CA2638756A1 - Optical dose measurements in syringes - Google Patents

Optical dose measurements in syringes Download PDF

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Publication number
CA2638756A1
CA2638756A1 CA002638756A CA2638756A CA2638756A1 CA 2638756 A1 CA2638756 A1 CA 2638756A1 CA 002638756 A CA002638756 A CA 002638756A CA 2638756 A CA2638756 A CA 2638756A CA 2638756 A1 CA2638756 A1 CA 2638756A1
Authority
CA
Canada
Prior art keywords
syringe
dose
optical detector
datum
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002638756A
Other languages
French (fr)
Other versions
CA2638756C (en
Inventor
Stephen J. Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch Healthcare Systems Inc
Original Assignee
Raya Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Raya Systems Inc filed Critical Raya Systems Inc
Priority to CA2638756A priority Critical patent/CA2638756C/en
Publication of CA2638756A1 publication Critical patent/CA2638756A1/en
Application granted granted Critical
Publication of CA2638756C publication Critical patent/CA2638756C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31546—Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
    • G01F11/021—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type
    • G01F11/023—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type with provision for varying the stroke of the piston
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
    • G01F11/021—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type
    • G01F11/025—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type with manually operated pistons
    • G01F11/027—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type with manually operated pistons of the syringe type
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
    • G01F11/021—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type
    • G01F11/029—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type provided with electric controlling means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
    • G01F23/22—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water
    • G01F23/28—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water by measuring the variations of parameters of electromagnetic or acoustic waves applied directly to the liquid or fluent solid material
    • G01F23/284—Electromagnetic waves
    • G01F23/292—Light, e.g. infrared or ultraviolet
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F3/00—Measuring the volume flow of fluids or fluent solid material wherein the fluid passes through the meter in successive and more or less isolated quantities, the meter being driven by the flow
    • G01F3/02—Measuring the volume flow of fluids or fluent solid material wherein the fluid passes through the meter in successive and more or less isolated quantities, the meter being driven by the flow with measuring chambers which expand or contract during measurement
    • G01F3/04—Measuring the volume flow of fluids or fluent solid material wherein the fluid passes through the meter in successive and more or less isolated quantities, the meter being driven by the flow with measuring chambers which expand or contract during measurement having rigid movable walls
    • G01F3/14—Measuring the volume flow of fluids or fluent solid material wherein the fluid passes through the meter in successive and more or less isolated quantities, the meter being driven by the flow with measuring chambers which expand or contract during measurement having rigid movable walls comprising reciprocating pistons, e.g. reciprocating in a rotating body
    • G01F3/16—Measuring the volume flow of fluids or fluent solid material wherein the fluid passes through the meter in successive and more or less isolated quantities, the meter being driven by the flow with measuring chambers which expand or contract during measurement having rigid movable walls comprising reciprocating pistons, e.g. reciprocating in a rotating body in stationary cylinders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

An apparatus for optically measuring and electronically recording a dose is disclosed. A holding means receives and holds a syringe, which has a barrel and a plunger, in a measurement position. A light source in optical communication with the barrel and the plunger generates light incident on the barrel and the plunger when the syringe is in the measurement position. An optical detector is positioned to detect a total amount of the light that is reflected from the syringe. A recording means in electrical communication with the optical detector records a dose datum indicative of the total amount of the light that is transmitted. The dose datum is indicative of the dose. A response enhancing element, connected with the plunger of the syringe and in optical communication with the optical detector, reflects light to the optical detector proportional to the dose datum.

Claims (10)

1. An apparatus for optically measuring and electronically recording a dose, said apparatus comprising:
a) a holding means for receiving and holding a syringe in a measurement position, said syringe having a barrel and a plunger;
b) a light source in optical communication with the barrel and the plunger, said light source for generating light incident on the barrel and the plunger when the syringe is in the measurement position;
c) an optical detector positioned to detect a total amount of said light that is reflected from said syringe;
d) a recording means in electrical communication with said optical detector, said recording means for recording a dose datum indicative of said total amount of said light that is transmitted, wherein said dose datum is indicative of said dose; and e) a response enhancing element connected with the plunger of said syringe and in optical communication with said optical detector, whereby the response enhancing element reflects light to said optical detector proportional to said dose datum.
2. An apparatus as claimed in claim 1, further comprising an alignment means for aligning the syringe with said optical detector when the syringe is in the measurement position.
3. An apparatus as claimed in claim 1 or claim 2, further comprising a housing, said housing enclosing said light source, said optical detector, and said recording means;
wherein said housing is sufficiently compact to be hand-held and carried by a patient.
4. An apparatus as claimed in any one of claim 1 to claim 3, wherein said total amount of light transmitted is indicative of a quantity of liquid in the syringe, said quantity of liquid being indicative of the dose.
5. An apparatus as claimed in any one of claim 1 to claim 4, further comprising a light source for generating light incident on the syringe.
6. An apparatus as claimed in any one of claim 1 to claim 4, further comprising a computing means and a calibration memory means, said computing means in electrical communication with said optical detector, with said recording means, and with said calibration memory means.
7. An apparatus as claimed in any one of claim 1 to claim 6, further comprising a housing, wherein said optical detector occupies a fixed spatial relationship to said holding means, and said holding means is mechanically coupled to said housing.
8. An apparatus as claimed in claim 7, wherein said holding means is internal or external to said housing.
9. An apparatus as claimed in any one of claim 1 to claim 7, wherein the computing means is for computing a dose datum indicative of an insulin dose from said total amount of said light that is transmitted; and wherein the apparatus further comprises a blood glucose meter for determining a blood glucose datum indicative of a blood glucose level;
and wherein the recording means is in electrical communication with said computing means and said blood glucose meter, for recording said dose datum and said blood glucose datum.
10. An apparatus as claimed in claim 9, further comprising a port connected to said recording means, for transmitting said dose datum and said blood glucose datum from said recording means to a host computer.
CA2638756A 1996-07-22 1997-07-22 Optical dose measurements in syringes Expired - Fee Related CA2638756C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2638756A CA2638756C (en) 1996-07-22 1997-07-22 Optical dose measurements in syringes

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/681,223 US5792117A (en) 1994-07-22 1996-07-22 Apparatus for optically determining and electronically recording injection doses in syringes
US08/681,223 1996-07-22
CA2638756A CA2638756C (en) 1996-07-22 1997-07-22 Optical dose measurements in syringes
CA002235929A CA2235929C (en) 1996-07-22 1997-07-22 Optical dose measurements in syringes

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002235929A Division CA2235929C (en) 1996-07-22 1997-07-22 Optical dose measurements in syringes

Publications (2)

Publication Number Publication Date
CA2638756A1 true CA2638756A1 (en) 1998-01-29
CA2638756C CA2638756C (en) 2010-09-28

Family

ID=24734336

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2638756A Expired - Fee Related CA2638756C (en) 1996-07-22 1997-07-22 Optical dose measurements in syringes
CA002235929A Expired - Fee Related CA2235929C (en) 1996-07-22 1997-07-22 Optical dose measurements in syringes

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002235929A Expired - Fee Related CA2235929C (en) 1996-07-22 1997-07-22 Optical dose measurements in syringes

Country Status (6)

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US (2) US5792117A (en)
EP (2) EP0858349B1 (en)
AT (1) ATE289831T1 (en)
CA (2) CA2638756C (en)
DE (1) DE69732621T2 (en)
WO (1) WO1998003215A1 (en)

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EP1502614A3 (en) 2007-03-07
ATE289831T1 (en) 2005-03-15
DE69732621T2 (en) 2005-12-29
DE69732621D1 (en) 2005-04-07
CA2638756C (en) 2010-09-28
US5792117A (en) 1998-08-11
WO1998003215A1 (en) 1998-01-29
EP0858349A4 (en) 2000-03-22
EP0858349B1 (en) 2005-03-02
CA2235929A1 (en) 1998-01-29
CA2235929C (en) 2008-12-09
US6113578A (en) 2000-09-05
EP0858349A1 (en) 1998-08-19
EP1502614A2 (en) 2005-02-02

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