CN102331423A - Feces occult blood test paper and preparation method thereof - Google Patents

Feces occult blood test paper and preparation method thereof Download PDF

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Publication number
CN102331423A
CN102331423A CN201110277510A CN201110277510A CN102331423A CN 102331423 A CN102331423 A CN 102331423A CN 201110277510 A CN201110277510 A CN 201110277510A CN 201110277510 A CN201110277510 A CN 201110277510A CN 102331423 A CN102331423 A CN 102331423A
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CN
China
Prior art keywords
test paper
color layer
occult blood
paper body
detection
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Pending
Application number
CN201110277510A
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Chinese (zh)
Inventor
孔艳
张晓阳
孙若亮
王海兵
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SUZHOU HAOOUBO BIOPHARMACEUTICAL CO Ltd
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SUZHOU HAOOUBO BIOPHARMACEUTICAL CO Ltd
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Priority to CN201110277510A priority Critical patent/CN102331423A/en
Publication of CN102331423A publication Critical patent/CN102331423A/en
Pending legal-status Critical Current

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Abstract

The invention relates to feces occult blood test paper and a preparation method thereof. The feces occult blood test paper comprises a test paper body and is characterized by further comprising a color developing layer and latex, wherein the color developing layer is formed on the test paper body and can have color change in the presence of hemoglobin, the latex is arranged on the test paper body and used for sealing the periphery of the color developing layer. The feces occult blood test paper is adopted for testing without professional testing people, and is very simple to operate, sanitary and environmentally-friendly; and the result can be fast obtained.

Description

Just occult blood and detect test paper and preparation method thereof
Technical field
the present invention relates to a kind of detection test paper and preparation method thereof, particularly a kind of detection test paper of just occulting blood.
Background technology
The detection method that just occult blood the earliest is a chemical staining method, and 1864, Van Deen at first used guaiac glue and detects as indicant and just occult blood.Afterwards; There are chemical staining methods such as benzidine method, phenolphthalin method, adjacent benzidine method, pyramidon method, colourless peacock green method, tetramethyl benzidine method to propose just to occult blood detection again; The ultimate principle of these chemical staining methods is consistent; Just contain haemocyte in occulting blood and digested the haemoglobin that the back produces, haemoglobin has the porphyrin structure, has similar activity with peroxidase.Superoxide can be produced nascent oxygen by catalysis under the situation that has haemoglobin to exist; Nascent oxygen is very active; Oxidability is very strong; Can make Guaiacolate, biphenylamine, phenolphthalein, o-tolidine, pyramidon, the former material colour generation of colourless peacock green and tetramethyl benzidine isochrome, whether the result can judge to contain in the ight soil and occult blood according to colour developing.
are just occulted blood and detect the chemical staining method that uses at present;, collection ight soil also need use at least a other detectable except that being applied on the detection test paper (or test card) in the operating process; Could accomplish detection as damping fluid (dilution ight soil) or demonstration liquid (containing superoxide) or the liquid (containing chromogenic reagent) that develops the color etc. are auxiliary; Method of operating is more loaded down with trivial details, and detects the potential problems that employed reagent bottle etc. has contaminated environment.
Summary of the invention
technical matters to be solved by this invention is the deficiency that overcomes prior art, and a kind of detection test paper of just occulting blood is provided, and uses the detection of just occulting blood of this detection test paper, not only simply but also hygienic environment-protecting.
the present invention also will provide a kind of above-mentioned just occulting blood to detect the preparation method of test paper simultaneously, and its technology is simple, and cost is low.
For solving above technical matters, a kind of technical scheme that the present invention takes is:
a kind of detection test paper of just occulting blood; It comprises the test paper body; Particularly, it also comprises and is formed on the test paper body, the color layer of change color can take place in the presence of haemoglobin and is arranged on the latex that is used on the test paper body the sealing of the periphery of color layer.
according to a preferred aspect of the present invention, said test paper body is square.Described color layer is the cruciform that is positioned at test paper body middle part.
said color layer can be to constitute by being selected from the following material one or more: Guaiacolate, biphenylamine, phenolphthalein, o-tolidine, pyramidon, colourless peacock green, tetramethyl benzidine and superoxide.Preferably, said color layer is made up of tetramethyl benzidine and superoxide.
The another technical scheme that the present invention takes is: a kind of above-mentioned just occulting blood detects the preparation method of test paper; This method forms said color layer through said material to the haemoglobin colour developing is applied or is printed on the said test paper body, the periphery at color layer seals with latex then.
Because the enforcement of above technical scheme, the present invention compared with prior art has following advantage:
detection test paper provided by the invention only needs it is lost into urinal, and the change color of observing color layer can obtain testing result; Need not use loading auxiliary reagents such as reagent bottle; Reduce consumption of raw materials, reduced cost, can not cause environmental pollution.When detecting in addition, need not gather ight soil and dilution ight soil, not need to drip other liquid such as developer or peroxide solutions on the test paper yet toward detecting, simple to operate, convenient and healthy.
The preparation method that the present invention detects test paper adopts coating or printing type to form, and technology is simple, and cost is lower.
Description of drawings
Below in conjunction with accompanying drawing and concrete embodiment, the present invention is done further detailed explanation:
Fig. 1 is for detecting the structural representation of test paper according to of the present invention just occulting blood;
wherein: 1, test paper body; 2, color layer; 3, latex.
Embodiment
are as shown in Figure 1; Detecting test paper according to just occulting blood of present embodiment comprises square test paper body 1, is formed on criss-cross color layer 2 of being of test paper body 1 middle part (this color layer is made up of tetramethyl benzidine and superoxide, can through applying or mode such as printing is formed on the test paper body) and be used for the color layer 2 peripheral latexes 3 that seal.
Just the occulting blood of this example detected test paper and is preferably in airtight, room temperature, Shi Du< 45% environment is preserved down.The cross district is colourless, if the condition of preserving is bad, such as being exposed in the air, can become very light faint yellow or yellow green, but this can not have influence on the detection performance of product.
Whether this detection test paper of just occulting blood can be detected by patient oneself, specifically is, greatly after an action of the bowels, will detect test paper and be dropped in the urinal, observe the cross district and have or not color reaction just can know to suffer from just to occult blood.As long as obvious change color takes place any position in the cross zone, then explain to contain in the ight soil and occult blood; Otherwise, there is not change color if detect test paper, explain then not contain in the ight soil and occult blood that detection finishes, closet flushing washes away test paper and gets final product.
are compared with the existing detection method of just occulting blood, and when taking detection test paper of the present invention to detect, need not professional testing staff and carry out, operate very simple, hygienic environment-protecting, and can obtain the result fast.
The foregoing description only is explanation technical conceive of the present invention and characteristics; Its purpose is to let the personage who is familiar with this technology can understand content of the present invention and enforcement according to this; Can not limit protection scope of the present invention with this; All equivalences that spirit is done according to the present invention change or modify, and all should be encompassed within protection scope of the present invention

Claims (6)

1. detection test paper of just occulting blood; Comprise test paper body (1), it is characterized in that: said just occult blood detect test paper also comprise be formed on said test paper body (1) go up, at the color layer (2) that change color can take place in the presence of the haemoglobin and be arranged on and be used for the latex (3) that the periphery with said color layer (2) seals on the test paper body (1).
2. the detection test paper of just occulting blood according to claim 1 is characterized in that: said test paper body (1) is for square.
3. the detection test paper of just occulting blood according to claim 1 and 2 is characterized in that: described color layer (2) is for being positioned at the cruciform in the middle part of the said test paper body (1).
4. detection test paper according to claim 1; It is characterized in that: said color layer (2) constitutes by being selected from the following material one or more: Guaiacolate, biphenylamine, phenolphthalein, o-tolidine, pyramidon, colourless peacock green, tetramethyl benzidine and superoxide.
5. detection test paper according to claim 4 is characterized in that: described color layer (2) is made up of tetramethyl benzidine and superoxide.
6. described just the occulting blood of each claim detected the preparation method of test paper in the claim 1 to 5; It is characterized in that: this method goes up formation said color layer (2) through said material to the haemoglobin colour developing is applied or be printed on said test paper body (1), and the periphery at color layer (2) seals with latex then.
CN201110277510A 2011-09-19 2011-09-19 Feces occult blood test paper and preparation method thereof Pending CN102331423A (en)

Priority Applications (1)

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CN201110277510A CN102331423A (en) 2011-09-19 2011-09-19 Feces occult blood test paper and preparation method thereof

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CN102331423A true CN102331423A (en) 2012-01-25

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103969193A (en) * 2013-01-28 2014-08-06 郑兆珉 sperm quality detection device
CN106039467A (en) * 2016-07-13 2016-10-26 上海市儿童医院 Multi-purpose protection device for indwelling needle infusion connector
CN106323966A (en) * 2016-10-31 2017-01-11 百奥森(江苏)食品安全科技有限公司 Detection paper for disinfector residue and preparation method thereof
CN107505315A (en) * 2017-09-27 2017-12-22 安徽朗德生物科技有限公司 A kind of stool blood kit and application method
CN107764814A (en) * 2017-09-27 2018-03-06 安徽朗德生物科技有限公司 A kind of fecal occult blood test test paper coating process flow
CN108680573A (en) * 2018-08-27 2018-10-19 陈继贵 Sequential excrement is occulted blood acquisition testing integrated device
CN109444122A (en) * 2018-10-26 2019-03-08 南通大学 A kind of Test paper
CN109444122B (en) * 2018-10-26 2024-04-12 南通大学 Test paper

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57190266A (en) * 1981-05-01 1982-11-22 Smith Kline Instr Slide for improved test body test and occult test method using said slide
US5081040A (en) * 1987-06-29 1992-01-14 Helena Laboratories Corporation Composition and kit for testing for occult blood in human and animal excretions, fluids, or tissue matrixes
WO2003098224A1 (en) * 2002-05-14 2003-11-27 Ottfried Waldenburg Device for & method of testing occult blood in feces
CN2849725Y (en) * 2005-05-27 2006-12-20 万志静 Kit for testing occult blood
CN101614673A (en) * 2009-07-21 2009-12-30 北京智云达科技有限公司 Test paper of nitrite and preparation method thereof in a kind of fast detecting food
CN202230025U (en) * 2011-09-19 2012-05-23 苏州浩欧博生物医药有限公司 Feces occult blood detection test paper

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57190266A (en) * 1981-05-01 1982-11-22 Smith Kline Instr Slide for improved test body test and occult test method using said slide
US5081040A (en) * 1987-06-29 1992-01-14 Helena Laboratories Corporation Composition and kit for testing for occult blood in human and animal excretions, fluids, or tissue matrixes
WO2003098224A1 (en) * 2002-05-14 2003-11-27 Ottfried Waldenburg Device for & method of testing occult blood in feces
CN2849725Y (en) * 2005-05-27 2006-12-20 万志静 Kit for testing occult blood
CN101614673A (en) * 2009-07-21 2009-12-30 北京智云达科技有限公司 Test paper of nitrite and preparation method thereof in a kind of fast detecting food
CN202230025U (en) * 2011-09-19 2012-05-23 苏州浩欧博生物医药有限公司 Feces occult blood detection test paper

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Title
姜燕: "便潜血一步法检测试纸临床研究", 《实用临床医学》 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103969193A (en) * 2013-01-28 2014-08-06 郑兆珉 sperm quality detection device
CN106039467A (en) * 2016-07-13 2016-10-26 上海市儿童医院 Multi-purpose protection device for indwelling needle infusion connector
CN106323966A (en) * 2016-10-31 2017-01-11 百奥森(江苏)食品安全科技有限公司 Detection paper for disinfector residue and preparation method thereof
CN107505315A (en) * 2017-09-27 2017-12-22 安徽朗德生物科技有限公司 A kind of stool blood kit and application method
CN107764814A (en) * 2017-09-27 2018-03-06 安徽朗德生物科技有限公司 A kind of fecal occult blood test test paper coating process flow
CN108680573A (en) * 2018-08-27 2018-10-19 陈继贵 Sequential excrement is occulted blood acquisition testing integrated device
CN108680573B (en) * 2018-08-27 2023-09-01 陈继贵 Sequential fecal occult blood collecting and detecting integrated device
CN109444122A (en) * 2018-10-26 2019-03-08 南通大学 A kind of Test paper
CN109444122B (en) * 2018-10-26 2024-04-12 南通大学 Test paper

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Application publication date: 20120125