CN1314916A - 基于癌抑制基因wt1的产物的癌抗原 - Google Patents
基于癌抑制基因wt1的产物的癌抗原 Download PDFInfo
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Abstract
Description
肽 | Kd(M) |
Db126WH187 | 1.89×10-67.61×10-6 |
小鼠A | 小鼠B | |
肽+肽- | 76.6%4.9% | 37.2%0.9% |
Claims (7)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21809398 | 1998-07-31 | ||
JP218093/1998 | 1998-07-31 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CN2011101028829A Division CN102198266A (zh) | 1998-07-31 | 1999-07-30 | 基于癌抑制基因wt1的产物的癌抗原 |
CN2004100492708A Division CN1560078B (zh) | 1998-07-31 | 1999-07-30 | 基于癌抑制基因wt1的产物的癌抗原 |
Publications (2)
Publication Number | Publication Date |
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CN1314916A true CN1314916A (zh) | 2001-09-26 |
CN1178956C CN1178956C (zh) | 2004-12-08 |
Family
ID=16714530
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Application Number | Title | Priority Date | Filing Date |
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CNB2005100995114A Expired - Lifetime CN100560130C (zh) | 1998-07-31 | 1999-07-30 | 基于癌抑制基因wt1的产物的癌抗原 |
CNB998102091A Expired - Lifetime CN1178956C (zh) | 1998-07-31 | 1999-07-30 | 基于癌抑制基因wt1的产物的癌抗原 |
CN2004100492708A Expired - Lifetime CN1560078B (zh) | 1998-07-31 | 1999-07-30 | 基于癌抑制基因wt1的产物的癌抗原 |
CN2011101028829A Pending CN102198266A (zh) | 1998-07-31 | 1999-07-30 | 基于癌抑制基因wt1的产物的癌抗原 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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CNB2005100995114A Expired - Lifetime CN100560130C (zh) | 1998-07-31 | 1999-07-30 | 基于癌抑制基因wt1的产物的癌抗原 |
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Application Number | Title | Priority Date | Filing Date |
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CN2004100492708A Expired - Lifetime CN1560078B (zh) | 1998-07-31 | 1999-07-30 | 基于癌抑制基因wt1的产物的癌抗原 |
CN2011101028829A Pending CN102198266A (zh) | 1998-07-31 | 1999-07-30 | 基于癌抑制基因wt1的产物的癌抗原 |
Country Status (15)
Country | Link |
---|---|
US (7) | US7030212B1 (zh) |
EP (3) | EP2048160B1 (zh) |
JP (2) | JP4422903B2 (zh) |
KR (1) | KR100767554B1 (zh) |
CN (4) | CN100560130C (zh) |
AT (1) | ATE420112T1 (zh) |
AU (1) | AU4932199A (zh) |
BR (1) | BRPI9912663B8 (zh) |
CA (1) | CA2337743C (zh) |
DE (1) | DE69940264D1 (zh) |
DK (1) | DK1103564T3 (zh) |
ES (1) | ES2318898T3 (zh) |
HK (4) | HK1036073A1 (zh) |
PT (1) | PT1103564E (zh) |
WO (1) | WO2000006602A1 (zh) |
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CN100486995C (zh) * | 1998-09-30 | 2009-05-13 | 科里克萨有限公司 | 用于wt1特异性免疫治疗的组合物和方法 |
CN101851275A (zh) * | 2003-01-15 | 2010-10-06 | 株式会社国际癌症免疫研究所 | 二聚体化肽 |
CN1560078B (zh) * | 1998-07-31 | 2011-06-22 | 株式会社国际癌症免疫研究所 | 基于癌抑制基因wt1的产物的癌抗原 |
CN101580538B (zh) * | 2003-11-05 | 2013-06-19 | 株式会社国际癌症免疫研究所 | Wt1衍生的hla-dr-结合抗原肽 |
CN105903006A (zh) * | 2007-12-05 | 2016-08-31 | 株式会社癌免疫研究所 | 癌症疫苗组合物 |
CN108348552A (zh) * | 2015-09-10 | 2018-07-31 | 纪念斯隆-凯特林癌症中心 | 通过t细胞疗法来治疗多发性骨髓瘤和浆细胞性白血病的方法 |
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-
1999
- 1999-07-30 BR BRPI9912663 patent/BRPI9912663B8/pt unknown
- 1999-07-30 CA CA2337743A patent/CA2337743C/en not_active Expired - Lifetime
- 1999-07-30 CN CNB2005100995114A patent/CN100560130C/zh not_active Expired - Lifetime
- 1999-07-30 AT AT99933205T patent/ATE420112T1/de active
- 1999-07-30 DK DK99933205T patent/DK1103564T3/da active
- 1999-07-30 AU AU49321/99A patent/AU4932199A/en not_active Abandoned
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1560078B (zh) * | 1998-07-31 | 2011-06-22 | 株式会社国际癌症免疫研究所 | 基于癌抑制基因wt1的产物的癌抗原 |
CN100486995C (zh) * | 1998-09-30 | 2009-05-13 | 科里克萨有限公司 | 用于wt1特异性免疫治疗的组合物和方法 |
CN101851275A (zh) * | 2003-01-15 | 2010-10-06 | 株式会社国际癌症免疫研究所 | 二聚体化肽 |
CN101580538B (zh) * | 2003-11-05 | 2013-06-19 | 株式会社国际癌症免疫研究所 | Wt1衍生的hla-dr-结合抗原肽 |
CN105903006A (zh) * | 2007-12-05 | 2016-08-31 | 株式会社癌免疫研究所 | 癌症疫苗组合物 |
CN103394079B (zh) * | 2007-12-05 | 2017-03-01 | 株式会社癌免疫研究所 | 癌症疫苗组合物 |
CN108348552A (zh) * | 2015-09-10 | 2018-07-31 | 纪念斯隆-凯特林癌症中心 | 通过t细胞疗法来治疗多发性骨髓瘤和浆细胞性白血病的方法 |
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