CN1128353A - 用于监测患者血液中待分析物质的分析系统 - Google Patents

用于监测患者血液中待分析物质的分析系统 Download PDF

Info

Publication number
CN1128353A
CN1128353A CN95105402A CN95105402A CN1128353A CN 1128353 A CN1128353 A CN 1128353A CN 95105402 A CN95105402 A CN 95105402A CN 95105402 A CN95105402 A CN 95105402A CN 1128353 A CN1128353 A CN 1128353A
Authority
CN
China
Prior art keywords
data
sensor unit
analysis data
sensor
analytic system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN95105402A
Other languages
English (en)
Inventor
D·布克
H·-P·哈尔
P·布拉斯堡
R·科图拉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of CN1128353A publication Critical patent/CN1128353A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6822—Neck
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/903—Radio telemetry

Abstract

用于监测患者血液中待分析物质浓度的分析系统，包括含有试剂的分析元件(12)和评价仪器，评价仪器含有测量装置，该测量装置用于测量因被分析物质和试剂相互反应时发生的变化，由此根据如此获得的测量值来确定代表元件分析数据CA的分析数据。

Description

用于监测患者血液中待分析物质的分析系统
本发明涉及一种用于监测存在于患者血液中的待分析物质(分析物)的分析系统。
在许多情况下，必须定期地对血液中被分析物的浓度进行监测。在需要根据特殊物质的浓度进行常规药物治疗时尤其是这样。最典型的例子是糖尿病。这种病的患者应该经常地监测他们的血糖指标以便在需要时配合胰岛素注射并由此将血糖指标(即，血液中的葡萄糖浓度)保持在特定的范围内。要避免血糖高于该范围(高血糖)或降至该范围以下(低血糖)，同时尽可能可靠地避免两种临界的严重情况和严重的长期疾病(例如丧失视力)。
尽管本发明还适用于其它需要分析的物质，但是其主要涉及血糖浓度的监测。应该认识到，下文中有关葡萄糖测定的任何讨论均不对本发明的普通应用构成限制。
用于监测血糖浓度的传统分析系统包括固态分析元件也称为测试载体和评价仪器。通常，分析元件和评价仪器相互间特别匹配并由相同的制造商作为一个系统提供。
分析元件包含试剂。当使元件与测试样品相接触时，样品中的被分析物和试剂之间发生反应并在分析元件上产生可进行实际测量的变化，该变化与所说物质的浓度有关。评价仪器包括测量所说变化的测量系统和根据在测量所说变化时得到的测量值对被分析物的浓度进行测定的电子设备。先进的装置采用微机作为评价用的电子设备，它能够进行软件控制的数字处理，由此将测量值转换成与被分析物质的浓度相应的信号。通常，这些分析数据以浓度的单位显示在字母数字显示器上。然而，本发明意义上的用语“分析数据”还包括用其它方式表示分析结果的电信号，例如，对与被分析物质浓度有关的信息显示偏差进行控制的信号，如“理想范围”、“上标准范围”、“上危险区”，等等。
众所周知，从反应原理和与浓度有关的可测量的变化方面来看，不同种类的分析元件涉及不同的物理化学原理。传统的分析系统主要是光度学式的或电化学式的。
就光度学式的分析系统而言，分析元件包括试剂系统。试剂与被分析物的反应产生光度学上可探测的变化(颜色变化)。通常，将试剂置于多孔塑料或纸模上以形成分析元件的测试区，所说纸模的颜色随浓度而变化。该颜色变化可用反射光度计定量测定。
电化学式分析元件包括电化学试剂系统。该试剂与被分析物的反应影响分析元件两端的电势和/或当所说两端的电压不变时影响分析元件两端的电流。因此，在这种情况下，实际上可测得的变量是电压或电流而且该变量是通过与设备相组合的相应电压或电流传感器进行测定的。最好再一次使用微机评价电子器件将所说的与被分析物质浓度有关的测量值的变化转换成分析数据(被分析物质的浓度)。
用包含试剂的分析元件进行操作的分析系统(以下称为“元件分析系统”)具有较高的精度并且极容易操作以致于患者自己可以使用它们对血糖浓度进行经常性的监测(家庭监测)。然而，它们具有明显的缺点，即每次进行特定的分析时，需要抽取血滴然后使血滴与分析元件相接触。通常，这个过程是通过刺破手指来完成的，换句话说，每次分析都会带来有感染危险的痛苦的皮肤伤害。这种方法称为“侵入式分析”。
为了在提高精度和以少量的侵入获取样品的同时连续监测血液中待分析物质的浓度，本发明在前面讨论的那种分析系统的基础上公开了一种系统，该系统包括可以在患者身上移动的传感器单元，传感器单元由无试剂的传感器构成，其可直接地在患者身上测量与被分析物质浓度有关的参数，所说单元进一步包括用于无线传输数据信号的发送器。所说的系统还包括传感器评价电子设备，其用于根据被测的参数的传感器测量值对传感器分析数据进行测定。评价仪器是整个分析元件/传感器监测系统的中央单元，其包括用于接收来自传感器单元的数据信号的无线接收器，此外，还包括根据来自分析元件的分析数据(“元件分析数据”)对传感器分析数据进行校正的校正装置和用于长期储存分析数据的数据存储器。
用于测定血液分析物的无试剂传感器分析系统已在很多实施例中进行了描述。这些系统已足以适用对某些待分析物质进行分析(特别是血氧值和血气浓度)。然而，对一些其它待分析物质而言，特别是葡萄糖，这些系统还不是十分适用。
在J.clin.chem.clin.Biochem.26，1988，第201-8页上由J.D.Kruse-Jareese所著的”PHYSICOCHEMICALDETERMINATION OF GLUCOSE IN VIVO”文中给出了测定葡萄糖的非侵入式测量方法。
为了实现对组织中被分析物质浓度进行分析测定的目的，本发明主要采用了照射光和活体组织(最好是表皮组织)之闻相互作用的系统。假设(血液循环)组织中分析物的浓度实际上与血液中的相应浓度有极大的关系。在这种系统中，传感器单元包括用于照射组织的光发射器。此外还设有光探测器，在光与组织相互作用时，通过光探测器可以检测离开身体部分的光从而确定可测量的物理光特性，该特性随光与组织的相互作用而变化。在该方法中可测量的物理特性构成了与被分析物质浓度有关的参数。
目前已知的大多数这类方法以光谱分析为基础。其中通过确定对光波长的光吸收关系来测定吸收特性(因被分析物质分子的振动和转动状态产生的)。实际上从窄带光发射器发出的是不同波长的普通光并且自光探测器对接收到的光进行测量。此外，照射光也可以来自宽带光发射器并可以在探测侧进行选择性的波长测量。上述所讨论的分子吸收带(特别是葡萄糖)处于远红外光区。然而在该光区内组织水能引起强烈的光吸收，所以，大多数人建议在近红外光区测量波长，由此可以探测分子振动和转动状态的谐波。例如，EP-A0160768，WO93/00856和美国专利5028787已对这种系统进行了描述。
在本发明特别优选的实施例中，使用了一种根据组织的折射率来测定光参数的传感器系统。该方法实际上基于这样一个发现，即可以将组织中与葡萄糖浓度有关的液体折射率的变化作为和葡萄糖浓度相关的参数。
为了实现这一方法，有入建议采用一种测量技术对受通过组织散射中心的多次散射光影响的信号进行测定，该方法已在国际专利申请PCT/DE93/01058中进行了描述。在所述出版物描述的测量条件下，多次散射增强了因折射率变化而产生的效果，所说的这种增强可以通过较强的和因此更容易测得的信号变化得以确定。引用的参考文献包含了更详细的内容，可将它们作为参考内容与本发明公开的内容相结合。
德国专利申请4337570描述了一种以确定与光在组织中的传播时间相应的光参数为基础的葡萄糖分析方法。这种传播时间参数可以正好是超短光脉冲的间隔时间。然而，用测定与组织中的葡萄糖浓度有关的时间传播参数来代替测定光在组织中的相移要简单得多。
最近，同时申请的德国专利申请4415728“METHODAND DEVICEFOR ANALYZING GLUCOSE IN A BIOLOGICSAL SAMPLE”中描述了如何用低相干性干涉测量法确定组织折射率。可以直接通过确定光在组织中的光路进行这种测定或直接用确定组织中光散系数的方式进行这种测定。液体的折射率和组织散射中心(例如细胞)的折射率之间的关系对散射系数起决定性的作用。所说申请的内容在本说明书中引用作为参考文献。
在本发明中将这样一个非侵入式传感器分析系统与一个用以试剂为基础的分析系统操作的侵入式分析系统相结合。传感器分析系统包括一个带在患者身体上的可移动的电池驱动传感器单元和一个评价装置，该评价装置在某种意义上是固定的，它不带在患者身上但处于一个合适的位置上，例如在患者的居室内。然而，中央单元最好是小的和重量轻的，其足以便于患者在离开所说居室一段时间(例如几天)对随身携带。基本单元和中央单元通过无线数据传输方式相连通。所说的连通可以通过多种方式实现，例如使用IR光，高频无线电波或超声波。
装在患者身上的传感器单元和固定的中央单元共同完成传感器分析系统的任务。可以将该系统的任务分配给不同方式的两个单元。通常，可以将传感器单元设计成无自身智能，它的任务仅仅是测定传感器测量值并将其以无线的方式传送至中央单元。然而，最好是将传感器单元设计成带有自身智能，也就是说，它包括一个作为评价装置的微机数据处理系统，其用于根据传感器单元中至少一个传感器的测量值来确定传感器分析数据，所说的测量值对应于被分析物质的浓度。因此，可以在传感器单元上设置它自己的显示器以指示被分析物质的浓度数据，例如当葡萄糖浓度向上或向下超过特定的范围时仅仅发出声响或发光警报。此外，在该实施例中传感器单元和中央单元之间的连通最好是相互的，也就是说，不仅将来自分析元件的分析数据从传感器单元传输到中央单元，而且反过来也一样，可以使数据从中央单元发送到传感器单元。该特征特别适合于对用于确定被分析物质浓度的传感器单元进行校正。
此外，传感器分析系统的中央单元同时作为侵入式元件分析系统的评价仪器并根据元件分析分系统的测试数据对传感器分析分系统进行校正，这一点在本发明中是很重要的。
与过去通常使用的分析元件相比，本发明所说分析系统的一个显著特点是可以连续实时地提供电流分析数据和在任何时间都能获得有关葡萄糖浓度变化率的可靠信息。这对于那些有糖尿病危险，例如在晚间休息时出现高血糖或低血糖趋向的糖尿病患者来说是非常重要的。此外，当增加身体运动量，例如在进行体育运动时对葡萄糖进行参数监测是极其重要的。对于用胰岛素治疗的糖尿病患者来说，提供这样的可能性，即定量地测定葡萄糖值的瞬时趋势(升高或降低)从而确定所需胰岛素的量也是非常重要的。
下面将通过附图中所示的示例性实施例对本发明进行说明。
图1是本发明所述分析系统中各部件的透视图；
图2是方框图；
图3是作为时间函数的分析数据的曲线图，其表示校正过程；
图4是带有第一实施例中图形显示器的中央单元的顶视图；
图5是带有第二实施例中图形显示器的中央单元的顶视图。
图1中所示的完整的分析元件/传感器系统IASS1包括置于患者身体上的传感器单元2和通过用箭头4表示的无线数据传输与传感器单元2连通的中央单元3。在所示的最佳实施例中传感器单元2包括基本单元6和两个通过电缆9与基本单元6相连的传感器7、8。基本单元6可以通过颈圈戴在患者的脖子上。显然也可以用其它的方式固定基本单元，例如用肩圈或带将其固定在患者身上。
原则上可以只用一个传感器进行操作。然而，最好是使用二个或多个传感器以便同时在身体的几个测试部位上测量与葡萄糖浓度有关的参数，由此，通过例如平均测量值或根据预定的安全标准选择较好的测试值可提高精度。
中央单元3具有通常用于元件分析系统中的评价仪器的典型特征。在所示的情况下，其用于评价由带有基层14和测试区15的葡萄糖测试条13构成的分析元件12。为了进行评价，将分析元件12插入位于装置3的挡板18下部的测试通道17中。中央单元3上设有用于操作该单元的按键20。显示器21用于信息输出，特别用于显示分析数据。
用于对与中央单元3中合为一体的分析元件进行评价的评价装置是一种传统设计的装置，因此不需要进行更详细的描述。在许多出版物中都可获得相关的信息。例如，欧洲专利申请0492326中描述了一种普通的仪器设计，而在欧洲专利申请0075767中描述了一种实用的测量电子设备。
图2是中央单元3和传感器单元2的基本功能元件的方框图。
中央单元3包括一个用于测量与被分析物质浓度变化有关的分析元件12的变化的测量装置23，例如一个测量测试区15颜色变化的反射光度计。测量装置23产生与随浓度变化的测量值R相应的电信号。
将测量值R送至作为微机25一部分的评价用电子设备24，微机25还包含一个存储单元26。评价用电子设备24借助于存储在存储器26中的用于描述所需浓度C和测试值R的函数关系的评价曲线，即CA＝f(R)，算出所要寻找的被分析物质的浓度C并将这些元件分析数据CA输入到存储器26进而存储在该存储器中。分析数据CA自动地或通过特殊指令显示在显示器21中。
可以将评价曲线CA＝f(R)永久地储存在中央单元3中。然而，最好是对每一批新生产的分析元件12使用独立的、一组专用的评价曲线并通过合适的数据媒体将其以机器可读出的形式传输到中央单元。为此，中央单元包括一个数据读出器28，例如，条形码读出器以读出固定在分析元件本身或其它码载体上的条形码。该条形码包含在每一组分析元件上并且包含一组专用的评价曲线。更详细的内容公开在欧洲专利申请0492326中。
除了上述在分析元件评价仪器中的传统功能部件之外，中央单元3还包括用于对数据进行无线传输的无线电收发器29，和传感器校正装置30，该校正装置在实际中最好由软件构成，因此在图3中示为微机25的一部分。这些部件以下面将要进一步描述的方式将分析元件分系统与传感器分系统相连通。
传感器单元2的基本单元5包含与至少一个传感器7相连的传感器电子设备32。这个传感器电子设备32包括用于操作传感器7并进而在患者身体上测量与葡萄糖浓度有关的参数的元件。最佳实施例包括光照射装置，该装置可以是装在传感器7本体上并通过电缆9供电的发光二极管。此外，在基本元件5中可以采用一个或多个光源，包含光纤的电缆9将光输送到传感器7中。相应地，在传感器7和/或基本单元6中设置半导体光探测器以便探测与患者的组织相互作用之后的光。传感器电子设备还进一步包括诸如放大器之类的电子器件以便将接收到的信号处理成与被分析物质的浓度有关的传感器测量值S。将传感器测量值S送至传感器评价装置33，该装置最好是以微机系统34的部件的形式构成，微机系统34还包括存储单元其与基本单元6合为一体。实际上其与分析元件评价仪器24相似。传感器评价装置33利用存储在存储单元35中的评价曲线CS＝g(S)并通过测量值S算出分析数据(浓度)C，所说的计算实际上是由软件控制的。将评价曲线CS＝g(S)以无线的方式从中央单元3输送到基本单元6。为此基本单元6上装有无线电收发器36，该收发器可与中央单元上的无线电收发器29共同作用实现两个单元3、6之间的无线数据传输。
将算出的浓度数据CS储存在存储单元35中。这些数据可以不受中央单元3的控制通过输出单元38输出，基本单元6中的输出单元38的设计应选择最小尺寸和最小的电池能耗。它的主要目的是在葡萄糖浓度的临界极限值超过危险范围的情况下发出警告。合适的是输出单元38可以由带有三个发光二极管(正常范围，高糖危险，低糖危险)的发光二极管显示器构成。此外，还可以提供声信号。
图2中还示出了作为基本单元6一部分的电源电池40。该电池很重要，因为分析传感器的能耗比较高。因此，电池40应该是可再充电的而且应在基本单元6中组合一个电压监视器(未示出)以便及时地发出需要更换电池的警报。
在使用本发明的分析系统对，带有传感器单元2的患者可以离开静置的中央单元3一段时间而不会出现问题。在这段时间内，传感器分析数据CS存储在存储器35中。回家后，当患者离中央单元3足够近使得单元3和6之间可进行无线数据交换时，可使同时得到的传感器分析数据CS从存储器35传送到中央单元的存储器26中。患者可用分析元件12在任何时间进行校正。合适的是，中央单元3包括提醒患者借助校正用分析元件经常进行分析的时间保持装置。每次进行这样的分析时，在中央单元3中确定一条新的评价曲线CS＝g(S)并将该曲线传输到传感器单元2。下面将讨论在整个系统校正期间单元3和6的结合情况。
如上所述，元件分析数据CA是通过评价曲线CA＝f(R)进行校正的，评价曲线最好是以机器可读码的形式通过数据读出器28输入到存储器26中。因此，由分析元件产生的分析数据CA将是足够准确的。当患者刺破他/她的手指得到血滴41，然后，借助分析元件12和测量及评价用电子设备23、24进行分析时就可获得CA值。这种测量可以以一定的时间间隔进行，例如，一天进行一次或二次。图3表示以数据点39的形式在时间t1到t5测得的分析数据。
通过用于测量和评价的电子器件32、33，传感器7产生传感器分析数据CS，所说的数据产生应连续进行或以如此小的间隔进行，即实际上将连续的CS值序列存储在存储器35中并且当单元2和3处于数据相互传输模式时能够将序列值输送到中央单元3。图3用虚线A表示CS值的时间函数。元件分析数据CA用于校正传感器分析数据CS。该过程例如可用这样的方式进行，即在每一次校正时间t1到t5由校正单元30对分析数据CA和存储在存储器26中的CS进行比较。传感器校正装置30通过比较后确定一条新的、正确的评价曲线CS＝g(S)，然后，通过无线电收发器29、36将该曲线传输到基本单元6上，在此，存储器35将采用新的评价曲线借助传感器评价用的电子设备33对以后的传感器分析数据进行计算。在校正期间确定的新的评价曲线CS＝g(S)可同时用于对至少早在前面进行元件分析时就已存储在存储器26中的传感器分析数据进行反校正。因此，就图3所示的实例而言，根据在时间t2获得的浓度值CA(t2)可以对时间t1的值进行校正。类似的思路可用于从时间t3反推到时间t2等。校正后传感器分析数据的正确函数在图3中用实线B表示。
该校正方法仅作为例子描述。很显然，它还可以用不同的方式来完成，特别是那些适应于用来测定分析数据CS或CA的特定评价方法的方式。用于根据大量测试值(例如在很多波长下的强度值)测定一个浓度值CS的数字数学方法是特别适用的，这些方法之一是部分最小二乘法。
传感器单元2和中央单元2和3中的存储器35和26的存储容量分别与特定的用途相配匹。存储器35仅用于相对少量数据的中间存储，也就是说，仅存储在患者与他/她的传感器单元2一起离开中央单元3的最大时间间隔期间的浓度值。存储器35的容量优选能足以存储在至少两个小时，最好八个小时时间间隔内产生的数据量。通常，中央单元3的存储器26实际上更大并且能够存储在超长时间间隔(至少一星期)产生的分析和校正数据。合适的是在中央单元3上装有接口(未示出)由此根据后续处理的需要将所说数据传输到储存患者数据的医院中使用的PC机上。
如图1所示，中央单元3上的分析数据显示器可以是字母数字式的。中央单元3的显示器21最好是图形式的并且可以用图形表示传感器分析数据的时间序列。例如，在图4中所示的显示器中，瞬时葡萄糖值用中间黑带50表示。灰光显示区51对应于葡萄糖值的标准区域，而黑灰色区52表示上警告区(有高血糖的危险)并且下黑色区是下警告区(有低血糖的危险)。在显示器中箭头54表示葡萄糖值有升高的趋势。
在图5的曲线显示器中示出了在超过更大时间间隔内葡萄糖值的时间函数。在显示器的中部两个警告限56、57表示葡萄糖值的标准范围。葡萄糖值序列示为较宽的线58。有时该线58已经处在图5中的上警告区内，这时就需要例如注射胰岛素，即开始降糖。
图4和图5的图形显示器使本发明的系统具有能可靠地和实际上连续地确定葡萄糖值的特殊能力。为此，中央单元3的评价装置24(在此也表示基本单元6的评价装置33)最好还包括软件驱动的鉴别器以允许在任何时间对葡萄糖值序列和对该葡萄糖值的趋势进行测定。这种附加信息对糖尿病的治疗具有很高的价值。

Claims (12)

1.一种用于监测患者血液中待分析物质浓度的分析系统，包括：
含有试剂的分析元件(12)，该试剂在所说元件与患者血滴接触之后和待分析物质发生反应并在分析元件(12)中发生可测量的变化，所说变化与所说待分析物质的浓度有关；和评价仪器，其包括用于测量所说变化的测量装置(23)和评价装置(24)，该评价装置根据测量装置获得的测量值来确定表示元件分析数据CA的分析数据；
其特征在于：所说分析系统进一步包括(ⅰ)可在患者身体上移动的传感器单元(2)，所说的传感器单元(2)包含装在患者身体上以便对与待分析物质浓度有关的参数进行直接和无试剂测量的传感器(7)以及用于对数据信号进行无线传输的发送器(36)，和(ⅱ)传感器分析装置(34)，该装置用于根据由所说传感器测得的所说参数的测量值确定传感器分析数据CS；和所说评价仪器进一步包括(ⅰ)接收器(29)，其用于以无线形式接收来自传感器单元(2)的数据信号，(ⅱ)校正装置(30)，其根据元件分析数据CA对传感器分析数据CS进行校正和(ⅲ)
数据存储器(26)，其用于长期储存分析数据，由此，所说的评价仪器构成了整个分析元件/传感器监测系统(1)的中央单元(3)。
2.根据权利要求1所述的分析系统，其特征在于，所说的传感器单元(2)包括将光照射到患者身体局部组织上的光源和光探测器，该探测器在光与所说身体局部组织相互作用后对光进行探测以便确定随光与组织的相互作用而变化的物理光特性，从而构成与患者血液中待分析物质浓度有关的参数，根据所说的参数来确定传感器分析数据CS。
3.根据权利要求1和2中任何一项所说的分析系统，其特征在于，所说的传感器单元包括基本单元(6)和通过电缆(9)与基本单元(6)相连的传感器(7)，所说的基本单元还有用于传感器单元的电源(40)。
4.根据权利要求3所述的分析系统，其特征在于，所说的传感器单元(2)包括至少两个通过电缆(9)与同一个基本单元(6)相连的传感器(7，8)。
5.根据上述任何一项权利要求所述的分析系统，其特征在于，所说传感器单元(2)包括用于确定所说传感器分析数据CS的传感器分析装置(33)。
6.根据权利要求5所述的分析系统，其特征在于所说的传感器单元(2)包括显示装置38，其用于显示表示所说传感器分析数据CS的信息。
7.根据权利要求5或6中任何一项所说的分析系统，其特征在于，所说传感器单元(2)的发送器(36)和所说中央单元(3)的接收器(29)适于构成在传感器单元(2)和中央单元(3)之间进行相互闻数据交换的收发器系统。
8.根据上述任何一项权利要求所述的分析系统，其特征在于，传感器单元(2)包括存储器(35)，其适用于存储在至少两个小时最好是在八个小时的时间间隔内确定的传感器分析数据CS。
9.根据上述任何一项权利要求所述的分析系统，其特征在于，中央单元包括图形显示器(21)，其用图形表示传感器分析数据CS的时间函数关系。
10.根据权利要求9所述的分析系统，其特征在于，在图形显示器上可以显示传感器分析数据的时间函数关系或它们的变化趋势的多个不同显示模式(50-54；56-58)。
11.用于操作上述任何一项权利要求所述系统的方法，其特征在于，在用分析元件确定浓度值时，将所说的元件分析数据CA作为校正传感器分析数据CS的标准值。
12.根据权利要求11所述的方法，其特征在于，基于所说的标准值对传感器分析数据进行自动的反校正直到分析元件的前一次元件分析时为止。
CN95105402A 1994-05-05 1995-05-04 用于监测患者血液中待分析物质的分析系统 Pending CN1128353A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4415896A DE4415896A1 (de) 1994-05-05 1994-05-05 Analysesystem zur Überwachung der Konzentration eines Analyten im Blut eines Patienten
DEP4415896.3 1994-05-05

Publications (1)

Publication Number Publication Date
CN1128353A true CN1128353A (zh) 1996-08-07

Family

ID=6517389

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95105402A Pending CN1128353A (zh) 1994-05-05 1995-05-04 用于监测患者血液中待分析物质的分析系统

Country Status (18)

Country Link
US (1) US5507288B1 (zh)
EP (1) EP0680727B1 (zh)
JP (1) JP3568624B2 (zh)
KR (1) KR0163476B1 (zh)
CN (1) CN1128353A (zh)
AT (1) ATE242997T1 (zh)
AU (1) AU674474B2 (zh)
CA (1) CA2148569C (zh)
DE (2) DE4415896A1 (zh)
DK (1) DK0680727T3 (zh)
ES (1) ES2201083T3 (zh)
FI (1) FI952131A (zh)
HU (1) HUT75243A (zh)
IL (1) IL113569A (zh)
NO (1) NO951754L (zh)
NZ (1) NZ272000A (zh)
TW (1) TW366278B (zh)
ZA (1) ZA953585B (zh)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101233411A (zh) * 2005-07-29 2008-07-30 皇家飞利浦电子股份有限公司 在心脏疾病的诊断、管理和治疗期间对心脏利钠肽的监视
CN100407988C (zh) * 2001-01-02 2008-08-06 艾伯特糖尿病护理公司 分析物监测装置和该装置的使用方法
CN101368922B (zh) * 2003-04-10 2010-12-15 宇系科技有限公司 判断血糖浓度的方法
CN102307518A (zh) * 2009-02-03 2012-01-04 雅培糖尿病护理公司 分析物传感器和用于传感器插入的设备
CN102323309A (zh) * 2004-05-30 2012-01-18 埃葛梅崔克斯股份有限公司 测量设备和与之使用的方法
CN103251414A (zh) * 2007-06-21 2013-08-21 雅培糖尿病护理公司 用于分析物水平的检测的设备

Families Citing this family (678)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2050057A1 (en) 1991-03-04 1992-09-05 Adam Heller Interferant eliminating biosensors
US5593852A (en) * 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
WO2001037174A1 (en) 1992-11-17 2001-05-25 Health Hero Network, Inc. Method and system for improving adherence with a diet program or other medical regimen
US5956501A (en) * 1997-01-10 1999-09-21 Health Hero Network, Inc. Disease simulation system and method
US20010011224A1 (en) 1995-06-07 2001-08-02 Stephen James Brown Modular microprocessor-based health monitoring system
US6968375B1 (en) 1997-03-28 2005-11-22 Health Hero Network, Inc. Networked system for interactive communication and remote monitoring of individuals
US5832448A (en) * 1996-10-16 1998-11-03 Health Hero Network Multiple patient monitoring system for proactive health management
US9215979B2 (en) 1992-11-17 2015-12-22 Robert Bosch Healthcare Systems, Inc. Multi-user remote health monitoring system
US5307263A (en) 1992-11-17 1994-04-26 Raya Systems, Inc. Modular microprocessor-based health monitoring system
US7624028B1 (en) 1992-11-17 2009-11-24 Health Hero Network, Inc. Remote health monitoring and maintenance system
US6330426B2 (en) * 1994-05-23 2001-12-11 Stephen J. Brown System and method for remote education using a memory card
DE4417639A1 (de) * 1994-05-19 1995-11-23 Boehringer Mannheim Gmbh Verfahren zur Bestimmung eines Analyten in einer biologischen Probe
DE19509094A1 (de) * 1995-03-16 1996-09-26 Boehringer Mannheim Gmbh Quantitative Transmissionsspektroskopie unter Verwendung von Probenträgern mit Netzen
US7016713B2 (en) * 1995-08-09 2006-03-21 Inlight Solutions, Inc. Non-invasive determination of direction and rate of change of an analyte
FI960636A (fi) * 1996-02-12 1997-08-13 Nokia Mobile Phones Ltd Menetelmä potilaan terveydentilan valvomiseksi
FI118509B (fi) * 1996-02-12 2007-12-14 Nokia Oyj Menetelmä ja laitteisto potilaan veren glukoosipitoisuuden ennustamiseksi
US5989917A (en) * 1996-02-13 1999-11-23 Selfcare, Inc. Glucose monitor and test strip containers for use in same
EP1579814A3 (en) 1996-05-17 2006-06-14 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US20020010406A1 (en) 1996-05-17 2002-01-24 Douglas Joel S. Methods and apparatus for expressing body fluid from an incision
DE29615910U1 (de) * 1996-08-05 1997-12-04 Lumpert Juerg B Sportgerät mit Datenanzeige für den Benutzer
DE19642316A1 (de) * 1996-10-14 1998-04-23 Dirk Krischenowski Vorrichtung und Verfahren zum Wecken einer schlafenden Person
GB2322444B (en) 1996-10-30 2000-01-19 Mercury Diagnostics Inc Synchronized analyte testing system
JP3394262B2 (ja) 1997-02-06 2003-04-07 セラセンス、インク． 小体積インビトロ被検体センサー
US20050033132A1 (en) * 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
US9155496B2 (en) 1997-03-04 2015-10-13 Dexcom, Inc. Low oxygen in vivo analyte sensor
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US6862465B2 (en) 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US7657297B2 (en) * 2004-05-03 2010-02-02 Dexcom, Inc. Implantable analyte sensor
WO1998041847A1 (en) * 1997-03-14 1998-09-24 Rosemount Analytical Inc. Chemical analyzer with free space communication link
US5961451A (en) * 1997-04-07 1999-10-05 Motorola, Inc. Noninvasive apparatus having a retaining member to retain a removable biosensor
TW357517B (en) * 1997-05-29 1999-05-01 Koji Akai Monitoring system
US6558351B1 (en) 1999-06-03 2003-05-06 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
US7267665B2 (en) * 1999-06-03 2007-09-11 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
US5954643A (en) * 1997-06-09 1999-09-21 Minimid Inc. Insertion set for a transcutaneous sensor
US5948695A (en) 1997-06-17 1999-09-07 Mercury Diagnostics, Inc. Device for determination of an analyte in a body fluid
US7383069B2 (en) * 1997-08-14 2008-06-03 Sensys Medical, Inc. Method of sample control and calibration adjustment for use with a noninvasive analyzer
FI107080B (fi) 1997-10-27 2001-05-31 Nokia Mobile Phones Ltd Mittauslaite
KR100274570B1 (ko) * 1997-11-25 2000-12-15 권석명 화학분석 데이터 처리방법과 그 장치
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6728560B2 (en) 1998-04-06 2004-04-27 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US6721582B2 (en) 1999-04-06 2004-04-13 Argose, Inc. Non-invasive tissue glucose level monitoring
US7899518B2 (en) * 1998-04-06 2011-03-01 Masimo Laboratories, Inc. Non-invasive tissue glucose level monitoring
US6505059B1 (en) 1998-04-06 2003-01-07 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US20020091324A1 (en) * 1998-04-06 2002-07-11 Nikiforos Kollias Non-invasive tissue glucose level monitoring
JP2002510515A (ja) * 1998-04-06 2002-04-09 ザ・ジェネラル・ホスピタル・コーポレイション 非侵襲的組織グルコース・レベル監視
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) * 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) * 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
JP2002514452A (ja) 1998-05-13 2002-05-21 シグナス， インコーポレイテッド 生理学的検体の測定のための信号処理
US7384396B2 (en) * 1998-07-21 2008-06-10 Spectrx Inc. System and method for continuous analyte monitoring
US7077328B2 (en) * 1998-07-31 2006-07-18 Abbott Laboratories Analyte test instrument system including data management system
US6554798B1 (en) 1998-08-18 2003-04-29 Medtronic Minimed, Inc. External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities
US6558320B1 (en) * 2000-01-20 2003-05-06 Medtronic Minimed, Inc. Handheld personal data assistant (PDA) with a medical device and method of using the same
US6248067B1 (en) 1999-02-05 2001-06-19 Minimed Inc. Analyte sensor and holter-type monitor system and method of using the same
US6251260B1 (en) 1998-08-24 2001-06-26 Therasense, Inc. Potentiometric sensors for analytic determination
DE19840965A1 (de) * 1998-09-08 2000-03-09 Disetronic Licensing Ag Vorrichtung zur Selbstverabreichung eines Produktfluids
EP0992963A3 (de) * 1998-10-07 2000-08-30 Alcatel Verfahren zur Signalisierung verkehrsrelevanter Zustandsinformationen
DE19846169A1 (de) 1998-10-07 2000-04-13 Alcatel Sa Verfahren zur Signalisierung verkehrsrelevanter Zustandsinformationen
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6591125B1 (en) 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
DK1413245T3 (da) * 1998-10-08 2011-10-10 Medtronic Minimed Inc Anlæg til overvågning af et kendetegn ved fjernmåling
US20060202859A1 (en) * 1998-10-08 2006-09-14 Mastrototaro John J Telemetered characteristic monitor system and method of using the same
ATE269723T1 (de) * 1998-11-30 2004-07-15 Novo Nordisk As System zur unterstützung einer medizinischen selbstbehandlung,welche eine mehrzahl von schritten umfasst
CA2333328A1 (en) * 1998-12-02 2000-06-08 D. Mark Hamlet Method and apparatus for monitoring anticoagulation levels
US6561978B1 (en) * 1999-02-12 2003-05-13 Cygnus, Inc. Devices and methods for frequent measurement of an analyte present in a biological system
US6424847B1 (en) * 1999-02-25 2002-07-23 Medtronic Minimed, Inc. Glucose monitor calibration methods
US8103325B2 (en) * 1999-03-08 2012-01-24 Tyco Healthcare Group Lp Method and circuit for storing and providing historical physiological data
JP4605906B2 (ja) * 1999-03-08 2011-01-05 ネルコー ピューリタン ベネット エルエルシー 生理学的履歴データ格納および提供するための方法ならびに回路
US6305804B1 (en) 1999-03-25 2001-10-23 Fovioptics, Inc. Non-invasive measurement of blood component using retinal imaging
US20060064323A1 (en) * 1999-04-12 2006-03-23 Alleckson Todd D Data management center for patient monitoring
US6442411B1 (en) * 1999-04-21 2002-08-27 Optix, Lp Method for improving calibration of an instrument for non-invasively measuring constituents in arterial blood
US6669663B1 (en) * 1999-04-30 2003-12-30 Medtronic, Inc. Closed loop medicament pump
CA2388689A1 (en) * 1999-06-17 2000-12-28 Medtronic Minimed, Inc. Characteristic monitor system for use with analyte sensor
EP2322645A1 (en) 1999-06-18 2011-05-18 Abbott Diabetes Care Inc. Mass transport limited in vivo analyte sensor
HK1023262A2 (en) * 1999-07-30 2000-07-28 Chong De Yao Family-use health examination card and its explainer
US20050107676A1 (en) * 2003-03-07 2005-05-19 Acosta George M. Method and apparatus for noninvasive glucose concentration estimation through near-infrared spectroscopy
US7317938B2 (en) * 1999-10-08 2008-01-08 Sensys Medical, Inc. Method of adapting in-vitro models to aid in noninvasive glucose determination
US6527711B1 (en) 1999-10-18 2003-03-04 Bodymedia, Inc. Wearable human physiological data sensors and reporting system therefor
US6616819B1 (en) * 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
US6925393B1 (en) 1999-11-18 2005-08-02 Roche Diagnostics Gmbh System for the extrapolation of glucose concentration
US20030060765A1 (en) * 2000-02-16 2003-03-27 Arthur Campbell Infusion device menu structure and method of using the same
US7890295B2 (en) * 2000-02-23 2011-02-15 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
US6895263B2 (en) * 2000-02-23 2005-05-17 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
US6706159B2 (en) * 2000-03-02 2004-03-16 Diabetes Diagnostics Combined lancet and electrochemical analyte-testing apparatus
US7519406B2 (en) * 2004-04-28 2009-04-14 Sensys Medical, Inc. Noninvasive analyzer sample probe interface method and apparatus
US7606608B2 (en) * 2000-05-02 2009-10-20 Sensys Medical, Inc. Optical sampling interface system for in-vivo measurement of tissue
US20060211931A1 (en) * 2000-05-02 2006-09-21 Blank Thomas B Noninvasive analyzer sample probe interface method and apparatus
US20070179367A1 (en) * 2000-05-02 2007-08-02 Ruchti Timothy L Method and Apparatus for Noninvasively Estimating a Property of an Animal Body Analyte from Spectral Data
US7689437B1 (en) 2000-06-16 2010-03-30 Bodymedia, Inc. System for monitoring health, wellness and fitness
US20060122474A1 (en) * 2000-06-16 2006-06-08 Bodymedia, Inc. Apparatus for monitoring health, wellness and fitness
US6494830B1 (en) * 2000-06-22 2002-12-17 Guidance Interactive Technologies, Inc. Handheld controller for monitoring/using medical parameters
MXPA02012643A (es) * 2000-06-23 2004-09-10 Bodymedia Inc Sistema para monitorear la salud, el estado general y la condicion fisica.
ES2530878T3 (es) * 2000-06-23 2015-03-06 Bodymedia Inc Sistema para monitorizar la salud, el bienestar y el buen estado físico
US20020019752A1 (en) * 2000-06-23 2002-02-14 Isamu Takase System for therapy management and terminal used therefor
US6540675B2 (en) * 2000-06-27 2003-04-01 Rosedale Medical, Inc. Analyte monitor
JP4823443B2 (ja) * 2000-07-14 2011-11-24 日機装株式会社 埋め込み型人工膵臓装置
US6549861B1 (en) 2000-08-10 2003-04-15 Euro-Celtique, S.A. Automated system and method for spectroscopic analysis
US6633772B2 (en) 2000-08-18 2003-10-14 Cygnus, Inc. Formulation and manipulation of databases of analyte and associated values
WO2002015778A1 (en) * 2000-08-18 2002-02-28 Cygnus, Inc. Analyte monitoring device alarm augmentation system
AU2001288292A1 (en) 2000-08-21 2002-03-04 Euroceltique S.A. Near infrared blood glucose monitoring system
US20020026111A1 (en) * 2000-08-28 2002-02-28 Neil Ackerman Methods of monitoring glucose levels in a subject and uses thereof
US6669669B2 (en) * 2001-10-12 2003-12-30 Insulet Corporation Laminated patient infusion device
AU8857501A (en) 2000-09-08 2002-03-22 Insulet Corp Devices, systems and methods for patient infusion
DE60126325T2 (de) 2000-11-09 2007-11-08 Insulet Corp., Beverly Gerät zur transkutanen abgabe von medikamenten
DE10057832C1 (de) 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
DK1347705T3 (da) 2000-12-21 2006-03-27 Insulet Corp Medicinsk apparat til fjernbetjening
EP1381408A4 (en) 2001-02-22 2007-06-13 Insulet Corp MODULAR INFUSION DEVICE AND METHOD
WO2002078512A2 (en) 2001-04-02 2002-10-10 Therasense, Inc. Blood glucose tracking apparatus and methods
WO2002094092A1 (en) * 2001-05-18 2002-11-28 Polymer Technology Systems, Inc. Body fluid test apparatus with detachably mounted portable tester
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7699791B2 (en) 2001-06-12 2010-04-20 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US7749174B2 (en) 2001-06-12 2010-07-06 Pelikan Technologies, Inc. Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge
EP1404232B1 (en) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Blood sampling apparatus and method
DE60238119D1 (de) 2001-06-12 2010-12-09 Pelikan Technologies Inc Elektrisches betätigungselement für eine lanzette
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7316700B2 (en) 2001-06-12 2008-01-08 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US7147615B2 (en) † 2001-06-22 2006-12-12 Baxter International Inc. Needle dislodgement detection
US20030032868A1 (en) * 2001-07-09 2003-02-13 Henning Graskov Method and system for controlling data information between two portable apparatuses
US7257438B2 (en) * 2002-07-23 2007-08-14 Datascope Investment Corp. Patient-worn medical monitoring device
US6702857B2 (en) 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US6544212B2 (en) 2001-07-31 2003-04-08 Roche Diagnostics Corporation Diabetes management system
WO2003014903A2 (en) * 2001-08-09 2003-02-20 Novo Nordisk A/S An operating button with a transparent part for optical communication
US20030072058A1 (en) * 2001-08-09 2003-04-17 Jespersen Soren Kragh Electronic appliance
JP3775263B2 (ja) * 2001-08-10 2006-05-17 ニプロ株式会社 記録媒体およびこの記録媒体を用いた血糖測定システム
US6678542B2 (en) * 2001-08-16 2004-01-13 Optiscan Biomedical Corp. Calibrator configured for use with noninvasive analyte-concentration monitor and employing traditional measurements
US6827702B2 (en) 2001-09-07 2004-12-07 Medtronic Minimed, Inc. Safety limits for closed-loop infusion pump control
US6650915B2 (en) 2001-09-13 2003-11-18 Fovioptics, Inc. Non-invasive measurement of blood analytes using photodynamics
US20050010091A1 (en) * 2003-06-10 2005-01-13 Woods Joe W. Non-invasive measurement of blood glucose using retinal imaging
US20040078028A1 (en) * 2001-11-09 2004-04-22 Flaherty J. Christopher Plunger assembly for patient infusion device
DE10163774A1 (de) 2001-12-22 2003-07-03 Roche Diagnostics Gmbh System mit einem steckbaren Datenübertragungsmodul, welches Daten von einem Analysesystem zu einer Datenverarbeitungseinheit überträgt
US7022072B2 (en) * 2001-12-27 2006-04-04 Medtronic Minimed, Inc. System for monitoring physiological characteristics
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7828728B2 (en) 2003-07-25 2010-11-09 Dexcom, Inc. Analyte sensor
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
DE20213607U1 (de) 2002-02-21 2003-07-03 Hartmann Paul Ag Blutanalysegerät zur Bestimmung eines Analyten
US6830558B2 (en) 2002-03-01 2004-12-14 Insulet Corporation Flow condition sensor assembly for patient infusion device
US6692457B2 (en) 2002-03-01 2004-02-17 Insulet Corporation Flow condition sensor assembly for patient infusion device
US20070149868A1 (en) * 2002-03-08 2007-06-28 Blank Thomas B Method and Apparatus for Photostimulation Enhanced Analyte Property Estimation
US20050054908A1 (en) * 2003-03-07 2005-03-10 Blank Thomas B. Photostimulation method and apparatus in combination with glucose determination
US20050187439A1 (en) * 2003-03-07 2005-08-25 Blank Thomas B. Sampling interface system for in-vivo estimation of tissue analyte concentration
US8504128B2 (en) * 2002-03-08 2013-08-06 Glt Acquisition Corp. Method and apparatus for coupling a channeled sample probe to tissue
US8718738B2 (en) * 2002-03-08 2014-05-06 Glt Acquisition Corp. Method and apparatus for coupling a sample probe with a sample site
EP1499231A4 (en) * 2002-03-08 2007-09-26 Sensys Medical Inc COMPACT DEVICE FOR NONINVASIVE MEASUREMENT OF GLUCOSE BY NEAR-INFRARED SPECTROSCOPY
US6998247B2 (en) * 2002-03-08 2006-02-14 Sensys Medical, Inc. Method and apparatus using alternative site glucose determinations to calibrate and maintain noninvasive and implantable analyzers
US7697966B2 (en) * 2002-03-08 2010-04-13 Sensys Medical, Inc. Noninvasive targeting system method and apparatus
US7027848B2 (en) * 2002-04-04 2006-04-11 Inlight Solutions, Inc. Apparatus and method for non-invasive spectroscopic measurement of analytes in tissue using a matched reference analyte
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7481776B2 (en) 2002-04-19 2009-01-27 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US7232451B2 (en) * 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9848815B2 (en) * 2002-04-22 2017-12-26 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
US6656158B2 (en) 2002-04-23 2003-12-02 Insulet Corporation Dispenser for patient infusion device
US6656159B2 (en) 2002-04-23 2003-12-02 Insulet Corporation Dispenser for patient infusion device
US6960192B1 (en) 2002-04-23 2005-11-01 Insulet Corporation Transcutaneous fluid delivery system
US20050238507A1 (en) * 2002-04-23 2005-10-27 Insulet Corporation Fluid delivery device
US20040153032A1 (en) * 2002-04-23 2004-08-05 Garribotto John T. Dispenser for patient infusion device
JP3854190B2 (ja) * 2002-04-26 2006-12-06 株式会社ジェイテクト モータ制御装置
US6801041B2 (en) * 2002-05-14 2004-10-05 Abbott Laboratories Sensor having electrode for determining the rate of flow of a fluid
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
GB2389419B (en) * 2002-06-05 2006-02-22 Diabetes Diagnostics Inc Analyte testing device
US6723072B2 (en) 2002-06-06 2004-04-20 Insulet Corporation Plunger assembly for patient infusion device
US7018360B2 (en) * 2002-07-16 2006-03-28 Insulet Corporation Flow restriction system and method for patient infusion device
US20040068230A1 (en) 2002-07-24 2004-04-08 Medtronic Minimed, Inc. System for providing blood glucose measurements to an infusion device
US7278983B2 (en) 2002-07-24 2007-10-09 Medtronic Minimed, Inc. Physiological monitoring device for controlling a medication infusion device
US20070100666A1 (en) * 2002-08-22 2007-05-03 Stivoric John M Devices and systems for contextual and physiological-based detection, monitoring, reporting, entertainment, and control of other devices
US7020508B2 (en) 2002-08-22 2006-03-28 Bodymedia, Inc. Apparatus for detecting human physiological and contextual information
US6895264B2 (en) * 2002-08-26 2005-05-17 Fovioptics Inc. Non-invasive psychophysical measurement of glucose using photodynamics
JP2005537891A (ja) * 2002-09-10 2005-12-15 ユーロ−セルティーク エス．エイ． 血液成分の非侵襲的測定のための装置及び方法
US7144384B2 (en) * 2002-09-30 2006-12-05 Insulet Corporation Dispenser components and methods for patient infusion device
US7128727B2 (en) * 2002-09-30 2006-10-31 Flaherty J Christopher Components and methods for patient infusion device
US7727181B2 (en) * 2002-10-09 2010-06-01 Abbott Diabetes Care Inc. Fluid delivery device with autocalibration
US20090177068A1 (en) * 2002-10-09 2009-07-09 Stivoric John M Method and apparatus for providing derived glucose information utilizing physiological and/or contextual parameters
US7993108B2 (en) 2002-10-09 2011-08-09 Abbott Diabetes Care Inc. Variable volume, shape memory actuated insulin dispensing pump
CA2817028A1 (en) * 2002-10-09 2004-04-22 Bodymedia, Inc. Method and apparatus for auto journaling of continuous or discrete body states utilizing physiological and/or contextual parameters
EP2386758A1 (en) 2002-10-09 2011-11-16 Abbott Diabetes Care Inc. A method of pumping a predetermined dose of a medical fluid
DE10248682A1 (de) * 2002-10-18 2004-05-13 T-Mobile Deutschland Gmbh Tragbares Diagnosegerät und damit verbundenes Verfahren zur Übertragung der Diagnosedaten
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US20040116866A1 (en) * 2002-12-17 2004-06-17 William Gorman Skin attachment apparatus and method for patient infusion device
US20040122353A1 (en) * 2002-12-19 2004-06-24 Medtronic Minimed, Inc. Relay device for transferring information between a sensor system and a fluid delivery system
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
US7212925B2 (en) * 2003-01-21 2007-05-01 Bayer Healthcare Llc. Calibration data entry system for a test instrument
WO2004069164A2 (en) * 2003-01-30 2004-08-19 Euro Celtique Sa Wireless blood glucose monitoring system
US20050159656A1 (en) * 2003-03-07 2005-07-21 Hockersmith Linda J. Method and apparatus for presentation of noninvasive glucose concentration information
US7052652B2 (en) 2003-03-24 2006-05-30 Rosedale Medical, Inc. Analyte concentration detection devices and methods
US8718943B2 (en) * 2003-04-01 2014-05-06 Abbott Diabetes Care Inc. Method and device for utilizing analyte levels to assist in the treatment of diabetes
US7587287B2 (en) 2003-04-04 2009-09-08 Abbott Diabetes Care Inc. Method and system for transferring analyte test data
US7134999B2 (en) * 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
US20050182366A1 (en) * 2003-04-18 2005-08-18 Insulet Corporation Method For Visual Output Verification
US7182738B2 (en) 2003-04-23 2007-02-27 Marctec, Llc Patient monitoring apparatus and method for orthosis and other devices
US7679407B2 (en) 2003-04-28 2010-03-16 Abbott Diabetes Care Inc. Method and apparatus for providing peak detection circuitry for data communication systems
US7399276B1 (en) 2003-05-08 2008-07-15 Health Hero Network, Inc. Remote health monitoring system
AU2003902187A0 (en) * 2003-05-08 2003-05-22 Aimedics Pty Ltd Patient monitor
AU2004236368B2 (en) * 2003-05-08 2011-08-04 University Of Technology, Sydney Patient moniter
JP2004343275A (ja) * 2003-05-14 2004-12-02 Murata Mach Ltd 画像処理システム及びスキャナ装置
US7875293B2 (en) * 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
WO2004103170A1 (en) * 2003-05-22 2004-12-02 Novo Nordisk A/S A glucose measuring device
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8066639B2 (en) * 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US8071028B2 (en) * 2003-06-12 2011-12-06 Abbott Diabetes Care Inc. Method and apparatus for providing power management in data communication systems
US7695239B2 (en) * 2003-07-14 2010-04-13 Fortrend Engineering Corporation End effector gripper arms having corner grippers which reorient reticle during transfer
US20050051427A1 (en) * 2003-07-23 2005-03-10 Brauker James H. Rolled electrode array and its method for manufacture
US7761130B2 (en) 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7074307B2 (en) 2003-07-25 2006-07-11 Dexcom, Inc. Electrode systems for electrochemical sensors
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
EP1648298A4 (en) 2003-07-25 2010-01-13 Dexcom Inc OXYGEN-IMPROVED MEMBRANE SYSTEMS FOR IMPLANTABLE DEVICES
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US7519408B2 (en) * 2003-11-19 2009-04-14 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US20070208245A1 (en) * 2003-08-01 2007-09-06 Brauker James H Transcutaneous analyte sensor
US20080119703A1 (en) * 2006-10-04 2008-05-22 Mark Brister Analyte sensor
US8626257B2 (en) 2003-08-01 2014-01-07 Dexcom, Inc. Analyte sensor
US20100168542A1 (en) 2003-08-01 2010-07-01 Dexcom, Inc. System and methods for processing analyte sensor data
US6931327B2 (en) * 2003-08-01 2005-08-16 Dexcom, Inc. System and methods for processing analyte sensor data
US7959569B2 (en) 2003-08-01 2011-06-14 Dexcom, Inc. System and methods for processing analyte sensor data
US7494465B2 (en) 2004-07-13 2009-02-24 Dexcom, Inc. Transcutaneous analyte sensor
US9135402B2 (en) 2007-12-17 2015-09-15 Dexcom, Inc. Systems and methods for processing sensor data
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US8886273B2 (en) 2003-08-01 2014-11-11 Dexcom, Inc. Analyte sensor
US8845536B2 (en) 2003-08-01 2014-09-30 Dexcom, Inc. Transcutaneous analyte sensor
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US7306641B2 (en) * 2003-09-12 2007-12-11 Hewlett-Packard Development Company, L.P. Integral fuel cartridge and filter
US20070234300A1 (en) * 2003-09-18 2007-10-04 Leake David W Method and Apparatus for Performing State-Table Driven Regression Testing
US20050065760A1 (en) * 2003-09-23 2005-03-24 Robert Murtfeldt Method for advising patients concerning doses of insulin
DE10343863A1 (de) * 2003-09-23 2005-04-14 Roche Diagnostics Gmbh Verfahren und Gerät zur laufenden Überwachung der Konzentration eines Analyten
US20050070847A1 (en) * 2003-09-29 2005-03-31 Van Erp Wilhelmus Petrus Martinus Maria Rapid-exchange balloon catheter with hypotube shaft
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
US20050278194A1 (en) * 2003-10-07 2005-12-15 Holland Geoffrey N Medication management system
US20060089855A1 (en) * 2003-10-07 2006-04-27 Holland Geoffrey N Medication management system
US20060089854A1 (en) * 2003-10-07 2006-04-27 Holland Geoffrey N Medication management system
US7895053B2 (en) * 2003-10-07 2011-02-22 Hospira, Inc. Medication management system
US8065161B2 (en) 2003-11-13 2011-11-22 Hospira, Inc. System for maintaining drug information and communicating with medication delivery devices
US7490021B2 (en) * 2003-10-07 2009-02-10 Hospira, Inc. Method for adjusting pump screen brightness
US9123077B2 (en) 2003-10-07 2015-09-01 Hospira, Inc. Medication management system
US20060100907A1 (en) * 2003-10-07 2006-05-11 Holland Geoffrey N Medication management system
EP1680014A4 (en) 2003-10-14 2009-01-21 Pelikan Technologies Inc METHOD AND APPARATUS PROVIDING A VARIABLE USER INTERFACE
US20050090607A1 (en) * 2003-10-28 2005-04-28 Dexcom, Inc. Silicone composition for biocompatible membrane
JP2007512588A (ja) * 2003-10-29 2007-05-17 ノボ・ノルデイスク・エー／エス 医療助言システム
US20050096518A1 (en) * 2003-10-31 2005-05-05 Yu-Hong Chang Biological test system
US7299082B2 (en) * 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
USD914881S1 (en) 2003-11-05 2021-03-30 Abbott Diabetes Care Inc. Analyte sensor electronic mount
JP4704351B2 (ja) * 2003-11-06 2011-06-15 ライフスキャン・インコーポレイテッド イベント通知手段を備えた薬剤導入ペン
WO2005046441A2 (en) * 2003-11-06 2005-05-26 Sensys Medical, Inc. Method of adapting in-vitro models to aid in noninvasive glucose determination
US8221332B2 (en) * 2003-11-12 2012-07-17 Facet Technologies, Llc Multi-lancet cartridge and lancing device
US20080082117A1 (en) * 2003-11-12 2008-04-03 Facet Technologies, Llc Lancing device
US20050154410A1 (en) * 2003-11-12 2005-07-14 Conway William E. Lancing device and multi-lancet cartridge
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8425417B2 (en) 2003-12-05 2013-04-23 Dexcom, Inc. Integrated device for continuous in vivo analyte detection and simultaneous control of an infusion device
US8287453B2 (en) 2003-12-05 2012-10-16 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
WO2005057168A2 (en) 2003-12-05 2005-06-23 Dexcom, Inc. Calibration techniques for a continuous analyte sensor
US8364230B2 (en) * 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8425416B2 (en) * 2006-10-04 2013-04-23 Dexcom, Inc. Analyte sensor
WO2005057175A2 (en) 2003-12-09 2005-06-23 Dexcom, Inc. Signal processing for continuous analyte sensor
US7384397B2 (en) † 2003-12-30 2008-06-10 Medtronic Minimed, Inc. System and method for sensor recalibration
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
WO2005089103A2 (en) 2004-02-17 2005-09-29 Therasense, Inc. Method and system for providing data communication in continuous glucose monitoring and management system
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
CA2460898A1 (en) * 2004-03-09 2005-09-09 James Samsoondar Apparatus and method for combining in vivo and in vitro testing
CA2560323C (en) * 2004-03-22 2014-01-07 Bodymedia, Inc. Non-invasive temperature monitoring device
US20060258918A1 (en) * 2004-04-14 2006-11-16 Oculir, Inc. Combination Analyte Measurement Device and Method of Use
US20060258920A1 (en) * 2004-04-14 2006-11-16 Oculir, Inc. Non-Invasive Analyte Measurement Glasses and Method of Use
JP4944770B2 (ja) 2004-04-16 2012-06-06 ファセット・テクノロジーズ・エルエルシー 穿刺装置用のキャップ変位機構及びマルチランセットカートリッジ
DE102004020160A1 (de) 2004-04-24 2005-11-10 Roche Diagnostics Gmbh Verfahren und Vorrichtung zum Überwachen einer Konzentration eines Analyten im lebenden Körper eines Menschen oder Tieres
US20080033275A1 (en) * 2004-04-28 2008-02-07 Blank Thomas B Method and Apparatus for Sample Probe Movement Control
US8868147B2 (en) * 2004-04-28 2014-10-21 Glt Acquisition Corp. Method and apparatus for controlling positioning of a noninvasive analyzer sample probe
WO2005106446A1 (ja) * 2004-04-30 2005-11-10 Matsushita Electric Industrial Co., Ltd. 血糖値計測装置
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
US8277713B2 (en) 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
US20050245799A1 (en) * 2004-05-03 2005-11-03 Dexcom, Inc. Implantable analyte sensor
US7242480B2 (en) * 2004-05-14 2007-07-10 Medeikon Corporation Low coherence interferometry for detecting and characterizing plaques
US7190464B2 (en) * 2004-05-14 2007-03-13 Medeikon Corporation Low coherence interferometry for detecting and characterizing plaques
US7327463B2 (en) 2004-05-14 2008-02-05 Medrikon Corporation Low coherence interferometry utilizing magnitude
US7474408B2 (en) * 2004-05-14 2009-01-06 Medeikon Corporation Low coherence interferometry utilizing phase
US20050254059A1 (en) * 2004-05-14 2005-11-17 Alphonse Gerard A Low coherence interferometric system for optical metrology
US7184148B2 (en) 2004-05-14 2007-02-27 Medeikon Corporation Low coherence interferometry utilizing phase
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc METHOD AND APPARATUS FOR MANUFACTURING A DEVICE FOR SAMPLING LIQUIDS
US20060010098A1 (en) 2004-06-04 2006-01-12 Goodnow Timothy T Diabetes care host-client architecture and data management system
DE602005017492D1 (de) * 2004-06-14 2009-12-17 Eyesense Ag Kombiniertes gerät zum messen von blutzucker aus augenflüssigkeit
US20050283380A1 (en) * 2004-06-18 2005-12-22 Garduno Ramon S Delivery service for a health management system
JP2008504893A (ja) * 2004-06-30 2008-02-21 ファセット・テクノロジーズ・エルエルシー 穿刺装置及びマルチランセットカートリッジ
US8886272B2 (en) 2004-07-13 2014-11-11 Dexcom, Inc. Analyte sensor
US20080242961A1 (en) * 2004-07-13 2008-10-02 Dexcom, Inc. Transcutaneous analyte sensor
US20060270922A1 (en) * 2004-07-13 2006-11-30 Brauker James H Analyte sensor
US20060020192A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
US7783333B2 (en) 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
GB0421793D0 (en) * 2004-10-01 2004-11-03 Univ Aston Sensing device
US20080171913A1 (en) * 2004-11-15 2008-07-17 Novo Nordisk A/S Method and Apparatus for Monitoring Long Term and Short Term Effects of a Treatment
WO2006066038A2 (en) * 2004-12-17 2006-06-22 Bayer Healthcare Llc Analyte test device having a trend-indicating display
AT7892U3 (de) * 2004-12-21 2006-08-15 Evelyne Lorenz Elektronisches diabetikertagebuch
US8613703B2 (en) * 2007-05-31 2013-12-24 Abbott Diabetes Care Inc. Insertion devices and methods
US7883464B2 (en) 2005-09-30 2011-02-08 Abbott Diabetes Care Inc. Integrated transmitter unit and sensor introducer mechanism and methods of use
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US8333714B2 (en) 2006-09-10 2012-12-18 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
WO2006070199A1 (en) * 2004-12-29 2006-07-06 Lifescan Scotland Limited An analyte test meter having a test sensor port
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US9636450B2 (en) 2007-02-19 2017-05-02 Udo Hoss Pump system modular components for delivering medication and analyte sensing at seperate insertion sites
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US7731657B2 (en) 2005-08-30 2010-06-08 Abbott Diabetes Care Inc. Analyte sensor introducer and methods of use
US9743862B2 (en) 2011-03-31 2017-08-29 Abbott Diabetes Care Inc. Systems and methods for transcutaneously implanting medical devices
CN101137320B (zh) 2004-12-29 2012-10-03 生命扫描苏格兰有限公司 将数据输入到分析物测试装置的方法
US20090105569A1 (en) 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US8571624B2 (en) 2004-12-29 2013-10-29 Abbott Diabetes Care Inc. Method and apparatus for mounting a data transmission device in a communication system
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
ITBO20050002A1 (it) * 2005-01-04 2006-07-05 Giacomo Vespasiani Metodo e sistema per la gestione interattiva di dati relativi ad una terapia insulinica in autocontrollo per un paziente diabetico
US7547281B2 (en) 2005-02-01 2009-06-16 Medtronic Minimed, Inc. Algorithm sensor augmented bolus estimator for semi-closed loop infusion system
EP1688085A1 (en) * 2005-02-02 2006-08-09 Disetronic Licensing AG Ambulatory medical device and method of communication between medical devices
US20060178633A1 (en) * 2005-02-03 2006-08-10 Insulet Corporation Chassis for fluid delivery device
US7545272B2 (en) * 2005-02-08 2009-06-09 Therasense, Inc. RF tag on test strips, test strip vials and boxes
US20060217602A1 (en) * 2005-03-04 2006-09-28 Alan Abul-Haj Method and apparatus for noninvasive targeting
US20090076360A1 (en) 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
ATE412364T1 (de) * 2005-03-15 2008-11-15 Hoffmann La Roche Verfahren und system zur untersuchung des glucosestoffwechsels
CN101180093B (zh) 2005-03-21 2012-07-18 雅培糖尿病护理公司 用于提供结合的药剂输液以及分析物监测系统的方法和系统
US8744546B2 (en) 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
US20100245803A1 (en) * 2005-04-12 2010-09-30 Chromedx Inc. Blood sample holder for spectroscopic analysis
US8206650B2 (en) * 2005-04-12 2012-06-26 Chromedx Inc. Joint-diagnostic spectroscopic and biosensor meter
CA2517299A1 (en) * 2005-08-26 2007-02-26 Chromedx Inc. Hollow needle assembly
CA2507323A1 (en) * 2005-05-13 2006-11-13 Chromedx Inc. Diagnostic whole blood and plasma apparatus
US8060174B2 (en) 2005-04-15 2011-11-15 Dexcom, Inc. Analyte sensing biointerface
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US7768408B2 (en) 2005-05-17 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing data management in data monitoring system
US7552240B2 (en) * 2005-05-23 2009-06-23 International Business Machines Corporation Method for user space operations for direct I/O between an application instance and an I/O adapter
US7620437B2 (en) 2005-06-03 2009-11-17 Abbott Diabetes Care Inc. Method and apparatus for providing rechargeable power in data monitoring and management systems
US20060281187A1 (en) 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
US9504394B2 (en) * 2005-07-28 2016-11-29 The General Hospital Corporation Electro-optical system, apparatus, and method for ambulatory monitoring
CN101365374B (zh) 2005-08-31 2011-11-16 弗吉尼亚大学专利基金委员会 改善连续式葡萄糖传感器的准确度
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
US8801631B2 (en) 2005-09-30 2014-08-12 Intuity Medical, Inc. Devices and methods for facilitating fluid transport
US7756561B2 (en) 2005-09-30 2010-07-13 Abbott Diabetes Care Inc. Method and apparatus for providing rechargeable power in data monitoring and management systems
US8880138B2 (en) 2005-09-30 2014-11-04 Abbott Diabetes Care Inc. Device for channeling fluid and methods of use
EP3461406A1 (en) 2005-09-30 2019-04-03 Intuity Medical, Inc. Multi-site body fluid sampling and analysis cartridge
US7583190B2 (en) 2005-10-31 2009-09-01 Abbott Diabetes Care Inc. Method and apparatus for providing data communication in data monitoring and management systems
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
DE102006051562A1 (de) * 2005-11-15 2007-05-16 Weinmann G Geraete Med Signalgeber sowie Regelkreis für eine physiologische Variable
US20070118030A1 (en) * 2005-11-22 2007-05-24 Isense Corporation Method and apparatus for analyte data telemetry
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
EP1968432A4 (en) 2005-12-28 2009-10-21 Abbott Diabetes Care Inc INTRODUCTION OF A MEDICAL DEVICE
US20080015422A1 (en) * 2005-12-29 2008-01-17 Guidance Interactive Healthcare, Inc. Combined peripheral and health monitoring devices
US20070179356A1 (en) * 2005-12-29 2007-08-02 Guidance Interactive Healthcare, Inc. Programmable devices, systems and methods for encouraging the monitoring of medical parameters
US8114269B2 (en) 2005-12-30 2012-02-14 Medtronic Minimed, Inc. System and method for determining the point of hydration and proper time to apply potential to a glucose sensor
US8114268B2 (en) * 2005-12-30 2012-02-14 Medtronic Minimed, Inc. Method and system for remedying sensor malfunctions detected by electrochemical impedance spectroscopy
US7985330B2 (en) 2005-12-30 2011-07-26 Medtronic Minimed, Inc. Method and system for detecting age, hydration, and functional states of sensors using electrochemical impedance spectroscopy
US9757061B2 (en) 2006-01-17 2017-09-12 Dexcom, Inc. Low oxygen in vivo analyte sensor
US7736310B2 (en) 2006-01-30 2010-06-15 Abbott Diabetes Care Inc. On-body medical device securement
US8344966B2 (en) 2006-01-31 2013-01-01 Abbott Diabetes Care Inc. Method and system for providing a fault tolerant display unit in an electronic device
US7826879B2 (en) 2006-02-28 2010-11-02 Abbott Diabetes Care Inc. Analyte sensors and methods of use
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
EP1991110B1 (en) 2006-03-09 2018-11-07 DexCom, Inc. Systems and methods for processing analyte sensor data
EP1837787A1 (en) * 2006-03-24 2007-09-26 GlucoTel Scientific Inc. Telemedical method and device for the calibration of measured values
US8473022B2 (en) 2008-01-31 2013-06-25 Abbott Diabetes Care Inc. Analyte sensor with time lag compensation
US9675290B2 (en) 2012-10-30 2017-06-13 Abbott Diabetes Care Inc. Sensitivity calibration of in vivo sensors used to measure analyte concentration
US9392969B2 (en) 2008-08-31 2016-07-19 Abbott Diabetes Care Inc. Closed loop control and signal attenuation detection
US7653425B2 (en) 2006-08-09 2010-01-26 Abbott Diabetes Care Inc. Method and system for providing calibration of an analyte sensor in an analyte monitoring system
US9326709B2 (en) 2010-03-10 2016-05-03 Abbott Diabetes Care Inc. Systems, devices and methods for managing glucose levels
US7630748B2 (en) 2006-10-25 2009-12-08 Abbott Diabetes Care Inc. Method and system for providing analyte monitoring
US8374668B1 (en) 2007-10-23 2013-02-12 Abbott Diabetes Care Inc. Analyte sensor with lag compensation
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US7801582B2 (en) 2006-03-31 2010-09-21 Abbott Diabetes Care Inc. Analyte monitoring and management system and methods therefor
US8478557B2 (en) 2009-07-31 2013-07-02 Abbott Diabetes Care Inc. Method and apparatus for providing analyte monitoring system calibration accuracy
US8219173B2 (en) 2008-09-30 2012-07-10 Abbott Diabetes Care Inc. Optimizing analyte sensor calibration
US7618369B2 (en) 2006-10-02 2009-11-17 Abbott Diabetes Care Inc. Method and system for dynamically updating calibration parameters for an analyte sensor
US8346335B2 (en) 2008-03-28 2013-01-01 Abbott Diabetes Care Inc. Analyte sensor calibration management
US8224415B2 (en) 2009-01-29 2012-07-17 Abbott Diabetes Care Inc. Method and device for providing offset model based calibration for analyte sensor
US8140312B2 (en) 2007-05-14 2012-03-20 Abbott Diabetes Care Inc. Method and system for determining analyte levels
US7488930B2 (en) * 2006-06-02 2009-02-10 Medeikon Corporation Multi-channel low coherence interferometer
US20080071158A1 (en) 2006-06-07 2008-03-20 Abbott Diabetes Care, Inc. Analyte monitoring system and method
KR100735898B1 (ko) * 2006-08-25 2007-07-04 한국기계연구원 휴대용 미세 혈액 분리기
US8449464B2 (en) 2006-10-04 2013-05-28 Dexcom, Inc. Analyte sensor
US8447376B2 (en) 2006-10-04 2013-05-21 Dexcom, Inc. Analyte sensor
US8478377B2 (en) 2006-10-04 2013-07-02 Dexcom, Inc. Analyte sensor
US8275438B2 (en) 2006-10-04 2012-09-25 Dexcom, Inc. Analyte sensor
US8298142B2 (en) 2006-10-04 2012-10-30 Dexcom, Inc. Analyte sensor
US8562528B2 (en) 2006-10-04 2013-10-22 Dexcom, Inc. Analyte sensor
US7831287B2 (en) * 2006-10-04 2010-11-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
WO2008057729A2 (en) 2006-10-16 2008-05-15 Hospira, Inc. System and method for comparing and utilizing activity information and configuration information from mulitple device management systems
US20080092638A1 (en) * 2006-10-19 2008-04-24 Bayer Healthcare Llc Wireless analyte monitoring system
CN102772212A (zh) 2006-10-26 2012-11-14 雅培糖尿病护理公司 检测被分析物传感器中的信号衰减的方法、设备和系统
US8579853B2 (en) 2006-10-31 2013-11-12 Abbott Diabetes Care Inc. Infusion devices and methods
EP1918837A1 (en) 2006-10-31 2008-05-07 F. Hoffmann-La Roche AG Method for processing a chronological sequence of measurements of a time dependent parameter
US20080119705A1 (en) * 2006-11-17 2008-05-22 Medtronic Minimed, Inc. Systems and Methods for Diabetes Management Using Consumer Electronic Devices
US7946985B2 (en) * 2006-12-29 2011-05-24 Medtronic Minimed, Inc. Method and system for providing sensor redundancy
ES2683852T3 (es) 2007-01-23 2018-09-28 Ascensia Diabetes Care Holdings Ag Dispositivo de ensayo de analito
US8121857B2 (en) 2007-02-15 2012-02-21 Abbott Diabetes Care Inc. Device and method for automatic data acquisition and/or detection
US20080199894A1 (en) 2007-02-15 2008-08-21 Abbott Diabetes Care, Inc. Device and method for automatic data acquisition and/or detection
US20090006457A1 (en) * 2007-02-16 2009-01-01 Stivoric John M Lifeotypes
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US20080208509A1 (en) * 2007-02-27 2008-08-28 Bayer Healthcare, Llc System and method for graphically plotting and displaying analyte concentration data on a calendar
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
WO2008128210A1 (en) 2007-04-14 2008-10-23 Abbott Diabetes Care, Inc. Method and apparatus for providing data processing and control in medical communication system
CA2683953C (en) 2007-04-14 2016-08-02 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
EP2146624B1 (en) 2007-04-14 2020-03-25 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
WO2009096992A1 (en) 2007-04-14 2009-08-06 Abbott Diabetes Care, Inc. Method and apparatus for providing data processing and control in medical communication system
CA2683962C (en) 2007-04-14 2017-06-06 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
CA2683721C (en) * 2007-04-14 2017-05-23 Abbott Diabetes Care Inc. Method and apparatus for providing dynamic multi-stage signal amplification in a medical device
US20080269714A1 (en) 2007-04-25 2008-10-30 Medtronic Minimed, Inc. Closed loop/semi-closed loop therapy modification system
US20080274552A1 (en) * 2007-05-04 2008-11-06 Brian Guthrie Dynamic Information Transfer
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8260558B2 (en) 2007-05-14 2012-09-04 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8444560B2 (en) 2007-05-14 2013-05-21 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US7996158B2 (en) 2007-05-14 2011-08-09 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8560038B2 (en) 2007-05-14 2013-10-15 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8239166B2 (en) 2007-05-14 2012-08-07 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8103471B2 (en) 2007-05-14 2012-01-24 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US10002233B2 (en) 2007-05-14 2018-06-19 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US9125548B2 (en) 2007-05-14 2015-09-08 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8600681B2 (en) 2007-05-14 2013-12-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US20200037874A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US20080306444A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
AU2008265541B2 (en) 2007-06-21 2014-07-17 Abbott Diabetes Care, Inc. Health management devices and methods
US8160900B2 (en) 2007-06-29 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
US20100094326A1 (en) * 2007-07-05 2010-04-15 Blackrock Kelso Capital Corporation Multi-lancet cartridge and lancing device
US8834366B2 (en) 2007-07-31 2014-09-16 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor calibration
US7768386B2 (en) * 2007-07-31 2010-08-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US20090036759A1 (en) * 2007-08-01 2009-02-05 Ault Timothy E Collapsible noninvasive analyzer method and apparatus
CN101808680B (zh) * 2007-08-01 2014-07-02 F·霍夫曼-拉罗氏股份公司 带有用于监测和控制流体输送的器件的便携式输注设备
EP2227132B1 (en) 2007-10-09 2023-03-08 DexCom, Inc. Integrated insulin delivery system with continuous glucose sensor
US8409093B2 (en) 2007-10-23 2013-04-02 Abbott Diabetes Care Inc. Assessing measures of glycemic variability
US8377031B2 (en) * 2007-10-23 2013-02-19 Abbott Diabetes Care Inc. Closed loop control system with safety parameters and methods
US8216138B1 (en) 2007-10-23 2012-07-10 Abbott Diabetes Care Inc. Correlation of alternative site blood and interstitial fluid glucose concentrations to venous glucose concentration
US8417312B2 (en) 2007-10-25 2013-04-09 Dexcom, Inc. Systems and methods for processing sensor data
US7783442B2 (en) * 2007-10-31 2010-08-24 Medtronic Minimed, Inc. System and methods for calibrating physiological characteristic sensors
US9022931B2 (en) 2007-12-10 2015-05-05 Bayer Healthcare Llc Interface for a health measurement and monitoring system
EP2229093B1 (en) 2007-12-10 2018-04-25 Ascensia Diabetes Care Holdings AG Rapid charging and power management of a battery-powered fluid analyte meter
US8290559B2 (en) 2007-12-17 2012-10-16 Dexcom, Inc. Systems and methods for processing sensor data
US9026370B2 (en) 2007-12-18 2015-05-05 Hospira, Inc. User interface improvements for medical devices
US20090164239A1 (en) 2007-12-19 2009-06-25 Abbott Diabetes Care, Inc. Dynamic Display Of Glucose Information
EP2107367B1 (en) * 2008-02-07 2020-07-15 ARKRAY, Inc. Code readout device and data-gathering system using the same
WO2009105337A2 (en) * 2008-02-20 2009-08-27 Dexcom, Inc. Continuous medicament sensor system for in vivo use
CA2715628A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US8396528B2 (en) 2008-03-25 2013-03-12 Dexcom, Inc. Analyte sensor
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
EP3659628A1 (en) 2008-04-10 2020-06-03 Abbott Diabetes Care, Inc. Method and system for sterilizing an analyte sensor
EP2265324B1 (en) 2008-04-11 2015-01-28 Sanofi-Aventis Deutschland GmbH Integrated analyte measurement system
JP5816080B2 (ja) 2008-05-30 2015-11-17 インテュイティ メディカル インコーポレイテッド 体液採取装置及び採取部位インターフェイス
US7826382B2 (en) 2008-05-30 2010-11-02 Abbott Diabetes Care Inc. Close proximity communication device and methods
US8924159B2 (en) 2008-05-30 2014-12-30 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US8591410B2 (en) 2008-05-30 2013-11-26 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
JP2011522616A (ja) * 2008-06-04 2011-08-04 セブンス センス バイオシステムズ，インコーポレーテッド シングルステップ診断のための組成物および方法
US20090305317A1 (en) * 2008-06-05 2009-12-10 Brauer Jacob S User interface for testing device
ES2907152T3 (es) 2008-06-06 2022-04-22 Intuity Medical Inc Medidor de glucosa en sangre y método de funcionamiento
US9636051B2 (en) 2008-06-06 2017-05-02 Intuity Medical, Inc. Detection meter and mode of operation
US8876755B2 (en) 2008-07-14 2014-11-04 Abbott Diabetes Care Inc. Closed loop control system interface and methods
EP2149957B1 (en) * 2008-07-30 2017-06-14 Harman Becker Automotive Systems GmbH Priority based power distribution arrangement
SG193205A1 (en) 2008-08-15 2013-09-30 Lifescan Scotland Ltd Analyte testing method and system
US7959598B2 (en) 2008-08-20 2011-06-14 Asante Solutions, Inc. Infusion pump systems and methods
CA2735147A1 (en) * 2008-08-28 2010-03-04 Isense Corporation Method and system for communication between wireless devices
DE102008044895B4 (de) * 2008-08-29 2018-02-22 Astrium Gmbh Signal-Verzweigung zur Verwendung in einem Kommunikationssystem
US9943644B2 (en) 2008-08-31 2018-04-17 Abbott Diabetes Care Inc. Closed loop control with reference measurement and methods thereof
US8734422B2 (en) 2008-08-31 2014-05-27 Abbott Diabetes Care Inc. Closed loop control with improved alarm functions
US20100057040A1 (en) 2008-08-31 2010-03-04 Abbott Diabetes Care, Inc. Robust Closed Loop Control And Methods
US8622988B2 (en) 2008-08-31 2014-01-07 Abbott Diabetes Care Inc. Variable rate closed loop control and methods
US8560039B2 (en) 2008-09-19 2013-10-15 Dexcom, Inc. Particle-containing membrane and particulate electrode for analyte sensors
US8986208B2 (en) 2008-09-30 2015-03-24 Abbott Diabetes Care Inc. Analyte sensor sensitivity attenuation mitigation
US9326707B2 (en) 2008-11-10 2016-05-03 Abbott Diabetes Care Inc. Alarm characterization for analyte monitoring devices and systems
US8437821B2 (en) * 2009-01-06 2013-05-07 Panasonic Corporation Non-invasive body information measurement apparatus
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US8560082B2 (en) 2009-01-30 2013-10-15 Abbott Diabetes Care Inc. Computerized determination of insulin pump therapy parameters using real time and retrospective data processing
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
US20120277629A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systems and methods for collection and/or manipulation of blood spots or other bodily fluids
WO2012018486A2 (en) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
WO2010101620A2 (en) 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Systems and methods for creating and using suction blisters or other pooled regions of fluid within the skin
WO2010111660A1 (en) 2009-03-27 2010-09-30 Dexcom, Inc. Methods and systems for promoting glucose management
US8497777B2 (en) 2009-04-15 2013-07-30 Abbott Diabetes Care Inc. Analyte monitoring system having an alert
EP2419015A4 (en) 2009-04-16 2014-08-20 Abbott Diabetes Care Inc ANALYTE SENSOR CALIBRATION MANAGEMENT
US8271106B2 (en) 2009-04-17 2012-09-18 Hospira, Inc. System and method for configuring a rule set for medical event management and responses
WO2010127050A1 (en) 2009-04-28 2010-11-04 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US8467972B2 (en) 2009-04-28 2013-06-18 Abbott Diabetes Care Inc. Closed loop blood glucose control algorithm analysis
WO2010127187A1 (en) 2009-04-29 2010-11-04 Abbott Diabetes Care Inc. Method and system for providing data communication in continuous glucose monitoring and management system
EP2425209A4 (en) 2009-04-29 2013-01-09 Abbott Diabetes Care Inc METHOD AND SYSTEM FOR REAL-TIME CALIBRATION OF AN ANALYTICAL SENSOR WITH RETROACTIVE FILLING
WO2010138856A1 (en) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
US8613892B2 (en) 2009-06-30 2013-12-24 Abbott Diabetes Care Inc. Analyte meter with a moveable head and methods of using the same
LT3689237T (lt) 2009-07-23 2021-09-27 Abbott Diabetes Care, Inc. Nuolatinio analitės matavimo sistema ir gamybos būdas
WO2011011739A2 (en) 2009-07-23 2011-01-27 Abbott Diabetes Care Inc. Real time management of data relating to physiological control of glucose levels
DK3988470T3 (da) 2009-08-31 2023-08-28 Abbott Diabetes Care Inc Visningsindretninger til en medicinsk indretning
US9314195B2 (en) 2009-08-31 2016-04-19 Abbott Diabetes Care Inc. Analyte signal processing device and methods
JP5795584B2 (ja) 2009-08-31 2015-10-14 アボット ダイアベティス ケア インコーポレイテッドＡｂｂｏｔｔ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｉｎｃ． 医療用装置
EP2473099A4 (en) 2009-08-31 2015-01-14 Abbott Diabetes Care Inc ANALYTICAL SUBSTANCE MONITORING SYSTEM AND METHODS OF MANAGING ENERGY AND NOISE
US8571618B1 (en) * 2009-09-28 2013-10-29 Cercacor Laboratories, Inc. Adaptive calibration system for spectrophotometric measurements
WO2011041469A1 (en) 2009-09-29 2011-04-07 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
US8185181B2 (en) 2009-10-30 2012-05-22 Abbott Diabetes Care Inc. Method and apparatus for detecting false hypoglycemic conditions
EP3106871B1 (en) 2009-11-30 2021-10-27 Intuity Medical, Inc. A method of verifying the accuracy of the operation of an analyte monitoring device
WO2011094573A1 (en) 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
JP5904500B2 (ja) 2010-03-24 2016-04-13 アボット ダイアベティス ケア インコーポレイテッドＡｂｂｏｔｔ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｉｎｃ． 鋭利部材を皮膚の表面下に挿入する装置およびシステム
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
WO2011163347A2 (en) 2010-06-23 2011-12-29 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
US8635046B2 (en) 2010-06-23 2014-01-21 Abbott Diabetes Care Inc. Method and system for evaluating analyte sensor response characteristics
WO2011163519A2 (en) 2010-06-25 2011-12-29 Dexcom, Inc. Systems and methods for communicating sensor data between communication devices
EP2584964B1 (en) 2010-06-25 2021-08-04 Intuity Medical, Inc. Analyte monitoring devices
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US10092229B2 (en) 2010-06-29 2018-10-09 Abbott Diabetes Care Inc. Calibration of analyte measurement system
WO2012009613A1 (en) 2010-07-16 2012-01-19 Seventh Sense Biosystems, Inc. Low-pressure environment for fluid transfer devices
WO2012021801A2 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
US8463953B2 (en) 2010-08-18 2013-06-11 Snap-On Incorporated System and method for integrating devices for servicing a device-under-service
US8560168B2 (en) 2010-08-18 2013-10-15 Snap-On Incorporated System and method for extending communication range and reducing power consumption of vehicle diagnostic equipment
US9633492B2 (en) 2010-08-18 2017-04-25 Snap-On Incorporated System and method for a vehicle scanner to automatically execute a test suite from a storage card
US8983785B2 (en) 2010-08-18 2015-03-17 Snap-On Incorporated System and method for simultaneous display of waveforms generated from input signals received at a data acquisition device
US9117321B2 (en) * 2010-08-18 2015-08-25 Snap-On Incorporated Method and apparatus to use remote and local control modes to acquire and visually present data
US11213226B2 (en) 2010-10-07 2022-01-04 Abbott Diabetes Care Inc. Analyte monitoring devices and methods
US9241631B2 (en) 2010-10-27 2016-01-26 Dexcom, Inc. Continuous analyte monitor data recording device operable in a blinded mode
US9538943B1 (en) * 2010-10-29 2017-01-10 William Howard Cross Blood glucose monitor and method of use thereof
WO2012064802A1 (en) 2010-11-09 2012-05-18 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
US20120226117A1 (en) * 2010-12-01 2012-09-06 Lamego Marcelo M Handheld processing device including medical applications for minimally and non invasive glucose measurements
US8532775B2 (en) 2011-02-18 2013-09-10 Medtronic, Inc. Modular medical device programmer
CN103370099B (zh) 2011-02-18 2016-01-13 美敦力公司 具有可调节支架的医疗装置编程器
EP2680754B1 (en) 2011-02-28 2019-04-24 Abbott Diabetes Care, Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
JP5837570B2 (ja) * 2011-03-25 2015-12-24 テルモ株式会社 体液成分測定システム
DK3575796T3 (da) 2011-04-15 2021-01-18 Dexcom Inc Avanceret analytsensorkalibrering og fejldetektion
WO2012149155A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
EP2701600B1 (en) 2011-04-29 2016-06-08 Seventh Sense Biosystems, Inc. Delivering and/or receiving fluids
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
US9782114B2 (en) 2011-08-03 2017-10-10 Intuity Medical, Inc. Devices and methods for body fluid sampling and analysis
WO2013022775A1 (en) 2011-08-05 2013-02-14 Dexcom, Inc. Systems and methods for detecting glucose level data patterns
AU2012299169B2 (en) 2011-08-19 2017-08-24 Icu Medical, Inc. Systems and methods for a graphical interface including a graphical representation of medical data
ES2959510T3 (es) 2011-10-21 2024-02-26 Icu Medical Inc Sistema de actualización de dispositivos médicos
US9622691B2 (en) 2011-10-31 2017-04-18 Abbott Diabetes Care Inc. Model based variable risk false glucose threshold alarm prevention mechanism
US9069536B2 (en) 2011-10-31 2015-06-30 Abbott Diabetes Care Inc. Electronic devices having integrated reset systems and methods thereof
WO2013070794A2 (en) 2011-11-07 2013-05-16 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US8710993B2 (en) 2011-11-23 2014-04-29 Abbott Diabetes Care Inc. Mitigating single point failure of devices in an analyte monitoring system and methods thereof
US9317656B2 (en) 2011-11-23 2016-04-19 Abbott Diabetes Care Inc. Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof
WO2013078426A2 (en) 2011-11-25 2013-05-30 Abbott Diabetes Care Inc. Analyte monitoring system and methods of use
US9402570B2 (en) 2011-12-11 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor devices, connections, and methods
WO2013090709A1 (en) 2011-12-16 2013-06-20 Hospira, Inc. System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy
US9445759B1 (en) * 2011-12-22 2016-09-20 Cercacor Laboratories, Inc. Blood glucose calibration system
WO2013149186A1 (en) 2012-03-30 2013-10-03 Insulet Corporation Fluid delivery device with transcutaneous access tool, insertion mechansim and blood glucose monitoring for use therewith
ES2741725T3 (es) 2012-03-30 2020-02-12 Icu Medical Inc Sistema de detección de aire y método para detectar aire en una bomba de un sistema de infusión
US11798685B2 (en) * 2012-05-15 2023-10-24 James M. Minor Diagnostic methods and devices for controlling acute glycemia
EP2879733B1 (en) 2012-07-31 2019-06-05 ICU Medical, Inc. Patient care system for critical medications
EP2890297B1 (en) 2012-08-30 2018-04-11 Abbott Diabetes Care, Inc. Dropout detection in continuous analyte monitoring data during data excursions
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
EP2901153A4 (en) 2012-09-26 2016-04-27 Abbott Diabetes Care Inc METHOD AND DEVICE FOR IMPROVING DELAY CORRECTION FUNCTION DURING IN VIVO MEASUREMENT OF ANALYZ CONCENTRATION WITH ANALYZ CONCENTRATION VARIABILITY AND RANGE DATA
US9344777B2 (en) 2012-12-20 2016-05-17 Abbott Diabetes Care Inc. Wireless communication authentication for medical monitoring device
WO2014138446A1 (en) 2013-03-06 2014-09-12 Hospira,Inc. Medical device communication method
US10433773B1 (en) 2013-03-15 2019-10-08 Abbott Diabetes Care Inc. Noise rejection methods and apparatus for sparsely sampled analyte sensor data
US10076285B2 (en) 2013-03-15 2018-09-18 Abbott Diabetes Care Inc. Sensor fault detection using analyte sensor data pattern comparison
US9474475B1 (en) 2013-03-15 2016-10-25 Abbott Diabetes Care Inc. Multi-rate analyte sensor data collection with sample rate configurable signal processing
AU2014268355B2 (en) 2013-05-24 2018-06-14 Icu Medical, Inc. Multi-sensor infusion system for detecting air or an occlusion in the infusion system
ES2845748T3 (es) 2013-05-29 2021-07-27 Icu Medical Inc Sistema de infusión y método de uso que impiden la sobresaturación de un convertidor analógico-digital
ES2838450T3 (es) 2013-05-29 2021-07-02 Icu Medical Inc Sistema de infusión que utiliza uno o más sensores e información adicional para hacer una determinación de aire en relación con el sistema de infusión
WO2014205412A1 (en) 2013-06-21 2014-12-24 Intuity Medical, Inc. Analyte monitoring system with audible feedback
CA2922425C (en) 2013-08-30 2023-05-16 Hospira, Inc. System and method of monitoring and managing a remote infusion regimen
US9662436B2 (en) 2013-09-20 2017-05-30 Icu Medical, Inc. Fail-safe drug infusion therapy system
US10311972B2 (en) 2013-11-11 2019-06-04 Icu Medical, Inc. Medical device system performance index
AU2014353130B9 (en) 2013-11-19 2019-09-05 Icu Medical, Inc. Infusion pump automation system and method
US9603561B2 (en) 2013-12-16 2017-03-28 Medtronic Minimed, Inc. Methods and systems for improving the reliability of orthogonally redundant sensors
US11229382B2 (en) 2013-12-31 2022-01-25 Abbott Diabetes Care Inc. Self-powered analyte sensor and devices using the same
GB2523989B (en) 2014-01-30 2020-07-29 Insulet Netherlands B V Therapeutic product delivery system and method of pairing
CA2939302C (en) 2014-02-28 2021-12-28 Hospira, Inc. Infusion system and method which utilizes dual wavelength optical air-in-line detection
EP3865063A1 (en) 2014-03-30 2021-08-18 Abbott Diabetes Care, Inc. Method and apparatus for determining meal start and peak events in analyte monitoring systems
EP3138032A4 (en) 2014-04-30 2017-12-20 ICU Medical, Inc. Patient care system with conditional alarm forwarding
AU2015266706B2 (en) 2014-05-29 2020-01-30 Icu Medical, Inc. Infusion system and pump with configurable closed loop delivery rate catch-up
US9724470B2 (en) 2014-06-16 2017-08-08 Icu Medical, Inc. System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy
US9539383B2 (en) 2014-09-15 2017-01-10 Hospira, Inc. System and method that matches delayed infusion auto-programs with manually entered infusion programs and analyzes differences therein
USD742524S1 (en) 2014-11-17 2015-11-03 Bayer Healthcare Llc Analyte meter
US11344668B2 (en) 2014-12-19 2022-05-31 Icu Medical, Inc. Infusion system with concurrent TPN/insulin infusion
WO2016134137A1 (en) 2015-02-18 2016-08-25 Insulet Corporation Fluid delivery and infusion devices, and methods of use thereof
US10850024B2 (en) 2015-03-02 2020-12-01 Icu Medical, Inc. Infusion system, device, and method having advanced infusion features
TWD176176S (zh) * 2015-03-20 2016-06-01 五鼎生物技術股份有限公司 測量儀之部分
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
US10674944B2 (en) 2015-05-14 2020-06-09 Abbott Diabetes Care Inc. Compact medical device inserters and related systems and methods
WO2016189417A1 (en) 2015-05-26 2016-12-01 Hospira, Inc. Infusion pump system and method with multiple drug library editor source capability
CN113349766A (zh) 2015-07-10 2021-09-07 雅培糖尿病护理公司 对于生理参数进行动态葡萄糖曲线响应的系统、装置和方法
WO2017091624A1 (en) 2015-11-24 2017-06-01 Insulet Corporation Wearable automated medication delivery system
WO2017091584A1 (en) 2015-11-25 2017-06-01 Insulet Corporation Wearable medication delivery device
US10275573B2 (en) 2016-01-13 2019-04-30 Bigfoot Biomedical, Inc. User interface for diabetes management system
CN112933333B (zh) 2016-01-14 2023-03-28 比格福特生物医药公司 调整胰岛素输送速率
EP4085944A1 (en) 2016-05-13 2022-11-09 ICU Medical, Inc. Infusion pump system with common line auto flush
AU2017277804B2 (en) 2016-06-10 2022-05-26 Icu Medical, Inc. Acoustic flow sensor for continuous medication flow measurements and feedback control of infusion
US11574737B2 (en) 2016-07-14 2023-02-07 Icu Medical, Inc. Multi-communication path selection and security system for a medical device
WO2018058041A1 (en) 2016-09-23 2018-03-29 Insulet Corporation Fluid delivery device with sensor
US11071478B2 (en) 2017-01-23 2021-07-27 Abbott Diabetes Care Inc. Systems, devices and methods for analyte sensor insertion
US11045603B2 (en) 2017-02-22 2021-06-29 Insulet Corporation Needle insertion mechanisms for drug containers
EP3600014A4 (en) 2017-03-21 2020-10-21 Abbott Diabetes Care Inc. METHODS, DEVICES AND SYSTEM FOR PROVIDING DIAGNOSIS AND THERAPY FOR DIABETIC CONDITION
US10898656B2 (en) 2017-09-26 2021-01-26 Insulet Corporation Needle mechanism module for drug delivery device
AU2018354120A1 (en) 2017-10-24 2020-04-23 Dexcom, Inc. Pre-connected analyte sensors
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US11147931B2 (en) 2017-11-17 2021-10-19 Insulet Corporation Drug delivery device with air and backflow elimination
US10089055B1 (en) 2017-12-27 2018-10-02 Icu Medical, Inc. Synchronized display of screen content on networked devices
USD928199S1 (en) 2018-04-02 2021-08-17 Bigfoot Biomedical, Inc. Medication delivery device with icons
AU2019263490A1 (en) 2018-05-04 2020-11-26 Insulet Corporation Safety constraints for a control algorithm-based drug delivery system
US11152109B2 (en) 2018-07-17 2021-10-19 Icu Medical, Inc. Detecting missing messages from clinical environment
EP3824386B1 (en) 2018-07-17 2024-02-21 ICU Medical, Inc. Updating infusion pump drug libraries and operational software in a networked environment
US10861592B2 (en) 2018-07-17 2020-12-08 Icu Medical, Inc. Reducing infusion pump network congestion by staggering updates
NZ793485A (en) 2018-07-17 2023-06-30 Icu Medical Inc Systems and methods for facilitating clinical messaging in a network environment
AU2019309766A1 (en) 2018-07-26 2021-03-18 Icu Medical, Inc. Drug library management system
US10692595B2 (en) 2018-07-26 2020-06-23 Icu Medical, Inc. Drug library dynamic version management
AU2019347755B2 (en) 2018-09-28 2023-02-02 Insulet Corporation Activity mode for artificial pancreas system
US11565039B2 (en) 2018-10-11 2023-01-31 Insulet Corporation Event detection for drug delivery system
USD1002852S1 (en) 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
US11801344B2 (en) 2019-09-13 2023-10-31 Insulet Corporation Blood glucose rate of change modulation of meal and correction insulin bolus quantity
US11935637B2 (en) 2019-09-27 2024-03-19 Insulet Corporation Onboarding and total daily insulin adaptivity
US11278671B2 (en) 2019-12-04 2022-03-22 Icu Medical, Inc. Infusion pump with safety sequence keypad
WO2021113647A1 (en) 2019-12-06 2021-06-10 Insulet Corporation Techniques and devices providing adaptivity and personalization in diabetes treatment
US11833329B2 (en) 2019-12-20 2023-12-05 Insulet Corporation Techniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns
US11551802B2 (en) 2020-02-11 2023-01-10 Insulet Corporation Early meal detection and calorie intake detection
US11547800B2 (en) 2020-02-12 2023-01-10 Insulet Corporation User parameter dependent cost function for personalized reduction of hypoglycemia and/or hyperglycemia in a closed loop artificial pancreas system
US11324889B2 (en) 2020-02-14 2022-05-10 Insulet Corporation Compensation for missing readings from a glucose monitor in an automated insulin delivery system
US11766221B1 (en) * 2020-03-25 2023-09-26 Tula Health, Inc. Devices, systems, and methods for measurement validation for chronic health condition management
US11607493B2 (en) 2020-04-06 2023-03-21 Insulet Corporation Initial total daily insulin setting for user onboarding
WO2022020184A1 (en) 2020-07-21 2022-01-27 Icu Medical, Inc. Fluid transfer devices and methods of use
US11684716B2 (en) 2020-07-31 2023-06-27 Insulet Corporation Techniques to reduce risk of occlusions in drug delivery systems
USD952860S1 (en) * 2020-10-20 2022-05-24 eTouch Medical Inc. Blood glucose meter
US11135360B1 (en) 2020-12-07 2021-10-05 Icu Medical, Inc. Concurrent infusion with common line auto flush
USD999913S1 (en) 2020-12-21 2023-09-26 Abbott Diabetes Care Inc Analyte sensor inserter
US11904140B2 (en) 2021-03-10 2024-02-20 Insulet Corporation Adaptable asymmetric medicament cost component in a control system for medicament delivery
WO2023049900A1 (en) 2021-09-27 2023-03-30 Insulet Corporation Techniques enabling adaptation of parameters in aid systems by user input
US11439754B1 (en) 2021-12-01 2022-09-13 Insulet Corporation Optimizing embedded formulations for drug delivery

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140963A (en) * 1972-01-03 1979-02-20 Siemens Aktiengesellschaft Device for measuring sugar concentration
GB2054861B (en) * 1979-07-09 1983-04-07 Del Mar Avionics Portable data aquisition and storage system for monitoring patient
IT1131177B (it) * 1980-05-14 1986-06-18 Consiglio Nazionale Ricerche Comparator a banda programmabile,multicanale,per unita' cardiochirurgiche
DE3108767C2 (de) * 1981-03-07 1982-11-25 GMS, Gesellschaft für medizinische Sondentechnik mbH, 2300 Kiel Medizinischer Blutdruckaufnehmer
DE3318746C2 (de) * 1983-05-24 1985-08-14 Vladimir Dr.-Ing. 5100 Aachen Blazek Einrichtung zur Erfassung und Analyse des Durchblutungszustandes der menschlichen Haut
JPH0737946B2 (ja) * 1983-08-05 1995-04-26 株式会社京都第一科学 体液成分を測定するとともにその検査データを保存管理する装置
DD230730A3 (de) * 1984-01-02 1985-12-11 Zentralinstitut Fuer Diabetes Einrichtung zur prospektiven automatischen bestimmung individualspezifischer glukoseregulationsparameter
US4627445A (en) * 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
US4935875A (en) * 1987-12-02 1990-06-19 Data Chem, Inc. Chemical analyzer
US4890621A (en) * 1988-01-19 1990-01-02 Northstar Research Institute, Ltd. Continuous glucose monitoring and a system utilized therefor
DE3810008C1 (zh) * 1988-03-24 1989-10-26 Johannes Dr. 8000 Muenchen De Buschmann
US5204532A (en) * 1989-01-19 1993-04-20 Futrex, Inc. Method for providing general calibration for near infrared instruments for measurement of blood glucose
WO1990013872A1 (en) * 1989-04-28 1990-11-15 Pa Consulting Services Limited Computer connectors
US5190041A (en) * 1989-08-11 1993-03-02 Palti Yoram Prof System for monitoring and controlling blood glucose
US5140985A (en) * 1989-12-11 1992-08-25 Schroeder Jon M Noninvasive blood glucose measuring device
NZ238717A (en) * 1990-06-27 1994-08-26 Futrex Inc Blood glucose level measured by transmitting near-infrared energy through body part
DE4026426C2 (de) * 1990-08-21 1999-02-11 Siemens Ag System zur Datenübertragung
DE4041905A1 (de) * 1990-12-27 1992-07-02 Boehringer Mannheim Gmbh Testtraeger-analysesystem
DE4138702A1 (de) * 1991-03-22 1992-09-24 Madaus Medizin Elektronik Verfahren und vorrichtung zur diagnose und quantitativen analyse von apnoe und zur gleichzeitigen feststellung anderer erkrankungen
DE4114448C2 (de) * 1991-05-03 1995-04-20 Klaus Latschbacher Vorrichtung zur drahtlosen Datenübertragung zwischen zwei Datengeräten
DE4130369A1 (de) * 1991-09-12 1993-03-25 Siemens Ag Vorrichtung zur medizinischen bildgebung mit licht
JPH05288756A (ja) * 1992-04-13 1993-11-02 Hitachi Ltd 自動分析装置及び自動分析システム
DE4212498A1 (de) * 1992-04-14 1993-10-21 Vladimir Dr Blazek Einrichtung zur nichtinvasiven Erfassung der Blutvolumenänderung
DE4214263A1 (de) * 1992-05-03 1993-11-04 Maximilian Dr Moser Bekleidungsteil zur bedeckung menschlicher oder tierischer koerperpartien
DE4221848C2 (de) * 1992-07-03 2001-04-12 Eckhard Salzsieder Verfahren und Anordnung zur selbsttätigen in situ Kalibrierung von intrakorporalen Glukosemeßeinrichtungen
DE4300499A1 (de) * 1993-01-07 1994-07-14 Klein Karl Dittmar Dr Analytisches Verfahren für Elektrodensensoren
US5400794A (en) * 1993-03-19 1995-03-28 Gorman; Peter G. Biomedical response monitor and technique using error correction
US5417222A (en) * 1994-01-21 1995-05-23 Hewlett-Packard Company Patient monitoring system

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100407988C (zh) * 2001-01-02 2008-08-06 艾伯特糖尿病护理公司 分析物监测装置和该装置的使用方法
CN101368922B (zh) * 2003-04-10 2010-12-15 宇系科技有限公司 判断血糖浓度的方法
CN102323309A (zh) * 2004-05-30 2012-01-18 埃葛梅崔克斯股份有限公司 测量设备和与之使用的方法
CN102323309B (zh) * 2004-05-30 2014-12-17 埃葛梅崔克斯股份有限公司 测量设备和与之使用的方法
CN101233411A (zh) * 2005-07-29 2008-07-30 皇家飞利浦电子股份有限公司 在心脏疾病的诊断、管理和治疗期间对心脏利钠肽的监视
CN103251414A (zh) * 2007-06-21 2013-08-21 雅培糖尿病护理公司 用于分析物水平的检测的设备
CN103251414B (zh) * 2007-06-21 2017-05-24 雅培糖尿病护理公司 用于分析物水平的检测的设备
CN102307518A (zh) * 2009-02-03 2012-01-04 雅培糖尿病护理公司 分析物传感器和用于传感器插入的设备
CN102307518B (zh) * 2009-02-03 2015-11-25 雅培糖尿病护理公司 分析物传感器和用于传感器插入的设备

Also Published As

Publication number Publication date
ATE242997T1 (de) 2003-07-15
IL113569A (en) 1998-01-04
AU1763495A (en) 1995-12-07
TW366278B (en) 1999-08-11
DE59510722D1 (de) 2003-07-24
AU674474B2 (en) 1996-12-19
FI952131A0 (fi) 1995-05-04
KR0163476B1 (ko) 1998-12-15
CA2148569A1 (en) 1995-11-06
IL113569A0 (en) 1995-08-31
EP0680727A1 (de) 1995-11-08
HUT75243A (en) 1997-05-28
NZ272000A (en) 1997-04-24
JPH07311196A (ja) 1995-11-28
NO951754D0 (no) 1995-05-04
FI952131A (fi) 1995-11-06
HU9501274D0 (en) 1995-06-28
DE4415896A1 (de) 1995-11-09
CA2148569C (en) 2002-07-16
NO951754L (no) 1995-11-06
ZA953585B (en) 1996-11-04
US5507288A (en) 1996-04-16
EP0680727B1 (de) 2003-06-18
US5507288B1 (en) 1997-07-08
ES2201083T3 (es) 2004-03-16
DK0680727T3 (da) 2003-10-13
KR950030989A (ko) 1995-12-18
JP3568624B2 (ja) 2004-09-22

Similar Documents

Publication Publication Date Title
CN1128353A (zh) 用于监测患者血液中待分析物质的分析系统
US7947222B2 (en) Mobile communication terminal equipped with temperature compensation function for use in bio-information measurement
US10226208B2 (en) Analyte detection devices and methods with hematocrit/volume correction and feedback control
US5576544A (en) Method for providing general calibration for near infrared instruments for measurement of blood glucose
US7343185B2 (en) Measurement of body compounds
CA2045599C (en) Non-invasive measurement of blood glucose
US5068536A (en) Method for providing custom calibration for near infrared instruments for measurement of blood glucose
CA2387728C (en) Test element analysis system with an infrared detector
US20080102441A1 (en) Analyte Sensors and Methods
AU5826694A (en) Low cost means for increasing measurement sensitivity in led/ired near-infrared instruments
Park et al. Design of a portable urine glucose monitoring system for health care
US5574283A (en) Non-invasive near-infrared quantitative measurement instrument
US20210254125A1 (en) Method and device for estimating number of cells
KR20190052240A (ko) 무채혈식 휴대형 광학적 혈당 측정기 및 측정 스트립
Baig et al. Comparision between bed side testing of blood glucose by glucometer vs centralized testing in a tertiary care hospital
Lehmann et al. Clinical and technical evaluation of a new self-monitoring blood glucose meter: assessment of analytical and user error
EP1889568A1 (en) Mobile communication terminal equipped with temperature compensation function for use in bioinformation measurement
Tanaka et al. Feasibility study of a urine glucose level monitor for home healthcare using near infrared spectroscopy
Abiodun et al. Clinical Usefulness of an Enzyme Strip for Estimation of Blood Sugar (‘Dextrostix’) in a Tropical Medical Practice: A 10-year Experience
KR100680271B1 (ko) 온도 보정기능을 갖는 생체정보측정용 무선통신단말기
KR20090027322A (ko) 온도측정수단이 구비된 검체획득장치 및 이를 포함하는분석시스템
JP2004245730A (ja) 尿糖検査装置

Legal Events

Date Code Title Description
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C06 Publication
PB01 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication