CA2591834A1 - Determination of glycated hemoglobin by fluorescence quenching - Google Patents

Determination of glycated hemoglobin by fluorescence quenching Download PDF

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Publication number
CA2591834A1
CA2591834A1 CA002591834A CA2591834A CA2591834A1 CA 2591834 A1 CA2591834 A1 CA 2591834A1 CA 002591834 A CA002591834 A CA 002591834A CA 2591834 A CA2591834 A CA 2591834A CA 2591834 A1 CA2591834 A1 CA 2591834A1
Authority
CA
Canada
Prior art keywords
glycated hemoglobin
determination
measurement
fluorescence quenching
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002591834A
Other languages
French (fr)
Other versions
CA2591834C (en
Inventor
Douglas R. Brandt
William E. Brown
Theresa L. Lane
David H. Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Douglas R. Brandt
William E. Brown
Theresa L. Lane
David H. Wilson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories, Douglas R. Brandt, William E. Brown, Theresa L. Lane, David H. Wilson filed Critical Abbott Laboratories
Publication of CA2591834A1 publication Critical patent/CA2591834A1/en
Application granted granted Critical
Publication of CA2591834C publication Critical patent/CA2591834C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive

Abstract

The present invention relates to the measurement of glycated hemoglobin by fluorescence quenching. The present invention uniquely involves performing two sequential fluorescent quenching measurements: one measurement of the fluorescent quenching due to total hemoglobin in the sample and a second measurement of the fluorescent quenching due to glycated hemoglobin present in the sample after the non-glycated hemoglobin is removed. Glycated hemoglobin and non-glycated hemoglobin can be separated by a variety of methods as described herein, including ion capture and solid phase separations.
CA002591834A 1992-03-04 1993-03-03 Determination of glycated hemoglobin by fluorescence quenching Expired - Fee Related CA2591834C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84590892A 1992-03-04 1992-03-04
US845,908 1992-03-04
CA002102417A CA2102417C (en) 1992-03-04 1993-03-03 Determination of glycated hemoglobin by fluorescence quenching

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002102417A Division CA2102417C (en) 1992-03-04 1993-03-03 Determination of glycated hemoglobin by fluorescence quenching

Publications (2)

Publication Number Publication Date
CA2591834A1 true CA2591834A1 (en) 1993-09-16
CA2591834C CA2591834C (en) 2009-04-28

Family

ID=25296390

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002102417A Expired - Fee Related CA2102417C (en) 1992-03-04 1993-03-03 Determination of glycated hemoglobin by fluorescence quenching
CA002591834A Expired - Fee Related CA2591834C (en) 1992-03-04 1993-03-03 Determination of glycated hemoglobin by fluorescence quenching

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002102417A Expired - Fee Related CA2102417C (en) 1992-03-04 1993-03-03 Determination of glycated hemoglobin by fluorescence quenching

Country Status (10)

Country Link
US (1) US5478754A (en)
EP (2) EP1239287A3 (en)
JP (1) JP3515782B2 (en)
AT (1) ATE221203T1 (en)
AU (1) AU3737093A (en)
CA (2) CA2102417C (en)
DE (1) DE69332138T2 (en)
DK (1) DK0589001T3 (en)
ES (1) ES2182826T3 (en)
WO (1) WO1993018407A1 (en)

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US5981716A (en) * 1995-06-07 1999-11-09 Gruppo Lepettit, S.P.A. Process for the purification of proteins
US6162645A (en) * 1997-03-13 2000-12-19 Abbott Laboratories Determination of % glycated hemoglobin
US6316265B1 (en) 1997-03-13 2001-11-13 Abbott Laboratories Determination of % glycated hemoglobin
WO1998054578A1 (en) * 1997-05-29 1998-12-03 Bio-Rad Laboratories, Inc. Chemiluminescent hemoglobin assay
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US6174734B1 (en) 1997-10-24 2001-01-16 Abbott Laboratories Measurement of glycated hemoglobin
US6294281B1 (en) 1998-06-17 2001-09-25 Therasense, Inc. Biological fuel cell and method
DE19843094A1 (en) * 1998-09-21 2000-03-23 Roche Diagnostics Gmbh Method for the determination of glycated hemoglobin
AU2001269513A1 (en) * 2000-07-14 2002-01-30 Arkray, Inc. Method of selectively determining glycated hemoglobin
WO2002018539A2 (en) * 2000-08-25 2002-03-07 Lysometrix Corporation Method for assaying the activity of lysosomal enzymes
US6677158B2 (en) * 2001-03-14 2004-01-13 Exocell Inc. Method for measurement of glycated hemoglobin by a rapid strip test procedure
US7005273B2 (en) * 2001-05-16 2006-02-28 Therasense, Inc. Method for the determination of glycated hemoglobin
US7368190B2 (en) * 2002-05-02 2008-05-06 Abbott Diabetes Care Inc. Miniature biological fuel cell that is operational under physiological conditions, and associated devices and methods
JP2007506946A (en) * 2003-09-23 2007-03-22 エピネックス・ダイアグノスティクス・インコーポレーテッド Rapid examination of glycoalbumin
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
GB2436681B (en) * 2006-03-31 2010-10-13 Quotient Diagnostics Ltd Fluorescent assay
GB0820817D0 (en) * 2008-11-13 2008-12-24 Wireless Biodevices Ltd Electrode, electrochemical sensor and apparatus, and methods for operating the same
US20100167306A1 (en) * 2008-12-26 2010-07-01 Henry John Smith Rapid test for glycated albumin in saliva
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
GB2474224A (en) * 2009-07-07 2011-04-13 Toximet Ltd Devices and methods using fluorescent polymers in solid phase extraction
US8603828B2 (en) 2009-11-18 2013-12-10 Bio-Rad Laboratories, Inc. Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms
KR20120051133A (en) * 2010-11-12 2012-05-22 삼성전자주식회사 Microfluidic device and hemoglobin measuring method thereof
WO2016071887A1 (en) * 2014-11-07 2016-05-12 Alifax S.R.L. Method to measure glycated hemoglobin
US10948500B2 (en) * 2015-12-30 2021-03-16 W. Health L.P. Method for determining the quantity of an HbA1c in a blood sample
CN109762163A (en) * 2019-01-11 2019-05-17 南京苏睿医药科技有限公司 It is a kind of carry Hyperoside synthesis and application method
WO2021182599A1 (en) * 2020-03-13 2021-09-16 積水メディカル株式会社 Hemoglobin assay method

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US4168147A (en) * 1977-12-02 1979-09-18 Isolab, Inc. Method to determine a diagnostic indicator of blood sugar condition, and, a liquid chromatographic microcolumn therefor
US4269605A (en) * 1978-06-28 1981-05-26 Amicon Corporation Method and kit for separation of glycoproteins
GB2024829B (en) * 1978-06-28 1982-08-04 Amicon Corp Method and product for separation of glycoproteins
US4243534A (en) * 1979-01-25 1981-01-06 Becton, Dickinson And Company Blood separation
US4255385A (en) * 1979-10-23 1981-03-10 Abbott Laboratories Reagent and test kit for determining glycosylated hemoglobin
US4238196A (en) * 1979-11-01 1980-12-09 Isolab, Inc. Methods to determine a diagnostic indicator of blood sugar conditions, and, liquid chromatographic columns therefor (cyanide free)
US4649122A (en) * 1980-09-02 1987-03-10 Leeco Diagnostics, Inc. Means for determining percentage of glycohemoglobin in whole blood
US4371374A (en) * 1980-11-17 1983-02-01 The Rockefeller University Monitoring metabolic control in diabetic patients by measuring glycosylated amino acids and peptides in urine
US4407961A (en) * 1981-03-16 1983-10-04 Sanders James L Ion-exchange system and method for isolation and determination of glycosylated hemoglobin in human blood
DE3141146A1 (en) * 1981-10-16 1983-04-28 Boehringer Mannheim Gmbh, 6800 Mannheim METHOD AND REAGENT FOR DETERMINING GLYCOSILED HAEMOGLOBIN
EP0104165A1 (en) * 1982-03-25 1984-04-04 SANDERS, James Lynn Ion-exchange system and method for isolation and determination of glycosylated hemoglobin in human blood
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US5116763A (en) * 1984-11-19 1992-05-26 Miles Inc. Nonenzymatic glucose test
GB2181840B (en) * 1985-10-16 1989-11-29 Farmos Group Ltd Method for the immunoassay of a macromolecular analyte
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US4861728A (en) * 1987-07-24 1989-08-29 Becton, Dickinson And Company Immunoassay of glycosylated hemoglobin using a labeled boron reagent
AU609241B2 (en) * 1988-01-29 1991-04-26 Abbott Laboratories Ion-capture assays and devices
US5110745A (en) * 1989-06-01 1992-05-05 The Trustees Of The University Of Pennsylvania Methods of detecting glycated proteins
CA1341592C (en) * 1989-07-07 2009-04-14 Abbott Laboratories Ion capture reagents and methods for performing binding assays
WO1992022818A1 (en) * 1991-06-19 1992-12-23 Abbott Laboratories Rapid determination of glycated hemoglobin

Also Published As

Publication number Publication date
US5478754A (en) 1995-12-26
JPH06507978A (en) 1994-09-08
EP0589001A1 (en) 1994-03-30
EP0589001A4 (en) 1996-01-31
EP0589001B1 (en) 2002-07-24
EP1239287A2 (en) 2002-09-11
JP3515782B2 (en) 2004-04-05
ATE221203T1 (en) 2002-08-15
ES2182826T3 (en) 2003-03-16
DE69332138D1 (en) 2002-08-29
CA2102417A1 (en) 1993-09-05
DK0589001T3 (en) 2002-11-04
WO1993018407A1 (en) 1993-09-16
EP1239287A3 (en) 2006-07-26
AU3737093A (en) 1993-10-05
CA2102417C (en) 2008-06-10
DE69332138T2 (en) 2003-03-27
CA2591834C (en) 2009-04-28

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