DE3167436D1 - Concentrating zone method in heterogeneous immunoassays - Google Patents

Concentrating zone method in heterogeneous immunoassays

Info

Publication number
DE3167436D1
DE3167436D1 DE8181302826T DE3167436T DE3167436D1 DE 3167436 D1 DE3167436 D1 DE 3167436D1 DE 8181302826 T DE8181302826 T DE 8181302826T DE 3167436 T DE3167436 T DE 3167436T DE 3167436 D1 DE3167436 D1 DE 3167436D1
Authority
DE
Germany
Prior art keywords
zone
signal
immunosorbing
mip
zone method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181302826T
Other languages
English (en)
Inventor
Henry Kork Tom
Gerald Leroy Rowley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Syva Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syva Co filed Critical Syva Co
Application granted granted Critical
Publication of DE3167436D1 publication Critical patent/DE3167436D1/de
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/805—Test papers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
DE8181302826T 1980-08-07 1981-06-23 Concentrating zone method in heterogeneous immunoassays Expired DE3167436D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/176,177 US4366241A (en) 1980-08-07 1980-08-07 Concentrating zone method in heterogeneous immunoassays

Publications (1)

Publication Number Publication Date
DE3167436D1 true DE3167436D1 (en) 1985-01-10

Family

ID=22643311

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181302826T Expired DE3167436D1 (en) 1980-08-07 1981-06-23 Concentrating zone method in heterogeneous immunoassays

Country Status (9)

Country Link
US (1) US4366241A (de)
EP (1) EP0046004B1 (de)
JP (3) JPS5763454A (de)
AT (1) ATE10548T1 (de)
CA (1) CA1174595A (de)
DE (1) DE3167436D1 (de)
HK (1) HK15887A (de)
MY (1) MY8700300A (de)
SG (1) SG89186G (de)

Families Citing this family (1191)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) * 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
US6630328B2 (en) 1909-07-15 2003-10-07 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms
US5432057A (en) * 1979-12-26 1995-07-11 Syva Company Simultaneous calibration heterogeneous immunoassay
US4540659A (en) * 1981-04-17 1985-09-10 Syva Company Simultaneous calibration heterogeneous immunoassay
US4533629A (en) * 1981-04-17 1985-08-06 Syva Company Simultaneous calibration heterogeneous immunoassay
US4843000A (en) * 1979-12-26 1989-06-27 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4299916A (en) * 1979-12-26 1981-11-10 Syva Company Preferential signal production on a surface in immunoassays
US4849338A (en) * 1982-07-16 1989-07-18 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US5156953A (en) * 1979-12-26 1992-10-20 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
JPS5782766A (en) * 1980-11-11 1982-05-24 Konishiroku Photo Ind Co Ltd Amynological measuring element
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4752562A (en) * 1981-01-23 1988-06-21 Baxter Travenol Laboratories, Inc. Detection of serum antibody and surface antigen by radial partition immunoassay
US4786606A (en) * 1981-01-23 1988-11-22 Baxter Travenol Laboratories, Inc. Solid phase system for ligand assay
US4774174A (en) * 1981-01-23 1988-09-27 Baxter Travenol Laboratories, Inc. Solid phase system for ligand assay
US4442204A (en) * 1981-04-10 1984-04-10 Miles Laboratories, Inc. Homogeneous specific binding assay device and preformed complex method
US4447526A (en) * 1981-04-20 1984-05-08 Miles Laboratories, Inc. Homogeneous specific binding assay with carrier matrix incorporating specific binding partner
US5624814A (en) * 1981-08-20 1997-04-29 Becton Dickinson And Company Culture medium and method for culturing body fluids containing antibiotics
CA1209889A (en) * 1981-09-18 1986-08-19 Litai Weng Homogeneous assay on a non-porous surface
US4463090A (en) * 1981-09-30 1984-07-31 Harris Curtis C Cascade amplification enzyme immunoassay
US5073484A (en) * 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
US4654300A (en) * 1982-04-02 1987-03-31 Syntex (U.S.A.) Inc. Fluorescent microbead quenching assay
IL68506A (en) * 1982-05-04 1988-06-30 Syva Co Simultaneous calibration heterogeneous immunoassay method and device and kit for use therein
CA1228811A (en) 1983-05-05 1987-11-03 Robert G. Pergolizzi Assay method utilizing polynucleotide sequences
US4552839A (en) * 1983-08-01 1985-11-12 Syntex (U.S.A.) Inc. Determination of analytes in particle-containing medium
USRE34405E (en) * 1983-08-01 1993-10-12 Abbott Laboratories Determination of analytes in particle-containing medium
US4522786A (en) * 1983-08-10 1985-06-11 E. I. Du Pont De Nemours And Company Multilayered test device for detecting analytes in liquid test samples
DE3484505D1 (de) * 1983-12-19 1991-05-29 Daiichi Pure Chemicals Co Ltd Immuntest.
SE446229B (sv) * 1984-01-25 1986-08-18 Syn Tek Ab Sett och anordning for detektering av en analyt i ett prov som bringas att passera en yta till vilken bundits ett emne med specifik affinitet till analyten
US4791056A (en) * 1984-03-27 1988-12-13 Syntex (U.S.A.) Inc. Calibration device for heterogeneous immunoassay
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
US4624929A (en) * 1984-12-03 1986-11-25 Syntex (U.S.A.) Inc. Sample collector and assay device and method for its use
SE458643B (sv) * 1984-12-07 1989-04-17 Pharmacia Ab Anordning med kolonnelement uppdelat i provparti och referenspatri
DE3445816C1 (de) * 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
US5958790A (en) * 1984-12-20 1999-09-28 Nycomed Imaging As Solid phase transverse diffusion assay
DE3586951T2 (de) * 1984-12-20 1993-04-29 Nycomed Pharma As Festphasendiffusionstextverfahren.
US4740468A (en) * 1985-02-14 1988-04-26 Syntex (U.S.A.) Inc. Concentrating immunochemical test device and method
EP0216841A1 (de) * 1985-03-18 1987-04-08 Btg International Limited Antigenaktives protein und seine anwendung zur diagnose von gonorrhoea
US5879881A (en) * 1985-04-04 1999-03-09 Hybritech, Incorporated Solid phase system for use in ligand-receptor assays
US4824784A (en) * 1985-04-08 1989-04-25 Hygeia Sciences, Incorporated Chromogenic solution for immunoassay
US4623461A (en) * 1985-05-31 1986-11-18 Murex Corporation Transverse flow diagnostic device
US4670381A (en) * 1985-07-19 1987-06-02 Eastman Kodak Company Heterogeneous immunoassay utilizing horizontal separation in an analytical element
US4806311A (en) * 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone
US4900663A (en) * 1985-09-13 1990-02-13 Environmental Diagnostics, Inc. Test kit for determining the presence of organic materials and method of utilizing same
US5240844A (en) * 1985-09-13 1993-08-31 Wie Siong I Test kit for determining the presence of organic materials and method of utilizing same
US4675300A (en) * 1985-09-18 1987-06-23 The Board Of Trustees Of The Leland Stanford Junior University Laser-excitation fluorescence detection electrokinetic separation
TW203120B (de) * 1985-10-04 1993-04-01 Abbott Lab
US5501949A (en) * 1985-12-10 1996-03-26 Murex Diagnostics Corporation Particle bound binding component immunoassay
DE3543749A1 (de) * 1985-12-11 1987-06-19 Boehringer Mannheim Gmbh Verfahren zur herstellung eines reagenzpapieres fuer die immunologische analyse
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
JPS63501983A (ja) * 1985-12-12 1988-08-04 デニソン　マニユフアクチユアリング　カンパニ− 試験物質の測定
US5273877A (en) * 1985-12-24 1993-12-28 Massachusetts Institute Of Technology Non-histological cell type determination
US5160701A (en) * 1986-02-18 1992-11-03 Abbott Laboratories Solid-phase analytical device and method for using same
US4916056A (en) * 1986-02-18 1990-04-10 Abbott Laboratories Solid-phase analytical device and method for using same
JPS62231168A (ja) * 1986-03-21 1987-10-09 ハイブリテツク・インコ−ポレイテツド アナライト−レセプタ−分析用内部標準を設けるための改良法
US5190864A (en) * 1986-04-15 1993-03-02 Northeastern University Enzyme amplification by using free enzyme to release enzyme from an immobilized enzyme material
US4937188A (en) * 1986-04-15 1990-06-26 Northeastern University Enzyme activity amplification method for increasing assay sensitivity
US4851210A (en) * 1986-05-22 1989-07-25 Genelabs Incorporated Blood typing device
WO1987007384A1 (en) * 1986-05-30 1987-12-03 Quidel Enzyme immunoassay device
AU602694B2 (en) * 1986-06-09 1990-10-25 Ortho Diagnostic Systems Inc. Improved colloidal gold membrane assay
US4911794A (en) * 1986-06-20 1990-03-27 Molecular Devices Corporation Measuring with zero volume cell
US4915812A (en) * 1986-06-20 1990-04-10 Molecular Devices Corporation Zero volume cell
US5120504A (en) * 1986-07-14 1992-06-09 Hybritech Incorporated Apparatus for immunoassays with vent chennels in the container side wall
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US4790979A (en) * 1986-08-29 1988-12-13 Technimed Corporation Test strip and fixture
US5260193A (en) * 1986-09-05 1993-11-09 Syntex (U.S.A.) Inc. Immunoseparating strip
US4959307A (en) * 1986-09-05 1990-09-25 Syntex (U.S.A.) Inc. Immunoseparating strip
US5260194A (en) * 1986-09-05 1993-11-09 Syntex (U.S.A.) Inc. Immunoseparating strip
US5085988A (en) * 1986-09-05 1992-02-04 Syntex (U.S.A.) Inc. Immunoseparating strip
US4963468A (en) * 1986-09-05 1990-10-16 Syntex (U.S.A.) Inc. Immunoseparating strip
US5763262A (en) * 1986-09-18 1998-06-09 Quidel Corporation Immunodiagnostic device
US20010023075A1 (en) * 1992-04-03 2001-09-20 Siu-Yin Wong A immunodiagnositc device having a dessicant incorporated therein
EP0264804B1 (de) * 1986-10-23 1993-08-04 BEHRINGWERKE Aktiengesellschaft Bioaffine poröse Festphasen, ein Verfahren zur Herstellung von bioaffinen porösen Festphasen und ihre Verwendung
DE3636060C3 (de) * 1986-10-23 1994-04-07 Behringwerke Ag Bioaffine poröse Festphase, Verfahren zu deren Herstellung und ihre Verwendung
US5030558A (en) * 1986-11-07 1991-07-09 Syntex (U.S.A.) Inc. Qualitative immunochromatographic method and device
EP0271204A3 (de) * 1986-11-07 1989-10-25 Syntex (U.S.A.) Inc. Immunochromatographische Methode und Vorrichtung
JPH01501819A (ja) * 1986-11-13 1989-06-22 ジェネ　ラブス，インコーポレイティド 血液親和性診断方法
US4769333A (en) * 1987-01-05 1988-09-06 Dole Associates, Inc. Personal diagnostic kit
US4978502A (en) * 1987-01-05 1990-12-18 Dole Associates, Inc. Immunoassay or diagnostic device and method of manufacture
US4859603A (en) * 1987-01-05 1989-08-22 Dole Associates, Inc. Personal diagnostic kit
US5079142A (en) * 1987-01-23 1992-01-07 Synbiotics Corporation Orthogonal flow immunoassays and devices
US4920046A (en) * 1987-02-20 1990-04-24 Becton, Dickinson And Company Process, test device, and test kit for a rapid assay having a visible readout
US4833087A (en) * 1987-02-27 1989-05-23 Eastman Kodak Company Disposable container configured to produce uniform signal
US5250412A (en) * 1987-03-23 1993-10-05 Diamedix Corporation Swab device and method for collecting and analyzing a sample
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US4857453A (en) * 1987-04-07 1989-08-15 Syntex (U.S.A.) Inc. Immunoassay device
DE3856542T2 (de) 1987-04-27 2003-10-30 Inverness Medical Switzerland Testgerät zur Durchführung von spezifischen Bindungsprüfungen
US4973549A (en) * 1987-06-22 1990-11-27 Chemtrak Corporation Quantitative diagnostic assay employing signal producing agent bound to support and measuring migration distance of detectable signal
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
WO1989001626A1 (en) * 1987-08-19 1989-02-23 Flemming Gmbh Process and device for detecting an antigen or antibody in a liquid test specimen
US4981786A (en) * 1987-09-04 1991-01-01 Syntex (U.S.A.) Inc. Multiple port assay device
DE3730059A1 (de) * 1987-09-08 1989-03-30 Behringwerke Ag Verfahren zur bestimmung von "loeslichem" fibrin
EP0306772B1 (de) * 1987-09-11 1993-03-10 Abbott Laboratories Gerät für die laterale immunochromatographische Bestimmung
US4956302A (en) * 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
US5006464A (en) * 1987-10-01 1991-04-09 E-Y Laboratories, Inc. Directed flow diagnostic device and method
FR2621393B1 (fr) * 1987-10-05 1991-12-13 Toledano Jacques Dispositif de detection immunoenzymatique de substances a partir d'une goutte de sang ou de liquide provenant d'un quelconque milieu biologique
US4999163A (en) * 1987-10-29 1991-03-12 Hygeia Sciences, Inc. Disposable, pre-packaged device for conducting immunoassay procedures
US4943525A (en) * 1987-11-02 1990-07-24 Bioventures, Inc. Simultaneous immunoassay for the determination of antigens and antibodies
US5256372A (en) * 1987-11-06 1993-10-26 Idexx Corporation Dipstick test device including a removable filter assembly
US4818677A (en) * 1987-12-03 1989-04-04 Monoclonal Antibodies, Inc. Membrane assay using focused sample application
JPH0630628B2 (ja) * 1987-12-16 1994-04-27 キング醸造株式会社 生細胞数及び活力の測定方法
US5206177A (en) * 1988-01-21 1993-04-27 Boehringer Mannheim Corporation Apparatus for determining an analyte and method therefor
US4963325A (en) * 1988-05-06 1990-10-16 Hygeia Sciences, Inc. Swab expressor immunoassay device
US5137804A (en) * 1988-05-10 1992-08-11 E. I. Du Pont De Nemours And Company Assay device and immunoassay
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5039607A (en) * 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5334513A (en) * 1988-05-17 1994-08-02 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5164294A (en) * 1988-05-17 1992-11-17 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5573919A (en) * 1988-06-02 1996-11-12 Carter-Wallace Assay using an absorbent material
US5620845A (en) * 1988-06-06 1997-04-15 Ampcor, Inc. Immunoassay diagnostic kit
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US5059522A (en) * 1988-08-18 1991-10-22 Wayne Lawrence G Intrinsic enzyme dot blot immunoassay or indentification of microorganisms
US6306594B1 (en) 1988-11-14 2001-10-23 I-Stat Corporation Methods for microdispensing patterened layers
JPH04502961A (ja) * 1988-11-14 1992-05-28 アイデックス・ラボラトリーズ・インコーポレーテッド 二重吸収被分析物検出
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5028535A (en) * 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5939272A (en) * 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5252293A (en) * 1989-01-17 1993-10-12 Vladimir Drbal Analytical slide with porous filter membrane
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
DK0386644T3 (da) * 1989-03-10 1997-10-13 Hoffmann La Roche Reagenser til bestemmelse af lægemidler
US5106761A (en) * 1989-03-13 1992-04-21 International Canine Genetics, Inc. Method for detecting molecules in a liquid medium
US5340539A (en) * 1989-03-16 1994-08-23 Chemtrak, Inc. Non-instrumented cholesterol assay
EP0409176B1 (de) * 1989-07-17 1999-04-28 The Rockefeller University Verfahren und Mittel zum Nachweis von Krankheitszuständen aus Änderungen im Östrogenstoffwechsel
US5155049A (en) * 1989-08-22 1992-10-13 Terrapin Technologies, Inc. Blotting technique for membrane assay
US5185127A (en) * 1989-09-21 1993-02-09 Becton, Dickinson And Company Test device including flow control means
US5075078A (en) * 1989-10-05 1991-12-24 Abbott Laboratories Self-performing immunochromatographic device
US5376556A (en) * 1989-10-27 1994-12-27 Abbott Laboratories Surface-enhanced Raman spectroscopy immunoassay
US5147780A (en) * 1989-12-01 1992-09-15 Sangstat Medical Corporation Multiwell stat test
US5646046A (en) * 1989-12-01 1997-07-08 Akzo Nobel N.V. Method and instrument for automatically performing analysis relating to thrombosis and hemostasis
US5252496A (en) 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
JP3070764B2 (ja) * 1990-03-12 2000-07-31 バイオサイト・ダイアグノスティックス・インコーポレイテッド 生物学的検定装置及びそれを用いた検定方法
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
US5559032A (en) * 1990-06-29 1996-09-24 Pomeroy; Patrick C. Method and apparatus for post-transfer assaying of material on solid support
US5158869A (en) * 1990-07-06 1992-10-27 Sangstat Medical Corporation Analyte determination using comparison of juxtaposed competitive and non-competitive elisa results and device therefore
US5143852A (en) 1990-09-14 1992-09-01 Biosite Diagnostics, Inc. Antibodies to ligand analogues and their utility in ligand-receptor assays
CA2072758A1 (en) * 1990-09-14 1992-03-15 Kenneth Francis Buechler Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
WO1992005440A1 (en) * 1990-09-26 1992-04-02 Akers Research Corporation Improved ligand assay
US5231035A (en) * 1991-01-11 1993-07-27 Akers Research Corporation Latex agglutination assay
US5607863A (en) * 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5468648A (en) * 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
US5869345A (en) * 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5264589A (en) * 1991-06-06 1993-11-23 Miles Inc. Merocyanine protein error indicators
DE4121493A1 (de) * 1991-06-28 1993-01-07 Draegerwerk Ag Analysevorrichtung zur quantitativen, immunologischen bestimmung von schadstoffen
US5451504A (en) * 1991-07-29 1995-09-19 Serex, Inc. Method and device for detecting the presence of analyte in a sample
US5726010A (en) * 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US6007999A (en) * 1991-07-31 1999-12-28 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
EP0610356B1 (de) * 1991-10-18 2001-01-31 SYNSORB Biotech Inc. Behandlung bakterieller dysenterie
WO1993015230A1 (en) * 1992-01-22 1993-08-05 Abbott Laboratories Calibration reagents for semi-quantitative binding assays and devices
WO1993018398A1 (en) * 1992-03-10 1993-09-16 Quidel Corporation Red blood cell separation means for specific binding assays
WO1993021530A1 (de) * 1992-04-10 1993-10-28 Messerschmitt-Bölkow-Blohm Gmbh Verfahren und vorrichtung zur empfindlichkeits- und selektivitätssteigerung bei immuno-assays, molekül-rezeptor-, dna-komplementär-dna- und gast-wirtsmolekül-wechselwirkungs-assays
US5395754A (en) * 1992-07-31 1995-03-07 Hybritech Incorporated Membrane-based immunoassay method
US5447838A (en) * 1992-08-05 1995-09-05 Hybritech Incorporated Protein-dye conjugate for confirmation of correct dilution of calibrators
EP0583980A1 (de) * 1992-08-20 1994-02-23 Eli Lilly And Company Verfahren zur Herstellung von monoklonalen Antikörpern aus Kaninchen
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
AU670108B2 (en) 1992-09-11 1996-07-04 Becton Dickinson & Company Improved antibodies to plasmodium falciparum
FI92882C (fi) * 1992-12-29 1995-01-10 Medix Biochemica Ab Oy Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi
US5344754A (en) * 1993-01-13 1994-09-06 Avocet Medical, Inc. Assay timed by electrical resistance change and test strip
US5500375A (en) * 1993-04-13 1996-03-19 Serex, Inc. Integrated packaging-holder device for immunochromatographic assays in flow-through or dipstick formats
US6562333B1 (en) 1993-06-14 2003-05-13 Schering Corporation Purified mammalian CTLA-8 antigens and related reagents
US5684144A (en) * 1993-07-28 1997-11-04 University Of North Texas Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof
US5837546A (en) * 1993-08-24 1998-11-17 Metrika, Inc. Electronic assay device and method
US5770389A (en) * 1993-09-27 1998-06-23 Abbott Laboratories Apparatus and method for determining the quanity of an analyte in a biological sample by means of transmission photometry
US5695928A (en) 1993-12-10 1997-12-09 Novartis Corporation Rapid immunoassay for detection of antibodies or antigens incorporating simultaneous sample extraction and immunogenic reaction
US5561045A (en) * 1994-01-04 1996-10-01 Intracel Corporation Detection reagent, article, and immunoassay method
US5547833A (en) * 1994-01-04 1996-08-20 Intracel Corporation Radial flow assay, delivering member, test kit, and methods
US6335160B1 (en) * 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
US5550032A (en) * 1994-05-27 1996-08-27 George Mason University Biological assay for microbial contamination
DK0705902T3 (da) 1994-08-12 2002-03-11 Univ Utah Res Found 17q-koblet bryst- og ovariecancerprædisponeringsgen
CA2196797C (en) 1994-08-12 2000-10-10 Donna M. Shattuck-Eidens In vivo mutations and polymorphisms in the 17q-linked breast and ovarian cancer susceptibility gene
US8236493B2 (en) 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6974666B1 (en) * 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
JP3010699U (ja) * 1994-10-29 1995-05-02 株式会社ニッポンジーン 直接採尿の可能なクロマト式検査装置
US5633149A (en) 1994-12-07 1997-05-27 Incyte Pharmaceuticals, Inc. Polynucleotide encoding novel chemokine expressed in inflamed adenoid
US7005509B1 (en) 1995-02-17 2006-02-28 Incyte Corporation Chemokine PANEC-1 polynucleotides and compositions and methods related thereto
US5712172A (en) 1995-05-18 1998-01-27 Wyntek Diagnostics, Inc. One step immunochromatographic device and method of use
US5739041A (en) * 1995-05-02 1998-04-14 Carter Wallace, Inc. Diagnostic detection device
US6319676B1 (en) 1995-05-02 2001-11-20 Carter Wallace, Inc. Diagnostic detection device and method
GB0112226D0 (en) * 2001-05-18 2001-07-11 Danisco Method of improving dough and bread quality
CA2245835A1 (en) 1995-06-14 1997-01-03 The Regents Of The University Of California Novel high affinity human antibodies to tumor antigens
AU6720096A (en) 1995-08-09 1997-03-05 Quidel Corporation Test strip and method for one step lateral flow assay
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
US7455964B1 (en) 1996-07-15 2008-11-25 The Hospital For Sick Children Genes from the 20q13 amplicon and their uses
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
DE69625678T3 (de) 1995-12-18 2006-11-09 The University Of Utah Research Foundation, Salt Lake City Chromosom 13 verbundene Brustkrebsempfindlichkeitsgen BRCA2
US20010018514A1 (en) * 1998-07-31 2001-08-30 Mcgall Glenn H. Nucleic acid labeling compounds
US7291463B2 (en) * 1996-01-23 2007-11-06 Affymetrix, Inc. Nucleic acid labeling compounds
US6965020B2 (en) 1996-01-23 2005-11-15 Affymetrix, Inc. Nucleic acid labeling compounds
US7282327B2 (en) * 1996-01-23 2007-10-16 Affymetrix, Inc. Nucleic acid labeling compounds
US7423143B2 (en) * 1996-01-23 2008-09-09 Affymetrix. Inc. Nucleic acid labeling compounds
US6864059B2 (en) * 1996-01-23 2005-03-08 Affymetrix, Inc. Biotin containing C-glycoside nucleic acid labeling compounds
EP0880598A4 (de) 1996-01-23 2005-02-23 Affymetrix Inc Verfahren zur analyse von nukleinsäure
US20040210045A1 (en) * 1996-01-23 2004-10-21 Mcgall Glenn Nucleic acid labeling compounds
US5851777A (en) * 1996-02-05 1998-12-22 Dade Behring Inc. Homogeneous sol-sol assay
US6924094B1 (en) 1996-02-08 2005-08-02 Affymetrix, Inc. Chip-based species identification and phenotypic characterization of microorganisms
EP1728875A3 (de) 1996-02-08 2007-05-09 Affymetrix, Inc. Speziesbestimmung und phenotypische Charakterisierung von Mikroorganismen auf der Basis eines Chips
WO1997029212A1 (en) 1996-02-08 1997-08-14 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
US5741647A (en) * 1996-02-16 1998-04-21 Tam; Joseph Wing On Flow through nucleic acid hybridisation uses thereof and a device thereof
US5882644A (en) * 1996-03-22 1999-03-16 Protein Design Labs, Inc. Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof
AU742668B2 (en) * 1996-03-22 2002-01-10 Morehouse School Of Medicine Immunogenic compositions comprising porphyromonas gingivalis peptides and methods
US5968839A (en) * 1996-05-13 1999-10-19 Metrika, Inc. Method and device producing a predetermined distribution of detectable change in assays
DK0912738T3 (da) * 1996-05-22 2008-11-17 Viventia Biotech Inc Antigen-bindende-fragmenter der specifikt detekterer cancerceller, nukleotider der koder fragmenterne og anvendelse deraf til profylakse og detektion af cancere
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
US20050214827A1 (en) * 1996-07-08 2005-09-29 Burstein Technologies, Inc. Assay device and method
EP1947183B1 (de) 1996-08-16 2013-07-17 Merck Sharp & Dohme Corp. Säugerzelloberflächenantigene und damit zusammenhängende Reagenzien
US5945345A (en) * 1996-08-27 1999-08-31 Metrika, Inc. Device for preventing assay interference using silver or lead to remove the interferant
DK0932678T4 (da) * 1996-09-24 2010-07-12 Genentech Inc En familie af gener kodende for apoptoserelaterede peptider, peptider kodet deraf og fremgangsmåder til anvendelse deraf
US20070299005A1 (en) * 1996-09-24 2007-12-27 Tanox, Inc. Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
US5998221A (en) * 1996-09-25 1999-12-07 Becton, Dickinson And Company Non-instrumented assay with quantitative and qualitative results
DE69723531T3 (de) 1996-10-01 2012-09-06 Geron Corp. Katalytische Untereinheit der menschlichen Telomerase
US6475789B1 (en) * 1996-10-01 2002-11-05 University Technology Corporation Human telomerase catalytic subunit: diagnostic and therapeutic methods
US7585622B1 (en) 1996-10-01 2009-09-08 Geron Corporation Increasing the proliferative capacity of cells using telomerase reverse transcriptase
US6093809A (en) 1996-10-01 2000-07-25 University Technology Corporation Telomerase
US6261836B1 (en) 1996-10-01 2001-07-17 Geron Corporation Telomerase
US6808880B2 (en) * 1996-10-01 2004-10-26 Geron Corporation Method for detecting polynucleotides encoding telomerase
US6610839B1 (en) * 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
US5710005A (en) * 1996-10-29 1998-01-20 Biocode, Inc. Analyte detection with a gradient lateral flow device
EP1114864B9 (de) 1996-12-13 2013-05-08 Schering Corporation Oberflächenantigene aus Säugern
US5879951A (en) * 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
EP2172478A3 (de) 1997-02-07 2010-07-28 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Aktivitätsabhängiger neurotrophischer Faktor III (ADNF III)
CA2286910A1 (en) 1997-03-05 1998-09-11 Raouf A. Guirguis Fluid specimen collecting and testing apparatus
US7622549B2 (en) * 1997-04-18 2009-11-24 Geron Corporation Human telomerase reverse transcriptase polypeptides
US7413864B2 (en) * 1997-04-18 2008-08-19 Geron Corporation Treating cancer using a telomerase vaccine
US20050013825A1 (en) * 1997-04-18 2005-01-20 Geron Corporation Vaccine containing the catalytic subunit of telomerase for treating cancer
US6103536A (en) 1997-05-02 2000-08-15 Silver Lake Research Corporation Internally referenced competitive assays
AU740333B2 (en) 1997-05-07 2001-11-01 Schering Corporation Human receptor proteins; related reagents and methods
US5939252A (en) * 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US7115722B1 (en) 1997-05-22 2006-10-03 Viventia Biotech, Inc. Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US6258548B1 (en) 1997-06-05 2001-07-10 A-Fem Medical Corporation Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules
US20020122807A1 (en) * 1998-07-07 2002-09-05 Dan Michael D. Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
AR014891A1 (es) 1997-07-09 2001-04-11 Schering Corp Genes aislados de proteinas de membranas de mamiferos; reactivos relacionados
US6228638B1 (en) 1997-07-11 2001-05-08 University Of North Texas, Health Science Center At Fort Worth Escherichia coli CSRB gene and RNA encoded thereby
US20030157642A1 (en) * 1997-07-15 2003-08-21 Caldwell Robert M. Increasing production of proteins in gram-positive microorganisms
US6506579B1 (en) 1997-07-15 2003-01-14 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms using SecG
US6762039B2 (en) * 1997-07-15 2004-07-13 Genencor International, Inc. Bacillus subtillis with an inactivated cysteine protease-1
US6723550B1 (en) * 1997-07-15 2004-04-20 Genencor International, Inc. Proteases from gram-positive organisms
US6521421B1 (en) * 1997-07-16 2003-02-18 Genencor International, Inc. Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same
PE20000183A1 (es) 1997-07-25 2000-03-11 Schering Corp Citoquinas de mamiferos y reactivos relacionados
US6180411B1 (en) 1997-08-01 2001-01-30 The Regents Of The University Of California Light-triggered indicators that memorize analyte concentrations
PT1003861E (pt) 1997-08-01 2007-01-31 Schering Corp Proteínas de membrana de células de mamíferos;reagentes relacionados
US6960457B1 (en) 1997-09-04 2005-11-01 Stanford University Reversible immobilization of arginine-tagged moieties on a silicate surface
US7252950B1 (en) 1997-09-04 2007-08-07 The Regents Of The University Of California Assays for detecting modulators of cytoskeletal function
US6300117B1 (en) * 1997-09-15 2001-10-09 Genencor International, Inc. Proteases from gram-positive organisms
US6521440B1 (en) * 1997-09-15 2003-02-18 Genencor International, Inc. Proteases from gram-positive organisms
US7378244B2 (en) * 1997-10-01 2008-05-27 Geron Corporation Telomerase promoters sequences for screening telomerase modulators
US6316241B1 (en) * 1997-11-20 2001-11-13 Genencor International, Inc. Alpha/beta hydrolase-fold enzymes
GB9724629D0 (en) * 1997-11-20 1998-01-21 Genencor Int Bv Alpha/beta hydrolase-fold enzymes
GB9724627D0 (en) 1997-11-20 1998-01-21 Genencor Int Bv Gram positive microorganism formate pathway
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
US6465186B1 (en) * 1997-12-30 2002-10-15 Genecor International, Inc. Proteases from gram positive organisms
GB9727470D0 (en) * 1997-12-30 1998-02-25 Genencor Int Bv Proteases from gram positive organisms
US6599731B1 (en) 1997-12-30 2003-07-29 Genencor International, Inc. Proteases from gram positive organisms
US6528255B1 (en) * 1997-12-30 2003-03-04 Genencor International, Inc. Proteases from gram positive organisms
US6780609B1 (en) 1998-10-23 2004-08-24 Genome Therapeutics Corporation High bone mass gene of 1.1q13.3
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
US6673914B1 (en) 1998-01-22 2004-01-06 John Wayne Cancer Institute Human tumor-associated gene
US6764830B1 (en) 1998-01-23 2004-07-20 The Regents Of The University Of California Thermomyces lanuginosus kinesin motor protein and methods of screening for modulators of kinesin proteins
US6267722B1 (en) 1998-02-03 2001-07-31 Adeza Biomedical Corporation Point of care diagnostic systems
US6394952B1 (en) 1998-02-03 2002-05-28 Adeza Biomedical Corporation Point of care diagnostic systems
US6596501B2 (en) 1998-02-23 2003-07-22 Fred Hutchinson Cancer Research Center Method of diagnosing autoimmune disease
WO1999045124A2 (en) 1998-03-04 1999-09-10 Genencor International, Inc. Modified forms of pullulanase
US6284194B1 (en) 1998-03-11 2001-09-04 Albert E. Chu Analytical assay device and methods using surfactant treated membranes to increase assay sensitivity
WO1999047934A2 (en) 1998-03-20 1999-09-23 The Curators Of The University Of Missouri Early pregnancy diagnosis using pags (pregnancy-associated glycoproteins)
US8062908B2 (en) * 1999-03-29 2011-11-22 Orasure Technologies, Inc. Device for collection and assay of oral fluids
EP1086372B1 (de) 1998-03-30 2006-05-31 OraSure Technologies, Inc. Sammelapparat für einschrittigen test von mundflüssigkeiten
US6303081B1 (en) 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
AU3217599A (en) * 1998-03-31 1999-10-18 Genzyme Corporation Methods for the diagnosis and treatment of lung cancer
US6337200B1 (en) * 1998-03-31 2002-01-08 Geron Corporation Human telomerase catalytic subunit variants
US6274314B1 (en) 1998-04-02 2001-08-14 Nyxis Neurotherapies, Inc. Diagnostic assay for the modified nucleosides pseudouridine, 7-methyladenosine, or 1-methyladenosine
US7108968B2 (en) * 1998-04-03 2006-09-19 Affymetrix, Inc. Mycobacterial rpoB sequences
US6699969B1 (en) 1998-04-14 2004-03-02 The Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
WO1999053295A1 (en) 1998-04-14 1999-10-21 The Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6872537B1 (en) 1998-04-14 2005-03-29 Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6348573B1 (en) 1998-04-27 2002-02-19 The Regents Of The University Of Michigan Compositions and methods for identifying apoptosis signaling pathway inhibitors and activators
US6271044B1 (en) 1998-05-06 2001-08-07 University Of Pittsburgh Of The Commonwealth System Of Higher Education Method and kit for detecting an analyte
ES2188190T5 (es) 1998-07-21 2007-11-16 Danisco A/S Producto alimentario.
WO2000005582A2 (en) * 1998-07-21 2000-02-03 Burstein Laboratories, Inc. Optical disc-based assay devices and methods
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
EP1806362B1 (de) 1998-07-28 2010-07-21 The Regents of the University of California Nukleinsäuren, die für einen an ein G-Protein gekoppelten, an der sensorischen Transduktion beteiligten Rezeptor kodieren
SE9803099D0 (sv) 1998-09-13 1998-09-13 Karolinska Innovations Ab Nucleic acid transfer
EP1115867A1 (de) 1998-09-21 2001-07-18 Schering Corporation Menschliche interleukin-b50. therapeutische verwendungen
EP0997476A3 (de) 1998-09-25 2000-07-19 Schering-Plough Antikörper gegen ein Antigen auf Langerhans Zellen in Säugetieren und deren Verwendungen
JP3622532B2 (ja) * 1998-10-13 2005-02-23 松下電器産業株式会社 酵素免疫分析用試薬及びそれを用いた分析方法
US7071324B2 (en) * 1998-10-13 2006-07-04 Brown University Research Foundation Systems and methods for sequencing by hybridization
EP1123401A1 (de) 1998-10-22 2001-08-16 The General Hospital Corporation Bioaktive peptide und peptid-derivate von parathyroidhormon (pth) und parathyroidhormon verwandte peptide (pthrp)
US7297554B2 (en) * 1998-11-18 2007-11-20 Microdiagnostics, Inc. Immunoassay system
US6638760B1 (en) 1998-11-25 2003-10-28 Pe Corporation (Ny) Method and apparatus for flow-through hybridization
JP2002534122A (ja) 1999-01-11 2002-10-15 シェーリング コーポレイション インターロイキン−１７関連哺乳動物サイトカイン、それをコードするポリヌクレオチド、使用
EP1159611A1 (de) * 1999-01-15 2001-12-05 Medtox Scientific Inc. Querflussteststreifen
US6156515A (en) * 1999-02-09 2000-12-05 Urocor, Inc. Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
JP2003500010A (ja) 1999-03-11 2003-01-07 シェリング・コーポレーション 哺乳動物サイトカイン；関連試薬および方法
AU4057300A (en) 1999-03-30 2000-10-16 Board Of Regents, The University Of Texas System Compositions and methods for modifying toxic effects of proteinacious compounds
KR20110102476A (ko) 1999-05-13 2011-09-16 메디칼 리서취 카운실 Ｏｘ2 수용체 동족체
AU5011400A (en) 1999-05-14 2000-12-05 Arbor Vita Corporation Molecular interactions in t cells
EP2258849A1 (de) 1999-06-01 2010-12-08 Schering Corporation Säugetier-Rezeptorproteine; ähnliche Reagentien und Methoden
GB9914210D0 (en) 1999-06-17 1999-08-18 Danisco Promoter
WO2001009176A2 (en) 1999-07-30 2001-02-08 Schering Corporation Mammalian cytokines; related reagents
EP1905832A3 (de) 1999-09-09 2009-09-09 Schering Corporation Säuger Interleukin-12 P40 und Interleukin B30, Antikörper, Verwendungen in pharmazeutischen Zusammenstellungen
WO2001023521A2 (en) * 1999-09-29 2001-04-05 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
US6306665B1 (en) 1999-10-13 2001-10-23 A-Fem Medical Corporation Covalent bonding of molecules to an activated solid phase material
US7332275B2 (en) 1999-10-13 2008-02-19 Sequenom, Inc. Methods for detecting methylated nucleotides
WO2001029079A1 (en) 1999-10-18 2001-04-26 Prince Henry's Institute Of Medical Research IMMUNO-INTERACTIVE FRAGMENTS OF THE αC SUBUNIT OF INHIBIN
US7030228B1 (en) 1999-11-15 2006-04-18 Miltenyi Biotec Gmbh Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
US6458326B1 (en) 1999-11-24 2002-10-01 Home Diagnostics, Inc. Protective test strip platform
EP1232185A2 (de) 1999-11-24 2002-08-21 Schering Corporation Verfahren zur inhibierung von krebs-metastasen
EP2336775A3 (de) 1999-12-06 2013-03-20 Board Of Trustees Of The University Of Illinois Hochaffine TCR-Proteine und Verfahren
FR2802214B1 (fr) * 1999-12-09 2005-07-22 Biomerieux Sa Nouveaux substrats chromogenes a base d'alizarine, leurs utilisations et compositions contenant de tels substrats
US6544792B1 (en) * 1999-12-21 2003-04-08 Genencor International, Inc. Production of secreted polypeptides
WO2001055182A1 (en) 2000-01-25 2001-08-02 The University Of Queensland PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA
DE10003734A1 (de) * 2000-01-28 2001-08-02 Bosch Gmbh Robert Detektionsverfahren und -vorrichtung
US20010051348A1 (en) * 2000-01-28 2001-12-13 Lee Chee Wee Novel ligands and methods for preparing same
EP1254369B1 (de) 2000-02-08 2010-10-06 Sangamo BioSciences, Inc. Zellen zur entdeckung von medikamenten
US6792791B2 (en) * 2000-02-18 2004-09-21 Matsushita Electric Industrial Co., Ltd. Inspection chip for sensor measuring instrument
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
JP2003527584A (ja) * 2000-03-09 2003-09-16 ヘスカ コーポレイション 動物の免疫状態を決定するための組換え抗原の使用
US7829313B2 (en) * 2000-03-24 2010-11-09 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US7875442B2 (en) * 2000-03-24 2011-01-25 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US8288128B2 (en) * 2004-11-18 2012-10-16 Eppendorf Array Technologies S.A. Real-time quantification of multiple targets on a micro-array
US20030108927A1 (en) * 2000-04-03 2003-06-12 Kathryn Leishman Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
DE60136921D1 (de) 2000-04-18 2009-01-22 Schering Corp Medizinische Verwendung von IL-174 Agonisten und Antagonisten
CA2407715C (en) 2000-04-29 2009-03-24 University Of Iowa Research Foundation Diagnostics and therapeutics for macular degeneration-related disorders
PT1287130E (pt) 2000-05-10 2008-09-01 Schering Corp Proteínas de subunidades de receptores de citocinas de mamífero, métodos e reagentes relacionados
US7422743B2 (en) 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
AUPQ755300A0 (en) 2000-05-17 2000-06-08 Monash University Immune potentiating compositions
EP1433792A3 (de) 2000-05-25 2004-11-17 Schering Corporation Menschlische-rezeptor Proteine; verwandte Reagenzien und Methoden
WO2005000087A2 (en) * 2003-06-03 2005-01-06 Chiron Corporation Gene products differentially expressed in cancerous colon cells and their methods of use ii
US6528321B1 (en) 2000-06-26 2003-03-04 Beckman Coulter, Inc. Opposable-element chromatographic assay device for detection of analytes in whole blood samples
US6673614B2 (en) 2000-06-27 2004-01-06 Cell Genesys, Inc. Rapid methods and kits for detection and semi-quantitation of anti-adenovirus antibody
US6958214B2 (en) * 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
US6372516B1 (en) 2000-09-07 2002-04-16 Sun Biomedical Laboratories, Inc. Lateral flow test device
DE60142840D1 (de) 2000-09-08 2010-09-30 Univ Texas Durch phagendisplay identifizierte zielpeptide des menschen und der maus
ATE549347T1 (de) 2000-09-08 2012-03-15 Schering Corp Gene von säugetiere, und damit verbundene reagentien, methoden
US6673623B1 (en) 2000-09-12 2004-01-06 Novocure, Inc. Methods and compositions that control lipid production
AU2001292749A1 (en) * 2000-09-18 2002-03-26 Genencor International, Inc. Twin-arginine translocation in bacillus
US7186521B2 (en) * 2000-09-25 2007-03-06 The Regents Of The University Of California Determining the effect of a substance on sequestration, uptake, and accumulation of amyloid in brain cells
US7052831B2 (en) * 2000-09-29 2006-05-30 Becton Dickinson And Company Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device
US7045283B2 (en) 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
AU2002252773A1 (en) * 2000-11-29 2002-06-11 Lynkeus Boitech Gmbh Retina-specific human proteins c70rf9, c120rf7, mpp4 and f379
US20020165149A1 (en) * 2000-12-08 2002-11-07 Kranz David M. Mutated class II major histocompatibility proteins
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
GB0101762D0 (en) * 2001-01-23 2001-03-07 Medical Res Council Method
US7087389B2 (en) 2001-02-09 2006-08-08 Council Of Scientific & Industrial Research Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity
US20020168663A1 (en) * 2001-02-27 2002-11-14 Phan Brigitte Chau Methods for DNA conjugation onto solid phase including related optical biodiscs and disc drive systems
US6525330B2 (en) 2001-02-28 2003-02-25 Home Diagnostics, Inc. Method of strip insertion detection
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
US6562625B2 (en) 2001-02-28 2003-05-13 Home Diagnostics, Inc. Distinguishing test types through spectral analysis
CA2440615A1 (en) 2001-03-12 2002-09-19 Affymetrix, Inc. Nucleic acid labeling compounds
US20030104410A1 (en) * 2001-03-16 2003-06-05 Affymetrix, Inc. Human microarray
US20030228639A1 (en) * 2001-03-19 2003-12-11 Wright George L Prostate cancer markers
US20030220475A1 (en) * 2001-04-03 2003-11-27 Fields Howard A. Neutralizing immunogenic hev polypepetides
US7618789B2 (en) * 2001-04-06 2009-11-17 The United States Of America As Represented By The Secretary Of Department Of Health And Human Services Use of semenogelin in the diagnosis, prognosis and treatment of cancer
US7867756B2 (en) * 2001-04-12 2011-01-11 Arkray, Inc. Specimen analyzing implement
US6916626B1 (en) * 2001-04-25 2005-07-12 Rockeby Biomed Ltd. Detection of Candida
AU2002339115B2 (en) 2001-05-18 2007-03-15 Dupont Nutrition Biosciences Aps Method of preparing a dough with an enzyme
WO2002094985A2 (en) 2001-05-22 2002-11-28 Merck & Co., Inc. Beta-secretase substrates and uses thereof
AU2002312410A1 (en) * 2001-06-08 2002-12-23 Target Protein Technologies, Inc. Tissue-specific endothelial membrane proteins
US20070190534A1 (en) * 2001-06-11 2007-08-16 Genesis Genomics Inc. Mitochondrial sites and genes associated with prostate cancer
AU2002326315B2 (en) 2001-06-26 2007-07-05 Senomyx, Inc. T1R hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7141416B2 (en) * 2001-07-12 2006-11-28 Burstein Technologies, Inc. Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith
CA2454275C (en) * 2001-07-23 2012-10-23 The General Hospital Corporation Conformationally constrained parathyroid hormone (pth) analogs
US7300633B2 (en) 2001-07-25 2007-11-27 Oakville Hong Kong Company Limited Specimen collection container
US7270959B2 (en) 2001-07-25 2007-09-18 Oakville Hong Kong Company Limited Specimen collection container
JP4265149B2 (ja) * 2001-07-25 2009-05-20 セイコーエプソン株式会社 電気光学装置、電気光学装置の製造方法
US6833441B2 (en) 2001-08-01 2004-12-21 Abmaxis, Inc. Compositions and methods for generating chimeric heteromultimers
DE60237696D1 (de) * 2001-08-01 2010-10-28 Univ Utah Am n-terminus trunkierte isoformen von zyklischen phosphodiesterasen pde3a
US20030082596A1 (en) * 2001-08-08 2003-05-01 Michael Mittmann Methods of genetic analysis of probes: test3
US6855561B2 (en) * 2001-09-10 2005-02-15 Quidel Corporation Method for adding an apparent non-signal line to a lateral flow assay
EP1438583B1 (de) 2001-09-20 2009-09-16 Board of Regents, The University of Texas System Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper-komplexe mit elisa-tests
US7108975B2 (en) * 2001-09-21 2006-09-19 Regents Of The University Of Michigan Atlastin
US7582425B2 (en) * 2001-09-21 2009-09-01 The Regents Of The University Of Michigan Atlastin
EP1437936A4 (de) 2001-09-27 2005-10-12 Pioneer Hi Bred Int Phytat-polynukleotide und verfahren zu ihrer verwendung
AU2002330102A1 (en) * 2001-09-28 2003-04-14 Aspenbio, Inc. Bovine pregnancy test
AU2002334997A1 (en) 2001-10-12 2003-04-22 Schering Corporation Use of bispecific antibodies to regulate immune responses
US7537731B2 (en) * 2001-10-19 2009-05-26 Panasonic Corporation Specific binding analysis device
US7175983B2 (en) * 2001-11-02 2007-02-13 Abmaxis, Inc. Adapter-directed display systems
AU2002366097B2 (en) 2001-11-20 2008-09-18 Monsanto Technology Llc Compositions and methods for accurate early pregnancy diagnosis
US6952704B2 (en) * 2001-11-26 2005-10-04 Microsoft Corporation Extending a directory schema independent of schema modification
US20030099621A1 (en) 2001-11-29 2003-05-29 Robert Chow Stem cell screening and transplantation therapy for HIV infection
ATE554790T1 (de) * 2001-12-07 2012-05-15 Univ Wyoming Verfahren und zusammensetzungen zur diagnose von asthma
CA2469935C (en) * 2001-12-12 2014-02-11 Proteome Systems Intellectual Property Pty Ltd. Diagnostic testing process
US7244393B2 (en) 2001-12-21 2007-07-17 Kimberly-Clark Worldwide, Inc. Diagnostic device and system
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US8367013B2 (en) 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US6837171B1 (en) 2002-04-29 2005-01-04 Palmer/Snyder Furniture Company Lightweight table with unitized table top
US20050003459A1 (en) * 2002-01-30 2005-01-06 Krutzik Siegfried Richard Multi-purpose optical analysis disc for conducting assays and related methods for attaching capture agents
US7255986B2 (en) * 2002-01-31 2007-08-14 The Board Of Trustees Operating Michigan State University Compositions for the diagnosis and treatment of epizootic catarrhal enteritis in ferrets
EP2077277A1 (de) 2002-02-01 2009-07-08 Schering Corporation "Verwendung von Säuger-Zytokin; verwandte Reagenzien"
US7094579B2 (en) 2002-02-13 2006-08-22 Xoma Technology Ltd. Eukaryotic signal sequences for prokaryotic expression
WO2003072710A2 (en) * 2002-02-21 2003-09-04 Eastern Virginia Medical School Protein biomarkers that distinguish prostate cancer from non-malignant cells
US7053188B2 (en) 2002-02-22 2006-05-30 Purdue Research Foundation Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
WO2003072799A2 (en) 2002-02-22 2003-09-04 The Government Of The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Brother of the regulator of imprinted sites (boris)
US6703216B2 (en) 2002-03-14 2004-03-09 The Regents Of The University Of California Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB)
JP2004003976A (ja) * 2002-04-05 2004-01-08 Matsushita Electric Ind Co Ltd 特異結合分析方法およびこれに用いるデバイス
US7332585B2 (en) 2002-04-05 2008-02-19 The Regents Of The California University Bispecific single chain Fv antibody molecules and methods of use thereof
US7534580B2 (en) * 2002-05-01 2009-05-19 Ambrilia Biopharma Inc. PSP94 diagnostic reagents and assays
CA2391438A1 (en) * 2002-05-01 2003-11-01 Procyon Biopharma Inc. Psp94 diagnostic reagents and assays
US7842513B2 (en) * 2002-05-02 2010-11-30 Aspenbio Pharma, Inc. Pregnancy detection
EP1501863A4 (de) * 2002-05-03 2007-01-24 Sequenom Inc Kinaseankerproteinmuteine, peptide davon und damit im zusammenhang stehende verfahren
WO2003102595A1 (en) * 2002-05-31 2003-12-11 Genetype Pty Ltd Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood
CA2490261A1 (en) 2002-06-27 2004-01-08 The University Of Queensland Differentiation modulating agents and uses therefor
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
US20040175378A1 (en) 2002-07-15 2004-09-09 Board Of Regents, The University Of Texas System Selected antibody compositions and methods for binding to aminophospholipids
US6916474B2 (en) 2002-07-15 2005-07-12 Board Of Regents, The University Of Texas System Antibodies with increased affinities for anthrax antigens
US7794716B2 (en) 2002-07-25 2010-09-14 Glenveigh Pharmaceuticals, Llc Antibody composition and passive immunization against pregnancy-induced hypertension
DK1545599T3 (en) 2002-07-26 2015-08-03 Inst Medical W & E Hall IMMUNOGENIC PREPARATIONS AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS THEREOF
AU2003304411A1 (en) 2002-08-01 2005-03-07 The Regents Of The University Of California Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
EA200500330A1 (ru) * 2002-08-10 2006-06-30 Йейл Юниверсити Антагонисты nogo рецепторов
CA2533915C (en) 2002-08-13 2020-09-22 N-Dia, Inc. Devices and methods for detecting amniotic fluid in vaginal secretions
ES2311751T3 (es) 2002-08-23 2009-02-16 Bayer Healthcare Ag Biomarcadores de polipeptidos para la diagnosis de la enfermedad de alzheimer.
US7314763B2 (en) 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7432105B2 (en) 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
BR0314155A (pt) 2002-09-09 2005-07-05 Arbor Vita Corp Métodos para diagnosticar câncer cervical
US6774758B2 (en) * 2002-09-11 2004-08-10 Kalyan P. Gokhale Low harmonic rectifier circuit
US20050042621A1 (en) * 2002-09-27 2005-02-24 Affymetrix, Inc. Method for preparing a nucleic acid sample for hybridization to an array
WO2004033101A1 (en) * 2002-10-11 2004-04-22 Zbx Corporation Diagnostic devices
JP2006514614A (ja) 2002-10-24 2006-05-11 ステリックス リミテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型および２型のインヒビター
EP1565745A4 (de) * 2002-11-12 2007-06-27 Strategic Diagnostics Inc Isolation und bestätigung von analyten aus testeinrichtungen
US7250289B2 (en) * 2002-11-20 2007-07-31 Affymetrix, Inc. Methods of genetic analysis of mouse
US7314750B2 (en) * 2002-11-20 2008-01-01 Affymetrix, Inc. Addressable oligonucleotide array of the rat genome
US7781172B2 (en) 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
AU2003298706A1 (en) 2002-12-04 2004-06-23 Applera Corporation Multiplex amplification of polynucleotides
US20040121334A1 (en) 2002-12-19 2004-06-24 Kimberly-Clark Worldwide, Inc. Self-calibrated flow-through assay devices
US7247500B2 (en) 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
WO2004059280A2 (en) * 2002-12-26 2004-07-15 Meso Scale Technologies, Llc Methods, compositions and kits for biomarker extraction
WO2004058938A2 (en) * 2002-12-31 2004-07-15 Pharmacia & Upjohn Company Llc Canine l-pbe sequences
WO2004058957A2 (en) * 2002-12-31 2004-07-15 Pharmacia & Upjohn Company Llc Canine cyp1a2 sequences
JP2006518989A (ja) * 2002-12-31 2006-08-24 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー イヌのダイオキシン／アリール炭化水素受容体配列
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
CN102021205A (zh) 2003-01-17 2011-04-20 丹尼斯科公司 制备蛋白质酯和蛋白质亚基酯的方法
MXPA05007653A (es) 2003-01-17 2005-09-30 Danisco Metodo.
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
US20100143442A1 (en) 2003-02-05 2010-06-10 Queensland University Of Technology Growth factor complexes and modulation of cell migration and growth
AU2003900481A0 (en) 2003-02-05 2003-02-20 Queensland University Of Technology Synthetic modulators of cell migration and growth
US7157551B2 (en) * 2003-02-14 2007-01-02 Cephalon, Inc. Compositions and methods for the detection and treatment of methylthioadenosine phosphorylase deficient cancers
US20060141470A1 (en) * 2003-02-14 2006-06-29 Kalayoglu Murat V Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof
EP1599608A4 (de) * 2003-03-05 2007-07-18 Genetic Technologies Ltd Identifizierung fötaler dna und fötaler zellmarker im mütterlichen plasma oder serum
EP1603511B1 (de) 2003-03-07 2011-01-26 New England Medical Center Hospitals, Inc. Behandlung von igai-ablagerungserkrankungen
US7795220B2 (en) * 2003-03-19 2010-09-14 The General Hospital Corporation Conformationally constrained parathyroid hormones with alpha-helix stabilizers
AU2003901325A0 (en) 2003-03-21 2003-04-03 Stephen Locarnini Therapeutic, prophylactic and diagnostic agents
US20070043512A1 (en) * 2003-03-26 2007-02-22 Michael Rolph Therapeutic and prophylactic compositions and uses therefor
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
ATE517926T1 (de) 2003-04-04 2011-08-15 Yeda Res & Dev Antikörper zur hemmung der aktivität von mmp-2 und mmp-9
EA009643B1 (ru) * 2003-04-16 2008-02-28 Йейл Юниверсити Лечение состояний, включающих амилоидные бляшки
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
JPWO2004106930A1 (ja) * 2003-05-27 2006-07-20 株式会社三菱化学ヤトロン イムノクロマトグラフ法
US20060246526A1 (en) * 2003-06-02 2006-11-02 Gyros Patent Ab Microfluidic affinity assays with improved performance
WO2004110384A2 (en) * 2003-06-12 2004-12-23 Vaxgen, Inc. Hiv-1 envelope glycoproteins having unusual disulfide structure
US7910544B2 (en) 2003-07-17 2011-03-22 The General Hospital Corporation Conformationally constrained parthyroid hormone (PTH) analogs
US20050014734A1 (en) * 2003-07-18 2005-01-20 Genovate Biotechnology Co., Ltd. Modulation of interleukin-10 by DHEA
US7476399B2 (en) 2003-08-06 2009-01-13 Senomyx Inc. Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
WO2005014795A2 (en) 2003-08-08 2005-02-17 Genenews Inc. Osteoarthritis biomarkers and uses thereof
US20050064479A1 (en) * 2003-08-12 2005-03-24 Affymetrix, Inc. Compounds and methods for post incorporation labeling of nucleic acids
CA2535901A1 (en) 2003-08-14 2005-02-24 Exelixis, Inc. Ups as modifiers of the beta catenin pathway and methods of use
US7517495B2 (en) 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
JP4711963B2 (ja) 2003-09-15 2011-06-29 オクラホマ メディカル リサーチ ファウンデーション 炎症性疾患および自己免疫疾患を診断、治療および評価するためにサイトカインアッセイを用いる方法
AU2004272747A1 (en) 2003-09-18 2005-03-24 Genmab A/S Differentially expressed tumour-specific polypeptides for use in the diagnosis and treatment of cancer
JP4933258B2 (ja) 2003-09-22 2012-05-16 クイデル コーポレーション 試料中の複数分析物の検出装置
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
US20050079484A1 (en) * 2003-10-10 2005-04-14 Heineman William Richard Method of detecting biological materials in liquid
CA2542542C (en) 2003-10-21 2015-09-15 Orion Genomics Llc Method of detecting a quantity of methylation at a locus
US20050227251A1 (en) 2003-10-23 2005-10-13 Robert Darnell Method of purifying RNA binding protein-RNA complexes
AR046833A1 (es) 2003-11-10 2005-12-28 Schering Corp Anticuerpos anti-interleuquina-10
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
ATE468356T1 (de) 2003-11-25 2010-06-15 Us Gov Health & Human Serv Mutierte anti-cd22-antikörper und immunkonjugate
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
AU2004308964B2 (en) 2003-12-23 2010-09-16 Arbor Vita Corporation Antibodies for oncogenic strains of HPV and methods of their use
US7863053B2 (en) * 2003-12-23 2011-01-04 Kimberly-Clark Worldwide, Inc. Swab-based diagnostic systems
US7098040B2 (en) * 2003-12-23 2006-08-29 Kimberly-Clark Worldwide, Inc. Self-contained swab-based diagnostic systems
GB0716126D0 (en) * 2007-08-17 2007-09-26 Danisco Process
KR101169265B1 (ko) 2003-12-24 2012-08-02 대니스코 에이/에스 단백질
WO2008090395A1 (en) 2007-01-25 2008-07-31 Danisco A/S Production of a lipid acyltransferase from transformed bacillus licheniformis cells
US7718408B2 (en) * 2003-12-24 2010-05-18 Danisco A/S Method
US7150995B2 (en) 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
US20050186646A1 (en) * 2004-01-26 2005-08-25 Cruz Miguel A. Rapid assay to detect ADAMTS-13 activity
EP1713900A4 (de) * 2004-01-27 2009-06-17 Compugen Ltd Verfahren und systeme zur kommentierung biomolekularer sequenzen
US7638093B2 (en) * 2004-01-28 2009-12-29 Dnt Scientific Research, Llc Interrupted flow rapid confirmatory immunological testing device and method
US20080227220A1 (en) * 2004-01-29 2008-09-18 Maartje-Maria Franse Lateral Flow Binding Assay
US20070178462A1 (en) * 2004-02-18 2007-08-02 Uebele Victor N Nucleic acid molecules encoding novel murine low-voltage activated calcium channel proteins, designated-alpha1h, encoded proteins and methods of use thereof
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
WO2005085475A1 (en) 2004-03-01 2005-09-15 Applera Corporation Methods, compositions and kits for use in polynucleotide amplification
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
LT2712617T (lt) 2004-03-12 2017-01-25 Intercept Pharmaceuticals, Inc. Fibrozės gydymas, naudojant fxr ligandus
EP1733232A1 (de) * 2004-03-23 2006-12-20 Quidel Corporation Hybridphasen-lateralfluss-test
CA2955027A1 (en) 2004-04-15 2005-11-10 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders
AU2005240002B2 (en) 2004-04-23 2009-06-18 Zoetis Services Llc Cellular permissivity factor for viruses, and uses thereof
US7815854B2 (en) 2004-04-30 2010-10-19 Kimberly-Clark Worldwide, Inc. Electroluminescent illumination source for optical detection systems
US7796266B2 (en) 2004-04-30 2010-09-14 Kimberly-Clark Worldwide, Inc. Optical detection system using electromagnetic radiation to detect presence or quantity of analyte
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
EP2400030B1 (de) 2004-05-18 2016-01-20 The Board of Trustees of the Leland Stanford Junior University Detektion von Proteintranslokation durch Beta-Galactosidase-Reporter-Fragmentkomplementierung
JP4651663B2 (ja) 2004-05-28 2011-03-16 アジェンシス，インコーポレイテッド Ｐｓｃａタンパク質に結合する抗体および関連分子
WO2005121798A1 (en) * 2004-06-03 2005-12-22 Meso Scale Technologies, Llc Methods and apparatuses for conducting assays
EP2527447A1 (de) 2004-06-03 2012-11-28 Athlomics Pty Ltd Mittel und Verfahren zur Diagnose von Stress
WO2006002262A2 (en) 2004-06-21 2006-01-05 The Board Of Trustees Of The Leland Stanford Junior University Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder
US8034553B2 (en) 2004-06-24 2011-10-11 Kimberly-Clark Worldwide, Inc. Biomarkers for wound healing
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
US7763454B2 (en) 2004-07-09 2010-07-27 Church & Dwight Co., Inc. Electronic analyte assaying device
EP2267108A1 (de) 2004-07-16 2010-12-29 Danisco A/S Enzymatisches Ölentschleimungsverfahren
US20090226552A1 (en) * 2004-07-22 2009-09-10 Colorado State University Research Foundation Agents and methods for diagnosing osteoarthritis
CA2579790A1 (en) * 2004-07-30 2006-02-09 Mount Sinai School Of Medicine Of New York University Npc1l1 and npc1l1 inhibitors and methods of use thereof
WO2006017621A2 (en) * 2004-08-02 2006-02-16 Janssen Pharmaceutica N.V. IRAK1c SPLICE VARIANT AND ITS USE
US20060073168A1 (en) * 2004-08-11 2006-04-06 Stephens David S Neisseria meningitidis serogroup a capsular polysaccharide acetyltransferase, methods and compositions
US7598080B2 (en) * 2004-08-20 2009-10-06 Carl Deirmengian Diagnostic assay for source of inflammation
US7893197B2 (en) * 2004-08-25 2011-02-22 Janssen Pharmaceutica N.V. Relaxin-3 chimeric polypeptides and their preparation and use
WO2006021894A2 (en) 2004-08-26 2006-03-02 Engeneic Gene Therapy Pty Limited Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells
ES2345993T3 (es) 2004-09-14 2010-10-07 The Regents Of The University Of Colorado, A Body Corporate Metodo para el tratamiento con bucindolol basado en direccionamiento genetico.
CN101043891A (zh) 2004-09-18 2007-09-26 巴尔的摩马里兰大学 靶向NCCa－ATP通道的治疗剂及其使用方法
AU2005287090A1 (en) 2004-09-18 2006-03-30 Department Of Veterans Affairs Therapeutic agents targeting the NCca-ATP channel and methods of use thereof
US8685711B2 (en) 2004-09-28 2014-04-01 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
US9040305B2 (en) 2004-09-28 2015-05-26 Singulex, Inc. Method of analysis for determining a specific protein in blood samples using fluorescence spectrometry
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
US7390489B2 (en) 2004-10-08 2008-06-24 Komed Co., Ltd. Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
GB0423139D0 (en) 2004-10-18 2004-11-17 Danisco Enzymes
WO2006047417A2 (en) 2004-10-21 2006-05-04 University Of Florida Research Foundation, Inc. Detection of cannabinoid receptor biomarkers and uses thereof
EP1814573B1 (de) 2004-10-29 2016-03-09 ratiopharm GmbH Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf)
JP5525689B2 (ja) * 2004-11-02 2014-06-18 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ 過剰増殖性障害を処置するための組成物および方法
ATE520029T1 (de) * 2004-11-05 2011-08-15 Hoffmann La Roche Biochemisches gerät und nachweisverfahren
GB0424940D0 (en) 2004-11-11 2004-12-15 Danisco Transcription factors
WO2006055635A2 (en) * 2004-11-15 2006-05-26 Mount Sinai School Of Medicine Of New York University Compositions and methods for altering wnt autocrine signaling
EP1812594B1 (de) 2004-11-18 2013-01-09 Eppendorf Array Technologies Echtzeitquantifizierung mehrerer ziele auf einem mikro-array
US7465587B2 (en) * 2004-12-03 2008-12-16 Genzyme Corporation Diagnostic assay device
DE602005025685D1 (de) 2004-12-03 2011-02-10 Schering Corp Biologische marker zur vorauswahl von patienten für die anti-igf1r-therapie
US20060205012A1 (en) 2004-12-09 2006-09-14 Meso Scale Technologies, Llc Diagnostic test
US7387890B2 (en) * 2004-12-16 2008-06-17 Chembio Diagnostic Systems, Inc. Immunoassay devices and use thereof
US7504769B2 (en) * 2004-12-16 2009-03-17 E. I. Du Pont De Nemours + Company Aromatic chalcogen compounds and their use
US7960513B2 (en) 2004-12-17 2011-06-14 Monash University Antibody against a human ADAM protease
US7682817B2 (en) * 2004-12-23 2010-03-23 Kimberly-Clark Worldwide, Inc. Microfluidic assay devices
US8697674B2 (en) 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
JP4004505B2 (ja) * 2005-01-11 2007-11-07 富士フイルム株式会社 流路部材及びセンサユニット
US9568471B2 (en) 2005-01-25 2017-02-14 The Johns Hopkins University Plasmodium diagnostic assay device
EP2153848A3 (de) 2005-01-27 2010-07-21 The Regents of the University of California Monoklonale therapeutische Antikörper zur Neutralisierung von Botulin-Neurotoxinen
US20060292700A1 (en) * 2005-06-22 2006-12-28 Naishu Wang Diffused interrupted lateral flow immunoassay device and method
CN103497993A (zh) 2005-02-07 2014-01-08 基因信息公司 轻度骨关节炎生物标志物及其用途
GB0503546D0 (en) * 2005-02-21 2005-03-30 Hellenic Pasteur Inst Antibody
US7189522B2 (en) 2005-03-11 2007-03-13 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
WO2006098804A2 (en) 2005-03-11 2006-09-21 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
US7939342B2 (en) * 2005-03-30 2011-05-10 Kimberly-Clark Worldwide, Inc. Diagnostic test kits employing an internal calibration system
RU2413735C2 (ru) 2005-03-31 2011-03-10 Эдженсис, Инк. Антитела и родственные молекулы, связывающиеся с белками 161p2f10b
US8048638B2 (en) * 2005-04-01 2011-11-01 University Of Florida Research Foundation, Inc. Biomarkers of liver injury
JP5202296B2 (ja) * 2005-04-01 2013-06-05 ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイティド 肝臓傷害のバイオマーカー
RS61229B1 (sr) 2005-04-04 2021-01-29 Biogen Ma Inc Metodi evaluacije imunskog odgovora na terapijsko sredstvo
US9187546B2 (en) 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20130022979A1 (en) 2005-04-18 2013-01-24 Genesis Genomics Inc. 3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER
CN101248180B (zh) 2005-04-18 2013-09-25 米托米克斯公司 作为检测日光照射、前列腺癌和其它癌症的诊断工具的线粒体突变及重排
US7439079B2 (en) * 2005-04-29 2008-10-21 Kimberly-Clark Worldwide, Inc. Assay devices having detection capabilities within the hook effect region
US7858384B2 (en) 2005-04-29 2010-12-28 Kimberly-Clark Worldwide, Inc. Flow control technique for assay devices
US7803319B2 (en) 2005-04-29 2010-09-28 Kimberly-Clark Worldwide, Inc. Metering technique for lateral flow assay devices
US20070021433A1 (en) 2005-06-03 2007-01-25 Jian-Qiang Fan Pharmacological chaperones for treating obesity
ES2565670T3 (es) 2005-06-20 2016-04-06 Advanced Cell Diagnostics, Inc. Métodos de detección de ácidos nucleicos en células individuales y de identificación de células raras en grandes poblaciones de células heterogéneas
EP1910565A4 (de) 2005-07-07 2009-10-28 Athlomics Pty Ltd Polynukleotidmarkergene und deren expression zur diagnose von endotoxämie
US20070015166A1 (en) * 2005-07-14 2007-01-18 Nilsen Thor W Lateral flow methods and devices for detection of nucleic acid binding proteins
WO2007019541A2 (en) * 2005-08-08 2007-02-15 Onconon, Llc. Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility
US20070042504A1 (en) * 2005-08-22 2007-02-22 Yimin Yu Method for determining substance or substances in liquid sample
US7829347B2 (en) * 2005-08-31 2010-11-09 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
SG165322A1 (en) 2005-08-31 2010-10-28 Schering Corp Engineered anti-il-23 antibodies
WO2007030560A2 (en) * 2005-09-08 2007-03-15 Philadelphia Health & Education Corporation, D/B/A Drexel University College Of Medicine Identification of modulators of serine protease inhibitor kazal and their use as anti-cancer and anti-viral agents
US7608395B2 (en) 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
WO2007041340A2 (en) * 2005-09-30 2007-04-12 The Trustees Of Columbia University In The City Of New York Microfluidic cells with parallel arrays of individual dna molecules
IL172297A (en) 2005-10-03 2016-03-31 Compugen Ltd Soluble vegfr-1 variants for the diagnosis of preeclampsia
US20070202515A1 (en) * 2005-10-12 2007-08-30 Pathologica, Llc. Promac signature application
US7910381B2 (en) * 2005-10-13 2011-03-22 BioAssay Works Immuno gold lateral flow assay
US8153444B2 (en) * 2005-10-13 2012-04-10 Auric Enterprises, Llc Immuno gold lateral flow assay
US7344893B2 (en) * 2005-10-13 2008-03-18 Auric Enterprises, Llc Immuno-gold lateral flow assay
WO2007048092A2 (en) * 2005-10-17 2007-04-26 Spidertech, A Division Of Stoecker & Associates, A Subsidiary Of The Dermatology Center, Llc Immunoassay for venom detection including noninvasive sample collection
EP1945816B1 (de) 2005-10-21 2011-07-27 GeneNews Inc. Verfahren und vorrichtung zur korrelierung der ebenen von biomarker-produkten mit erkrankungen
MX2008005405A (es) * 2005-10-28 2008-09-11 Florida Internat University Bo Anticuerpos quimericos equinos: humanos.
US20100028358A1 (en) 2005-11-07 2010-02-04 Wolfram Ruf Compositions and Methods for Controlling Tissue Factor Signaling Specificity
JP5366554B2 (ja) 2005-11-12 2013-12-11 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー うつを診断および処置するためのｆｇｆ２関連方法
DE212006000071U1 (de) 2005-11-18 2008-07-24 Board of Regents, The University of Texas System, Austin Quantifizierung von Fusionsproteinen und ihrer Aktivität in Folge chromosomaler Translokation
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
WO2008002462A2 (en) * 2006-06-23 2008-01-03 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US8158360B2 (en) 2005-12-08 2012-04-17 Novartis Ag Effects of inhibitors of FGFR3 on gene transcription
US20070134814A1 (en) * 2005-12-09 2007-06-14 Kajander E O Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
US7279136B2 (en) 2005-12-13 2007-10-09 Takeuchi James M Metering technique for lateral flow assay devices
US7618810B2 (en) 2005-12-14 2009-11-17 Kimberly-Clark Worldwide, Inc. Metering strip and method for lateral flow assay devices
US7745158B2 (en) * 2005-12-14 2010-06-29 Kimberly-Clark Worldwide, Inc. Detection of secreted aspartyl proteases from Candida species
EP2674440B1 (de) 2005-12-16 2019-07-03 IBC Pharmaceuticals, Inc. Polyvalente bioaktive anordnungen auf immunglobulinbasis
MX338460B (es) 2005-12-21 2016-04-15 Meso Scale Technologies Llc Aparatos, metodos y reactivos de ensayo.
EP3153860A3 (de) 2005-12-22 2017-06-14 Abbott Molecular Inc. Verfahren und markerkombinationen zur untersuchung auf veranlagung von lungenkrebs
US9347945B2 (en) 2005-12-22 2016-05-24 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
US20090053694A1 (en) * 2005-12-26 2009-02-26 Kriksunov Leo B Photochemically Amplified Bioassay
US7465544B2 (en) * 2006-01-11 2008-12-16 Wisconsin Alumni Research Foundation Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use
US20100184021A1 (en) 2006-01-16 2010-07-22 Compugen Ltd. Novel nucleotide and amino acid sequences, and methods of use thereof for diagnosis
US7794656B2 (en) 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
US7871568B2 (en) 2006-01-23 2011-01-18 Quidel Corporation Rapid test apparatus
JP5829373B2 (ja) 2006-01-27 2015-12-09 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． Ｎｏｇｏレセプターアンタゴニスト
WO2007088051A2 (en) 2006-01-31 2007-08-09 Bayer Schering Pharma Aktiengesellschaft Modulation of mdl-1 activity for treatment of inflammatory disease
AU2007211846B2 (en) 2006-02-03 2013-05-23 The University Of Sydney A method of modulating cellular activity and agents for use therein
PL1986661T3 (pl) 2006-02-08 2019-02-28 Genzyme Corporation Terapia genowa choroby Niemanna-Picka typu A
US20070224701A1 (en) * 2006-02-16 2007-09-27 Becton, Dickinson And Company Combination vertical and lateral flow immunoassay device
PL2676967T3 (pl) 2006-02-28 2019-12-31 Biogen Ma Inc. Metody leczenia chorób zapalnych i autoimmunologicznych za pomocą natalizumabu
US20070231319A1 (en) 2006-03-03 2007-10-04 Yednock Theodore A Methods of treating inflammatory and autoimmune diseases with natalizumab
WO2007109733A2 (en) 2006-03-21 2007-09-27 The Johns Hopkins University Diagnostic and prognostic markers and treatment strategies for multiple sclerosis
US20070232556A1 (en) * 2006-03-31 2007-10-04 Montine Thomas J Methods and compositions for the treatment of neurological diseases and disorders
EP3156799B1 (de) 2006-04-04 2024-01-24 Novilux, LLC Analysator und verfahren zur hochempfindlichen detektion von analyten
EP2002260B1 (de) 2006-04-04 2015-11-04 Singulex, Inc. Hochsensitives system und verfahren zur troponinanalyse
MX2008012754A (es) * 2006-04-07 2009-04-27 Us Gov Health & Human Serv Composiciones de anticuerpos y metodos para tratamiento de enfermedad neoplastica.
EP2010009B1 (de) 2006-04-21 2017-06-14 Senomyx, Inc. Verfahren zur herstellung von festen geschmackstoffzusammensetzungen
FR2900341B1 (fr) 2006-04-27 2012-09-14 Centre Nat Rech Scient Utilisation de ligands synthetiques multivalents de la nucleoline de surface pour le traitement du cancer
RU2008148308A (ru) * 2006-05-09 2010-06-20 Маск Фаундейшн Фор Рисерч Дивелопмент (Us) Определение диастолической сердечной недостаточности при помощи профилей протеазы и ингибитора протеазы в плазме
US20080003230A1 (en) 2006-07-03 2008-01-03 Adair Charles D Composition for modulating the expression of cell adhesion molecules
US20080026394A1 (en) * 2006-07-11 2008-01-31 Antara Biosciences Inc. Methods of detecting one or more cancer markers
US8445222B2 (en) * 2006-07-11 2013-05-21 Musc Foundation For Research Development Predicting heart failure following myocardial infarction by protease and protease inhibitor profiling
WO2008010934A2 (en) 2006-07-14 2008-01-24 Chemocentryx, Inc. Triazolyl phenyl benzenesulfonamides
WO2008019062A2 (en) * 2006-08-04 2008-02-14 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
EP2053961A4 (de) * 2006-08-09 2013-05-01 Biogen Idec Inc Verfahren zur verbreitung eines wirkstoffs
JP2008043332A (ja) 2006-08-17 2008-02-28 Panomics Inc 組織スライドからの核酸定量
EP2423332A1 (de) 2006-08-25 2012-02-29 Oncotherapy Science, Inc. Prognosemarker und therapeutische Targets für Lungenkrebs
JP2008111824A (ja) * 2006-09-01 2008-05-15 Nox Technologies Inc 腫瘍特異的ｔＮＯＸアイソフォーム及び方法
US7951776B2 (en) 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
US7985542B2 (en) 2006-09-07 2011-07-26 Institut Pasteur Genomic morse code
ES2457243T3 (es) * 2006-09-08 2014-04-25 The Chancellor, Masters And Scholars Of The University Of Oxford Diagnóstico clínico de una fibrosis hepática utilizando APOL1 de suero humano como biomarcador
US7569396B1 (en) 2006-09-08 2009-08-04 Purplecow Llc Caffeine detection using internally referenced competitive assays
US8055034B2 (en) * 2006-09-13 2011-11-08 Fluidigm Corporation Methods and systems for image processing of microfluidic devices
US8050516B2 (en) * 2006-09-13 2011-11-01 Fluidigm Corporation Methods and systems for determining a baseline during image processing
EP2074230B1 (de) * 2006-10-11 2012-11-28 Janssen Pharmaceutica NV Zusammensetzungen und verfahren zur behandlung und diagnose von reizkolon
EP1912067A1 (de) * 2006-10-12 2008-04-16 Eppendorf Array Technologies S.A. Verfahren zur Quantifizierung eines Analyten in einer biologischen Probe durch Microarray-Chips
EP2426199A3 (de) 2006-10-20 2012-08-22 Danisco US Inc. Polyoloxidasen
US20080305512A1 (en) * 2006-10-26 2008-12-11 Mattingly Phillip G Assay for cardiac troponin autoantibodies
US7776605B2 (en) * 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
WO2008051762A2 (en) * 2006-10-26 2008-05-02 Abbott Laboratories Immunoassay of analytes in samples containing endogenous anti-analyte antibodies
WO2008049930A2 (en) 2006-10-27 2008-05-02 Janssen Pharmaceutica Nv A method for profiling kinase inhibitors
WO2008066655A2 (en) 2006-11-02 2008-06-05 Yale University Assessment of oocyte competence
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
ATE555128T1 (de) 2006-11-30 2012-05-15 Res Dev Foundation Verbesserte immunglobulin-bibliotheken
WO2008067552A2 (en) * 2006-11-30 2008-06-05 Fluidigm Corporation Method and apparatus for biological sample analysis
US20080138842A1 (en) * 2006-12-11 2008-06-12 Hans Boehringer Indirect lateral flow sandwich assay
US8232372B2 (en) 2006-12-14 2012-07-31 Schering Corp. Engineered anti-TSLP antibody
US8377379B2 (en) 2006-12-15 2013-02-19 Kimberly-Clark Worldwide, Inc. Lateral flow assay device
US7935538B2 (en) 2006-12-15 2011-05-03 Kimberly-Clark Worldwide, Inc. Indicator immobilization on assay devices
US8506499B2 (en) * 2007-01-04 2013-08-13 Musc Foundation For Research Development Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling
AU2008204338B2 (en) * 2007-01-11 2014-03-06 Erasmus University Medical Center Circular chromosome conformation capture (4C)
WO2008089103A2 (en) 2007-01-12 2008-07-24 University Of Maryland, Baltimore Targeting ncca-atp channel for organ protection following ischemic episode
ES2378490T3 (es) 2007-01-26 2012-04-13 University Of Louisville Research Foundation, Inc. Métodos de detección de autoanticuerpos para diagnosticar y caracterizar trastornos
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
KR100855299B1 (ko) * 2007-02-16 2008-08-29 건국대학교 산학협력단 인간 ｉｌ-32 특이 항원결정기를 갖는 단일클론항체,특이항체분비 융합 세포주 및 항체들을 이용한 ｉｌ-32측정법
SG178804A1 (en) 2007-02-23 2012-03-29 Schering Corp Engineered anti-il-23p19 antibodies
DK2426144T3 (en) 2007-02-23 2019-01-07 Merck Sharp & Dohme Manipulated Anti-IL-23P19 Antibodies
BRPI0807991A2 (pt) 2007-02-28 2014-06-17 Schering Corp Anticorpos anti-il-23r elaborados.
US7776618B2 (en) * 2007-03-01 2010-08-17 Church & Dwight Co., Inc. Diagnostic detection device
WO2008110006A1 (en) 2007-03-12 2008-09-18 Miraculins Inc. Biomarkers of prostate cancer and uses thereof
WO2008118324A2 (en) 2007-03-26 2008-10-02 Macrogenics, Inc. Composition and method of treating cancer with an anti-uroplakin ib antibody
US20100143905A1 (en) * 2007-03-29 2010-06-10 Lane Michael J Methods and compositions for multivalent binding and methods for manufacture of rapid diagnostic tests
EP2532746A3 (de) 2007-03-30 2013-08-14 EnGeneIC Molecular Delivery Pty Ltd. Von Bakterien stammende, intakte Minizellen, welche plasmidfreie funktionelle Nukleinsäuren enthalten, zur In-vivo-Verabreichung an Säugetierzellen
EP2132333B1 (de) 2007-04-06 2011-11-23 Becton, Dickinson and Company Zusammensetzungen und verfahren zur identifikation eines carbapenemase-gens
CA2683559C (en) 2007-04-13 2019-09-24 Dana Farber Cancer Institute, Inc. Methods for treating cancer resistant to erbb therapeutics
US8003314B2 (en) 2007-04-16 2011-08-23 Diagnostic Hybrids, Inc. Methods for direct fluorescent antibody virus detection in liquids
CA2684998A1 (en) 2007-04-30 2009-01-29 Nanogen, Inc. Multianalyte assay
AU2008247819B2 (en) 2007-05-01 2013-02-14 Research Development Foundation Immunoglobulin Fc libraries
WO2009009215A2 (en) * 2007-05-02 2009-01-15 Emory University Enhancement of glycoprotein incorporation into virus-like particles
JP2010529127A (ja) 2007-06-05 2010-08-26 イエール ユニバーシティ 受容体型チロシンキナーゼの阻害物質およびその使用方法
EP2716656B1 (de) 2007-06-15 2016-10-12 Xiamen University An Hämagglutinin des Vogelgrippevirus Subtyp H5 bindende monoklonale Antikörper und Verwendung dafür
US7776877B2 (en) 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
WO2009000089A1 (en) * 2007-06-28 2008-12-31 University Of Saskatchewan Immunomodulatory compositions and methods for treating disease with modified host defense peptides
ES2383568T3 (es) 2007-07-12 2012-06-22 Chemocentryx, Inc. Heteroaril piridil y fenil bencenosulfonamidas condensadas como moduladores de CCR2 para el tratamiento de la inflamación
WO2009014726A1 (en) 2007-07-26 2009-01-29 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
BRPI0814962B8 (pt) 2007-08-01 2021-05-25 Chugai Pharmaceutical Co Ltd métodos in vitro para determinar se um composto candidato é um agonista de longa duração ou de curta duração de um receptor acoplado à proteína g, polipeptídeo, seu uso e composição farmacêutica
JP5797403B2 (ja) 2007-08-03 2015-10-21 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント ヒトモノクローナル抗体およびそれを産生する方法
US8420315B2 (en) 2007-08-06 2013-04-16 Orion Genomics Llc Single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the IGF2 gene
US20120028880A1 (en) 2007-08-08 2012-02-02 Renata Pasqualini Vegfr-1/nrp-1 targeting peptides
WO2009023676A1 (en) 2007-08-12 2009-02-19 Integrated Dna Technologies, Inc. Microarray system with improved sequence specificity
WO2009023733A1 (en) * 2007-08-13 2009-02-19 Trustees Of Tufts College Methods and microarrays for detecting enteric viruses
US20090087860A1 (en) * 2007-08-24 2009-04-02 Todd John A Highly sensitive system and methods for analysis of prostate specific antigen (psa)
PL2769729T3 (pl) 2007-09-04 2019-09-30 Compugen Ltd. Polipeptydy i polinukleotydy i ich zastosowanie jako cel dla leków do wytwarzania leków i środków biologicznych
US8053198B2 (en) * 2007-09-14 2011-11-08 Meso Scale Technologies, Llc Diagnostic methods
EP3136103B1 (de) 2007-10-05 2018-08-29 Affymetrix, Inc. Stark gebündelte assays
US8535617B2 (en) * 2007-11-30 2013-09-17 Kimberly-Clark Worldwide, Inc. Blood cell barrier for a lateral flow device
US9103796B2 (en) * 2007-12-14 2015-08-11 Kimberly-Clark Worldwide, Inc. Multi-layered devices for analyte detection
US20090155753A1 (en) * 2007-12-14 2009-06-18 Kimberly-Clark Worldwide, Inc. Behavior Tracking with Tracking Pods
AU2008352940B2 (en) 2007-12-19 2014-06-05 Singulex, Inc. Scanning analyzer for single molecule detection and methods of use
BRPI0906429B1 (pt) 2008-01-10 2021-08-03 Research Development Foundation Método de identificação de uma infecção por e. chaffeensis em um indivíduo, uso de um ou mais polipeptídeo sintético e kit
US20110052501A1 (en) * 2008-01-31 2011-03-03 Liat Dassa Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
US20090196852A1 (en) * 2008-02-04 2009-08-06 Watkinson D Tobin Compositions and methods for diagnosing and treating immune disorders
CN101939019B (zh) 2008-02-07 2014-07-16 康奈尔大学 用于预防或治疗胰岛素抵抗性的方法
US20090311695A1 (en) * 2008-03-12 2009-12-17 Talat Nasim Method
JP2011519413A (ja) 2008-03-14 2011-07-07 イースタン バージニア メディカル スクール 改良された前立腺癌診断学のための質量顕微鏡法
US8993231B2 (en) * 2008-03-18 2015-03-31 Marshall University Research Corporation Methods for stem cell production and therapy
CA2719718C (en) 2008-03-28 2019-07-02 Mitomics, Inc. Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor
EP2107125A1 (de) 2008-03-31 2009-10-07 Eppendorf Array Technologies SA (EAT) Echtzeit-PCR von Targets auf einem Mikroarray
ES2654937T3 (es) 2008-04-02 2018-02-15 Macrogenics, Inc. Anticuerpos específicos para el complejo BCR y procedimientos de uso de los mismos
BRPI0906309A2 (pt) 2008-04-02 2020-05-26 Macrogenics, Inc Imunoglobulina, anticorpo, uso do anticorpo e composição farmacêutica
WO2009126303A2 (en) 2008-04-11 2009-10-15 Meso Scale Technologies, Llc Assay apparatuses, methods and reagents
GB0807161D0 (en) * 2008-04-18 2008-05-21 Danisco Process
EP2274592A4 (de) * 2008-04-23 2011-09-07 Luminex Corp Verfahren zur erzeugung eines standards für mehrere, in einem ausgangsmaterial biologischen ursprungs angetroffene analyten
CN102066579A (zh) * 2008-04-24 2011-05-18 纽约市哥伦比亚大学理事会 用于dna分子编排的几何图案和脂质双层以及它们的用途
DK2281034T3 (en) 2008-04-30 2016-01-25 Dupont Nutrition Biosci Aps A method using alcohol dehydrogenase Pseudoglucanobacter saccharoketogenes
BRPI0822661A2 (pt) * 2008-05-22 2015-06-30 Centre Nat Rech Scient Compostos oticamente puros para eficiência terapêutica melhorada
WO2010033279A2 (en) 2008-06-04 2010-03-25 Macrogenics, Inc. Antibodies with altered binding to fcrn and methods of using same
US8476008B2 (en) * 2008-07-23 2013-07-02 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes
US20100021472A1 (en) * 2008-07-25 2010-01-28 Geetha Srikrishna Methods for diagnosing and treating cancer
CN102124104A (zh) 2008-08-18 2011-07-13 财团法人首尔大学校产学协力财团 通过调节赖氨酰tRNA合成酶的细胞水平控制癌症转移或癌细胞移动的方法
GB2464183A (en) * 2008-09-19 2010-04-14 Singulex Inc Sandwich assay
WO2010036323A1 (en) 2008-09-25 2010-04-01 University Of Massachusetts Medical School Method of identifing interactions between genomic loci
US8101813B2 (en) * 2008-10-30 2012-01-24 Kimberly-Clark Worldwide, Inc. Training progress indicator
AU2009313255B2 (en) 2008-11-07 2014-08-07 Research Development Foundation Compositions and methods for the inhibition of Cripto/GRP78 complex formation and signaling
WO2010061393A1 (en) 2008-11-30 2010-06-03 Compugen Ltd. He4 variant nucleotide and amino acid sequences, and methods of use thereof
EP2194381B1 (de) 2008-12-03 2015-12-02 Roche Diagnostics GmbH Testelement mit kombinierter Kontroll- und Kalibrationszone
US20110287088A1 (en) 2008-12-03 2011-11-24 Research Development Foundation Modulation of olfml-3 mediated angiogenesis
WO2010065867A1 (en) 2008-12-04 2010-06-10 Pioneer Hi-Bred International, Inc. Methods and compositions for enhanced yield by targeted expression of knotted1
JP2012511032A (ja) 2008-12-05 2012-05-17 アブラクシス バイオサイエンス リミテッド ライアビリティー カンパニー ＳＰＡＲＣ結合ＳｃＦｖ
EP2373690B1 (de) 2008-12-08 2015-02-11 Compugen Ltd. Tmem154-spezifische antikörper
EP2373997A1 (de) 2008-12-09 2011-10-12 Dako Denmark A/S Verfahren zur bewertung einer vorbehandlung
WO2010068757A1 (en) 2008-12-12 2010-06-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods useful for detecting and treating diseases associated with 16p chromosomal disruptions
WO2010068747A1 (en) 2008-12-12 2010-06-17 University Of Florida Research Foundation, Inc. Cell-based detection of apf through its interaction with ckap4 for diagnosis of interstitial cystitis
US8692873B2 (en) 2009-01-15 2014-04-08 Alverix, Inc. Video-frame data receiver with low frame capture rate
US8422740B2 (en) 2009-01-15 2013-04-16 Scott Dylewski Methods for determining a liquid front position on a test strip
EP2396661A4 (de) 2009-02-11 2013-10-30 Caris Mpi Inc Molekulare profilierung von tumoren
EP2396429B1 (de) 2009-02-11 2015-05-27 Orion Genomics, LLC Kombinationen aus polymorphismen zur bestimmung von allelspezifischer igf2-expression
DE102009010563A1 (de) 2009-02-16 2010-08-26 Matthias W. Engel Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten
WO2010096658A1 (en) 2009-02-19 2010-08-26 The Cleveland Clinic Foundation Corin as a marker for heart failure
US20100240065A1 (en) * 2009-03-18 2010-09-23 Boehringer Ingelheim International Gmbh Prolyl Hydroxylase Compositions and Methods of Use Thereof
US8481698B2 (en) * 2009-03-19 2013-07-09 The President And Fellows Of Harvard College Parallel proximity ligation event analysis
EP2411522B1 (de) 2009-03-27 2017-09-06 MDNA Life Sciences Inc. Aberrante mitochondriale dna, entsprechende fusionstranskripte sowie übersetzungsprodukte und hybridisierungssonden dafür
TW201039841A (en) * 2009-03-27 2010-11-16 Gojo Ind Inc Compositions and methods for screening and using compounds antagonizing spore-surface interactions
US20100261292A1 (en) 2009-04-10 2010-10-14 Meso Scale Technologies, Llc Methods for Conducting Assays
CA2795268A1 (en) 2009-04-21 2010-10-28 Genetic Technologies Limited Methods for obtaining fetal genetic material
GB0908770D0 (en) 2009-04-24 2009-07-01 Danisco Method
US20120046197A1 (en) 2009-05-01 2012-02-23 Meso Scale Technologies, Llc Biomarkers of therapeutic responsiveness
WO2010124689A1 (en) 2009-05-01 2010-11-04 Dako Denmark A/S New antibody cocktail
US8168396B2 (en) 2009-05-11 2012-05-01 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes using differential protein glycosylation
WO2010132208A2 (en) 2009-05-13 2010-11-18 Meso Scale Technologies, Llc Diagnostic methods for liver disorders
CN102460174B (zh) 2009-05-14 2016-03-16 牛津大学之校长及学者 使用一组新型低丰度人类血浆蛋白生物标记对肝纤维化进行临床诊断
CA2761767A1 (en) 2009-05-19 2010-11-25 Danisco A/S Use of amylase and lipolytic enzyme in bread
EP2432499A2 (de) 2009-05-20 2012-03-28 Schering Corporation Modulation von pilr-rezeptoren zur behandlung mikrobieller infektionen
KR20120122869A (ko) 2009-06-02 2012-11-07 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 신경변성 질환을 갖는 대상에서 항체에 의해 인식되는 소분자의 확인법
US8802427B2 (en) * 2009-06-09 2014-08-12 Church & Dwight Co., Inc. Female fertility test
JP2012531197A (ja) 2009-06-25 2012-12-10 デュポン ニュートリション バイオサイエンシーズ エーピーエス タンパク質
JP6193570B2 (ja) 2009-07-17 2017-09-13 バイオアトラ、エルエルシー 産生宿主における抗体／タンパク質パフォーマンス及び発現の同時で統合された選択及び進化
US20110143947A1 (en) * 2009-07-27 2011-06-16 Meso Scale Technologies, Llc Assay Apparatuses, Consumables and Methods
ES2581178T3 (es) 2009-07-29 2016-09-01 Pharnext Nuevas herramientas de diagnóstico para enfermedad de Alzheimer
RU2595409C2 (ru) 2009-09-03 2016-08-27 Мерк Шарп И Доум Корп., Анти-gitr-антитела
US8900850B2 (en) * 2009-09-17 2014-12-02 Michael J. Lane Lateral flow based methods and assays for rapid and inexpensive diagnostic tests
WO2011038403A1 (en) 2009-09-28 2011-03-31 Yuling Luo Methods of detecting nucleic acid sequences with high specificity
CA2777053A1 (en) 2009-10-06 2011-04-14 The Board Of Trustees Of The University Of Illinois Human single-chain t cell receptors
US9377458B2 (en) 2009-10-11 2016-06-28 Biogen Ma Inc. Anti-VLA-4 related assays
US20160186266A1 (en) 2009-10-27 2016-06-30 Carislife Sciences, Inc. Molecular profiling for personalized medicine
GB0920089D0 (en) 2009-11-17 2009-12-30 Danisco Method
US8592151B2 (en) * 2009-11-17 2013-11-26 Musc Foundation For Research Development Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
CN102770529B (zh) 2009-11-17 2018-06-05 Musc研究发展基金会 针对人核仁素的人单克隆抗体
US9910040B2 (en) 2012-07-09 2018-03-06 Sevident, Inc. Molecular nets comprising capture agents and linking agents
US9733242B2 (en) 2012-10-07 2017-08-15 Sevident, Inc. Devices for capturing analyte
JP2013511960A (ja) 2009-11-30 2013-04-11 クイーンズランド ユニバーシティ オブ テクノロジー フィブロネクチン：増殖因子キメラ
US9428586B2 (en) 2009-12-01 2016-08-30 Compugen Ltd Heparanase splice variant
US8652788B2 (en) * 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
US8835120B2 (en) * 2009-12-02 2014-09-16 Abbott Laboratories Assay for cardiac troponin-T (cTnT)
US8183002B2 (en) 2009-12-03 2012-05-22 Abbott Laboratories Autoantibody enhanced immunoassays and kits
US20110136141A1 (en) 2009-12-03 2011-06-09 Abbott Laboratories Peptide reagents and method for inhibiting autoantibody antigen binding
WO2011084357A1 (en) 2009-12-17 2011-07-14 Schering Corporation Modulation of pilr to treat immune disorders
GB0922377D0 (en) 2009-12-22 2010-02-03 Arab Gulf University The Mutant LDL receptor
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
FI3339865T5 (fi) 2010-01-11 2023-04-15 Jc-viruksen vasta-aineiden määritys
CA2784919A1 (en) 2010-01-26 2011-07-26 Banyan Biomarkers, Inc. Compositions and methods relating to argininosuccinate synthetase
US8697078B2 (en) 2010-01-27 2014-04-15 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
WO2011094577A2 (en) 2010-01-29 2011-08-04 Micronics, Inc. Sample-to-answer microfluidic cartridge
ES2719502T3 (es) 2010-01-29 2019-07-10 Advanced Cell Diagnostics Inc Métodos de detección in situ de ácidos nucleicos
US8574832B2 (en) 2010-02-03 2013-11-05 Massachusetts Institute Of Technology Methods for preparing sequencing libraries
TWI518325B (zh) 2010-02-04 2016-01-21 自治醫科大學 對ａｌｋ抑制劑具有先抗性或後抗性癌症的識別、判斷和治療
TWI504410B (zh) 2010-02-08 2015-10-21 Agensys Inc 結合至１６１ｐ２ｆ１０ｂ蛋白之抗體藥物結合物（ａｄｃ）
WO2011106738A2 (en) 2010-02-25 2011-09-01 Fred Hutchinson Cancer Research Center Use of tcr clonotypes as biomarkers for disease
WO2011109398A2 (en) 2010-03-02 2011-09-09 President And Fellows Of Harvard College Methods and compositions for treatment of angelman syndrome and autism spectrum disorders
WO2011114251A1 (en) 2010-03-18 2011-09-22 Danisco A/S Foodstuff
US10706955B2 (en) 2010-03-23 2020-07-07 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
WO2011120013A2 (en) 2010-03-26 2011-09-29 Trustees Of Dartmouth College Vista regulatory t cell mediator protein, vista binding agents and use thereof
US9125931B2 (en) 2010-04-06 2015-09-08 Massachusetts Institute Of Technology Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers
SG184466A1 (en) 2010-04-06 2012-11-29 Massachusetts Inst Technology Gene-expression profiling with reduced numbers of transcript measurements
BR112012025728B1 (pt) 2010-04-09 2022-01-11 Critical Care Diagnostics, Inc Anticorpos isolados ou fragmentos que se liga a st2 humano solúvel, hibridoma, kit, bem como métodos para quantificação de um nível de st2 solúvel humano em uma amostra de um indivíduo, e para a predição do risco de morte dentro de um ano em um indivíduo
WO2011129382A1 (en) 2010-04-16 2011-10-20 Abbott Japan Co. Ltd. Methods and reagents for diagnosing rheumatoid arthritis
WO2011133450A2 (en) 2010-04-19 2011-10-27 Meso Scale Technologies, Llc. Serology assays
US10295472B2 (en) 2010-05-05 2019-05-21 Alverix, Inc. Assay reader operable to scan a test strip
US20120190563A1 (en) 2010-05-07 2012-07-26 Abbott Laboratories Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
MX2012012986A (es) 2010-05-07 2013-03-05 Abbvie Inc Metodos para predecir la sensibilidad al tratamiento con un inhibidor de cinasa de tirosina dirigido.
JP5941040B2 (ja) 2010-05-13 2016-06-29 ザ ジェネラル ホスピタル コーポレイション 副甲状腺ホルモン類似体およびその使用
EP2572197A4 (de) 2010-05-18 2013-08-28 Texas A & M Univ Sys Verfahren und zusammensetzungen zur diagnose und überwachung von entzündungskrankheiten
WO2011150186A1 (en) 2010-05-26 2011-12-01 The Board Of Trustees Of The University Of Illinois Personal glucose meters for detection and quantification of a broad range of analytes
WO2011156715A2 (en) 2010-06-10 2011-12-15 The Regents Of The University Of Michigan Methods of treating metabolic disorders and cardiovascular diseases
EP3327035A1 (de) 2010-06-22 2018-05-30 Precision Biologics Inc. Für dickdarm- und bauchspeicheldrüsenkrebs spezifische antigene und antikörper
US20130316338A1 (en) 2010-06-29 2013-11-28 The United States Government As Represented By The Department Of Veterans Affairs CCR6 As A Biomarker of Alzheimer's Disease
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
EP2407242A1 (de) 2010-07-13 2012-01-18 Dublin City University Direkte Klonanalyse und Auswahltechnologie
DK3435087T3 (da) 2010-07-16 2023-11-27 Bioatla Inc Hidtil ukendte fremgangsmåder til proteinevolution
CN103153467A (zh) 2010-07-16 2013-06-12 范德比尔特大学 用于提取、浓缩和检测分子物类的使用表面张力阀的低资源处理器
CA2806306A1 (en) 2010-07-23 2012-01-26 Luminex Corporation Co-coupling to control reactivity of reagents in immunoassays
US9120862B2 (en) 2010-07-26 2015-09-01 Abbott Laboratories Antibodies relating to PIVKA-II and uses thereof
USD656852S1 (en) 2010-08-06 2012-04-03 Kimberly-Clark Worldwide, Inc. Wetness indicator
US9018434B2 (en) 2010-08-06 2015-04-28 Kimberly-Clark Worldwide, Inc. Absorbent articles with intricate graphics
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
WO2012035518A1 (en) 2010-09-17 2012-03-22 Compugen Ltd. Compositions and methods for treatment of drug resistant multiple myeloma
AU2011305696A1 (en) 2010-09-20 2013-05-02 Advanced Cell Diagnostics, Inc. Biomarkers for differentiating melanoma from benign nevus in the skin
CA2812556C (en) 2010-09-23 2023-02-14 Xue-Ping Wang Colon and pancreas cancer peptidomimetics
WO2012040619A2 (en) 2010-09-24 2012-03-29 Massachusetts Eye And Ear Infirmary Methods and compositions for prognosing and/or detecting age-related macular degeneration
KR102504750B1 (ko) 2010-09-29 2023-03-02 어젠시스 인코포레이티드 191p4d12 단백질에 결합하는 항체 약물 컨쥬게이트(ａｄｃ)
AU2011311665A1 (en) 2010-10-04 2013-05-02 Centre National De La Recherche Scientifique (Cnrs) Compositions comprising multivalent synthetic ligands of surface nucleolin and glycosaminoglycans
EP2441520A1 (de) 2010-10-12 2012-04-18 Eppendorf AG Echtzeitverstärkungs- und Mikroarray-basierte Erkennung von Nukleinsäuretargets in einem Fluss-Chip-Assay
WO2012051386A2 (en) 2010-10-14 2012-04-19 Meso Scale Technologies, Llc Reagent storage in an assay device
ES2562821T3 (es) 2010-10-21 2016-03-08 Advanced Cell Diagnostics, Inc. Método ultrasensible para la detección in situ de ácidos nucleicos
AR084358A1 (es) 2010-12-27 2013-05-08 Lilly Co Eli Composiciones y metodos para identificar y diferenciar componentes virales de vacunas multivalentes de la “fiebre de embarque” (complejo de enfermedad respiratoria bovina (brdc))
US9220640B2 (en) 2010-12-30 2015-12-29 Kimberly-Clark Worldwide, Inc. Absorbent article including two dimensional code made from an active graphic
AU2011352207B2 (en) 2010-12-31 2016-03-03 Bioatla, Llc Comprehensive monoclonal antibody generation
EP3216878B1 (de) 2011-01-17 2019-04-03 Life Technologies Corporation Arbeitsablauf zur nachweis von liganden mit nukleinsäuren
EP2477032A1 (de) 2011-01-18 2012-07-18 Baxter International Inc Messung von Antiamyloid-Antikörper in Menschenblut
JP2014507649A (ja) 2011-01-18 2014-03-27 バクスター・インターナショナル・インコーポレイテッド ヒト血液中の抗βアミロイド抗体の測定
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
US20120214152A1 (en) 2011-01-28 2012-08-23 Xiao-Jun Ma Rnascope® hpv assay for determining hpv status in head and neck cancers and cervical lesions
EP2673299B1 (de) 2011-02-07 2017-05-10 Research Development Foundation Manipulierte immunglobulin-fc-polypeptide
US8603835B2 (en) 2011-02-10 2013-12-10 Chembio Diagnostic Systems, Inc. Reduced step dual path immunoassay device and method
US9212258B2 (en) 2011-02-23 2015-12-15 The Board Of Trustees Of The University Of Illinois Amphiphilic dendron-coils, micelles thereof and uses
EP2683835B1 (de) 2011-03-08 2017-01-11 King Abdullah University Of Science And Technology Molekulares biomarker-set zur früherkennung von eierstockkrebs
AU2012229156A1 (en) 2011-03-11 2013-10-31 Board Of Regents Of The University Of Nebraska Biomarker for coronary artery disease
US20140005070A1 (en) 2011-03-28 2014-01-02 Novartis Ag Markers associated with cyclin-dependent kinase inhibitors
SI2694106T1 (en) 2011-04-01 2018-04-30 Immunogen, Inc. Methods for increasing the effectiveness of treatment with FOLR1 receptor cancer
US9790262B2 (en) 2011-04-05 2017-10-17 Longevity Biotech, Inc. Compositions comprising glucagon analogs and methods of making and using the same
BR112013025811A2 (pt) 2011-04-08 2016-11-29 Danisco Us Inc "composição e método para remover uma mancha de base lipídica de uma superfície"
WO2012139058A1 (en) 2011-04-08 2012-10-11 Biogen Idec Ma Inc. BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO IFNβ AND USES THEREOF
WO2012142164A1 (en) 2011-04-12 2012-10-18 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
WO2012140627A1 (en) 2011-04-15 2012-10-18 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer
JP2014515476A (ja) 2011-05-20 2014-06-30 アボットジャパン株式会社 非特異的結合を減少させるためのイムノアッセイ方法及び試薬
JP6457263B2 (ja) 2011-05-20 2019-01-23 オリゴメリックス インコーポレイテッド タウプロテアーゼ組成物および使用方法
SG10201603962TA (en) 2011-05-25 2016-07-28 Innate Pharma Sa Anti-kir antibodies for the treatment of inflammatory disorders
EP3575792B1 (de) 2011-05-31 2022-11-30 Biogen MA Inc. Verfahren zur beurteilung eines pml-risikos
JP2014527036A (ja) 2011-06-27 2014-10-09 ザ ジャクソン ラボラトリー 癌および自己免疫疾患の処置のための方法および組成物
WO2013001517A1 (en) 2011-06-30 2013-01-03 Compugen Ltd. Polypeptides and uses thereof for treatment of autoimmune disorders and infection
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
WO2013010170A1 (en) 2011-07-14 2013-01-17 Lovell Mark A Process for detection of alzheimer's disease from a serum sample
CA2842321C (en) 2011-07-18 2022-05-03 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
AU2012294814A1 (en) 2011-08-05 2014-02-27 Research Development Foundation Improved methods and compositions for modulation of Olfml3 mediated angiogenesis
JP6317670B2 (ja) 2011-08-15 2018-04-25 ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ ブドウ球菌プロテインａに対する抗体に関連した組成物および方法
ES2704126T3 (es) 2011-08-23 2019-03-14 Found Medicine Inc Moléculas de fusión KIF5B-RET y usos de las mismas
EP2771349B1 (de) 2011-09-16 2020-02-26 Iogenetics, LLC. Bioinformatikverfahren zur bestimmung von peptidbindungen
KR101425032B1 (ko) * 2011-09-22 2014-07-31 재단법인 의약바이오컨버젼스연구단 류신 티알엔에이 합성효소의 신규한 용도
WO2013049455A1 (en) 2011-09-29 2013-04-04 William Blakely Biodosimetry panels and methods
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
US20130164217A1 (en) 2011-12-21 2013-06-27 Meso Scale Technologies, Llc Method of diagnosing, preventing and/or treating dementia & related disorders
EP2798081A1 (de) 2011-12-29 2014-11-05 Baylor Research Institute Biomarker für morbus kawasaki
JP6190822B2 (ja) 2012-01-09 2017-08-30 マイクロニクス， インコーポレイテッド マイクロ流体リアクタシステム
WO2013112216A1 (en) 2012-01-24 2013-08-01 Cd Diagnostics, Llc System for detecting infection in synovial fluid
GB201201314D0 (en) 2012-01-26 2012-03-07 Isis Innovation Composition
SG2014008304A (en) 2012-02-01 2014-06-27 Compugen Ltd C10rf32 antibodies, and uses thereof for treatment of cancer
US9567642B2 (en) 2012-02-02 2017-02-14 Massachusetts Institute Of Technology Methods and products related to targeted cancer therapy
EP2812704A4 (de) 2012-02-07 2016-03-23 Intuitive Biosciences Inc Mycobakteriumstuberkulose-spezifische peptide zur erkennung einer infektion oder immunisierung nichtmenschlicher primaten
WO2013130811A1 (en) 2012-02-29 2013-09-06 Chemocentryx, Inc. Pyrazol-1-yl benzene sulfonamides as ccr9 antagonists
US9567392B2 (en) 2012-03-20 2017-02-14 Biogen Ma Inc. JCV neutralizing antibodies
US9526800B2 (en) 2012-03-28 2016-12-27 Massachusetts Institute Of Technology Cancer-related extracellular matrix signatures and related methods and products
US10024860B2 (en) 2012-03-28 2018-07-17 Massachusetts Institute Of Technology Cancer-related extracellular matrix signatures and related methods and products
US20140178869A1 (en) 2012-04-05 2014-06-26 Advanced Cell Diagnostics, Inc. Detection of immunoglobulin light chain restriction by rna in situ hybridization
US20130280696A1 (en) 2012-04-23 2013-10-24 Elliott Millenson Devices and methods for detecting analyte in bodily fluid
CN104703622B (zh) 2012-04-26 2017-05-24 芝加哥大学 与金黄色葡萄球菌疾病期间抵消凝固酶活性的抗体相关的组合物和方法
MX2019001355A (es) 2012-05-10 2023-01-17 Bioatla Llc Anticuerpos monoclonales multiespecíficos.
SG11201408330XA (en) 2012-05-24 2015-01-29 Mountgate Group Ltd Compositions and methods related to prevention and treatment of rabies infection
CN104582770B (zh) 2012-06-01 2019-01-29 西奈山伊坎医学院 在感染的治疗和预防中的神经酰胺水平
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
CA2875710C (en) 2012-06-22 2021-06-29 John Wayne Cancer Institute Molecular malignancy in melanocytic lesions
AU2013277051B2 (en) 2012-06-22 2018-06-07 King's College London Novel VISTA-Ig constructs and the use of VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
ES2776365T3 (es) 2012-07-09 2020-07-30 Novartis Ag Biomarcadores asociados con inhibidores de CDK
US9651549B2 (en) 2012-07-13 2017-05-16 Genisphere, Llc Lateral flow assays using DNA dendrimers
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
WO2014014788A2 (en) 2012-07-18 2014-01-23 President And Fellows Of Harvard College Modification of surfaces for simulataneous repellency and targeted binding of desired moieties
IN2015DN00880A (de) 2012-07-27 2015-06-12 Univ Illinois
US20150159222A1 (en) 2012-07-31 2015-06-11 Novartis Ag Markers associated with human double minute 2 inhibitors
EP2880448B1 (de) 2012-08-03 2022-06-29 Foundation Medicine, Inc. Menschlicher papillomavirus als prädiktor einer krebsprognose
CA2882745C (en) 2012-08-23 2022-03-29 Agensys, Inc. Antibody drug conjugates (adc) that bind to 158p1d7 proteins
CN109793893B (zh) 2012-09-07 2023-05-26 达特茅斯大学理事会 用于诊断和治疗癌症的vista调节剂
WO2014043633A1 (en) 2012-09-17 2014-03-20 Agios Pharmaceuticals, Inc. Use of e-cadherin and vimentin for selection of treatment responsive patients
JP6324974B2 (ja) 2012-10-12 2018-05-23 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ アリゾナ ステート ユニバーシティ タウの毒性オリゴマー形態を特異的に認識する抗体ベースの試薬
US9395369B2 (en) 2012-10-19 2016-07-19 Regents Of The University Of Minnesota Guinea pig cytomegalovirus (CIDMTR strain)
EP2909230B1 (de) 2012-10-19 2019-05-22 Danisco US Inc. Verfahren zur stabilisierung von biometrischen membranen
US20150354006A1 (en) 2012-10-19 2015-12-10 Novartis Ag Markers for acute lymphoblastic leukemia
WO2014066590A1 (en) 2012-10-24 2014-05-01 Research Development Foundation Jam-c antibodies and methods for treatment of cancer
WO2014063205A1 (en) 2012-10-26 2014-05-01 The University Of Queensland Use of endocytosis inhibitors and antibodies for cancer therapy
AU2013337277B2 (en) 2012-11-05 2018-03-08 Foundation Medicine, Inc. Novel NTRK1 fusion molecules and uses thereof
WO2014071406A1 (en) 2012-11-05 2014-05-08 Pronai Therapeutics, Inc. Methods of using biomarkers for the treatment of cancer by modulation of bcl2|expression
CN104937106A (zh) 2012-11-21 2015-09-23 奥斯陆大学医院 用于监测生物流体的系统和方法
CA2892089A1 (en) 2012-11-21 2014-05-30 Rene M. Lemieux Glutaminase inhibitors and methods of use
WO2014079011A1 (en) 2012-11-22 2014-05-30 Agios Pharmaceuticals, Inc. Heterocyclic compounds for inhibiting glutaminase and their methods of use
KR20150096788A (ko) 2012-12-21 2015-08-25 마이크로닉스 인코포레이티드. 마이크로 유체공학 용도를 위한 저탄성 막
JP2016509206A (ja) 2012-12-21 2016-03-24 マイクロニクス， インコーポレイテッド 携帯型蛍光検出システムおよびマイクロアッセイカートリッジ
WO2014100732A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Fluidic circuits and related manufacturing methods
AU2013370171B2 (en) 2012-12-28 2018-09-13 Precision Biologics, Inc. Humanized monoclonal antibodies and methods of use for the diagnosis and treatment of colon and pancreas cancer
CN105008925B (zh) 2013-01-02 2017-09-26 N-Dia有限责任公司 预测孕妇分娩时间的方法
JP6416785B2 (ja) 2013-01-04 2018-10-31 メソ スケール テクノロジーズ エルエルシー マルチウェルプレートおよびコンタクトプラットフォームを利用した電気化学発光分析用計器
EP3939614A1 (de) 2013-01-18 2022-01-19 Foundation Medicine, Inc. Verfahren zur behandlung cholangiokarzinom
US8968677B2 (en) 2013-01-22 2015-03-03 Quantum Design International, Inc. Frazil ice conjugate assay device and method
WO2014116721A1 (en) 2013-01-22 2014-07-31 The Arizona Board Of Regents For And On Behalf Of Arizona State University Geminiviral vector for expression of rituximab
US20140309263A1 (en) 2013-02-01 2014-10-16 Meso Scale Technologies, Llc Biomarkers of therapeutic responsiveness
US9411930B2 (en) 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
GB2547875B (en) 2013-02-01 2017-12-13 Univ California Methods for meta-genomics analysis of microbes
US20140221368A1 (en) 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Biomarkers of therapeutic responsiveness
CA2899865C (en) 2013-02-01 2023-10-10 Kapil BHARTI Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs)
US20160008282A1 (en) 2013-02-22 2016-01-14 The Board Of Trustees Of The Universityof Illinois Transdermal Drug Delivery Using Amphiphilic Dendron-Coil Micelles
TWI582239B (zh) 2013-03-11 2017-05-11 諾華公司 與ｗｎｔ抑制劑相關之標記
WO2014159242A1 (en) 2013-03-14 2014-10-02 Novartis Ag Notch 3 mutants and uses thereof
EP2970479B1 (de) 2013-03-14 2019-04-24 Novartis AG Antikörper gegen notch 3
US9273349B2 (en) 2013-03-14 2016-03-01 Affymetrix, Inc. Detection of nucleic acids
EP2970909A4 (de) 2013-03-15 2017-02-15 The University of Chicago Verfahren und zusammensetzungen in zusammenhang mit t-zell aktivität
US9789164B2 (en) 2013-03-15 2017-10-17 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
WO2014145797A2 (en) 2013-03-15 2014-09-18 Adair Charles Method for treating eclampsia and preeclampsia
WO2014151683A1 (en) 2013-03-15 2014-09-25 Bayer Healthcare Llc Gla domains as targeting agents
US9878010B2 (en) 2013-03-21 2018-01-30 The Regents Of The University Of Michigan Methods of treating metabolic disorders
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
WO2014172390A2 (en) 2013-04-15 2014-10-23 Cedars-Sinai Medical Center Methods for detecting cancer metastasis
WO2014176306A1 (en) 2013-04-23 2014-10-30 Montecito Bio Sciences Ltd Flow through testing system with pressure indicator
US20160091485A1 (en) 2013-04-25 2016-03-31 The Broad Institute, Inc. Markers for ezh2 inhibitors
AR096203A1 (es) 2013-05-06 2015-12-16 Alnylam Pharmaceuticals Inc Dosificaciones y métodos para administrar moléculas de ácido nucleico formuladas en lípidos
US10190153B2 (en) 2013-05-07 2019-01-29 Micronics, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
WO2014182847A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Device for preparation and analysis of nucleic acids
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
GB201308658D0 (en) 2013-05-14 2013-06-26 Isis Innovation Antibodies
CA2913155A1 (en) 2013-05-21 2014-11-27 President And Fellows Of Harvard College Engineered heme-binding compositions and uses thereof
EP3004334A4 (de) 2013-05-28 2016-12-21 Biogen Ma Inc Verfahren zur beurteilung eines pml-risikos
US9442051B2 (en) * 2013-06-10 2016-09-13 Yingjian Wang Methods to accelerate the binding of biological molecules
ES2754177T3 (es) 2013-06-12 2020-04-16 Massachusetts Gen Hospital Métodos para la detección multiplexada de moléculas diana y sus usos
SG10201710528WA (en) 2013-06-18 2018-01-30 Dnatrix Inc Treatment of brain cancer with oncolytic adenovirus
US20160296609A1 (en) 2013-06-28 2016-10-13 Baylor Research Institute Dendritic cell asgpr targeting immunotherapeutics for multiple sclerosis
ES2964893T3 (es) 2013-07-17 2024-04-10 Found Medicine Inc Procedimientos de tratamiento de carcinomas uroteliales
US20150038365A1 (en) 2013-08-01 2015-02-05 Meso Scale Technologies, Llc Lung cancer biomarkers
EP3027220A1 (de) 2013-08-01 2016-06-08 Agensys, Inc. An cd37-proteine bindende antikörper-wirkstoffkonjugate (adc)
EP3036005A4 (de) 2013-08-21 2017-04-26 The Board Of Regents Of The University Of Texas System Zusammensetzungen und verfahren zur abzielung auf connexin-hemikanäle
IL293871A (en) 2013-08-30 2022-08-01 Immunogen Inc Antibodies and assays for the detection of folate receptor 1
CN105765384B (zh) 2013-09-13 2018-02-09 Symbolics有限责任公司 运用二维试验和对照信号读出模式的侧向层析检测
WO2015050959A1 (en) 2013-10-01 2015-04-09 Yale University Anti-kit antibodies and methods of use thereof
BR112016007391A2 (pt) 2013-10-03 2017-08-01 Oklahoma Med Res Found biomarcadores da atividade, da intensidade e da fase aguda da doença lúpus eritematoso sistêmico
US9476884B2 (en) 2013-10-04 2016-10-25 University Of Massachusetts Hybridization- independent labeling of repetitive DNA sequence in human chromosomes
WO2015063604A2 (en) 2013-11-01 2015-05-07 Imberti Luisa BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO IFNβ AND USES THEREOF
WO2015070009A2 (en) 2013-11-08 2015-05-14 The Board Of Regents Of The University Of Texas System Vh4 antibodies against gray matter neuron and astrocyte
US10172916B2 (en) 2013-11-15 2019-01-08 The Board Of Trustees Of The Leland Stanford Junior University Methods of treating heart failure with agonists of hypocretin receptor 2
IL245703B (en) 2013-11-20 2022-07-01 Univ Iowa Res Found Methods and preparations for the treatment of amyloid deposits
MX2016006625A (es) 2013-11-22 2016-12-02 Univ Illinois Receptores de células t humanas con alta afinidad modificados por medio de manipulación genética.
EP3074039A4 (de) 2013-11-26 2017-10-11 The Brigham and Women's Hospital, Inc. Zusammensetzungen und verfahren zur modulierung einer immunreaktion
EP3083658B1 (de) 2013-12-18 2019-05-08 President and Fellows of Harvard College Detektion gram-positiver bakterien mit crp
WO2015094527A1 (en) 2013-12-19 2015-06-25 Danisco Us Inc. Use of hydrophobins to increase gas transferin aerobic fermentation processes
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
CA2935378C (en) 2013-12-24 2023-04-18 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments
US11293929B2 (en) 2014-01-07 2022-04-05 Bioatla, Inc. Proteins targeting orthologs
JP7037884B2 (ja) 2014-01-13 2022-03-17 ベイラー リサーチ インスティテュート Ｈｐｖ及びｈｐｖ関連疾患に対する新規のワクチン
MX2016009954A (es) 2014-01-29 2017-02-23 Dana Farber Cancer Inst Inc Anticuerpos contra el dominio extracelular de muc1-c (muc1-c/ecd).
WO2015120273A1 (en) 2014-02-07 2015-08-13 The General Hospital Corporation Differential diagnosis of hepatic neoplasms
US20150232935A1 (en) 2014-02-14 2015-08-20 The General Hospital Corporation Methods for diagnosing igg4-related disease
EP3110976B1 (de) 2014-02-27 2020-05-13 Biogen MA Inc. Verfahren zur beurteilung eines pml-risikos
WO2015131099A1 (en) 2014-02-28 2015-09-03 The General Hospital Corporation Diagnosis of multiple myeloma and lymphoma
AU2015231053B2 (en) 2014-03-21 2019-04-11 Les Laboratoires Servier Compounds and their methods of use
CN111077309B (zh) 2014-04-02 2023-11-17 生化诊断系统公司 利用俘获缀合物的免疫测定
JP6789117B2 (ja) 2014-04-25 2020-11-25 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドＴｈｅ Ｂｒｉｇｈａｍ ａｎｄ Ｗｏｍｅｎ’ｓ Ｈｏｓｐｉｔａｌ， Ｉｎｃ． 免疫媒介性疾患を有する対象を処置するための組成物および方法
EP2942627A1 (de) 2014-05-05 2015-11-11 MicroBPlex, Inc. MIT VON NEULICH PROLIFERIERTEN ANTIKöRPER SEKRETIERENDEN ZELLEN NEU SYNTHETISIERTEN ANTIKÖRPERN (MENSA) ELABORIERTE MEDIEN UND VERWENDUNGEN DAVON
WO2015172083A1 (en) 2014-05-08 2015-11-12 Biogen Ma Inc. Dimethylfumarate and prodrugs for treatment of multiple sclerosis
AU2015255883A1 (en) 2014-05-08 2016-10-27 Novodiax, Inc. Direct immunohistochemistry assay
EP3143399A1 (de) 2014-05-12 2017-03-22 Biogen MA Inc. Biomarker zur vorhersage des fortschreitens von lupus und verwendungen davon
US9568404B2 (en) 2014-05-16 2017-02-14 Junyu Mai Method and apparatus for biomolecule analysis
WO2015179435A1 (en) 2014-05-19 2015-11-26 Bayer Healthcare Llc Optimized humanized monoclonal antibodies against activated protein c and uses thereof
MX2016016310A (es) 2014-06-11 2017-10-20 A Green Kathy Uso de agonistas y antagonistas vista para suprimir o aumentar la inmunidad humoral.
GB201413240D0 (en) 2014-07-25 2014-09-10 Hansa Medical Ab Method
EP4219710A3 (de) 2014-08-01 2023-08-16 Dovetail Genomics, LLC Markierung von nukleinsäuren für sequenzassemblierung
WO2016026978A1 (en) 2014-08-22 2016-02-25 Universite Nice Sophia Antipolis Methods and pharmaceutical compositions for treating drug addiction
EP3191592A1 (de) 2014-09-11 2017-07-19 Novartis AG Hemmung von prmt5 zur behandlung von erkrankungen im zusammenhang mit mtap-mangel
AU2015318018B2 (en) 2014-09-16 2017-05-11 Synermore Biologics (Suzhou) Co. Ltd. Anti-EGFR antibody and uses of same
JP6954834B2 (ja) 2014-10-06 2021-10-27 ケモセントリックス，インコーポレイティド ＣＣケモカイン受容体９（ＣＣＲ９）の阻害剤と抗α４β７インテグリン遮断抗体の併用療法
SG11201702895SA (en) 2014-10-08 2017-05-30 Novartis Ag Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
WO2016061111A1 (en) 2014-10-13 2016-04-21 Life Technologies Corporation Methods, kits & compositions for determining gene copy numbers
CA2965438A1 (en) 2014-10-24 2016-04-28 Dupont Nutrition Biosciences Aps Use of proline tolerant tripeptidyl peptidases in feed additive compositions
US20170306360A1 (en) 2014-10-24 2017-10-26 Danisco Us Inc. Method for producing alcohol by use of a tripeptidyl peptidase
US20160116466A1 (en) 2014-10-27 2016-04-28 Chembio Diagnostic Systems, Inc. Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses
US10479997B2 (en) 2014-12-01 2019-11-19 Novartis Ag Compositions and methods for diagnosis and treatment of prostate cancer
US11279974B2 (en) 2014-12-01 2022-03-22 The Broad Institute, Inc. Method for in situ determination of nucleic acid proximity
JP2018505911A (ja) 2014-12-05 2018-03-01 イミュネクスト，インコーポレーテッド 推定上のｖｉｓｔａ受容体としてのｖｓｉｇ８の同定と、ｖｉｓｔａ／ｖｓｉｇ８調節剤を産生するためのその使用
EP4242329A3 (de) 2014-12-08 2023-10-25 Berg LLC Verwendung von markern einschliesslich filamin a bei der diagnose und behandlung von prostatakrebs
KR101942955B1 (ko) 2014-12-23 2019-01-28 4디 파마 리서치 리미티드 면역 조정
KR20170091157A (ko) 2014-12-23 2017-08-08 4디 파마 리서치 리미티드 피린 폴리펩티드 및 면역 조정
AU2016219511B2 (en) 2015-02-09 2020-11-12 Research Development Foundation Engineered immunoglobulin Fc polypeptides displaying improved complement activation
GB201502306D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
GB201502305D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
WO2016134034A1 (en) 2015-02-17 2016-08-25 Dovetail Genomics Llc Nucleic acid sequence assembly
US10479825B2 (en) 2015-02-25 2019-11-19 Vanderbilt University Antibody-mediated neutralization of Marburg virus
TWI719967B (zh) 2015-03-09 2021-03-01 美商艾澤西公司 結合至ｆｌｔ３蛋白之抗體藥物結合物（ａｄｃ）
WO2016145409A1 (en) 2015-03-11 2016-09-15 The Broad Institute, Inc. Genotype and phenotype coupling
US11807896B2 (en) 2015-03-26 2023-11-07 Dovetail Genomics, Llc Physical linkage preservation in DNA storage
US9612534B2 (en) 2015-03-31 2017-04-04 Tokyo Electron Limited Exposure dose homogenization through rotation, translation, and variable processing conditions
US11279768B1 (en) 2015-04-03 2022-03-22 Precision Biologics, Inc. Anti-cancer antibodies, combination therapies, and uses thereof
US9927443B2 (en) 2015-04-10 2018-03-27 Conquerab Inc. Risk assessment for therapeutic drugs
WO2016172660A1 (en) 2015-04-23 2016-10-27 Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, Reno Fungal detection using mannan epitope
EP3091026B1 (de) 2015-05-08 2019-02-20 Centrillion Technology Holdings Corporation Disulfidvernetzte reversible terminatoren
MX2017016529A (es) 2015-06-15 2018-03-12 4D Pharma Res Ltd Composiciones que comprenden cepas bacterianas.
AU2016278067B2 (en) 2015-06-15 2022-09-22 Cj Bioscience, Inc. Compositions comprising bacterial strains
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
ES2742514T3 (es) 2015-06-15 2020-02-14 4D Pharma Res Ltd Composiciones que comprenden cepas bacterianas
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
CN107922497B (zh) 2015-06-24 2022-04-12 詹森药业有限公司 抗vista抗体和片段
BR112017028035A2 (pt) 2015-06-26 2018-08-28 Dupont Nutrition Biosci Aps aminopeptidases para hidrolisados de proteína
GB2556004A (en) 2015-07-10 2018-05-16 Univ West Virginia Markers of stroke and stroke severity
WO2017015334A1 (en) 2015-07-21 2017-01-26 Saint Louis University Compositions and methods for diagnosing and treating endometriosis-related infertility
EP3331572A4 (de) 2015-08-04 2019-05-01 CD Diagnostics, Inc. Verfahren zur erkennung von unerwünschter lokaler gewebereaktionsnekrose
CA2994209A1 (en) 2015-08-06 2017-02-09 Lia Diagnostics, Inc. Water dispersible assays
US10435457B2 (en) 2015-08-06 2019-10-08 President And Fellows Of Harvard College Microbe-binding molecules and uses thereof
WO2017031370A1 (en) 2015-08-18 2017-02-23 The Broad Institute, Inc. Methods and compositions for altering function and structure of chromatin loops and/or domains
DK3341725T3 (da) 2015-08-25 2021-09-06 Prothena Biosciences Ltd Fremgangsmåder til detektering af phosphoryleret alpha-synuklein
US10526408B2 (en) 2015-08-28 2020-01-07 Research Development Foundation Engineered antibody FC variants
WO2017040813A2 (en) 2015-09-02 2017-03-09 University Of Massachusetts Detection of gene loci with crispr arrayed repeats and/or polychromatic single guide ribonucleic acids
US11747346B2 (en) 2015-09-03 2023-09-05 Novartis Ag Biomarkers predictive of cytokine release syndrome
CA3036409C (en) 2015-09-08 2023-07-11 Erik J. Sontheimer Dnase h activity of neisseria meningitidis cas9
WO2017053567A1 (en) 2015-09-22 2017-03-30 Delta Tm Technologies Designing customized protein-specific buffer systems
WO2017059108A1 (en) 2015-09-29 2017-04-06 Htg Molecular Diagnostics, Inc. Methods for subtyping diffuse b-cell lymphoma (dlbcl)
AU2016334401A1 (en) 2015-10-10 2018-04-26 Intrexon Corporation Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12
EP3913068B1 (de) 2015-10-12 2023-08-02 Advanced Cell Diagnostics, Inc. In-situ-detektion von nukleotidvarianten bei proben mit hohem rauschen sowie zugehörige zusammensetzungen und verfahren
US9377457B1 (en) 2015-10-19 2016-06-28 Naishu Wang Progressive compression driven flow cartridge for analyte detecting strip and method
CN108368542B (zh) 2015-10-19 2022-04-08 多弗泰尔基因组学有限责任公司 用于基因组组装、单元型定相以及独立于靶标的核酸检测的方法
US20180321202A1 (en) 2015-11-06 2018-11-08 Oslo Universitetssykehus Hf Methods and devices for detecting methanol poisoning using formate oxidase
AU2016354440B2 (en) 2015-11-09 2023-09-28 The Children's Hospital Of Philadelphia Glypican 2 as a cancer marker and therapeutic target
LT3209310T (lt) 2015-11-20 2018-04-25 4D Pharma Research Limited Kompozicijos, apimančios bakterinius kamienus
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
CN109415437B (zh) 2015-12-02 2022-02-01 斯特库伯株式会社 与btn1a1免疫特异性结合的抗体和分子及其治疗用途
CN108925136B (zh) 2015-12-02 2022-02-01 斯特赛恩斯公司 特异于糖基化的btla（b和t淋巴细胞衰减因子）的抗体
JP2019507582A (ja) 2015-12-04 2019-03-22 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 免疫療法用のｓｌｃ４５ａ２ペプチド
WO2017100454A1 (en) 2015-12-09 2017-06-15 Intuitive Biosciences, Inc. Automated silver enhancement system
JOP20200228A1 (ar) 2015-12-21 2017-06-16 Novartis Ag تركيبات وطرق لخفض تعبير البروتين tau
EP3393524B1 (de) 2015-12-22 2022-04-06 The Regents of The University of Colorado, A Body Corporate Schutz von rnas vor abbau mittels manipulierter viren-rnas
WO2017139415A2 (en) 2016-02-11 2017-08-17 Qiagen Waltham, Inc. Scavenger compounds for improved sequencing-by-synthesis
WO2017139419A1 (en) 2016-02-11 2017-08-17 Qiagen Waltham, Inc. Polyphenolic additives in sequencing-by-synthesis
TWI756204B (zh) 2016-02-12 2022-03-01 比利時商楊森製藥公司 抗ｖｉｓｔａ抗體及片段、其用途及鑑定其之方法
US20200200735A9 (en) 2016-02-22 2020-06-25 Ursure, Inc. System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
EP3420108A4 (de) 2016-02-23 2019-11-06 Dovetail Genomics LLC Erzeugung von phasengesteuerten lesesätzen für die genomanordnung und haplotyp-phasenregelung
WO2017147060A1 (en) 2016-02-25 2017-08-31 Dupont Nutrition Biosciences Aps Method for producing a protein hydrolysate employing an aspergillus fumigatus tripeptidyl peptidase
US10889637B2 (en) 2016-02-26 2021-01-12 The Board Of Regents Of The University Of Texas System Methods of treating an osteolytic tumor and spinal cord injury by administering connexin (Cx) 43 hemichannel-binding antibodies
CN109476731A (zh) 2016-02-29 2019-03-15 基础医药有限公司 治疗癌症的方法
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
DK3313423T3 (da) 2016-03-04 2019-05-20 4D Pharma Plc Sammensætninger omfattende bakterielle blautia-stammer til behandling af visceral hypersensitivitet
CN109641935A (zh) 2016-03-25 2019-04-16 莫拉利达尔·瑞迪·穆拉 组合合成和生物标志物开发
CN109195991B (zh) 2016-03-29 2023-10-31 斯特库比股份有限公司 对糖基化pd-l1特异的双重功能抗体及其使用方法
EP3436480A4 (de) 2016-03-30 2019-11-27 Musc Foundation for Research Development Verfahren zur behandlung und diagnose von krebs durch targeting von glycoprotein a repetitions predominant (garp) und zur effektiven immuntherapie allein oder in kombination
US9903866B2 (en) 2016-04-05 2018-02-27 Conquerab Inc. Portable devices for detection of antibodies against therapeutic drugs
WO2017178554A1 (en) 2016-04-13 2017-10-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and kits for the rapid detection of the escherichia coli o25b-st131 clone
US9702872B1 (en) 2016-04-15 2017-07-11 Dnt Scientific Research, Llc Rapid diagnostic test device by driven flow technology
SG11201808633RA (en) 2016-04-15 2018-10-30 Immunext Inc Anti-human vista antibodies and use thereof
US9632083B1 (en) 2016-04-15 2017-04-25 Dnt Scientific Research, Llc Rapid diagnostic test device by driven flow technology
WO2017194589A1 (en) 2016-05-10 2017-11-16 Vib Vzw Inhibition of tau-mediated early synaptic dysfunction
IL262946B2 (en) 2016-05-13 2023-03-01 Dovetail Genomics Llc Retrieving long-range grip information from preserved samples
US11919971B2 (en) 2016-05-16 2024-03-05 President And Fellows Of Harvard College Aqueous biomolecule coupling on CO2-plasma-activated surfaces
JP7042755B2 (ja) 2016-06-05 2022-03-28 バーグ エルエルシー 患者層別化及び潜在的バイオマーカー同定のためのシステム及び方法
JP6908299B2 (ja) 2016-06-06 2021-07-21 メディツィニシェ ウニベルジテート ウィーン サンプル中のフラビウイルスに特異的なＩｇＭ抗体の検出方法
US9535061B1 (en) 2016-06-29 2017-01-03 Dnt Scientific Research, Llc Multi-functional rapid diagnostic test device
EP3482202A4 (de) 2016-07-11 2020-03-18 Arizona Board of Regents on behalf of Arizona State University Schweiss als biofluid zur analyse und krankheitserkennung
TW201821093A (zh) 2016-07-13 2018-06-16 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
WO2018015296A1 (en) 2016-07-20 2018-01-25 Vib Vzw Therapeutic agents for neurological and psychiatric disorders
KR20190031299A (ko) 2016-07-20 2019-03-25 주식회사 에스티큐브 글리코실화된 pd-l1에 결합하는 항체의 조합을 사용하는 암 치료 방법
WO2018045162A1 (en) 2016-09-01 2018-03-08 Biogen Ma Inc. Biomarkers predictive of primary progressive multiple sclerosis and uses thereof
US20180128828A1 (en) 2016-11-04 2018-05-10 James W. Stave Direct detection of microorganisms in patient samples by immunoassay
EP3538093B1 (de) 2016-11-09 2023-10-25 Qiagen Sciences, LLC Photoprotektive mischungen als bildgebungsreagenzien bei der sequenzierung durch synthese
IL266751B (en) 2016-11-23 2022-07-01 Chemocentryx Inc A method for the treatment of focal segmental tuberous sclerosis
WO2018100431A1 (en) 2016-11-29 2018-06-07 Genomic Vision Method for designing a set of polynucleotide sequences for analysis of specific events in a genetic region of interest
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
BR112019010002A2 (pt) 2016-12-16 2019-08-20 Merck Patent Gmbh métodos para o uso de proteína de ligação galectina-3 detectada na urina para monitoramento da gravidade e progressão da nefrite lúpica
US10656164B2 (en) 2016-12-22 2020-05-19 Qiagen Sciences, Llc Screening asymptomatic pregnant woman for preterm birth
US10935555B2 (en) 2016-12-22 2021-03-02 Qiagen Sciences, Llc Determining candidate for induction of labor
WO2018137705A1 (en) 2017-01-26 2018-08-02 Zai Lab (Shanghai) Co., Ltd. Cd47 antigen binding unit and uses thereof
EP3574114B1 (de) 2017-01-26 2022-06-29 Oklahoma Medical Research Foundation Biomarker für die krankheitsaktivität, die intensität und das auftreten von systemischem lupus erythematodes
WO2018163051A1 (en) 2017-03-06 2018-09-13 Novartis Ag Methods of treatment of cancer with reduced ubb expression
WO2018203145A1 (en) 2017-05-03 2018-11-08 Oslo Universitetssykehus Hf Systems and methods for monitoring biological fluids
KR20200019882A (ko) 2017-05-22 2020-02-25 4디 파마 리서치 리미티드 세균 균주를 포함하는 조성물
MA41708A (fr) 2017-05-24 2020-04-08 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
CA3065301A1 (en) 2017-05-31 2018-12-06 Stcube & Co., Inc. Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof
CN111051346A (zh) 2017-05-31 2020-04-21 斯特库伯株式会社 使用免疫特异性结合btn1a1的抗体和分子治疗癌症的方法
US11542331B2 (en) 2017-06-06 2023-01-03 Stcube & Co., Inc. Methods of treating cancer using antibodies and molecules that bind to BTN1A1 or BTN1A1-ligands
ES2823053T3 (es) 2017-06-14 2021-05-07 4D Pharma Res Ltd Composiciones que comprenden una cepa bacteriana del género Megasphaera y usos de las mismas
LT3638271T (lt) 2017-06-14 2021-01-11 4D Pharma Research Limited Kompozicijos, apimančios bakterines padermes
US9784733B1 (en) 2017-06-22 2017-10-10 Dnt Scientific Research, Llc Rapid diagnostic test device by driven flow technology
WO2019016772A2 (en) 2017-07-21 2019-01-24 Novartis Ag COMPOSITIONS AND METHODS FOR TREATING CANCER
ES2953011T3 (es) 2017-07-21 2023-11-07 Fundacio Hospital Univ Vall Dhebron Institut De Recerca Agrina como marcador de cáncer de endometrio
US9823244B1 (en) 2017-07-31 2017-11-21 Dnt Scientific Research, Llc Digital progressive compression driven flow cartridge for analyte detecting device and method
BR112020003533A2 (pt) 2017-08-25 2020-11-17 Five Prime Therapeutics, Inc. anticorpos b7-h4 e métodos de uso dos mesmos
JP7145895B2 (ja) 2017-09-01 2022-10-03 四川科倫博泰生物医薬股▲フン▼有限公司 組換え二重特異性抗体
CA3074291A1 (en) 2017-09-05 2019-03-14 GLAdiator Biosciences, Inc. Delivery of payloads to stem cells
WO2019055825A1 (en) 2017-09-15 2019-03-21 The Regents Of The University Of California INHIBITION OF AMINOACYLASE 3 (AA3) IN THE TREATMENT OF CANCER
EP3694545A4 (de) 2017-10-11 2021-12-01 Board Of Regents, The University Of Texas System Menschliche pd-l1-antikörper und verfahren zu ihrer verwendung
CA3078809A1 (en) 2017-10-11 2019-04-18 Chemocentryx, Inc. Treatment of focal segmental glomerulosclerosis with ccr2 antagonists
JP2021502125A (ja) 2017-11-09 2021-01-28 ピンテオン セラピューティクス インコーポレイテッド ヒト化コンホメーション特異的リン酸化タウ抗体の作製および使用のための方法および組成物
CN109870581B (zh) 2017-12-04 2021-05-04 厦门万泰凯瑞生物技术有限公司 一种定量检测HBsAg的试剂盒及方法
CA3085324A1 (en) 2017-12-15 2019-06-20 Syngenta Participations Ag Non-antibody ligands for detecting target proteins
EP3735589A2 (de) 2018-01-05 2020-11-11 Vanderbilt University Antikörpervermittelte neutralisierung des chikungunya-virus
WO2019155041A1 (en) 2018-02-12 2019-08-15 Vib Vzw Gβγ COMPLEX ANTIBODIES AND USES THEREOF
WO2019165217A1 (en) 2018-02-22 2019-08-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cd153 and/or cd30 in infection
AU2019228600A1 (en) 2018-03-02 2020-09-24 Five Prime Therapeutics, Inc. B7-H4 antibodies and methods of use thereof
WO2019173703A1 (en) 2018-03-08 2019-09-12 Meso Scale Technologies, Llc. Genetic marker and/or biomarkers for traumatic brain injury, and ultrasensitive assays for biomarkers of traumatic brain injury
US20210214445A1 (en) 2018-03-23 2021-07-15 Board Of Regents, The University Of Texas System Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor
EP3775273B1 (de) 2018-04-09 2023-01-18 Advanced Cell Diagnostics, Inc. Verfahren zur weiteren erhöhung der signalverstärkung für den in-situ-nachweis von nukleinsäuren
JP7328324B2 (ja) 2018-04-24 2023-08-16 アンプソース・バイオファーマ・シャンハイ・インコーポレイテッド Ｔｉｍ－３に対する抗体およびその使用
US20210123016A1 (en) 2018-05-02 2021-04-29 Novartis Ag Regulators of human pluripotent stem cells and uses thereof
WO2019237119A1 (en) 2018-06-08 2019-12-12 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services New compositions and detection methods for onchocerca volvulus infection
TW202016144A (zh) 2018-06-21 2020-05-01 日商第一三共股份有限公司 包括cd3抗原結合片段之組成物及其用途
AU2019301138A1 (en) 2018-07-11 2021-02-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Monoclonal antibody for the detection of the antiretroviral drug emtricitabine (FTC, 2',3'-dideoxy-5-fluoro-3'-thiacytidine)
CA3107352A1 (en) 2018-07-23 2020-01-30 Enclear Therapies, Inc. Methods of treating neurological disorders
CN113164563A (zh) 2018-07-23 2021-07-23 因柯利尔疗法公司 神经性病症的治疗方法
TW202019480A (zh) 2018-09-13 2020-06-01 美國德州系統大學評議委員會 新穎lilrb4抗體及其用途
CA3113676A1 (en) 2018-09-21 2020-03-26 President And Fellows Of Harvard College Methods and compositions for treating diabetes, and methods for enriching mrna coding for secreted proteins
US20220048940A1 (en) 2018-09-28 2022-02-17 Centrillion Technology Holdings Corporation Disulfide-linked reversible terminators
EA202191033A1 (ru) 2018-10-15 2021-12-21 Юниверсити Оф Массачусетс Программируемое редактирование оснований днк посредством слитых белков nme2cas9-дезаминаза
WO2020081204A1 (en) 2018-10-18 2020-04-23 Oklahoma Medical Research Foundation Biomarkers for a systemic lupus erythematosus (sle) disease activity immune index that characterizes disease activity
US20210403552A1 (en) 2018-10-22 2021-12-30 Shanghai GenBase Biotechnology Co., Ltd. Anti-cldn18.2 antibody and uses thereof
EP3870614A1 (de) 2018-10-23 2021-09-01 GlyCardial Diagnostics, S.L. Antikörper spezifisch für glykosyliertes apoj und verwendungen davon
US10451613B1 (en) 2018-11-09 2019-10-22 Dnt Scientific Research, Llc Rapid diagnostic test device and sampling method using driven flow technology
CN111196851B (zh) 2018-11-20 2021-11-16 厦门万泰凯瑞生物技术有限公司 针对人抗缪勒管激素的特异性抗体及其应用
US20220089776A1 (en) 2018-11-28 2022-03-24 Oregon Health & Science University Therapeutic factor xii antibody
AU2019389175A1 (en) 2018-11-30 2021-06-10 Caris Mpi, Inc. Next-generation molecular profiling
CN113166246A (zh) 2018-12-28 2021-07-23 四川科伦博泰生物医药股份有限公司 一种抗体及其用途
EP3914734B1 (de) 2019-01-25 2024-03-13 President and Fellows of Harvard College Zusammensetzungen und verfahren zur sequenzierung von nukleinsäuren
US11300576B2 (en) 2019-01-29 2022-04-12 Arizona Board Of Regents On Behalf Of Arizona State University DARPin reagents that distinguish Alzheimer's disease and Parkinson's disease samples
WO2020168162A1 (en) 2019-02-15 2020-08-20 Bio-Techne Corporation Methods for multiplex detection of nucleic acids by in situ hybridization
JP2022526671A (ja) 2019-04-11 2022-05-25 エンクリアー セラピーズ， インク． 脳脊髄液の改善の方法ならびにそのためのデバイスおよびシステム
JP2022528595A (ja) 2019-04-16 2022-06-15 シチュアン ケルン－バイオテック バイオファーマシューティカル カンパニー リミテッド 抗ＦＸＩ／ＦＸＩａ抗体及びその使用
AU2020265250A1 (en) 2019-04-30 2021-11-18 Larimar Therapeutics, Inc. Frataxin-sensitive markers for determining effectiveness of frataxin replacement therapy
US11549943B2 (en) 2019-05-31 2023-01-10 International Business Machines Corporation Multiplexed lateral flow assay device
US11906515B2 (en) * 2019-05-31 2024-02-20 International Business Machines Corporation Multiplexed lateral flow assay device
US11878297B2 (en) 2019-06-04 2024-01-23 Abbott Toxicology Limited Fluid specimen testing
DE102019117289A1 (de) 2019-06-27 2020-12-31 Katja Werner Trägermaterial, Kitsystem und Verfahren für biologische Assays
DE102019117413A1 (de) * 2019-06-27 2020-12-31 Testo SE & Co. KGaA Fließtest-Einheit, Set und Verwendung einer Fließtest-Einheit zur Durchführung einer Nachweisreaktion
AU2020317009A1 (en) 2019-07-19 2022-02-03 The Board Of Trustees Of The Leland Stanford Junior University Chimeric antigen receptors containing Glypican 2 binding domains
KR20220038415A (ko) 2019-07-26 2022-03-28 벤더르빌트 유니버시티 엔테로바이러스 d68에 대한 인간 모노클로날 항체
WO2021051390A1 (zh) 2019-09-20 2021-03-25 上海吉倍生物技术有限公司 靶向bcma的抗体及嵌合抗原受体
WO2021062323A1 (en) 2019-09-26 2021-04-01 Stcube & Co. Antibodies specific to glycosylated ctla-4 and methods of use thereof
CN114206931A (zh) 2019-09-30 2022-03-18 四川科伦博泰生物医药股份有限公司 抗pd-1抗体及其用途
JP2022552282A (ja) 2019-10-09 2022-12-15 エスティーキューブ アンド カンパニー グリコシル化ｌａｇ３に対して特異的な抗体およびその使用方法
WO2021092004A1 (en) 2019-11-05 2021-05-14 Meso Scale Technologies, Llc. Methods and kits for quantitating radiation exposure
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
US20230021837A1 (en) 2019-11-26 2023-01-26 Meso Scale Technologies, Llc. Methods and kits for detecting autoimmune diseases
EP4069865A4 (de) 2019-12-02 2023-12-20 Caris MPI, Inc. Platinresistenztest für pan-krebs
EP4073246A4 (de) 2019-12-12 2023-12-06 President And Fellows Of Harvard College Zusammensetzungen und verfahren zur lichtgerichteten biomolekularen barcodierung
MX2022004919A (es) 2019-12-13 2022-05-16 Sichuan Kelun Biotech Biopharmaceutical Co Ltd Anticuerpo anti-linfopoyetina estromal timica (tslp) y sus usos.
CA3164996A1 (en) 2019-12-20 2021-06-14 Novarock Biotherapeutics, Ltd. Anti-interleukin-23 p19 antibodies and methods of use thereof
EP3842452A1 (de) 2019-12-26 2021-06-30 Universitat Autònoma de Barcelona Gerüstproteine und therapeutische nanokonjugate auf nidogenbasis
CN113061165A (zh) 2020-01-02 2021-07-02 厦门大学 EB病毒BNLF2b基因编码多肽及其检测用途
WO2021156490A2 (en) 2020-02-06 2021-08-12 Vib Vzw Corona virus binders
AU2021220847A1 (en) 2020-02-11 2022-09-01 Vanderbilt University Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV- 2)
CA3168337A1 (en) 2020-02-17 2021-08-26 Marie-Andree Forget Methods for expansion of tumor infiltrating lymphocytes and use thereof
CN115698047A (zh) 2020-02-25 2023-02-03 非营利性组织佛兰芒综合大学生物技术研究所 富含亮氨酸的重复激酶2变构调节剂
MX2022011892A (es) 2020-03-26 2022-10-18 Univ Vanderbilt Anticuerpos monoclonales humanos dirigidos contra el coronavirus 2 del sindrome respiratorio agudo grave (sars-cov-2).
WO2021195385A1 (en) 2020-03-26 2021-09-30 Vanderbilt University HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-GoV-2)
TW202203916A (zh) 2020-03-31 2022-02-01 美商卡默森屈有限公司 使用ｃｃｒ９抑制劑及抗ｉｌ—２３阻斷抗體治療發炎性腸道疾病的組成物及方法
WO2021216728A1 (en) 2020-04-22 2021-10-28 President And Fellows Of Harvard College Isothermal methods, compositions, kits, and systems for detecting nucleic acids
US20210349104A1 (en) 2020-05-01 2021-11-11 Meso Scale Technologies, Llc. Viral serology assays
JP7407973B2 (ja) 2020-05-15 2024-01-04 シチュアン ケルン－バイオテック バイオファーマシューティカル カンパニー リミテッド 抗体薬物複合体、その調製方法、およびその使用
EP3939999A1 (de) 2020-07-14 2022-01-19 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Antikörper zur neutralisierung der interleukin-11-rezeptor-alpha-unterheinheit (il11ra) und verwendungen davon
WO2022047359A1 (en) 2020-08-31 2022-03-03 Berg Llc Protein biomarkers for pancreatic cancer
WO2022051591A2 (en) 2020-09-04 2022-03-10 Novarock Biotherapeutics, Ltd. Nectin-4 antibodies and uses thereof
GB202105804D0 (en) 2020-11-20 2021-06-09 Univ Cape Town Use of microvirin in the identification of mycobacterium tuberculosis mannose-capped lipoarabinomannan
CN117460543A (zh) 2020-12-04 2024-01-26 田纳西大学研究基金会 用于诊断淀粉样蛋白病的方法
EP4253413A1 (de) 2020-12-31 2023-10-04 Nona Biosciences (Suzhou) Co., Ltd. Menschliches lifr-antigen-bindendes protein, herstellungsverfahren dafür und anwendung davon
GB2603166A (en) 2021-01-29 2022-08-03 Thelper As Therapeutic and Diagnostic Agents and Uses Thereof
CA3206117A1 (en) 2021-02-09 2022-08-18 Medilink Therapeutics (Suzhou) Co., Ltd. Bioactive substance conjugate, preparation method therefor and use thereof
IL305318A (en) 2021-02-19 2023-10-01 Vib Vzw Cation-independent mannose-6-phosphate receptor binders
WO2022183502A1 (zh) 2021-03-05 2022-09-09 上海吉倍生物技术有限公司 抗cldn6抗体及其用途
EP4304660A1 (de) 2021-03-08 2024-01-17 ImmunoGen, Inc. Verfahren zur erhöhung der wirksamkeit von auf adam9 abzielenden immunkonjugaten zur behandlung von krebs
JP2024508597A (ja) 2021-03-09 2024-02-28 四川科倫博泰生物医薬股▲フン▼有限公司 Ｒｏｒ１結合タンパク質及びその用途
WO2022216841A1 (en) 2021-04-06 2022-10-13 Berg Llc Protein markers for estrogen receptor (er)-positive luminal a(la)-like and luminal b1 (lb1)-like breast cancer
CA3214821A1 (en) 2021-04-06 2022-10-13 Guisong WANG Protein markers for estrogen receptor (er)-positive-like and estrogen receptor (er)-negative-like breast cancer
EP4320443A1 (de) 2021-04-06 2024-02-14 BPGbio, Inc. Proteinmarker zur prognose der brustkrebsprogression
CA3215979A1 (en) 2021-04-19 2022-10-27 Ghassan SAED Methods for detecting or treating endometrial and ovarian hyperproliferative disorders
WO2022246215A1 (en) 2021-05-21 2022-11-24 Meso Scale Technologies, Llc. Viral strain serology assays
CA3223081A1 (en) 2021-07-15 2023-01-19 Samir Mitragotri Compositions and methods relating to cells with adhered particles
AU2022315559A1 (en) 2021-07-23 2024-02-15 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Biomarkers for endometrial cancer
WO2023016828A2 (en) 2021-07-30 2023-02-16 Vib Vzw Cation-independent mannose-6-phosphate receptor binders for targeted protein degradation
WO2023081070A1 (en) 2021-11-02 2023-05-11 University Of Massachusetts Nme2Cas9 INLAID DOMAIN FUSION PROTEINS
TW202323301A (zh) 2021-11-19 2023-06-16 英商米羅比奧有限公司 經工程改造之ｐｄ－１抗體及其用途
GB202201137D0 (en) 2022-01-28 2022-03-16 Thelper As Therapeutic and diagnostic agents and uses thereof
EP4238988A1 (de) 2022-03-01 2023-09-06 Consejo Superior De Investigaciones Científicas Antikörper gegen sars-cov-2 und verwendungen davon
WO2023192976A1 (en) 2022-04-01 2023-10-05 Board Of Regents, The University Of Texas System Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor
GB202204813D0 (en) 2022-04-01 2022-05-18 Bradcode Ltd Human monoclonal antibodies and methods of use thereof
US20230357851A1 (en) 2022-04-06 2023-11-09 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring frataxin-replacement therapy
WO2023196866A1 (en) 2022-04-06 2023-10-12 Mirobio Limited Engineered cd200r antibodies and uses thereof
WO2023240201A1 (en) 2022-06-08 2023-12-14 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring progression and treatment of leigh syndrome
WO2023239710A1 (en) 2022-06-08 2023-12-14 Onkure, Inc. Benzopyrimidin-4(3h)-ones as pi3k inhibitors
WO2023239940A1 (en) 2022-06-10 2023-12-14 Research Development Foundation Engineered fcriib selective igg1 fc variants and uses thereof
WO2023245184A1 (en) 2022-06-17 2023-12-21 Meso Scale Technologies, Llc. Viral strain serology assays
WO2024028794A1 (en) 2022-08-02 2024-02-08 Temple Therapeutics BV Methods for treating endometrial and ovarian hyperproliferative disorders
WO2024040020A1 (en) 2022-08-15 2024-02-22 Absci Corporation Quantitative affinity activity specific cell enrichment
WO2024038160A1 (en) 2022-08-18 2024-02-22 Vib Vzw Means and methods to modulate neuron excitability
WO2024054469A1 (en) 2022-09-08 2024-03-14 Onkure, Inc. Isoquinolones as pi3k inhibitors
WO2024064024A1 (en) 2022-09-19 2024-03-28 Onkure, Inc. ((4-oxo-3,4-dihydroquinazolin-8-yl)methyl)amine derivatives as p13k inhibitors for the treatment of cancer
WO2024064002A1 (en) 2022-09-20 2024-03-28 Onkure, Inc. Hdac inhibitor oki-179 for the treatment of cancers resulting from a mapk pathway mutation
WO2024064904A1 (en) 2022-09-23 2024-03-28 Meso Scale Technologies, Llc. Orthopoxvirus serology assays
WO2024068744A1 (en) 2022-09-27 2024-04-04 Vib Vzw Antivirals against human parainfluenza virus

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3811840A (en) * 1969-04-01 1974-05-21 Miles Lab Test device for detecting low concentrations of substances in fluids
US4190496A (en) * 1971-05-14 1980-02-26 Syva Company Homogeneous enzyme assay for antibodies
CA983358A (en) * 1971-09-08 1976-02-10 Kenneth D. Bagshawe Performance of chemical or biological reactions
JPS4939720A (de) * 1972-08-26 1974-04-13
DE2436598C2 (de) * 1974-07-30 1983-04-07 Boehringer Mannheim Gmbh, 6800 Mannheim Stabiler Teststreifen zum Nachweis von Inhaltsstoffen in Flüssigkeiten
SE388694B (sv) * 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
US4094647A (en) * 1976-07-02 1978-06-13 Thyroid Diagnostics, Inc. Test device
CA1095819A (en) * 1977-01-14 1981-02-17 Eastman Kodak Company Element for analysis of liquids
IL51354A (en) * 1977-01-28 1979-07-25 Ames Yissum Ltd Assay method for the quantitative determination of a hapten in aqueous solution
US4160008A (en) * 1978-01-26 1979-07-03 Miles Laboratories, Inc. Multilayered test device for determining the presence of a liquid sample component, and method of use
US4226978A (en) * 1978-03-13 1980-10-07 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled aminoglycoside antibiotics and intermediates in their preparation
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
AU531777B2 (en) * 1978-04-05 1983-09-08 Syva Co. Label/solid conjugate immunoassay system
US4258001A (en) * 1978-12-27 1981-03-24 Eastman Kodak Company Element, structure and method for the analysis or transport of liquids
US4301139A (en) * 1979-06-21 1981-11-17 Ames-Yissum Ltd. Multilayer column chromatography specific binding assay method, test device and test kit
US4299916A (en) * 1979-12-26 1981-11-10 Syva Company Preferential signal production on a surface in immunoassays

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EP0046004A1 (de) 1982-02-17
US4366241A (en) 1982-12-28
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US4366241B1 (de) 1988-10-18
JP2505979B2 (ja) 1996-06-12
EP0046004B1 (de) 1984-11-28
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