CA2672593A1 - Surface modifying macromolecules with high degradation temperatures and uses thereof - Google Patents

Abstract

The invention relates to surface modifying macromolecules (SMMs) having h igh degradation temperatures and their use in the manufacture of articles ma de from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repel lency properties.

Description

SURFACE MODIFYING MACROMOLECULES WITH HIGH
DEGRADATION TEMPERATURES AND USES THEREOF
Cross-Reference to Related Applications This application claims benefit from U.S. Provisional Application No. 60/874,800, filed December 14, 2006, hereby incorporated by reference.
Background of the Invention The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing.

Various fluorochemicals have been used to impart water and oil repellency, as well as soil resistance, to a variety of substrates. These fluorochemicals have most often been applied topically (for example, by spraying, padding, or finish bath immersion). The resulting repellent substrates have found use in numerous applications where water and/or oil repellency (as well as soil resistance) characteristics are valued, such as in protective garments for medical technicians and laboratory workers. The repellent substrates can be used, for example, where it is desirable to prevent passage of blood, blood-borne pathogens, and other body fluids across the fabric (i.e., to block exposure to chemically toxic or infectious agents); and to reduce exposure to low surface tension chemicals, such as alcohols, ketones, and aldehydes.

Medical care garments and protective wear garments used commercially are often fully or partially constructed of extruded articles e.g.
thermoplastic films, thermoplastic fibers, fibrous non-woven materials, thermoplastic foam materials etc. Examples of these products are in surgical drapes, gowns and bandages, protective wear garments (e.g., workers overalls, facemasks, and labcoats, among others). These materials require high temperature processing conditions often exceeding 200 C.

Many fluorochemicals lack the requisite thermal stability to be processed at temperatures above 200 C (for example, in melt spun applications where high extrusion temperatures often exceeding 275-300 C are involved).

Thus, there remains a need for thermally stable additives which can be used in admixture with base polymers that require high temperature processing to impart water and/or oil repellency.

Summary of the Invention The invention provides surface modifying macromolecule (SMM) additives having high degradation temperatures. These SMMs are useful in the manufacture of articles made from base polymers which require high temperature processing.
Accordingly, in a first aspect the invention features a surface modifier of formula (I):

G-[B-A]n-B-G (I) In formula (I), A is a soft segment including hydrogenated polybutadiene, poly (2,2 dimethyl- 1-3-propylcarbonate), polybutadiene, poly (diethylene glycol)adipate, diethylene glycol-ortho phthalic anhydride polyester, or 1,6-hexanediol-ortho phthalic anhydride polyester; B is a hard segment including a urethane; G is a surface active group; and n is an integer from 1 to 10. Surface modifiers of formula (I) can have a thermal degradation temperature of at least 200, 205, 210, 215, 220, 225, 230, 235, 240, 245, 250, 255, 260, 265, 270, 275, 280, 285, 290, 295, 300, 305, 310, 315, 320, 325, 330, 335, 340, 345, 350, or even 355 C. In certain embodiments, the surface modifier has a thermal degradation temperature of between 200 and 345 C, 220 and 345 C, 250 and 345 C, 275 and 345 C, or 300 and 345 C. In other embodiments, the soft segment includes hydrogenated polybutadiene or poly (2,2 dimethyl- 1-3-propylcarbonate). In still other embodiments, the hard segment is 4,4'-methylene bis(cyclohexyl urethane) and n is 1 or 2.

2 In a related aspect the invention features a surface modifier of formula (I):
G-[B-A]õ-B-G (I) In formula (I), A is a soft segment including poly (hexamethylene carbonate), poly (ethylene-co-butylene), 1,6-hexanediol-ortho phthalic anhydride polyester, neopentyl glycol - ortho phthalic anhydride polyester, or bisphenol A ethoxylate; B is a hard segment including a urethane; G is a surface active group; and n is an integer from 1 to 10.

Surface modifiers can be prepared by reacting a diisocyanate (e.g., 3-isocyanatomethyl, 3,5,5- trimethyl cyclohexylisocyanate; 4,4'-methylene bis(cyclohexyl isocyanate); 4,4'-methylene bis(phenyl) isocyanate; toluene-2,4 diisocyanate); m-tetramethylxylene diisocyanate and hexamethylene diisocyanate) with a soft segment diol to form a prepolymer. The prepolymer can then be reacted with monohydroxylic surface active group to form the surface modifier. Desirably, the reactions are performed in the presence of a bismuth carboxylate catalyst.

In certain embodiments, the soft segment has a number average molecular weight, M,,, of 1,000 to 3,500 Daltons.

In still other embodiments, the surface active group has a molecular weight of between 100-1,500 Daltons. Surface active groups include, without limitation, polydimethylsiloxanes, hydrocarbons, polyfluoroalkyl, fluorinated polyethers, and combinations thereof. Desirably, the surface active group is a polyfluoroalkyl, such as 1 H,1 H,2H,2H-perfluoro-l-decanol; 1 H,1 H,2H,2H-perfluoro-l-octanol; 1 H,1 H,5H-perfluoro-l-pentanol; and 1 H,1 H, perfluoro-l-butanol, or mixtures thereof or a radical of the general formulas CF3(CF2),CH2CH2- wherein r is 2-20, and CF3(CF2)S(CH2CH,O)X wherein x is 1-10 and s is 1-20.

In certain embodiments, n is an integer from 1-5. Desirably, n is 1 or 2.

3 The surface modifiers of the invention can have a theoretical molecular weight of less than 25 kDa, desirably less than 20 kDa, 18 kDa, 16 kDa, 15 kDa, 14 kDa, 13 kDa, 12 kDa, 11 kDa, 10 kDa, 8 kDa, 6 kDa, or even 4 kDa.

The surface modifiers of the invention can include from 5% to 35%, 10% to 3 5%, 5 to 30%, lOto30%,5to20%,5to 15 %, or 15 to 30 % (w/w) of the hard segment; from 40 to 90%, 50 to 90%, 60 to 90%, 40 to 80%, or 40 to 70% (w/w) of the soft segment; and from 5 to 40%, 5 to 30%, 5 to 40%, 10 to 40%, 10 to 30%, or 5 to 20%, (w/w) of the surface active group.

The invention also features an admixture including a surface modifier of the invention admixed with a base polymer. In certain embodiments, the base polymer is selected from polypropylenes, polyethylenes, polyesters, polyurethanes, nylons, polysilicones, polystyrene, poly(methyl methacrylates), polyvinylacetates, polycarbonates, poly(acrylonitrile-butadiene), styrene, polyvinylchloride, and blends thereof. For example, SMMs including hydrogenated polybutadiene can be admixed with polypropylenes or polyethylenes, SMMs including poly (2,2 dimethyl- 1-3-propylcarbonate) can be admixed with polyurethanes, and SMMs including poly (ethylene-co-butylene) can be admixed with polyethylenes or polyurethanes.

The admixtures can be prepared by (i) combining the base polymer and the surface modifier to form a mixture, and (ii) heating the mixture above 200 C, 220 C, 250 C, 270 C, or 300 C. The admixtures of the invention contain from 0.05 % to 20 %, 0.05% to 15%, 0.05% to 13%, 0.05% to 10%, 0.05% to 5%, 0.05% to 3%, 0.5% to 15%, 0.5% to 10%, 0.5% to 6%, 0.5% to 4%, 1% to 15%, 1%to 10%, 1%to8%, 1%to6%, 1%to5%,2%to5%,or4%to8%
(w/w) surface modifier.

The invention further features an article formed from an admixture of the invention. Articles that can be formed using the admixtures of the invention include, without limitation, surgical caps, surgical sheets, surgical covering clothes, surgical gowns, masks, gloves, surgical drapes, filter (e.g., part of a respirator, water filter, air filter, or face mask), cables, films, panels, pipes,

4

5 PCT/US2007/025577 fibers, sheets, and implantable medical device (e.g., a cardiac-assist device, a catheter, a stent, a prosthetic implant, an artificial sphincter, or a drug delivery device).

The invention also features a method for making an article by (i) combining a base polymer with a surface modifier of the invention to form a mixture, and (ii) heating the mixture to at least 250 C. Desirably, the mixture is heated to a temperature of between 250 C and 345 C.

The invention further features a method for increasing the thermal degradation temperature of a surface modifier of formula (I):
G-[B-A]n-B-G (I) In formula (I), A is a soft segment; B is a hard segment including a urethane; G is a surface active group; and n is an integer from 1 to 10. The method includes the steps of (a) reacting a diisocyanate with a diol soft segment to form a prepolymer; and (b) reacting the prepolymer with a monohydroxylic surface active group, wherein step (a) or (b) is performed in the presence of a bismuth carboxylate catalyst. In certain embodiments the diol soft segment is selected from hydrogenated-hydroxyl terminated polybutadiene, poly (2,2 dimethyl- 1-3-propylcarbonate) diol, poly (hexamethylene carbonate)diol, poly (ethylene-co-butylene)diol, hydroxyl terminated polybutadiene polyol, poly (diethylene glycol)adipate, poly(tetramethylene oxide) diol, diethylene glycol-ortho phthalic anhydride polyester polyol, 1,6-hexanediol-ortho phthalic anhydride polyester polyol, neopentyl glycol - ortho phthalic anhydride polyester polyol, and bisphenol A ethoxylate diol. In certain embodiments, step (a) includes reacting a diisocyanate with hydrogenated-hydroxyl terminated polybutadiene or poly (2,2 dimethyl- 1-3-propylcarbonate) diol. In other embodiments, the diisocyanate is selected from 3-isocyanatomethyl, 3,5,5-trimethyl cyclohexylisocyanate; 4,4'-methylene bis (cyclohexyl isocyanate);
4,4'-methylene bis (phenyl) isocyanate; toluene-2,4 diisocyanate); and hexamethylene diisocyanate. Monohydroxylic surface active groups useful in making the SMMs of the invention include any disclosed herein. In certain embodiments the monohydroxylic surface active group is selected from compounds of the general formula CF3(CFACH2CH2OH wherein r is 2-20, and CF3(CF2)S(CH2CH2O)xCH2CH2OH wherein x is 1-10 and s is 1-20.

As used herein, "surface modifier" refers to relatively low molecular weight polymers containing a central portion of less than 20 kDa and covalently attached to at least one surface active group. The low molecular weight of the surface modifier allows for diffusion among the macromolecular polymer chains of a base polymer.

By "surface active group" is meant a lipophilic group covalently tethered to a surface modifier. The surface active group can be positioned to cap one or both termini of the central polymeric portion of the surface modifier or can be attached to one or more side chains present in the central polymeric portion of the surface modifier. Examples of surface active groups include, without limitation, polydimethylsiloxanes, hydrocarbons, polyfluoroalkyl, fluorinated polyethers, and combinations thereof.

As used herein, the term "thermal degradation temperature" refers to the temperature at which there is an onset of weight loss (a first onset representing a small weight loss, followed by a second onset at a considerably higher temperature representing the major fraction of the weight) of the SMM during thermographic analysis.

The thermal stability of the SMMs have also been tested under rigorous heating conditions e.g. 220, 260 and 300 C for 10 and 25 minutes and the corresponding weight losses have been determined at these temperatures.
These are typical temperatures experienced by polymers during processing at conditions that require high temperatures. The prolonged heating times of 10 and 25 minutes under isothermal conditions are rather harsh where in reality the polymers would only experience shorter residence time during actual processing (- 1-5 minutes) Additionally, the prolonged heating times are to test the integrity of these surface modified Polymers and gauge the extent of degradation through the weight losses occurring at 10 and 25 minutes. This

6 analysis is described in Example 13.

Other features and advantages of the invention will be apparent from the Drawings, Detailed Description, and the claims.

Brief Description of the Drawing Figure 1 is a graph depicting the High Resolution Thermogravimetric profile of SMM (1) indicating a first onset at a degradation temperature Td, C, representing a minor weight loss (-0.87 %) followed by a major weight loss at Td2 at 405 C (-29.4 %).

Figure 2 is a graph depicting the High Resolution Thermogravimetric profile of SMM (2) indicating a first onset at a degradation temperature Td, C, representing a minor weight loss (-0.79 %) followed by a major weight loss at Td2 of 401 C (-26 %).

Figure 3 is a graph depicting the High Resolution Thermogravimetric profile of SMM (3) indicating a first onset at a degradation temperature Td, C, representing a minor weight loss (-0.82 %) followed by a major weight loss at Td2 of 424 C (-28.4 %).

Figure 4 is a graph depicting the High Resolution Thermogravimetric profile of SMM (4) indicating essentially a single onset at a degradation temperature Td 284 C, which starts off with a small weight loss of 0.62 %
followed immediately by a major weight loss of >90 %.

Figure 5 is a graph depicting the High Resolution Thermogravimetric profile of SMM (5) indicating a first onset at a degradation temperature Td, C, representing a minor weight loss (-2.6 %)followed by a major weight loss at Td2 of 407 C (-31.2 %).

Figure 6 is a graph depicting the High Resolution Thermogravimetric profile of SMM (6) indicating a first onset at a degradation temperature Td, C, representing a minor weight loss (-1.5 %) followed by a major weight loss at Td2 of 374 C (-28.9 %).

7 Figure 7 is a graph depicting the Isothermal Decomposition Profile of SMM (1) when heated at 220 C for 25 minutes under Nitrogen. The profile shows a small weight loss at of 0.27 % after 10 minutes and 0.48 % after 25 minutes isothermal heating.

Figure 8 is a graph depicting the Isothermal Decomposition Profile of SMM (1) when heated at 260 C for 25 minutes under Nitrogen. The profile shows a small weight loss at of 1.38 % after 10 minutes and 4 % after 25 minutes isothermal heating.

Figure 9 is a graph depicting the Isothermal Decomposition Profile of SMM (1) when heated at 300 C for 25 minutes under Nitrogen. The profile shows a 15 % weight loss after 10 minutes and 20 % weight loss after 25 minutes isothermal heating.

Figure 10 is a graph depicting the Isothermal Decomposition Profile of SMM (2) when heated at 220 C for 25 minutes under Nitrogen. The profile shows a small weight loss of 0.46 after 10 minutes and 0.86 % weight loss after 25 minutes isothermal heating.
Figure 11 is a graph depicting the Isothermal Decomposition Profile of SMM (2) when heated at 260 C for 25 minutes under Nitrogen. The profile shows a small weight loss at of 2.35 % after 10 minutes and 7 % after 25 minutes isothermal heating.
Figure 12 is a graph depicting the Isothermal Decomposition Profile of SMM (2) when heated at 300 'C for 25 minutes under Nitrogen. The profile shows a 14 % weight loss after 10 minutes and 20 % weight loss after 25 minutes isothermal heating.

Figure 13 is a series of pictures demonstrating how the surface of the base polymer polyethylene (PE) has been modified by the incorporation of an SMM. This is indicated by the shape and contact angle of a sessile drop of Water and 70 % Isopropanol (IPA) onto the surface modified PE. The varying shape of the drop indicates that there is significant change in the contact angle with the control (unmodified) PE versus PE modified with SMM, both with

8 water and 70 % IPA solutiom: (a) PE control (base polymer) water, (b) PE
modified with 5% SMM(1), (c) PE modified with 5% SMM(2), (d) PE in 70%
isopropanol, (e) PE modified with 5% SMM(1) in 70% isopropanol, and (f) PE
modified with 5% SMM(2) in 70% isopropanol.

Figure 14 is a series of drawings depicting the structures of SMMs (1), (2), (3), and (4a).

Figure 15 is a series of drawings depicting the structures of SMMs (4b), (4c), and (5).

Figure 16 is a series of drawings depicting the structures of SMMs (6), (7), and (8).

Detailed Description The methods and compositions of the invention feature thermally stable SMMs useful for the surface modification of a range of commercially available base polymers which are processed at high temperatures, such as polypropylene, polyethylenes, polyester, nylon 6, polyurethane and silicones, among others.

To provide the required functional properties the SMM additives in this invention are added into the desired base polymer during processing whether it is being extruded, meltspun, spunbond, or injection molded. The additives can impart the following properties: (a) heat and chemical resistance, mechanical strength, (b) oil and water repellency, (b) surface smoothness, (c) resistance to hydrocarbons, acids, polar solvents and bases, (d) dimensional stability at high temperatures, (e) hydrophobic, non-adhesive surface, (f) hydrophilicity characteristics, (g) biocompatibility, (h) reduced thrombogenicity, and/or (i) surface hardness.
Surface modifiers of the invention can be prepared as described in U.S.
Patent No. 6,127,507, incorporated herein by reference, and in Examples 1-8.
Surface modifiers, according to the invention, can be selected in a manner that they contain a soft segment selected to impart thermal stability. Such soft

9 segments include hydrogenated-hydroxyl terminated polybutadiene, poly (2,2 dimethyl-1-3-propylcarbonate) diol, hydroxyl terminated polybutadiene polyol, poly (diethylene glycol)adipate, diethylene glycol-ortho phthalic anhydride polyester polyol, and 1,6-hexanediol-ortho phthalic anhydride polyester polyol.
The invention also includes methods for increasing the thermal stability of an SMM using the synthetic methods described herein to improve their compatibility with the conditions characteristic of base polymer processing techniques. Desirably, the SMMs of the invention are prepared using catalysts that do not include tin, such as bismuth catalysts. It is believed that the presence of very small amounts of tin in the final product can catalyze the degradation of an SMM upon heating, leading to reduced thermal stability. The use of bismuth catalysts in the synthesis of urethanes is well known in the art (see, for example, U.S. Patent Nos. 4,584,362; 4,742,090; 4,788,083;
5,064,871; and 6,353,057). Bismuth catalysts which can be purchased for use in the methods of the invention include Bi348, Bi221, and Bi601 (bismuth carboxylates, King Industries, Norwalk CT), as well as bismuth tris(neodecanoate) (NeoBi 200, Shepherd Chemicals).

The soft segment of the surface modifier can function as an anchor for the surface modifier within the base polymer substrate upon admixture. The surface active groups are responsible, in part, for carrying the surface modifier to the surface of the admixture, where the surface active groups are exposed on the surface. As a result, any loss of surface modifier at the surface of an article of the invention is replenished by the continued migration of surface modifier from the admixture to the surface. The latter process is believed to be driven by tendency towards establishing a low surface energy at the mixture's surface.
When the balance between anchoring and surface migration is achieved, the surface modifier remains stable at the surface of the polymer, while simultaneously altering surface properties.

Suitable base polymers (which can be either thermoplastic or thermoset) include,without limitation, commodity plastics such as poly(vinyl chloride), polyethylenes (high density, low density, very low density), polypropylene, and polystyrene; engineering plastics such as, for example, polyesters (e.g., poly (ethylene terephthalate) and poly (butylene terephthalate)), polyamides (aliphatic, amorphous, aromatic), polycarbonates (e.g., aromatic polycarbonates such as those derived from bisphenol A), polyoxymethylenes, polyacrylates and polymethacrylates (e.g., poly (methyl methacrylate)), some modified polystyrenes (for example, styrene-acrylonitrile (SAN) and acrylonitrile-butadiene-styrene (ABS) copolymers), high-impact polystyrenes (SB), fluoroplastics, and blends such as poly (phenylene oxide)-polystyrene and polycarbonate-ABS; high-performance plastics such as, for example, liquid crystalline polymers (LCPs), polyetherketone (PEEK), polysulfones, polyimides, and polyetherimides; thermosets such as, for example, alkyd resins, phenolic resins, amino resins (e.g., melamine and urea resins), epoxy resins, unsaturated polyesters (including so-called vinyl esters), polyurethanes, allylics (e.g., polymers derived from allyldiglycolcarbonate), fluoroelastomers, and polyacrylates; and blends thereof.
The base polymer is combined with a surface modifier of the invention to form an admixture. Thermoplastic polymers are more preferred in view of their melt processability. The thermoplastic polymers are melt processable at elevated temperatures (e.g., above 200 C, 240 C, 270 'C, or even 300 C).
Desirable thermoset base polymers for use in the admixtures of the invention include, without limitation, polypropylenes, polyethylenes, polyesters, polyurethanes, nylons, polysilicones, polystyrene, poly(methyl methacrylates), polyvinylacetates, polycarbonates, poly(acrylonitrile-butadiene), styrene, polyvinylchloride, and blends thereof.
The surface modifier is added prior to melt processing of the base polymer to produce various articles. To form an admixture by melt processing, the surface modifier can be, for example, mixed with pelletized or powdered polymer and then melt processed by known methods such as, for example, molding, melt blowing, melt spinning, or melt extrusion. The surface modifier can be mixed directly with the polymer in the melt condition or can first be pre-mixed with the polymer in the form of a concentrate of the surface modifier/polymer admixture in a brabender mixer. If desired, an organic solution of the surface modifier can be mixed with powdered or pelletized polymer, followed by evaporation of the solvent and then by melt processing.
Alternatively, the surface modifier can be injected into a molten polymer stream to form an admixture immediately prior to extrusion into fibers, or any other desired shape.

After melt processing, an annealing step can be carried out to enhance the development of repellent characteristics of the base polymer. In addition to, or in lieu of, such an annealing step, the melt processed combination can also be embossed between two heated rolls, one or both of which can be patterned.
An annealing step typically is conducted below the melt temperature of the polymer (e.g., at about 150-220 C for up to 5 minutes in the case of polyamide).

The surface modifier is added to thermoplastic or thermosetting polymer in amounts sufficient to achieve the desired repellency properties for a particular application. Typically, the amount of surface modifier used is in the range of 0.05-15% (w/w) of the admixture. The amounts can be determined empirically and can be adjusted as necessary or desired to achieve the repellency properties without compromising other physical properties of the polymer.

For example, where the base polymer-SMM admixture is processed to produce melt-blowing or melt-spun fibers, these fibers can be used to make non-woven fabrics which have utility in any application where some level of repellency characteristics is desired. For example, the fabrics of the invention can be used for medical fabrics, medical and industrial apparel, fabrics for use in making clothing, home furnishings, and filtration systems, such as chemical process filters or respirators. Other applications are in the automotive and construction industries. The fabrics exhibit alcohol and water repellency characteristics. The fabrics can also exhibit oil repellency (and soil resistance) characteristics under a variety of environmental conditions and can be used in a variety of applications.

Non-woven webs or fabrics can be prepared by processes used in the manufacture of either melt-blowing or spunbonded webs. For example, a process similar to that described by Wente in "Superfine Thermoplastic Fibers,"
Indus. Eng g Chem. 48, 1342 (1956) or by Wente et al. in "Manufacture of Superfine Organic Fibers," Naval Research Laboratories Report No. 4364 (1954) can be used. Multi-layer constructions made from non-woven fabrics enjoy wide industrial and commercial utility, for example, as medical fabrics.
The makeup of the constituent layers of such multi-layer constructions can be varied according to the desired end-use characteristics, and the constructions can comprise two or more layers of melt-blowing and spunbonded webs in many useful combinations such as those described in U.S. Pat. No. 5,145,727 (Potts et al.) and U.S. Pat. No. 5,149,576 (Potts et al.), the descriptions of which are incorporated herein by reference. In multi-layer constructions, the surface modifier can be used in one or more layers to impart repellency characteristics to the overall construction.

Alternatively, the base polymer-SMM admixture is melt processed to produce a desired shape using an appropriate mold.

The following examples are put forth so as to provide those of ordinary skill in the art with a complete disclosure and description of how the methods and compounds claimed herein are performed, made, and evaluated, and are intended to be purely exemplary of the invention and are not intended to limit the scope of what the inventors regard as their invention.

The SMMs of the invention can be constructed by appropriate design combinations of the hard segments (diisocyanates), central soft segments (diols) and the fluorinated end-capping groups to form a wide range of polyurethanes with the desired high degradation temperatures specifically employing Bismuth catalysts in the polymerization. These include, but are not limited to the component reagents mentioned below.

Diisocyanates (hard segments) HMDI = 4,4'-methylene bis(cyclohexyl isocyanate) IPDI = Isophorone Diisocyanate TMXDI = m-tetramethylenexylene Diisocyanate HDI = Hexamethylene Diisocyanate Diols/Polyols (soft segments) HLBH = Hydrogenated-hydroxyl terminated polybutadiene, PCN = Poly (2,2 dimethyl-1-3-propylcarbonate) diol PHCN = Poly (hexamethylene carbonate)diol PEB = Poly (Ethylene-co-Butylene)diol LBHP = Hydroxyl terminated polybutadiene polyol PEGA = Poly (diethylene glycol)adipate PTMO = Poly(tetramethylene Oxide) diol PDP = Diethylene Glycol-Ortho phthalic Anhydride polyester Polyol SPH = 1,6-hexanediol-Ortho Phthalic anhydride polyester polyol SPN = Neopentyl glycol - Ortho Phthalic Anhydride polyester polyol BPAE = Bisphenol A Ethoxylate diol FLUORINATED END-CAPPING GROUPS
C8-FOH = 1 H,1 H,2H,2H Perfluorooctanol C 10-FOH = i H,1 H,2H,2H Perfluorodecanol C8-C 10 FOH = Mixtures of C8- FOH and C 10-FOH
C5-FOH = 1 H, 1 H, 5H, -perfluoro-l-pentanol C4-FOH = 1 H,1 H Perfluorobutanol NON-TIN BASED CATALYST

Bi348 - Bismuth Carboxylate Type 1 Bi221- Bismuth Carboxylate Type 2 Bi601- Bismuth Carboxylate Type 3 The bismuth catalysts listed above can be purchased from King Industries (Norwalk CT). Any bismuth catalyst known in the art can be used to synthesize the SMMs of the invention.

Example 1. General Synthetic Schemes SMMs can be synthesized as shown in Scheme 1. Briefly, a polyol, such as polycarbonate, poly (ethylene-co-butylene) diol, or hydrogenated-hydroxyl terminated polybutadiene, is reacted with a diisocyanate at 65-70 C in an organic solvent (e.g., dimethylacetamide, (DMAc) or toluene) in the presence of a catalyst to form a prepolymer. The ends of the prepolymer are then capped with a perfluorinated alcohol at 45 C. Because the reactions are moisture sensitive, the reactions are carried out under a nitrogen atmosphere under anhydrous conditions. The resulting SMM (if synthesis is performed in DMAC
as solvent) is precipitated by addition of water and washed (e.g., with aqueous IPA/EDTA solutions, followed by IPA/Hexanes) prior to use. If the reaction is performed in toluene the resulting SMM is precipitated by addition of methanol and washed (e.g. THF/EDTA solutions, followed by further precipitations in methanol) prior to use.

Scheme 1 NCO

CHI OCN CH3 OCN-&Cl)&NCO
/ CHH C NCO
TMXDI IPDI NCO HMDI
O
HO \ OH
ozs 0.65 HO'~O O~~OH
oizs H3 C CH3 H3C CH3 LBHP Mo-2000 Catalyst (i) Bismuth Carboxylate Bi348 (ii) Bismuth Carboxylate Bi22I PCN, M,= 1000 Czs (iii) Bismuth Carboxylate Bi601 HO~CH,-CHZH~CH-OH1 Solvent-DMAc, or Toluene HO /~\. LOH
771 xlll y 65-70 "C, N=, ois oe~s `o~.'~~zs PEB, M. - 2500 3 h HLBH M. - 2000 II II
oCN R,- i ' c~o-R-O~c~i-RI NCO
H
H
HMDI, IPDI, TMXDI = R, ------------------------------R = PEB, PCN,HLBH, LBHP------------------------- R, = HMDI, IPDI, TMXDI
Urethane Pre-Polymer CF,-(CFZ)sCHzCHZOH (C8-FOH) I or CHF=(CF=)3 CH2 OH (C5-FOH) I or CF3-(CF2)2 CH2 OH (C4-FOH) I + Bismuth Catalyst, 45 C, 18 h (C8-FOH) or---------------- HMDI, IPDI, TMXDI---------------PEB, PCN, HLBH, LBHP-- -----HMDI , IPDI, TMXDI-----(C8-FOH or (C5-FOH) or (C4FOH) (C5-FOH) or (C4-FOH) Z

Example 2. Synthesis of SMM (1) All glassware used for the synthesis was dried in an oven at 110 C
overnight. To a 3- necked 1000 ml oven dried flask equipped with a stir bar was added 175 g (72 mmol) of Hydrogenated-hydroxyl terminated polybutadiene (HLBH polyol, MW = 2000). The flask with the polyol was degassed overnight and then purged with dry N2. A 1000 mL graduated cylinder was filled with 525 mL anhydrous Toluene, sealed by a rubber septa and purged with dry N2. The toluene was transferred to the 3-necked flask via a double-edged needle and the polyol stirred vigorously to dissolve in the solvent.
The flask was placed in an oil bath at 65-70 C. 39.70 g (151 mmol) of 4,4'-methylene bis (cyclohexyl isocyanate) (HMDI) was added to a degassed 250 ml flask equipped with a stir bar. To this flask was added 150 ml of anhydrous toluene from a degassed, NZ purged 250 ml septa-sealed cylinder also using a double-edged needle and the mixture was stirred to dissolve the HMDI in the solvent. To a degassed 50 ml round bottom flask was added 8.75 g (5.00 %
w/w based on diol) of the bismuth carboxylate catalyst followed by 26 ml of toluene to dissolve the catalyst. The HMDI solution was transferred to the 1000 ml flask containing the polyol. The bismuth catalyst solution was added (20 ml) immediately following the addition of the HMDI. The reaction mixture was allowed to stir for 5 h at 70 C to produce a HMDI-HLBH prepolymer.
In another 50 ml round bottom flask 74.95 g (180 mmol) of C8-C 10 FOH (mixture of C8-FOH and C 10-FOH) was added, capped with a septa, degassed and then purged with N2. This was added to the 1000 ml flask containing prepolymer. All additions and transfers were conducted carefully in an atmosphere of dry N2 to avoid any contact with air. The resulting mixture was heated to 45 C for 18 hours to produce SMM (1) with the end-capped C8-C 10 FOH. The SMM solution was allowed to cool to ambient temperature and formed a milky solution. The milky solution was precipitated in MeOH
(methanol) and the resulting precipitate was washed repeatedly with MeOH to form a white viscous material with dough-like consistency. This viscous, semi-solid material was washed twice in THF/EDTA (Ethylene Diamine Tetraacetic Acid) to remove residual catalyst followed by two more successive washes in THF/MeOH to remove unreacted monomers, low molecular weight byproducts, and catalyst residues. The SMM was first dried in a flow oven from at 40-120 C in a period of 10 hours gradually raising the temperature and finally dried under vacuum at 120 C (24 hours) and stored in a desiccator as a colorless rubbery semi-solid. The chemical structure of the SMM (1) is shown Figure 14.

Example 3. Synthesis of SMM(2) The reaction was carried out as described in Example 2 using 180 g (74 mmol) Hydrogenated-hydroxyl terminated polybutadiene (HLBH polyol, MW =
2000) and 30.14 g (115 mmol) of 4,4'-methylene bis(cyclohexyl isocyanate) (HMDI) to form the prepolymer. The prepolymer was end-capped with 40.48 g (111.18 mmol) of 1 H, 1 H, 2H, 2H-perfluoro-l-octanol (C8-FOH ) to form SMM (2) as a colorless rubbery semi-solid. As described above, the couplings were carried out in the presence of bismuth carboxylate catalyst and the SMM
was washed similarly to SMM (1) and dried prior to use. The chemical structure of the SMM (2) is shown in Figure 14.

Example 4. Synthesis of SMM (3) The reaction was carried out as described in Example 3 using 10 g (4 mmol) poly (ethylene-co-butylene (PEB polyol, MW = 2500) and 2.20 g (8.4 mmol) of 4,4'-methylene bis(cyclohexyl isocyanate) (HMDI) to form the prepolymer. The prepolymer was capped with 3.64 g (10 mmol) of 1 H, 1 H, 2H, 2H-perfluoro-l-octanol (C8-FOH) to form SMM (3). As described above, the couplings were carried out in the presence of bismuth carboxylate catalyst and the SMM was washed similarly to SMM (1) and dried prior to use. The chemical structure of the SMM (3) is shown in Figure 14.

Example 5. Synthesis of SMM (4a) The reaction was carried out as described in Example 4, except the solvent was changed from toluene to DMAC. Here, 100 g (100 mmol) poly (2,2 dimethyl-1,3-propylcarbonate) diol (PCN, MW 1000) and 40.7 g (155 mmol) of 4,4'-methylene bis (cyclohexyl isocyanate) (HMDI) to form the prepolymer. The prepolymer was end-capped with 45.5 g (125 mmol) of 1 H, 1 H, 2H, 2H-perfluoro-l-octanol (C8-FOH) to form SMM (4a). The work-up after the reaction and the subsequent washing procedures are modified from Example 4 as follows. The SMM from the reaction mixture in DMAC was precipitated in distilled water, and washed successively in IPA/EDTA
(Isopropanol/Ethylene Diamine Tetraacetic Acid) solution followed by another wash in IPA/hexanes to remove unreacted monomers, low molecular weight byproducts and catalyst residues to yield SMM (4a) as a white amorphous powder. As described above, the couplings were carried out in the presence of bismuth carboxylate catalyst and dried under vacuum prior to use. The chemical structure of the SMM (4a) is shown in Figure 14.

Example 6. Synthesis of SMM (4b) The reaction was carried out as described in Example 5 using 6.0 g (6.0 mmol) poly (2,2 dimethyl- 1,3-propylcarbonate) diol (MW 1000) and 1.90 g (8.5 mmol) of isophorone diisocyanate (IPDI) to form the prepolymer. The prepolymer was end-capped with 1.4 g (6.0 mmol) of 1 H, 1 H, 5H, -perfluoro-l-pentanol (C5-FOH) to form SMM (3) as a white amorphous solid. As described above, the couplings were carried out in the presence of bismuth carboxylate catalyst and the SMM was washed similar to SMM (4a) and dried prior to use. The chemical structure of the SMM (4b) is shown in Figure 15.

Example 7. Synthesis of SMM (4c) The reaction was carried out as described in Example 5 using 10.0 g (10.0 mmol) poly (2,2 dimethyl-1,3-propylcarbonate) diol (MW 1000) and 4.07 g (15.5 mmol) of 4,4'-methylene bis (cyclohexyl isocyanate) (HMDI) to form the prepolymer. The prepolymer was capped with 2.5 g (12.5 mmol) of 1 H, 1 H-Perfluoro-l-butanol (C4-FOH) to form SMM 4c as a white amorphous solid. As described above, the couplings were carried out in the presence of bismuth carboxylate catalyst and the SMM was washed similar to SMM (4a) and dried prior to use. The chemical structure of the SMM (4c) is shown in Figure 15.

Example 8. Synthesis of SMM(5) The reaction was carried out as described in Example 5 using 180 g (84.8 mmol) Hydroxyl terminated polybutadiene (LBHP polyol, MW = 2000) and 29.21 g (131.42 mmol) of isophorone diisocyanate (IPDI) to form the prepolymer. The prepolymer was capped with 46.31 g (127.18 mmol) of 1 H, 1 H, 2H, 2H-perfluoro-l-octanol (C8-FOH) to form SMM (5) as a off-white opaque viscous liquid. As described above, the couplings were camed out in the presence of bismuth carboxylate catalyst and the SMM was washed similarly to SMM (4a) and dried prior to use. The chemical structure of the SMM (5) is shown in Figure 15.

Example 9. Synthesis of SMM(6) The reaction was carried out as described in Example 5 using 10 g (3.92 mmol) Poly (diethyhlene glycol adipate) (PEGA polyol, MW = 2500) and 1.59 g (6.08 mmol) of 4,4'-methylene bis(cyclohexyl isocyanate) (HMDI) to form the prepolymer. The prepolymer was capped with 2.14 g(5.88 mmol) of 1H, 1 H, 2H, 2H-perfluoro-l-octanol (C8-FOH) to form SMM (6) as a off-white opaque viscous liquid. As described above, the couplings were carried out in the presence of bismuth carboxylate catalyst and the SMM was washed similarly to SMM (4a) and dried prior to use. The chemical structure of the SMM (6) is shown in Figure 16.

Example 10. Synthesis of SMM(7) The reaction was carried out as described in Example 5 using 10 g (5.06 mmol), Ortho phthalate-diethylene glycol based Polyester polyol (PDP polyol, MW = 2000) and 1.92 g (7.85 mmol) of m-tetramethylenexylene Diisocyanate (TMXDI) to form the prepolymer. The prepolymer was capped with 2.76 g (7.59 mmol) of 1 H, 1 H, 2H, 2H-perfluoro-l-octanol (C8-FOH) to form SMM
(7) as a colorless solid. As described above, the couplings were carried out in the presence of bismuth carboxylate catalyst and the SMM was washed similarly to SMM (4a) and dried prior to use. The chemical structure of SMM
(7) is shown in Figure 16.

Example 11. Synthesis of SMM (8) SMM (8), which includes a Poly (tetramethylene oxide), PTMO soft segment, has a degradation temperature of only 229 C and is included for comparison. The SMM(8) material can be synthesized as described in U.S.
Patent No. 6,127,507. Both the prepolymer coupling and surface active group coupling were performed using dibutyl tin dilaurate as a catalyst.

Example 12. Synthesis of SMM (9) The theoretical structure of SMM (9) is identical to that of SMM (8).
The SMM (9) material is synthesized using the methods of Example 5. Both the prepolymer coupling and surface active group coupling were performed using a Bi carboxylate catalyst to yield SMM (9) as a white amorphous solid.
Example 13. Thermal Stability The thermal degradation temperatures of the surface modifying macromolecules (SMM) were determined by a Thermogravimetric Analysis instrument (TGA). Thermogravimetric analysis (TGA) is often used to determine thermal stability by means of weight-loss decomposition profiles as a function of temperature. This was carried out using a TA instruments TGA
Q500 (V6.3 Build 189 with autosampler) Thermogravimetric Analyzer operating in Dynamic (High Resolution), Hi-ResTm mode <resolution: 4, max ramp: 50 C/min, max temp: 500 C.

Briefly, 20-50 mg of each sample was placed into 100 L platinum plans (part no. 952018.906) suspended from an analytical balance located outside the furnace chamber. After the balance was zeroed, the sample pan was heated from ambient to 500 C in a Nitrogen atmosphere, N2 (flow rate 40cc/min balance, 60cc/min. furnace). The Hi-Res TGA mode varies the heating rate as a function of sample weight loss rate, which allows the use of high heating rates during no weight loss regions and reduced heating rates at weight loss transitions to more accurately depict the decomposition characteristics of the test sample. This technique improves the reproducibility and resolution of onsets by separating overlapping or poorly defined events and it eliminates the dependence of decomposition behavior on the heating rate. A TGA plot indicating the weight loss and the rate of weight loss (or derivative) was plotted against the temperature using the Universal Analysis 2000 software (TA
Instruments - Waters LLC, version 4.1 D). If the material is completely dry, upon heating there is an onset (one or two depending upon the nature of the polymer) representing the start of degradation. As an illustrative example, Figure 1 shows a High Resolution Thermogravimetric profile of SMM (1) indicating a first onset at a degradation temperature Tdl 326 C representing a minor weight loss (-0.87 %) due to the hard segment (isocyanate linkage), followed by a major weight loss (-29.41%) at Td2 of 405 C due to the soft segment (polyol linkage) of the SMM's.

Figures 1 -6 show the thermal degradation pattern of various examples of SMMs (1-6) depicted by a High Resolution Thermogravimetric Plot. The thermal data including TGA and DSC results are summarized in Table 1 below.

Example 14. Differential Scanning Calorimerty Differential Scanning Calorimetry (DSC) was used to identify other thermal transitions of the SMM's, such as the glass transition temperature (Tg), of the amorphous phase or the melting points of the crystalline phases of the SMM's. The analysis was carried out using a TA Instruments Q 100 (V9.6 Build 290) Differential Scanning Calorimeter (DSC) with a TA Instruments Refrigerated Cooling System (RCS-90; 970008.902) and autosampler (part no.971000.901). The analysis was performed under nitrogen with a flow rate of 50 cc/min.

Briefly, 2-10 mg of each sample were accurately weighed and hermetically sealed into aluminum pans (part no. 900793.901) with aluminum lids (900794.90 1). A second sealed empty pan was used as a reference. Both pans were placed on a thermoelectric disc that transfers heat to the pans from a controlled heating block. The temperature of the heating block was raised or lowered in a linear manner and the resulting differential heat flow to the sample and reference pans was monitored by a thermocouple.

For the first heating-cooling run the samples were heated from -90 C to 150 C, cooled back down to -90 C. This was followed by a second heating-cooling run from -90 C to 150 C. The heating and cooling rates were set at10 C/min. Several heating and cooling scans (usually 2 or 3) were performed in this fashion to eliminate any artifacts associated with thermal history. The thermal transitions were identified by a change in heat capacity with temperature which is then plotted as a DSC plot. The DSC scans were analyzed with the Universal Analysis 2000 software (TA Instruments - Waters LLC, version 4.1 D). Thermal transitions such as glass transition temperatures and melting points were calculated with the software for both the first and second heating, but only the data from the second heating was recorded.

The thermal transitions are related to the state of the hard and soft segments in the polymer chain. The Tg is indicative of the transition from a stiff glassy state to an amorphous state where the mobility of the polymer backbone increases and is identified as a baseline shift in the DSC scan. The values in Table 1 for the Tg shows the behavior of the soft segment as it responds to a change in temperature.

Table 1. TGA and DSC Analysis of EndexoTM SMM's SMM Wt % Wt % Wt % MWb TGA`, `C Tg Appearance Hard Soft FTa Tdld Td2e (% wt loss) (% wt loss) 1 13.9 64.6 22 3785 326 406 -44 Colorless, Rubbery (-0.9) (-29.4) semi-solid 2 12.4 76.2 11.4 6372 319 401 -46 Colorless, Rubbery (-0.8) (-26) semi-solid 3 14.0 66.6 19.4 3753 220 424 26 Waxy off-white (-0.8) (-28) solid 4a 22.4 56.9 20.7 3515 284 288 28 White amorphous (-0.5) (- >75) solid 4b 21.3 63.9 14.8 3131 270 337 10 White chunky solid (-1) (-99) 4c 24.7 62.8 12.6 3187 272 341 28 White amorphous (-4) (-40) solid 11.8 75.3 12.9 5641 283 407 -46 colorless viscous (-2.6) (-31.2) liquid 6 11.9 77.1 11.0 6617 311 374 -38 colorless viscous (-1.9) (-29) liquid 7 13.5 73 13.5 5411 263 363 19 colorless solid (-0.9) (-29) 8 16.3 48.5 35.3 2065 229 353 -75 White amorphous (-1.3) (-57) solid 9 16.3 48.5 35.3 2065 276 407 30 White amorphous (-2) (65) solid a % F end-capping groups b Theoretical Molecular Weight in Daltons.
` High Resolution Thermographic Analysis under N2 5 d Degradation Temperature Tdi C, from the first onset, represents the hard segment, ` Degradation Td2 C of the soft segment, from the second onset.
f Glass Transition Temperature ( C) in a Differential Scanning Calorimeter after second heat.

As shown in Table 1, a large increase in thermal stability may be achieved by choosing the appropriate soft segment or diol unit. For example, use of a soft segment selected from a polyolefinic group, such as polybutadiene, hydrogenated polybutadienes or poly (ethylene-co-butylene) (SMM's 1, 2, 3, 5), or polycarbonate polyol (SMM's 4a, 4b, 4c), poly(diethylene glycol) adipate or ortho phthalate-diethylene glycol polyester polyol (SMM's 6, 7) can increase the thermal stability of the SMM. This is quite evident by comparing the thermal degradation temperatures of SMM's (1-7) with SMM's 8 and 9 which are based on polyether polyols only. For example, comparing the TGA data of SMM (1) and (2) vs SMM (8) the Tdl of SMM (1) and SMM (2) are 326 and 319 C which is considerable higher than SMM (8) with a Tdi = 229 C.

Furthermore, a significant increase in stability is observed for materials coupled using bismuth carboxylate catalyst rather than dibutyl tin dilaurate (i.e., compare SMM (8), Tdl = 229 C to SMM (9), Td] = 276 C). A further advantage in working with bismuth catalyst is that it is non-toxic and environmentally friendly compared to tin catalysts. It is believed that Bismuth catalysts are more selective in its reactivity and avoid potential side reactions with isocyanate leading to urea linkages in the presence of trace amounts of water. These side reactions can disrupt symmetry in the main-chain of the SMM, affecting thermal properties, such as Td and Tg.

Example 15. CarbothaneT", Polyethylene (PE) and Polypropylene (PP) -SMM Admixtures Solution cast films were made from three different base polymers that are widely used in industry. These are CarbothaneTM (Shore hardness 85 A), polyethylene (PE) and polypropylene (PP). The base polymers were admixed with selective SMM's in 4-5 % (w/w) in the appropriate solvent to give a range of admixtures. For example, Carbothane was admixed with SMM 3, 4a, or 8 in DMAC solvent and films were cast on TeflonTM or Aluminum substrates. In another instance PE was admixed with SMM's 1, 2, 3, 4a, 5, or 8 in cholorobenzene solvent and films were cast on glass substrate. Finally, PP was admixed with SMM 1 and 2 in chlorobenzene solvent and films formed on glass substrates.

Example 16. Surface Elemental Analysis by X-Ray Photoelectron Spectroscopy (XPS) CarbothaneTM (Thermedics Inc MA, USA), PE and PP were used as control polymer and the base polymer -SMM admixtures of Example 15 were analyzed by XPS to determine the concentration of surface fluorine (hydrophobic) as well as the Urethane chemistries (polar groups). The measurements were performed at a single take-off angle of 90 corresponding to a depth of 100 A and analyzed using a surface area of 4 x 7 mm2 -sufficiently representative of the film being analyzed - which was bombarded with the X-Rays. The films were investigated for relative atomic percentages of Fluorine (F), Oxygen (0), Nitrogen, Carbon (C) and Silicon. Only the results of atomic % of Fluorine (F), the element of interest, for 3 different base polymers used as control as well as modified with SMM's are provided as illustrations in Table 2.

Example 17. Contact Angle Measurements Contact angle is a useful measure of the surface properties of materials (e.g. to measure relative wettability). Carbothanel"4 (Thermedics Inc MA, USA), PE and PP were used as control polymer and the base polymer -SMM
admixtures of Example 15 were analyzed. The advancing and receding contact angle of water and advancing contact angle of 70% isopropanol solution on the films were measured using a Kruss Drop Shape Analysis system (DSA 100).
Solutions were injected with a 500 1 Syringe (part no. SY20) and a 0.5mm diameter, 25mm length needle (part no. NE13). Images were captured using the built in digital camera connected to a computer and processed using the Kruss Drop Shape Analysis DSA 1 software.

Sample preparation Films were cut into 1 cm by 5cm strips and mounted at the edges of glass slides with double-sided tape. All mounted samples were dried at room temperature under vacuum overnight prior to analysis.

Drop Parameters:
Drop size: 20 l Drop rate: 30 gl/sec Drop Type: sessile drop Advancing and receding angles were measured by capturing the instantaneous advancing and receding images of the solution drop. The advancing contact angle was taken after injecting 20 l onto the surface of the film, keeping the needle inside the bubble. After an additional 20 l was injected into the bubble, 20 l was retracted from the bubble and the receding angle was taken immediately. The images were processed with Kruss Drop Shape Analysis DSA 1 software and the contact angles on both sides of the drop was measured using "Tangent method 2", which determines the slope of the three-phase contact point at the manually selected baseline. If the surfaces are hydrophilic the liquid is attracted towards the surface and so the angles will be low. Similarly for hydrophobic surfaces the liquid will try to make minimum contact with the surface and so the contact angles will be high. Subsequently, receding angles are also measured by partially withdrawing the water droplet.
In many cases there is a distinct difference between the Advancing and Receding angles called the contact angle hysteresis. This is a measure of the surface topography (smooth or rough surface), chemical heterogeneity and changes in chemistry. The results of the advancing angles in both water and 70% IPA solutions with the same base polymers as mentioned in Example 16 are also provided in Table 2. Six measurements were taken and on each side of the drop and these were averaged.

Table 2. XPS and Contact Angle Analysis of SMM-modified CarbothaneTm, PP, and PE Films Analysis Base SMM (1) SMM (2) SMM (3) SMM (4a) SMM (5) SMM (8) Polymer 0% 4-5% 0% 4-5% 0% 4-5% 0% 4-5% 0% 4-5% 0% 4-5%
Pua ---- ---- ---- ---- 0 20 0 24 ---- ---- 0 40 XPS -Surface F PEb 0 18 0 20 0 44 0 24 0 8 0 38 (atm %) PP` 0 21 0 21 ---- ---- ---- ---- ---- ---- ---- ----Contact Angle PE 108 125 108 123 108 119 108 122 108 116 108 115 Advancing in Water Contact Angle Advancing in PE 43 75 43 64 43 82 43 75 43 75 43 75 70 % IPA
Solution e PU = A conunercial Polyurethane e.g. CarbothaneTM (Thermedics Inc MA, USA).
b PE = A commercial Polyethylene ` PP = A commercial Polypropylene In each example, the admixtures of SMM with base polymer exhibit a substantial amount of surface fluorine (see XPS data comparing 0% SMM to 4-5% SMM formulations), which in turn increases both the water and alcohol repellency of the SMM admixtures (see the (see the contact angle data in water and alcohol comparing 0% SMM to 4-5% SMM formulations).

In contrast, when SMM (8) (Tdi = 229 C, see Table 1) was admixed with PE in at 4 % with compounding in an extruder at 220 C, substantial degradation of the SMM was observed (evidenced by evolution of fumes and condensed liquid). The resulting admixture exhibited reduced surface fluorine content and reduced water and alcohol repellency in comparison to admixtures formed without degradation.

Example 18. Data for additional SMMs Other SMMs were prepared using the methods described above. The thermal degradation properties of these SMMs are summarized below in Table 3.

Table 3: SMM Hard, Soft, Fluoro end groups Segments and Degradation Temperatures Soft Segment-MW Hard Segment Fluoro End Groups TGA C (N2)e Polyol (%) Diisocyanate(%) (%) Tdi Td2 HLBH-2000 (64.6) HMDI (13.9) C8-C10 FOH (22) 326 406 HLBH-2000 (66.0) HMDI (14.3) C8-FOH (19.8) 312 402 HLBH-2000 ( 77.7) IPDI (10.7) C8-FOH (11.6) 302 ----HLBH-3000 (83.0) IPDI (8.1) C8-FOH (8.9) 270 ----HLBH-2000 (76.2) HMDI (12.4) C8-FOH (11.4) 319 401 HLBH-2000 (76.9) TMXDI (11.6) C8-FOH (11.5) 337 ----HLBH-2000 (80.4) HMDI (11.6) C8-FOH (8.0) 321 397 PCN-1000 (56.9) HMDI (22.4) C8-FOH (20.7) 284 288 PCN-1000 (57.8) TMXDI (21.2) C8-FOH (21.0) 275 296 PCN-1000 (63.9) IPDI (21.3) C5-FOH (14.8) 270 337 PCN-1000 (62.8) HMDI (24.7) C4-FOH (12.6) 272 341 PHCN-2000 (72.5) HMDI (14.3) C8-FOH (13.2) 247 300 PHCN-2000 (73.2) TMXDI (13.4) C8-FOH (13.3) 204 308 PEB-2500 (66.6) HMDI (14.0) C8-FOH (19.4) 220 424 PEB-2500 (67.3) TMXDI (13.1) C8-FOH (19.6) 201 408 LBHP-2000 (75.3) IPDI (11.8) C8-FOH (12.9) 283 407 LBHP-2000 (74.4) TMXDI (12.8) C8-FOH (12.8) 231 407 LBHP-2000 (64.4) IPDI (13.5) C8-FOH (22.1) 210 404 LBHP-2000 (79.7) IPDI (11.1) C8-FOH (9.1) 233 404 LBH-2000 (74.3) IPDI (12.3) C8-FOH (13.4) 248 435 PEGA-2000 (78.5) IPDI (10.3) C8-FOH (11.2) 241 364 PEGA-2000 (77.1) HMDI (11.9) C8-FOH (11.0) 311 374 PEGA-2000 (77.7) TMXDI (11.2) C8-FOH (11.1) 246 350 PDP-2000 (73.9) IPDI (12.5) C8-FOH (13.6) 270 340 PDP-2000 (72.3) HMDI (14.4) C8-FOH (13.3) 230 340 PDP-2000 (73.0) TMXDI (13.5) C8-FOH (13.5) 263 363 SPN -1000 (57.7) HMDI (22.0) C8-FOH (20.3) 206 309 SPH-2000 (72.7) HMDI (14.2) C8-FOH (13.1) 257 334 BPAE-1000 (39.4) HMDI (31.5) C8-FOH (29.1) 229 318 Other Embodiments All publications, patents, and patent applications mentioned in this specification are herein incorporated by reference to the same extent as if each independent publication or patent application was specifically and individually indicated to be incorporated by reference.

While the invention has been described in connection with specific embodiments thereof, it will be understood that it is capable of further modifications and this application is intended to cover any variations, uses, or adaptations of the invention following, in general, the principles of the invention and including such departures from the present disclosure that come within known or customary practice within the art to which the invention pertains and may be applied to the essential features hereinbefore set forth, and follows in the scope of the claims.

Other embodiments are within the claims.
What is claimed is:

Claims (39)

Claims

1. A surface modifier of formula (I):
G-[B-A]n-B-G (I) wherein (i) A is a soft segment comprising hydrogenated polybutadiene, poly (2,2 dimethyl-1-3-propylcarbonate), polybutadiene, poly (diethylene glycol)adipate, diethylene glycol-ortho phthalic anhydride polyester, or 1,6-hexanediol-ortho phthalic anhydride polyester;

(ii) B is a hard segment comprising a urethane; and (iii) G is a surface active group, wherein n is an integer from 1 to 10 and said surface modifier has a thermal degradation temperature of between 250 °C and 345 °C.

2. The surface modifier of claim 1, wherein said surface modifier has a thermal degradation temperature of between 300 °C and 345 °C.

3. The surface modifier of claim 1, wherein said soft segment comprises hydrogenated polybutadiene or poly (2,2 dimethyl-1-3-propylcarbonate).

4. The surface modifier of claim 3, wherein said 4,4'-methylene bis(cyclohexyl urethane) and n is 1 or 2.

5. A surface modifier of formula (I):
G-[B-A]n-B-G (I) wherein (i) A is a soft segment comprising poly (hexamethylene carbonate), poly (ethylene-co-butylene), 1,6-hexanediol-ortho phthalic anhydride polyester, neopentyl glycol - ortho phthalic anhydride polyester, or bisphenol A

ethoxylate;
(ii) B is a hard segment comprising a urethane; and (iii) G is a surface active group, wherein n is an integer from 1 to 10.

6. The surface modifier of claim 1 or 5, wherein said surface modifier is formed by a process that comprises the step of reacting a diisocyanate with a diol comprising said soft segment to form a prepolymer.

7. The surface modifier of claim 6, wherein said diol is selected from poly(2-butyl-2-ethyl-1,3-propyl carbonate) diol; poly(2,2 dimethyl-1-3-propyl carbonate) diol; and poly(hexamethylene carbonate)diol.

8. The surface modifier of claim 6, wherein said diisocyanate is selected from 3-isocyanatomethyl, 3,5,5-trimethyl cyclohexylisocyanate; 4,4'-methylene bis(cyclohexyl isocyanate); 4,4'-methylene bis(phenyl) isocyanate;
toluene-2,4 diisocyanate); m-tetramethylxylene diisocyanate; and hexamethylene diisocyanate.

9. The surface modifier of any of claims 6, 7, or 8, wherein said step of reacting is performed in the presence of a bismuth carboxylate catalyst.

10. The surface modifier of claim 6, wherein said surface modifier is formed by a process that further comprises the step of reacting said prepolymer with a monohydroxylic surface active group.

11. The surface modifier of any of claim 10, wherein said step of reacting said prepolymer with said monohydroxylic surface active group is performed in the presence of a bismuth carboxylate catalyst.

12. The surface modifier of claim 1 or 5, wherein said soft segment has a number average molecular weight, Mn, of 1,000 to 3,500 Daltons.

13. The surface modifier of claim 1 or 5, wherein G has a molecular weight of between 100-1,500 Da.

14. The surface modifier of claim 13, wherein said surface active group is selected from polydimethylsiloxanes, hydrocarbons, polyfluoroalkyl, fluorinated polyethers, and combinations thereof.

15. The surface modifier of claim 14, wherein said surface active group is a polyfluoroalkyl.

16. The surface modifier of claim 15, wherein said surface active group is selected from 1H,1H,2H,2H-perfluoro-1-decanol; 1H,1H,2H,2H-perfluoro-1-octanol; 1H,1H,5H-perfluoro-1-pentanol; and 1H,1H, perfluoro-1-butanol, and mixtures thereof.

17. The surface modifier of claim 15, wherein said surface active group is selected from the group consisting of radicals of the general formula CF3(CF2)r CH2CH2 - wherein r is 2-20, and CF3(CF2)s(CH2CH2O).chi. wherein .chi. is 1-10 and s is 1-20.

18. The surface modifier of claim 1 or 5, wherein n is 1.

19. The surface modifier of claim 1 or 5, wherein n is 2.

20. The surface modifier of claim 1 or 5, wherein said surface modifier has a theoretical molecular weight of less than 10,000 Daltons.

21. The surface modifier of claim 1 or 5, wherein said surface modifier comprises from 5 to 30 % (w/w) of said hard segment, from 40 to 90 % (w/w) of said soft segment, and from 5 to 40 % (w/w) of said surface active group.

22. An admixture comprising a surface modifier of any of claims 1-20 admixed with a base polymer.

23. The admixture of claim 22, wherein said base polymer is selected from polypropylenes, polyethylenes, polyesters, polyurethanes, nylons, polysilicones, polystyrene, poly(methyl methacrylates), polyvinylacetates, polycarbonates, poly(acrylonitrile-butadiene), styrene, polyvinylchloride, and blends thereof.

24. The admixture of claim 22, formed by (i) combining said base polymer and said surface modifier to form a mixture, and (ii) heating said mixture above 200 °C.

25. The admixture of claim 22, wherein said admixture comprises from 0.05% to 10% (w/w) of said surface modifier.

26. An article formed from an admixture of any of claims 22-25.

27. The article of claim 26, wherein said article is selected from surgical caps, surgical sheets, surgical covering clothes, surgical gowns, masks, gloves, and surgical drapes.

28. The article of claim 26, wherein said article is a filter.

29. The article of claim 28, wherein said filter is part of a respirator, water filter, air filter, or face mask.

30. The article of claim 26, wherein said article is a cable, film, panel, pipe, fiber, or sheet.

31. The article of claim 26, wherein said article is an implantable medical device.

32. The article of claim 31, wherein said article is a cardiac-assist device, a catheter, a stent, a prosthetic implant, an artificial sphincter, or a drug delivery device.

33. A method for making an article, said method comprising the steps of (i) combining a base polymer with a surface modifier of any of claims 1-20 to form a mixture, and (ii) heating said mixture to at least 200 °C.

34. The method of claim 33, wherein step (ii) comprises heating said mixture to a temperature of between 250 °C and 345 °C.

35. A method for increasing the thermal degradation temperature of a surface modifier of formula (I):

G - [B - A]n-B-G (I) wherein (i) A is a soft segment;

(ii) B is a hard segment comprising a urethane;
(iii) G is a surface active group; and (iv) n is an integer from 1 to 10, said method comprising the steps of:

(a) reacting a diisocyanate with a diol soft segment to form a prepolymer; and (b) reacting said prepolymer with a monohydroxylic surface active group, wherein step (a) or (b) is performed in the presence of a bismuth carboxylate catalyst.

36. The method of claim 35, wherein said diol soft segment is selected from hydrogenated-hydroxyl terminated polybutadiene, poly (2,2 dimethyl- 1-3-propylcarbonate) diol, poly (hexamethylene carbonate)diol, poly (ethylene-co-butylene)diol, hydroxyl terminated polybutadiene polyol, poly (diethylene glycol)adipate, poly(tetramethylene oxide) diol, diethylene glycol-ortho phthalic anhydride polyester polyol, 1,6-hexanediol-ortho phthalic anhydride polyester polyol, neopentyl glycol - ortho phthalic anhydride polyester polyol, and bisphenol A ethoxylate diol.

37. The method of claim 35, wherein step (a) comprises reacting a diisocyanate with hydrogenated-hydroxyl terminated polybutadiene or poly (2,2 dimethyl-1-3-propylcarbonate) diol.

38. The method of claim 35, wherein said diisocyanate is selected from 3-isocyanatomethyl, 3,5,5-trimethyl cyclohexylisocyanate; 4,4'-methylene bis(cyclohexyl isocyanate); 4,4'-methylene bis(phenyl) isocyanate; toluene-2,4 diisocyanate); m-tetramethylxylene diisocyanate; and hexamethylene diisocyanate.

39. The method of claim 35, wherein said monohydroxylic surface active group is selected from compounds of the general formula CF3(CF2)r CH2CH2OH wherein r is 2-20, and CF3(CF2)s(CH2CH2O).chi.CH2CH2OH wherein .chi. is 1-10 and s is 1-20.