CN1280774A - 直接作用的抗真菌剂 - Google Patents
直接作用的抗真菌剂 Download PDFInfo
- Publication number
- CN1280774A CN1280774A CN00104379A CN00104379A CN1280774A CN 1280774 A CN1280774 A CN 1280774A CN 00104379 A CN00104379 A CN 00104379A CN 00104379 A CN00104379 A CN 00104379A CN 1280774 A CN1280774 A CN 1280774A
- Authority
- CN
- China
- Prior art keywords
- natamycin
- natamycin material
- composition
- microns
- perishables
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003429 antifungal agent Substances 0.000 title description 6
- 239000000463 material Substances 0.000 claims abstract description 309
- NCXMLFZGDNKEPB-FFPOYIOWSA-N natamycin Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C[C@@H](C)OC(=O)/C=C/[C@H]2O[C@@H]2C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 NCXMLFZGDNKEPB-FFPOYIOWSA-N 0.000 claims abstract description 275
- 239000004311 natamycin Substances 0.000 claims abstract description 274
- 229960003255 natamycin Drugs 0.000 claims abstract description 273
- 235000010298 natamycin Nutrition 0.000 claims abstract description 273
- 239000000203 mixture Substances 0.000 claims abstract description 58
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 41
- 238000000034 method Methods 0.000 claims abstract description 32
- 241000233866 Fungi Species 0.000 claims description 35
- 235000013305 food Nutrition 0.000 claims description 33
- 239000007788 liquid Substances 0.000 claims description 24
- 235000013339 cereals Nutrition 0.000 claims description 22
- 235000013351 cheese Nutrition 0.000 claims description 15
- 230000000843 anti-fungal effect Effects 0.000 claims description 14
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 13
- 238000002156 mixing Methods 0.000 claims description 13
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 12
- 235000010445 lecithin Nutrition 0.000 claims description 12
- 239000000787 lecithin Substances 0.000 claims description 12
- 229940067606 lecithin Drugs 0.000 claims description 12
- 239000012871 anti-fungal composition Substances 0.000 claims description 10
- GUBGYTABKSRVRQ-QKKXKWKRSA-N lactose group Chemical group OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000000227 grinding Methods 0.000 claims description 9
- 239000008101 lactose Substances 0.000 claims description 9
- 239000006194 liquid suspension Substances 0.000 claims description 9
- 239000011780 sodium chloride Substances 0.000 claims description 7
- 238000005054 agglomeration Methods 0.000 claims description 6
- 230000002776 aggregation Effects 0.000 claims description 6
- 239000000725 suspension Substances 0.000 claims description 6
- 235000013312 flour Nutrition 0.000 claims description 5
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims description 4
- 239000004927 clay Substances 0.000 claims description 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 3
- 229920002472 Starch Polymers 0.000 claims description 3
- 150000004676 glycans Chemical class 0.000 claims description 3
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 3
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 3
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 3
- 239000011859 microparticle Substances 0.000 claims description 3
- 229920001282 polysaccharide Polymers 0.000 claims description 3
- 239000005017 polysaccharide Substances 0.000 claims description 3
- 239000008107 starch Substances 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- 239000007921 spray Substances 0.000 claims description 2
- 235000021055 solid food Nutrition 0.000 claims 2
- 238000005507 spraying Methods 0.000 claims 2
- 239000006185 dispersion Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 abstract description 30
- 230000001857 anti-mycotic effect Effects 0.000 abstract description 18
- 239000002543 antimycotic Substances 0.000 abstract description 18
- 230000002538 fungal effect Effects 0.000 abstract description 3
- 239000000523 sample Substances 0.000 description 40
- 238000002360 preparation method Methods 0.000 description 33
- 239000007858 starting material Substances 0.000 description 13
- 239000001913 cellulose Substances 0.000 description 11
- 229920002678 cellulose Polymers 0.000 description 10
- 235000010980 cellulose Nutrition 0.000 description 10
- 230000000694 effects Effects 0.000 description 8
- 238000000855 fermentation Methods 0.000 description 8
- 230000004151 fermentation Effects 0.000 description 8
- 235000002639 sodium chloride Nutrition 0.000 description 7
- 229940121375 antifungal agent Drugs 0.000 description 6
- 239000003085 diluting agent Substances 0.000 description 6
- 238000010298 pulverizing process Methods 0.000 description 6
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 5
- 230000005764 inhibitory process Effects 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000003921 oil Substances 0.000 description 4
- 235000019198 oils Nutrition 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 238000005520 cutting process Methods 0.000 description 3
- 235000013365 dairy product Nutrition 0.000 description 3
- 235000013376 functional food Nutrition 0.000 description 3
- 239000008187 granular material Substances 0.000 description 3
- 239000008240 homogeneous mixture Substances 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 238000012856 packing Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 235000013580 sausages Nutrition 0.000 description 3
- 238000012216 screening Methods 0.000 description 3
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 241001655322 Streptomycetales Species 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 235000013622 meat product Nutrition 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 2
- 235000019731 tricalcium phosphate Nutrition 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 239000002028 Biomass Substances 0.000 description 1
- 240000004160 Capsicum annuum Species 0.000 description 1
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- 235000019764 Soybean Meal Nutrition 0.000 description 1
- 241000970906 Streptomyces natalensis Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- UUVBYOGFRMMMQL-UHFFFAOYSA-N calcium;phosphoric acid Chemical compound [Ca].OP(O)(O)=O UUVBYOGFRMMMQL-UHFFFAOYSA-N 0.000 description 1
- 239000000828 canola oil Substances 0.000 description 1
- 235000019519 canola oil Nutrition 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 description 1
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000008157 edible vegetable oil Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 235000012041 food component Nutrition 0.000 description 1
- 239000005417 food ingredient Substances 0.000 description 1
- 239000004459 forage Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 229910052901 montmorillonite Inorganic materials 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 229920003124 powdered cellulose Polymers 0.000 description 1
- 235000019814 powdered cellulose Nutrition 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 239000011802 pulverized particle Substances 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 230000005070 ripening Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 239000004455 soybean meal Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000012258 stirred mixture Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 235000020238 sunflower seed Nutrition 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/34635—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/097—Preservation
- A23C19/10—Addition of preservatives
- A23C19/11—Addition of preservatives of antibiotics or bacteriocins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C12P19/626—Natamycin; Pimaricin; Tennecetin
Abstract
Description
样品 | 平均直径(μm) | 中间直径(μm) |
商业样品1精细样品1商业样品2精细样品2 | 29.232.6516.432.54 | 14.832.5612.612.58 |
样品 | 平均直径(μm) | 中间直径(μm) |
商业样品1精细样品1商业2精细2 | 29.238.1516.438.24 | 14.838.0212.618.02 |
样品 | 平均直径(μm) | 比表面积(m2/g) |
商业混合物精细混合物商业混合物 | 57.25.0454.02 | 0.863.40.99 |
w/Ca3(PO4)2 | ||
精细混合物w/ | 4.78 | 3.44 |
Ca3(PO4)2 |
腐败样品袋的数目(x/10) | |||||
储存天数 | 样品1常规2.5ppm | 样品2精细2.5ppm | 样品3常规9ppm | 样品4对照无添加物 | 样品5对照加纤维素 |
46天74天106天145天179天193天223天 | 1/105/109/10全部全部全部全部 | 0/100/103/104/105/106/109/10 | 0/100/100/103/104/105/108/10 | 7/109/10全部全部全部全部全部 | 9/10全部全部全部全部全部全部 |
Claims (35)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/354,829 | 1999-07-16 | ||
US09/354,829 US6291436B1 (en) | 1999-07-16 | 1999-07-16 | Direct action anti-mycotic |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1280774A true CN1280774A (zh) | 2001-01-24 |
CN1149929C CN1149929C (zh) | 2004-05-19 |
Family
ID=23395065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB00104379XA Expired - Fee Related CN1149929C (zh) | 1999-07-16 | 2000-03-23 | 直接作用的抗真菌剂 |
Country Status (12)
Country | Link |
---|---|
US (2) | US6291436B1 (zh) |
EP (1) | EP1068809B1 (zh) |
JP (1) | JP2001039805A (zh) |
KR (1) | KR20010014444A (zh) |
CN (1) | CN1149929C (zh) |
AT (1) | ATE321465T1 (zh) |
AU (1) | AU779866B2 (zh) |
BR (1) | BR0000195A (zh) |
CA (1) | CA2291382C (zh) |
DE (1) | DE60026936T2 (zh) |
MX (1) | MXPA99011186A (zh) |
RU (1) | RU2255615C2 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8574645B2 (en) | 2004-09-23 | 2013-11-05 | Dsm Ip Assets B.V. | Antimicrobial composition |
CN104431228A (zh) * | 2014-11-19 | 2015-03-25 | 广东济公保健食品有限公司 | 抗结剂组合物、佛手果味糖及其制备方法 |
CN109310093A (zh) * | 2016-04-18 | 2019-02-05 | Arec作物保护有限公司 | 游霉素组合物及其用途 |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6291436B1 (en) * | 1999-07-16 | 2001-09-18 | International Fiber Corporation | Direct action anti-mycotic |
BR0215014A (pt) * | 2001-12-21 | 2004-11-09 | Dsm Ip Assets Bv | Método aperfeiçoado para o tratamento de produtos alimentìcios, produtos de alimentos para animais ou produtos agrìcolas com um composto de polieno antifúngico |
US20050233032A1 (en) * | 2002-02-14 | 2005-10-20 | Sa Majeste La Reine Du Chef Du Canada | Mixed starter culture and uses thereof |
BR0311253A (pt) * | 2002-06-03 | 2007-04-27 | Dsm Ip Assets Bv | método para o tratamento de queijo desfribrado com um composto antifúngico de polieno |
EP1526777A2 (en) * | 2002-08-06 | 2005-05-04 | DSM IP Assets B.V. | Method for the covering of food with polyene antifungal compositions |
MXPA06002060A (es) * | 2003-08-22 | 2006-05-19 | Danisco | Composicion que comprende una bacteriocina y un extracto a partir de una planta de la familia labiatae. |
US20070042184A1 (en) * | 2003-08-22 | 2007-02-22 | Danisco A/S | Microcapsules |
US20050226974A1 (en) * | 2004-04-08 | 2005-10-13 | John Faragher | Natamycin dosage form, process for preparing same, method for preserving a food product and preserved food product |
US20060210694A1 (en) * | 2005-03-18 | 2006-09-21 | Chappell Rulon A | Anti-caking agents and methods |
WO2007039572A1 (en) | 2005-10-04 | 2007-04-12 | Dsm Ip Assets B.V. | Improved anti-fungal composition |
NZ596594A (en) * | 2007-03-15 | 2013-08-30 | Dsm Ip Assets Bv | Stabilized micronised particles |
UA103177C2 (ru) * | 2007-10-12 | 2013-09-25 | Дсм Іп Ассетс Б.В. | Способ созревания сыра в фольге |
EA201101215A1 (ru) * | 2009-02-17 | 2012-02-28 | ДСМ АйПи АССЕТС Б.В. | Способ созревания сыра в пленке |
US9445608B2 (en) * | 2011-03-31 | 2016-09-20 | Caravan Ingredients Inc. | Antimicrobial powders for the preparation of bakery products |
US20170006890A1 (en) * | 2014-02-13 | 2017-01-12 | Dsm Ip Assets B.V. | Production of cheese |
ES2754586T3 (es) | 2015-03-19 | 2020-04-20 | Valent Biosciences Llc | Formulaciones en suspensión de natamicina concentradas |
CN108135228A (zh) * | 2015-09-09 | 2018-06-08 | Arec作物保护有限公司 | 包括纳他霉素和c4-c22脂肪酸,该脂肪酸的甘油单酯和/或该脂肪酸的衍生物的抗真菌组合物 |
CN109562318A (zh) | 2016-07-05 | 2019-04-02 | 英力士美国有限公司 | 用于回收酸性气体处理中的吸收剂的方法和设备 |
Family Cites Families (17)
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---|---|---|---|---|
US3996386A (en) * | 1971-12-15 | 1976-12-07 | Yrjo Malkki | Method for preventing microbial surface deterioration of foods and feeds |
US4536494A (en) * | 1983-11-17 | 1985-08-20 | Carter A Franklin | Animal feed method employing natamycin |
US4950477A (en) * | 1988-08-23 | 1990-08-21 | Memorial Hospital For Cancer And Allied Dieseas | Method of preventing and treating pulmonary infection by fungi using aerosolized polyenes |
ATE176155T1 (de) * | 1990-11-16 | 1999-02-15 | Nippon Shinyaku Co Ltd | Injizierbare amphotericin b enthaltende dispersion |
CA2114102C (en) * | 1991-07-25 | 2002-09-17 | Bruce Dexter King | Natamycin treatment of dried whole kernel grains |
US5231014A (en) | 1991-08-05 | 1993-07-27 | Bio-Technical Resources | Fermentation process for producing natamycin |
US5902579A (en) | 1991-08-05 | 1999-05-11 | Bio-Technical Resources | Natamycin-containing streptomyces biomass and its use in animal feed |
US5266347A (en) | 1992-01-28 | 1993-11-30 | Ducoa L.P. | Antibiotic biomass animal feed compositions |
EP0608575A1 (en) | 1993-01-27 | 1994-08-03 | Dsm N.V. | A composition which is cured by exposure to ultraviolet light in the absence of solvent |
WO1995008918A1 (en) * | 1993-09-29 | 1995-04-06 | Gist-Brocades N.V. | A novel antifungal composition |
US5626893A (en) * | 1994-10-18 | 1997-05-06 | Reddy; Malireddy S. | Method of treating a divided cheese product for anticaking |
ATE239091T1 (de) * | 1996-02-09 | 2003-05-15 | Dsm Nv | Natamycin gewinnung |
US5895680A (en) | 1996-06-19 | 1999-04-20 | Thomas J. Lipton | Foodstuff preservation |
US6132787A (en) * | 1997-04-25 | 2000-10-17 | The Procter & Gamble Company | Antimicrobial combinations of a sorbate preservative natamycin and a dialkyl dicarbonate useful in treating beverages and other food products and process of making |
US6045815A (en) * | 1997-08-15 | 2000-04-04 | Board Of Regents, The University Of Texas System | Parenteral pimaricin as treatment of systemic infections |
US6126974A (en) * | 1998-03-13 | 2000-10-03 | Protein X Technologies Int'l Inc. | Anti-caking anti-mycotic food ingredient and process for producing the same |
US6291436B1 (en) * | 1999-07-16 | 2001-09-18 | International Fiber Corporation | Direct action anti-mycotic |
-
1999
- 1999-07-16 US US09/354,829 patent/US6291436B1/en not_active Expired - Lifetime
- 1999-11-25 CA CA002291382A patent/CA2291382C/en not_active Expired - Fee Related
- 1999-12-02 MX MXPA99011186A patent/MXPA99011186A/es active IP Right Grant
-
2000
- 2000-01-18 KR KR1020000002125A patent/KR20010014444A/ko not_active Application Discontinuation
- 2000-01-27 BR BR0000195-3A patent/BR0000195A/pt not_active Application Discontinuation
- 2000-02-17 RU RU2000103675/13A patent/RU2255615C2/ru not_active IP Right Cessation
- 2000-03-23 CN CNB00104379XA patent/CN1149929C/zh not_active Expired - Fee Related
- 2000-04-28 JP JP2000128745A patent/JP2001039805A/ja active Pending
- 2000-05-31 DE DE60026936T patent/DE60026936T2/de not_active Expired - Lifetime
- 2000-05-31 EP EP00304608A patent/EP1068809B1/en not_active Expired - Lifetime
- 2000-05-31 AT AT00304608T patent/ATE321465T1/de not_active IP Right Cessation
- 2000-07-13 AU AU47217/00A patent/AU779866B2/en not_active Ceased
-
2001
- 2001-05-11 US US09/853,312 patent/US6576617B2/en not_active Expired - Lifetime
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8574645B2 (en) | 2004-09-23 | 2013-11-05 | Dsm Ip Assets B.V. | Antimicrobial composition |
CN104273636A (zh) * | 2004-09-23 | 2015-01-14 | 帝斯曼知识产权资产管理有限公司 | 抗微生物组合物 |
CN104431228A (zh) * | 2014-11-19 | 2015-03-25 | 广东济公保健食品有限公司 | 抗结剂组合物、佛手果味糖及其制备方法 |
CN104431228B (zh) * | 2014-11-19 | 2017-10-17 | 广东济公保健食品有限公司 | 抗结剂组合物、佛手果味糖及其制备方法 |
CN109310093A (zh) * | 2016-04-18 | 2019-02-05 | Arec作物保护有限公司 | 游霉素组合物及其用途 |
US11317631B2 (en) | 2016-04-18 | 2022-05-03 | Arec Crop Protection B.V. | Natamycin compositions and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
JP2001039805A (ja) | 2001-02-13 |
EP1068809A3 (en) | 2002-01-02 |
US20030087003A1 (en) | 2003-05-08 |
CA2291382C (en) | 2003-10-21 |
RU2255615C2 (ru) | 2005-07-10 |
US6576617B2 (en) | 2003-06-10 |
DE60026936D1 (de) | 2006-05-18 |
CA2291382A1 (en) | 2001-01-16 |
DE60026936T2 (de) | 2007-03-15 |
ATE321465T1 (de) | 2006-04-15 |
KR20010014444A (ko) | 2001-02-26 |
CN1149929C (zh) | 2004-05-19 |
US6291436B1 (en) | 2001-09-18 |
EP1068809A2 (en) | 2001-01-17 |
MXPA99011186A (es) | 2004-09-01 |
AU779866B2 (en) | 2005-02-17 |
EP1068809B1 (en) | 2006-03-29 |
AU4721700A (en) | 2001-01-18 |
BR0000195A (pt) | 2001-08-21 |
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