DE122007000035I2 - 5-alkyl-2-arylaminophenylessigsäure und derivative - Google Patents

5-alkyl-2-arylaminophenylessigsäure und derivative

Info

Publication number
DE122007000035I2
DE122007000035I2 DE122007000035C DE122007000035C DE122007000035I2 DE 122007000035 I2 DE122007000035 I2 DE 122007000035I2 DE 122007000035 C DE122007000035 C DE 122007000035C DE 122007000035 C DE122007000035 C DE 122007000035C DE 122007000035 I2 DE122007000035 I2 DE 122007000035I2
Authority
DE
Germany
Prior art keywords
derivatives
alkyl
arylaminophenylacetic acid
arylaminophenylacetic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE122007000035C
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26736901&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122007000035(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE122007000035I2 publication Critical patent/DE122007000035I2/de
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
DE122007000035C 1997-08-28 1998-08-26 5-alkyl-2-arylaminophenylessigsäure und derivative Active DE122007000035I2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US6983797P 1997-08-28 1997-08-28
US5780397P 1997-08-28 1997-08-28
DE69813570T DE69813570T2 (de) 1997-08-28 1998-08-26 5-alkyl-2-arylaminophenylessigsäure und derivative
PCT/EP1998/005414 WO1999011605A1 (en) 1997-08-28 1998-08-26 Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives

Publications (1)

Publication Number Publication Date
DE122007000035I2 true DE122007000035I2 (de) 2010-07-01

Family

ID=26736901

Family Applications (4)

Application Number Title Priority Date Filing Date
DE69813570T Expired - Lifetime DE69813570T2 (de) 1997-08-28 1998-08-26 5-alkyl-2-arylaminophenylessigsäure und derivative
DE122007000035C Active DE122007000035I2 (de) 1997-08-28 1998-08-26 5-alkyl-2-arylaminophenylessigsäure und derivative
DE1998613570 Pending DE122007000035I1 (de) 1997-08-28 1998-08-26 5-Alkyl-2-Arylaminophenylessigs{ure und derivative
DE122009000013C Pending DE122009000013I1 (de) 1997-08-28 1998-08-26 5-alkyl-2-arylaminophenylessigsäure und derivative

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69813570T Expired - Lifetime DE69813570T2 (de) 1997-08-28 1998-08-26 5-alkyl-2-arylaminophenylessigsäure und derivative

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE1998613570 Pending DE122007000035I1 (de) 1997-08-28 1998-08-26 5-Alkyl-2-Arylaminophenylessigs{ure und derivative
DE122009000013C Pending DE122009000013I1 (de) 1997-08-28 1998-08-26 5-alkyl-2-arylaminophenylessigsäure und derivative

Country Status (35)

Country Link
US (5) US6291523B1 (de)
EP (1) EP1007505B1 (de)
JP (1) JP3704470B2 (de)
KR (1) KR100637296B1 (de)
CN (1) CN1140500C (de)
AR (1) AR015157A1 (de)
AT (1) ATE237580T1 (de)
AU (1) AU743371B2 (de)
BR (1) BR9812010B1 (de)
CA (1) CA2298033C (de)
CO (1) CO4960662A1 (de)
CY (1) CY2007020I2 (de)
CZ (1) CZ298522B6 (de)
DE (4) DE69813570T2 (de)
DK (1) DK1007505T3 (de)
ES (1) ES2197508T3 (de)
FR (1) FR09C0011I2 (de)
HK (1) HK1031374A1 (de)
HU (1) HU225774B1 (de)
ID (1) ID23953A (de)
IL (2) IL134498A0 (de)
LU (2) LU91346I2 (de)
MY (1) MY127881A (de)
NL (1) NL300379I2 (de)
NO (2) NO326196B1 (de)
NZ (1) NZ502669A (de)
PE (1) PE108099A1 (de)
PL (1) PL194480B1 (de)
PT (1) PT1007505E (de)
RU (1) RU2186762C2 (de)
SI (1) SI1007505T1 (de)
SK (1) SK283773B6 (de)
TR (1) TR200000447T2 (de)
TW (1) TWI250142B (de)
WO (1) WO1999011605A1 (de)

Families Citing this family (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
CO4960662A1 (es) * 1997-08-28 2000-09-25 Novartis Ag Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados
JP2002528498A (ja) * 1998-11-02 2002-09-03 メルク エンド カムパニー インコーポレーテッド 片頭痛の治療方法及び医薬組成物
US20040053900A1 (en) * 1998-12-23 2004-03-18 Pharmacia Corporation Method of using a COX-2 inhibitor and an aromatase inhibitor as a combination therapy
US20040122011A1 (en) * 1998-12-23 2004-06-24 Pharmacia Corporation Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
GB9922830D0 (en) * 1999-09-27 1999-11-24 Novartis Ag Processes
PE20020351A1 (es) * 2000-09-11 2002-06-14 Novartis Ag Composiciones farmaceuticas que comprenden acido 5-metil-2-(2'-cloro-6'-fluoroanilino)fenilacetico como inhibidor de la ciclooxigenasa-2
AU2001216038A1 (en) * 2000-11-14 2002-05-27 Alcon Laboratories Inc. Treatment of glaucoma and ocular hypertension
US7656959B2 (en) 2001-04-13 2010-02-02 Agere Systems Inc. Pipelined decision-feedback unit in a reduced-state viterbi detector with local feedback
US20050264906A1 (en) * 2004-05-25 2005-12-01 Haratsch Erich F Method and apparatus for reduced-state Viterbi detection in a read channel of a magnetic recording system
DE10129320A1 (de) * 2001-06-19 2003-04-10 Norbert Mueller Verwendung von COX-2 Inhibitoren zur Behandlung von Schizophrenie, wahnhaften Störungen, affektiven Störungen oder Ticstörungen
US20060167074A1 (en) * 2001-06-19 2006-07-27 Norbert Muller Methods and compositions for the treatment of psychiatric disorders
PE20030323A1 (es) * 2001-08-31 2003-05-12 Novartis Ag Composicion farmaceutica
EP1436259A1 (de) 2001-09-10 2004-07-14 Congxin Liang 3-(4,5,6,7-tetrahydroindol-2-yl methylidien)-2-indolinonderivate als kinaseinhibitoren
US7504231B2 (en) * 2001-09-13 2009-03-17 The Board Of Regents Of The University Of Oklahoma Method of alleviating chronic pain via peripheral inhibition of neurotransmitter synthesis
EP1434576A4 (de) 2001-09-13 2006-03-29 Kenneth E Miller Verfahren zur linderung von schmerzen
GB0124459D0 (en) * 2001-10-11 2001-12-05 Novartis Ag Organic compounds
PL369305A1 (en) * 2001-10-25 2005-04-18 Novartis Ag Combinations comprising a selective cyclooxygenase-2 inhibitor
HUP0402370A3 (en) * 2001-11-06 2008-04-28 Novartis Ag Pharmaceutical compositions containing cyclooxigenase-2 inhibitor and histone deacetylase inhibitor combination
US20030212138A1 (en) * 2002-01-14 2003-11-13 Pharmacia Corporation Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
US20030220374A1 (en) * 2002-01-14 2003-11-27 Pharmacia Corporation Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
GB0201520D0 (en) * 2002-01-23 2002-03-13 Novartis Ag Pharmaceutical uses
CA2476744A1 (en) * 2002-03-07 2003-09-12 Novartis Ag Solid pharmaceutical compositions comprising lumiracoxib
GB0209257D0 (en) * 2002-04-23 2002-06-05 Novartis Ag Organic compounds
WO2003103602A2 (en) * 2002-06-11 2003-12-18 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
ITMI20021391A1 (it) 2002-06-25 2003-12-29 Nicox Sa Nitroderivati di inibitori della cicloossigenasi-2
CA2492989C (en) 2002-07-23 2012-11-20 Novartis Ag Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent
UY27939A1 (es) 2002-08-21 2004-03-31 Glaxo Group Ltd Compuestos
AU2003294221A1 (en) * 2002-09-13 2004-04-19 Kenneth E. Miller Method of alleviating pain via inhibition of neurotransmitter synthesis
GB0224198D0 (en) * 2002-10-17 2002-11-27 Novartis Ag Organic compounds
US7632866B2 (en) * 2002-10-21 2009-12-15 Ramot At Tel Aviv University Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
AR042206A1 (es) 2002-11-26 2005-06-15 Novartis Ag Acidos fenilaceticos y derivados
US20040204411A1 (en) * 2002-12-17 2004-10-14 Pharmacia Corporation Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of reboxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
AU2003294883A1 (en) * 2002-12-18 2004-07-09 Novartis Ag Combinations of valsartan with cox-2 inhibitors
US7157577B2 (en) 2003-03-07 2007-01-02 Sugen Inc. 5-sulfonamido-substituted indolinone compounds as protein kinase inhibitors
TWI327913B (en) * 2003-03-12 2010-08-01 Novartis Ag Pharmaceutical composition comprising 5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid
US20040220155A1 (en) * 2003-03-28 2004-11-04 Pharmacia Corporation Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
SE0301010D0 (sv) 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
US20060135506A1 (en) * 2003-04-22 2006-06-22 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a calcium modulating agent for the treatment of pain, inflammation or inflammation mediated disorders
WO2004093816A2 (en) * 2003-04-22 2004-11-04 Pharmacia Corporation Compositions comprising a selective cox-2 inhibitor and a calcium modulating agent
US20040220187A1 (en) * 2003-04-22 2004-11-04 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a sodium ion channel blocker for the treatment of pain, inflammation or inflammation mediated disorders
US20040229803A1 (en) * 2003-04-22 2004-11-18 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a potassium ion channel modulator for the treatment of pain, inflammation or inflammation mediated disorders
ATE342722T1 (de) 2003-05-07 2006-11-15 Osteologix As Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen
WO2004100895A2 (en) * 2003-05-13 2004-11-25 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a peroxisome proliferator activated receptor agonist for the treatment of ischemic mediated central nervous system disorders
WO2004103286A2 (en) * 2003-05-14 2004-12-02 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a cholimergic agent
US7220422B2 (en) * 2003-05-20 2007-05-22 Allergan, Inc. Methods and compositions for treating eye disorders
US20060160776A1 (en) * 2003-05-28 2006-07-20 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage
WO2005007106A2 (en) * 2003-07-10 2005-01-27 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a non-nmda glutamate modulator for the treatment of central nervous system damage
WO2005009342A2 (en) * 2003-07-16 2005-02-03 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
WO2005009354A2 (en) * 2003-07-17 2005-02-03 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and an ikk inhibitor for the treatment of ischemic-mediated central nervous system disorders or injury
SA04250253B1 (ar) 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
US20050119262A1 (en) * 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
WO2005018563A2 (en) * 2003-08-22 2005-03-03 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a phosphodiesterase inhibitor for the treatment of ischemic mediated central nervous system disorders or injury
WO2005023189A2 (en) * 2003-09-03 2005-03-17 Pharmacia Corporation Method of cox-2 selective inhibitor and nitric oxide-donating agent
WO2005037193A2 (en) * 2003-10-03 2005-04-28 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor administered under hypothermic conditions for the treatment of ischemic mediated central nervous system disorders or injury
US20070123593A1 (en) * 2003-10-08 2007-05-31 Rose-Marie Dannenfelser Pharmaceutical composition comprising 5-methyl-2(2'-chloro-6'-fluoroanilino)phenylacetic acid
BRPI0415939A (pt) * 2003-11-12 2007-01-02 Pharmacia & Upjohn Co Llc composições de um inibidor seletivo da ciclooxigenase-2 e um agente de modulação do fator neurotrófico para o tratamento de distúrbios mediados pelo sistema nervoso central
KR101142583B1 (ko) 2004-01-07 2012-05-11 세이가가쿠 고교 가부시키가이샤 히알루론산 유도체 및 그것을 포함하는 약제
CA2559915C (en) 2004-03-23 2013-07-02 Novartis Ag Micronization of pharmaceutically active agents
TW200603792A (en) * 2004-04-23 2006-02-01 Pharmacia & Upjohn Co Llc Monotherapy for the treatment of psoriasis with cyclooxygenase-2 selective inhibitors
US7380199B2 (en) * 2004-05-25 2008-05-27 Agere Systems Inc. Method and apparatus for precomputation and pipelined selection of branch metrics in a reduced-state Viterbi detector
US7653154B2 (en) * 2004-05-25 2010-01-26 Agere Systems Inc. Method and apparatus for precomputation and pipelined selection of intersymbol interference estimates in a reduced-state Viterbi detector
US7487432B2 (en) * 2004-05-25 2009-02-03 Agere Systems Inc. Method and apparatus for multiple step Viterbi detection with local feedback
GB0415320D0 (en) 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
GB0416508D0 (en) * 2004-07-23 2004-08-25 Merck Sharp & Dohme Therapeutic agents
GB0418830D0 (en) 2004-08-24 2004-09-22 Astrazeneca Ab Novel compounds
DE102004044827A1 (de) * 2004-09-16 2006-03-23 Bayer Cropscience Ag Jod-phenylsubstituierte cyclische Ketoenole
JP5208510B2 (ja) 2004-11-23 2013-06-12 アストラゼネカ・アクチエボラーグ 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体
BRPI0519398A2 (pt) 2004-12-23 2009-01-20 Glaxo Group Ltd compostos de piridina para o tratamento de doenÇas mediadas por prostaglandina
CA2598645A1 (en) * 2005-02-22 2006-08-31 Merial Limited Methods for selectively treating cox-2 mediated disorders by administering gamma-tocopherol
CA2604357C (en) 2005-04-26 2012-01-17 Pfizer Inc. P-cadherin antibodies
US20060251702A1 (en) * 2005-05-05 2006-11-09 Cook Biotech Incorporated Implantable materials and methods for inhibiting tissue adhesion formation
AU2006297571B2 (en) 2005-09-07 2012-03-15 Amgen Fremont Inc. Human monoclonal antibodies to activin receptor-like kinase-1
TW200745003A (en) 2005-10-06 2007-12-16 Astrazeneca Ab Novel compounds
EP1937632A1 (de) 2005-10-06 2008-07-02 Astra Zeneca AB Neue verbindungen
JP2007275193A (ja) * 2006-04-04 2007-10-25 Fujifilm Corp 光プローブおよび光断層画像化装置
AR061623A1 (es) * 2006-06-26 2008-09-10 Novartis Ag Derivados de acido fenilacetico
GB0704407D0 (en) 2007-03-07 2007-04-18 Glaxo Group Ltd Compounds
UA100983C2 (ru) 2007-07-05 2013-02-25 Астразенека Аб Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
US7943658B2 (en) * 2007-07-23 2011-05-17 Bristol-Myers Squibb Company Indole indane amide compounds useful as CB2 agonists and method
US8765815B2 (en) * 2007-09-20 2014-07-01 Ramot At Tel-Aviv University Ltd. N-phenyl anthranilic acid derivatives and uses thereof
US20090082452A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lumiracoxib
CN101952244B (zh) 2008-02-01 2014-11-05 潘米拉制药公司 前列腺素d2受体的n,n-二取代氨基烷基联苯拮抗剂
WO2009102893A2 (en) 2008-02-14 2009-08-20 Amira Pharmaceuticals, Inc. CYCLIC DIARYL ETHER COMPOUNDS AS ANTAGONISTS OF PROSTAGLANDIN D2 receptors
EP2245022A4 (de) 2008-02-25 2012-02-22 Panmira Pharmaceuticals Llc Antagonisten von prostaglandin-d2-rezeptoren
JP2011518130A (ja) 2008-04-02 2011-06-23 アミラ ファーマシューティカルズ,インク. プロスタグランジンd2受容体のアミノアルキルフェニルアンタゴニスト
PE20100094A1 (es) * 2008-07-03 2010-02-18 Amira Pharmaceuticals Inc Antagonistas heteroalquilo de receptores de prostaglandina d2
GB0813142D0 (en) 2008-07-17 2008-08-27 Glaxo Group Ltd Novel compounds
GB0813144D0 (en) 2008-07-17 2008-08-27 Glaxo Group Ltd Novel compounds
GB2463788B (en) 2008-09-29 2010-12-15 Amira Pharmaceuticals Inc Heteroaryl antagonists of prostaglandin D2 receptors
US8378107B2 (en) 2008-10-01 2013-02-19 Panmira Pharmaceuticals, Llc Heteroaryl antagonists of prostaglandin D2 receptors
WO2010042652A2 (en) 2008-10-08 2010-04-15 Amira Pharmaceuticals, Inc. Heteroalkyl biphenyl antagonists of prostaglandin d2 receptors
EP2177215A1 (de) 2008-10-17 2010-04-21 Laboratorios Del. Dr. Esteve, S.A. Co-Kristalle von Tramadol und NSARs
US8227451B2 (en) * 2008-11-12 2012-07-24 Auspex Pharmaceuticals Phenylacetic acid inhibitors of cyclooxygenase
US8383654B2 (en) 2008-11-17 2013-02-26 Panmira Pharmaceuticals, Llc Heterocyclic antagonists of prostaglandin D2 receptors
WO2011012622A1 (en) 2009-07-30 2011-02-03 Glaxo Group Limited Benzoxazinone derivatives for the treatment of glytl mediated disorders
WO2011014587A2 (en) 2009-07-31 2011-02-03 Amira Pharmaceuticals, Inc. Ophthalmic pharmaceutical compositions of dp2 receptor antagonists
US8815917B2 (en) 2009-08-05 2014-08-26 Panmira Pharmaceuticals, Llc DP2 antagonist and uses thereof
WO2011023753A1 (en) 2009-08-27 2011-03-03 Glaxo Group Limited Benzoxazine derivatives as glycine transport inhibitors
JP2013516475A (ja) 2010-01-06 2013-05-13 アミラ ファーマシューティカルズ,インク. Dp2アンタゴニストおよびその使用
GB201000685D0 (en) 2010-01-15 2010-03-03 Glaxo Group Ltd Novel compounds
GB201007789D0 (en) 2010-05-10 2010-06-23 Glaxo Group Ltd Novel Compound
GB201007791D0 (en) 2010-05-10 2010-06-23 Glaxo Group Ltd Novel compounds
EP2590953B1 (de) 2010-07-09 2014-10-29 Convergence Pharmaceuticals Limited Tetrazolverbindungen als calciumkanalblocker
US8892989B1 (en) * 2010-08-26 2014-11-18 Clearslide, Inc. Method for searching companies and people
US20120090486A1 (en) 2010-10-18 2012-04-19 Celin Savariar-Hauck Lithographic printing plate precursors and methods of use
US8900798B2 (en) 2010-10-18 2014-12-02 Eastman Kodak Company On-press developable lithographic printing plate precursors
US20120141942A1 (en) 2010-12-03 2012-06-07 Domenico Balbinot Method of preparing lithographic printing plates
US20120141935A1 (en) 2010-12-03 2012-06-07 Bernd Strehmel Developer and its use to prepare lithographic printing plates
US20120141941A1 (en) 2010-12-03 2012-06-07 Mathias Jarek Developing lithographic printing plate precursors in simple manner
ES2541416T3 (es) 2011-01-19 2015-07-20 Convergence Pharmaceuticals Limited Derivados de piperazina como bloqueadores de los canales de calcio Cav2.2
US20120199028A1 (en) 2011-02-08 2012-08-09 Mathias Jarek Preparing lithographic printing plates
AR087814A1 (es) 2011-09-16 2014-04-16 Fovea Pharmaceuticals Derivados de anilina, su preparacion y su aplicacion terapeutica
US9029063B2 (en) 2011-09-22 2015-05-12 Eastman Kodak Company Negative-working lithographic printing plate precursors
US8632941B2 (en) 2011-09-22 2014-01-21 Eastman Kodak Company Negative-working lithographic printing plate precursors with IR dyes
CN102311355B (zh) * 2011-09-26 2014-02-05 扬州天和药业有限公司 罗本考昔的一种制备方法
GB201122113D0 (en) 2011-12-22 2012-02-01 Convergence Pharmaceuticals Novel compounds
US8679726B2 (en) 2012-05-29 2014-03-25 Eastman Kodak Company Negative-working lithographic printing plate precursors
US9063423B2 (en) 2013-02-28 2015-06-23 Eastman Kodak Company Lithographic printing plate precursors and use
US9201302B2 (en) 2013-10-03 2015-12-01 Eastman Kodak Company Negative-working lithographic printing plate precursor
GB201417499D0 (en) 2014-10-03 2014-11-19 Convergence Pharmaceuticals Novel use
GB201417500D0 (en) 2014-10-03 2014-11-19 Convergence Pharmaceuticals Novel use
GB201417497D0 (en) 2014-10-03 2014-11-19 Convergence Pharmaceuticals Novel use
KR20190111142A (ko) 2017-03-14 2019-10-01 세이가가쿠 고교 가부시키가이샤 관절 질환 처치용 조성물 및 그것을 포함하는 키트
CA3051663A1 (en) 2017-03-14 2018-09-20 Seikagaku Corporation Composition for treating joint diseases and kit including same
KR102069205B1 (ko) 2017-08-09 2020-01-22 연성정밀화학(주) 라타노프로스틴 부노드의 제조 방법 및 그를 위한 중간체
CN109694330B (zh) * 2017-10-24 2023-10-20 乳源瑶族自治县东阳光生物科技有限公司 一种酸的制备方法
EP3830072A1 (de) 2018-07-27 2021-06-09 KRKA, d.d., Novo mesto Verfahren zur herstellung einer polymorphen form von robenacoxib
CN109503399B (zh) * 2018-12-29 2021-12-24 江苏天和制药有限公司 一种罗本考昔的制备方法
CN110437090A (zh) * 2019-07-31 2019-11-12 江苏天和制药有限公司 一种罗本考昔三聚体及其制备方法
CN111807978B (zh) * 2020-07-29 2023-03-14 武汉川泰科技有限公司 一种罗贝考昔的制备方法
IL305573A (en) 2021-03-15 2023-10-01 Saul Yedgar Hyaluronic acid conjugated with dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment or suppression of inflammatory diseases
EP4281183A1 (de) 2022-03-23 2023-11-29 Alivira Animal Health Limited Verbessertes verfahren zur reinigung von robenacoxib

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558690A (en) 1965-04-08 1971-01-26 Gelgy Chemical Corp Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation
US3895063A (en) 1965-04-08 1975-07-15 Ciba Geigy Corp Substituted Anilino Benzyl Alcohols
GB1166861A (en) 1966-01-15 1969-10-15 Aspro Nicholas Ltd New Diphenylamine Derivatives and Compositions containing them
US3652762A (en) 1970-04-14 1972-03-28 Ciba Geigy Corp Pharmaceutical compositions and methods employing substituted derivatives of 2-anilinophenylacetic acids and esters
US4173577A (en) 1970-09-09 1979-11-06 Ciba-Geigy Corporation Phenylacetohydroxamic acids
ES520813A0 (es) 1983-03-21 1984-05-16 Prodes Sa Procedimiento para la obtencion del ester del acido 2-(2,6-diclorofenil)amino bencenoacetico con acido glicolico.
DE3445011A1 (de) 1983-12-13 1985-06-13 Ciba-Geigy Ag, Basel Neues anilinderivat, verfahren zu seiner herstellung und seine verwendung
IT1256345B (it) 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
US5708024A (en) 1994-06-29 1998-01-13 Novartis Corporation Salts of 2- (2,6-dichlorophenyl)amine!phenylacetoxyacetic acid with organic basic cations
JPH0977664A (ja) 1995-09-13 1997-03-25 Yakult Honsha Co Ltd シクロオキシゲナーゼ−2特異的阻害剤及び抗炎症剤
CO4960662A1 (es) 1997-08-28 2000-09-25 Novartis Ag Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados

Also Published As

Publication number Publication date
MY127881A (en) 2006-12-29
JP3704470B2 (ja) 2005-10-12
FR09C0011I2 (de) 2011-04-01
RU2186762C2 (ru) 2002-08-10
DE122009000013I1 (de) 2009-06-25
SK283773B6 (sk) 2004-01-08
EP1007505A1 (de) 2000-06-14
US20040122254A1 (en) 2004-06-24
US7115662B2 (en) 2006-10-03
NZ502669A (en) 2002-02-01
EP1007505B1 (de) 2003-04-16
HUP0002514A2 (hu) 2000-12-28
AU743371B2 (en) 2002-01-24
ID23953A (id) 2000-06-08
IL134498A (en) 2009-06-15
CO4960662A1 (es) 2000-09-25
BR9812010B1 (pt) 2010-12-14
AU9534098A (en) 1999-03-22
SI1007505T1 (en) 2003-10-31
WO1999011605A8 (en) 2000-03-02
US20020183391A1 (en) 2002-12-05
PE108099A1 (es) 1999-11-18
LU91346I2 (fr) 2007-09-11
US6291523B1 (en) 2001-09-18
NL300379I1 (nl) 2009-05-06
CA2298033C (en) 2007-10-02
US20020013369A1 (en) 2002-01-31
BR9812010A (pt) 2000-12-12
HU225774B1 (en) 2007-08-28
TR200000447T2 (tr) 2000-07-21
KR20010023344A (ko) 2001-03-26
US6451858B2 (en) 2002-09-17
FR09C0011I1 (de) 2009-04-17
JP2001514244A (ja) 2001-09-11
AR015157A1 (es) 2001-04-18
PL194480B1 (pl) 2007-06-29
ES2197508T3 (es) 2004-01-01
ATE237580T1 (de) 2003-05-15
CA2298033A1 (en) 1999-03-11
CN1268112A (zh) 2000-09-27
NO326196B1 (no) 2008-10-13
DE69813570T2 (de) 2004-02-12
NO20000943L (no) 2000-02-25
CN1140500C (zh) 2004-03-03
PL338357A1 (en) 2000-10-23
SK2472000A3 (en) 2000-09-12
TWI250142B (en) 2006-03-01
KR100637296B1 (ko) 2006-10-23
DE122007000035I1 (de) 2007-07-19
HK1031374A1 (en) 2001-06-15
WO1999011605A1 (en) 1999-03-11
NO20000943D0 (no) 2000-02-25
PT1007505E (pt) 2003-08-29
CY2007020I1 (el) 2012-01-25
LU91540I2 (fr) 2009-05-11
US6310099B1 (en) 2001-10-30
DK1007505T3 (da) 2003-07-21
CZ2000714A3 (cs) 2000-06-14
NO2009007I2 (no) 2010-06-07
NL300379I2 (nl) 2010-02-01
DE69813570D1 (de) 2003-05-22
IL134498A0 (en) 2001-04-30
NO2009007I1 (no) 2009-04-06
US6727281B2 (en) 2004-04-27
CZ298522B6 (cs) 2007-10-24
CY2007020I2 (el) 2012-01-25
HUP0002514A3 (en) 2002-11-28

Similar Documents

Publication Publication Date Title
ATE237580T1 (de) 5-alkyl-2-arylaminophenylessigsäure und derivative
ATE248812T1 (de) Arylsulfonylhydroxamsäurederivate
DK1003720T3 (da) Aryloxyarylsulfonylaminohydroxamsyrederivater
DE69703385D1 (de) Alkoxyessigsäure-derivate
NO990821D0 (no) Arylsulfonylamino-hydroksaminsyre-derivater
ATE260243T1 (de) N-aroylphenylalaninderivate
ATE235220T1 (de) Resorcinderivate
EE03765B1 (et) Propioonhappe derivaadid ja nende kasutamine
ID22781A (id) Turunan-turunan nikotinamida
DE69817186D1 (de) Diaminorhodamin-derivate
ATE211131T1 (de) Arylsulfonylaminohydroxamsäurederivate
DE69720051T2 (de) Harnstoffderivate
NO20000231D0 (no) Dolastatin-15-derivater
PT1003719E (pt) Derivados microbicidas de n-sulfonil-glicinalquiniloxifenemetilamida
PT1027362E (pt) Derivados de cetolidos 2-halogeno-6-o-substituidos
DE69841086D1 (de) 5-Deoxy-Cytidin-Derivate
DE69718338D1 (de) 3-alkoxyisoxazol-4-yl-substituierte 2-aminocarbonsäurederivate
ATE292632T1 (de) Cis-disubstituierte aminocycloalkyl-pyrrolidin- derivate
DE69828780D1 (de) Amidinocamptpthecin-derivate
NO981495L (no) Fenoksymetylpiperidin-derivater
DK0966437T3 (da) 5-Aroylnaphthalenderivater
NO994386D0 (no) 2-substituerte benzoylcykloalkyl-1-karboksylsyrederivater
EE04061B1 (et) Metüleenbisfosfoonhappe derivaadid
DK1015447T3 (da) Piperidinylmethyloxazolidinonderivat
DE69711853D1 (de) Pyridincarboxamid-derivate