CA2576344A1 - Warming compositions and delivery systems therefor - Google Patents
Warming compositions and delivery systems therefor Download PDFInfo
- Publication number
- CA2576344A1 CA2576344A1 CA002576344A CA2576344A CA2576344A1 CA 2576344 A1 CA2576344 A1 CA 2576344A1 CA 002576344 A CA002576344 A CA 002576344A CA 2576344 A CA2576344 A CA 2576344A CA 2576344 A1 CA2576344 A1 CA 2576344A1
- Authority
- CA
- Canada
- Prior art keywords
- warming
- comestible
- food
- agent
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000010792 warming Methods 0.000 title claims abstract 60
- 239000000203 mixture Substances 0.000 title claims abstract 41
- 229920000642 polymer Polymers 0.000 claims abstract 25
- 239000011159 matrix material Substances 0.000 claims abstract 10
- 230000035807 sensation Effects 0.000 claims abstract 8
- 238000013270 controlled release Methods 0.000 claims abstract 5
- 238000000034 method Methods 0.000 claims abstract 5
- 239000003795 chemical substances by application Substances 0.000 claims 24
- ZENOXNGFMSCLLL-UHFFFAOYSA-N vanillyl alcohol Chemical compound COC1=CC(CO)=CC=C1O ZENOXNGFMSCLLL-UHFFFAOYSA-N 0.000 claims 16
- 241000124008 Mammalia Species 0.000 claims 7
- 235000019615 sensations Nutrition 0.000 claims 6
- 239000007937 lozenge Substances 0.000 claims 5
- 210000002438 upper gastrointestinal tract Anatomy 0.000 claims 5
- 229940112822 chewing gum Drugs 0.000 claims 4
- 235000015218 chewing gum Nutrition 0.000 claims 4
- 235000009508 confectionery Nutrition 0.000 claims 4
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 claims 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 3
- 239000000796 flavoring agent Substances 0.000 claims 3
- 235000019634 flavors Nutrition 0.000 claims 3
- 235000010987 pectin Nutrition 0.000 claims 3
- 229920001277 pectin Polymers 0.000 claims 3
- 239000001814 pectin Substances 0.000 claims 3
- SZNYYWIUQFZLLT-UHFFFAOYSA-N 2-methyl-1-(2-methylpropoxy)propane Chemical compound CC(C)COCC(C)C SZNYYWIUQFZLLT-UHFFFAOYSA-N 0.000 claims 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 2
- AKDLSISGGARWFP-UHFFFAOYSA-N Homodihydrocapsaicin Chemical compound COC1=CC(CNC(=O)CCCCCCCC(C)C)=CC=C1O AKDLSISGGARWFP-UHFFFAOYSA-N 0.000 claims 2
- VQEONGKQWIFHMN-UHFFFAOYSA-N Nordihydrocapsaicin Chemical compound COC1=CC(CNC(=O)CCCCCC(C)C)=CC=C1O VQEONGKQWIFHMN-UHFFFAOYSA-N 0.000 claims 2
- CZNLTCTYLMYLHL-UHFFFAOYSA-N [6]-Paradol Chemical compound CCCCCCCC(=O)CCC1=CC=C(O)C(OC)=C1 CZNLTCTYLMYLHL-UHFFFAOYSA-N 0.000 claims 2
- 235000013361 beverage Nutrition 0.000 claims 2
- YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical compound COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 claims 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims 2
- 235000003599 food sweetener Nutrition 0.000 claims 2
- 229920001477 hydrophilic polymer Polymers 0.000 claims 2
- 229920001600 hydrophobic polymer Polymers 0.000 claims 2
- PHTQWCKDNZKARW-UHFFFAOYSA-N isoamylol Chemical compound CC(C)CCO PHTQWCKDNZKARW-UHFFFAOYSA-N 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 239000003765 sweetening agent Substances 0.000 claims 2
- 239000001993 wax Substances 0.000 claims 2
- OJYLAHXKWMRDGS-UHFFFAOYSA-N zingerone Chemical compound COC1=CC(CCC(C)=O)=CC=C1O OJYLAHXKWMRDGS-UHFFFAOYSA-N 0.000 claims 2
- OQWKEEOHDMUXEO-UHFFFAOYSA-N (6)-shogaol Natural products CCCCCC=CC(=O)CCC1=CC=C(O)C(OC)=C1 OQWKEEOHDMUXEO-UHFFFAOYSA-N 0.000 claims 1
- KJPRLNWUNMBNBZ-QPJJXVBHSA-N (E)-cinnamaldehyde Chemical compound O=C\C=C\C1=CC=CC=C1 KJPRLNWUNMBNBZ-QPJJXVBHSA-N 0.000 claims 1
- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 claims 1
- BPIUIOXAFBGMNB-UHFFFAOYSA-N 1-hexoxyhexane Chemical compound CCCCCCOCCCCCC BPIUIOXAFBGMNB-UHFFFAOYSA-N 0.000 claims 1
- 206010006784 Burning sensation Diseases 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 claims 1
- 229920000742 Cotton Polymers 0.000 claims 1
- 229920001353 Dextrin Polymers 0.000 claims 1
- 239000004375 Dextrin Substances 0.000 claims 1
- AQZGPSLYZOOYQP-UHFFFAOYSA-N Diisoamyl ether Chemical compound CC(C)CCOCCC(C)C AQZGPSLYZOOYQP-UHFFFAOYSA-N 0.000 claims 1
- ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 claims 1
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 claims 1
- 239000005770 Eugenol Substances 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- 229930186217 Glycolipid Natural products 0.000 claims 1
- 102000003886 Glycoproteins Human genes 0.000 claims 1
- 108090000288 Glycoproteins Proteins 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 239000004698 Polyethylene Substances 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- AXMVYSVVTMKQSL-UHFFFAOYSA-N UNPD142122 Natural products OC1=CC=C(C=CC=O)C=C1O AXMVYSVVTMKQSL-UHFFFAOYSA-N 0.000 claims 1
- OQWKEEOHDMUXEO-BQYQJAHWSA-N [6]-Shogaol Chemical compound CCCCC\C=C\C(=O)CCC1=CC=C(O)C(OC)=C1 OQWKEEOHDMUXEO-BQYQJAHWSA-N 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- QQQCWVDPMPFUGF-ZDUSSCGKSA-N alpinetin Chemical compound C1([C@H]2OC=3C=C(O)C=C(C=3C(=O)C2)OC)=CC=CC=C1 QQQCWVDPMPFUGF-ZDUSSCGKSA-N 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 235000019445 benzyl alcohol Nutrition 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 229960002504 capsaicin Drugs 0.000 claims 1
- 235000017663 capsaicin Nutrition 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 229920001525 carrageenan Polymers 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 235000010980 cellulose Nutrition 0.000 claims 1
- 229940117916 cinnamic aldehyde Drugs 0.000 claims 1
- KJPRLNWUNMBNBZ-UHFFFAOYSA-N cinnamic aldehyde Natural products O=CC=CC1=CC=CC=C1 KJPRLNWUNMBNBZ-UHFFFAOYSA-N 0.000 claims 1
- 239000010630 cinnamon oil Substances 0.000 claims 1
- 239000002826 coolant Substances 0.000 claims 1
- 235000019425 dextrin Nutrition 0.000 claims 1
- XJQPQKLURWNAAH-UHFFFAOYSA-N dihydrocapsaicin Chemical compound COC1=CC(CNC(=O)CCCCCCC(C)C)=CC=C1O XJQPQKLURWNAAH-UHFFFAOYSA-N 0.000 claims 1
- RBCYRZPENADQGZ-UHFFFAOYSA-N dihydrocapsaicin Natural products COC1=CC(COC(=O)CCCCCCC(C)C)=CC=C1O RBCYRZPENADQGZ-UHFFFAOYSA-N 0.000 claims 1
- 229960002217 eugenol Drugs 0.000 claims 1
- 239000003925 fat Substances 0.000 claims 1
- NLDDIKRKFXEWBK-AWEZNQCLSA-N gingerol Chemical compound CCCCC[C@H](O)CC(=O)CCC1=CC=C(O)C(OC)=C1 NLDDIKRKFXEWBK-AWEZNQCLSA-N 0.000 claims 1
- JZLXEKNVCWMYHI-UHFFFAOYSA-N gingerol Natural products CCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1 JZLXEKNVCWMYHI-UHFFFAOYSA-N 0.000 claims 1
- 235000002780 gingerol Nutrition 0.000 claims 1
- 230000009477 glass transition Effects 0.000 claims 1
- 235000011187 glycerol Nutrition 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- MLJGZARGNROKAC-VQHVLOKHSA-N homocapsaicin Chemical compound CCC(C)\C=C\CCCCC(=O)NCC1=CC=C(O)C(OC)=C1 MLJGZARGNROKAC-VQHVLOKHSA-N 0.000 claims 1
- JKIHLSTUOQHAFF-UHFFFAOYSA-N homocapsaicin Natural products COC1=CC(CNC(=O)CCCCCC=CC(C)C)=CC=C1O JKIHLSTUOQHAFF-UHFFFAOYSA-N 0.000 claims 1
- JZNZUOZRIWOBGG-UHFFFAOYSA-N homocapsaicin-II Natural products COC1=CC(CNC(=O)CCCCC=CCC(C)C)=CC=C1O JZNZUOZRIWOBGG-UHFFFAOYSA-N 0.000 claims 1
- GOBFKCLUUUDTQE-UHFFFAOYSA-N homodihydrocapsaicin-II Natural products CCC(C)CCCCCCC(=O)NCC1=CC=C(O)C(OC)=C1 GOBFKCLUUUDTQE-UHFFFAOYSA-N 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000011777 magnesium Substances 0.000 claims 1
- 229910052749 magnesium Inorganic materials 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 125000002467 phosphate group Chemical class [H]OP(=O)(O[H])O[*] 0.000 claims 1
- -1 polyethylene Polymers 0.000 claims 1
- 229920000573 polyethylene Polymers 0.000 claims 1
- 229920002959 polymer blend Polymers 0.000 claims 1
- 229920002689 polyvinyl acetate Polymers 0.000 claims 1
- 239000011118 polyvinyl acetate Substances 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- KOCVACNWDMSLBM-UHFFFAOYSA-N vanillyl alcohol ethyl ether Natural products CCOCC1=CC=C(O)C(OC)=C1 KOCVACNWDMSLBM-UHFFFAOYSA-N 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/44—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/10—Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/14—Chewing gum characterised by the composition containing organic or inorganic compounds containing peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention includes compositions for imparting a controlled-release warming sensation to the oral receptor areas of a user. The oral, controlled-release warming compositions include a warming agent and a hydrated or swollen food-grade polymer which forms a matrix with the warming agent. Also included are oral delivery systems for the warming compositions, methods for preparing same, and methods for imparting and sustaining a warming sensation in the mouth and upper portion of the gastrointestinal tract of the user.
Claims (39)
1. An oral, controlled-release warming composition, comprising:
a) a warming agent; and b) a hydrated food-grade polymer which forms a non-particulate matrix with said warming agent.
a) a warming agent; and b) a hydrated food-grade polymer which forms a non-particulate matrix with said warming agent.
2. The warming composition according to claim 1, wherein said food-grade polymer is present in an amount sufficient to produce a warming sensation in the mouth and upper gastrointestinal tract of a mammal extending from about 2 seconds to about 30 minutes.
3. The warming composition according to claim 1, wherein said food-grade polymer is present in an amount sufficient to sustain a warming sensation in the mouth and upper gastrointestinal tract of a mammal for about 1 to 3 minutes after said warming composition has been substantially consumed without imparting a burning sensation thereto.
4. The warming composition according to claim 1, wherein said food-grade polymer is present in an amount of about 0.05% to about 99% by weight of said composition.
5. The warming composition according to claim 1, wherein said food-grade polymer is present in an amount of about 1% to about 10% by weight of said composition.
6. The warming composition according to claim 1, wherein said food-grade polymer is selected from the group consisting of proteins, glycoproteins, glycolipids, fats, waxes, polyvinyl acetate, polyethylene oxide, polyethylene, dextrins, fructo-oligosaccharides, starches, alginates, natural and synthetic gums, celluloses, carrageenans and combinations thereof.
7. The warming composition according to claim 1, wherein said food-grade polymer comprises pectin.
8. The warming composition according to claim 7, wherein said pectin is present in an amount of about 0.05% to about 10% by weight of said composition.
9. The warming composition according to claim 1, wherein said food-grade polymer has a molecular weight of at least about 180 Daltons.
10. The warming composition according to claim 1, wherein said food-grade polymer has a molecular weight of less than about 3 million Daltons.
11. The warming composition according to claim 1, wherein said food-grade polymer has a viscosity of about 5 to about 100,000 cP.
12. The warming composition according to claim 1, wherein said warming agent comprises at least one allyl vinyl component.
13. The warming composition according to claim 1, wherein said warming agent is selected from the group consisting of: vanillyl alcohol n-butylether; vanillyl alcohol n-propylether; vanillyl alcohol isopropylether; vanillyl alcohol isobutylether;
vanillyl alcohol n-aminoether; vanillyl alcohol isoamylether; vanillyl alcohol n-hexylether;
vanillyl alcohol methylether; vanillyl alcohol ethylether; gingerol; shogaol; paradol;
zingerone; capsaicin;
dihydrocapsaicin; nordihydrocapsaicin; homocapsaicin; homodihydrocapsaicin;
ethanol;
isopropyl alcohol; iso-amylalcohol; benzyl alcohol; glycerine; chloroform;
eugenol;
cinnamon oil; cinnamic aldehyde; phosphate derivatives thereof; and combinations thereof.
vanillyl alcohol n-aminoether; vanillyl alcohol isoamylether; vanillyl alcohol n-hexylether;
vanillyl alcohol methylether; vanillyl alcohol ethylether; gingerol; shogaol; paradol;
zingerone; capsaicin;
dihydrocapsaicin; nordihydrocapsaicin; homocapsaicin; homodihydrocapsaicin;
ethanol;
isopropyl alcohol; iso-amylalcohol; benzyl alcohol; glycerine; chloroform;
eugenol;
cinnamon oil; cinnamic aldehyde; phosphate derivatives thereof; and combinations thereof.
14. The warming composition according to claim 1, wherein said warming agent is present in an amount of about 0.1% to about 96% by weight of said composition.
15. The warming composition according to claim 1, wherein said warming agent is present in an amount of about 5% to about 25% by weight of said composition.
16. The warming composition according to claim 1, further comprising a flavor agent.
17. The warming composition according to claim 1, further comprising an enhancement component.
18. The warming composition according to claim 17, wherein said enhancement component is selected from the group consisting of: a mineral cation selected from the group consisting of magnesium, sodium, calcium, and potassium; a physiological cooling agent; and combinations thereof.
19. An oral, controlled-release warming composition, comprising:
a) a warming agent; and b) a swollen food-grade polymer which forms a non-particulate matrix with said warming agent.
a) a warming agent; and b) a swollen food-grade polymer which forms a non-particulate matrix with said warming agent.
20. An oral warming composition, comprising:
a warming agent dispersed in a hydrated food-grade polymer blend comprising a hydrophilic polymer and a hydrophobic polymer.
a warming agent dispersed in a hydrated food-grade polymer blend comprising a hydrophilic polymer and a hydrophobic polymer.
21. The warming composition according to claim 20, wherein said hydrophilic polymer comprises a protein and said hydrophobic polymer comprises a wax.
22. A comestible comprising:
a) an oral warming composition comprising a warming agent and a hydrated food-grade polymer which forms a non-particulate matrix with said warming agent;
b) a flavor agent; and c) a carrier.
a) an oral warming composition comprising a warming agent and a hydrated food-grade polymer which forms a non-particulate matrix with said warming agent;
b) a flavor agent; and c) a carrier.
23. The comestible according to claim 22, wherein said food-grade polymer is present in an amount of about 0.2% to about 95% by weight of said comestible.
24. The comestible according to claim 22, wherein said food-grade polymer is present in an amount of about 0.2% to about 0.4% by weight of said comestible.
25. The comestible according to claim 22, wherein said food-grade polymer has a glass transition temperature of about -50°C to about 80°C.
26. The comestible according to claim 22, wherein said warming agent is present in an amount of about 0.001% to about 10% by weight of said comestible.
27. The comestible according to claim 22, wherein said warming agent is present in an amount of about 0.4% to about 0.6% by weight of said comestible.
28. The comestible according to claim 22, further comprising an enhancement component, and wherein said warming agent is present in an amount of about 0.01% to about 0.1% by weight of said comestible.
29. The comestible according to claim 22, wherein said comestible is selected from the group consisting of: hard candy; soft candy; cotton candy; pressed tablet;
chewing gum;
lozenge; liquid beverage; powdered beverage; film; and center-filled confectionery.
chewing gum;
lozenge; liquid beverage; powdered beverage; film; and center-filled confectionery.
30. The comestible according to claim 22, wherein:
said comestible comprises a lozenge; and said carrier comprises a bulk sweetener selected from the group consisting of sugars, sugarless bulk sweeteners and combinations thereof.
said comestible comprises a lozenge; and said carrier comprises a bulk sweetener selected from the group consisting of sugars, sugarless bulk sweeteners and combinations thereof.
31. The comestible according to claim 22, wherein said comestible comprises chewing gum and said carrier comprises a gum base.
32. A lozenge composition comprising:
a glassy polymer matrix having a warming agent dispersed therein.
a glassy polymer matrix having a warming agent dispersed therein.
33. The lozenge composition according to claim 32, wherein said glassy polymer matrix comprises a hydrated food-grade polymer present in an amount sufficient to produce a warming sensation in the mouth and upper gastrointestinal tract of a mammal extending from about 2 seconds to about 30 minutes.
34. The lozenge composition according to claim 33, wherein said glassy polymer matrix comprises pectin present in an amount of about 0.2% to about 0.4% by weight of said composition.
35. A chewing gum composition comprising:
a) an oral warming composition comprising a warming agent and a hydrated food-grade polymer which forms a non-particulate matrix with said warming agent;
b) a flavor agent; and c) a gum base, wherein said food-grade polymer is present in an amount sufficient to produce a warming sensation in the mouth and upper gastrointestinal tract of a mammal extending from about 2 seconds to about 1 hour.
a) an oral warming composition comprising a warming agent and a hydrated food-grade polymer which forms a non-particulate matrix with said warming agent;
b) a flavor agent; and c) a gum base, wherein said food-grade polymer is present in an amount sufficient to produce a warming sensation in the mouth and upper gastrointestinal tract of a mammal extending from about 2 seconds to about 1 hour.
36. The chewing gum composition according to claim 35, wherein said warming agent is present in an amount of about 0.001% to about 10% by weight of said composition.
37. A method of imparting a warming sensation to oral receptor areas of a mammal, comprising the steps of:
orally administering a warming composition comprising a warming agent and a hydrated food-grade polymer which forms a non-particulate matrix with the warming agent;
and stimulating the oral receptor areas within about 2 to about 45 seconds to produce a warming sensation in the mouth and upper gastrointestinal tract of the mammal.
orally administering a warming composition comprising a warming agent and a hydrated food-grade polymer which forms a non-particulate matrix with the warming agent;
and stimulating the oral receptor areas within about 2 to about 45 seconds to produce a warming sensation in the mouth and upper gastrointestinal tract of the mammal.
38. The method according to claim 37, wherein the oral receptor areas comprise receptors in the mouth and throat of the mammal.
39. A method of preparing a comestible having controlled-release warming properties, comprising the steps of:
heating a carrier with an aqueous solution of a hydrated food-grade polymer until the carrier changes from a crystalline phase to an amorphous or a glassy phase;
dispersing a warming agent in the polymer to form a non-particulate matrix;
and forming a comestible from the combination of components in the glassy phase.
heating a carrier with an aqueous solution of a hydrated food-grade polymer until the carrier changes from a crystalline phase to an amorphous or a glassy phase;
dispersing a warming agent in the polymer to form a non-particulate matrix;
and forming a comestible from the combination of components in the glassy phase.
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PCT/US2005/028371 WO2006020686A1 (en) | 2004-08-11 | 2005-08-10 | Warming compositions and delivery systems therefor |
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DE602005023836D1 (en) | 2004-02-26 | 2010-11-11 | Wrigley W M Jun Co | DELIVERIES INCLUDED |
US7189760B2 (en) | 2004-04-02 | 2007-03-13 | Millennium Specialty Chemicals | Physiological cooling compositions containing highly purified ethyl ester of N-[[5-methyl-2-(1-methylethyl) cyclohexyl] carbonyl]glycine |
US20090022846A1 (en) | 2004-06-30 | 2009-01-22 | Helle Wittorff | Chewing Gum Comprising Flavor Emulsion |
US20050196517A1 (en) * | 2005-02-14 | 2005-09-08 | Mars, Incorporated | Edible product having discrete regions with different heats of solution |
US20070036733A1 (en) * | 2005-08-12 | 2007-02-15 | Takasago International Corp. (Usa) | Sensation masking composition |
US20070048424A1 (en) | 2005-09-01 | 2007-03-01 | Moza Ashok K | Liquid composition of 2-Isopropyl-N,2,3-trimethylbutyramide and N-Ethyl-p-menthane-3-carboxamide, its preparation method and its applications as a cooling agent and flavor enhancer |
-
2005
- 2005-08-10 EP EP05784203A patent/EP1806971A1/en not_active Withdrawn
- 2005-08-10 CA CA2576375A patent/CA2576375C/en not_active Expired - Fee Related
- 2005-08-10 PL PL05788066T patent/PL1786272T3/en unknown
- 2005-08-10 AU AU2005272802A patent/AU2005272802B2/en not_active Ceased
- 2005-08-10 RU RU2007108787/13A patent/RU2351148C2/en active
- 2005-08-10 BR BRPI0514283-0A patent/BRPI0514283A/en not_active Application Discontinuation
- 2005-08-10 WO PCT/US2005/028516 patent/WO2006020754A1/en active Application Filing
- 2005-08-10 EP EP05788066.8A patent/EP1786272B1/en active Active
- 2005-08-10 RU RU2007108793/13A patent/RU2350091C2/en active
- 2005-08-10 BR BRPI0513465-0A patent/BRPI0513465B1/en not_active IP Right Cessation
- 2005-08-10 WO PCT/US2005/028371 patent/WO2006020686A1/en active Application Filing
- 2005-08-10 US US11/200,748 patent/US8101208B2/en active Active
- 2005-08-10 AU AU2005272922A patent/AU2005272922B2/en not_active Ceased
- 2005-08-10 US US11/201,370 patent/US8097271B2/en active Active
- 2005-08-10 ES ES05788066.8T patent/ES2525320T3/en active Active
- 2005-08-10 JP JP2007525783A patent/JP4964773B2/en active Active
- 2005-08-10 MX MX2007001611A patent/MX2007001611A/en active IP Right Grant
- 2005-08-10 CA CA2576344A patent/CA2576344C/en not_active Expired - Fee Related
- 2005-08-10 MX MX2007001609A patent/MX2007001609A/en active IP Right Grant
- 2005-08-10 JP JP2007525751A patent/JP2008509665A/en active Pending
- 2005-08-11 AR ARP050103343A patent/AR050117A1/en not_active Application Discontinuation
- 2005-08-11 AR ARP050103344A patent/AR050118A1/en not_active Application Discontinuation
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2009
- 2009-10-02 AU AU2009222553A patent/AU2009222553B2/en not_active Ceased
- 2009-10-02 AU AU2009222555A patent/AU2009222555B2/en not_active Ceased
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2011
- 2011-01-07 JP JP2011001958A patent/JP2011067220A/en active Pending
- 2011-04-20 AU AU2011201805A patent/AU2011201805B2/en not_active Ceased
- 2011-09-26 JP JP2011209944A patent/JP5058368B2/en active Active
- 2011-12-09 US US13/315,453 patent/US20120082755A1/en not_active Abandoned
- 2011-12-09 US US13/315,480 patent/US20120087874A1/en not_active Abandoned
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2012
- 2012-06-18 AR ARP120102157A patent/AR086970A2/en unknown
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8283338B2 (en) | 2007-11-30 | 2012-10-09 | Kao Corporation | GIP secretion inhibitor |
US8338389B2 (en) | 2009-06-17 | 2012-12-25 | Kao Corporation | Agent for preventing or ameliorating obesity |
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