CN100401989C - System for obtaining and processing nystagmography of rat dizzy - Google Patents

System for obtaining and processing nystagmography of rat dizzy Download PDF

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Publication number
CN100401989C
CN100401989C CNB2006101050821A CN200610105082A CN100401989C CN 100401989 C CN100401989 C CN 100401989C CN B2006101050821 A CNB2006101050821 A CN B2006101050821A CN 200610105082 A CN200610105082 A CN 200610105082A CN 100401989 C CN100401989 C CN 100401989C
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China
Prior art keywords
rat
ball
basket
dizzy
video camera
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Expired - Fee Related
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CNB2006101050821A
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Chinese (zh)
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CN1911178A (en
Inventor
史仪凯
邓梁
袁小庆
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Northwestern Polytechnical University
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Northwestern Polytechnical University
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Priority to CNB2006101050821A priority Critical patent/CN100401989C/en
Publication of CN1911178A publication Critical patent/CN1911178A/en
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Abstract

A system for acquiring and processing the nystagmus signals of rat in rotational dizziness state in order to analyze the cause of dizziness and evaluating the curative effect of medicine to dizziness is composed of a horizontal motor, an arc arm fixed to output shaft of said motor, a spherical cage with upper and lower supporting rods connected to both ends of said arc arm, a rat bed in the horizontal center of said spherical cage, a camera installed on said rat bed, and a signal receiving and processing device connected to said camera in wireless mode.

Description

Nystagmography of rat dizzy obtains and processing system
Technical field
The present invention relates to the nystagmus signal and obtain and processing system, particularly nystagmography of rat dizzy obtains and processing system.
Background technology
The article introduction of document " Chinese country doctor's magazine; 2003; 10 (3) " Chen Xuetao, dizzy is the clinical common diseases phenomenon, medical statistics show dizzy have 80 surplus kind of a cause of disease cause, the dizzy nystagmus symptom that often is mixed with, each is variant for the characteristics of different its nystagmus of the dizzy cause of disease, clinical diagnosis technology the feature of nystagmus as analyzing the dizzy cause of disease, the signal of nystagmus obtains with its feature of Accurate Analysis has the important clinical meaning, curative effect according to the pharmacological experimental technique checking medicine dizzy with estimating treatment is normally made dizzy model with rat, give treatment dizzy medicine then, the evaluation of drug action and experimental technique need obtain the signal of nystagmus, but do not report as yet that so far the signal that this system is used for the pharmacological experiment of vertigo medicine obtains and processing system.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of nystagmography of rat dizzy and obtains and processing system.
The technical solution adopted for the present invention to solve the technical problems is: a kind of nystagmography of rat dizzy obtains and processing system, comprise base 7, support shaft 5, vertical type motor 1, horizontal motor 6 and video camera 9, it is characterized in that: comprise that also arc arm 2, ball-type change basket 4, rat platform 10 for sleeping in and signal receiving and processing device, horizontal motor 6 is fixed on the support shaft 5 by axle sleeve, arc arm 2 is fixed on the output shaft of horizontal motor 6, and arc arm 2 is done vertical rotation with horizontal motor 6; The south poles that ball-type changes basket 4 is fixed with lower carriage 8 and upper bracket 3 respectively, and is connected the two ends up and down of arc arm 2 by minor axis on the last lower carriage and bearing, and ball-type changes basket 4 and horizontally rotates with vertical type motor 1; Ball-type changes the horizontal center of basket 4 rat platform 10 for sleeping in is installed, and level is installed video camera 9 on the rat platform 10 for sleeping in, and the camera lens and the rat of video camera 9 are in opposite directions visual; Signal receiving and processing device and video camera 9 wireless connections.
The invention has the beneficial effects as follows, adopt vertical type motor and horizontal motor to drive ball-type and change the rotation that basket is made two degree of freedom, make rat dizzy, obtain the nystagmus signal by video camera, after the wireless receiving blood processor is gathered and is handled, for the dizzy cause of disease of clinical analysis of diagnosis, also can be used as the dizzy model of rat of the pharmacological experiment method validation curative effect of medication dizzy with estimating treatment, estimate treatment dizzy medicine, drug effect.
The invention will be further described below in conjunction with drawings and Examples.
Description of drawings
Fig. 1 is that nystagmography of rat dizzy of the present invention obtains and the processing system sketch map.
Fig. 2 is the signal receiving and processing device circuit diagram among Fig. 1.
1-vertical type motor 2-arc arm 3-upper bracket 4-ball-type changes basket 5-support shaft 6-horizontal motor 7-base 8-lower carriage 9-video camera 10-rat Wo Tai
The specific embodiment
With reference to Fig. 1, Fig. 2, the present invention is achieved in that nystagmography of rat dizzy obtains system and causes dizzy platform by motion, rat nystagmus signal acquisition system, and the nystagmus signal wireless transmission system, signals collecting and signal processing system are formed.
Rat motor causes dizzy platform, by base 7 supporting bracket axles 5, support shaft 5 is installed horizontal motor 6, horizontal motor 6 output shafts are installed arc arm 2, vertical arc arm 2 two-end-points by center of arc are installed ball-type is changeed basket 4, and the south poles end points that ball-type changes basket 4 is connected with the two-end-point of arc arm 2 by two minor axises respectively, and ball-type changes the arctic end points of basket 4 vertical type motor 1 is installed, ball-type changes the horizontal center of basket 4 rat platform 10 for sleeping in is installed, and with the visual direction of rat video camera 9 is installed.
Motion causes dizzy experimental implementation flow process according to the following steps: the first step is fixed on the horizontal platform of rat with rat, visual direction of rat and video camera are in opposite directions, second step started horizontal motor, the horizontal motor rotation drives the arc arm rotation, the arc arm rotation drives ball-type changes the basket rotation, being fixed on ball-type changes rat on the horizontal center rat Wo Tai of basket and changes the basket rotation with ball-type and do the long axis direction rotation, it is the rotation of rat rocking motion, frequency and time increase rat with rotation produce dizzy symptom, absorb the nystagmus signal that the built-in wireless transmission circuit synchronized transmissions of video camera video camera obtains with synchronous nystagmus quilt that produces of the dizzy symptom of rat and the video camera of installing in opposite directions.In order further to analyze the relation that motion posture and rat produce dizzy symptom, the another kind posture that rotatablely moves is, start ball-type and change the vertical type motor that basket arctic end points is installed, vertical type motor drives ball-type commentaries on classics basket and makes horizontal rotation, being fixed on ball-type changes rat on the horizontal center rat Wo Tai of basket and changes basket with ball-type and horizontally rotate and do centrifugal rotation, be that the rat health is done the circular arc rotation, frequency and time increase rat with rotation produce dizzy symptom, with dizzy symptom nystagmus quilt that produces synchronously and the video camera picked-up of installing in opposite directions of rat, the nystagmus signal that video camera series connection wireless transmission circuit synchronized transmissions video camera obtains.
Nystagmus signal wireless transfer system:
Wireless transmission system is made up of monolithic radio frequency chip nRF2401, microcontroller MSP430F1121, serial line interface 8250 and interface chip 75LV4737, adopt standard RS232C interface to carry out serial communication between wireless module and PC, the PCB antenna that goes in ring is adopted in communication between wireless module.
Signals collecting and signal processing system:
Microcontroller MSP430F1121 has 16 risc architectures, 16 bit CPU depositor and literal registers, 4KBROM, 256B Flash, 256B RAM, instruction cycletime 125ns, running voltage 1.8~3.6V, power consumption 1.3~160 μ A have 5 kinds of battery saving modes, the serializable online programming.
Ball-type changes upper bracket 3 that basket 4 arctic ends install and vertical type motor 1 by the arc arm 2 end points ball-type that links and changes basket 4 South Pole ends lower carriages 8 are installed, horizontal motor 6 output shafts of the support shaft 5 on supporting arc arm 2 central points that ball-type changes basket 4 and being fixed on base 7 connect, ball-type changes the horizontal center of basket 4 rat platform 10 for sleeping in is installed, platform Plane Installation video camera 9 crouches, video camera 9 is equipped with sender unit, and its camera lens and rat are in opposite directions visual.The sphere that ball-type changes basket 4 is the aluminium alloy network.
The wireless host transceiver module mainly is made up of monolithic radio frequency chip nRF2401, microcontroller MSP430F1121, serial line interface 8250 and interface chip 75LV4737, adopt standard RS232C interface to carry out serial communication between wireless module and PC, the PCB antenna that goes in ring is adopted in communication between wireless module.Microcontroller is the control centre of whole module, finishes the setting of nRF2401 mode of operation, receives and handles the data that receiving circuit received of nRF2401, and pass to serial line interface; The radiating circuit of control nRF2401 will send from the data of serial line interface, and level conversion and the data of being finished the RS232C interface of microcontroller MSP430F1121 and PC by interface chip 75LV4737 send, receive, ask, remove function.
The nRF2401 transceiver adopts 0.18 μ m CMOS technology manufacturing, and with the QFN24 5 * 5mm of 24 feet encapsulation, operating frequency is 2.4~2.5GHz, adopts the GFSK modulation and demodulation, and capacity of resisting disturbance is strong, can receive two channels simultaneously.Maximum current when receiving mode is less than 15mA, and the maximum current during sending mode is 8mA.NRF2401 has 79 basic passages and 49 additional channels.It has the ShockBurst characteristic, uses FIFO on the sheet, allow microcontroller with the low data rate record data, and the RF transceiver can very high rate sending data.This characteristic reduces power consumption and reaches 95%, can keep 10kbps continuous link speed.
When chip uses, at first use DLL CFG-CLK, CFG-DATA, the CS of chip, parameters such as setting, setting operating frequency, passage, output and output clock frequency that internal register is programmed by microcontroller.After entering normal operating conditions, receive/send out conversion and control as required, transmission/reception data or carry out state conversion by microcontroller.

Claims (3)

1. a nystagmography of rat dizzy obtains and processing system, comprise base (7), support shaft (5), vertical type motor (1), horizontal motor (6) and video camera (9), it is characterized in that: comprise that also arc arm (2), ball-type change basket (4), rat Wo Tai (10) and signal receiving and processing device, horizontal motor (6) is fixed on the support shaft (5) by axle sleeve, arc arm (2) is fixed on the output shaft of horizontal motor (6), and arc arm (2) is done vertically rotation with horizontal motor (6); The south poles that ball-type changes basket (4) is fixed with lower carriage (8) and upper bracket (3) respectively, and is connected the two ends up and down of arc arm (2) by minor axis on the last lower carriage and bearing, and ball-type commentaries on classics basket (4) horizontally rotates with vertical type motor (1); Ball-type changes the horizontal center of basket (4) rat Wo Tai (10) is installed, and rat Wo Tai (10) goes up level video camera (9) is installed, and the camera lens and the rat of video camera (9) are in opposite directions visual; Signal receiving and processing device and video camera (9) wireless connections.
2. nystagmography of rat dizzy according to claim 1 obtains and processing system, it is characterized in that: described video camera (9) is equipped with sender unit.
3. nystagmography of rat dizzy according to claim 1 obtains and processing system, it is characterized in that: the sphere that described ball-type changes basket (4) is the aluminium alloy network.
CNB2006101050821A 2006-09-01 2006-09-01 System for obtaining and processing nystagmography of rat dizzy Expired - Fee Related CN100401989C (en)

Priority Applications (1)

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CNB2006101050821A CN100401989C (en) 2006-09-01 2006-09-01 System for obtaining and processing nystagmography of rat dizzy

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Application Number Priority Date Filing Date Title
CNB2006101050821A CN100401989C (en) 2006-09-01 2006-09-01 System for obtaining and processing nystagmography of rat dizzy

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CN1911178A CN1911178A (en) 2007-02-14
CN100401989C true CN100401989C (en) 2008-07-16

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2044884U (en) * 1988-12-07 1989-09-27 张子斌 Apparatus for training human body rotating in three dimensions
CN2207208Y (en) * 1994-10-19 1995-09-13 马春东 Globe game machine
US20040006287A1 (en) * 2002-07-03 2004-01-08 Epley John M. Comprehensive vertigo management
US20040097839A1 (en) * 2002-07-03 2004-05-20 Epley Research, L.L.C. Head-stabilized medical apparatus, system and methodology

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2044884U (en) * 1988-12-07 1989-09-27 张子斌 Apparatus for training human body rotating in three dimensions
CN2207208Y (en) * 1994-10-19 1995-09-13 马春东 Globe game machine
US20040006287A1 (en) * 2002-07-03 2004-01-08 Epley John M. Comprehensive vertigo management
US20040097839A1 (en) * 2002-07-03 2004-05-20 Epley Research, L.L.C. Head-stabilized medical apparatus, system and methodology

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Granted publication date: 20080716

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