CN1308672C - 保护光学测量仪器的测试片台架 - Google Patents
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Abstract
用于使用测试片的测试仪器类型的测试片台架,其中台架具有限定测试片轨道的屏板,可将插入的片条定位于光孔上方以测定分析物。台架具有固定安装在屏板上的防护罩,它位于光学窗口上方并可保护光学测试仪器。片条轨道具有将片条保持在测试位置上的稳定件。防护罩用于引导插入的片条的前沿与稳定件相啮合,以保证片条的适当插入。
Description
技术领域
本发明总的涉及分析物的测定,具体涉及基于反射的光学监测系统,例如在一次性测试片上进行基于酶的血分析物的化学分析所用的系统(例如血糖测试系统),尤其涉及用于保护这种系统的光学装置免受污染和保证测试片适当地插入监测系统的仪器。
背景技术
包括血糖计的便携式分析物监测系统在本领域广为人知。就血糖计来说,这些监测器是典型的便携式测量仪器,可用于个人特别是糖尿病患者监测血糖的水平。自从19世纪70年代以来,在糖尿病需要注射胰岛素之时,这些设备获得了不断增长的普及和个人家庭使用的接受。由于电子学、光学和测试片化学技术的发展,这些测量仪器已经不断地变得轻便、精确和方便。
如今使用最为普及的血糖计类型是基于光的反射并结合一次性使用的测试片。在使用中,使用携带与血反应的化学试剂的小块测试片,例如美国专利号5,296,192中所述,在此将结合其内容作为参考。当新鲜的全血,特别是来自病人割开的手指,被应用在测试片上,发生的酶基反应产生了颜色变化,其典型的染色变化与呈现在血样中的葡萄糖浓度成比例。在加入血使反应进行之后,测试片于是被插入监测仪器,光反射被用于测量颜色的变化。一旦仪器确定反应充分完成(最适宜在反应稳定时发生),反射测量可通过在监测仪器中的软件转化成葡萄糖测量,典型地以毫克/分升为单位并在显示屏上报告使用者。
这种光学监测仪器依靠适当的测试片插入以保证含有血样和化学试剂的测试片部分精确地对准光学测量装置。另外,如果光学装置受到血或其它外部物质的污染,精确度也会受到损害。由于糖尿病患者使用这些监测仪器,他们会经常受到视力和运动的协调变差之累,因此重要的是监测仪器应便于适当的引入测试片和引导测试片的对准,以及保护光学装置免受污染。由于其可携带性,这些仪器会遭受各种粗糙的环境和搬运,在这些情况下光学装置均可能被污染。
现有技术的仪器不足以满足这些要求。在美国专利号5,843,692中描述了一种以ONE TOUCH为名出售的流行的测量器。此设备需要先将测试片插入测量器,然后将血加在测试片上。这种方法对使用者并不方便,当他或她必须将刺破的手指对准测试片上的测试位置时,它却正位于测量器中。因此,这导致了疏忽时血液会溢出到测量器上,并因此污染了其光学装置。在一大滴血直接沉到测试片上时,会时常发生这种情况。此装置在使用时还利用门来遮蔽光学装置周围的光线,这将在测量器不使用时保护光学装置。不幸的是,门的打开和关闭增加了测试过程的步骤。另外,由于此仪器的光学系统需要门来遮挡周围的光线,门的损坏会致使仪器无法使用。
发明内容
本领域需要一种便携式监测仪器,它可保证测试片适当对准其光学装置,以及保护光学装置免受污染。
本发明涉及一种方法和仪器,其可保证测试片适当插入并对准光反射计,并且同时保护光学测量装置。
更具体地说,本发明涉及一种测试片台架,它可用来容纳分析测定的测试片,该测试片台架包括:一屏板部分,包括:一测试片轨道,其尺寸可在其中容纳一测试片,以及在允许测试片沿测试片的纵向尺寸的方向可滑动地被插入时,向测试片提供横向的稳定性;一光孔,该光孔被定位成提供通向容纳在测试片轨道内的测试片的光学通道;至少一个稳定件,其在光孔附近伸入测试片轨道,以保持测试片相对于光孔处在一个预定的位置;一防护罩部分,其固定附连于屏板部分,以便对光孔加以保护,该防护罩部分包括:至少一个斜面构件,该斜面构件具有一斜面,以引导测试片的表面特征与至少一个稳定件相啮合。
本发明还涉及一种进行分析测定的方法,该方法包括以下步骤:提供如前面所述的测试片台架;提供一具有前沿和色斑的测试片;将含有分析物的材料施加于测试片,以使在色斑处引起可测量的光学变化;将测试片引入测试片轨道;使测试片前进,以使由至少一个斜面构件引导的测试片的表面特征与至少一个稳定件相啮合,直至色斑位于光孔上方为止;观察色斑以进行分析测定。
根据本发明的实施例的一个方面,测试片接收件或屏板具有一位于监测仪器的光学装置上方的光学窗口。屏板上设有一保护性光学罩盖或防护罩,以保护光学窗口下方的光学装置免受外来物质的污染。
根据本发明的实施例的另一方面,屏板具有一将测试片引导到测试位置的轨道。屏板设有指状物,所述指状物用于啮合测试片上的配合凹痕,以便触觉地指示测试片的适当测试位置。
根据本发明的实施例的又一方面,保护性防护罩固定安装在屏板上并具有可引导插入的测试片前沿的斜面构件,使得指状物可适当将其接收并引入适当的测试位置。
本发明的这些和其它的特征和优点将结合附图所示的本发明的实施例得到容易的理解。
附图说明
图1是本发明的具有创造性的测试片台架的便携式监测仪器的立体图,描述了传统测试片的插入。
图2示出了根据本发明的测试片台架的实施例的立体分解图。
图3是底面和防护罩的斜面构件的立体图。
图4A是现有技术的测试片的俯视图。
图4B是现有技术的测试片的仰视图。
图5是防护罩固定安装在屏板上后,图2的屏板沿线A-A和防护罩沿线A’-A’的横截面示意图。
具体实施方式
为了促进对本发明原理的理解,附图中描述的本发明的实施例的示意图将作为参考。
参见图1,描述了一便携式测试仪器2,例如用于测量全血中的血糖,由佛罗里达州Ft.Lauderdale的Home Diagnostics股份有限公司制造的商标为PRESTIGELX的类型。仪器的外罩容纳了在应用测试片200的示例中基于微处理器计算血糖浓度的电子装置。仪器2具有可以是液晶显示器的显示屏4,用于报告使用者的计算结果和其它信息。测试片200被插入测试片接收台架6,下面将会对它进行详细讨论。
图2是图1所示台架6的分解示意图。可从仪器2上拆卸的台架便于清除血迹和其它杂质,并且可以接近覆盖仪器的光学装置的窗口(图中未显示)。台架6的移动允许光学窗口被清洁以保证仪器2的最佳性能。台架6包括两个固定在一起的主要部件,它们是屏板10和防护罩100,将在下文中依次讨论。
屏板10接收测试片并将其引导到测量位置以便适当操作。屏板10具有低于屏板顶面的空腔12,横向尺寸可使测试片紧密地滑动,间隙样式保证在允许测试片前进时的横向稳定性。在空腔12的每一边上均有一稳定件或指状物14,它从与对面的指状物相反的直径方向伸入空腔。这些指状物14施压于从适当位置插入空腔12的测试片,以使光学装置更好地读数。在插入时,测试片紧密地对着空腔12的底面以使下面将要阐述的色斑被保持在光孔20上方。在台架6固定在测量仪器2上时,光孔20被定位在仪器的光学装置上方。屏板10也有固定地附连在此处的防护罩上的装置16,以及将台架6可移动地附连在测量仪器外罩上的装置18。
图2中还描述了第二主台架部件是防护罩100。防护罩100用来保护位于光孔20下方的光学测量装置,以及还帮助引导测试片进入适当的测试位置,这在下文中将讨论到。防护罩具有将其固定地附连在屏板10上的装置102。如同所述,防护罩上的装置102与固定地安装在屏板上的协作装置16紧密配合。所述的这些特征将被示出,并且会用已知工艺中的大量机械的手段和方法之一提供部件间的固定附连,例如胶合、焊接、超声波或射频焊接,或者很坚固的机械锁定或棘爪。
请参见图3,所示的是防护罩100的下侧。为了允许使用者在防护罩100被固定地附连在屏板10上时目睹插入的测试片的前沿的前进,提供了观测槽104。还提供了斜面构件106,所述斜面构件设有一向下倾斜的表面,当防护罩100被固定地附连在屏板10上时,该斜面用于推动屏板的指状物14下方的插入测试片的前沿。根据图5将深入论述此特征,它会在简要叙述图4A和4B所示的现有技术的测试片后被讨论。
参见图4A,描述了现有技术的测试片的上表面,例如美国专利号5,296,192所述。测试片200具有取样口或测试点202,在将测试片引入仪器2之前,血将施加在其上面。测试片200还具有凹痕204或其它配合指状物14的表面特征。当然,可以在台架中设置其它配合结构,以啮合位于测试片上的任何位置的类似凹痕。凹痕在测试片插入正确的测试位置(也就是,使下述的色斑定向在屏板的光孔20上方)时提供用于指示的触觉引导,以及还提供保持测试片位置的阻力。用手拉动测试片可以容易地克服阻力,但如果在测试的过程中测量器被重新定向或受到震动,它足以使测试片保持测试的位置。测试片200也可具有镶边206,测量仪器2在测试片被全部插入时将其用于光学检测。全部插入通常可表示测试的位置,以及将与诸如指状物14上的装置等配合结构与凹痕204啮合的位置相对应。镶边206同样可通过图2和3所示的观测槽104示意性地让使用者确信测试片已经被适当地插入。当测试片200的底侧上没有镶边时,使用者可以通过槽104目睹前沿是否含有所示镶边206以及测试片是否被适当地插入。
图4B描述了图4A所示测试片的底面。观察孔或色斑208基本上位于测试点204正下方。当含有分析物的流体施加在测试点202上时,它经过含有化学物质的元件在测试片中产生色彩变化,如果所加样品足量,可以在测试仪器2中插入测试片200前观察色斑208使其得到证实。在测试片插入正确的测试位置时,色斑208位于屏板中的光孔20上方以使光学测量装置接近色斑208。
现在请参见图5,该图示出了台架6的横截面示意图,显示了屏板10和防护罩100互相固定地相连。屏板10和防护罩100的横截面分别沿着剖面线A-A和A’-A’。可见,图1中对应于测试片轨道22的空腔12,其中测试片将沿箭头B的方向插入。可以理解的是,被插入的测试片的前沿将遇到斜面构件106并向下偏转致使前沿通过指状物14下方。如同所示,在图4A和4B中描述的现有技术的测试片中,突起14a提供了与凹痕204配合的结构。又如所示,光孔20位于以示意的方式描述的光学测量装置300的上方,可以理解的是,台架的防护罩部分100保护光学装置300免受污染。
当附图和前面的叙述详细地说明和叙述了本发明时,在特性上相同将被视为是说明性的和非局限性的,应当理解的是所示和所述的只是说明性的实施例,所有落在本发明的精神和范围之中的变化和修改都将得到保护。例如,本发明的应用并不局限在光的反射系数的测量或血糖水平的测量,还将发现任何需要插入测试片的测量类型的应用。
Claims (11)
1.一种测试片台架,它可用来容纳分析测定的测试片,所述测试片台架包括:
一屏板部分,包括:
一测试片轨道,其尺寸可在其中容纳一测试片,以及在允许所述测试片沿所述测试片的纵向尺寸的方向可滑动地被插入时,向所述测试片提供横向的稳定性;
一光孔,所述光孔被定位成提供通向容纳在所述测试片轨道内的测试片的光学通道;
至少一个稳定件,其在所述光孔附近伸入所述测试片轨道,以保持所述测试片相对于所述光孔处在一个预定的位置;
一防护罩部分,其固定附连于所述屏板部分,以便对所述光孔加以保护,所述防护罩部分包括:
至少一个斜面构件,所述斜面构件具有一斜面,以引导所述测试片的表面特征与所述至少一个稳定件相啮合。
2.如权利要求1所述的测试片台架,其特征在于,所述至少一个稳定件包括至少一个指状部件。
3.如权利要求2所述的测试片台架,其特征在于,所述至少一个指状部件还包括用于啮合所述测试片上的凹痕的突出部。
4.如权利要求1所述的测试片台架,其特征在于,它还包括用于啮合被插入的测试片上的凹痕的结构,以便在测试片完全插入后提供所述测试片的保持力。
5.如权利要求4所述的测试片台架,其特征在于,所述结构还提供了测试片完全插入的触觉指示。
6.如权利要求3所述的测试片台架,其特征在于,有两个指状物。
7.如权利要求1所述的测试片台架,其特征在于,有两个斜面构件。
8.一种包括如权利要求1所述的测试片台架的测试仪器。
9.一种进行分析测定的方法,该方法包括以下步骤:
提供如权利要求7所述的测试片台架;
提供一具有前沿和色斑的测试片;
将含有分析物的材料施加于所述测试片,以使在所述色斑处引起可测量的光学变化;
将测试片引入所述测试片轨道;
使所述测试片前进,以使由所述至少一个斜面构件引导的所述测试片的表面特征与所述至少一个稳定件相啮合,直至所述色斑位于所述光孔上方为止;
观察所述色斑以进行分析测定。
10.如权利要求9所述的方法,其特征在于,还包括在所述色斑位于所述光孔上方时将所述测试片保持就位在所述测试片轨道中的步骤。
11.如权利要求9所述的方法,其特征在于,还包括在所述色斑位于所述光孔上方时提供触觉指示的步骤。
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US09/448,711 | 1999-11-24 | ||
US09/448,711 US6458326B1 (en) | 1999-11-24 | 1999-11-24 | Protective test strip platform |
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CN1308672C true CN1308672C (zh) | 2007-04-04 |
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EP (1) | EP1157269B1 (zh) |
CN (1) | CN1308672C (zh) |
AT (1) | ATE288077T1 (zh) |
AU (1) | AU1662001A (zh) |
CA (1) | CA2365360A1 (zh) |
DE (1) | DE60017713T2 (zh) |
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US6036924A (en) | 1997-12-04 | 2000-03-14 | Hewlett-Packard Company | Cassette of lancet cartridges for sampling blood |
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- 2000-11-22 CN CNB008049564A patent/CN1308672C/zh not_active Expired - Lifetime
- 2000-11-22 AU AU16620/01A patent/AU1662001A/en not_active Abandoned
- 2000-11-22 WO PCT/US2000/032042 patent/WO2001038859A1/en active IP Right Grant
- 2000-11-22 EP EP00979217A patent/EP1157269B1/en not_active Expired - Lifetime
- 2000-11-22 AT AT00979217T patent/ATE288077T1/de active
- 2000-11-22 DE DE60017713T patent/DE60017713T2/de not_active Expired - Lifetime
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2002
- 2002-08-01 US US10/208,878 patent/US6979571B2/en not_active Expired - Fee Related
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Also Published As
Publication number | Publication date |
---|---|
WO2001038859A1 (en) | 2001-05-31 |
HK1045370A1 (en) | 2002-11-22 |
DE60017713D1 (de) | 2005-03-03 |
EP1157269A1 (en) | 2001-11-28 |
ATE288077T1 (de) | 2005-02-15 |
DE60017713T2 (de) | 2005-12-22 |
US6979571B2 (en) | 2005-12-27 |
US6458326B1 (en) | 2002-10-01 |
US20030026734A1 (en) | 2003-02-06 |
CN1343307A (zh) | 2002-04-03 |
HK1045370B (zh) | 2007-06-29 |
WO2001038859A9 (en) | 2002-05-16 |
EP1157269B1 (en) | 2005-01-26 |
CA2365360A1 (en) | 2001-05-31 |
AU1662001A (en) | 2001-06-04 |
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