CN101389264A - 集成疾病诊断和治疗系统 - Google Patents
集成疾病诊断和治疗系统 Download PDFInfo
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Abstract
Description
假设的肿瘤直径 | 1cm | ||
大概的肿瘤体积 | 0.5cc | ||
传递的光功率 | 0.5瓦 | 1.0瓦 | 2.0瓦 |
估计的激光功率 | 1.5瓦 | 3.0瓦 | 6.0瓦 |
温升 | |||
5秒钟曝光 | +5℃ | +10℃ | +20℃ |
10秒钟曝光 | +10℃ | +20℃ | +40℃ |
Claims (31)
- 要求保护的是正文中描述的和附图中所示出的,包括:
- 1.一种医疗设备,包括:气管镜,包括工作管道,配置用于插入到身体的通道中以到达身体内部的目标区域;光纤探测模块,包括(1)具有插入到气管镜的工作管道中的部分的探测光纤,以及(2)光学探头,与探测光纤的一端相连,并且位于所述工作管道的内部,所述光纤探测设备可操作用于通过探测光纤和光学探头将探测光定向到身体中的目标区域,并且收集来自目标区域的反射光,并且用于进一步地从所收集的反射光获得目标区域的信息;以及激光治疗模块,包括功率传递光纤,具有插入到气管镜的工作管道中以向目标区域传递治疗激光束的部分。
- 2.根据权利要求1实施的设备,还包括:计算断层(CT)模块,用于扫描身体的至少一部分,以获得身体的扫描部分的CT扫描数据,该CT扫描数据被分析用于标识和定位恶性可疑目标区域,用于通过光纤探测模块进一步地探测和分析。
- 3.根据权利要求1所述的设备,其中,构建所述探测光纤以支持处于第一传播模式和不同的第二传播模式的光,并且光纤探测模块还包括:光源,用于产生探测光,其中所述探测光纤接收和引导处于第一传播模式的探测光;其中,光纤探头与探测光纤相连以从探测光纤接收光,并且以第一传播模式将所述光的第一部分反射回探测光纤中,并且将所述光的第二部分定向到目标区域,所述探头收集从目标区域的第二部分的反射,并且向探测光纤输出所述反射作为处于第二传播模式的反射第二部分;光学差分延迟单元,用于响应于控制信号,产生和控制从探测光纤接收到的所反射第一部分和所反射的第二部分之间的相对延迟;检测模块,用于从探测光纤接收所反射的第一部分和所反射的第二部分,并且提取由所反射的第二部分所携带的目标区域的信息;以及控制单元,向光学差分延迟单元产生控制信号,用于以两个不同偏置值设置相对延迟,以选择目标区域内部的材料层,以测量选定层的光学吸收。
- 4.根据权利要求3所述的设备,其中,检测模块包括:光学设备,用于将按照第一传播模式的光沿第一光路进行定向,以及将按照第二传播模式的光沿不同的第二光路进行定向;第一光学元件,处于第一光路中以将不同波段处的光分离为第一组不同的光束;多个第一光检测器,用于分别接收和检测来自第一光学元件的第一组不同的光束;第二光学元件,处于第二光路中以将不同波段处的光分离为第二组不同的光束;以及多个第二光检测器,用于分别接收和检测来自第二光学元件的第二组不同的光束。
- 5.根据权利要求4所述的设备,其中,第一和第二光学元件是光栅。
- 6.根据权利要求3所述的设备,其中,检测模块包括数字信号处理器,用于处理所反射的第二部分中的目标区域的信息,并且用于产生目标区域的光谱吸收数据。
- 7.根据权利要求3所述的设备,其中,光学差分延迟单元包括:模式分离单元,用于将接收到的光分为按照第一传播模式的第一光束和按照第二传播模式的第二光束;以及在第一和第二光束之一中的可变光学延迟元件,用于响应于控制信号调节第一和第二光束之间的光学延迟。
- 8.根据权利要求3所述的设备,其中,第一和第二传播模式是由探测光纤支持的两个正交偏振模式,并且其中检测模块包括:光检测器;以及光偏振器,用于接收和混合所反射的第一和第二部分,以向光检测器产生光学输出。
- 9.根据权利要求3所述的设备,其中,光学探头包括部分模式转换器,将来自目标的反射设定于第二传播模式。
- 10.根据权利要求3所述的设备,其中,光学探头包括:部分反射器,用于反射探测光的所反射的第一部分,并且用于向样品传输探测光的第二部分;以及偏振旋转器,位于部分反射器和目标区域之间,用于改变所反射的第二部分的偏振,来控制所反射的第二部分处于第二传播模式。
- 11.根据权利要求3所述的设备,其中,光学探头包括:部分反射器,用于反射探测光的所反射的第一部分,并且用于向目标区域传输探测光的第二部分;以及法拉第旋转器,位于部分反射器和目标区域之间,用于改变所反射的第二部分的偏振,来控制所反射的第二部分处于第二传播模式。
- 12.根据权利要求3所述的设备,其中,光学探头包括:部分反射器,用于反射探测光的所反射的第一部分,并且用于向目标区域传输探测光的第二部分;以及四分之一波片,位于部分反射器和目标之间,用于改变所反射的第二部分的偏振,来控制所反射的第二部分处于第二传播模式。
- 13.根据权利要求3所述的设备,其中,光纤探测模块还包括:输入波导,用于从光源接收探测光,并且用于引导处于第一传播模式的输入光束;输出波导,用于从探测光纤接收所反射的第一部分和第二部分,并且用于将所反射的第一和第二部分定向到光学差分延迟单元;以及光路由器,与输入波导、探测光纤和输出波导相连,所述光路由器将来自输入波导的光定向到探测光纤,并且将来自探测光纤的管定向到输出波导。
- 14.根据权利要求13所述的设备,其中,光学路由器包括:光学环行器;第一分束器,处于探测光纤中,用于传输处于第一传播模式的光,并且用于反射处于第二传播模式的光;第二分束器,处于输出波导中,用于传输处于第一传播模式的光,并且用于反射处于第二传播模式的光;以及旁路波导,连接在第一和第二分束器之间,用于将由第一分束器反射的所反射第二部分定向到第二分束器,所述第二分束器通过反射将所反射的第二部分定向到输出波导中。
- 15.根据权利要求13所述的设备,还包括:可调光学滤波器,位于输入波导之一中;探测光纤;以及输出波导,用于选择目标区域的光谱响应的一部分来进行测量。
- 16.根据权利要求1所述的设备,还包括可调光学滤波器,用于对探测光进行滤波,以选择目标区域的光谱响应的一部分来进行测量。
- 17.根据权利要求1所述的设备,还包括可调光学滤波器,用于对所反射的第一和第二部分进行滤波,以选择目标区域的光谱响应的一部分来进行测量。
- 18.根据权利要求1所述的设备,其中,光纤探测模块还包括:多个光源,将以不同波长为中心的不同波段的光作为探测光发射到探测光纤中,其中,光学探头以第一传播模式将探测光的第一部分反射回探测光纤中,并且将探测光的第二部分定向到目标区域,以及探头收集来自目标区域的第二部分的反射,并且向探测光纤输出所述反射作为处于与第一传播模式不同的第二传播模式的所反射的第二部分;光学差分延迟单元,用于响应于控制信号,产生和控制从单波导接收到的所反射的第一部分和所反射的第二部分之间的相对延迟;检测模块,用于接收所反射的第一部分和所反射的第二部分,并且用于提取由所反射的第二部分携带的目标区域的信息;以及探测控制单元,向光学差分延迟单元产生控制信号,用于以两个不同偏置值设置相对延迟,以选择目标区域内部的材料层,以测量来自不同光源的每一个波长处的选定层的光吸收。
- 19.根据权利要求1所述的设备,其中,光纤探测模块还包括:多个可调激光源,将以不同波长为中心的不同波段内的光作为探测光发射到探测光纤中,其中所述探测光纤配置用于接收和引导处于第一传播模式的不同波段的探测光;其中,光学探头用于以第一传播模式将探测光的第一部分反射回探测光纤中,并且将光的第二部分定向到目标区域,以及探头收集来自目标区域的第二部分的反射,并且向探测光纤输出所述反射作为处于与第一传播模式不同的第二传播模式的所反射的第二部分;检测模块,用于在波导中接收所反射的第一部分和所反射的第二部分,并且用于提取由所反射的第二部分携带的目标区域的信息;以及探测控制单元,用于对相应激光发射波段中的每一个可调激光器进行调谐,以获得每一个相应波段之内的不同波长处目标区域的吸收测量值。
- 20.根据权利要求1所述的设备,还包括:管状单元,用于保持探测光纤、探头和功率传递光纤作为插入到气管镜的工作通道中的单独组件。
- 21.一种用于肺癌治疗的医疗设备,包括:计算断层(CT)扫描单元,用于检测和定位肺的肺部节结位置;光学剖面成像单元,用于光学地测量和分析每一个肺部节结位置,以在良性和恶性肺部节结位置之间进行区分;以及放射治疗单元,用于光学治疗恶性的选定肺部节结位置。
- 22.根据权利要求21所述的设备,其中,放射治疗单元包括微波切除治疗单元,用于治疗选定的肺部节结位置。
- 23.根据权利要求22所述的设备,还包括内窥镜,所述内窥镜包括工作管道,其中,光学截面成像单元包括探测光纤,用于向每一个肺部节结位置传递探测光以光学地测量每一个位置,以及工作通道内部的一部分探测光纤,以传递探测光。
- 24.一种集成诊断和治疗系统,包括:CT扫描单元,用于定位身体部分中的病区;基准剖面成像单元,用于分析每一个病区;以及激光放射治疗单元,用于治疗选定的病区。
- 25.根据权利要求24所述的系统,其中,每一个病区均受到前列腺癌的感染。
- 26.根据权利要求24所述的系统,其中,每一个病区均是肺的一部分,并且受到肺癌的感染。
- 27.根据权利要求24所述的系统,其中,每一个病区均受到与前列腺癌和肺癌不同的癌症的感染。
- 28.一种用于诊断和治疗患者的恶性疾病的方法,包括:在患者的选定身体部分中执行计算断层(CT)扫描,以标识选定身体部分中潜在恶性位置;使用光探测束以光学地探测所标识的位置,以进一步地将恶性位置与良性位置相标识;以及向每一个所标识的恶性位置传递辐射能量,以治疗恶性疾病。
- 29.根据权利要求28所述的方法,其中,辐射能量从微波或RF源获得。
- 30.根据权利要求28所述的方法,其中,辐射源从激光获得。
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Also Published As
Publication number | Publication date |
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WO2006045013A3 (en) | 2007-11-29 |
CN101389264B (zh) | 2011-07-27 |
EP1804661B1 (en) | 2014-06-11 |
WO2006045013A2 (en) | 2006-04-27 |
EP1804661A4 (en) | 2010-12-22 |
US7970458B2 (en) | 2011-06-28 |
US20060079762A1 (en) | 2006-04-13 |
EP1804661A2 (en) | 2007-07-11 |
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