DE3168891D1 - 9-amino-1-hydroxyoctahydrobenzo(c)quinolines and derivatives thereof - Google Patents

9-amino-1-hydroxyoctahydrobenzo(c)quinolines and derivatives thereof

Info

Publication number
DE3168891D1
DE3168891D1 DE8181303339T DE3168891T DE3168891D1 DE 3168891 D1 DE3168891 D1 DE 3168891D1 DE 8181303339 T DE8181303339 T DE 8181303339T DE 3168891 T DE3168891 T DE 3168891T DE 3168891 D1 DE3168891 D1 DE 3168891D1
Authority
DE
Germany
Prior art keywords
hydroxyoctahydrobenzo
quinolines
derivatives
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181303339T
Other languages
English (en)
Inventor
Michael Ross Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE3168891D1 publication Critical patent/DE3168891D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines
DE8181303339T 1980-07-28 1981-07-21 9-amino-1-hydroxyoctahydrobenzo(c)quinolines and derivatives thereof Expired DE3168891D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/173,207 US4309545A (en) 1980-07-28 1980-07-28 Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof

Publications (1)

Publication Number Publication Date
DE3168891D1 true DE3168891D1 (en) 1985-03-28

Family

ID=22630983

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181303339T Expired DE3168891D1 (en) 1980-07-28 1981-07-21 9-amino-1-hydroxyoctahydrobenzo(c)quinolines and derivatives thereof

Country Status (29)

Country Link
US (1) US4309545A (de)
EP (1) EP0045171B1 (de)
JP (1) JPS57112372A (de)
KR (1) KR850000273B1 (de)
AR (1) AR230988A1 (de)
AT (1) ATE11775T1 (de)
AU (1) AU525944B2 (de)
CA (1) CA1178274A (de)
CS (1) CS228515B2 (de)
DD (1) DD202012A5 (de)
DE (1) DE3168891D1 (de)
DK (1) DK334581A (de)
EG (1) EG15535A (de)
ES (1) ES8301926A1 (de)
FI (1) FI812338L (de)
GR (1) GR75283B (de)
GT (1) GT198170557A (de)
HU (1) HU185133B (de)
IE (1) IE51426B1 (de)
IL (1) IL63423A0 (de)
IN (1) IN158867B (de)
NO (2) NO812557L (de)
NZ (1) NZ197856A (de)
PH (1) PH17281A (de)
PL (1) PL133928B1 (de)
PT (1) PT73440B (de)
SU (1) SU1217254A3 (de)
YU (1) YU185181A (de)
ZA (1) ZA815128B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4920221A (en) * 1982-03-16 1990-04-24 Pfizer Inc. Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US5605906A (en) * 1995-03-24 1997-02-25 Merck Frosst Canada, Inc. Cannabinoid receptor agonists
CA2245142C (en) * 1996-01-31 2004-11-30 Byk Gulden Lomberg Chemische Fabrik Gmbh New phenanthridines
US6127378A (en) * 1996-03-26 2000-10-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phenanthridines substituted in the 6 position
ATE224386T1 (de) * 1996-03-26 2002-10-15 Altana Pharma Ag Neue in 6-position substituierte phenanthridine
US5776482A (en) * 1996-03-29 1998-07-07 University Of Iowa Research Foundation Tetrahydroquinoline analogues for use in glaucoma treatment
ES2184318T3 (es) * 1997-07-25 2003-04-01 Altana Pharma Ag 6-alquilfenantridinas sustituidas.
PT1000035E (pt) * 1997-07-25 2003-04-30 Altana Pharma Ag 6-fenilfenantridinas substituidas
EP1189603A2 (de) 1999-03-22 2002-03-27 Immugen Pharmaceuticals, Inc. Behandlung von immunerkrankungen wie hiv-erkrankung und neoplastischen erkrankungen
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US20060084021A1 (en) * 2004-09-10 2006-04-20 Kubicek Chris A Wick holder
WO2002026728A2 (en) * 2000-09-28 2002-04-04 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
US20020137802A1 (en) * 2000-09-28 2002-09-26 Travis Craig R. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
AU2003214226A1 (en) * 2002-03-18 2003-10-08 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
BRPI0511462A (pt) * 2004-05-25 2007-12-26 Othera Pharmaceuticals Inc medicamentos e pró-medicamentos óculo-seletivos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839441A (en) * 1969-10-27 1974-10-01 Hoffmann La Roche Intermediates for partially hydrogenated phenanthridines
US3878219A (en) * 1973-07-13 1975-04-15 Abbott Lab 5H-{8 1{9 benzopyrano{8 3,4-d{9 pyridines
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
HU180917B (hu) 1976-05-17 1983-05-30 Pfizer Eljárás 5, 6, 6a, 7-tetrahidro-benzo [c] kinolin-9(8H)-on-származékok előállítására
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
US4152450A (en) * 1978-02-17 1979-05-01 Eli Lilly And Company 9-Amino-dibenzopyrans

Also Published As

Publication number Publication date
PT73440B (en) 1983-06-20
NO854454L (no) 1985-01-29
PL232331A1 (en) 1983-09-26
SU1217254A3 (ru) 1986-03-07
YU185181A (en) 1983-12-31
EP0045171A3 (en) 1982-04-28
ES504323A0 (es) 1982-12-16
ZA815128B (en) 1982-07-28
AR230988A1 (es) 1984-08-31
CS228515B2 (en) 1984-05-14
DK334581A (da) 1982-01-29
KR830006217A (ko) 1983-09-20
JPS57112372A (en) 1982-07-13
PH17281A (en) 1984-07-06
FI812338L (fi) 1982-01-29
KR850000273B1 (ko) 1985-03-15
GT198170557A (es) 1983-01-12
EP0045171B1 (de) 1985-02-13
ATE11775T1 (de) 1985-02-15
NO812557L (no) 1982-01-29
PL133928B1 (en) 1985-07-31
GR75283B (de) 1984-07-13
US4309545A (en) 1982-01-05
HU185133B (en) 1984-12-28
AU525944B2 (en) 1982-12-09
IL63423A0 (en) 1981-10-30
AU7343481A (en) 1982-05-06
IE811686L (en) 1982-01-28
IN158867B (de) 1987-02-07
ES8301926A1 (es) 1982-12-16
EP0045171A2 (de) 1982-02-03
IE51426B1 (en) 1986-12-24
PT73440A (en) 1981-08-01
DD202012A5 (de) 1983-08-24
NZ197856A (en) 1984-10-19
CA1178274A (en) 1984-11-20
EG15535A (en) 1986-09-30

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Free format text: LEDERER, F., DIPL.-CHEM. DR., PAT.-ANW., 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee