CN1496272A - 用于透析治疗的碳酸氢盐基溶剂 - Google Patents
用于透析治疗的碳酸氢盐基溶剂 Download PDFInfo
- Publication number
- CN1496272A CN1496272A CNA028063856A CN02806385A CN1496272A CN 1496272 A CN1496272 A CN 1496272A CN A028063856 A CNA028063856 A CN A028063856A CN 02806385 A CN02806385 A CN 02806385A CN 1496272 A CN1496272 A CN 1496272A
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- Prior art keywords
- component
- mms
- liter
- rise
- dialysis solutions
- Prior art date
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- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 title claims abstract description 120
- 238000000502 dialysis Methods 0.000 title description 23
- 238000002560 therapeutic procedure Methods 0.000 title description 6
- 239000012141 concentrate Substances 0.000 claims abstract description 98
- 239000003792 electrolyte Substances 0.000 claims abstract description 53
- 239000000203 mixture Substances 0.000 claims abstract description 22
- 239000000243 solution Substances 0.000 claims description 63
- 239000000385 dialysis solution Substances 0.000 claims description 52
- 238000000034 method Methods 0.000 claims description 48
- 239000011259 mixed solution Substances 0.000 claims description 39
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 34
- 239000011591 potassium Substances 0.000 claims description 34
- 229910052700 potassium Inorganic materials 0.000 claims description 34
- 239000011734 sodium Substances 0.000 claims description 30
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 28
- 229910052708 sodium Inorganic materials 0.000 claims description 28
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 23
- 239000012530 fluid Substances 0.000 claims description 23
- 229960001031 glucose Drugs 0.000 claims description 23
- 238000002156 mixing Methods 0.000 claims description 23
- 238000004891 communication Methods 0.000 claims description 19
- 238000012959 renal replacement therapy Methods 0.000 claims description 17
- 238000002615 hemofiltration Methods 0.000 claims description 14
- 230000035479 physiological effects, processes and functions Effects 0.000 claims description 13
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims description 12
- 239000011575 calcium Substances 0.000 claims description 12
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 10
- 229910052791 calcium Inorganic materials 0.000 claims description 10
- 239000011777 magnesium Substances 0.000 claims description 10
- 238000001802 infusion Methods 0.000 claims description 9
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 8
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 8
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 8
- 229910052749 magnesium Inorganic materials 0.000 claims description 8
- 230000015572 biosynthetic process Effects 0.000 claims description 6
- 238000012545 processing Methods 0.000 claims description 5
- 238000003860 storage Methods 0.000 claims description 4
- 238000011282 treatment Methods 0.000 abstract description 34
- 208000009304 Acute Kidney Injury Diseases 0.000 abstract description 12
- 208000033626 Renal failure acute Diseases 0.000 abstract description 12
- 201000011040 acute kidney failure Diseases 0.000 abstract description 12
- 208000012998 acute renal failure Diseases 0.000 abstract description 12
- 238000009472 formulation Methods 0.000 abstract description 5
- 208000028399 Critical Illness Diseases 0.000 abstract description 2
- 238000002360 preparation method Methods 0.000 description 67
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 22
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 21
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 16
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 15
- 210000004369 blood Anatomy 0.000 description 13
- 239000008280 blood Substances 0.000 description 13
- 208000024891 symptom Diseases 0.000 description 12
- 239000011780 sodium chloride Substances 0.000 description 11
- 239000001103 potassium chloride Substances 0.000 description 10
- 235000011164 potassium chloride Nutrition 0.000 description 10
- 238000001631 haemodialysis Methods 0.000 description 9
- -1 hydrogen salt Chemical class 0.000 description 8
- 239000001257 hydrogen Substances 0.000 description 7
- 229910052739 hydrogen Inorganic materials 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 6
- 238000000108 ultra-filtration Methods 0.000 description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 230000000322 hemodialysis Effects 0.000 description 4
- 230000036571 hydration Effects 0.000 description 4
- 238000006703 hydration reaction Methods 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 210000002381 plasma Anatomy 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 2
- 208000034486 Multi-organ failure Diseases 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- GZCGUPFRVQAUEE-SLPGGIOYSA-N aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O GZCGUPFRVQAUEE-SLPGGIOYSA-N 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 238000011975 continuous veno-venous hemodiafiltration Methods 0.000 description 2
- 238000011973 continuous veno-venous hemofiltration Methods 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 208000010718 Multiple Organ Failure Diseases 0.000 description 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 150000007516 brønsted-lowry acids Chemical class 0.000 description 1
- 150000007528 brønsted-lowry bases Chemical class 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 229910000042 hydrogen bromide Inorganic materials 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
- 229910000043 hydrogen iodide Inorganic materials 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 208000029744 multiple organ dysfunction syndrome Diseases 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000008174 sterile solution Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000001117 sulphuric acid Substances 0.000 description 1
- 235000011149 sulphuric acid Nutrition 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Abstract
Description
毫摩尔/升 | 制剂1 | 制剂2 | 制剂3 |
Na+ | 140 | 140 | 140 |
K+ | 0 | 2 | 4 |
Ca++ | 1.75 | 1.75 | 1.75 |
Mg++ | 0.5 | 0.5 | 0.5 |
Cl- | 109.5 | 111.5 | 113.5 |
HCO3 - | 35 | 35 | 35 |
无水右旋葡萄糖 | 0 | 5.55 | 5.55 |
克/升 | 制剂1 | 制剂2 | 制剂3 |
Na+ | 6.14 | 6.14 | 6.14 |
Ca++ | 0.257 | 0.257 | 0.257 |
Mg++ | 0.102 | 0.102 | 0.102 |
K+ | 0 | 0.149 | 0.298 |
HCO3 - | 2.94 | 2.94 | 2.94 |
无水右旋葡萄糖 | 0 | 1.0 | 1.0 |
或水合右旋葡萄糖 | 0 | 1.1 | 1.1 |
小室(克/升)(体积=906ml) | 制剂1 | 制剂2 | 制剂3 |
NaCl | 8.18 | 8.18 | 8.18 |
CaCl2.2H2O | 0.710 | 0.710 | 0.710 |
MgCl2.6H2O | 0.280 | 0.280 | 0.280 |
KCl | 0 | 0.411 | 0.822 |
无水右旋葡萄糖或水合右旋葡萄糖 | 00 | 2.763.03 | 2.763.03 |
(毫摩尔/升) | 制剂1 | 制剂2 | 制剂3 |
NaCl | 140 | 140 | 140 |
CaCl2.2H2O | 4.83 | 4.83 | 4.83 |
MgCl2.6H2O | 1.38 | 1.38 | 1.38 |
KCl | 0 | 5.52 | 11.0 |
无水右旋葡萄糖 | 0 | 5.55 | 5.55 |
大室(克/升)(体积=1594ml) | 制剂1 | 制剂2 | 制剂3 |
NaCl | 4.97 | 4.97 | 4.97 |
NaHCO3 | 4.61 | 4.61 | 4.61 |
(毫摩尔/升) | 制剂1 | 制剂2 | 制剂3 |
NaCl | 85.1 | 85.1 | 85.1 |
NaHCO3 | 54.9 | 54.9 | 54.9 |
测量的pH | |
小室(电解质) | 4.3-4.5 |
大室(缓冲液) | 7.4-7.6 |
混合溶液 | 7.2-7.3 |
小室(克/升)(体积=1125ml) | 制剂1 | 制剂2 | 制剂3 |
NaHCO3 | 13.4 | 13.4 | 13.4 |
NaOH | 0.520 | 0.520 | 0.520 |
(毫摩尔/升) | 制剂1 | 制剂2 | 制剂3 |
NaHCO3 | 160 | 160 | 160 |
NaOH | 13 | 13 | 13 |
大室(克/升)(体积=3375ml) | 制剂1 | 制剂2 | 制剂3 |
CaCl2.2H2O | 0.343 | 0.343 | 0.343 |
MgCl2.6H2O | 0.136 | 0.136 | 0.136 |
NaCl | 7.54 | 7.54 | 7.54 |
KCl | 0 | 0.199 | 0.397 |
无水右旋葡萄糖或水合右旋葡萄糖 | 00 | 1.331.46 | 1.331.46 |
HCl | 0.401 | 0.401 | 0.401 |
(毫摩尔/升) | 制剂1 | 制剂2 | 制剂3 |
CaCl2.2H2O | 2.33 | 2.33 | 2.33 |
MgCl2.6H2O | 0.667 | 0.667 | 0.667 |
NaCl | 129 | 129 | 129 |
KCl | 0 | 2.67 | 5.33 |
无水右旋葡萄糖 | 0 | 7.40 | 7.40 |
HCl | 11 | 11 | 11 |
测量的pH | |
小室(缓冲液) | 8.9-9.0 |
大室(电解质) | 1.9 |
混合溶液 | 7.1-7.3 |
Claims (64)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/044,234 US7122210B2 (en) | 2002-01-11 | 2002-01-11 | Bicarbonate-based solutions for dialysis therapies |
US10/044,234 | 2002-01-11 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2007103053034A Division CN101219151A (zh) | 2002-01-11 | 2002-11-04 | 用于透析治疗的碳酸氢盐基溶剂 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1496272A true CN1496272A (zh) | 2004-05-12 |
CN100367942C CN100367942C (zh) | 2008-02-13 |
Family
ID=21931220
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB028063856A Expired - Fee Related CN100367942C (zh) | 2002-01-11 | 2002-11-04 | 用于透析治疗的碳酸氢盐基溶剂 |
CNA2007103053034A Pending CN101219151A (zh) | 2002-01-11 | 2002-11-04 | 用于透析治疗的碳酸氢盐基溶剂 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2007103053034A Pending CN101219151A (zh) | 2002-01-11 | 2002-11-04 | 用于透析治疗的碳酸氢盐基溶剂 |
Country Status (16)
Country | Link |
---|---|
US (2) | US7122210B2 (zh) |
EP (3) | EP2322236B2 (zh) |
JP (2) | JP4778681B2 (zh) |
KR (4) | KR101119334B1 (zh) |
CN (2) | CN100367942C (zh) |
AR (1) | AR038113A1 (zh) |
AT (1) | ATE539782T1 (zh) |
AU (1) | AU2002356899B2 (zh) |
BR (1) | BR0208003A (zh) |
CA (1) | CA2440455A1 (zh) |
DK (3) | DK2322237T3 (zh) |
ES (3) | ES2395369T5 (zh) |
HK (1) | HK1065966A1 (zh) |
MX (1) | MXPA03008204A (zh) |
TW (1) | TWI326597B (zh) |
WO (1) | WO2003059417A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101522231B (zh) * | 2006-04-21 | 2013-03-13 | 日本多宁股份有限公司 | 透析溶液制备用水、使用这种水的透析溶液、生产透析溶液的方法和透析设备 |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7122210B2 (en) * | 2002-01-11 | 2006-10-17 | Baxter International Inc. | Bicarbonate-based solutions for dialysis therapies |
US7052480B2 (en) | 2002-04-10 | 2006-05-30 | Baxter International Inc. | Access disconnection systems and methods |
US20040254513A1 (en) | 2002-04-10 | 2004-12-16 | Sherwin Shang | Conductive polymer materials and applications thereof including monitoring and providing effective therapy |
US7022098B2 (en) | 2002-04-10 | 2006-04-04 | Baxter International Inc. | Access disconnection systems and methods |
US10155082B2 (en) * | 2002-04-10 | 2018-12-18 | Baxter International Inc. | Enhanced signal detection for access disconnection systems |
DE102004023828A1 (de) * | 2004-05-13 | 2005-12-08 | Fresenius Medical Care Deutschland Gmbh | Lösung für die Peritonealdialyse |
US7384558B2 (en) | 2004-07-26 | 2008-06-10 | Baxter International Inc. | Compositions capable of inhibiting reactive oxygen and carbonyl species |
SE0402507D0 (sv) | 2004-10-14 | 2004-10-14 | Gambro Lundia Ab | Medicinsk lösning, förfarande för framställning och användning därav |
US7935070B2 (en) | 2005-01-28 | 2011-05-03 | Fresenius Medical Care North America | Systems and methods for dextrose containing peritoneal dialysis (PD) solutions with neutral pH and reduced glucose degradation product |
US20070075714A1 (en) * | 2005-09-29 | 2007-04-05 | Dollinger Harli M | Dual-chamber solution packaging system |
US10537671B2 (en) | 2006-04-14 | 2020-01-21 | Deka Products Limited Partnership | Automated control mechanisms in a hemodialysis apparatus |
US7794141B2 (en) | 2006-04-14 | 2010-09-14 | Deka Products Limited Partnership | Thermal and coductivity sensing systems, devices and methods |
US9717834B2 (en) | 2011-05-24 | 2017-08-01 | Deka Products Limited Partnership | Blood treatment systems and methods |
US8366316B2 (en) * | 2006-04-14 | 2013-02-05 | Deka Products Limited Partnership | Sensor apparatus systems, devices and methods |
KR101861192B1 (ko) | 2007-02-27 | 2018-05-28 | 데카 프로덕츠 리미티드 파트너쉽 | 혈액투석 장치 및 방법 |
US8042563B2 (en) | 2007-02-27 | 2011-10-25 | Deka Products Limited Partnership | Cassette system integrated apparatus |
US8409441B2 (en) | 2007-02-27 | 2013-04-02 | Deka Products Limited Partnership | Blood treatment systems and methods |
US8317492B2 (en) | 2007-02-27 | 2012-11-27 | Deka Products Limited Partnership | Pumping cassette |
US8425471B2 (en) | 2007-02-27 | 2013-04-23 | Deka Products Limited Partnership | Reagent supply for a hemodialysis system |
US8562834B2 (en) | 2007-02-27 | 2013-10-22 | Deka Products Limited Partnership | Modular assembly for a portable hemodialysis system |
US8393690B2 (en) | 2007-02-27 | 2013-03-12 | Deka Products Limited Partnership | Enclosure for a portable hemodialysis system |
US20090107335A1 (en) | 2007-02-27 | 2009-04-30 | Deka Products Limited Partnership | Air trap for a medical infusion device |
US9028691B2 (en) | 2007-02-27 | 2015-05-12 | Deka Products Limited Partnership | Blood circuit assembly for a hemodialysis system |
US8491184B2 (en) | 2007-02-27 | 2013-07-23 | Deka Products Limited Partnership | Sensor apparatus systems, devices and methods |
US8357298B2 (en) | 2007-02-27 | 2013-01-22 | Deka Products Limited Partnership | Hemodialysis systems and methods |
US8771508B2 (en) | 2008-08-27 | 2014-07-08 | Deka Products Limited Partnership | Dialyzer cartridge mounting arrangement for a hemodialysis system |
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