CN102646351A - In vitro bionic cycle test system for simulating flowing of blood in arterial aneurysm of human body - Google Patents
In vitro bionic cycle test system for simulating flowing of blood in arterial aneurysm of human body Download PDFInfo
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- CN102646351A CN102646351A CN2012100461719A CN201210046171A CN102646351A CN 102646351 A CN102646351 A CN 102646351A CN 2012100461719 A CN2012100461719 A CN 2012100461719A CN 201210046171 A CN201210046171 A CN 201210046171A CN 102646351 A CN102646351 A CN 102646351A
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Abstract
The invention discloses an in vitro bionic cycle test system for simulating flowing of blood in arterial aneurysm of a human body under different heartbeat frequencies, relating to the field of biomedicine research on arterial aneurysm and being suitable for carrying out cycle simulating testing on the flowing condition of the blood in the arterial aneurysm of the human body under different heartbeat frequencies. The in vitro bionic cycle test system comprises an upper liquid storage box, a peristaltic pump, a laminar flow generator, an experimental section model, a flow meter, a lower liquid storage box, a cycle pump and a valve. The whole in vitro bionic cycle test system is communicated by a silicon rubber hose and a common rubber hose, fluid is controlled by the valve to flow or stop flowing; the silicon rubber hose is connected to the upper liquid storage box and is downwards connected with the laminar flow generator through the peristaltic pump, a pump head of the peristaltic pump is used for carrying out peristaltic extrusion on the silicon rubber hose; and the laminar flow generator is formed by banding a thin tube embedded in the common rubber hose. Fluid flows out of the laminar flow generator, enters the experimental section model through the common rubber hose, flows into the lower liquid storage box through the flow meter, and returns to the upper liquid storage box through the cycle pump, so that the whole cycle flowing process is completed.
Description
Technical field
The present invention relates to the biomedical research field, particularly a kind of being applicable under different palmic rates, to human body artery knurl inner blood mobility status carry out circulating analog external bionical circulation experiment system.
Background technology
The outer bionical circulation experiment of blood of human body liquid system utilizes the similarity principle that flows to simulate true blood flow situation, thereby obtains and the true close information of blood flow.Low, the strong operability of external bionical experimental system cost, the experiment conclusion and the real case degree of approach are high, so extensively used the modern biomedical research field.
At present, the simulation external bionical experiment circulation system that the human body inner blood flows under given heart rate is more at home and abroad, wherein typically studies like document [1] Zhang X; Yao Z; Zhang Y, et al.Experimental and computational studies on the flow fields in aortic aneurysms associated with deployment of AAA sten-grafts.Acta Mech Sin, 2007; 23:495-501 and document [2] Lieber BB; Livescu V, Hopkins LN, et al.Particle image velocimetry assessment of stent design influence on intra-aneurysmal flow [J] .Annals of Biomedical Engineer ing; 2002,30:768-777.But human heart rate's distribution range broad normal adult heart rate 60 times/assign to distribution all arranged between 100 times/minute, the heart rate outside this interval is generally ill heart rate.And the variation of palmic rate is producing significant effects to the haemodynamics factor, to aneurysmal formation, grow, break and knurl in the formation of thrombus confidential relation is arranged.Its Mechanisms between the palmic rate that for this reason conducts a research and the haemodynamics factor seems particularly necessary and meaningful to the formation mechanism of understanding and be familiar with thrombus in aneurysmal development and evolution process and the knurl.
The flow state of blood of human body under different palmic rates, to eddy current in VPV, wall shear stress and the knurl to influence rule all different, and palmic rate can't realize regulating with accurate fast in traditional external bionical experimental study at present.So the simulation to blood flow state under the different palmic rates has caused bigger limitation; Thereby be unfavorable for the mechanism of action between research changes in heart rate and the haemodynamics factor, bring very big difficulty for the formation mechanism of being familiar with and understanding thrombus in aneurysmal development and evolution process and the knurl.
In order to study palmic rate to the influence of haemodynamics factor mechanism, need one can fine simulation heart wriggling peristaltic pump, and the wriggling of heart is very high to two parameter requests of the blood flow state in the human body artery pipe.First parameter is the Reynolds number that characterizes fluid flow state.Second parameter is for characterizing the Wo Mosili number of true blood flow degree of pulsatility.The magnitude range of these two parameter values has determined whether external bionical experiment blood flow state is approximate with the blood flow state in the true aneurysm pipe, has also determined the validity and the rationality of whole external bionical experimental system.
Summary of the invention
The object of the invention has been to provide a kind of external bionical circulation experiment system of simulating that human body aneurysm inner blood flows; It can be simulated under the different palmic rates; Blood flow state in the aneurysm facilitates for obtaining in the inner VPV distribution of knurl body, knurl body wall face shear stress, the knurl data such as eddy current.
In order to achieve the above object; The present invention adopts following technical scheme to be achieved: comprise through pipeline linking to each other and forming the upper and lower liquid reserve tank of closed loop; In upper and lower liquid reserve tank, be provided with fluid working substance; The outlet of last liquid reserve tank is connected with the laminar flow generator through silica gel hose, and this silica gel hose passes peristaltic pump, and the inlet that the laminar flow generator is taken into account down liquid reserve tank through rubber tube and experimental section, flow links to each other; The outlet of following liquid reserve tank links to each other with the inlet of last liquid reserve tank through rubber tube, and on this pipeline, ebullator is installed also.
Described upper and lower liquid reserve tank adopts the thick organic glass processing and fabricating of 10mm to form.
The described pressure of going up liquid reserve tank 1 outlet is 13kPa, and on the outlet silica gel hose of last liquid reserve tank 1, valve is installed.
The rotating speed adjustable of described peristaltic pump, its rotating speed are 60rpm～120rpm, and silica gel hose passes between peristaltic pump pump head stationary shaft and the peristaltic pump squeegee roller.
Described laminar flow generator is that 1mm, external diameter are that 1.1mm, length are that the hollow tubule of 10cm is tied up and formed by internal diameter, and passes rubber tube.
Described experimental section is fixed in the organic glass chamber, and flowing full body working medium is filled in this organic glass chamber.
Described fluid working substance adopts glycerine water solution, and its temperature is 25 ± 1 ℃, and kinematic viscosity is 12.38 * 10
-6m
2/ s, massfraction are 64%, and density is 1.125g/cm
3
The present invention is communicated with through silica gel hose and rubber tube; Fluid working substance exports out through silica gel hose, peristaltic pump, laminar flow generator with as sebific duct from last liquid reserve tank and enters into experimental section; After flowmeter flow into down liquid reserve tank; Make fluid be back to liquid reserve tank through ebullator again, accomplish the whole circulation flow process.Simulate the heartbeat frequency through regulating the peristaltic pump rotating speed, control pump head squeegee roller produces approximate human body artery inner blood flow state to the extruding of silica gel hose.Adopt outer testing system (PIV of particle image velocimetry system commonly used) focus measurement and research aneurysm knurl flow field information; Analyze through the poster processing soft stream field data; Obtain information such as VPV distribution in the aneurysm knurl body, knurl body wall face shear stress, the interior eddy current state of knurl indirectly; For the mechanism of action between the formation of researching and analysing thrombus in palmic rate and aneurysmal development and evolution process and the knurl is provided convenience, understand thereby promoted biomedical research more deep and more comprehensive understanding aspect the aneurysm disease.
Description of drawings
Fig. 1 is external bionical circulation experiment system and device figure of the present invention;
Fig. 2 is a peristaltic pump header structure synoptic diagram in the external bionical circulation experiment system and device of the present invention;
Fig. 3 is an external bionical circulation experiment system and device of the present invention middle level flow-generator structural representation;
Wherein: 1, go up liquid reserve tank; 2, glycerine water solution; 3, valve; 4, silica gel hose; 5, peristaltic pump; 6, laminar flow generator; 7, experimental section; 8, flowmeter; 9, following liquid reserve tank; 10, rubber hose; 11, ebullator; 12, pump head stationary shaft; 13, peristaltic pump squeegee roller; 14, tubule.
Embodiment
Below in conjunction with accompanying drawing the present invention is done further explain.
Referring to Fig. 1, the present invention includes through pipeline and link to each other and form the upper and lower liquid reserve tank 1,9 of closed loop, upper and lower liquid reserve tank 1,9 adopts the thick organic glass processing and fabricating of 10mm to form; In upper and lower liquid reserve tank 1,9, be provided with fluid working substance 2, the outlet of last liquid reserve tank 1 is connected with laminar flow generator 6 through the silica gel hose 4 that has valve 3, and this silica gel hose 4 passes peristaltic pump 5; Laminar flow generator 6 links to each other through the inlet of rubber tube 10 and experimental section 7, flowmeter 8 and following liquid reserve tank 9, because empirical model is a glass curve, for avoiding in measuring process; Laser is fixed in experimental section 7 in the organic glass chamber the scattering process of curved surface, and flowing full body working medium is filled in this organic glass chamber; The outlet of following liquid reserve tank 9 links to each other through the inlet of rubber tube 10 with last liquid reserve tank 1, and on this pipeline, ebullator 11 is installed also, in the experimental system course of work; Fluid volume in the liquid reserve tank is constant; It is consistent with the human vein internal pressure to guarantee to enter into the preceding hydrostatic pressure of peristaltic pump, and about 13kPa, fluid working substance adopts glycerine water solution; Its temperature is 25 ± 1 ℃, and kinematic viscosity is 12.38 * 10
-6m
2/ s, massfraction are 64%, and density is 1.125g/cm
3, its refractive index is the same basically with the glass empirical model to be about 1.5, can reduce the scattering of pipe wall to laser like this.
Referring to Fig. 2, the rotating speed adjustable of peristaltic pump 5 of the present invention, its rotating speed is 60rpm～120rpm, and silica gel hose 4 passes between peristaltic pump 5 pump head stationary shaft 12 and the peristaltic pump squeegee roller 13.13 pairs of peristaltic pump squeegee rollers push through its inner silica gel hose 4, produce pulsating fluid with this.Regulate rotating speed, the extruding frequency of 13 pairs of silica gel hoses 4 of peristaltic pump squeegee roller is different, produces the pulsating fluid of different flow states.Its Reynolds number that characterizes fluid flow state of the pulsating fluid that produces is 100～1000, and the Wo Mosili number that characterizes the fluid pulsation degree matches with true blood flow scope 3～6.In order to study under the different palmic rates, the change and progress rule of the haemodynamics factor in the aneurysm realizes that through regulating the peristaltic pump rotating speed size of tachometer value is promptly represented the size of heart rate number.Through above-mentioned, can make things convenient for the blood flow situation under the different palmic rates of research greatly.And the operating mode of this external bionical experimental system is higher in the quality of data that 60rpm～120rpm obtains, promptly this external bionical experimental system can the modeling effort heart rate 60 times/assign to the blood flow information of 120 times/minute situations.
Referring to Fig. 3, laminar flow generator 6 of the present invention is that 1mm, external diameter are that 1.1mm, length are that the hollow tubule 14 of 10cm is tied up and formed by internal diameter, and passes rubber tube 10.There is pulsation to a certain degree in the fluid that flows out through the peristaltic pump extruding, and the flow state turbulence level of pulsating fluid is bigger, adds at the peristaltic pump outflow end and puts laminar flow generator 6.
The present invention is fixed on peristaltic pump on the experiment table top, and should experiment table top surface level friction.Last liquid reserve tank places the fixed support top, and fixed support is fixed on the experiment table top.The experimental section model makes things convenient for installation and removal, and is placed in the chamber, a fixing transparent uncovered organic glass side, the built-in flowing full in chamber, the uncovered organic glass side matter of starting building, and said organic glass side is fixed in the chamber on the experiment table top.Flow working medium is provided with peripheral filtrator, eliminates the influence of impurity to flowing in the total system device.Fixed support all adopts stainless-steel pipe, and said experiment table top is chosen optical table.In experimentation, control peristaltic pump and ebullator start synchronously, stop synchronously.Experiment is in time unclamped the peristaltic pump pump head after finishing, and discharges the fluid working substance in the silica gel hose, to increase the service life.
In the experiment cyclic process, flow is monitored in real time; The monitoring average discharge; Guarantee that the fluctuations in discharge cycle is consistent with true heart beat cycle; Flowmeter is chosen for the vane type micro-flowmeter, can reduce the resistance that produces when downstream fluid is flowed through flowmeter like this to upper reaches influence on flow field, can obtain the higher experimental data of quality.
Enter into liquid reserve tank down at fluid working substance, this moment, the ON cycle pump was realized dynamically circulation continuously, simulated the sanguimotor flow state of human body with this.The flow of ebullator and the flow of peristaltic pump are consistent, guarantee that the fluid level that goes up in the liquid reserve tank is invariable, i.e. simulation enters into the venous blood flow constant pressure before the heart wriggling, about 13kPa.
The present invention simulates the heartbeat frequency through regulating the peristaltic pump rotating speed, and the extruding of 13 pairs of silica gel hoses of control pump head squeegee roller produces approximate human body artery inner blood flow state.Adopt outer testing system (PIV of particle image velocimetry system commonly used) focus measurement and research aneurysm knurl flow field information; Analyze through the poster processing soft stream field data; Obtain information such as VPV distribution in the aneurysm knurl body, knurl body wall face shear stress, the interior eddy current state of knurl indirectly; For the mechanism of action between the formation of researching and analysing thrombus in palmic rate and aneurysmal development and evolution process and the knurl is provided convenience, understand thereby promoted biomedical research more deep and more comprehensive understanding aspect the aneurysm disease.
Claims (7)
1. external bionical circulation experiment system of simulating that human body aneurysm inner blood flows; It is characterized in that: comprise through pipeline linking to each other and forming the upper and lower liquid reserve tank (1,9) of closed loop; In upper and lower liquid reserve tank (1,9), be provided with fluid working substance (2); The outlet of last liquid reserve tank (1) is connected with laminar flow generator (6) through silica gel hose (4), and this silica gel hose (4) passes peristaltic pump (5), laminar flow generator (6) through rubber tube (10) and experimental section (7), flowmeter (8) and down the inlet of liquid reserve tank (9) link to each other; The outlet of following liquid reserve tank (9) links to each other through the inlet of rubber tube (10) with last liquid reserve tank (1), and ebullator (11) also is installed on this pipeline.
2. the external bionical circulation experiment system that simulation human body aneurysm inner blood according to claim 1 flows, it is characterized in that: described upper and lower liquid reserve tank (1,9) adopts the thick organic glass processing and fabricating of 10mm to form.
3. the external bionical circulation experiment system that simulation human body aneurysm inner blood according to claim 1 flows; It is characterized in that: the described pressure of going up liquid reserve tank (1) outlet is 13kPa, and on the outlet silica gel hose (4) of last liquid reserve tank (1), valve (3) is installed.
4. the external bionical circulation experiment system that simulation human body aneurysm inner blood according to claim 1 flows; It is characterized in that: the rotating speed adjustable of described peristaltic pump (5); Its rotating speed is 60rpm～120rpm, and silica gel hose (4) passes between peristaltic pump (5) pump head stationary shaft (12) and the peristaltic pump squeegee roller (13).
5. the external bionical circulation experiment system that simulation human body aneurysm inner blood according to claim 1 flows; It is characterized in that: described laminar flow generator (6) is that 1mm, external diameter are that 1.1mm, length are that the hollow tubule (14) of 10cm is tied up and formed by internal diameter, and passes rubber tube (10).
6. the external bionical circulation experiment system that simulation human body aneurysm inner blood according to claim 1 flows, it is characterized in that: described experimental section (7) is fixed in the organic glass chamber, and flowing full body working medium is filled in this organic glass chamber.
7. the external bionical circulation experiment system that simulation human body aneurysm inner blood according to claim 1 flows, it is characterized in that: described fluid working substance adopts glycerine water solution, and its temperature is 25 ± 1 ℃, and kinematic viscosity is 12.38 * 10
-6m
2/ s, massfraction are 64%, and density is 1.125g/cm
3
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| CN104658363A (en) * | 2015-02-13 | 2015-05-27 | 浙江省人民医院 | Training mold for Da Vinci robot system |
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| CN105784406A (en) * | 2016-05-12 | 2016-07-20 | 北京精密机电控制设备研究所 | Extracorporal integrated test system for ventricular assist devices |
| CN106205326A (en) * | 2016-09-06 | 2016-12-07 | 南方医科大学南方医院 | Liquid Circulated power system based on breath cycle parameter |
| CN106205327A (en) * | 2016-09-06 | 2016-12-07 | 南方医科大学南方医院 | The cranium brain model of liquid Circulated power system can be connected |
| DE102015008050A1 (en) | 2015-06-19 | 2016-12-22 | Technische Universität Ilmenau | Arrangement in the form of a model system for the reproduction of maternal and fetal pulse curves for non-invasive transabdominal plethysmography |
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| CN109342278A (en) * | 2018-11-28 | 2019-02-15 | 北京航空航天大学 | A kind of particle image velocimetry device with adjustable fixed structure |
| CN109364356A (en) * | 2018-11-14 | 2019-02-22 | 浙江理工大学 | A kind of the magnetic target therapy device and its control method of multichannel analog biology body circulation |
| RU187572U1 (en) * | 2018-12-13 | 2019-03-12 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Тамбовский государственный технический университет" (ФГБОУ ВО "ТГТУ") | Device for generating pulsating flows in phantoms of blood vessels |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030097040A1 (en) * | 2001-06-08 | 2003-05-22 | The Trustees Of The University Of Pennsylvania | Ex vivo remodeling of excised blood vessels for vascular grafts |
| CN101347360A (en) * | 2008-08-12 | 2009-01-21 | 西安交通大学 | Apparatus based on blood vessel stent structure for testing blood mobility |
| CN102068245A (en) * | 2011-01-05 | 2011-05-25 | 东南大学 | Method and device for testing flowing property of blood flow at lesion site where blood vessel stent is implanted |
-
2012
- 2012-02-27 CN CN2012100461719A patent/CN102646351A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030097040A1 (en) * | 2001-06-08 | 2003-05-22 | The Trustees Of The University Of Pennsylvania | Ex vivo remodeling of excised blood vessels for vascular grafts |
| CN101347360A (en) * | 2008-08-12 | 2009-01-21 | 西安交通大学 | Apparatus based on blood vessel stent structure for testing blood mobility |
| CN102068245A (en) * | 2011-01-05 | 2011-05-25 | 东南大学 | Method and device for testing flowing property of blood flow at lesion site where blood vessel stent is implanted |
Non-Patent Citations (1)
| Title |
|---|
| T.M.LIOU ET AL: "《In vitro visualization of pulsatile flows in a lateral aneurysm anchored on a curved parent vessel with stent placement》", 《PROCEEDINGS OF PSFVIP-4》, 5 June 2003 (2003-06-05) * |
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