laparoscopic forceps" are, as the name implies, used for less invasive endoscopic surgical procedures.
Electrosurgical forceps (open or endoscopic) utilize mechanical clamping action and electrical energy to effect hemostasis on the clamped tissue. The forceps include electrosurgical conductive plates which apply the electrosurgical energy to the clainped tissue. By controlling the intensity, frequency and duration of the electrosurgical energy applied through the conductive plates to the tissue, the surgeon can coagulate, cauterize and/or seal tissue.
Tissue or vessel sealing is a process of liquefying the collagen, elastin and ground substances in the tissue so that they reform into a fused mass with significantly-reduced demarcation between the opposing tissue structures. Cauterization involves the use of heat to destroy tissue and coagulation is a process of desiccating tissue wherein the tissue cells are ruptured and dried.
Since tissue sealing procedures involve more than simply cauterizing tissue, to create an effective seal the procedures involve precise control of a variety of factors.
In order to affect a proper seal in vessels or tissue, it has been determined that two predominant mechanical parameters must be accurately controlled: the pressure applied to the tissue;
and the gap distance between the electrodes (i.e., distance between opposing jaw members when closed about tissue).
Many of the instruments of the past include blade members or shearing members which simply cut tissue in a mechanical and/or electromechanical manner. Other instruments generally rely on clarnping pressure alone to procure proper sealing thickness and are often not designed to take into account gap tolerances and/or parallelism and flatness requirements which are parameters which, if properly controlled, can assure a consistent and effective tissue seal.
In addition, conventional or known tissue sealing reciprocating instruments have cutting mechanisms which are primarily designed to mechanically divide tissue (i.e., knife blade) and do not divide tissue in an electrosurgical fashion.
Thus, a need exists to develop an electrosurgical instrument which effectively and consistently seals, coagulates or cauterizes tissue and which is selectively configurable to cut tissue in an electrosurgical fashion.
SUMMARY
The present disclosure relates to a vessel or tissue sealing and dividing instrument which is designed to manipulate, grasp and seal tissue utilizing jaw members which are configured to close about tissue to produce a highly effective tissue seal.
The instrument includes a pair of jaw members configured for sealing tissue and an energy-based cutting element attached at two or more pivot points to the jaw members. When the jaw members are open, the cutting element is deployed and the instrument can be used to divide tissue. When the jaw members are closed about tissue and the instrument can be used to seal tissue.
One embodiment according to the present disclosure relates to an electrosurgical bipolar forceps for sealing and dividing tissue. An electrosurgical bipolar forceps for sealing and dividing tissue is disclosed. The forceps includes one or more shaft members having an end effector assembly disposed at a distal end thereof. The end effector assembly includes two jaw members movable from a first position to a second position wherein the jaw members cooperate to grasp tissue therebetween. Each of the jaw members includes an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween. The forceps also include an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members. The energy-based cutting element is moveable from a first configuration when said jaw members are in the first position to a second configuration wherein the energy-based cutting element is disposed at an angle between the jaw members.
Another embodiment according to the present disclosure relates to a method.
The method includes the steps of providing an electrosurgical bipolar forceps. The forceps includes two jaw members movable from a first position to a second position wherein the jaw members cooperate to grasp tissue therebetween. Each of the jaw members includes an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween. The forceps also include an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members. The energy-based cutting element is moveable from a first configuration when said jaw members are in the first position to a second configuration wherein the energy-based cutting element is disposed at an angle between the jaw members. The method also includes the steps of positioning the jaw members in the first position to deploy the energy-based cutting element, supplying electrosurgical energy to the energy-based cutting element, and moving electrosurgical bipolar forceps to position the energy-based cutting element in operative proximity to tissue thereby cutting tissue.
A further embodiment according to the present disclosure relates to another method. The method includes the steps of providing an electrosurgical bipolar forceps. The forceps includes two jaw members movable from a first position to a second position wherein the jaw members cooperate to grasp tissue therebetween. Each of the jaw members includes an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween. The forceps also include an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members. The energy-based cutting element is moveable from a first configuration when said jaw members are in the first position to a second configuration wherein the energy-based cutting element is disposed at an angle between the jaw members. The method also includes the steps of positioning the jaw members into the subsequent position wherein the jaw members cooperate to grasp tissue therebetween and communicating electrosurgical energy through tissue held therebetween thereby sealing tissue.
BRIEF DESCRIPTION OF THE DRAWINGS
Various embodiments of the present disclosure are described herein with reference to the drawings wherein:
Fig. 1 is a perspective view of an endoscopic bipolar forceps having a cutting element according to the present disclosure;
Fig. 2 is a side, partial internal view of an endoscopic forceps showing a cutting electrode in a deployed configuration according to the present disclosure;
Fig. 3A is a front view of another end effector assembly according to the present disclosure;
Fig. 3B is a front view of another end effector assembly according to the present disclosure;
Fig. 4 is a rear, perspective view of the end effector of Fig. 3A shown with tissue grasped therein; and Fig. 5 is a perspective view of an open bipolar forceps having a cutting element according to the present disclosure.
DETAILED DESCRIPTION
Particular embodiments of the present disclosure will be described hereinbelow with reference to the accompanying drawings. In the following description, well-known functions or constructions are not described in detail to avoid obscuring the present disclosure in unnecessary detail.
Fig. 1 shows an endoscopic vessel sealing bipolar forceps 10. Those skilled in the art will understand that the invention according to the present disclosure may be adapted for use with either an endoscopic instrument or an open instrument. It should also be appreciated that different electrical and mechanical connections and other considerations apply to each particular type of instrument, however, the novel aspects with respect to the energy-based cutting element for energy based tissue division are generally consistent with respect to both the open or endoscopic designs. Moreover and as described herein, the various figures show vessel sealin instruments for use with energy-based cutting element, however other instruments may be configured to use the same or similar cutting element, e.g., cauterizing instruments, coagulators, etc.
In the drawings and in the description which follows, the term "proximal", refers to the end of the forceps 10 which is closer to the user, while the term "distal"
refers to the end of the forceps which is further from the user.
Figs. 1-4 show the forceps 10 which is configured to support an effector assembly 100.
More particularly, forceps 10 generally includes a housing 20, a handle assembly 30, a rotating assembly 80, and a trigger assembly 70 which mutually cooperate with the end effector assembly 100 to grasp, seal and, if required, divide tissue. The forceps 10 also includes a shaft 12 which has a distal end 14 which mechanically engages the end effector assembly 100 and a proximal end 16 which mechanically engages the housing 20 proximate the rotating assembly 80.
The forceps 10 also includes a plug (not shown) which connects the forceps 10 to a source of electrosurgical energy, e.g., an electrosurgical generator 500, via an electrical cable 310. Handle assembly 30 includes a fixed handle 50 and a movable handle 40.
Handle 40 moves relative to the fixed handle 50 to actuate the end effector assembly 100 and enable a user to grasp and manipulate tissue 400 as shown in Fig. 2.
The end effector assembly 100 includes a pair of opposing jaw members 110 and each having an electrically conductive sealing plate 112 and 122, respectively, attached thereto for conducting electrosurgical energy through tissue 400 held therebetween.
More particularly, the jaw members 110 and 120 move in response to movement of the handle 40 from an open position to a closed position. In open position the sealing plates 112 and 122 are disposed in spaced relation relative to one another. In a clamping or closed position the sealing plates 112 and 122 cooperate to grasp tissue and apply electrosurgical energy thereto.
The jaw members 110 and 120 are activated using a drive assembly (not shown) enclosed within the housing 20. The drive assembly cooperates with the movable handle 40 to impart movement of the jaw members 110 and 120 from the open position to the clamping or closed position. Examples of a handle assemblies are shown and described in commonly-owned U.S.
Application Serial No. 10/389,894 entitled "VESSEL SEALER AND DIVIDER AND
METHOD MANUFACTURING SAME" and commonly owned U.S. Application Serial No.
10/460,926 entitled "VESSEL SEALER AND DIVIDER FOR USE WITH SMALL TROCARS
AND CANNULAS" which are both hereby incorporated by reference herein in their entirety.
In addition, the handle assembly 30 of this particular disclosure includes a four-bar mechanical linkage which provides a unique mechanical advantage when sealing tissue between the jaw members 110 and 120. For example, once the desired position for the sealing site is determined and the jaw members 110 and 120 are properly positioned, handle 40 may be compressed fully to lock the electrically conductive sealing plates 112 and 122 in a closed position against the tissue. The details relating to the inter-cooperative relationships of the inner-working components of forceps 10 are disclosed in the above-cited commonly-owned U.S. Patent Application No. 10/369,894. Another example of an endoscopic handle assembly which discloses an off-axis, lever-like handle assembly, is disclosed in the above-cited U.S. Patent Application Serial No. 10/460,926.
The forceps 10 also includes a rotating assembly 80 mechanically associated with the shaft 12 and the drive assembly (not shown). Movement of the rotating assembly 80 imparts similar rotational movement to the shaft 12 which, in turn, rotates the end effector assembly 100. Various features along with various electrical configurations for the transference of electrosurgical energy through the handle assembly 20 and the rotating assembly 80 are described in more detail in the above-mentioned commonly-owned U.S. Patent Application Nos. 10/369,894 and 10/460,926.
As best seen with respect to Figs. 1-2, the end effector assembly 100 attaches to the distal end 14 of shaft 12. The jaw members 110 and 120 are preferably pivotable about a pivot 160 from the open to closed positions upon relative reciprocation, i.e., longitudinal movement, of the drive assembly (not shown). Again, mechanical and cooperative relationships with respect to the various moving elements of the end effector assembly 100 are further described by example with respect to the above-mentioned commonly-owned U.S. Patent Application Nos. 10/369,894 and 10/460,926.
It is envisioned that the forceps 10 may be designed such that it is fully or partially disposable depending upon a particular purpose or to achieve a particular result. For example, end effector assembly 100 may be selectively and releasably engageable with the distal end 14 of the shaft 12 and/or the proximal end 16 of the shaft 12 may be selectively and releasably engageable with the housing 20 and handle assembly 30. In either of these two instances, the forceps 10 may be either partially disposable or reposable, such as where a new or different end effector assembly 100 or end effector assembly 100 and shaft 12 are used to selectively replace the old end effector assembly 100 as needed.
Since the forceps 10 applies energy through electrodes, each of the jaw members 110 and 120 includes a pair of electrically conductive surfaces 112, 122 respectively, disposed on an inner-facing surface thereof. Thus, once the jaw members 110 and 120 are fully compressed about the tissue 400, the forceps 10 is now ready for selective application of electrosurgical energy as shown in Fig. 4. In order to seal tissue, the tissue grasped by the jaw members 110, 120 under a specified closure pressure from about 3 kg/cm2 to about 16 kg/cm2 and the jaw members 110, 120 are designed to maintain a gap from about 0.001 inches to about 0.006 inches.
At that point, the electrically conductive surfaces 112 and 122 cooperate to seal tissue 400 held therebetween upon the application of electrosurgical energy. Jaw members 110 and 120 also include insulators 116 and 126 which together with the outer, non-conductive plates of the jaw members 110 and 120 are configured to limit and/or reduce many of the known undesirable effects related to tissue sealing, e.g., flashover, thermal spread and stray current dissipation.
With reference to Figs. 2-3, an energy-based cutting element or center electrode 130 is deployable between electrically conductive surfaces 112, 122, respectively.
The cutting element 130 may be an electrode configured to transmit electrosurgical energy, an ultrasonic probe configured to transmit ultrasonic energy or a thermal blade capable of transmitting heat to the tissue.
The cutting element 130 is attached to the jaw members 110 and 120 at two pivot points 131 and 132 respectively. The pivot points 131, 132 may include attachment mechanisms or mechanical interfaces 137, 139 (e.g., pins, shafts, etc.) which attach the cutting element 130 to the jaw members 110, 120 allowing the cutting element 130 to rotate freely thereabout (e.g., pass through holes). The pivot points 131, 132 may also include grooves or guides 117, 127 within the jaw members 110, 120 which allow the ends of the cutting element 130 to move freely during transitioning between open and close positions of the jaw members 110, 120.
It is envisioned that the cutting element 130 can be shaped in a variety of geometrical configurations to provide an optimal cutting surface. For instance, the cutting element 130 may have a circular, rectangular, triangular horizontal cross section.
The pivot points 131, 132 are positioned at opposite ends of jaw members 110 and 120, respectively. More specifically, pivot point 131 is positioned at a distal end 116 of the jaw member 110 and pivot point 132 is positioned at a proximal end of the jaw member 120. The pivots 131, 132 move within groves on guides 117, 127 in jaw members 110, 120 respectively.
This configuration allows the cutting element 130 to be automatically deployed when the jaw members 110, 120 are in open position so that the cutting element 130 intersects the center plane "C." It is envisioned that the pivot points 131, 132 may be oriented in a plurality of ways which permit the cutting element 130 to be deployed at various angles "a" when the jaw members 110, 120 are open. For instance, the pivot point 131 may be disposed more towards the proximal end of jaw member 110 to increase the cutting angle the pivot point 132 may be disposed more towards the distal end of jaw member 120 depending upon a particular purpose.
The cutting angle may also be dependent in the relative opening of the jaw members 110, 120, i.e., the relative distance between the jaw members 110, 120 when opened.
As shown in Fig. 3A, the electrically conductive surfaces 112, 122 may include electrically conductive plates 140, 142, 144, 146. This permits the cutting element 130 to be attached to the jaw members 110, 120 in an unimpeded fashion, i.e., without contacting the conductive surfaces 112, 122. It is envisioned that the electrically conductive surfaces 112, 122 may include any number of electrically conductive plates, such as for instance, a single electrically conductive plate 148, 150 disposed on each jaw member 110, 120, as shown in Fig.
3B, or eight plates (not shown), etc. The single electrically conductive plate 148 may be shaped in a number of forms, such as a "U" shape, a "H" shape. It is also envisioned that the electrically conductive plate 148 may be oriented in a plurality of ways. In addition, the single conductive plate 148 may be shaped to substantially match the surface of the jaw members 110, 120 with an opening for the pivot points 131, 132.
The ability of the cutting element 130 to automatically fold and raise as the jaw members 110, 120 are opened and closed respectively, allows the forceps 10 to have two modes of operation: a sealing mode and a cutting mode. During sealing mode, the jaw members 110 and 120 are clamped down in direction F as shown in Fig. 4 around tissue. The cutting element 130 folds down and the electrically conductive plates 140, 142, 144, 146 are energized thereby sealing tissue. Clamping of the jaw members 110, 120 is accomplished by moving the handle 40 relative to the fixed handle 50 to actuate the end effector assembly 100. The electrically conductive plates 140, 142, 144, 146 may be selectively energized once the jaw members 110, 120 are closed about tissue. The center electrode 130 in its folding orientation may be energized when the jaw members are closed to allow the user to selectively ct tissue after the seal has been formed. Alternatively, the center electrode or cutting element 130 may be energized when the jaw members are closed about tissue without prior sealing. It is envisioned that an alarm (not shown) may be included in this instance to warn the user that the tissue has not been treated prior to separation.
During an open cutting mode the jaw members 110 and 120 are open such that the cutting element 130 automatically deploys therebetween. As shown in Figs. 1-4, forceps 10 also includes a trigger 70 which activates the generator 500 to supply electrosurgical energy or other types of energy depending on the type of the cutting element 130 used (e.g., ultrasonic, heat, etc.). The forceps 10 may be manually pushed toward and into tissue 400 as shown in Fig. 2 while the cutting element 130 is energized, thereby dividing the tissue along the longitudinal axis of the forceps 10.
From the foregoing and with reference to the various figure drawings, those skilled in the art will appreciate that certain modifications can also be made to the present disclosure without departing from the scope of the same. For example and as mentioned above, it is contemplated that any of the various jaw arrangements and cutting elements disclosed herein may be employed on an open forceps such as the open forceps 700 shown in Fig. 5. The forceps 700 includes an end effector assembly 600 which is attached to the distal ends 516a and 516b of shafts 512a and 512b, respectively. The end effector assembly 600 includes pair of opposing jaw members 610 and 620 which are pivotally connected about a pivot pin 665 and which are movable relative to one another to grasp vessels and/or tissue. Each of the opposing jaw members 610, 620 include electrically conductive surfaces 112, 122 and cutting element 130 disposed therebetween. When in an open configuration, the cutting element 130 deployed and the open forceps 700 may be used for dividing tissue when the cutting element 130 is selectively energized similar to the endoscopic forceps 10 described above. The open forceps 700 may also be used for clamping tissue for sealing, coagulation or cauterization without energizing the cutting element 130.
Each shaft 512a and 512b includes a handle 515 and 517, respectively, disposed at the proximal end 514a and 514b thereof which each define a finger hole 515a and 517a, respectively, therethrough for receiving a finger of the user. Finger holes 515a and 517a facilitate movement of the shafts 512a and 512b relative to one another which, in turn, pivot the jaw members 610 and 620 from an open position wherein the jaw members 610 and 620 are disposed in spaced relation relative to one another to a clamping or closed position wherein the jaw members 610 and 620 cooperate to grasp tissue or vessels therebetween.
Further details relating to one particular open forceps are disclosed in commonly-owned U.S.
Application Serial No. 10/962,116 filed October 8, 2004 entitled "OPEN VESSEL SEALING
INSTRUMENT WITH CUTTING MECHANISM AND DISTAL LOCKOUT", the entire contentsof which being incorporated by reference herein.
While several embodiments of the disclosure have been shown in the drawings and/or discussed herein, it is not intended that the disclosure be limited thereto, as it is intended that the disclosure be as broad in scope as the art will allow and that the specification be read likewise. Therefore, the above description should not be construed as limiting, but merely as exemplifications of particular embodiments. Those skilled in the art will envision other modifications within the scope and spirit of the claims appended hereto.
Claims (18)
1. An electrosurgical bipolar forceps for treating tissue, comprising:
at least one shaft member having an end effector assembly disposed at a distal end thereof, the end effector assembly including two jaw members movable from a first position in spaced relation relative to one another to at least one subsequent position wherein the jaw members cooperate to grasp tissue therebetween;
each of the jaw members including an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween; and an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members, said energy-based cutting element being moveable from a first configuration adjacently between said jaw members when said jaw members are disposed in said first position to a second configuration wherein said energy-based cutting element is disposed at an angle between said jaw members.
at least one shaft member having an end effector assembly disposed at a distal end thereof, the end effector assembly including two jaw members movable from a first position in spaced relation relative to one another to at least one subsequent position wherein the jaw members cooperate to grasp tissue therebetween;
each of the jaw members including an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween; and an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members, said energy-based cutting element being moveable from a first configuration adjacently between said jaw members when said jaw members are disposed in said first position to a second configuration wherein said energy-based cutting element is disposed at an angle between said jaw members.
2. An electrosurgical bipolar forceps for sealing and dividing tissue as in claim 1, wherein each of the electrically conductive surfaces comprises at least one electrically conductive sealing plate.
3. An electrosurgical bipolar forceps for sealing and dividing tissue as in claim 1, wherein the energy-based cutting element when disposed at an angle is configured for dividing tissue upon selective activation of the second energy source.
4. An electrosurgical bipolar forceps for sealing and dividing tissue as in claim 1, wherein the energy-based cutting element is an electrode configured to transmit electrosurgical energy.
5. An electrosurgical bipolar forceps for sealing and dividing tissue as in claim 1, wherein the energy-based cutting element is an ultrasonic probe configured to transmit ultrasonic energy.
6. An electrosurgical bipolar forceps for sealing and dividing tissue as in claim 1, wherein the energy-based cutting element is a thermal blade configured to transmit heat.
7. An electrosurgical bipolar forceps for sealing and dividing tissue as in claim 1, wherein the cutting element is attached to each of the jaw members at at least two pivot points, a first pivot point located on one of said jaw members and a second pivot point located on the other of said jaw members.
8. An electrosurgical bipolar forceps for sealing and dividing tissue as in claim 7, wherein each of the pivot points include mechanical interfaces which attach the cutting element to the respective jaw members allowing the cutting element to rotate freely thereabout.
9. An electrosurgical bipolar forceps for sealing and dividing tissue as in claim 7, wherein at least one of the pivot points is disposed at a proximal end of one of said jaw members and at least another of the pivot points is disposed at a distal end of the other of said jaw members.
10. An electrosurgical bipolar forceps for sealing and dividing tissue as in claim 1, further comprising:
a rotating assembly mechanically associated with the shaft member, wherein rotation of the rotating assembly imparts similar rotational movement to the shaft member and the end effector assembly.
a rotating assembly mechanically associated with the shaft member, wherein rotation of the rotating assembly imparts similar rotational movement to the shaft member and the end effector assembly.
11. A method for electrically cutting tissue comprising the steps of:
providing an electrosurgical bipolar forceps comprising two jaw members movable from a first position in spaced relation relative to one another to at least one subsequent position wherein the jaw members cooperate to grasp tissue therebetween, each of the jaw members including an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween, and an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members, said energy-based cutting element being moveable from a first configuration adjacently between said jaw members when said jaw members are disposed in said first position to a second configuration wherein said energy-based cutting element is disposed at an angle between said jaw members;
positioning the jaw members in the first position to deploy the energy-based cutting element;
supplying electrosurgical energy to the energy-based cutting element; and moving electrosurgical bipolar forceps to position the energy-based cutting element in operative proximity to tissue thereby cutting tissue.
providing an electrosurgical bipolar forceps comprising two jaw members movable from a first position in spaced relation relative to one another to at least one subsequent position wherein the jaw members cooperate to grasp tissue therebetween, each of the jaw members including an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween, and an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members, said energy-based cutting element being moveable from a first configuration adjacently between said jaw members when said jaw members are disposed in said first position to a second configuration wherein said energy-based cutting element is disposed at an angle between said jaw members;
positioning the jaw members in the first position to deploy the energy-based cutting element;
supplying electrosurgical energy to the energy-based cutting element; and moving electrosurgical bipolar forceps to position the energy-based cutting element in operative proximity to tissue thereby cutting tissue.
12. A method for electrically cutting tissue according to claim 11, The electrosurgical bipolar forceps for sealing and dividing tissue as in claim 1, wherein each of the electrically conductive surfaces comprises at least one electrically conductive sealing plate.
13. A method for electrically cutting tissue according to claim 11, wherein the energy-based cutting element when disposed at an angle is configured for dividing tissue upon selective activation of the second energy source.
14. A method for electrically cutting tissue according to claim 11, wherein the cutting element is attached to each of the jaw members at least two pivot points, a first pivot point located on one of said jaw members and a second pivot point located on the other of said jaw members.
15. A method for electrically cutting tissue according to claim 14, wherein each of the pivot points include mechanical interfaces which attach the cutting element to the respective jaw members allowing the cutting element to rotate freely thereabout.
16. A method for electrically cutting tissue according to claim 14, wherein at least one of the pivot points is disposed at a proximal end of one of said jaw members and at least another of the pivot points is disposed at a distal end of the other of said jaw members.
17. A method for electrically cutting tissue, further comprising the steps of:
providing an electrosurgical bipolar forceps comprising two jaw members movable from a first position in spaced relation relative to one another to at least one subsequent position wherein the jaw members cooperate to grasp tissue therebetween, each of the jaw members including an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween, and an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members, said energy-based cutting element being moveable from a first configuration adjacently between said jaw members when said jaw members are disposed in said first position to a second configuration wherein said energy-based cutting element is disposed at an angle between said jaw members;
positioning the jaw members into said at least one subsequent position wherein the jaw members cooperate to grasp tissue therebetween; and communicating electrosurgical energy through tissue held therebetween thereby sealing tissue.
providing an electrosurgical bipolar forceps comprising two jaw members movable from a first position in spaced relation relative to one another to at least one subsequent position wherein the jaw members cooperate to grasp tissue therebetween, each of the jaw members including an electrically conductive surface adapted to connect to a first energy source which communicates electrosurgical energy through tissue held therebetween, and an energy-based cutting element adapted to connect to a second energy source and disposed between the jaw members, said energy-based cutting element being moveable from a first configuration adjacently between said jaw members when said jaw members are disposed in said first position to a second configuration wherein said energy-based cutting element is disposed at an angle between said jaw members;
positioning the jaw members into said at least one subsequent position wherein the jaw members cooperate to grasp tissue therebetween; and communicating electrosurgical energy through tissue held therebetween thereby sealing tissue.
18
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US11/285,432 US7594916B2 (en) | 2005-11-22 | 2005-11-22 | Electrosurgical forceps with energy based tissue division |
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CA2568420A1 true CA2568420A1 (en) | 2007-05-22 |
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-
2005
- 2005-11-22 US US11/285,432 patent/US7594916B2/en not_active Expired - Fee Related
-
2006
- 2006-11-20 CA CA002568420A patent/CA2568420A1/en not_active Abandoned
- 2006-11-21 AU AU2006241291A patent/AU2006241291A1/en not_active Abandoned
- 2006-11-21 EP EP06024123A patent/EP1787597B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1787597A1 (en) | 2007-05-23 |
AU2006241291A1 (en) | 2007-06-07 |
US7594916B2 (en) | 2009-09-29 |
US20070118111A1 (en) | 2007-05-24 |
EP1787597B1 (en) | 2012-10-24 |
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