CN1170564A - Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology - Google Patents
Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology Download PDFInfo
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- CN1170564A CN1170564A CN 96121462 CN96121462A CN1170564A CN 1170564 A CN1170564 A CN 1170564A CN 96121462 CN96121462 CN 96121462 CN 96121462 A CN96121462 A CN 96121462A CN 1170564 A CN1170564 A CN 1170564A
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- zinc
- nonwoven fabric
- calcium alginate
- calcium
- fiber nonwoven
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Abstract
The present invention relates to medical wound dressing. Zinc calcium alginate fibre nonwoven fabric is constituted by sodium alginate, zinc chloride and calcium chloride. The said active wound dressing has the structure of permeable adhesive tape with staple rayon and zinc calcium alginate fibre nonwoven fabric on it, and it is superior to available similar product in that it has anti-infection, inflammation diminishing and wound cure promoting effect other than the astringency effect the same as available product.
Description
The present invention relates to medical its processing technology of new product absorption styptic infection antiinflammatory medical wound dressing.
Background technology of the present invention, Britain Weir BRIT, CAIR company was in 86 years development operation Calcium Alginate fabric nonwoven cloth Wound dressings and throw in city's field boundary, this product is English by name: calcium.alginate wound, dressing, commodity are called KALTOSAT, and oneself has product of the same race on the domestic city field boundary: sea God's absorbable hemostasia series of products.This product is developed by Textile Research Inst., Ministry of Textile Industry, and its hemostatic mechanism mainly is to pass through the sodium calcium ion-exchanged by the alginic acid calcium salt when contacting with body fluid or blood, discharge calcium ion, thereby the accelerate blood process of setting is brought into play rapid anastalsis.Do not have the infection antiinflammation owing to the said goods only has anastalsis, stick and be subjected to certain limitation and numerous medical workers are accepted so be used for wound clinically.
Purpose of design of the present invention: the weak point of avoiding background technology to exist, in the Calcium Alginate molecule, introduce zinc again, make into zinc-calcium alginate double salt because the existence of zinc, after zinc-calcium alginate fiber nonwoven fabric sticks wound, by exchanging, not only when discharging calcium ion, also discharge zinc ion with sodium ion.Zinc ion is except that having the prevention infection effect, can also keep epithelial normal physiological function, control epithelial hyperkeratosis, keep the normal reparation of epithelial tissue, fibroblastic hypertrophy, epithelium formation, collagen are synthesized the very important effect of all playing.Zinc can also promote the healing of leg ulcer and other damage.Be applicable to oral ulcer, the healing of post-surgical trauma.So zinc-calcium alginate fiber nonwoven fabric of the present invention not only has anastalsis but also the infection antiinflammatory is arranged and promote the wound healing effect.
Design of the present invention: with the Sodium Alginate is raw material, material viscosity requires below 70cps (as 68,66,60cps), it is made into viscosity is the 1200--1500cps spinning liquid, this spinning liquid filters by three road flannelettes, (aperture is 0.06～0.1mm) directly to clamp-on in the mix homogeneously aqueous solution that consists of 5%～12% zinc chloride and 5%～12% calcium chloride (this aqueous solution claims solidification liquid) and make and be shaped to the zinc-calcium alginate wet fiber to filtrate by spinning head by dosing pump, the flush away solidification liquid, drawing-off, alcohol are handled, oven dry.Dried fiber is cut into the short fiber of 5cm, by combing, cross lapping, acupuncture is bonded into certain thickness bulk zinc-calcium alginate fiber nonwoven fabric, is cut into certain specification according to clinical application, sealing, packing, with behind the γShe Xianmiejun for clinical use, thereby reach purpose of the present invention.
The present invention compares with background technology, and the one, except absorbable hemostasia effect, also have the infection antiinflammatory, promote the wound healing effect with like product; The 2nd, filled up that existing like product has anastalsis and the shortcoming of not having the infection antiinflammation product more can be met clinical needs, and processing technology is simple, cost is low.
Embodiment 1: take by weighing 22.5kg, viscosity is the Sodium Alginate of 70cps, gradation adds in the pure water of a certain amount of (about 400kg), make its abundant swelling, add water to 500kg, stir evenly, through filter press three road filter pressings, directly enter in the solidification liquid of forming by 10% zinc chloride and 10% calcium chloride by the logical spinning head that is pressed through the 0.08mm aperture of dosing pump, solidifying the molten degree of depth is 35cm, batch wet fiber, the flush away solidification liquid, carry out drawing-off, draw ratio is 1: 1.2, reuse 95% Ethanol Treatment, the centrifugal ethanol of removing, oven dry, dried fiber cuts into the short fiber of 5cm, through the carding machine combing, cross lapping machine is paved into desired thickness, the more perverse bulk zinc-calcium alginate fiber nonwoven fabric that is bonded into of the hand-manipulating of needle, be cut into certain specification according to clinical application, sealing, γShe Xianmiejun is used in the packing back, and promptly making can be for the zinc-calcium alginate fiber nonwoven fabric of clinical use.
Embodiment 2: take by weighing 22.5kg, viscosity is the Sodium Alginate of 66cps, gradation adds in the pure water of a certain amount of (about 400kg), make its abundant swelling, add water to 500kg, stir evenly, through filter press three road filter pressings, directly enter in the solidification liquid of forming by 5% zinc chloride and 5% calcium chloride by the logical spinning head that is pressed through the 0.06mm aperture of dosing pump, solidifying the molten degree of depth is 38cm, batch wet fiber, the flush away solidification liquid, carry out drawing-off, draw ratio is 1: 1.3, reuse 95% Ethanol Treatment, the centrifugal ethanol of removing, oven dry, dried fiber cuts into the short fiber of 5cm, through the carding machine combing, cross lapping machine is paved into desired thickness, and hand-manipulating of needle thorn is bonded into the bulk zinc-calcium alginate fiber nonwoven fabric again, be cut into certain specification according to clinical application, sealing, γShe Xianmiejun is used in the packing back, and promptly making can be for the zinc-calcium alginate fiber nonwoven fabric of clinical use.
Embodiment 3: take by weighing 22.5kg, viscosity is the Sodium Alginate of 60cps, gradation adds in the pure water of a certain amount of (about 400kg), make its abundant swelling, add water to 500kg, stir evenly, through filter press three road filter pressings, directly enter in the solidification liquid of forming by 12% zinc chloride and 12% calcium chloride by the logical spinning head that is pressed through the 0.1mm aperture of dosing pump, solidifying the molten degree of depth is 40cm, batch wet fiber, the flush away solidification liquid carries out drawing-off, draw ratio is 1: 1.5, reuse 95% Ethanol Treatment, the centrifugal ethanol of removing, oven dry, dried fiber cuts into the short fiber of 5cm, and through the carding machine combing, cross lapping machine is paved into desired thickness, hand-manipulating of needle thorn is bonded into the bulk zinc-calcium alginate fiber nonwoven fabric again, is cut into certain specification according to clinical application, sealing, packing back is with the gamma-rays mattress that goes out.Promptly making can be for the zinc-calcium alginate fiber nonwoven fabric of clinical use.
Claims (5)
1, a kind of active wound dressing: it is characterized in that: be equipped with synthetic cotton on the breathability adhesive plaster, be equipped with zinc-calcium alginate fiber nonwoven fabric on the synthetic cotton.
2, a kind of zinc-calcium alginate fiber nonwoven fabric is characterized in that: be made of Sodium Alginate, zinc chloride, calcium chloride.
3, the processing technology of zinc-calcium alginate fiber nonwoven fabric according to claim 2, it is characterized in that: with algae extract Sodium Alginate is raw material, with the pure water is solvent, being made into viscosity is the thickness spinning liquid of 1200～1500cps, this spinning liquid filters by three road flannelettes, filtrate is extruded by dosing pump, and the spinning liquid of extruding is that the spinneret of 0.06～0.1mm directly enters the solidification liquid that contains zinc calcium by the aperture, and the coagulating bath degree of depth is 35～40cm, through the spun zinc-calcium alginate wet fiber of wet spinning, the flush away solidification liquid carries out drawing-off, and draw ratio is 1: 1.2～1.5, fine pure after the drawing-off with 95% Ethanol Treatment, the centrifugal ethanol that discards, oven dry gets bright and clean softish zinc-calcium alginate fiber, above-mentioned dried fibres is cut into the short fiber of five centimeter length, through combing, cross lapping, acupuncture is bonded into certain thickness big shape non-woven fabrics, be cut into certain specification then, sealing, packing is with supplying clinical practice behind the γShe Xianmiejun
4, according to the processing technology of the described zinc-calcium alginate fiber nonwoven fabric of claim 3, it is characterized in that: solidification liquid is the mix homogeneously aqueous solution that contains each 5%～12% concentration of calcium chloride.
5, according to claim 3 or 4 described zinc-calcium alginate fiber nonwoven fabric and processing technology, it is characterized in that; The viscosity of Sodium Alginate is below 70cps
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96121462 CN1080784C (en) | 1996-12-29 | 1996-12-29 | Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96121462 CN1080784C (en) | 1996-12-29 | 1996-12-29 | Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1170564A true CN1170564A (en) | 1998-01-21 |
| CN1080784C CN1080784C (en) | 2002-03-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96121462 Expired - Fee Related CN1080784C (en) | 1996-12-29 | 1996-12-29 | Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1080784C (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100457990C (en) * | 2007-04-16 | 2009-02-04 | 青岛大学 | Producing method and use for common and functional calcium alginate fiber |
| US7799965B2 (en) | 2006-04-11 | 2010-09-21 | Tyco Healthcare Group Lp | Wound dressings with anti-microbial and zinc-containing agents |
| WO2012109773A1 (en) * | 2011-02-18 | 2012-08-23 | Chu Jiamian | Method for preparation of medical calcium alginate filling strip |
| CN102704326A (en) * | 2012-05-25 | 2012-10-03 | 绍兴蓝海纤维科技有限公司 | Preparation method of alginic acid system nonwoven |
| US9480770B2 (en) | 2002-10-23 | 2016-11-01 | Covidien Lp | Methods for preparation of medical dressing containing antimicrobial agent |
| CN106139228A (en) * | 2016-07-29 | 2016-11-23 | 杭州英健生物科技有限公司 | Medical alginic acid zinc functional dressings and preparation method thereof |
| CN108853574A (en) * | 2017-05-10 | 2018-11-23 | 上海交通大学 | Magnesium alloy and kirsite silk material shuffling composite patch and application thereof |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1332081C (en) * | 2005-04-27 | 2007-08-15 | 武汉大学 | Blended fiber of sodium alginate/water soluble chitin, preparation method and application thereof |
| CN100336562C (en) * | 2005-05-13 | 2007-09-12 | 褚省吾 | Ultra strong absorption calcium alginate henatischesis dressing and its preparation method |
-
1996
- 1996-12-29 CN CN 96121462 patent/CN1080784C/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9480770B2 (en) | 2002-10-23 | 2016-11-01 | Covidien Lp | Methods for preparation of medical dressing containing antimicrobial agent |
| US7799965B2 (en) | 2006-04-11 | 2010-09-21 | Tyco Healthcare Group Lp | Wound dressings with anti-microbial and zinc-containing agents |
| CN100457990C (en) * | 2007-04-16 | 2009-02-04 | 青岛大学 | Producing method and use for common and functional calcium alginate fiber |
| WO2012109773A1 (en) * | 2011-02-18 | 2012-08-23 | Chu Jiamian | Method for preparation of medical calcium alginate filling strip |
| CN102704326A (en) * | 2012-05-25 | 2012-10-03 | 绍兴蓝海纤维科技有限公司 | Preparation method of alginic acid system nonwoven |
| CN102704326B (en) * | 2012-05-25 | 2014-07-02 | 绍兴蓝海纤维科技有限公司 | Preparation method of alginic acid system nonwoven |
| CN106139228A (en) * | 2016-07-29 | 2016-11-23 | 杭州英健生物科技有限公司 | Medical alginic acid zinc functional dressings and preparation method thereof |
| CN108853574A (en) * | 2017-05-10 | 2018-11-23 | 上海交通大学 | Magnesium alloy and kirsite silk material shuffling composite patch and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1080784C (en) | 2002-03-13 |
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Applicant after: Feng Hongcheng Applicant before: Kong Qinghe |
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