DE3167436D1 - Concentrating zone method in heterogeneous immunoassays - Google Patents

Concentrating zone method in heterogeneous immunoassays

Info

Publication number: DE3167436D1
Authority: DE; Germany
Prior art keywords: zone; signal; immunosorbing; mip; zone method
Prior art date: 1980-08-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

DE8181302826T

Other languages

English (en)

Inventor

Henry Kork Tom

Gerald Leroy Rowley

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Siemens Healthcare Diagnostics GmbH Germany

Original Assignee

Syva Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-08-07

Filing date

1981-06-23

Publication date

1985-01-10

1981-06-23 Application filed by Syva Co filed Critical Syva Co

1985-01-10 Application granted granted Critical

1985-01-10 Publication of DE3167436D1 publication Critical patent/DE3167436D1/de

Status Expired legal-status Critical Current

Links

238000003018 immunoassay Methods 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
239000007788 liquid Substances 0.000 abstract 2
239000012491 analyte Substances 0.000 abstract 1
230000001900 immune effect Effects 0.000 abstract 1
239000003446 ligand Substances 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures

DE8181302826T 1980-08-07 1981-06-23 Concentrating zone method in heterogeneous immunoassays Expired DE3167436D1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/176,177 US4366241A (en)	1980-08-07	1980-08-07	Concentrating zone method in heterogeneous immunoassays

Publications (1)

Publication Number	Publication Date
DE3167436D1 true DE3167436D1 (en)	1985-01-10

Family

ID=22643311

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE8181302826T Expired DE3167436D1 (en)	1980-08-07	1981-06-23	Concentrating zone method in heterogeneous immunoassays

Country Status (9)

Country	Link
US (1)	US4366241A (de)
EP (1)	EP0046004B1 (de)
JP (3)	JPS5763454A (de)
AT (1)	ATE10548T1 (de)
CA (1)	CA1174595A (de)
DE (1)	DE3167436D1 (de)
HK (1)	HK15887A (de)
MY (1)	MY8700300A (de)
SG (1)	SG89186G (de)

Families Citing this family (1192)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5622871A (en) *	1987-04-27	1997-04-22	Unilever Patent Holdings B.V.	Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
US6630328B2 (en)	1909-07-15	2003-10-07	Genencor International, Inc.	Increasing production of proteins in gram-positive microorganisms
US4849338A (en) *	1982-07-16	1989-07-18	Syntex (U.S.A.) Inc.	Simultaneous calibration heterogeneous immunoassay
US4299916A (en) *	1979-12-26	1981-11-10	Syva Company	Preferential signal production on a surface in immunoassays
US4843000A (en) *	1979-12-26	1989-06-27	Syntex (U.S.A.) Inc.	Simultaneous calibration heterogeneous immunoassay
US4540659A (en) *	1981-04-17	1985-09-10	Syva Company	Simultaneous calibration heterogeneous immunoassay
US5156953A (en) *	1979-12-26	1992-10-20	Syntex (U.S.A.) Inc.	Simultaneous calibration heterogeneous immunoassay
US5432057A (en) *	1979-12-26	1995-07-11	Syva Company	Simultaneous calibration heterogeneous immunoassay
US4533629A (en) *	1981-04-17	1985-08-06	Syva Company	Simultaneous calibration heterogeneous immunoassay
JPS5782766A (en) *	1980-11-11	1982-05-24	Konishiroku Photo Ind Co Ltd	Amynological measuring element
US4517288A (en) *	1981-01-23	1985-05-14	American Hospital Supply Corp.	Solid phase system for ligand assay
US4752562A (en) *	1981-01-23	1988-06-21	Baxter Travenol Laboratories, Inc.	Detection of serum antibody and surface antigen by radial partition immunoassay
US4774174A (en) *	1981-01-23	1988-09-27	Baxter Travenol Laboratories, Inc.	Solid phase system for ligand assay
US4786606A (en) *	1981-01-23	1988-11-22	Baxter Travenol Laboratories, Inc.	Solid phase system for ligand assay
US4442204A (en) *	1981-04-10	1984-04-10	Miles Laboratories, Inc.	Homogeneous specific binding assay device and preformed complex method
US4447526A (en) *	1981-04-20	1984-05-08	Miles Laboratories, Inc.	Homogeneous specific binding assay with carrier matrix incorporating specific binding partner
US5624814A (en) *	1981-08-20	1997-04-29	Becton Dickinson And Company	Culture medium and method for culturing body fluids containing antibiotics
CA1209889A (en) *	1981-09-18	1986-08-19	Litai Weng	Homogeneous assay on a non-porous surface
US4463090A (en) *	1981-09-30	1984-07-31	Harris Curtis C	Cascade amplification enzyme immunoassay
US5073484A (en) *	1982-03-09	1991-12-17	Bio-Metric Systems, Inc.	Quantitative analysis apparatus and method
US4654300A (en) *	1982-04-02	1987-03-31	Syntex (U.S.A.) Inc.	Fluorescent microbead quenching assay
IL68506A (en) *	1982-05-04	1988-06-30	Syva Co	Simultaneous calibration heterogeneous immunoassay method and device and kit for use therein
CA1228811A (en)	1983-05-05	1987-11-03	Robert G. Pergolizzi	Assay method utilizing polynucleotide sequences
USRE34405E (en) *	1983-08-01	1993-10-12	Abbott Laboratories	Determination of analytes in particle-containing medium
US4552839A (en) *	1983-08-01	1985-11-12	Syntex (U.S.A.) Inc.	Determination of analytes in particle-containing medium
US4522786A (en) *	1983-08-10	1985-06-11	E. I. Du Pont De Nemours And Company	Multilayered test device for detecting analytes in liquid test samples
DE3484505D1 (de) *	1983-12-19	1991-05-29	Daiichi Pure Chemicals Co Ltd	Immuntest.
SE446229B (sv) *	1984-01-25	1986-08-18	Syn Tek Ab	Sett och anordning for detektering av en analyt i ett prov som bringas att passera en yta till vilken bundits ett emne med specifik affinitet till analyten
US4791056A (en) *	1984-03-27	1988-12-13	Syntex (U.S.A.) Inc.	Calibration device for heterogeneous immunoassay
US4632901A (en) *	1984-05-11	1986-12-30	Hybritech Incorporated	Method and apparatus for immunoassays
US4624929A (en) *	1984-12-03	1986-11-25	Syntex (U.S.A.) Inc.	Sample collector and assay device and method for its use
SE458643B (sv) *	1984-12-07	1989-04-17	Pharmacia Ab	Anordning med kolonnelement uppdelat i provparti och referenspatri
DE3445816C1 (de) *	1984-12-15	1986-06-12	Behringwerke Ag, 3550 Marburg	Flaechenfoermiges diagnostisches Mittel
DE3586951T2 (de) *	1984-12-20	1993-04-29	Nycomed Pharma As	Festphasendiffusionstextverfahren.
US5958790A (en) *	1984-12-20	1999-09-28	Nycomed Imaging As	Solid phase transverse diffusion assay
US4740468A (en) *	1985-02-14	1988-04-26	Syntex (U.S.A.) Inc.	Concentrating immunochemical test device and method
EP0216841A1 (de) *	1985-03-18	1987-04-08	Btg International Limited	Antigenaktives protein und seine anwendung zur diagnose von gonorrhoea
US5879881A (en) *	1985-04-04	1999-03-09	Hybritech, Incorporated	Solid phase system for use in ligand-receptor assays
US4824784A (en) *	1985-04-08	1989-04-25	Hygeia Sciences, Incorporated	Chromogenic solution for immunoassay
US4623461A (en) *	1985-05-31	1986-11-18	Murex Corporation	Transverse flow diagnostic device
US4670381A (en) *	1985-07-19	1987-06-02	Eastman Kodak Company	Heterogeneous immunoassay utilizing horizontal separation in an analytical element
US4806311A (en) *	1985-08-28	1989-02-21	Miles Inc.	Multizone analytical element having labeled reagent concentration zone
US4900663A (en) *	1985-09-13	1990-02-13	Environmental Diagnostics, Inc.	Test kit for determining the presence of organic materials and method of utilizing same
US5240844A (en) *	1985-09-13	1993-08-31	Wie Siong I	Test kit for determining the presence of organic materials and method of utilizing same
US4675300A (en) *	1985-09-18	1987-06-23	The Board Of Trustees Of The Leland Stanford Junior University	Laser-excitation fluorescence detection electrokinetic separation
TW203120B (de) *	1985-10-04	1993-04-01	Abbott Lab
US5501949A (en) *	1985-12-10	1996-03-26	Murex Diagnostics Corporation	Particle bound binding component immunoassay
DE3543749A1 (de) *	1985-12-11	1987-06-19	Boehringer Mannheim Gmbh	Verfahren zur herstellung eines reagenzpapieres fuer die immunologische analyse
US4868108A (en) *	1985-12-12	1989-09-19	Hygeia Sciences, Incorporated	Multiple-antibody detection of antigen
EP0250557A4 (de) *	1985-12-12	1990-01-11	Dennison Mfg Co	Bestimmung von testsubstanzen.
US5273877A (en) *	1985-12-24	1993-12-28	Massachusetts Institute Of Technology	Non-histological cell type determination
US4916056A (en) *	1986-02-18	1990-04-10	Abbott Laboratories	Solid-phase analytical device and method for using same
US5160701A (en) *	1986-02-18	1992-11-03	Abbott Laboratories	Solid-phase analytical device and method for using same
JPS62231168A (ja) *	1986-03-21	1987-10-09	ハイブリテツク・インコ−ポレイテツド	アナライト−レセプタ−分析用内部標準を設けるための改良法
US5190864A (en) *	1986-04-15	1993-03-02	Northeastern University	Enzyme amplification by using free enzyme to release enzyme from an immobilized enzyme material
US4937188A (en) *	1986-04-15	1990-06-26	Northeastern University	Enzyme activity amplification method for increasing assay sensitivity
US4851210A (en) *	1986-05-22	1989-07-25	Genelabs Incorporated	Blood typing device
AU7033787A (en) *	1986-05-30	1987-12-22	Quidel	Enzyme immunoassay device
AU602694B2 (en) *	1986-06-09	1990-10-25	Ortho Diagnostic Systems Inc.	Improved colloidal gold membrane assay
CA1283447C (en) *	1986-06-20	1991-04-23	John W. Parce	Zero volume electrochemical cell
US4915812A (en) *	1986-06-20	1990-04-10	Molecular Devices Corporation	Zero volume cell
US5120504A (en) *	1986-07-14	1992-06-09	Hybritech Incorporated	Apparatus for immunoassays with vent chennels in the container side wall
US4935346A (en)	1986-08-13	1990-06-19	Lifescan, Inc.	Minimum procedure system for the determination of analytes
US4790979A (en) *	1986-08-29	1988-12-13	Technimed Corporation	Test strip and fixture
US4959307A (en) *	1986-09-05	1990-09-25	Syntex (U.S.A.) Inc.	Immunoseparating strip
US5260194A (en) *	1986-09-05	1993-11-09	Syntex (U.S.A.) Inc.	Immunoseparating strip
US5085988A (en) *	1986-09-05	1992-02-04	Syntex (U.S.A.) Inc.	Immunoseparating strip
US5260193A (en) *	1986-09-05	1993-11-09	Syntex (U.S.A.) Inc.	Immunoseparating strip
US4963468A (en) *	1986-09-05	1990-10-16	Syntex (U.S.A.) Inc.	Immunoseparating strip
US20010023075A1 (en) *	1992-04-03	2001-09-20	Siu-Yin Wong	A immunodiagnositc device having a dessicant incorporated therein
US5763262A (en) *	1986-09-18	1998-06-09	Quidel Corporation	Immunodiagnostic device
DE3636060C3 (de) *	1986-10-23	1994-04-07	Behringwerke Ag	Bioaffine poröse Festphase, Verfahren zu deren Herstellung und ihre Verwendung
ES2059339T3 (es) *	1986-10-23	1994-11-16	Behringwerke Ag	Fases solidas porosas bioafines, un procedimiento para la preparacion de fases solidas porosas bioafines y su utilizacion.
EP0271204A3 (de) *	1986-11-07	1989-10-25	Syntex (U.S.A.) Inc.	Immunochromatographische Methode und Vorrichtung
US5030558A (en) *	1986-11-07	1991-07-09	Syntex (U.S.A.) Inc.	Qualitative immunochromatographic method and device
JPH01501819A (ja) *	1986-11-13	1989-06-22	ジェネ　ラブス，インコーポレイティド	血液親和性診断方法
US4978502A (en) *	1987-01-05	1990-12-18	Dole Associates, Inc.	Immunoassay or diagnostic device and method of manufacture
US4769333A (en) *	1987-01-05	1988-09-06	Dole Associates, Inc.	Personal diagnostic kit
US4859603A (en) *	1987-01-05	1989-08-22	Dole Associates, Inc.	Personal diagnostic kit
US5079142A (en) *	1987-01-23	1992-01-07	Synbiotics Corporation	Orthogonal flow immunoassays and devices
US4920046A (en) *	1987-02-20	1990-04-24	Becton, Dickinson And Company	Process, test device, and test kit for a rapid assay having a visible readout
US4833087A (en) *	1987-02-27	1989-05-23	Eastman Kodak Company	Disposable container configured to produce uniform signal
US5250412A (en) *	1987-03-23	1993-10-05	Diamedix Corporation	Swab device and method for collecting and analyzing a sample
US4849340A (en) *	1987-04-03	1989-07-18	Cardiovascular Diagnostics, Inc.	Reaction system element and method for performing prothrombin time assay
US4857453A (en) *	1987-04-07	1989-08-15	Syntex (U.S.A.) Inc.	Immunoassay device
EP1248112A3 (de) *	1987-04-27	2004-08-25	Inverness Medical Switzerland GmbH	Immunochromatographische Spezifischebindungsassayvorrichtung
US4973549A (en) *	1987-06-22	1990-11-27	Chemtrak Corporation	Quantitative diagnostic assay employing signal producing agent bound to support and measuring migration distance of detectable signal
US5120643A (en)	1987-07-13	1992-06-09	Abbott Laboratories	Process for immunochromatography with colloidal particles
WO1989001626A1 (en) *	1987-08-19	1989-02-23	Flemming Gmbh	Process and device for detecting an antigen or antibody in a liquid test specimen
US4981786A (en) *	1987-09-04	1991-01-01	Syntex (U.S.A.) Inc.	Multiple port assay device
DE3730059A1 (de) *	1987-09-08	1989-03-30	Behringwerke Ag	Verfahren zur bestimmung von "loeslichem" fibrin
US4956302A (en) *	1987-09-11	1990-09-11	Abbott Laboratories	Lateral flow chromatographic binding assay device
ES2039533T3 (es) *	1987-09-11	1993-10-01	Abbott Laboratories	Metodos y dispositivos para llevar a cabo ensayos de union especifica.
US5006464A (en) *	1987-10-01	1991-04-09	E-Y Laboratories, Inc.	Directed flow diagnostic device and method
FR2621393B1 (fr) *	1987-10-05	1991-12-13	Toledano Jacques	Dispositif de detection immunoenzymatique de substances a partir d'une goutte de sang ou de liquide provenant d'un quelconque milieu biologique
US4999163A (en) *	1987-10-29	1991-03-12	Hygeia Sciences, Inc.	Disposable, pre-packaged device for conducting immunoassay procedures
US4943525A (en) *	1987-11-02	1990-07-24	Bioventures, Inc.	Simultaneous immunoassay for the determination of antigens and antibodies
US5256372A (en) *	1987-11-06	1993-10-26	Idexx Corporation	Dipstick test device including a removable filter assembly
US4818677A (en) *	1987-12-03	1989-04-04	Monoclonal Antibodies, Inc.	Membrane assay using focused sample application
JPH0630628B2 (ja) *	1987-12-16	1994-04-27	キング醸造株式会社	生細胞数及び活力の測定方法
US5206177A (en) *	1988-01-21	1993-04-27	Boehringer Mannheim Corporation	Apparatus for determining an analyte and method therefor
US4963325A (en) *	1988-05-06	1990-10-16	Hygeia Sciences, Inc.	Swab expressor immunoassay device
US5137804A (en) *	1988-05-10	1992-08-11	E. I. Du Pont De Nemours And Company	Assay device and immunoassay
US5374524A (en) *	1988-05-10	1994-12-20	E. I. Du Pont De Nemours And Company	Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5039607A (en) *	1988-05-17	1991-08-13	Syntex (U.S.A.) Inc.	Method for immunochromatographic analysis
US5164294A (en) *	1988-05-17	1992-11-17	Syntex (U.S.A.) Inc.	Method for immunochromatographic analysis
US5334513A (en) *	1988-05-17	1994-08-02	Syntex (U.S.A.) Inc.	Method for immunochromatographic analysis
US5573919A (en) *	1988-06-02	1996-11-12	Carter-Wallace	Assay using an absorbent material
US5620845A (en) *	1988-06-06	1997-04-15	Ampcor, Inc.	Immunoassay diagnostic kit
AU2684488A (en) *	1988-06-27	1990-01-04	Carter-Wallace, Inc.	Test device and method for colored particle immunoassay
US5059522A (en) *	1988-08-18	1991-10-22	Wayne Lawrence G	Intrinsic enzyme dot blot immunoassay or indentification of microorganisms
JPH04502961A (ja) *	1988-11-14	1992-05-28	アイデックス・ラボラトリーズ・インコーポレーテッド	二重吸収被分析物検出
US6306594B1 (en)	1988-11-14	2001-10-23	I-Stat Corporation	Methods for microdispensing patterened layers
US5200051A (en) *	1988-11-14	1993-04-06	I-Stat Corporation	Wholly microfabricated biosensors and process for the manufacture and use thereof
US5028535A (en) *	1989-01-10	1991-07-02	Biosite Diagnostics, Inc.	Threshold ligand-receptor assay
US5939272A (en) *	1989-01-10	1999-08-17	Biosite Diagnostics Incorporated	Non-competitive threshold ligand-receptor assays
US5252293A (en) *	1989-01-17	1993-10-12	Vladimir Drbal	Analytical slide with porous filter membrane
US6352862B1 (en)	1989-02-17	2002-03-05	Unilever Patent Holdings B.V.	Analytical test device for imuno assays and methods of using same
DE69030829T2 (de) *	1989-03-10	1998-01-15	Hoffmann La Roche	Reagenzien zum Nachweis von Drogen
US5106761A (en) *	1989-03-13	1992-04-21	International Canine Genetics, Inc.	Method for detecting molecules in a liquid medium
US5340539A (en) *	1989-03-16	1994-08-23	Chemtrak, Inc.	Non-instrumented cholesterol assay
CA2021309C (en) *	1989-07-17	2003-04-01	Jon J. Michnovicz	Method and materials for detecting pathology from alterations in estrogen metabolism
US5155049A (en) *	1989-08-22	1992-10-13	Terrapin Technologies, Inc.	Blotting technique for membrane assay
US5185127A (en) *	1989-09-21	1993-02-09	Becton, Dickinson And Company	Test device including flow control means
US5075078A (en) *	1989-10-05	1991-12-24	Abbott Laboratories	Self-performing immunochromatographic device
US5376556A (en) *	1989-10-27	1994-12-27	Abbott Laboratories	Surface-enhanced Raman spectroscopy immunoassay
US5646046A (en) *	1989-12-01	1997-07-08	Akzo Nobel N.V.	Method and instrument for automatically performing analysis relating to thrombosis and hemostasis
US5147780A (en) *	1989-12-01	1992-09-15	Sangstat Medical Corporation	Multiwell stat test
US5252496A (en) *	1989-12-18	1993-10-12	Princeton Biomeditech Corporation	Carbon black immunochemical label
US5141850A (en) *	1990-02-07	1992-08-25	Hygeia Sciences, Inc.	Porous strip form assay device method
JP3070764B2 (ja) *	1990-03-12	2000-07-31	バイオサイト・ダイアグノスティックス・インコーポレイテッド	生物学的検定装置及びそれを用いた検定方法
US5922615A (en) *	1990-03-12	1999-07-13	Biosite Diagnostics Incorporated	Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
US5559032A (en) *	1990-06-29	1996-09-24	Pomeroy; Patrick C.	Method and apparatus for post-transfer assaying of material on solid support
US5158869A (en) *	1990-07-06	1992-10-27	Sangstat Medical Corporation	Analyte determination using comparison of juxtaposed competitive and non-competitive elisa results and device therefore
US5143852A (en)	1990-09-14	1992-09-01	Biosite Diagnostics, Inc.	Antibodies to ligand analogues and their utility in ligand-receptor assays
JPH05504841A (ja) *	1990-09-14	1993-07-22	バイオサイト・ダイアグノスティックス・インコーポレイテッド	リガンドレセプター及びリガンドのコンプレックスに対する抗体及びリガンド―レセプターアッセーでのそれらの用途
WO1992005440A1 (en) *	1990-09-26	1992-04-02	Akers Research Corporation	Improved ligand assay
US5231035A (en) *	1991-01-11	1993-07-27	Akers Research Corporation	Latex agglutination assay
US5607863A (en) *	1991-05-29	1997-03-04	Smithkline Diagnostics, Inc.	Barrier-controlled assay device
US5877028A (en)	1991-05-29	1999-03-02	Smithkline Diagnostics, Inc.	Immunochromatographic assay device
US5869345A (en) *	1991-05-29	1999-02-09	Smithkline Diagnostics, Inc.	Opposable-element assay device employing conductive barrier
US6168956B1 (en)	1991-05-29	2001-01-02	Beckman Coulter, Inc.	Multiple component chromatographic assay device
US5468648A (en) *	1991-05-29	1995-11-21	Smithkline Diagnostics, Inc.	Interrupted-flow assay device
US5998220A (en)	1991-05-29	1999-12-07	Beckman Coulter, Inc.	Opposable-element assay devices, kits, and methods employing them
US5264589A (en) *	1991-06-06	1993-11-23	Miles Inc.	Merocyanine protein error indicators
DE4121493A1 (de) *	1991-06-28	1993-01-07	Draegerwerk Ag	Analysevorrichtung zur quantitativen, immunologischen bestimmung von schadstoffen
US5451504A (en) *	1991-07-29	1995-09-19	Serex, Inc.	Method and device for detecting the presence of analyte in a sample
US5726010A (en) *	1991-07-31	1998-03-10	Idexx Laboratories, Inc.	Reversible flow chromatographic binding assay
US6007999A (en) *	1991-07-31	1999-12-28	Idexx Laboratories, Inc.	Reversible flow chromatographic binding assay
EP0610356B1 (de) *	1991-10-18	2001-01-31	SYNSORB Biotech Inc.	Behandlung bakterieller dysenterie
AU3439693A (en) *	1992-01-22	1993-09-01	Abbott Laboratories	Calibration reagents for semi-quantitative binding assays and devices
DE69329377T2 (de) *	1992-03-10	2001-04-05	Quidel Corp	Trennmittel für rote blutkörperchen bei untersuchungen mit spezifischer bindung
DE4216696C2 (de) *	1992-04-10	1995-01-26	Deutsche Aerospace	Verfahren und Vorrichtung zur Empfindlichkeits- und Selektivitätssteigerung bei Immuno-Assays, Molekül-Rezeptor-, DNA-komplementär-DNA- und Gast-Wirtsmolekül-Wechselwirkungs-Assays
US5395754A (en) *	1992-07-31	1995-03-07	Hybritech Incorporated	Membrane-based immunoassay method
US5447838A (en) *	1992-08-05	1995-09-05	Hybritech Incorporated	Protein-dye conjugate for confirmation of correct dilution of calibrators
EP0583980A1 (de) *	1992-08-20	1994-02-23	Eli Lilly And Company	Verfahren zur Herstellung von monoklonalen Antikörpern aus Kaninchen
US5354692A (en) *	1992-09-08	1994-10-11	Pacific Biotech, Inc.	Analyte detection device including a hydrophobic barrier for improved fluid flow
AU670108B2 (en)	1992-09-11	1996-07-04	Becton Dickinson & Company	Improved antibodies to plasmodium falciparum
FI92882C (fi) *	1992-12-29	1995-01-10	Medix Biochemica Ab Oy	Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi
US5344754A (en) *	1993-01-13	1994-09-06	Avocet Medical, Inc.	Assay timed by electrical resistance change and test strip
US5500375A (en) *	1993-04-13	1996-03-19	Serex, Inc.	Integrated packaging-holder device for immunochromatographic assays in flow-through or dipstick formats
US6562333B1 (en)	1993-06-14	2003-05-13	Schering Corporation	Purified mammalian CTLA-8 antigens and related reagents
US5684144A (en) *	1993-07-28	1997-11-04	University Of North Texas	Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof
US5837546A (en) *	1993-08-24	1998-11-17	Metrika, Inc.	Electronic assay device and method
US5770389A (en) *	1993-09-27	1998-06-23	Abbott Laboratories	Apparatus and method for determining the quanity of an analyte in a biological sample by means of transmission photometry
US5695928A (en) *	1993-12-10	1997-12-09	Novartis Corporation	Rapid immunoassay for detection of antibodies or antigens incorporating simultaneous sample extraction and immunogenic reaction
US5561045A (en) *	1994-01-04	1996-10-01	Intracel Corporation	Detection reagent, article, and immunoassay method
US5547833A (en) *	1994-01-04	1996-08-20	Intracel Corporation	Radial flow assay, delivering member, test kit, and methods
US6406855B1 (en)	1994-02-17	2002-06-18	Maxygen, Inc.	Methods and compositions for polypeptide engineering
US6335160B1 (en)	1995-02-17	2002-01-01	Maxygen, Inc.	Methods and compositions for polypeptide engineering
US5550032A (en) *	1994-05-27	1996-08-27	George Mason University	Biological assay for microbial contamination
NZ291624A (en)	1994-08-12	1998-07-28	Myriad Genetics Inc	Method of diagnosis of a predisposition to breast cancer
NZ291621A (en)	1994-08-12	1998-09-24	Myriad Genetics Inc	Isolation and detection of human breast cancer and ovarian cancer predisposing gene, brca1
US6974666B1 (en) *	1994-10-21	2005-12-13	Appymetric, Inc.	Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US8236493B2 (en)	1994-10-21	2012-08-07	Affymetrix, Inc.	Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
JP3010699U (ja) *	1994-10-29	1995-05-02	株式会社ニッポンジーン	直接採尿の可能なクロマト式検査装置
US5633149A (en) *	1994-12-07	1997-05-27	Incyte Pharmaceuticals, Inc.	Polynucleotide encoding novel chemokine expressed in inflamed adenoid
US7005509B1 (en)	1995-02-17	2006-02-28	Incyte Corporation	Chemokine PANEC-1 polynucleotides and compositions and methods related thereto
US5712172A (en)	1995-05-18	1998-01-27	Wyntek Diagnostics, Inc.	One step immunochromatographic device and method of use
US20010051350A1 (en)	1995-05-02	2001-12-13	Albert Nazareth	Diagnostic detection device and method
US5739041A (en) *	1995-05-02	1998-04-14	Carter Wallace, Inc.	Diagnostic detection device
GB0112226D0 (en) *	2001-05-18	2001-07-11	Danisco	Method of improving dough and bread quality
AU6113396A (en)	1995-06-14	1997-01-15	Regents Of The University Of California, The	Novel high affinity human antibodies to tumor antigens
WO1997006439A1 (en)	1995-08-09	1997-02-20	Quidel Corporation	Test strip and method for one step lateral flow assay
US7635597B2 (en)	1995-08-09	2009-12-22	Bayer Healthcare Llc	Dry reagent particle assay and device having multiple test zones and method therefor
US7455964B1 (en)	1996-07-15	2008-11-25	The Hospital For Sick Children	Genes from the 20q13 amplicon and their uses
IL124620A0 (en)	1995-12-18	1998-12-06	Myriad Genetics Inc	Chromosome 13-linked breast cancer susceptibility gene
US5837492A (en)	1995-12-18	1998-11-17	Myriad Genetics, Inc.	Chromosome 13-linked breast cancer susceptibility gene
US7423143B2 (en) *	1996-01-23	2008-09-09	Affymetrix. Inc.	Nucleic acid labeling compounds
US6965020B2 (en)	1996-01-23	2005-11-15	Affymetrix, Inc.	Nucleic acid labeling compounds
US20040210045A1 (en) *	1996-01-23	2004-10-21	Mcgall Glenn	Nucleic acid labeling compounds
US7282327B2 (en) *	1996-01-23	2007-10-16	Affymetrix, Inc.	Nucleic acid labeling compounds
US6864059B2 (en) *	1996-01-23	2005-03-08	Affymetrix, Inc.	Biotin containing C-glycoside nucleic acid labeling compounds
US20010018514A1 (en) *	1998-07-31	2001-08-30	Mcgall Glenn H.	Nucleic acid labeling compounds
US7291463B2 (en) *	1996-01-23	2007-11-06	Affymetrix, Inc.	Nucleic acid labeling compounds
EP0880598A4 (de)	1996-01-23	2005-02-23	Affymetrix Inc	Verfahren zur analyse von nukleinsäure
US5851777A (en) *	1996-02-05	1998-12-22	Dade Behring Inc.	Homogeneous sol-sol assay
US6924094B1 (en) *	1996-02-08	2005-08-02	Affymetrix, Inc.	Chip-based species identification and phenotypic characterization of microorganisms
WO1997029212A1 (en)	1996-02-08	1997-08-14	Affymetrix, Inc.	Chip-based speciation and phenotypic characterization of microorganisms
EP1728875A3 (de)	1996-02-08	2007-05-09	Affymetrix, Inc.	Speziesbestimmung und phenotypische Charakterisierung von Mikroorganismen auf der Basis eines Chips
US5741647A (en) *	1996-02-16	1998-04-21	Tam; Joseph Wing On	Flow through nucleic acid hybridisation uses thereof and a device thereof
US5882644A (en) *	1996-03-22	1999-03-16	Protein Design Labs, Inc.	Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof
EP0888124A4 (de) *	1996-03-22	2001-04-11	Univ Georgia Res Found	Immunogene Zusammenstellungen von Porphyromonas Gingivalis Peptiden und derenVerfahren
US5968839A (en) *	1996-05-13	1999-10-19	Metrika, Inc.	Method and device producing a predetermined distribution of detectable change in assays
US6207153B1 (en) *	1996-05-22	2001-03-27	Viventia Biotech, Inc.	Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US6342349B1 (en)	1996-07-08	2002-01-29	Burstein Technologies, Inc.	Optical disk-based assay devices and methods
US20050214827A1 (en) *	1996-07-08	2005-09-29	Burstein Technologies, Inc.	Assay device and method
AU4055697A (en)	1996-08-16	1998-03-06	Schering Corporation	Mammalian cell surface antigens; related reagents
US5945345A (en) *	1996-08-27	1999-08-31	Metrika, Inc.	Device for preventing assay interference using silver or lead to remove the interferant
US20070299005A1 (en) *	1996-09-24	2007-12-27	Tanox, Inc.	Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
PT932678E (pt)	1996-09-24	2006-07-31	Tanox Inc	Familia de genes que codificam peptidos relacionados com apoptose, peptidos por eles codificados e metodos para sua utilizacao
US5998221A (en) *	1996-09-25	1999-12-07	Becton, Dickinson And Company	Non-instrumented assay with quantitative and qualitative results
JP3869092B2 (ja)	1996-10-01	2007-01-17	ジェロン・コーポレーション	ヒトテロメラーゼ触媒性サブユニット
US6261836B1 (en)	1996-10-01	2001-07-17	Geron Corporation	Telomerase
US6093809A (en)	1996-10-01	2000-07-25	University Technology Corporation	Telomerase
US6610839B1 (en) *	1997-08-14	2003-08-26	Geron Corporation	Promoter for telomerase reverse transcriptase
US7585622B1 (en) *	1996-10-01	2009-09-08	Geron Corporation	Increasing the proliferative capacity of cells using telomerase reverse transcriptase
US6475789B1 (en)	1996-10-01	2002-11-05	University Technology Corporation	Human telomerase catalytic subunit: diagnostic and therapeutic methods
US6808880B2 (en) *	1996-10-01	2004-10-26	Geron Corporation	Method for detecting polynucleotides encoding telomerase
GB9907461D0 (en)	1999-03-31	1999-05-26	King S College London	Neurite regeneration
US5710005A (en) *	1996-10-29	1998-01-20	Biocode, Inc.	Analyte detection with a gradient lateral flow device
DE69738811D1 (de)	1996-12-13	2008-08-14	Schering Corp	Oberflächenantigene aus Säugern
US5879951A (en) *	1997-01-29	1999-03-09	Smithkline Diagnostics, Inc.	Opposable-element assay device employing unidirectional flow
CA2279231C (en)	1997-02-07	2013-11-26	The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services	Activity dependent neurotrophic factor iii (adnf iii)
CA2286910A1 (en)	1997-03-05	1998-09-11	Raouf A. Guirguis	Fluid specimen collecting and testing apparatus
US7413864B2 (en) *	1997-04-18	2008-08-19	Geron Corporation	Treating cancer using a telomerase vaccine
US7622549B2 (en) *	1997-04-18	2009-11-24	Geron Corporation	Human telomerase reverse transcriptase polypeptides
US20050013825A1 (en) *	1997-04-18	2005-01-20	Geron Corporation	Vaccine containing the catalytic subunit of telomerase for treating cancer
US6103536A (en) *	1997-05-02	2000-08-15	Silver Lake Research Corporation	Internally referenced competitive assays
EP1988166A1 (de)	1997-05-07	2008-11-05	Schering Corporation	Menschliche Toll-Like-Rezeptorproteine, zugehörige Reagenzien und Verfahren
US5939252A (en) *	1997-05-09	1999-08-17	Lennon; Donald J.	Detachable-element assay device
US7115722B1 (en)	1997-05-22	2006-10-03	Viventia Biotech, Inc.	Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US6258548B1 (en)	1997-06-05	2001-07-10	A-Fem Medical Corporation	Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules
US20020122807A1 (en) *	1998-07-07	2002-09-05	Dan Michael D.	Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
JP2002509438A (ja)	1997-07-09	2002-03-26	シェーリングコーポレイション	単離された樹状細胞膜タンパク質遺伝子
US6228638B1 (en)	1997-07-11	2001-05-08	University Of North Texas, Health Science Center At Fort Worth	Escherichia coli CSRB gene and RNA encoded thereby
US6506579B1 (en)	1997-07-15	2003-01-14	Genencor International, Inc.	Increasing production of proteins in gram-positive microorganisms using SecG
US6762039B2 (en) *	1997-07-15	2004-07-13	Genencor International, Inc.	Bacillus subtillis with an inactivated cysteine protease-1
US20030157642A1 (en)	1997-07-15	2003-08-21	Caldwell Robert M.	Increasing production of proteins in gram-positive microorganisms
US6723550B1 (en) *	1997-07-15	2004-04-20	Genencor International, Inc.	Proteases from gram-positive organisms
US6521421B1 (en)	1997-07-16	2003-02-18	Genencor International, Inc.	Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same
PE20000183A1 (es)	1997-07-25	2000-03-11	Schering Corp	Citoquinas de mamiferos y reactivos relacionados
DE69836082T2 (de)	1997-08-01	2007-05-10	Schering Corp.	Membranproteine aus säugetierzellen; verwandte reagentien
US6180411B1 (en)	1997-08-01	2001-01-30	The Regents Of The University Of California	Light-triggered indicators that memorize analyte concentrations
US7252950B1 (en)	1997-09-04	2007-08-07	The Regents Of The University Of California	Assays for detecting modulators of cytoskeletal function
US6960457B1 (en)	1997-09-04	2005-11-01	Stanford University	Reversible immobilization of arginine-tagged moieties on a silicate surface
US6300117B1 (en) *	1997-09-15	2001-10-09	Genencor International, Inc.	Proteases from gram-positive organisms
US6521440B1 (en)	1997-09-15	2003-02-18	Genencor International, Inc.	Proteases from gram-positive organisms
US7378244B2 (en) *	1997-10-01	2008-05-27	Geron Corporation	Telomerase promoters sequences for screening telomerase modulators
US6316241B1 (en) *	1997-11-20	2001-11-13	Genencor International, Inc.	Alpha/beta hydrolase-fold enzymes
GB9724629D0 (en) *	1997-11-20	1998-01-21	Genencor Int Bv	Alpha/beta hydrolase-fold enzymes
GB9724627D0 (en)	1997-11-20	1998-01-21	Genencor Int Bv	Gram positive microorganism formate pathway
GB9726398D0 (en)	1997-12-12	1998-02-11	Isis Innovation	Polypeptide and coding sequences
US6599731B1 (en)	1997-12-30	2003-07-29	Genencor International, Inc.	Proteases from gram positive organisms
GB9727470D0 (en) *	1997-12-30	1998-02-25	Genencor Int Bv	Proteases from gram positive organisms
US6465186B1 (en) *	1997-12-30	2002-10-15	Genecor International, Inc.	Proteases from gram positive organisms
US6528255B1 (en) *	1997-12-30	2003-03-04	Genencor International, Inc.	Proteases from gram positive organisms
US6780609B1 (en)	1998-10-23	2004-08-24	Genome Therapeutics Corporation	High bone mass gene of 1.1q13.3
US6759243B2 (en)	1998-01-20	2004-07-06	Board Of Trustees Of The University Of Illinois	High affinity TCR proteins and methods
US6673914B1 (en)	1998-01-22	2004-01-06	John Wayne Cancer Institute	Human tumor-associated gene
US6764830B1 (en)	1998-01-23	2004-07-20	The Regents Of The University Of California	Thermomyces lanuginosus kinesin motor protein and methods of screening for modulators of kinesin proteins
US6267722B1 (en)	1998-02-03	2001-07-31	Adeza Biomedical Corporation	Point of care diagnostic systems
US6394952B1 (en)	1998-02-03	2002-05-28	Adeza Biomedical Corporation	Point of care diagnostic systems
US6596501B2 (en)	1998-02-23	2003-07-22	Fred Hutchinson Cancer Research Center	Method of diagnosing autoimmune disease
AU2980199A (en)	1998-03-04	1999-09-20	Genencor International, Inc.	Modified forms of pullulanase
US6284194B1 (en)	1998-03-11	2001-09-04	Albert E. Chu	Analytical assay device and methods using surfactant treated membranes to increase assay sensitivity
CA2323812C (en)	1998-03-20	2011-05-10	The Curators Of The University Of Missouri	Early pregnancy diagnosis using pags (pregnancy-associated glycoproteins)
US8062908B2 (en) *	1999-03-29	2011-11-22	Orasure Technologies, Inc.	Device for collection and assay of oral fluids
US6303081B1 (en) *	1998-03-30	2001-10-16	Orasure Technologies, Inc.	Device for collection and assay of oral fluids
DK1086372T3 (da)	1998-03-30	2006-09-18	Orasure Technologies Inc	Opsamlingsindretning til enkelttrinsanalyse af mundvæsker
WO1999049774A2 (en) *	1998-03-31	1999-10-07	Genzyme Corporation	Methods for the diagnosis and treatment of lung cancer
US6337200B1 (en) *	1998-03-31	2002-01-08	Geron Corporation	Human telomerase catalytic subunit variants
US6274314B1 (en)	1998-04-02	2001-08-14	Nyxis Neurotherapies, Inc.	Diagnostic assay for the modified nucleosides pseudouridine, 7-methyladenosine, or 1-methyladenosine
US7108968B2 (en) *	1998-04-03	2006-09-19	Affymetrix, Inc.	Mycobacterial rpoB sequences
US6872537B1 (en)	1998-04-14	2005-03-29	Regents Of The University Of California	Assays for the detection of microtubule depolymerization inhibitors
JP2002522747A (ja)	1998-04-14	2002-07-23	ザリージェンツオブザユニバーシティオブカリフォルニア	微小管脱重合インヒビターを検出するためのアッセイ
US6699969B1 (en)	1998-04-14	2004-03-02	The Regents Of The University Of California	Assays for the detection of microtubule depolymerization inhibitors
US6348573B1 (en)	1998-04-27	2002-02-19	The Regents Of The University Of Michigan	Compositions and methods for identifying apoptosis signaling pathway inhibitors and activators
US6271044B1 (en)	1998-05-06	2001-08-07	University Of Pittsburgh Of The Commonwealth System Of Higher Education	Method and kit for detecting an analyte
AU5080699A (en) *	1998-07-21	2000-02-14	Burstein Laboratories, Inc.	Optical disc-based assay devices and methods
WO2000005396A1 (en)	1998-07-21	2000-02-03	Danisco A/S	Foodstuff
US7402400B2 (en)	2001-07-03	2008-07-22	Regents Of The University Of California	Mammalian sweet taste receptors
EP1806362B1 (de)	1998-07-28	2010-07-21	The Regents of the University of California	Nukleinsäuren, die für einen an ein G-Protein gekoppelten, an der sensorischen Transduktion beteiligten Rezeptor kodieren
SE9803099D0 (sv)	1998-09-13	1998-09-13	Karolinska Innovations Ab	Nucleic acid transfer
AU6246199A (en)	1998-09-21	2000-04-10	Schering Corporation	Human interleukin-b50, therapeutic uses
EP0997476A3 (de)	1998-09-25	2000-07-19	Schering-Plough	Antikörper gegen ein Antigen auf Langerhans Zellen in Säugetieren und deren Verwendungen
US7071324B2 (en) *	1998-10-13	2006-07-04	Brown University Research Foundation	Systems and methods for sequencing by hybridization
JP3622532B2 (ja) *	1998-10-13	2005-02-23	松下電器産業株式会社	酵素免疫分析用試薬及びそれを用いた分析方法
EP1123401A1 (de)	1998-10-22	2001-08-16	The General Hospital Corporation	Bioaktive peptide und peptid-derivate von parathyroidhormon (pth) und parathyroidhormon verwandte peptide (pthrp)
US7297554B2 (en) *	1998-11-18	2007-11-20	Microdiagnostics, Inc.	Immunoassay system
US6638760B1 (en)	1998-11-25	2003-10-28	Pe Corporation (Ny)	Method and apparatus for flow-through hybridization
KR20010089764A (ko)	1999-01-11	2001-10-08	둘락 노먼 씨.	인터류킨-17과 관련된 포유류의 사이토카인, 이를코딩하는 폴리뉴클레오티드 및 이의 용도
WO2000042430A1 (en) *	1999-01-15	2000-07-20	Medtox Scientific, Inc.	Lateral flow test strip
US6156515A (en) *	1999-02-09	2000-12-05	Urocor, Inc.	Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
DE60041393D1 (de)	1999-03-11	2009-03-05	Schering Corp	Cytokine aus säugetieren, verwandte reagenzien und verfahren
WO2000058456A2 (en) *	1999-03-30	2000-10-05	Board Of Regents, The University Of Texas System	Compositions and methods for modifying toxic effects of proteinacious compounds
MXPA01011519A (es)	1999-05-13	2003-08-20	Medical Res Council	Homologos del receptor ox2.
EP2385124B1 (de)	1999-05-14	2013-09-11	Arbor Vita Corporation	Peptide oder Peptidanaloga zur Modulation der Bindung zwischen einem PDZ-Protein und einem PL-Protein
ES2322791T5 (es)	1999-06-01	2013-11-29	Merck Sharp & Dohme Corp.	Proteínas receptoras de mamíferos; reactivos y métodos relacionados
GB9914210D0 (en)	1999-06-17	1999-08-18	Danisco	Promoter
JP2003506026A (ja)	1999-07-30	2003-02-18	シェーリングコーポレイション	哺乳動物サイトカイン；関連試薬
EP3184637A1 (de)	1999-09-09	2017-06-28	Merck Sharp & Dohme Corp.	Komplexe aus säugetier-interleukin-12 p40 und interleukin b30, antikörper, verwendung in pharmazeutischen zusammensetzungen
WO2001023521A2 (en) *	1999-09-29	2001-04-05	The General Hospital Corporation	Polypeptide derivatives of parathyroid hormone (pth)
US7332275B2 (en)	1999-10-13	2008-02-19	Sequenom, Inc.	Methods for detecting methylated nucleotides
US6306665B1 (en)	1999-10-13	2001-10-23	A-Fem Medical Corporation	Covalent bonding of molecules to an activated solid phase material
ATE456575T1 (de)	1999-10-18	2010-02-15	Prince Henrys Inst Med Res	Immun-interaktive fragmente der alpha-c- untereinheit von inhibin
US7030228B1 (en)	1999-11-15	2006-04-18	Miltenyi Biotec Gmbh	Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
JP2003516324A (ja)	1999-11-24	2003-05-13	シェーリングコーポレイション	転移を阻害する方法
US6458326B1 (en)	1999-11-24	2002-10-01	Home Diagnostics, Inc.	Protective test strip platform
WO2001048145A2 (en)	1999-12-06	2001-07-05	Board Of Trustees Of The University Of Illinois	High affinity tcr proteins and methods
FR2802214B1 (fr) *	1999-12-09	2005-07-22	Biomerieux Sa	Nouveaux substrats chromogenes a base d'alizarine, leurs utilisations et compositions contenant de tels substrats
US6544792B1 (en) *	1999-12-21	2003-04-08	Genencor International, Inc.	Production of secreted polypeptides
NZ520445A (en)	2000-01-25	2004-02-27	Univ Queensland	Proteins comprising conserved regions of neisseria meningitidis surface antigen NhhA
US20010051348A1 (en) *	2000-01-28	2001-12-13	Lee Chee Wee	Novel ligands and methods for preparing same
DE10003734A1 (de) *	2000-01-28	2001-08-02	Bosch Gmbh Robert	Detektionsverfahren und -vorrichtung
ATE483970T1 (de)	2000-02-08	2010-10-15	Sangamo Biosciences Inc	Zellen zur entdeckung von medikamenten
EP1172653A4 (de) *	2000-02-18	2003-07-16	Matsushita Electric Ind Co Ltd	Überwachungschip für vorrichtung zum messen von sensoren
TW201006846A (en)	2000-03-07	2010-02-16	Senomyx Inc	T1R taste receptor and genes encidung same
CA2399202A1 (en) *	2000-03-09	2001-09-13	Heska Corporation	Use of recombinant antigens to determine the immune status of an animal
US8288128B2 (en) *	2004-11-18	2012-10-16	Eppendorf Array Technologies S.A.	Real-time quantification of multiple targets on a micro-array
US7875442B2 (en) *	2000-03-24	2011-01-25	Eppendorf Array Technologies	Identification and quantification of a plurality of biological (micro)organisms or their components
US7829313B2 (en) *	2000-03-24	2010-11-09	Eppendorf Array Technologies	Identification and quantification of a plurality of biological (micro)organisms or their components
US20030108927A1 (en) *	2000-04-03	2003-06-12	Kathryn Leishman	Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases
US6699722B2 (en)	2000-04-14	2004-03-02	A-Fem Medical Corporation	Positive detection lateral-flow apparatus and method for small and large analytes
CA2406245A1 (en)	2000-04-18	2001-10-25	Schering Corporation	Il-174 uses, compositions and methods
AU6110301A (en)	2000-04-29	2001-11-12	Univ Iowa Res Found	Diagnostics and therapeutics for macular degeneration-related disorders
PL209128B1 (pl)	2000-05-10	2011-07-29	Schering Corp	Białko receptora spokrewnionego z receptorami cytokin oraz związane z nim produkty, sposoby i zastosowania
US7422743B2 (en)	2000-05-10	2008-09-09	Schering Corporation	Mammalian receptor protein DCRS5;methods of treatment
AUPQ755300A0 (en)	2000-05-17	2000-06-08	Monash University	Immune potentiating compositions
JP2003533996A (ja)	2000-05-25	2003-11-18	シェーリングコーポレイション	ヒトレセプタータンパク質、関連試薬および方法
WO2005000087A2 (en) *	2003-06-03	2005-01-06	Chiron Corporation	Gene products differentially expressed in cancerous colon cells and their methods of use ii
US6528321B1 (en)	2000-06-26	2003-03-04	Beckman Coulter, Inc.	Opposable-element chromatographic assay device for detection of analytes in whole blood samples
US6673614B2 (en)	2000-06-27	2004-01-06	Cell Genesys, Inc.	Rapid methods and kits for detection and semi-quantitation of anti-adenovirus antibody
US6958214B2 (en)	2000-07-10	2005-10-25	Sequenom, Inc.	Polymorphic kinase anchor proteins and nucleic acids encoding the same
GB0020498D0 (en)	2000-08-18	2000-10-11	Sterix Ltd	Compound
US6372516B1 (en)	2000-09-07	2002-04-16	Sun Biomedical Laboratories, Inc.	Lateral flow test device
CA2419979A1 (en)	2000-09-08	2002-03-14	Schering Corporation	Mammalian genes; related reagents and methods
DE60142840D1 (de)	2000-09-08	2010-09-30	Univ Texas	Durch phagendisplay identifizierte zielpeptide des menschen und der maus
US6673623B1 (en)	2000-09-12	2004-01-06	Novocure, Inc.	Methods and compositions that control lipid production
WO2002022667A2 (en) *	2000-09-18	2002-03-21	Genencor International, Inc.	Twin-arginine translocation in bacillus
AU2001294654A1 (en) *	2000-09-25	2002-04-08	The Regents Of The University Of California	Model for neurodegenerative diseases involving amyloid accumulation
US7052831B2 (en) *	2000-09-29	2006-05-30	Becton Dickinson And Company	Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device
US7045283B2 (en)	2000-10-18	2006-05-16	The Regents Of The University Of California	Methods of high-throughput screening for internalizing antibodies
US6890734B2 (en)	2000-11-10	2005-05-10	Schering Corporation	Nucleic acids encoding a cytokine receptor complex
JP2004514445A (ja) *	2000-11-29	2004-05-20	リンクス　バイオテック　ジーエムビーエイチ	新規な網膜特異的ヒトタンパク質Ｃ７ｏｒｆ９、Ｃ１２ｏｒｆ７、ＭＰＰ４およびＦ３７９
US20020165149A1 (en) *	2000-12-08	2002-11-07	Kranz David M.	Mutated class II major histocompatibility proteins
TW201022287A (en)	2001-01-03	2010-06-16	Senomyx Inc	T1R taste receptors and genes encoding same
GB0101762D0 (en) *	2001-01-23	2001-03-07	Medical Res Council	Method
US7087389B2 (en) *	2001-02-09	2006-08-08	Council Of Scientific & Industrial Research	Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity
US20020168663A1 (en) *	2001-02-27	2002-11-14	Phan Brigitte Chau	Methods for DNA conjugation onto solid phase including related optical biodiscs and disc drive systems
US6525330B2 (en)	2001-02-28	2003-02-25	Home Diagnostics, Inc.	Method of strip insertion detection
US6541266B2 (en)	2001-02-28	2003-04-01	Home Diagnostics, Inc.	Method for determining concentration of an analyte in a test strip
US6562625B2 (en)	2001-02-28	2003-05-13	Home Diagnostics, Inc.	Distinguishing test types through spectral analysis
EP1385829A4 (de) *	2001-03-12	2005-10-19	Affymetrix Inc	Verbindungen zur nukleinsäuremarkierung
US20030104410A1 (en) *	2001-03-16	2003-06-05	Affymetrix, Inc.	Human microarray
US20030228639A1 (en) *	2001-03-19	2003-12-11	Wright George L	Prostate cancer markers
US20030220475A1 (en) *	2001-04-03	2003-11-27	Fields Howard A.	Neutralizing immunogenic hev polypepetides
US7618789B2 (en) *	2001-04-06	2009-11-17	The United States Of America As Represented By The Secretary Of Department Of Health And Human Services	Use of semenogelin in the diagnosis, prognosis and treatment of cancer
WO2002084291A1 (fr) *	2001-04-12	2002-10-24	Arkray, Inc.	Instrument d'analyse de prelevement
US6916626B1 (en) *	2001-04-25	2005-07-12	Rockeby Biomed Ltd.	Detection of Candida
BR0209154A (pt)	2001-05-18	2004-07-20	Danisco	Processo de preparação de uma massa com uma enzima
EP1990057A1 (de)	2001-05-22	2008-11-12	Merck & Co., Inc.	Beta-Sekretase-Substrate und ihre Verwendung
AU2002312410A1 (en) *	2001-06-08	2002-12-23	Target Protein Technologies, Inc.	Tissue-specific endothelial membrane proteins
US20070190534A1 (en) *	2001-06-11	2007-08-16	Genesis Genomics Inc.	Mitochondrial sites and genes associated with prostate cancer
CA2451317C (en)	2001-06-26	2016-03-29	Senomyx, Inc.	T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7141416B2 (en) *	2001-07-12	2006-11-28	Burstein Technologies, Inc.	Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith
JP4837888B2 (ja) *	2001-07-23	2011-12-14	ザジェネラルホスピタルコーポレイション	コンホメーションが拘束された副甲状腺ホルモン（ｐｔｈ）類似体
US7300633B2 (en)	2001-07-25	2007-11-27	Oakville Hong Kong Company Limited	Specimen collection container
JP4265149B2 (ja) *	2001-07-25	2009-05-20	セイコーエプソン株式会社	電気光学装置、電気光学装置の製造方法
US7270959B2 (en)	2001-07-25	2007-09-18	Oakville Hong Kong Company Limited	Specimen collection container
ATE481497T1 (de) *	2001-08-01	2010-10-15	Univ Utah	Am n-terminus trunkierte isoformen von zyklischen phosphodiesterasen pde3a
US6833441B2 (en) *	2001-08-01	2004-12-21	Abmaxis, Inc.	Compositions and methods for generating chimeric heteromultimers
US20030082596A1 (en) *	2001-08-08	2003-05-01	Michael Mittmann	Methods of genetic analysis of probes: test3
US6855561B2 (en)	2001-09-10	2005-02-15	Quidel Corporation	Method for adding an apparent non-signal line to a lateral flow assay
US20060068405A1 (en) *	2004-01-27	2006-03-30	Alex Diber	Methods and systems for annotating biomolecular sequences
WO2003024993A2 (en)	2001-09-20	2003-03-27	Board Of Regents, The University Of Texas System	Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using elisa assays
US7582425B2 (en) *	2001-09-21	2009-09-01	The Regents Of The University Of Michigan	Atlastin
US7108975B2 (en) *	2001-09-21	2006-09-19	Regents Of The University Of Michigan	Atlastin
EP1961293A3 (de)	2001-09-27	2009-01-28	Pioneer Hi-Bred International, Inc.	Phytatpolynucleotide und Verfahren zu ihrer Verwendung
AU2002330102A1 (en) *	2001-09-28	2003-04-14	Aspenbio, Inc.	Bovine pregnancy test
US20030077282A1 (en)	2001-10-12	2003-04-24	Bigler Michael Eric	Use of bispecific antibodies to regulate immune responses
US7537731B2 (en) *	2001-10-19	2009-05-26	Panasonic Corporation	Specific binding analysis device
US7175983B2 (en) *	2001-11-02	2007-02-13	Abmaxis, Inc.	Adapter-directed display systems
WO2003043524A2 (en)	2001-11-20	2003-05-30	The Curators Of The University Of Missouri	Compositions and methods for accurate early pregnancy diagnosis
US6952704B2 (en) *	2001-11-26	2005-10-04	Microsoft Corporation	Extending a directory schema independent of schema modification
US20030099621A1 (en)	2001-11-29	2003-05-29	Robert Chow	Stem cell screening and transplantation therapy for HIV infection
JP4489431B2 (ja) *	2001-12-07	2010-06-23	ユニバーシティオブワイオミング	喘息の診断に用いる方法および組成物
JP4551660B2 (ja) *	2001-12-12	2010-09-29	プロテオムシステムズリミテッド	診断検査方法
US7244393B2 (en)	2001-12-21	2007-07-17	Kimberly-Clark Worldwide, Inc.	Diagnostic device and system
US6837171B1 (en)	2002-04-29	2005-01-04	Palmer/Snyder Furniture Company	Lightweight table with unitized table top
US8367013B2 (en) *	2001-12-24	2013-02-05	Kimberly-Clark Worldwide, Inc.	Reading device, method, and system for conducting lateral flow assays
US20030119203A1 (en)	2001-12-24	2003-06-26	Kimberly-Clark Worldwide, Inc.	Lateral flow assay devices and methods for conducting assays
US20050003459A1 (en) *	2002-01-30	2005-01-06	Krutzik Siegfried Richard	Multi-purpose optical analysis disc for conducting assays and related methods for attaching capture agents
US7255986B2 (en) *	2002-01-31	2007-08-14	The Board Of Trustees Operating Michigan State University	Compositions for the diagnosis and treatment of epizootic catarrhal enteritis in ferrets
DK2311869T3 (da)	2002-02-01	2013-03-18	Merck Sharp & Dohme	Anvendelse af pattedyrcytokinrelaterede reagenser
US7094579B2 (en)	2002-02-13	2006-08-22	Xoma Technology Ltd.	Eukaryotic signal sequences for prokaryotic expression
WO2003072710A2 (en) *	2002-02-21	2003-09-04	Eastern Virginia Medical School	Protein biomarkers that distinguish prostate cancer from non-malignant cells
WO2003072799A2 (en)	2002-02-22	2003-09-04	The Government Of The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services	Brother of the regulator of imprinted sites (boris)
US7053188B2 (en)	2002-02-22	2006-05-30	Purdue Research Foundation	Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
US6703216B2 (en)	2002-03-14	2004-03-09	The Regents Of The University Of California	Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB)
US7332585B2 (en)	2002-04-05	2008-02-19	The Regents Of The California University	Bispecific single chain Fv antibody molecules and methods of use thereof
JP2004003976A (ja) *	2002-04-05	2004-01-08	Matsushita Electric Ind Co Ltd	特異結合分析方法およびこれに用いるデバイス
CA2391438A1 (en) *	2002-05-01	2003-11-01	Procyon Biopharma Inc.	Psp94 diagnostic reagents and assays
US7534580B2 (en) *	2002-05-01	2009-05-19	Ambrilia Biopharma Inc.	PSP94 diagnostic reagents and assays
AU2003243199B2 (en) *	2002-05-02	2008-08-21	Aspenbio Pharma, Inc	Pregnancy detection
CA2484676A1 (en) *	2002-05-03	2003-11-13	Sequenom, Inc.	Kinase anchor protein muteins, peptides thereof, and related methods
EP1532453B1 (de) *	2002-05-31	2013-08-21	Genetic Technologies Limited	Maternale antikörper als marker für fötale zellen zur identifizierung und anreicherung fötaler zellen aus maternalem blut
EP1539931A4 (de)	2002-06-27	2006-08-23	Univ Queensland	Differenzierungsmodulierende agentien und verwendungen dafür
US7504215B2 (en)	2002-07-12	2009-03-17	Affymetrix, Inc.	Nucleic acid labeling methods
ATE497774T1 (de)	2002-07-15	2011-02-15	Univ Texas	Screening kombinatorischer proteinbibliotheken mittels periplasmatischer expression
CN104001181B (zh)	2002-07-15	2017-05-10	得克萨斯大学体系董事会	与阴离子磷脂和氨基磷脂结合的选定抗体及其治疗和诊断用途
US7794716B2 (en)	2002-07-25	2010-09-14	Glenveigh Pharmaceuticals, Llc	Antibody composition and passive immunization against pregnancy-induced hypertension
HUE025624T2 (en)	2002-07-26	2016-04-28	The Walter And Eliza Hall Inst Of Medical Res	Immunogenic preparations and diagnostic and therapeutic use
EP2436774A3 (de)	2002-08-01	2012-06-13	The Regents of The University of California	Therapeutische monoklonale Antikörper zur Neutralisierung von Botulinumneurotoxinen
EA200500330A1 (ru) *	2002-08-10	2006-06-30	Йейл Юниверсити	Антагонисты nogo рецепторов
EP2204654B1 (de)	2002-08-13	2012-12-12	N-Dia, Inc.	Verwendung von Vorrichtungen und Verfahren zur Erkennung von Fruchtwasser in vaginalen Sekretionen
ES2311751T3 (es)	2002-08-23	2009-02-16	Bayer Healthcare Ag	Biomarcadores de polipeptidos para la diagnosis de la enfermedad de alzheimer.
US7285424B2 (en)	2002-08-27	2007-10-23	Kimberly-Clark Worldwide, Inc.	Membrane-based assay devices
US7314763B2 (en)	2002-08-27	2008-01-01	Kimberly-Clark Worldwide, Inc.	Fluidics-based assay devices
US7432105B2 (en)	2002-08-27	2008-10-07	Kimberly-Clark Worldwide, Inc.	Self-calibration system for a magnetic binding assay
ATE418072T1 (de)	2002-09-09	2009-01-15	Arbor Vita Corp	Verfahren zur diagnose von gebärmutterhalskrebs
US6774758B2 (en) *	2002-09-11	2004-08-10	Kalyan P. Gokhale	Low harmonic rectifier circuit
US20050042621A1 (en) *	2002-09-27	2005-02-24	Affymetrix, Inc.	Method for preparing a nucleic acid sample for hybridization to an array
CN1318142C (zh) *	2002-10-11	2007-05-30	Zbx公司	诊断装置
KR20050059294A (ko)	2002-10-24	2005-06-17	스테릭스 리미티드	11-베타-하이드록시 스테로이드 데하이드로게나제 형태 1및 형태 2의 억제제
US7241626B2 (en) *	2002-11-12	2007-07-10	Strategic Diagnostics Inc.	Isolation and confirmation of analytes from test devices
US7250289B2 (en) *	2002-11-20	2007-07-31	Affymetrix, Inc.	Methods of genetic analysis of mouse
US7314750B2 (en) *	2002-11-20	2008-01-01	Affymetrix, Inc.	Addressable oligonucleotide array of the rat genome
US7781172B2 (en)	2003-11-21	2010-08-24	Kimberly-Clark Worldwide, Inc.	Method for extending the dynamic detection range of assay devices
EP1594975A4 (de)	2002-12-04	2006-08-02	Applera Corp	Multiplex-amplifikation von polynukleotiden
US20040121334A1 (en)	2002-12-19	2004-06-24	Kimberly-Clark Worldwide, Inc.	Self-calibrated flow-through assay devices
US7247500B2 (en)	2002-12-19	2007-07-24	Kimberly-Clark Worldwide, Inc.	Reduction of the hook effect in membrane-based assay devices
EP1604183B1 (de) *	2002-12-26	2012-08-29	Meso Scale Technologies, LLC.	Verfahren zur biomarker extraktion
WO2004057940A2 (en) *	2002-12-31	2004-07-15	Pharmacia & Upjohn Company Llc	Canine dioxin/aryl hydrocarbon receptor sequences
JP2006512075A (ja) *	2002-12-31	2006-04-13	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	イヌｃｙｐ１ａ２配列
JP2006512076A (ja) *	2002-12-31	2006-04-13	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	イヌ（ｃａｎｉｎｅ）Ｌ−ＰＢＥ配列
US7560272B2 (en)	2003-01-04	2009-07-14	Inverness Medical Switzerland Gmbh	Specimen collection and assay container
DE602004030000D1 (de) *	2003-01-17	2010-12-23	Danisco	Verfahren zur in-situ-herstellung eines emulgators in einem nahrungsmittel
US20050196766A1 (en)	2003-12-24	2005-09-08	Soe Jorn B.	Proteins
US7955814B2 (en)	2003-01-17	2011-06-07	Danisco A/S	Method
ES2375492T3 (es)	2003-01-17	2012-03-01	Danisco A/S	Procedimiento para la producción in situ de un emulsionante en un alimento.
US20100143442A1 (en)	2003-02-05	2010-06-10	Queensland University Of Technology	Growth factor complexes and modulation of cell migration and growth
AU2003900481A0 (en)	2003-02-05	2003-02-20	Queensland University Of Technology	Synthetic modulators of cell migration and growth
WO2004074325A2 (en) *	2003-02-14	2004-09-02	Salmedix, Inc	Compositions and methods for the detection and treatment of methylthioadenosine phosphorylase deficient cancers
US20060141470A1 (en) *	2003-02-14	2006-06-29	Kalayoglu Murat V	Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof
US8394582B2 (en) *	2003-03-05	2013-03-12	Genetic Technologies, Inc	Identification of fetal DNA and fetal cell markers in maternal plasma or serum
ES2360291T3 (es)	2003-03-07	2011-06-02	New England Medical Center Hospitals, Inc.	TRATAMIENTO DE ENFERMEDADES POR DEPOSICIÓN DE IgA1.
AU2003220380A1 (en) *	2003-03-19	2004-11-19	Bristol-Myers Squibb Company	CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH Alpha-HELIX STABILIZERS
AU2003901325A0 (en) *	2003-03-21	2003-04-03	Stephen Locarnini	Therapeutic, prophylactic and diagnostic agents
AU2004224825A1 (en) *	2003-03-26	2004-10-07	Crc For Asthma Limited	Therapeutic and prophylactic compositions and uses therefor
US7851209B2 (en)	2003-04-03	2010-12-14	Kimberly-Clark Worldwide, Inc.	Reduction of the hook effect in assay devices
US20040197819A1 (en)	2003-04-03	2004-10-07	Kimberly-Clark Worldwide, Inc.	Assay devices that utilize hollow particles
ES2369498T3 (es)	2003-04-04	2011-12-01	Yeda Research And Development Co., Ltd.	Anticuerpos para inhibir la actividad de mmp-2 y mmp-9.
WO2004093893A2 (en) *	2003-04-16	2004-11-04	Biogen Idec Ma Inc.	Nogo-receptor antagonists for the treatment of conditions involving amyloid plaques
US7321065B2 (en) *	2003-04-18	2008-01-22	The Regents Of The University Of California	Thyronamine derivatives and analogs and methods of use thereof
US20060286679A1 (en) *	2003-05-27	2006-12-21	Mitsubishi Kagaku Latron, Inc.	Immunochromatographic method
US20060246526A1 (en) *	2003-06-02	2006-11-02	Gyros Patent Ab	Microfluidic affinity assays with improved performance
WO2004110384A2 (en) *	2003-06-12	2004-12-23	Vaxgen, Inc.	Hiv-1 envelope glycoproteins having unusual disulfide structure
JP4871128B2 (ja)	2003-07-17	2012-02-08	ザジェネラルホスピタルコーポレイション	高次構造的に制約された副甲状腺ホルモン（ｐｔｈ）アナログ
US20050014734A1 (en) *	2003-07-18	2005-01-20	Genovate Biotechnology Co., Ltd.	Modulation of interleukin-10 by DHEA
NZ545747A (en)	2003-08-06	2010-06-25	Senomyx Inc	T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds
CA2534661A1 (en)	2003-08-08	2005-02-17	Genenews Inc.	Osteoarthritis biomarkers and uses thereof
US20050064479A1 (en) *	2003-08-12	2005-03-24	Affymetrix, Inc.	Compounds and methods for post incorporation labeling of nucleic acids
DE602004029368D1 (de)	2003-08-14	2010-11-11	Exelixis Inc	Ups als den beta-catenin-pfad modifizierende substanzen und anwendungsverfahren
US7517495B2 (en)	2003-08-25	2009-04-14	Inverness Medical Switzerland Gmbh	Biological specimen collection and analysis system
WO2005029091A2 (en)	2003-09-15	2005-03-31	Oklahoma Medical Research Foundation	Method of using cytokine assays to diagnose, treat, and evaluate inflammatory and autoimmune diseases
CA2539490A1 (en)	2003-09-18	2005-03-24	Genmab A/S	Differentially expressed tumour-specific polypeptides for use in the diagnosis and treatment of cancer
JP4933258B2 (ja) *	2003-09-22	2012-05-16	クイデルコーポレーション	試料中の複数分析物の検出装置
US20050064435A1 (en) *	2003-09-24	2005-03-24	Xing Su	Programmable molecular barcodes
US20050079484A1 (en) *	2003-10-10	2005-04-14	Heineman William Richard	Method of detecting biological materials in liquid
US7910296B2 (en)	2003-10-21	2011-03-22	Orion Genomics Llc	Methods for quantitative determination of methylation density in a DNA locus
US20050227251A1 (en)	2003-10-23	2005-10-13	Robert Darnell	Method of purifying RNA binding protein-RNA complexes
PE20090047A1 (es)	2003-11-10	2009-01-26	Schering Corp	Anticuerpo recombinante humanizado anti-interleuquina 10
US7943395B2 (en)	2003-11-21	2011-05-17	Kimberly-Clark Worldwide, Inc.	Extension of the dynamic detection range of assay devices
US20050112703A1 (en)	2003-11-21	2005-05-26	Kimberly-Clark Worldwide, Inc.	Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7713748B2 (en)	2003-11-21	2010-05-11	Kimberly-Clark Worldwide, Inc.	Method of reducing the sensitivity of assay devices
WO2005052006A2 (en)	2003-11-25	2005-06-09	The Government Of The United States, As Represented By The Secretary Of Health And Human Services	Mutated anti-cd22 antibodies and immunoconjugates
US7943089B2 (en)	2003-12-19	2011-05-17	Kimberly-Clark Worldwide, Inc.	Laminated assay devices
CA2551560A1 (en)	2003-12-23	2005-07-14	Arbor Vita Corporation	Antibodies for oncogenic strains of hpv and methods of their use
US7098040B2 (en) *	2003-12-23	2006-08-29	Kimberly-Clark Worldwide, Inc.	Self-contained swab-based diagnostic systems
US7863053B2 (en) *	2003-12-23	2011-01-04	Kimberly-Clark Worldwide, Inc.	Swab-based diagnostic systems
US7718408B2 (en) *	2003-12-24	2010-05-18	Danisco A/S	Method
GB0716126D0 (en) *	2007-08-17	2007-09-26	Danisco	Process
WO2008090395A1 (en)	2007-01-25	2008-07-31	Danisco A/S	Production of a lipid acyltransferase from transformed bacillus licheniformis cells
EP2119771B1 (de)	2003-12-24	2018-08-22	DuPont Nutrition Biosciences ApS	Proteine
US7150995B2 (en)	2004-01-16	2006-12-19	Metrika, Inc.	Methods and systems for point of care bodily fluid analysis
US20050186646A1 (en) *	2004-01-26	2005-08-25	Cruz Miguel A.	Rapid assay to detect ADAMTS-13 activity
US7638093B2 (en) *	2004-01-28	2009-12-29	Dnt Scientific Research, Llc	Interrupted flow rapid confirmatory immunological testing device and method
EP1733235A1 (de) *	2004-01-29	2006-12-20	DSM IP Assets B.V.	Verbesserter seitenstrom-bindungstest
EP1730173A4 (de) *	2004-02-18	2008-10-08	Merck & Co Inc	Nukleinsäuremoleküle, codierend für neue, durch niedrige spannungen aktivierte, als alpha 1h bezeichnete calciumkanalproteine aus der maus, codierte proteine und verfahren zu deren anwendung
GB0403864D0 (en)	2004-02-20	2004-03-24	Ucl Ventures	Modulator
EP2208797A3 (de)	2004-03-01	2010-11-24	Applied Biosystems, LLC	Verfahren, Zusammensetzungen und Kits für Polynukleotidamplifikation
DK1734970T3 (en)	2004-03-12	2015-02-16	Intercept Pharmaceuticals Inc	Treatment of fibrosis using FXR ligands
GB0405637D0 (en)	2004-03-12	2004-04-21	Danisco	Protein
JP2007530946A (ja) *	2004-03-23	2007-11-01	クイデルコーポレイション	ハイブリッド相ラテラルフロー・アッセイ
EP2207033B1 (de)	2004-04-15	2014-06-18	University of Florida Research Foundation, Inc.	Neuralproteine als Biomarker für Verletzungen des Nervensystems und anderen neuralen Störungen
NZ550145A (en)	2004-04-23	2009-07-31	Pharmacia & Upjohn Co Llc	Cellular permissivity factor for viruses, and uses thereof
US7815854B2 (en)	2004-04-30	2010-10-19	Kimberly-Clark Worldwide, Inc.	Electroluminescent illumination source for optical detection systems
US7796266B2 (en)	2004-04-30	2010-09-14	Kimberly-Clark Worldwide, Inc.	Optical detection system using electromagnetic radiation to detect presence or quantity of analyte
US7939251B2 (en)	2004-05-06	2011-05-10	Roche Molecular Systems, Inc.	SENP1 as a marker for cancer
EP2400030B1 (de)	2004-05-18	2016-01-20	The Board of Trustees of the Leland Stanford Junior University	Detektion von Proteintranslokation durch Beta-Galactosidase-Reporter-Fragmentkomplementierung
WO2005118864A2 (en)	2004-05-28	2005-12-15	Agensys, Inc.	Antibodies and related molecules that bind to psca proteins
ATE428931T1 (de)	2004-06-03	2009-05-15	Meso Scale Technologies Llc	Verfahren zur durchführung von vollbluttests
CN101133157A (zh)	2004-06-03	2008-02-27	阿什洛米克斯控股有限公司	诊断应激的药物和方法
CA2571243A1 (en)	2004-06-21	2006-01-05	The Board Of Trustees Of The Leland Stanford Junior University	Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder
US8034553B2 (en)	2004-06-24	2011-10-11	Kimberly-Clark Worldwide, Inc.	Biomarkers for wound healing
US7521226B2 (en)	2004-06-30	2009-04-21	Kimberly-Clark Worldwide, Inc.	One-step enzymatic and amine detection technique
US7763454B2 (en)	2004-07-09	2010-07-27	Church & Dwight Co., Inc.	Electronic analyte assaying device
EP2275522A3 (de)	2004-07-16	2011-09-21	Danisco A/S	Enzymatisches Ölentschleimungsverfahren
WO2006007664A1 (en) *	2004-07-22	2006-01-26	Genomics Research Partners Pty Ltd	Agents and methods for diagnosing osteoarthritis
EP1789437A4 (de) *	2004-07-30	2008-11-05	Sinai School Medicine	Npc1l1 und npc1l1-inhibitoren und verfahren zu deren anwendung
EP1784510A4 (de) *	2004-08-02	2010-08-04	Janssen Pharmaceutica Nv	Irak1c-spleissvariante und deren verwendung
US20060073168A1 (en) *	2004-08-11	2006-04-06	Stephens David S	Neisseria meningitidis serogroup a capsular polysaccharide acetyltransferase, methods and compositions
US7598080B2 (en)	2004-08-20	2009-10-06	Carl Deirmengian	Diagnostic assay for source of inflammation
US7893197B2 (en) *	2004-08-25	2011-02-22	Janssen Pharmaceutica N.V.	Relaxin-3 chimeric polypeptides and their preparation and use
AU2005276145C1 (en)	2004-08-26	2011-01-06	Engeneic Molecular Delivery Pty Ltd	Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells
ES2345993T3 (es)	2004-09-14	2010-10-07	The Regents Of The University Of Colorado, A Body Corporate	Metodo para el tratamiento con bucindolol basado en direccionamiento genetico.
CA2580606A1 (en)	2004-09-18	2006-03-30	University Of Maryland, Baltimore	Therapeutic agents targeting the ncca-atp channel and methods of use thereof
JP5307397B2 (ja)	2004-09-18	2013-10-02	ユニバーシティオブメリーランド，ボルチモア	ＮＣＣａ−ＡＴＰチャネルを標的とする治療剤およびその使用方法
US8685711B2 (en)	2004-09-28	2014-04-01	Singulex, Inc.	Methods and compositions for highly sensitive detection of molecules
US9040305B2 (en)	2004-09-28	2015-05-26	Singulex, Inc.	Method of analysis for determining a specific protein in blood samples using fluorescence spectrometry
GB0422052D0 (en)	2004-10-04	2004-11-03	Dansico As	Enzymes
US7390489B2 (en)	2004-10-08	2008-06-24	Komed Co., Ltd.	Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
GB0423139D0 (en) *	2004-10-18	2004-11-17	Danisco	Enzymes
WO2006047417A2 (en)	2004-10-21	2006-05-04	University Of Florida Research Foundation, Inc.	Detection of cannabinoid receptor biomarkers and uses thereof
DK2586456T3 (en)	2004-10-29	2016-03-21	Ratiopharm Gmbh	Conversion and glycopegylation of fibroblast growth factor (FGF)
JP5525689B2 (ja) *	2004-11-02	2014-06-18	ザガバメントオブザユナイテッドステイツオブアメリカアズリプレゼンティッドバイザセクレタリーデパートメントオブヘルスアンドヒューマンサービシーズ	過剰増殖性障害を処置するための組成物および方法
ATE520029T1 (de) *	2004-11-05	2011-08-15	Hoffmann La Roche	Biochemisches gerät und nachweisverfahren
GB0424940D0 (en)	2004-11-11	2004-12-15	Danisco	Transcription factors
JP2008520583A (ja) *	2004-11-15	2008-06-19	マウントシナイスクールオブメディスンオブニューヨークユニバーシティー	Ｗｎｔ自己分泌シグナル伝達を改変するための組成物および方法
ATE482288T1 (de)	2004-11-18	2010-10-15	Eppendorf Array Technologies	Echtzeit-pcr von zielen auf einem mikroarray
US7465587B2 (en) *	2004-12-03	2008-12-16	Genzyme Corporation	Diagnostic assay device
MX2007006640A (es)	2004-12-03	2007-06-19	Schering Corp	Biomarcadores para la preseleccion de pacientes para la terapia con anti-receptor 1 del factor de crecimiento similar a la insulina.
US20060205012A1 (en) *	2004-12-09	2006-09-14	Meso Scale Technologies, Llc	Diagnostic test
US7387890B2 (en) *	2004-12-16	2008-06-17	Chembio Diagnostic Systems, Inc.	Immunoassay devices and use thereof
US7504769B2 (en) *	2004-12-16	2009-03-17	E. I. Du Pont De Nemours + Company	Aromatic chalcogen compounds and their use
EP1833964B1 (de)	2004-12-17	2013-05-22	Monash University	Regulation der metalloproteasespaltung von zelloberflächenproteinen durch adam10
US7682817B2 (en) *	2004-12-23	2010-03-23	Kimberly-Clark Worldwide, Inc.	Microfluidic assay devices
US8697674B2 (en)	2004-12-29	2014-04-15	Naturon, Inc.	Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
JP4004505B2 (ja) *	2005-01-11	2007-11-07	富士フイルム株式会社	流路部材及びセンサユニット
EP1853914B1 (de)	2005-01-25	2015-04-22	The Johns Hopkins University	Plasmodium-diagnosetest
AU2006332045A1 (en)	2005-01-27	2007-08-16	The Regents Of The University Of California	Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
US20060292700A1 (en) *	2005-06-22	2006-12-28	Naishu Wang	Diffused interrupted lateral flow immunoassay device and method
WO2006086242A2 (en)	2005-02-07	2006-08-17	Genenews, Inc.	Mild osteoarthritis biomarkers and uses thereof
GB0503546D0 (en) *	2005-02-21	2005-03-30	Hellenic Pasteur Inst	Antibody
WO2006098804A2 (en)	2005-03-11	2006-09-21	Chembio Diagnostic Systems, Inc.	Dual path immunoassay device
US7189522B2 (en)	2005-03-11	2007-03-13	Chembio Diagnostic Systems, Inc.	Dual path immunoassay device
US7939342B2 (en)	2005-03-30	2011-05-10	Kimberly-Clark Worldwide, Inc.	Diagnostic test kits employing an internal calibration system
AU2006230563B8 (en)	2005-03-31	2010-06-17	Agensys, Inc.	Antibodies and related molecules that bind to 161P2F10B proteins
US8048638B2 (en) *	2005-04-01	2011-11-01	University Of Florida Research Foundation, Inc.	Biomarkers of liver injury
CA2635198C (en)	2005-04-01	2019-11-12	University Of Florida Research Foundation, Inc	Biomarkers of liver injury
EP3796003A1 (de)	2005-04-04	2021-03-24	Biogen MA Inc.	Verfahren zur bewertung einer immunreaktion auf ein therapeutisches mittel
US20070154992A1 (en)	2005-04-08	2007-07-05	Neose Technologies, Inc.	Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
JP5537804B2 (ja)	2005-04-18	2014-07-02	ミトミクスインコーポレーテッド	日光曝露、前立腺癌および他の癌の検出用の診断ツールとしての、ミトコンドリアの突然変異および再配置
US20130022979A1 (en)	2005-04-18	2013-01-24	Genesis Genomics Inc.	3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER
US7439079B2 (en) *	2005-04-29	2008-10-21	Kimberly-Clark Worldwide, Inc.	Assay devices having detection capabilities within the hook effect region
US7858384B2 (en)	2005-04-29	2010-12-28	Kimberly-Clark Worldwide, Inc.	Flow control technique for assay devices
US7803319B2 (en)	2005-04-29	2010-09-28	Kimberly-Clark Worldwide, Inc.	Metering technique for lateral flow assay devices
US20070021433A1 (en)	2005-06-03	2007-01-25	Jian-Qiang Fan	Pharmacological chaperones for treating obesity
DK2500439T4 (da)	2005-06-20	2017-11-13	Advanced Cell Diagnostics Inc	Kits og produkter til detektering af nukleinsyrer i individuelle celler og til identifikation af sjældne celler fra store heterogene cellepopulationer
WO2007006091A1 (en)	2005-07-07	2007-01-18	Athlomics Pty Ltd	Polynucleotide marker genes and their expression, for diagnosis of endotoxemia
US20070015166A1 (en) *	2005-07-14	2007-01-18	Nilsen Thor W	Lateral flow methods and devices for detection of nucleic acid binding proteins
CA2615460A1 (en) *	2005-08-08	2007-02-15	Onconon, Llc	Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility
US20070042504A1 (en) *	2005-08-22	2007-02-22	Yimin Yu	Method for determining substance or substances in liquid sample
LT1931710T (lt)	2005-08-31	2017-03-27	Merck Sharp & Dohme Corp.	Rekombinantiniai anti-il-23 antikūnai
US7829347B2 (en) *	2005-08-31	2010-11-09	Kimberly-Clark Worldwide, Inc.	Diagnostic test kits with improved detection accuracy
US8193328B2 (en) *	2005-09-08	2012-06-05	Philadelphia Health & Education Corporation	Identification of modulators of serine protease inhibitor Kazal and their use as anti-cancer and anti-viral agents
US7608395B2 (en)	2005-09-15	2009-10-27	Baylor Research Institute	Systemic lupus erythematosus diagnostic assay
WO2007041340A2 (en) *	2005-09-30	2007-04-12	The Trustees Of Columbia University In The City Of New York	Microfluidic cells with parallel arrays of individual dna molecules
IL172297A (en)	2005-10-03	2016-03-31	Compugen Ltd	Soluble vegfr-1 variants for the diagnosis of preeclampsia
WO2007047408A2 (en) *	2005-10-12	2007-04-26	Pathologica, Llc.	Promac signature application
US7910381B2 (en) *	2005-10-13	2011-03-22	BioAssay Works	Immuno gold lateral flow assay
US7344893B2 (en) *	2005-10-13	2008-03-18	Auric Enterprises, Llc	Immuno-gold lateral flow assay
US8153444B2 (en) *	2005-10-13	2012-04-10	Auric Enterprises, Llc	Immuno gold lateral flow assay
WO2007048092A2 (en) *	2005-10-17	2007-04-26	Spidertech, A Division Of Stoecker & Associates, A Subsidiary Of The Dermatology Center, Llc	Immunoassay for venom detection including noninvasive sample collection
US8249814B2 (en)	2005-10-21	2012-08-21	Genenews Inc.	Method, computer readable medium, and system for determining a probability of colorectal cancer in a test subject
MX2008005405A (es) *	2005-10-28	2008-09-11	Florida Internat University Bo	Anticuerpos quimericos equinos: humanos.
CA2628238A1 (en)	2005-11-07	2007-05-18	The Scripps Research Institute	Compositions and methods for controlling tissue factor signaling specificity
AU2006315562C1 (en)	2005-11-12	2013-10-03	The Board Of Trustees Of The Leland Stanford Junior University	Methods for treating depression using NCAM peptide mimetics
WO2007061684A1 (en)	2005-11-18	2007-05-31	Board Of Regents, The University Of Texas System	Quantification of fusion proteins and their activity from chromosomal translocation
US7763453B2 (en)	2005-11-30	2010-07-27	Micronics, Inc.	Microfluidic mixing and analytic apparatus
US9056291B2 (en)	2005-11-30	2015-06-16	Micronics, Inc.	Microfluidic reactor system
RU2008127252A (ru)	2005-12-08	2010-01-20	Новартис АГ (CH)	Эффекты ингибиторов fgfr3 на транскрипцию генов
US20070134814A1 (en) *	2005-12-09	2007-06-14	Kajander E O	Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
US7279136B2 (en)	2005-12-13	2007-10-09	Takeuchi James M	Metering technique for lateral flow assay devices
US7745158B2 (en) *	2005-12-14	2010-06-29	Kimberly-Clark Worldwide, Inc.	Detection of secreted aspartyl proteases from Candida species
US7618810B2 (en)	2005-12-14	2009-11-17	Kimberly-Clark Worldwide, Inc.	Metering strip and method for lateral flow assay devices
EP2674440B1 (de)	2005-12-16	2019-07-03	IBC Pharmaceuticals, Inc.	Polyvalente bioaktive anordnungen auf immunglobulinbasis
CA2634130C (en)	2005-12-21	2021-08-03	Meso Scale Technologies, Llc	Assay apparatuses, methods and reagents
US9347945B2 (en)	2005-12-22	2016-05-24	Abbott Molecular Inc.	Methods and marker combinations for screening for predisposition to lung cancer
WO2007076439A2 (en)	2005-12-22	2007-07-05	Abbott Laboratories	Methods and marker combinations for screening for predisposition to lung cancer
US20090053694A1 (en) *	2005-12-26	2009-02-26	Kriksunov Leo B	Photochemically Amplified Bioassay
US7465544B2 (en) *	2006-01-11	2008-12-16	Wisconsin Alumni Research Foundation	Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use
EP1973945A4 (de)	2006-01-16	2009-11-18	Compugen Ltd	Neue nukleotid- und aminosäuresequenzen und verfahren zu deren anwendung in der diagnose
US7794656B2 (en)	2006-01-23	2010-09-14	Quidel Corporation	Device for handling and analysis of a biological sample
US7871568B2 (en)	2006-01-23	2011-01-18	Quidel Corporation	Rapid test apparatus
PT1981902E (pt)	2006-01-27	2015-11-02	Biogen Ma Inc	Antagonistas dos recetores nogo
WO2007088051A2 (en)	2006-01-31	2007-08-09	Bayer Schering Pharma Aktiengesellschaft	Modulation of mdl-1 activity for treatment of inflammatory disease
ATE551067T1 (de)	2006-02-03	2012-04-15	Crc For Asthma And Airways Ltd	Tumstatin zur behandlung von erkrankungen die mit der neumodellierung von atemwegsgewebe zusammenhängen
MX360595B (es)	2006-02-08	2018-11-09	Genzyme Corp	Terapia génica para la enfermedad de niemann-pick de tipo a.
US20070224701A1 (en) *	2006-02-16	2007-09-27	Becton, Dickinson And Company	Combination vertical and lateral flow immunoassay device
EP1988921A4 (de)	2006-02-28	2010-02-10	Elan Pharm Inc	Verfahren zur behandlung von entzündungs- und autoimmunerkrankungen mit natalizumab
WO2007103112A2 (en)	2006-03-03	2007-09-13	Elan Pharmaceuticals, Inc.	Methods of treating inflammatory and autoimmune diseases with natalizumab
WO2007109733A2 (en)	2006-03-21	2007-09-27	The Johns Hopkins University	Diagnostic and prognostic markers and treatment strategies for multiple sclerosis
US20070232556A1 (en) *	2006-03-31	2007-10-04	Montine Thomas J	Methods and compositions for the treatment of neurological diseases and disorders
EP3168618B1 (de)	2006-04-04	2018-11-21	Singulex, Inc.	Hochempfindliche verfahren zur troponinanalyse
EP3156799B1 (de)	2006-04-04	2024-01-24	Novilux, LLC	Analysator und verfahren zur hochempfindlichen detektion von analyten
KR20090029184A (ko) *	2006-04-07	2009-03-20	더 가브먼트 오브 더 유나이티드 스테이츠 오브 아메리카, 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈	항체 조성물 및 신생물성 질병의 치료 방법
KR101387563B1 (ko)	2006-04-21	2014-04-25	세노믹스, 인코포레이티드	고효능의 조미용 향료를 포함하는 식품 조성물 및 이의 제조 방법
FR2900341B1 (fr)	2006-04-27	2012-09-14	Centre Nat Rech Scient	Utilisation de ligands synthetiques multivalents de la nucleoline de surface pour le traitement du cancer
KR20090034811A (ko) *	2006-05-09	2009-04-08	무스크 파운데이션 포 리서치 디벨롭먼트	프로테아제 및 프로테아제 저해제 혈장 프로파일링에 의해 확장기 심부전을 검출하는 방법
AU2007265628B2 (en) *	2006-06-23	2012-12-06	Perkinelmer Health Sciences, Inc.	Methods and devices for microfluidic point-of-care immunoassays
CA2656347A1 (en)	2006-07-03	2008-01-10	Charles David Adair	Composition for modulating the expression of cell adhesion molecules
RU2009104460A (ru) *	2006-07-11	2010-08-20	Маск Фаундейшн Фор Рисерч Дивелопмент (Us)	Прогнозирование сердечной недостаточности после инфаркта миокарда по профилю протеаз и ингибиторов протеаз
US20080026394A1 (en) *	2006-07-11	2008-01-31	Antara Biosciences Inc.	Methods of detecting one or more cancer markers
MX2009000395A (es)	2006-07-14	2009-01-29	Chemocentryx Inc	Triazolil fenil bencenosulfonamidas.
JP2009545320A (ja) *	2006-08-04	2009-12-24	ザジェネラルホスピタルコーポレイション	副甲状腺ホルモン（ｐｔｈ）のポリペプチド誘導体
EP2053961A4 (de) *	2006-08-09	2013-05-01	Biogen Idec Inc	Verfahren zur verbreitung eines wirkstoffs
JP2008043332A (ja)	2006-08-17	2008-02-28	Panomics Inc	組織スライドからの核酸定量
WO2008023840A2 (en)	2006-08-25	2008-02-28	Oncotherapy Science, Inc.	Prognostic markers and therapeutic targets for lung cancer
JP2008111824A (ja) *	2006-09-01	2008-05-15	Nox Technologies Inc	腫瘍特異的ｔＮＯＸアイソフォーム及び方法
US7951776B2 (en)	2006-09-01	2011-05-31	American Type Culture Collection	Methods for treatment of type 1 diabetes
US7985542B2 (en) *	2006-09-07	2011-07-26	Institut Pasteur	Genomic morse code
US7569396B1 (en)	2006-09-08	2009-08-04	Purplecow Llc	Caffeine detection using internally referenced competitive assays
EP2469283B1 (de)	2006-09-08	2014-01-15	The Chancellor, Masters and Scholars of the University of Oxford	Klinische Diagnose von Leberfibrose mithilfe APOL1 als menschlichen Serumprotein-Biomarker
US8055034B2 (en)	2006-09-13	2011-11-08	Fluidigm Corporation	Methods and systems for image processing of microfluidic devices
US8050516B2 (en) *	2006-09-13	2011-11-01	Fluidigm Corporation	Methods and systems for determining a baseline during image processing
WO2008043566A2 (en)	2006-10-11	2008-04-17	Janssen Pharmaceutica N.V.	Compositions and methods for treating and diagnosing irritable bowel syndrome
EP1912067A1 (de) *	2006-10-12	2008-04-16	Eppendorf Array Technologies S.A.	Verfahren zur Quantifizierung eines Analyten in einer biologischen Probe durch Microarray-Chips
EP2426199A3 (de)	2006-10-20	2012-08-22	Danisco US Inc.	Polyoloxidasen
US20080305512A1 (en) *	2006-10-26	2008-12-11	Mattingly Phillip G	Assay for cardiac troponin autoantibodies
EP2097750A2 (de) *	2006-10-26	2009-09-09	Abbott Laboratories	Immunoassay aus analyten in proben mit endogenen antikörpern gegen analyte
US7776605B2 (en)	2006-10-26	2010-08-17	Abbott Laboratories	Assay for cardiac troponin autoantibodies
JP2010507384A (ja)	2006-10-27	2010-03-11	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	キナーゼ阻害剤のプロファイリング方法
WO2008066655A2 (en)	2006-11-02	2008-06-05	Yale University	Assessment of oocyte competence
US8293684B2 (en) *	2006-11-29	2012-10-23	Exiqon	Locked nucleic acid reagents for labelling nucleic acids
US8473216B2 (en) *	2006-11-30	2013-06-25	Fluidigm Corporation	Method and program for performing baseline correction of amplification curves in a PCR experiment
EP2102239B1 (de)	2006-11-30	2012-04-25	Research Development Foundation	Verbesserte immunglobulin-bibliotheken
US20080138842A1 (en) *	2006-12-11	2008-06-12	Hans Boehringer	Indirect lateral flow sandwich assay
KR20090088950A (ko)	2006-12-14	2009-08-20	쉐링 코포레이션	가공된 항-ｔｓｌｐ 항체
US8377379B2 (en)	2006-12-15	2013-02-19	Kimberly-Clark Worldwide, Inc.	Lateral flow assay device
US7935538B2 (en)	2006-12-15	2011-05-03	Kimberly-Clark Worldwide, Inc.	Indicator immobilization on assay devices
US8506499B2 (en) *	2007-01-04	2013-08-13	Musc Foundation For Research Development	Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling
JP5690068B2 (ja) *	2007-01-11	2015-03-25	エラスムスユニバーシティメディカルセンター	環状染色体コンホメーション捕捉（４ｃ）
CA2674949A1 (en)	2007-01-12	2008-07-24	J. Marc Simard	Targeting ncca-atp channel for organ protection following ischemic episode
BRPI0806437A2 (pt)	2007-01-26	2011-09-06	Univ Lousville Res Foundation Inc	métodos de detecção de auto-anticorpos para diagnóstico e caracterização de distúrbio
US8143046B2 (en)	2007-02-07	2012-03-27	Danisco Us Inc., Genencor Division	Variant Buttiauxella sp. phytases having altered properties
KR100855299B1 (ko) *	2007-02-16	2008-08-29	건국대학교 산학협력단	인간 ｉｌ-32 특이 항원결정기를 갖는 단일클론항체,특이항체분비 융합 세포주 및 항체들을 이용한 ｉｌ-32측정법
ES2708988T3 (es)	2007-02-23	2019-04-12	Merck Sharp & Dohme	Anticuerpos anti-IL-23p19 obtenidos por ingeniería genética
CN101663320A (zh)	2007-02-23	2010-03-03	先灵公司	工程改造的抗IL-23p19抗体
KR20100014568A (ko)	2007-02-28	2010-02-10	쉐링 코포레이션	가공된 항-ｉｌ-23ｒ 항체
US7776618B2 (en)	2007-03-01	2010-08-17	Church & Dwight Co., Inc.	Diagnostic detection device
US20100216654A1 (en)	2007-03-12	2010-08-26	Miraculins, Inc.	Biomarkers of prostate cancer and uses thereof
WO2008118324A2 (en)	2007-03-26	2008-10-02	Macrogenics, Inc.	Composition and method of treating cancer with an anti-uroplakin ib antibody
WO2009005552A2 (en) *	2007-03-29	2009-01-08	Epitype Corporation	Methods and compositions for multivalent binding and methods for manufacture of rapid diagnostic tests
LT2865755T (lt)	2007-03-30	2017-07-25	Engeneic Molecular Delivery Pty Ltd	Iš bakterijų gautos, sveikos miniląstelės, apimančios reguliacinę rnr
ATE534753T1 (de)	2007-04-06	2011-12-15	Becton Dickinson Co	Zusammensetzungen und verfahren zur identifikation eines carbapenemase-gens
EP2076289B1 (de)	2007-04-13	2014-11-12	Dana-Farber Cancer Institute, Inc.	Methoden zur behandlung von erbb-therapie resistenten krebs
US8003314B2 (en)	2007-04-16	2011-08-23	Diagnostic Hybrids, Inc.	Methods for direct fluorescent antibody virus detection in liquids
CA2684998A1 (en)	2007-04-30	2009-01-29	Nanogen, Inc.	Multianalyte assay
CA2685675C (en)	2007-05-01	2016-02-16	Research Development Foundation	Immunoglobulin fc libraries
WO2009009215A2 (en) *	2007-05-02	2009-01-15	Emory University	Enhancement of glycoprotein incorporation into virus-like particles
BRPI0812400A2 (pt)	2007-06-05	2014-10-29	Univ Yale	Unidade, hibridoma, composição farmacêutica, método para identificar uma unidade, anticorpo isolado a uma unidade de ligação de antígeno do mesmo, molécula peptídica, e, uso da unidade.
CN103254308B (zh)	2007-06-15	2015-01-21	厦门大学	H5亚型禽流感病毒血凝素蛋白的单克隆抗体或其结合活性片段及其用途
US7776877B2 (en) *	2007-06-22	2010-08-17	Chemocentryx, Inc.	N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
US9102754B2 (en) *	2007-06-28	2015-08-11	University Of Saskatchewan	Immunomodulatory compositions and methods for treating disease with modified host defense peptides
ES2383568T3 (es) *	2007-07-12	2012-06-22	Chemocentryx, Inc.	Heteroaril piridil y fenil bencenosulfonamidas condensadas como moduladores de CCR2 para el tratamiento de la inflamación
US8293685B2 (en)	2007-07-26	2012-10-23	The Regents Of The University Of California	Methods for enhancing bacterial cell display of proteins and peptides
MX346714B (es) *	2007-08-01	2017-03-24	The General Hospital Corp *	Metodos de analisis y seleccion usando receptores acoplados a proteina g y composiciones relacionadas.
US8715743B2 (en)	2007-08-03	2014-05-06	Musc Foundation For Research Development	Human monoclonal antibodies and methods for producing the same
CA2694832A1 (en)	2007-08-06	2009-02-12	Orion Genomics Llc	Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the igf2 gene
AU2008296733B2 (en)	2007-08-08	2013-07-11	The Board Of Regents Of The University Of Texas System	VEGFR-1/NRP-1 targeting peptides
WO2009023676A1 (en)	2007-08-12	2009-02-19	Integrated Dna Technologies, Inc.	Microarray system with improved sequence specificity
US20090136916A1 (en) *	2007-08-13	2009-05-28	Trustees Of Tufts College	Methods and microarrays for detecting enteric viruses
US20090087860A1 (en) *	2007-08-24	2009-04-02	Todd John A	Highly sensitive system and methods for analysis of prostate specific antigen (psa)
US8415455B2 (en)	2007-09-04	2013-04-09	Compugen Ltd	Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
US8053198B2 (en) *	2007-09-14	2011-11-08	Meso Scale Technologies, Llc	Diagnostic methods
WO2009048530A2 (en)	2007-10-05	2009-04-16	Panomics, Inc.	Highly multiplexed particle-based assays
US8535617B2 (en) *	2007-11-30	2013-09-17	Kimberly-Clark Worldwide, Inc.	Blood cell barrier for a lateral flow device
US20090155753A1 (en) *	2007-12-14	2009-06-18	Kimberly-Clark Worldwide, Inc.	Behavior Tracking with Tracking Pods
US9103796B2 (en) *	2007-12-14	2015-08-11	Kimberly-Clark Worldwide, Inc.	Multi-layered devices for analyte detection
JP2011508219A (ja)	2007-12-19	2011-03-10	シンギュレックス・インコーポレイテッド	単一分子検出走査分析器およびその使用方法
KR101588736B1 (ko)	2008-01-10	2016-01-26	리서치 디벨롭먼트 파운데이션	얼리키아 샤피엔시스에 대한 백신 및 진단제
AU2009208607B2 (en) *	2008-01-31	2013-08-01	Compugen Ltd.	Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
US20090196852A1 (en) *	2008-02-04	2009-08-06	Watkinson D Tobin	Compositions and methods for diagnosing and treating immune disorders
EP3272353A1 (de)	2008-02-07	2018-01-24	Cornell University	Verfahren zur vorbeugung oder behandlung von insulinresistenz
US20090311695A1 (en) *	2008-03-12	2009-12-17	Talat Nasim	Method
AU2009258038A1 (en)	2008-03-14	2009-12-17	Eastern Virginia Medical School	Imaging mass spectrometry for improved prostate cancer diagnostics
US8993231B2 (en) *	2008-03-18	2015-03-31	Marshall University Research Corporation	Methods for stem cell production and therapy
CN107011428B (zh)	2008-03-28	2022-02-25	Mdna生命科学有限公司	异常线粒体dna、相关的融合转录物及其杂交探针
EP2107125A1 (de)	2008-03-31	2009-10-07	Eppendorf Array Technologies SA (EAT)	Echtzeit-PCR von Targets auf einem Mikroarray
CA2720365C (en)	2008-04-02	2019-01-15	Macrogenics, Inc.	Bcr-complex-specific antibodies and methods of using same
CN102046195A (zh)	2008-04-02	2011-05-04	宏观基因有限公司	HER2/neu-特异性抗体和其使用方法
JP2011518323A (ja)	2008-04-11	2011-06-23	メソスケールテクノロジーズエルエルシー	アッセイ装置、方法、および試薬
GB0807161D0 (en) *	2008-04-18	2008-05-21	Danisco	Process
KR20110011635A (ko) *	2008-04-23	2011-02-08	루미넥스 코포레이션	생물학적 기원의 출발 물질에서 발견된 복수의 분석물에 대한 기준의 생성 방법
JP2012500620A (ja)	2008-04-24	2012-01-12	ザトラスティーズオブコロンビアユニバーシティーインザシティーオブニューヨーク	Ｄｎａ分子組織化のための幾何学的パターンおよび脂質二重層、ならびにその使用
CN102083996A (zh)	2008-04-30	2011-06-01	丹尼斯科公司	氧化方法
JP5548866B2 (ja) *	2008-05-22	2014-07-16	サントルナスィオナルドラルシェルシュスィアンティフィク（セ．エン．エル．エス．）	治療効果の改善のための新規の光学的に純粋な化合物
WO2010033279A2 (en)	2008-06-04	2010-03-25	Macrogenics, Inc.	Antibodies with altered binding to fcrn and methods of using same
WO2010011860A1 (en) *	2008-07-23	2010-01-28	Diabetomics, Llc	Methods for detecting pre-diabetes and diabetes
US20100021472A1 (en) *	2008-07-25	2010-01-28	Geetha Srikrishna	Methods for diagnosing and treating cancer
CA2734892A1 (en)	2008-08-18	2010-02-25	Seoul National University Industry Foundation	Method for controlling cancer metastasis or cancer cell migration by modulating the cellular level of lysyl trna synthetase
GB2464183A (en) *	2008-09-19	2010-04-14	Singulex Inc	Sandwich assay
US9434985B2 (en)	2008-09-25	2016-09-06	University Of Massachusetts	Methods of identifying interactions between genomic loci
US8101813B2 (en) *	2008-10-30	2012-01-24	Kimberly-Clark Worldwide, Inc.	Training progress indicator
JP5805538B2 (ja)	2008-11-07	2015-11-04	リサーチディベロップメントファウンデーション	Ｃｒｉｐｔｏ／ＧＳＰ７８複合体形成およびシグナル伝達を阻害するための組成物および方法
WO2010061393A1 (en)	2008-11-30	2010-06-03	Compugen Ltd.	He4 variant nucleotide and amino acid sequences, and methods of use thereof
US20110287088A1 (en)	2008-12-03	2011-11-24	Research Development Foundation	Modulation of olfml-3 mediated angiogenesis
EP2194381B1 (de)	2008-12-03	2015-12-02	Roche Diagnostics GmbH	Testelement mit kombinierter Kontroll- und Kalibrationszone
US8431775B2 (en)	2008-12-04	2013-04-30	Pioneer Hi Bred International Inc	Methods and compositions for enhanced yield by targeted expression of knotted1
CA2745904C (en)	2008-12-05	2014-07-08	Abraxis Bioscience Llc	Sparc binding peptides and uses thereof
CA2745492A1 (en)	2008-12-08	2010-06-17	Compugen Ltd.	A polyclonal or monoclonal antibody or antibody binding fragment that binds to a tmem154 polypeptide
US20120003664A1 (en)	2008-12-09	2012-01-05	Uffe Lovborg	Method for evaluating pre-treatment
WO2010068757A1 (en)	2008-12-12	2010-06-17	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Compositions and methods useful for detecting and treating diseases associated with 16p chromosomal disruptions
US8962341B2 (en)	2008-12-12	2015-02-24	The Commonwealth Medical College	Cell-based detection of APF through its interaction with CKAP4 for diagnosis of interstitial cystitis
US8422740B2 (en)	2009-01-15	2013-04-16	Scott Dylewski	Methods for determining a liquid front position on a test strip
US8692873B2 (en)	2009-01-15	2014-04-08	Alverix, Inc.	Video-frame data receiver with low frame capture rate
ES2544265T3 (es)	2009-02-11	2015-08-28	Orion Genomics, Llc	Combinaciones de polimorfismos para determinar la expresión específica de alelo de IGF2
JP2012517238A (ja)	2009-02-11	2012-08-02	カリスエムピーアイインコーポレイテッド	腫瘍の分子プロファイリング法
DE102009010563A1 (de)	2009-02-16	2010-08-26	Matthias W. Engel	Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten
US20110306069A1 (en)	2009-02-19	2011-12-15	Qingyu Wu	Corin As A Marker For Heart Failure
US20100240065A1 (en) *	2009-03-18	2010-09-23	Boehringer Ingelheim International Gmbh	Prolyl Hydroxylase Compositions and Methods of Use Thereof
US8481698B2 (en) *	2009-03-19	2013-07-09	The President And Fellows Of Harvard College	Parallel proximity ligation event analysis
RU2011137486A (ru)	2009-03-27	2013-05-10	Митомикс Инк.	Аберрантная митохондриальная днк, ассоциированные с ней слитые транскрипты, продукты трансляции и гибрадизационные зонды
TW201039841A (en)	2009-03-27	2010-11-16	Gojo Ind Inc	Compositions and methods for screening and using compounds antagonizing spore-surface interactions
US20100261292A1 (en)	2009-04-10	2010-10-14	Meso Scale Technologies, Llc	Methods for Conducting Assays
AU2010239131A1 (en)	2009-04-21	2011-11-17	Genetic Technologies Limited	Methods for obtaining fetal genetic material
GB0908770D0 (en)	2009-04-24	2009-07-01	Danisco	Method
US20120046197A1 (en)	2009-05-01	2012-02-23	Meso Scale Technologies, Llc	Biomarkers of therapeutic responsiveness
EP2425253B1 (de)	2009-05-01	2017-03-22	Dako Denmark A/S	Neuer antikörper-cocktail
US8168396B2 (en)	2009-05-11	2012-05-01	Diabetomics, Llc	Methods for detecting pre-diabetes and diabetes using differential protein glycosylation
US20120058916A1 (en)	2009-05-13	2012-03-08	Meso Scale Technologies, Llc.	Diagnostic methods for liver disorders
ES2897692T3 (es) *	2009-05-14	2022-03-02	Shox Science Ltd	Diagnóstico clínico de la fibrosis hepática mediante un nuevo grupo de biomarcadores de proteínas plasmáticas humanas poco abundantes
US20120058222A1 (en)	2009-05-19	2012-03-08	Danisco A/S	Use
US20120128673A1 (en)	2009-05-20	2012-05-24	Schering Corporation	Modulation of pilr receptors to treat microbial infections
JP5828837B2 (ja)	2009-06-02	2015-12-09	ザボードオブリージェンツオブザユニバーシティーオブテキサスシステム	神経変性疾患を有する被験者において抗体により認識される小分子の同定
US8802427B2 (en) *	2009-06-09	2014-08-12	Church & Dwight Co., Inc.	Female fertility test
EP2446027A1 (de)	2009-06-25	2012-05-02	Danisco A/S	Protein
CN107090031A (zh)	2009-07-17	2017-08-25	生物蛋白有限公司	在生产宿主中同时整合抗体/蛋白的性能和表达的筛选和演化的方法
WO2011017094A2 (en)	2009-07-27	2011-02-10	Ian Chamberlin	Assay apparatuses, consumables and methods
WO2011012672A1 (en)	2009-07-29	2011-02-03	Pharnext	New diagnostic tools for alzheimer disease
KR20170119746A (ko)	2009-09-03	2017-10-27	머크 샤프 앤드 돔 코포레이션	항-ｇｉｔｒ 항체
US8900850B2 (en) *	2009-09-17	2014-12-02	Michael J. Lane	Lateral flow based methods and assays for rapid and inexpensive diagnostic tests
WO2011038403A1 (en)	2009-09-28	2011-03-31	Yuling Luo	Methods of detecting nucleic acid sequences with high specificity
WO2011044186A1 (en)	2009-10-06	2011-04-14	The Board Of Trustees Of The University Of Illinois	Human single-chain t cell receptors
CA2776756A1 (en)	2009-10-11	2011-04-14	Biogen Idec Ma Inc.	Anti-vla-4 related assays
AU2010315400B2 (en)	2009-10-27	2016-07-21	Caris Mpi, Inc.	Molecular profiling for personalized medicine
US8592151B2 (en) *	2009-11-17	2013-11-26	Musc Foundation For Research Development	Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
US9260517B2 (en)	2009-11-17	2016-02-16	Musc Foundation For Research Development	Human monoclonal antibodies to human nucleolin
GB0920089D0 (en)	2009-11-17	2009-12-30	Danisco	Method
US9910040B2 (en)	2012-07-09	2018-03-06	Sevident, Inc.	Molecular nets comprising capture agents and linking agents
US9733242B2 (en)	2012-10-07	2017-08-15	Sevident, Inc.	Devices for capturing analyte
CN102725308A (zh)	2009-11-30	2012-10-10	昆士兰技术大学	纤连蛋白:生长因子嵌合物
US9428586B2 (en)	2009-12-01	2016-08-30	Compugen Ltd	Heparanase splice variant
US8652788B2 (en)	2009-12-02	2014-02-18	Abbott Laboratories	Assay for diagnosis of cardiac myocyte damage
US8835120B2 (en) *	2009-12-02	2014-09-16	Abbott Laboratories	Assay for cardiac troponin-T (cTnT)
US8183002B2 (en) *	2009-12-03	2012-05-22	Abbott Laboratories	Autoantibody enhanced immunoassays and kits
US20110136141A1 (en)	2009-12-03	2011-06-09	Abbott Laboratories	Peptide reagents and method for inhibiting autoantibody antigen binding
EP2513308B1 (de)	2009-12-17	2017-01-18	Merck Sharp & Dohme Corp.	Modulation von pilr zur behandlung immunerkrankungen
GB0922377D0 (en)	2009-12-22	2010-02-03	Arab Gulf University The	Mutant LDL receptor
US11287423B2 (en)	2010-01-11	2022-03-29	Biogen Ma Inc.	Assay for JC virus antibodies
CA2784137A1 (en)	2010-01-11	2011-07-14	Biogen Idec Ma Inc.	Assay for jc virus antibodies
CA2784919A1 (en)	2010-01-26	2011-07-26	Banyan Biomarkers, Inc.	Compositions and methods relating to argininosuccinate synthetase
EP2528949A1 (de)	2010-01-27	2012-12-05	Yeda Research And Development Co. Ltd.	Antikörper zur hemmung von metalloproteinen
EP2529030B1 (de)	2010-01-29	2019-03-13	Advanced Cell Diagnostics, Inc.	Verfahren zum in situ nachweis von nukleinsäuren
JP5791634B2 (ja)	2010-01-29	2015-10-07	マイクロニクス，インコーポレイテッド	サンプル−回答型のマイクロ流体カートリッジ
US8574832B2 (en) *	2010-02-03	2013-11-05	Massachusetts Institute Of Technology	Methods for preparing sequencing libraries
TWI518325B (zh)	2010-02-04	2016-01-21	自治醫科大學	對ａｌｋ抑制劑具有先抗性或後抗性癌症的識別、判斷和治療
AU2011213609B2 (en)	2010-02-08	2016-11-03	Agensys, Inc.	Antibody drug conjugates (ADC) that bind to 161P2F10B proteins
WO2011106738A2 (en)	2010-02-25	2011-09-01	Fred Hutchinson Cancer Research Center	Use of tcr clonotypes as biomarkers for disease
EP2544688B1 (de)	2010-03-02	2016-09-07	President and Fellows of Harvard College	Verfahren und zusammensetzungen zur behandlung des angelman-syndroms
WO2011114251A1 (en)	2010-03-18	2011-09-22	Danisco A/S	Foodstuff
WO2011119484A1 (en)	2010-03-23	2011-09-29	Iogenetics, Llc	Bioinformatic processes for determination of peptide binding
US20150231215A1 (en)	2012-06-22	2015-08-20	Randolph J. Noelle	VISTA Antagonist and Methods of Use
US10745467B2 (en)	2010-03-26	2020-08-18	The Trustees Of Dartmouth College	VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
EP3153521B1 (de)	2010-03-26	2019-09-04	Trustees of Dartmouth College	Vista-regulatorisches t-zellen-mediator-protein, vista-bindende wirkstoffe und verwendung davon
US9125931B2 (en)	2010-04-06	2015-09-08	Massachusetts Institute Of Technology	Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers
CN103168118A (zh)	2010-04-06	2013-06-19	麻省理工学院	用减少数量的转录物测量进行的基因表达概况分析
PL2556090T3 (pl)	2010-04-09	2017-07-31	Critical Care Diagnostics, Inc.	Rozpuszczalne ludzkie przeciwciała st-2 i metody analityczne ich oznaczania
WO2011129382A1 (en)	2010-04-16	2011-10-20	Abbott Japan Co. Ltd.	Methods and reagents for diagnosing rheumatoid arthritis
WO2011133450A2 (en)	2010-04-19	2011-10-27	Meso Scale Technologies, Llc.	Serology assays
US10295472B2 (en)	2010-05-05	2019-05-21	Alverix, Inc.	Assay reader operable to scan a test strip
CA2798441A1 (en)	2010-05-07	2011-11-10	Abbvie Inc.	Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
US20120190563A1 (en)	2010-05-07	2012-07-26	Abbott Laboratories	Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
US9492508B2 (en)	2010-05-13	2016-11-15	The General Hospital Corporation	Parathyroid hormone analogs and uses thereof
US20110287458A1 (en)	2010-05-18	2011-11-24	The Texas A&M University System	Method and composition for the diagnosis and monitoring of inflammatory diseases
WO2011150186A1 (en)	2010-05-26	2011-12-01	The Board Of Trustees Of The University Of Illinois	Personal glucose meters for detection and quantification of a broad range of analytes
US8383580B2 (en)	2010-06-10	2013-02-26	The Regents Of The University Of Michigan	Methods of administering lipocalins to treat metabolic disorders and cardiovascular diseases
WO2011163401A2 (en)	2010-06-22	2011-12-29	Neogenix Oncology, Inc.	Colon and pancreas cancer specific antigens and antibodies
WO2012006056A2 (en)	2010-06-29	2012-01-12	Oregon Health & Science University	Ccr6 as a biomarker of alzheimer's disease
GB201011513D0 (en)	2010-07-08	2010-08-25	Danisco	Method
EP2407242A1 (de)	2010-07-13	2012-01-18	Dublin City University	Direkte Klonanalyse und Auswahltechnologie
WO2012009627A2 (en)	2010-07-16	2012-01-19	Vanderbilt University	Low resource processor using surface tension valves for extracting, concentrating and detecting molecular species
SG10201902596TA (en)	2010-07-16	2019-04-29	Bioatla Llc	Novel methods of protein evolution
BR112013001642A8 (pt)	2010-07-23	2016-10-11	Luminex Corp	coacoplamento para controlar a reatividade de reagentes em imunoensaios
US9120862B2 (en)	2010-07-26	2015-09-01	Abbott Laboratories	Antibodies relating to PIVKA-II and uses thereof
US9018434B2 (en)	2010-08-06	2015-04-28	Kimberly-Clark Worldwide, Inc.	Absorbent articles with intricate graphics
USD656852S1 (en)	2010-08-06	2012-04-03	Kimberly-Clark Worldwide, Inc.	Wetness indicator
US8956859B1 (en)	2010-08-13	2015-02-17	Aviex Technologies Llc	Compositions and methods for determining successful immunization by one or more vaccines
US8999335B2 (en)	2010-09-17	2015-04-07	Compugen Ltd.	Compositions and methods for treatment of drug resistant multiple myeloma
WO2012040168A2 (en)	2010-09-20	2012-03-29	Advanced Cell Diagnostics, Inc.	Biomarkers for differentiating melanoma from benign nevus in the skin
US9068014B2 (en)	2010-09-23	2015-06-30	Precision Biologics, Inc.	Colon and pancreas cancer peptidomimetics
WO2012040619A2 (en)	2010-09-24	2012-03-29	Massachusetts Eye And Ear Infirmary	Methods and compositions for prognosing and/or detecting age-related macular degeneration
TWI764324B (zh)	2010-09-29	2022-05-11	美商艾澤西公司	與191p4d12蛋白結合之抗體藥物共軛物(adc)
JP2013540127A (ja)	2010-10-04	2013-10-31	サントルナショナルドゥラルシェルシュシアンティフィク	表面ヌクレオリンの多価の人工リガンド及びグリコサミノグリカンを含む組成物
EP2441520A1 (de)	2010-10-12	2012-04-18	Eppendorf AG	Echtzeitverstärkungs- und Mikroarray-basierte Erkennung von Nukleinsäuretargets in einem Fluss-Chip-Assay
EP4300100A2 (de)	2010-10-14	2024-01-03	Meso Scale Technologies, LLC	Reagenzienlagerung in einer assay-vorrichtung
US8658361B2 (en)	2010-10-21	2014-02-25	Advanced Cell Diagnostics, Inc.	Ultra sensitive method for in situ detection of nucleic acids
AR084358A1 (es)	2010-12-27	2013-05-08	Lilly Co Eli	Composiciones y metodos para identificar y diferenciar componentes virales de vacunas multivalentes de la “fiebre de embarque” (complejo de enfermedad respiratoria bovina (brdc))
US9220640B2 (en)	2010-12-30	2015-12-29	Kimberly-Clark Worldwide, Inc.	Absorbent article including two dimensional code made from an active graphic
CA2822969C (en)	2010-12-31	2018-03-13	Jay M. Short	Comprehensive monoclonal antibody generation
WO2012099896A2 (en)	2011-01-17	2012-07-26	Life Technologies Corporation	Workflow for detection of ligands using nucleic acids
WO2012099576A1 (en)	2011-01-18	2012-07-26	Baxter International Inc.	Measurement of anti-amyloid antibodies in human blood
US8486717B2 (en)	2011-01-18	2013-07-16	Symbolics, Llc	Lateral flow assays using two dimensional features
EP2477032A1 (de)	2011-01-18	2012-07-18	Baxter International Inc	Messung von Antiamyloid-Antikörper in Menschenblut
ES2638640T3 (es)	2011-01-28	2017-10-23	Advanced Cell Diagnostics, Inc.	Ensayo de HPV RNAscope® para determinar el estado del HPV en los cánceres de cabeza y cuello y en lesiones cervicales
EP2673299B1 (de)	2011-02-07	2017-05-10	Research Development Foundation	Manipulierte immunglobulin-fc-polypeptide
US8603835B2 (en)	2011-02-10	2013-12-10	Chembio Diagnostic Systems, Inc.	Reduced step dual path immunoassay device and method
US9212258B2 (en)	2011-02-23	2015-12-15	The Board Of Trustees Of The University Of Illinois	Amphiphilic dendron-coils, micelles thereof and uses
CA2829300A1 (en)	2011-03-08	2012-09-13	King Abdullah University Of Science And Technology	Molecular biomarker set for early detection of ovarian cancer
WO2012125582A1 (en)	2011-03-11	2012-09-20	Board Of Regents Of The University Of Nebraska	Biomarker for coronary artery disease
EP2691538A1 (de)	2011-03-28	2014-02-05	Novartis AG	Marker im zusammenhang mit cyclinabhängigen kinasehemmern
MX340640B (es)	2011-04-01	2016-07-19	Immunogen Inc	Metodos para aumentar la eficacia de la terapia contra el cancer con receptor 1 de folato (folr1).
WO2012138941A1 (en)	2011-04-05	2012-10-11	Longevity Biotech, Inc.	Compositions comprising glucagon analogs and methods of making and using the same
MX2013011617A (es)	2011-04-08	2013-11-21	Danisco Us Inc	Composiciones.
US20120328567A1 (en)	2011-04-08	2012-12-27	Steven Bushnell	Biomarkers predictive of therapeutic responsiveness to ifnb and uses thereof
US9150644B2 (en)	2011-04-12	2015-10-06	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
WO2012140627A1 (en)	2011-04-15	2012-10-18	Compugen Ltd.	Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer
JP6457263B2 (ja)	2011-05-20	2019-01-23	オリゴメリックスインコーポレイテッド	タウプロテアーゼ組成物および使用方法
JP2014515476A (ja)	2011-05-20	2014-06-30	アボットジャパン株式会社	非特異的結合を減少させるためのイムノアッセイ方法及び試薬
CA2837184C (en)	2011-05-25	2021-09-21	Innate Pharma, S.A.	Anti-kir antibodies for the treatment of inflammatory and autoimmune disorders
PT2715352T (pt)	2011-05-31	2019-06-12	Biogen Ma Inc	Método de avaliação do risco de lmp
CA2839451A1 (en)	2011-06-27	2013-01-03	The Jackson Laboratory	Methods and compositions for treatment of cancer and autoimmune disease
EP2726503B1 (de)	2011-06-30	2019-09-04	Compugen Ltd.	Polypetide und ihre verwendung zur behandlung von autoimmunerkrankungen und infektionen
GB201112091D0 (en)	2011-07-14	2011-08-31	Gt Biolog Ltd	Bacterial strains isolated from pigs
WO2013010170A1 (en)	2011-07-14	2013-01-17	Lovell Mark A	Process for detection of alzheimer's disease from a serum sample
SG10201608671SA (en)	2011-07-18	2016-12-29	Harvard College	Engineered Microbe-Targeting Molecules and Uses Thereof
HUE039009T2 (hu)	2011-08-05	2018-12-28	Res Found Dev	Javított eljárások és készítmények Olfml3-mediált angiogenesis modulálására
CN103906535B (zh)	2011-08-15	2017-07-14	芝加哥大学	与葡萄球菌蛋白a的抗体相关的组合物和方法
CA2846197C (en)	2011-08-23	2024-01-16	Foundation Medicine, Inc.	Kif5b-ret fusion molecules and uses thereof
EP2771349B1 (de)	2011-09-16	2020-02-26	Iogenetics, LLC.	Bioinformatikverfahren zur bestimmung von peptidbindungen
WO2013043012A2 (en) *	2011-09-22	2013-03-28	Medicinal Bioconvergence Research Center	Novel use of leucyl trna synthetase
WO2013049455A1 (en)	2011-09-29	2013-04-04	William Blakely	Biodosimetry panels and methods
GB201117313D0 (en)	2011-10-07	2011-11-16	Gt Biolog Ltd	Bacterium for use in medicine
US20130164217A1 (en)	2011-12-21	2013-06-27	Meso Scale Technologies, Llc	Method of diagnosing, preventing and/or treating dementia & related disorders
CN104160039B (zh)	2011-12-29	2021-08-03	贝勒研究院	川崎病的生物标志物
KR102090934B1 (ko)	2012-01-09	2020-03-19	퍼킨엘머 헬스 사이언시즈, 아이엔씨.	마이크로유체 반응기 시스템
CA2862499C (en)	2012-01-24	2020-10-27	Cd Diagnostics, Inc.	System for detecting infection in synovial fluid
GB201201314D0 (en)	2012-01-26	2012-03-07	Isis Innovation	Composition
WO2013114367A2 (en)	2012-02-01	2013-08-08	Compugen Ltd.	C10rf32 antibodies, and uses thereof for treatment of cancer
WO2013116686A1 (en)	2012-02-02	2013-08-08	Massachusetts Institute Of Technology	Methods and products related to targeted cancer therapy
US9404923B2 (en)	2012-02-07	2016-08-02	Intuitive Biosciences, Inc.	Mycobacterium tuberculosis specific peptides for detection of infection or immunization in non-human primates
AU2013225938B2 (en)	2012-02-29	2017-08-10	Chemocentryx, Inc.	Pyrazol-1-yl benzene sulfonamides as CCR9 antagonists
CA2867902C (en)	2012-03-20	2023-09-26	Biogen Idec Ma Inc.	Jcv neutralizing antibodies
US10024860B2 (en)	2012-03-28	2018-07-17	Massachusetts Institute Of Technology	Cancer-related extracellular matrix signatures and related methods and products
WO2013148259A1 (en)	2012-03-28	2013-10-03	Massachusetts Institute Of Technology	Cancer-related extracellular matrix signatures and related methods and products
US20140178869A1 (en)	2012-04-05	2014-06-26	Advanced Cell Diagnostics, Inc.	Detection of immunoglobulin light chain restriction by rna in situ hybridization
US20130280696A1 (en)	2012-04-23	2013-10-24	Elliott Millenson	Devices and methods for detecting analyte in bodily fluid
NZ702282A (en)	2012-04-26	2016-07-29	Univ Chicago	Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease
MX362705B (es)	2012-05-10	2019-02-01	Bioatla Llc	Anticuerpos monoclonales multiespecíficos.
IN2014KN02831A (de)	2012-05-24	2015-05-08	Mountgate Group Ltd
US9492514B2 (en)	2012-06-01	2016-11-15	Icahn School Of Medicine At Mount Sinai	Ceramide levels in the treatment and prevention of infections
JP6366580B2 (ja)	2012-06-22	2018-08-01	エイチティージーモレキュラーダイアグノスティクス，インコーポレイテッド	メラニン細胞性病変における分子悪性度
WO2014039983A1 (en)	2012-09-07	2014-03-13	The Trustees Of Dartmouth College	Vista modulators for diagnosis and treatment of cancer
AU2013277051B2 (en)	2012-06-22	2018-06-07	King's College London	Novel VISTA-Ig constructs and the use of VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
US9890215B2 (en)	2012-06-22	2018-02-13	King's College London	Vista modulators for diagnosis and treatment of cancer
EP2870261B1 (de)	2012-07-09	2017-12-06	Novartis AG	Mit cdk-inhibitoren assoziierte biomarker
US9651549B2 (en)	2012-07-13	2017-05-16	Genisphere, Llc	Lateral flow assays using DNA dendrimers
US9874556B2 (en)	2012-07-18	2018-01-23	Symbolics, Llc	Lateral flow assays using two dimensional features
EP3327090A1 (de)	2012-07-18	2018-05-30	President and Fellows of Harvard College	Modifizierung von oberflächen zur gleichzeitigen abweisung und gezielten bindung gewünschter gruppen
CA2880098A1 (en)	2012-07-27	2014-01-30	The Board Of Trustees Of The University Of Illinois	Engineering t-cell receptors
CN104520714A (zh)	2012-07-31	2015-04-15	诺华股份有限公司	与对人双微体2(mdm2)抑制剂的敏感性相关的标志物
CA3163776A1 (en)	2012-08-03	2014-02-06	Foundation Medicine, Inc.	Human papilloma virus as predictor of cancer prognosis
EA201990839A1 (ru)	2012-08-23	2019-08-30	Эдженсис, Инк.	Конъюгаты антитело-лекарственное средство (adc), которые связываются с белками 158p1d7
WO2014043633A1 (en)	2012-09-17	2014-03-20	Agios Pharmaceuticals, Inc.	Use of e-cadherin and vimentin for selection of treatment responsive patients
CA2887933A1 (en)	2012-10-12	2014-04-17	Arizona Board Of Agents, On Behalf Of Arizona State University	Antibody based reagents that specifically recognize toxic oligomeric forms of tau
US20150354006A1 (en)	2012-10-19	2015-12-10	Novartis Ag	Markers for acute lymphoblastic leukemia
US10226744B2 (en)	2012-10-19	2019-03-12	Danisco Us Inc	Stabilization of biomimetic membranes
US9395369B2 (en)	2012-10-19	2016-07-19	Regents Of The University Of Minnesota	Guinea pig cytomegalovirus (CIDMTR strain)
US9803014B2 (en)	2012-10-24	2017-10-31	Research Development Foundation	JAM-C antibodies and methods for treatment of cancer
WO2014063205A1 (en)	2012-10-26	2014-05-01	The University Of Queensland	Use of endocytosis inhibitors and antibodies for cancer therapy
CA2890725A1 (en)	2012-11-05	2014-05-08	Pronai Therapeutics, Inc.	Methods of using biomarkers for the treatment of cancer by modulation of bcl2\|expression
CA2890207A1 (en)	2012-11-05	2014-05-08	Foundation Medicine, Inc.	Novel ntrk1 fusion molecules and uses thereof
WO2014087255A2 (en)	2012-11-21	2014-06-12	Oslo Universitetssykehus Hf	Systems and methods for monitoring biological fluids
US10011574B2 (en)	2012-11-21	2018-07-03	Agios Pharmaceuticals, Inc.	Glutaminase inhibitors and method of use
WO2014079011A1 (en)	2012-11-22	2014-05-30	Agios Pharmaceuticals, Inc.	Heterocyclic compounds for inhibiting glutaminase and their methods of use
CN104919035B (zh)	2012-12-21	2017-08-11	精密公司	便携式荧光检测系统和微测定盒
US10065186B2 (en)	2012-12-21	2018-09-04	Micronics, Inc.	Fluidic circuits and related manufacturing methods
EP2934751B1 (de)	2012-12-21	2019-05-29	Micronics, Inc.	Filme mit geringere elastizität zur mikrofluidischen verwendung
CA2896723C (en)	2012-12-28	2024-02-13	Precision Biologics, Inc.	Humanized monoclonal antibodies and methods of use for the diagnosis and treatment of colon and pancreas cancer
ES2761575T3 (es)	2013-01-02	2020-05-20	Qiagen Sciences Llc	Métodos para predecir el tiempo hasta el parto en una mujer embarazada
CA3107353A1 (en)	2013-01-04	2014-07-10	Meso Scale Technologies, Llc.	Assay apparatuses, methods and reagents
US10980804B2 (en)	2013-01-18	2021-04-20	Foundation Medicine, Inc.	Methods of treating cholangiocarcinoma
US10125373B2 (en)	2013-01-22	2018-11-13	Arizona Board Of Regents On Behalf Of Arizona State University	Geminiviral vector for expression of rituximab
US8968677B2 (en)	2013-01-22	2015-03-03	Quantum Design International, Inc.	Frazil ice conjugate assay device and method
WO2014121091A1 (en)	2013-02-01	2014-08-07	The Regents Of The University Of California	Methods for genome assembly and haplotype phasing
US9411930B2 (en)	2013-02-01	2016-08-09	The Regents Of The University Of California	Methods for genome assembly and haplotype phasing
JP6426110B2 (ja)	2013-02-01	2018-11-21	ザユナイテッドステイツオブアメリカ，アズリプレゼンテッドバイザセクレタリー，デパートメントオブヘルスアンドヒューマンサービシーズ	人口多能性幹細胞（ｉｐｓｃ）由来の網膜色素上皮（ｒｐｅ）細胞を生成するための方法
US20140309263A1 (en)	2013-02-01	2014-10-16	Meso Scale Technologies, Llc	Biomarkers of therapeutic responsiveness
US20140221368A1 (en)	2013-02-01	2014-08-07	Meso Scale Technologies, Llc	Biomarkers of therapeutic responsiveness
WO2014130846A1 (en)	2013-02-22	2014-08-28	Seungpyo Hong	Transdermal drug delivery using amphiphilic dendron-coil micelles
TWI582239B (zh)	2013-03-11	2017-05-11	諾華公司	與ｗｎｔ抑制劑相關之標記
US9273349B2 (en)	2013-03-14	2016-03-01	Affymetrix, Inc.	Detection of nucleic acids
WO2014159242A1 (en)	2013-03-14	2014-10-02	Novartis Ag	Notch 3 mutants and uses thereof
EP3611189A1 (de)	2013-03-14	2020-02-19	Novartis AG	Antikörper gegen notch 3
WO2014144666A2 (en)	2013-03-15	2014-09-18	The University Of Chicago	Methods and compositions related to t-cell activity
WO2014145718A2 (en)	2013-03-15	2014-09-18	Longevity Biotech, Inc.	Peptides comprising non-natural amino acids and methods of making and using the same
ES2756532T3 (es)	2013-03-15	2020-04-27	Gladiator Biosciences Inc	Dominios de Gla como agentes de direccionamiento
WO2014145797A2 (en)	2013-03-15	2014-09-18	Adair Charles	Method for treating eclampsia and preeclampsia
ES2751391T3 (es)	2013-03-21	2020-03-31	Univ Michigan Regents	Procedimientos de tratamiento de trastornos metabólicos
GB201306536D0 (en)	2013-04-10	2013-05-22	Gt Biolog Ltd	Polypeptide and immune modulation
WO2014172390A2 (en)	2013-04-15	2014-10-23	Cedars-Sinai Medical Center	Methods for detecting cancer metastasis
WO2014176306A1 (en)	2013-04-23	2014-10-30	Montecito Bio Sciences Ltd	Flow through testing system with pressure indicator
US20160091485A1 (en)	2013-04-25	2016-03-31	The Broad Institute, Inc.	Markers for ezh2 inhibitors
WO2014182661A2 (en)	2013-05-06	2014-11-13	Alnylam Pharmaceuticals, Inc	Dosages and methods for delivering lipid formulated nucleic acid molecules
WO2014182844A1 (en)	2013-05-07	2014-11-13	Micronics, Inc.	Microfluidic devices and methods for performing serum separation and blood cross-matching
WO2014182847A1 (en)	2013-05-07	2014-11-13	Micronics, Inc.	Device for preparation and analysis of nucleic acids
CA2911303C (en)	2013-05-07	2021-02-16	Micronics, Inc.	Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
GB201308658D0 (en)	2013-05-14	2013-06-26	Isis Innovation	Antibodies
CA2913155A1 (en)	2013-05-21	2014-11-27	President And Fellows Of Harvard College	Engineered heme-binding compositions and uses thereof
WO2014193804A1 (en)	2013-05-28	2014-12-04	Biogen Idec Ma Inc.	Method of assessing risk of pml
US9442051B2 (en) *	2013-06-10	2016-09-13	Yingjian Wang	Methods to accelerate the binding of biological molecules
WO2014200767A1 (en)	2013-06-12	2014-12-18	The General Hospital Corporation	Methods, kits, and systems for multiplexed detection of target molecules and uses thereof
RU2689553C2 (ru)	2013-06-18	2019-05-28	Днатрикс, Инк.	Лечение рака головного мозга онколитическим аденовирусом
EP3013362B1 (de)	2013-06-28	2021-08-04	Baylor Research Institute	Gegen dendritische zell-asgpr gerichtete immuntherapeutika für multiple sklerose
AU2014290044B2 (en)	2013-07-17	2020-10-29	Foundation Medicine, Inc.	Methods of treating urothelial carcinomas
SG11201600587VA (en)	2013-08-01	2016-02-26	Agensys Inc	Antibody drug conjugates (adc) that bind to cd37 proteins
US20150038365A1 (en)	2013-08-01	2015-02-05	Meso Scale Technologies, Llc	Lung cancer biomarkers
WO2015027120A1 (en)	2013-08-21	2015-02-26	Jiang Jean X	Compositions and methods for targeting connexin hemichannels
IL293871A (en)	2013-08-30	2022-08-01	Immunogen Inc	Antibodies and assays for the detection of folate receptor 1
CN108051590B (zh)	2013-09-13	2020-12-11	Symbolics有限责任公司	运用二维试验和对照信号读出模式的侧向层析检测
WO2015050959A1 (en)	2013-10-01	2015-04-09	Yale University	Anti-kit antibodies and methods of use thereof
EP3052193B1 (de)	2013-10-03	2018-01-31	Oklahoma Medical Research Foundation	Biomarker für die krankheitsaktivität, die intensität und das auftreten von systemischem lupus erythematodes
US9476884B2 (en)	2013-10-04	2016-10-25	University Of Massachusetts	Hybridization- independent labeling of repetitive DNA sequence in human chromosomes
WO2015063604A2 (en)	2013-11-01	2015-05-07	Imberti Luisa	BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO IFNβ AND USES THEREOF
US20170002064A1 (en)	2013-11-08	2017-01-05	The Board Of Regents Of The University Of Texas System	Vh4 antibodies against gray matter neuron and astrocyte
WO2015073707A1 (en)	2013-11-15	2015-05-21	The Board Of Trustees Of The Leland Stanford Junior University	Methods of treating heart failure with agonists of hypocretin receptor 2
EP3071240B1 (de)	2013-11-20	2021-01-06	University of Iowa Research Foundation	Verfahren zur überwachung der wirksamkeit der behandlung von alzheimer mit einer apoe isoform
MX371202B (es)	2013-11-22	2020-01-22	Univ Illinois	Receptores de células t humanas con alta afinidad modificados por medio de manipulación genética.
EP3074039A4 (de)	2013-11-26	2017-10-11	The Brigham and Women's Hospital, Inc.	Zusammensetzungen und verfahren zur modulierung einer immunreaktion
US10513546B2 (en)	2013-12-18	2019-12-24	President And Fellows Of Harvard College	CRP capture/detection of gram positive bacteria
DK3083936T3 (en)	2013-12-19	2018-10-22	Danisco Us Inc	USE OF HYDROPHOBINES TO INCREASE GAS TRANSFER IN AEROBE FERMENTATION PROCESSES
US11014987B2 (en)	2013-12-24	2021-05-25	Janssen Pharmaceutics Nv	Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
CN106661107B (zh)	2013-12-24	2021-12-24	杨森制药公司	抗vista抗体及片段
DK3447493T3 (da)	2014-01-07	2020-08-17	Bioatla Llc	Proteinrettede ortologer
CA2936833A1 (en)	2014-01-13	2015-07-16	Baylor Research Institute	Novel vaccines against hpv and hpv-related diseases
CN106132992B (zh)	2014-01-29	2020-08-07	达娜-法勃肿瘤研究所公司	针对muc1-c/胞外结构域(muc1-c/ecd)的抗体
US20150247204A1 (en)	2014-02-07	2015-09-03	The General Hopital Corporation	Differential diagnosis of hepatic neoplasms
US20150232935A1 (en)	2014-02-14	2015-08-20	The General Hospital Corporation	Methods for diagnosing igg4-related disease
ES2818823T3 (es)	2014-02-27	2021-04-14	Biogen Ma Inc	Método de evaluación del riesgo de LMP
WO2015131099A1 (en)	2014-02-28	2015-09-03	The General Hospital Corporation	Diagnosis of multiple myeloma and lymphoma
KR20160127149A (ko)	2014-03-21	2016-11-02	아지오스 파마슈티컬스 아이엔씨.	화합물 및 이의 사용 방법
EP3126486B1 (de)	2014-04-02	2019-07-03	Chembio Diagnostic Systems, Inc.	Immunoassay mit fangkonjugat
CA2983796A1 (en)	2014-04-25	2015-10-29	The Brigham And Women's Hospital, Inc.	Compositions and methods for treating subjects with immune-mediated diseases
EP2942627A1 (de)	2014-05-05	2015-11-11	MicroBPlex, Inc.	MIT VON NEULICH PROLIFERIERTEN ANTIKöRPER SEKRETIERENDEN ZELLEN NEU SYNTHETISIERTEN ANTIKÖRPERN (MENSA) ELABORIERTE MEDIEN UND VERWENDUNGEN DAVON
WO2015171938A1 (en)	2014-05-08	2015-11-12	Novodiax, Inc.	Direct immunohistochemistry assay
WO2015172083A1 (en)	2014-05-08	2015-11-12	Biogen Ma Inc.	Dimethylfumarate and prodrugs for treatment of multiple sclerosis
EP3143399A1 (de)	2014-05-12	2017-03-22	Biogen MA Inc.	Biomarker zur vorhersage des fortschreitens von lupus und verwendungen davon
US9568404B2 (en)	2014-05-16	2017-02-14	Junyu Mai	Method and apparatus for biomolecule analysis
WO2015179435A1 (en)	2014-05-19	2015-11-26	Bayer Healthcare Llc	Optimized humanized monoclonal antibodies against activated protein c and uses thereof
JP6997619B2 (ja)	2014-06-11	2022-01-17	キャシー・エイ・グリーン	液性免疫の抑制または増進のための、ｖｉｓｔａアゴニスト及びｖｉｓｔａアンタゴニストの使用
GB201413240D0 (en)	2014-07-25	2014-09-10	Hansa Medical Ab	Method
CA2956925C (en)	2014-08-01	2024-02-13	Dovetail Genomics, Llc	Tagging nucleic acids for sequence assembly
WO2016026978A1 (en)	2014-08-22	2016-02-25	Universite Nice Sophia Antipolis	Methods and pharmaceutical compositions for treating drug addiction
US20180010132A1 (en)	2014-09-11	2018-01-11	Novartis Ag	Inhibition of prmt5 to treat mtap-deficiency-related diseases
PL3110447T3 (pl)	2014-09-16	2020-10-19	Synermore Biologics Co., Ltd.	Przeciwciało anty-EGFR i jego zastosowania
AU2015328396B2 (en)	2014-10-06	2021-02-04	Chemocentryx, Inc.	Combination therapy of inhibitors of C-C chemokine receptor type 9 (CCR9) and anti-alha4beta7 integrin blocking antibodies
US10774388B2 (en)	2014-10-08	2020-09-15	Novartis Ag	Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
US20170253921A1 (en)	2014-10-13	2017-09-07	Life Technologies Corporation	Methods, kits & compositions for determining gene copy numbers
DK3209773T3 (da)	2014-10-24	2020-06-15	Dupont Nutrition Biosci Aps	Prolintolerante tripeptidylpeptidaser og anvendelser deraf
EP3172329A1 (de)	2014-10-24	2017-05-31	Danisco US Inc.	Verfahren zur herstellung von alkoholen durch verwendung einer tripeptidylpeptidase
US20160116466A1 (en)	2014-10-27	2016-04-28	Chembio Diagnostic Systems, Inc.	Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses
US11279974B2 (en)	2014-12-01	2022-03-22	The Broad Institute, Inc.	Method for in situ determination of nucleic acid proximity
WO2016089883A1 (en)	2014-12-01	2016-06-09	Novartis Ag	Compositions and methods for diagnosis and treatment of prostate cancer
AU2015357463B2 (en)	2014-12-05	2021-10-07	Immunext, Inc.	Identification of VSIG8 as the putative vista receptor and its use thereof to produce vista/VSIG8 modulators
US10539566B2 (en)	2014-12-08	2020-01-21	Berg Llc	Use of markers including filamin A in the diagnosis and treatment of prostate cancer
PT3065748T (pt)	2014-12-23	2018-02-28	4D Pharma Res Ltd	Uma estirpe de bacteroides thetaiotaomicron e o seu uso na redução da inflamação
MX2017008449A (es)	2014-12-23	2017-10-12	4D Pharma Res Ltd	Polipeptido de pirina y modulacion inmune.
AU2016219511B2 (en)	2015-02-09	2020-11-12	Research Development Foundation	Engineered immunoglobulin Fc polypeptides displaying improved complement activation
GB201502305D0 (en)	2015-02-12	2015-04-01	Hansa Medical Ab	Protein
GB201502306D0 (en)	2015-02-12	2015-04-01	Hansa Medical Ab	Protein
SG11201706730XA (en)	2015-02-17	2017-09-28	Dovetail Genomics Llc	Nucleic acid sequence assembly
WO2016138312A2 (en)	2015-02-25	2016-09-01	Vanderbilt University	Antibody-mediated neutralization of marburg virus
EP3268038B1 (de)	2015-03-09	2021-05-05	Agensys, Inc.	An flt3-proteine bindende antikörper-wirkstoffkonjugate (adc)
EP3268462B1 (de)	2015-03-11	2021-08-11	The Broad Institute, Inc.	Genotyp- und phänotypkupplung
WO2016154540A1 (en)	2015-03-26	2016-09-29	Dovetail Genomics Llc	Physical linkage preservation in dna storage
US9612534B2 (en)	2015-03-31	2017-04-04	Tokyo Electron Limited	Exposure dose homogenization through rotation, translation, and variable processing conditions
US11279768B1 (en)	2015-04-03	2022-03-22	Precision Biologics, Inc.	Anti-cancer antibodies, combination therapies, and uses thereof
US9927443B2 (en)	2015-04-10	2018-03-27	Conquerab Inc.	Risk assessment for therapeutic drugs
EP3286216B1 (de)	2015-04-23	2022-06-08	Nevada Research & Innovation Corporation	Pilznachweis mit mannan-epitop
EP3091026B1 (de)	2015-05-08	2019-02-20	Centrillion Technology Holdings Corporation	Disulfidvernetzte reversible terminatoren
SI3240554T1 (sl)	2015-06-15	2019-12-31	4D Pharma Research Limited,	Blautia stercosis in wexlerae za uporabo v zdravljenju vnetnih in avtoimunskih bolezni
MA41010B1 (fr)	2015-06-15	2020-01-31	4D Pharma Res Ltd	Compositions comprenant des souches bactériennes
MA41060B1 (fr)	2015-06-15	2019-11-29	4D Pharma Res Ltd	Compositions comprenant des souches bactériennes
LT3360559T (lt)	2015-06-15	2019-12-27	4D Pharma Research Limited	Kompozicijos, apimančios bakterijų kamienus
TWI733676B (zh)	2015-06-15	2021-07-21	英商4D製藥研究有限公司	包含細菌菌株之組合物
CN107922497B (zh)	2015-06-24	2022-04-12	詹森药业有限公司	抗vista抗体和片段
US11473073B2 (en)	2015-06-26	2022-10-18	Dupont Nutrition Biosciences Aps	Aminopeptidases for protein hydrolyzates
WO2017011329A1 (en)	2015-07-10	2017-01-19	West Virginia University	Markers of stroke and stroke severity
US10877045B2 (en)	2015-07-21	2020-12-29	Saint Louis University	Compositions and methods for diagnosing and treating endometriosis-related infertility
AU2016301231A1 (en)	2015-08-04	2018-02-22	Cd Diagnostics, Inc.	Methods for detecting adverse local tissue reaction (ALTR) necrosis
DK3332255T3 (da)	2015-08-06	2020-09-07	Lia Diagnostics Inc	Vanddispergerbare analyser
EP3331549B1 (de)	2015-08-06	2020-12-23	President and Fellows of Harvard College	Verbesserte mikrobenbindende moleküle und verwendungen davon
EP3337908A4 (de)	2015-08-18	2019-01-23	The Broad Institute, Inc.	Verfahren und zusammensetzungen zur veränderung der funktion und struktur von chromatinschleifen und/oder -domänen
US10852309B2 (en)	2015-08-25	2020-12-01	Prothena Biosciences Limited	Methods for detecting phosphorylated alpha-synuclein
WO2017040380A2 (en)	2015-08-28	2017-03-09	Research Development Foundation	Engineered antibody fc variants
EP3344756A4 (de)	2015-09-02	2019-09-04	University of Massachusetts	Nachweis von genloci mit crispr-arrayed-repeats und/oder polychromatischen single-guide-ribonukleinsäuren
WO2017040930A2 (en)	2015-09-03	2017-03-09	The Trustees Of The University Of Pennsylvania	Biomarkers predictive of cytokine release syndrome
CA3036409C (en)	2015-09-08	2023-07-11	Erik J. Sontheimer	Dnase h activity of neisseria meningitidis cas9
WO2017053567A1 (en)	2015-09-22	2017-03-30	Delta Tm Technologies	Designing customized protein-specific buffer systems
CA3000405A1 (en)	2015-09-29	2017-04-06	Htg Molecular Diagnostics, Inc.	Methods for subtyping diffuse large b-cell lymphoma (dlbcl)
US20190062394A1 (en)	2015-10-10	2019-02-28	Intrexon Corporation	Improved Therapeutic Control of Proteolytically Sensitive, Destabilized Forms of Interleukin-12
DK3362462T3 (da)	2015-10-12	2021-10-11	Advanced Cell Diagnostics Inc	In situ-detektion af nukleotidvarianter i prøver med højt støjniveau, og sammensætninger og fremgangsmåder relateret dertil
CN108368542B (zh)	2015-10-19	2022-04-08	多弗泰尔基因组学有限责任公司	用于基因组组装、单元型定相以及独立于靶标的核酸检测的方法
US9377457B1 (en)	2015-10-19	2016-06-28	Naishu Wang	Progressive compression driven flow cartridge for analyte detecting strip and method
WO2017077392A1 (en)	2015-11-06	2017-05-11	Oslo Universitetssykehus Hf	Methods and devices for detecting methanol poisoning using formate oxidase
WO2017083296A1 (en)	2015-11-09	2017-05-18	The Children's Hospital Of Philadelphia	Glypican 2 as a cancer marker and therapeutic target
GB201520497D0 (en)	2015-11-20	2016-01-06	4D Pharma Res Ltd	Compositions comprising bacterial strains
BR112018010089A2 (pt)	2015-11-20	2018-11-13	4D Pharma Res Ltd	composições compreendendo cepas bacterianas
GB201520638D0 (en)	2015-11-23	2016-01-06	4D Pharma Res Ltd	Compositions comprising bacterial strains
GB201520631D0 (en)	2015-11-23	2016-01-06	4D Pharma Res Ltd	Compositions comprising bacterial strains
JP7090545B2 (ja)	2015-12-02	2022-06-24	ストキューブアンドシーオー．，インコーポレイテッド	Ｂｔｎ１ａ１に免疫特異的に結合する抗体及び分子並びにそれらの治療的使用
WO2017096017A1 (en)	2015-12-02	2017-06-08	Stsciences, Inc.	Antibodies specific to glycosylated btla (b- and t- lymphocyte attenuator)
SG11201804648RA (en)	2015-12-04	2018-06-28	Univ Texas	Slc45a2 peptides for immunotherapy
EP3387154A4 (de)	2015-12-09	2019-05-15	Intuitive Biosciences, Inc.	Automatisiertes silberveredelungssystem
JOP20200228A1 (ar)	2015-12-21	2017-06-16	Novartis Ag	تركيبات وطرق لخفض تعبير البروتين tau
US10920224B2 (en)	2015-12-22	2021-02-16	The Regents Of The University Of Colorado, A Body Corporate	Protecting RNAs from degradation using engineered viral RNAs
WO2017139419A1 (en)	2016-02-11	2017-08-17	Qiagen Waltham, Inc.	Polyphenolic additives in sequencing-by-synthesis
US10036011B2 (en)	2016-02-11	2018-07-31	Qiagen Waltham, Inc.	Scavenger compounds for improved sequencing-by-synthesis
EP3413910A1 (de)	2016-02-12	2018-12-19	Janssen Pharmaceutica NV	Anti-vista (b7h5)-antikörper
WO2017147186A1 (en)	2016-02-22	2017-08-31	Ursure, Inc.	System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
SG11201807117WA (en)	2016-02-23	2018-09-27	Dovetail Genomics Llc	Generation of phased read-sets for genome assembly and haplotype phasing
BR112018015589A2 (pt)	2016-02-25	2019-10-01	Dupont Nutrition Biosci Aps	método para produzir hidrolisado de proteína que emprega uma tripeptidil peptidase de aspergillus fumigatus
AU2017224122B2 (en)	2016-02-26	2024-04-11	The Board Of Regents Of The University Of Texas System	Connexin (Cx) 43 hemichannel-binding antibodies and uses thereof
CA3015913A1 (en)	2016-02-29	2017-09-08	Foundation Medicine, Inc.	Methods of treating cancer
GB201612191D0 (en)	2016-07-13	2016-08-24	4D Pharma Plc	Compositions comprising bacterial strains
SG11201807195VA (en)	2016-03-04	2018-09-27	4D Pharma Plc	Compositions comprising bacterial blautia strains for treating visceral hypersensitivity
WO2017165438A1 (en)	2016-03-25	2017-09-28	Muralidhar Reddy Moola	Combinatorial synthesis and biomarker development
CN109195991B (zh)	2016-03-29	2023-10-31	斯特库比股份有限公司	对糖基化pd-l1特异的双重功能抗体及其使用方法
EP3436480A4 (de)	2016-03-30	2019-11-27	Musc Foundation for Research Development	Verfahren zur behandlung und diagnose von krebs durch targeting von glycoprotein a repetitions predominant (garp) und zur effektiven immuntherapie allein oder in kombination
US9903866B2 (en)	2016-04-05	2018-02-27	Conquerab Inc.	Portable devices for detection of antibodies against therapeutic drugs
ES2866880T3 (es)	2016-04-13	2021-10-20	Inst Nat Sante Rech Med	Métodos y kits para la detección rápida del clon O25B-ST131 de Escherichia Coli
US9702872B1 (en)	2016-04-15	2017-07-11	Dnt Scientific Research, Llc	Rapid diagnostic test device by driven flow technology
US9632083B1 (en)	2016-04-15	2017-04-25	Dnt Scientific Research, Llc	Rapid diagnostic test device by driven flow technology
UA125382C2 (uk)	2016-04-15	2022-03-02	Імьюнекст Інк.	Антитіла проти людського vista та їх застосування
WO2017194589A1 (en)	2016-05-10	2017-11-16	Vib Vzw	Inhibition of tau-mediated early synaptic dysfunction
JP2019522487A (ja)	2016-05-13	2019-08-15	ダブテイルゲノミクスエルエルシー	保存されたサンプルからの長距離連鎖情報の回復
CN109476764A (zh)	2016-05-16	2019-03-15	哈佛大学校长及研究员协会	偶联在经co2-等离子体活化的表面上的水性生物分子
WO2017214068A1 (en)	2016-06-05	2017-12-14	Berg Llc	Systems and methods for patient stratification and identification of potential biomarkers
AU2017277065A1 (en)	2016-06-06	2019-01-17	Medizinische Universität Wien	Method for the detection of an IgM antibody specific for a flavivirus in a sample
US9535061B1 (en)	2016-06-29	2017-01-03	Dnt Scientific Research, Llc	Multi-functional rapid diagnostic test device
EP3482202A4 (de)	2016-07-11	2020-03-18	Arizona Board of Regents on behalf of Arizona State University	Schweiss als biofluid zur analyse und krankheitserkennung
TWI802545B (zh)	2016-07-13	2023-05-21	英商４Ｄ製藥有限公司	包含細菌菌株之組合物
WO2018015296A1 (en)	2016-07-20	2018-01-25	Vib Vzw	Therapeutic agents for neurological and psychiatric disorders
US11746152B2 (en)	2016-07-20	2023-09-05	Stcube, Inc.	Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated PD-L1
WO2018045162A1 (en)	2016-09-01	2018-03-08	Biogen Ma Inc.	Biomarkers predictive of primary progressive multiple sclerosis and uses thereof
US20180128828A1 (en)	2016-11-04	2018-05-10	James W. Stave	Direct detection of microorganisms in patient samples by immunoassay
US11162129B2 (en)	2016-11-09	2021-11-02	IsoPlexis Corporation	Photoprotective mixtures as imaging reagents in sequencing-by-synthesis
IL266751B (en)	2016-11-23	2022-07-01	Chemocentryx Inc	A method for the treatment of focal segmental tuberous sclerosis
CN110199031A (zh)	2016-11-29	2019-09-03	基因组影像公司	设计用于分析感兴趣的遗传区域中的特定事件的一组多核苷酸序列的方法
GB201621123D0 (en)	2016-12-12	2017-01-25	4D Pharma Plc	Compositions comprising bacterial strains
EP3555625A1 (de)	2016-12-16	2019-10-23	Merck Patent GmbH	Verfahren zur verwendung von im urin nachgewiesenen galectin-3-bindenden protein zur überwachung des schweregrades und der progression von lupus nephritis
US10656164B2 (en)	2016-12-22	2020-05-19	Qiagen Sciences, Llc	Screening asymptomatic pregnant woman for preterm birth
US10935555B2 (en)	2016-12-22	2021-03-02	Qiagen Sciences, Llc	Determining candidate for induction of labor
CN110462062A (zh)	2017-01-26	2019-11-15	俄克拉荷马医学研究基金会	系统性红斑狼疮疾病活动性、强度和急性发作的生物标志物
KR102607101B1 (ko)	2017-01-26	2023-11-29	제트엘아이피 홀딩 리미티드	Cd47 항원 결합 유닛 및 그것의 사용
WO2018163051A1 (en)	2017-03-06	2018-09-13	Novartis Ag	Methods of treatment of cancer with reduced ubb expression
WO2018203145A1 (en)	2017-05-03	2018-11-08	Oslo Universitetssykehus Hf	Systems and methods for monitoring biological fluids
PT3630136T (pt)	2017-05-22	2021-06-11	4D Pharma Res Ltd	Composições que compreendem estirpes bacterianas
MA41708A (fr)	2017-05-24	2020-04-08	4D Pharma Res Ltd	Compositions comprenant des souches bactériennes
CN111051346A (zh)	2017-05-31	2020-04-21	斯特库伯株式会社	使用免疫特异性结合btn1a1的抗体和分子治疗癌症的方法
KR20200015602A (ko)	2017-05-31	2020-02-12	주식회사 에스티큐브앤컴퍼니	Btn1a1에 면역특이적으로 결합하는 항체 및 분자 및 이의 치료적 용도
WO2018226671A1 (en)	2017-06-06	2018-12-13	Stcube & Co., Inc.	Methods of treating cancer using antibodies and molecules that bind to btn1a1 or btn1a1-ligands
LT3638271T (lt)	2017-06-14	2021-01-11	4D Pharma Research Limited	Kompozicijos, apimančios bakterines padermes
RS60910B1 (sr)	2017-06-14	2020-11-30	4D Pharma Res Ltd	Kompozicije koje sadrže bakterijski soj roda megasphaera i njihove upotrebe
US9784733B1 (en)	2017-06-22	2017-10-10	Dnt Scientific Research, Llc	Rapid diagnostic test device by driven flow technology
EP4220171A3 (de)	2017-07-21	2023-10-25	Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca	Marker für endometriumkrebs
EP4085919A3 (de)	2017-07-21	2023-02-08	Novartis AG	Zusammensetzungen und verfahren zur behandlung von krebs
US9823244B1 (en)	2017-07-31	2017-11-21	Dnt Scientific Research, Llc	Digital progressive compression driven flow cartridge for analyte detecting device and method
EP3672990A1 (de)	2017-08-25	2020-07-01	Five Prime Therapeutics, Inc.	B7-h4-antikörper und verfahren zur verwendung davon
EP3626745A4 (de)	2017-09-01	2021-03-17	Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.	Rekombinanter bispezifischer antikörper
BR112020004319A2 (pt)	2017-09-05	2020-09-08	GLAdiator Biosciences, Inc.	método de alvejamento de exossomas
US11464784B2 (en)	2017-09-15	2022-10-11	The Regents Of The University Of California	Inhibition of aminocylase 3 (AA3) in the treatment of cancer
EP3692152A4 (de)	2017-10-04	2021-12-01	The Broad Institute, Inc.	Verfahren und zusammensetzungen zur veränderung der funktion und struktur von chromatinschleifen und/oder -domänen
AU2018347361A1 (en)	2017-10-11	2020-04-30	Chemocentryx, Inc.	Treatment of focal segmental glomerulosclerosis with CCR2 antagonists
US11525002B2 (en)	2017-10-11	2022-12-13	Board Of Regents, The University Of Texas System	Human PD-L1 antibodies and methods of use therefor
CA3082365A1 (en)	2017-11-09	2019-05-16	Pinteon Therapeutics Inc.	Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies
CN109870581B (zh)	2017-12-04	2021-05-04	厦门万泰凯瑞生物技术有限公司	一种定量检测HBsAg的试剂盒及方法
CA3085324A1 (en)	2017-12-15	2019-06-20	Syngenta Participations Ag	Non-antibody ligands for detecting target proteins
EP3735589A2 (de)	2018-01-05	2020-11-11	Vanderbilt University	Antikörpervermittelte neutralisierung des chikungunya-virus
WO2019155041A1 (en)	2018-02-12	2019-08-15	Vib Vzw	Gβγ COMPLEX ANTIBODIES AND USES THEREOF
US20200408771A1 (en)	2018-02-22	2020-12-31	The United States Of America,As Represented By The Secretary,Department Of Health And Human Services	Cd153 and/or cd30 in infection
SG11202008105RA (en)	2018-03-02	2020-09-29	Five Prime Therapeutics Inc	B7-h4 antibodies and methods of use thereof
WO2019173703A1 (en)	2018-03-08	2019-09-12	Meso Scale Technologies, Llc.	Genetic marker and/or biomarkers for traumatic brain injury, and ultrasensitive assays for biomarkers of traumatic brain injury
WO2019182896A1 (en)	2018-03-23	2019-09-26	Board Of Regents, The University Of Texas System	Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor
EP4063519B1 (de)	2018-04-09	2023-09-13	Advanced Cell Diagnostics, Inc.	Verfahren zur weiteren erhöhung der signalverstärkung für den in-situ-nachweis von nukleinsäuren
CA3098096A1 (en)	2018-04-24	2019-10-31	Ampsource Biopharma Shanghai Inc.	Antibody against tim-3 and application thereof
EP3788138A1 (de)	2018-05-02	2021-03-10	Novartis AG	Regulatoren von menschlichen pluripotenten stammzellen und verwendungen davon
WO2019237119A1 (en)	2018-06-08	2019-12-12	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	New compositions and detection methods for onchocerca volvulus infection
WO2019244107A1 (en)	2018-06-21	2019-12-26	Daiichi Sankyo Company, Limited	Compositions including cd3 antigen binding fragments and uses thereof
WO2020014353A1 (en)	2018-07-11	2020-01-16	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Monoclonal antibody for the detection of the antiretroviral drug emtricitabine (ftc, 2',3'-dideoxy-5-fluoro-3'-thiacytidine)
CA3107352A1 (en)	2018-07-23	2020-01-30	Enclear Therapies, Inc.	Methods of treating neurological disorders
CN113164563A (zh)	2018-07-23	2021-07-23	因柯利尔疗法公司	神经性病症的治疗方法
TW202019480A (zh)	2018-09-13	2020-06-01	美國德州系統大學評議委員會	新穎lilrb4抗體及其用途
AU2019342197A1 (en)	2018-09-21	2021-04-15	President And Fellows Of Harvard College	Methods and compositions for treating diabetes, and methods for enriching mRNA coding for secreted proteins
EP3856753A4 (de)	2018-09-28	2022-11-16	Centrillion Technology Holdings Corporation	Disulfidvernetzte reversible terminatoren
EA202191033A1 (ru)	2018-10-15	2021-12-21	Юниверсити Оф Массачусетс	Программируемое редактирование оснований днк посредством слитых белков nme2cas9-дезаминаза
KR102554477B1 (ko)	2018-10-18	2023-07-11	오클라호마 메디컬 리써치 화운데이션	질병 활성도의 특징을 규명하는 전신 홍반성 낭창(sle) 질병 활성도 면역 지수를 위한 생체지표
BR112021007690A2 (pt)	2018-10-22	2021-08-10	Shanghai GenBase Biotechnology Co., Ltd.	anticorpo anti-cldn18.2 e uso do mesmo
CA3115887A1 (en)	2018-10-23	2020-04-30	Glycardial Diagnostics, S.L.	Antibodies specific for glycosylated apoj and uses thereof
US10451613B1 (en)	2018-11-09	2019-10-22	Dnt Scientific Research, Llc	Rapid diagnostic test device and sampling method using driven flow technology
CN111196851B (zh)	2018-11-20	2021-11-16	厦门万泰凯瑞生物技术有限公司	针对人抗缪勒管激素的特异性抗体及其应用
JP2022513437A (ja)	2018-11-28	2022-02-08	オレゴンヘルスアンドサイエンスユニバーシティー	治療用第ｘｉｉ因子抗体
MX2021006234A (es)	2018-11-30	2021-09-10	Caris Mpi Inc	Perfilado molecular de proxima generacion.
EP3904386A4 (de)	2018-12-28	2022-09-07	Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.	Antikörper und verwendung davon
JP2022518489A (ja)	2019-01-25	2022-03-15	プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ	核酸を合成するための組成物および方法
US11300576B2 (en)	2019-01-29	2022-04-12	Arizona Board Of Regents On Behalf Of Arizona State University	DARPin reagents that distinguish Alzheimer's disease and Parkinson's disease samples
US20220154262A1 (en)	2019-02-15	2022-05-19	Advanced Cell Diagnostics, Inc.	Methods for multiplex detection of nucleic acids by in situ hybridization
EP3952947A1 (de)	2019-04-11	2022-02-16	Enclear Therapies, Inc.	Verfahren zur verbesserung von liquor sowie vorrichtungen und systeme dafür
WO2020211674A1 (zh)	2019-04-16	2020-10-22	四川科伦博泰生物医药股份有限公司	抗FXI/FXIa抗体及其用途
US20200377951A1 (en)	2019-04-30	2020-12-03	Chondrial Therapeutics, Inc.	Frataxin-sensitive markers for determining effectiveness of frataxin replacement therapy
US11549943B2 (en)	2019-05-31	2023-01-10	International Business Machines Corporation	Multiplexed lateral flow assay device
US11906515B2 (en) *	2019-05-31	2024-02-20	International Business Machines Corporation	Multiplexed lateral flow assay device
EP3980182A1 (de)	2019-06-04	2022-04-13	Abbott Toxicology Limited	Analyse von flüssigkeitsproben
DE102019117413A1 (de) *	2019-06-27	2020-12-31	Testo SE & Co. KGaA	Fließtest-Einheit, Set und Verwendung einer Fließtest-Einheit zur Durchführung einer Nachweisreaktion
DE102019117289A1 (de)	2019-06-27	2020-12-31	Katja Werner	Trägermaterial, Kitsystem und Verfahren für biologische Assays
US20220257653A1 (en)	2019-07-19	2022-08-18	The Children's Hospital Of Philadelphia	Chimeric antigen receptors containing glypican 2 binding domains
CA3145278A1 (en)	2019-07-26	2021-02-04	Vanderbilt University	Human monoclonal antibodies to enterovirus d68
JP2023501871A (ja)	2019-09-20	2023-01-20	上海吉倍生物技術有限公司	Ｂｃｍａ標的化抗体及びキメラ抗原受容体
US20220411511A1 (en)	2019-09-26	2022-12-29	Stcube & Co.	Antibodies specific to glycosylated ctla-4 and methods of use thereof
EP4039704A4 (de)	2019-09-30	2023-09-20	Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.	Anti-pd-1-antikörper und verwendung davon
WO2021072277A1 (en)	2019-10-09	2021-04-15	Stcube & Co.	Antibodies specific to glycosylated lag3 and methods of use thereof
CA3160211A1 (en)	2019-11-05	2021-05-14	Meso Scale Technologies, Llc.	Methods and kits for quantitating radiation exposure
US10792360B1 (en)	2019-11-21	2020-10-06	Chemocentryx, Inc.	Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
US20230021837A1 (en)	2019-11-26	2023-01-26	Meso Scale Technologies, Llc.	Methods and kits for detecting autoimmune diseases
WO2021112918A1 (en)	2019-12-02	2021-06-10	Caris Mpi, Inc.	Pan-cancer platinum response predictor
AU2020400056A1 (en)	2019-12-12	2022-07-07	President And Fellows Of Harvard College	Compositions and methods for light-directed biomolecular barcoding
MX2022004919A (es)	2019-12-13	2022-05-16	Sichuan Kelun Biotech Biopharmaceutical Co Ltd	Anticuerpo anti-linfopoyetina estromal timica (tslp) y sus usos.
KR20220143005A (ko)	2019-12-20	2022-10-24	노바록 바이오테라퓨틱스 리미티드	항-인터루킨-23 p19 항체 및 이의 사용 방법
EP3842452A1 (de)	2019-12-26	2021-06-30	Universitat Autònoma de Barcelona	Gerüstproteine und therapeutische nanokonjugate auf nidogenbasis
CN113061165A (zh)	2020-01-02	2021-07-02	厦门大学	EB病毒BNLF2b基因编码多肽及其检测用途
WO2021156490A2 (en)	2020-02-06	2021-08-12	Vib Vzw	Corona virus binders
US20210277092A1 (en)	2020-02-11	2021-09-09	Vanderbilt University	HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2)
WO2021167908A1 (en)	2020-02-17	2021-08-26	Board Of Regents, The University Of Texas System	Methods for expansion of tumor infiltrating lymphocytes and use thereof
US20230087785A1 (en)	2020-02-25	2023-03-23	Vib Vzw	Leucine-Rich Repeat Kinase 2 Allosteric Modulators
US11345741B2 (en)	2020-03-26	2022-05-31	Vanderbilt University	Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
WO2021195385A1 (en)	2020-03-26	2021-09-30	Vanderbilt University	HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-GoV-2)
TW202203916A (zh)	2020-03-31	2022-02-01	美商卡默森屈有限公司	使用ｃｃｒ９抑制劑及抗ｉｌ—２３阻斷抗體治療發炎性腸道疾病的組成物及方法
AU2021261343A1 (en)	2020-04-22	2022-11-03	President And Fellows Of Harvard College	Isothermal methods, compositions, kits, and systems for detecting nucleic acids
US20230184768A1 (en)	2020-05-01	2023-06-15	Meso Scale Technologies, Llc.	Viral serology ace2 competition assays
IL298184A (en)	2020-05-15	2023-01-01	Sichuan Kelun Biotech Biopharmaceutical Co Ltd	Antibody conjugates with a drug, a method for their preparation and their use
EP3939999A1 (de)	2020-07-14	2022-01-19	Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO)	Antikörper zur neutralisierung der interleukin-11-rezeptor-alpha-unterheinheit (il11ra) und verwendungen davon
WO2022047359A1 (en)	2020-08-31	2022-03-03	Berg Llc	Protein biomarkers for pancreatic cancer
CA3193584A1 (en)	2020-09-04	2022-03-10	Novarock Biotherapeutics, Ltd.	Nectin-4 antibodies and uses thereof
GB202105804D0 (en)	2020-11-20	2021-06-09	Univ Cape Town	Use of microvirin in the identification of mycobacterium tuberculosis mannose-capped lipoarabinomannan
CN117460543A (zh)	2020-12-04	2024-01-26	田纳西大学研究基金会	用于诊断淀粉样蛋白病的方法
TW202227502A (zh)	2020-12-31	2022-07-16	大陸商和鉑醫藥（蘇州）有限公司	人lifr抗原結合蛋白及其製備方法和應用
GB2603166A (en)	2021-01-29	2022-08-03	Thelper As	Therapeutic and Diagnostic Agents and Uses Thereof
KR20230145038A (ko)	2021-02-09	2023-10-17	메디링크 테라퓨틱스 (쑤저우) 컴퍼니, 리미티드	생물활성 물질 접합체, 이의 제조방법 및 이의 용도
WO2022175532A1 (en)	2021-02-19	2022-08-25	Vib Vzw	Cation-independent mannose-6-phosphate receptor binders
JP2024512337A (ja)	2021-03-05	2024-03-19	シャンハイ、ケンパーソー、バイオテクノロジー、カンパニー、リミテッド	抗ｃｌｄｎ６抗体およびその使用
EP4304660A1 (de)	2021-03-08	2024-01-17	ImmunoGen, Inc.	Verfahren zur erhöhung der wirksamkeit von auf adam9 abzielenden immunkonjugaten zur behandlung von krebs
CA3207635A1 (en)	2021-03-09	2022-09-15	Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.	Ror1 binding protein and use thereof
IL307530A (en)	2021-04-06	2023-12-01	Bpgbio Inc	Estrogen receptor-like (ER) breast cancer protein markers LUMINAL A (LA) and LUMINAL B1 (LB1)
WO2022216846A1 (en)	2021-04-06	2022-10-13	Berg Llc	Protein markers for estrogen receptor (er)-positive-like and estrogen receptor (er)-negative-like breast cancer
IL307528A (en)	2021-04-06	2023-12-01	Bpgbio Inc	Protein markers for the prognosis of breast cancer progression
EP4327103A1 (de)	2021-04-19	2024-02-28	Temple Therapeutics BV	Verfahren zum nachweis oder zur behandlung von endometrium- und ovarialhyperproliferativen erkrankungen
EP4341692A1 (de)	2021-05-21	2024-03-27	Meso Scale Technologies, LLC	Serologische tests für virenstämme
WO2023288046A1 (en)	2021-07-15	2023-01-19	President And Fellows Of Harvard College	Compositions and methods relating to cells with adhered particles
CA3224607A1 (en)	2021-07-23	2023-01-26	Fundacio Hospital Universitari Vall D'hebron - Institut De Recerca	Biomarkers for endometrial cancer
WO2023016828A2 (en)	2021-07-30	2023-02-16	Vib Vzw	Cation-independent mannose-6-phosphate receptor binders for targeted protein degradation
WO2023081070A1 (en)	2021-11-02	2023-05-11	University Of Massachusetts	Nme2Cas9 INLAID DOMAIN FUSION PROTEINS
WO2023089377A2 (en)	2021-11-19	2023-05-25	Mirobio Limited	Engineered pd-1 antibodies and uses thereof
GB202201137D0 (en)	2022-01-28	2022-03-16	Thelper As	Therapeutic and diagnostic agents and uses thereof
EP4238988A1 (de)	2022-03-01	2023-09-06	Consejo Superior De Investigaciones Científicas	Antikörper gegen sars-cov-2 und verwendungen davon
WO2023192976A1 (en)	2022-04-01	2023-10-05	Board Of Regents, The University Of Texas System	Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor
GB202204813D0 (en)	2022-04-01	2022-05-18	Bradcode Ltd	Human monoclonal antibodies and methods of use thereof
WO2023196866A1 (en)	2022-04-06	2023-10-12	Mirobio Limited	Engineered cd200r antibodies and uses thereof
US20230357851A1 (en)	2022-04-06	2023-11-09	Larimar Therapeutics, Inc.	Frataxin-sensitive markers for monitoring frataxin-replacement therapy
WO2023239710A1 (en)	2022-06-08	2023-12-14	Onkure, Inc.	Benzopyrimidin-4(3h)-ones as pi3k inhibitors
WO2023240201A1 (en)	2022-06-08	2023-12-14	Larimar Therapeutics, Inc.	Frataxin-sensitive markers for monitoring progression and treatment of leigh syndrome
US20240010742A1 (en)	2022-06-10	2024-01-11	Research Development Foundation	Engineered fcriib selective igg1 fc variants and uses thereof
WO2023245184A1 (en)	2022-06-17	2023-12-21	Meso Scale Technologies, Llc.	Viral strain serology assays
WO2024028794A1 (en)	2022-08-02	2024-02-08	Temple Therapeutics BV	Methods for treating endometrial and ovarian hyperproliferative disorders
WO2024040020A1 (en)	2022-08-15	2024-02-22	Absci Corporation	Quantitative affinity activity specific cell enrichment
WO2024038160A1 (en)	2022-08-18	2024-02-22	Vib Vzw	Means and methods to modulate neuron excitability
WO2024054469A1 (en)	2022-09-08	2024-03-14	Onkure, Inc.	Isoquinolones as pi3k inhibitors
WO2024064024A1 (en)	2022-09-19	2024-03-28	Onkure, Inc.	((4-oxo-3,4-dihydroquinazolin-8-yl)methyl)amine derivatives as p13k inhibitors for the treatment of cancer
WO2024064002A1 (en)	2022-09-20	2024-03-28	Onkure, Inc.	Hdac inhibitor oki-179 for the treatment of cancers resulting from a mapk pathway mutation
US20240103002A1 (en)	2022-09-23	2024-03-28	Meso Scale Technologies, Llc.	Orthopoxvirus serology assays
WO2024068744A1 (en)	2022-09-27	2024-04-04	Vib Vzw	Antivirals against human parainfluenza virus

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3811840A (en) *	1969-04-01	1974-05-21	Miles Lab	Test device for detecting low concentrations of substances in fluids
US4190496A (en) *	1971-05-14	1980-02-26	Syva Company	Homogeneous enzyme assay for antibodies
IT1006557B (it) *	1971-09-08	1976-10-20	Bagshawe Kenneth Dawson	Cella di reazione particolarmente utile in prove di radioimmunita
JPS4939720A (de) *	1972-08-26	1974-04-13
DE2436598C2 (de) *	1974-07-30	1983-04-07	Boehringer Mannheim Gmbh, 6800 Mannheim	Stabiler Teststreifen zum Nachweis von Inhaltsstoffen in Flüssigkeiten
SE388694B (sv) *	1975-01-27	1976-10-11	Kabi Ab	Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
US4094647A (en) *	1976-07-02	1978-06-13	Thyroid Diagnostics, Inc.	Test device
CA1095819A (en) *	1977-01-14	1981-02-17	Eastman Kodak Company	Element for analysis of liquids
IL51354A (en) *	1977-01-28	1979-07-25	Ames Yissum Ltd	Assay method for the quantitative determination of a hapten in aqueous solution
US4160008A (en) *	1978-01-26	1979-07-03	Miles Laboratories, Inc.	Multilayered test device for determining the presence of a liquid sample component, and method of use
US4226978A (en) *	1978-03-13	1980-10-07	Miles Laboratories, Inc.	β-Galactosyl-umbelliferone-labeled aminoglycoside antibiotics and intermediates in their preparation
US4233402A (en) *	1978-04-05	1980-11-11	Syva Company	Reagents and method employing channeling
AU531777B2 (en) *	1978-04-05	1983-09-08	Syva Co.	Label/solid conjugate immunoassay system
US4258001A (en) *	1978-12-27	1981-03-24	Eastman Kodak Company	Element, structure and method for the analysis or transport of liquids
US4301139A (en) *	1979-06-21	1981-11-17	Ames-Yissum Ltd.	Multilayer column chromatography specific binding assay method, test device and test kit
US4299916A (en) *	1979-12-26	1981-11-10	Syva Company	Preferential signal production on a surface in immunoassays

1980
- 1980-08-07 US US06/176,177 patent/US4366241A/en not_active Expired - Lifetime
1981
- 1981-06-23 EP EP81302826A patent/EP0046004B1/de not_active Expired
- 1981-06-23 AT AT81302826T patent/ATE10548T1/de not_active IP Right Cessation
- 1981-06-23 DE DE8181302826T patent/DE3167436D1/de not_active Expired
- 1981-08-05 CA CA000383264A patent/CA1174595A/en not_active Expired
- 1981-08-07 JP JP56123946A patent/JPS5763454A/ja active Granted
1986
- 1986-11-07 SG SG891/86A patent/SG89186G/en unknown
1987
- 1987-02-19 HK HK158/87A patent/HK15887A/xx not_active IP Right Cessation
- 1987-12-30 MY MY300/87A patent/MY8700300A/xx unknown
1990
- 1990-05-25 JP JP2134266A patent/JPH0654317B2/ja not_active Expired - Lifetime
1994
- 1994-02-14 JP JP6017069A patent/JP2505979B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0046004A1 (de)	1982-02-17
US4366241A (en)	1982-12-28
JPH06317596A (ja)	1994-11-15
JP2505979B2 (ja)	1996-06-12
JPS5763454A (en)	1982-04-16
JPH0654317B2 (ja)	1994-07-20
CA1174595A (en)	1984-09-18
JPH0322589B2 (de)	1991-03-27
SG89186G (en)	1987-03-27
JPH03142361A (ja)	1991-06-18
MY8700300A (en)	1987-12-31
HK15887A (en)	1987-02-27
ATE10548T1 (de)	1984-12-15
EP0046004B1 (de)	1984-11-28
US4366241B1 (de)	1988-10-18

Legal Events

Date	Code	Title	Description
1999-08-19	8327	Change in the person/name/address of the patent owner	Owner name: DADE BEHRING MARBURG GMBH, 35041 MARBURG, DE

Publication	Publication Date	Title
US4366241B1 (de)	1988-10-18
ES8202364A1 (es)	1982-01-16	Un metodo para detectar la presencia de un material analiza-ble en una muestra
GR3003073T3 (en)	1993-02-17	Solid phase assay employing capillary flow
DE2963773D1 (en)	1982-11-11	Immunological determination process
SE7904386L (sv)	1979-11-20	Biologisk provmetod med utnyttjande av fast fas
DE3172347D1 (en)	1985-10-24	Method for producing an analytical antibody probe, an analytical antibody probe, and a method for analysing a sample for certain antibodies
JPS5324015A (en)	1978-03-06	Method and apparatus for detection of antigen-antibody reaction
IL77890A (en)	1991-06-10	Method for determining an analyte that is a specific binding pair(spb)member by using a test strip carrying a second sbp and kit therefor
AU2790989A (en)	1989-05-02	Method to produce immunodiagnostic reagents
ATE74662T1 (de)	1992-04-15	Immunoanalysetestverfahren fuer cholesterolepoxide.
KR850002385A (ko)	1985-05-13	PIVKA-Ⅱ의 측정(assay)용 방법 및 시약
EP0230934A3 (de)	1989-09-06	Monoklonaler Antikörper, Verfahren zur Messung eines glucosylierten Proteins unter Verwendung von diesem monoklonalen Antikörper, und Kit dafür
BE857121A (fr)	1977-11-14	Antigene et anticorps pour un essai de determination immunologique de la thymopoietine, et leur application
EP0088974A3 (de)	1986-05-28	Homogenes immunologisches Verfahren mit markiertem, monoclonalem Antianalyten
MY103022A (en)	1993-04-30	Monoclonal antibodies recognizing l-thyroxine
DE3273844D1 (en)	1986-11-20	Procedure for immunological determinations using two antibodies, the second antibody being purified by affinity chromatography, and supports therefor
HU905685D0 (en)	1991-03-28	Process for detecting analytes
JPS6415657A (en)	1989-01-19	Solid phase antibody for immunoassay
JPS5386014A (en)	1978-07-29	Quantitative analysis of antigen and antibody
FR2441847A1 (fr)	1980-06-13	Procede pour la detection quantitative et qualitative des antigenes, anticorps et haptenes
JPS5347517A (en)	1978-04-28	Immobilized antibody membrane for antigen protein determinationmethod and its apparatus
JPS6486066A (en)	1989-03-30	Reagent for immunological analysis
EP0387777A3 (de)	1992-01-02	Verfahren zum Nachweis von FGF und zur Diagnose von Tumoren
ES8608321A1 (es)	1986-06-16	Hibridomas productores de anticuerpos monoclonales especifi-cos para la inmunoglobulina e (ige)humana del mieloma ns
SE8603312L (sv)	1988-02-06	Sett att overvaka fermentering