DE330433T1 - Geschuetzte chemilumineszierende markierungen. - Google Patents

Geschuetzte chemilumineszierende markierungen.

Info

Publication number
DE330433T1
DE330433T1 DE198989301679T DE89301679T DE330433T1 DE 330433 T1 DE330433 T1 DE 330433T1 DE 198989301679 T DE198989301679 T DE 198989301679T DE 89301679 T DE89301679 T DE 89301679T DE 330433 T1 DE330433 T1 DE 330433T1
Authority
DE
Germany
Prior art keywords
label
protected
linked
specific binding
binding partner
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE198989301679T
Other languages
English (en)
Inventor
Lyle John San Diego California 92117 Us Arnold
Alexander Atkinson San Diego California 92123 Us Waldrop Iii
Philip W. San Diego California 92116 Us Hammond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gen Probe Inc
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Publication of DE330433T1 publication Critical patent/DE330433T1/de
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
DE198989301679T 1988-02-26 1989-02-22 Geschuetzte chemilumineszierende markierungen. Pending DE330433T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/160,611 US4950613A (en) 1988-02-26 1988-02-26 Proteted chemiluminescent labels

Publications (1)

Publication Number Publication Date
DE330433T1 true DE330433T1 (de) 1990-05-03

Family

ID=22577607

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198989301679T Pending DE330433T1 (de) 1988-02-26 1989-02-22 Geschuetzte chemilumineszierende markierungen.
DE68926259T Expired - Fee Related DE68926259T2 (de) 1988-02-26 1989-02-22 Geschützte chemilumineszierende Markierungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE68926259T Expired - Fee Related DE68926259T2 (de) 1988-02-26 1989-02-22 Geschützte chemilumineszierende Markierungen

Country Status (15)

Country Link
US (1) US4950613A (de)
EP (1) EP0330433B1 (de)
JP (1) JPH02503268A (de)
KR (1) KR0132290B1 (de)
AT (1) ATE137021T1 (de)
AU (1) AU626319B2 (de)
CA (1) CA1333396C (de)
DE (2) DE330433T1 (de)
DK (1) DK530489A (de)
ES (1) ES2012323T3 (de)
FI (1) FI895062A0 (de)
GR (1) GR900300054T1 (de)
NO (1) NO894218L (de)
PT (1) PT89834B (de)
WO (1) WO1989008256A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6414152B1 (en) * 1981-12-11 2002-07-02 University Of Wales College Of Medicine Of Heath Park Luminescent labelling material and procedures
US5605795A (en) * 1986-07-24 1997-02-25 Tropix, Inc. Assays using chemiluminescent, enzymatically cleavable substituted 1,2-dioxetanes and kits therefor
US5110932A (en) * 1986-10-06 1992-05-05 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US5284951A (en) * 1987-12-31 1994-02-08 London Diagnostics, Inc. Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom
US5338847A (en) * 1987-12-31 1994-08-16 London Diagnostics, Inc. Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom by adduct formation
US5321136A (en) * 1987-12-31 1994-06-14 London Diagnostics, Inc. Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom
US5227489A (en) * 1988-08-01 1993-07-13 Ciba Corning Diagnostics Corp. Stable hydrophilic acridinium esters suitable for liposome encapsulation
US5663074A (en) * 1988-09-26 1997-09-02 Chiron Diagnostics Corporation Nucleophilic polysubstituted aryl acridinium ester conjugates and syntheses thereof
US5241070A (en) * 1988-09-26 1993-08-31 Ciba Corning Diagnostics Corp. Nucleophilic polysubstituted aryl acridinium esters and uses thereof
US5629168A (en) * 1992-02-10 1997-05-13 British Technology Group Limited Chemiluminescent enhancers
AU3936393A (en) * 1992-03-27 1993-11-08 Abbott Laboratories Haptens, tracers, immunogens and antibodies for acridine-9-carboxylic acids
US6002000A (en) * 1992-07-20 1999-12-14 Dade Behring Marburg Gmbh Chemiluminescent compounds and methods of use
EP0651752A1 (de) * 1992-07-20 1995-05-10 Behringwerke Ag Chemilumineszierende derivate und methoden deren anwendung
JP3584379B2 (ja) * 1993-02-04 2004-11-04 持田製薬株式会社 アクリジニウム化合物およびアクリジニウム化合物複合体
US5670644A (en) * 1993-05-17 1997-09-23 Lumigen, Inc. Acridan compounds
JPH08233820A (ja) * 1995-02-23 1996-09-13 Kdk Corp 化学発光測定法
US5731148A (en) * 1995-06-07 1998-03-24 Gen-Probe Incorporated Adduct protection assay
JP3338061B2 (ja) * 1996-07-16 2002-10-28 オランダ国 ジベンゾジヒドロピリジンカルボン酸エステル類及びそれらの化学ルミネセント分析法への利用
WO1998054578A1 (en) * 1997-05-29 1998-12-03 Bio-Rad Laboratories, Inc. Chemiluminescent hemoglobin assay
AU2012232986B2 (en) * 1998-05-01 2014-06-12 Gen-Probe Incorporated System and method for incubating the contents of a reaction receptacle
DE10011529T1 (de) 1998-05-01 2011-09-01 Gen-Probe Incorporated Automatisches Diagnoseanalysegerät und Verfahren
US6238927B1 (en) 1998-10-05 2001-05-29 Mosaic Technologies, Incorporated Reverse displacement assay for detection of nucleic acid sequences
US6673560B1 (en) * 1998-11-25 2004-01-06 Bayer Corporation Measurement of hydride using chemiluminescent acridinium compounds and applications thereof
WO2000047777A1 (en) 1999-02-12 2000-08-17 Gen-Probe Incorporated Protection probes
US6127140A (en) * 1999-06-18 2000-10-03 Abbott Laboratories Assay for quantitative measurement of analytes in biological samples
US6723851B2 (en) * 2001-10-31 2004-04-20 Quest Diagnostics Investment Incorporated Chemiluminescent compounds and use thereof
CN1653338A (zh) 2002-05-17 2005-08-10 贝克顿·迪金森公司 用于分离、放大和检测目标核酸序列的自动化系统
EP1618215A4 (de) * 2003-05-01 2007-12-05 Gen Probe Inc Oligonukleotide als molekularer schalter
CN101128603A (zh) * 2005-02-28 2008-02-20 卫材R&D管理有限公司 信号扩增方法
US8008066B2 (en) 2005-03-10 2011-08-30 Gen-Probe Incorporated System for performing multi-formatted assays
EP1921454B1 (de) 2005-03-10 2015-08-12 Gen-Probe Incorporated Systeme und Verfahren zur Durchführung von Tests zum Nachweis oder zur Quantifizierung von Analyten
EP2749887A3 (de) 2010-07-23 2014-10-01 Beckman Coulter, Inc. System oder Verfahren zur Aufnahme analytischer Einheiten
EP2776843B1 (de) 2011-11-07 2019-03-27 Beckman Coulter, Inc. Zentrifugensystem und arbeitsablauf
JP6062449B2 (ja) 2011-11-07 2017-01-18 ベックマン コールター， インコーポレイテッド 標本コンテナ検出
KR20140091032A (ko) 2011-11-07 2014-07-18 베크만 컬터, 인코포레이티드 검체 수송 시스템의 자기 감쇠
EP2776848B1 (de) 2011-11-07 2019-12-25 Beckman Coulter, Inc. System und verfahren zum transport von probenbehältern
CN104040352B (zh) 2011-11-07 2016-09-07 贝克曼考尔特公司 机械臂
EP3373015A1 (de) 2011-11-07 2018-09-12 Beckman Coulter Inc. Aliquotierungssystem und arbeitsablauf
US10427162B2 (en) 2016-12-21 2019-10-01 Quandx Inc. Systems and methods for molecular diagnostics

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6771981A (en) * 1979-12-19 1981-07-22 Electro-Nucleonics Inc. Chemical luminescence amplification substrate system for immuno chemistry
US4372745A (en) * 1979-12-19 1983-02-08 Electro-Nucleonics, Inc. Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer
EP0082636B2 (de) * 1981-12-11 2006-10-18 The Welsh National School of Medicine Lumineszierende Markierungssubstanzen und -verfahren
DE3645292C2 (de) * 1986-08-22 1997-12-11 Hoechst Ag Chemilumineszenzimmunoassays und ein Verfahren zu ihrer Herstellung
US4745181A (en) * 1986-10-06 1988-05-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US4927769A (en) * 1987-07-08 1990-05-22 Ciba Corning Diagnostics Corp. Method for enhancement of chemiluminescence
ES2074051T3 (es) * 1987-09-21 1995-09-01 Gen Probe Inc Ensayo de proteccion homogeneo.
NZ227506A (en) * 1987-12-31 1992-06-25 London Diagnostics Inc Specific binding assays using chemiluminescent compounds

Also Published As

Publication number Publication date
EP0330433A3 (de) 1991-02-27
DK530489D0 (da) 1989-10-25
NO894218D0 (no) 1989-10-24
DE68926259D1 (de) 1996-05-23
CA1333396C (en) 1994-12-06
DE68926259T2 (de) 1996-09-19
ES2012323T3 (es) 1996-06-16
GR900300054T1 (en) 1991-07-31
KR0132290B1 (ko) 1998-04-11
ATE137021T1 (de) 1996-05-15
EP0330433B1 (de) 1996-04-17
PT89834A (pt) 1989-10-04
AU626319B2 (en) 1992-07-30
AU4072389A (en) 1989-09-22
WO1989008256A1 (en) 1989-09-08
JPH02503268A (ja) 1990-10-11
PT89834B (pt) 1994-02-28
EP0330433A2 (de) 1989-08-30
NO894218L (no) 1989-12-22
KR900700885A (ko) 1990-08-17
FI895062A0 (fi) 1989-10-25
US4950613A (en) 1990-08-21
ES2012323A4 (es) 1990-03-16
DK530489A (da) 1989-12-27

Similar Documents

Publication Publication Date Title
ATE137021T1 (de) Geschützte chemilumineszierende markierungen
ES2000910A6 (es) Procedimiento para preparar piridina-2,3-dicarboxilatos sustituidos y disustituidos
CO5140073A1 (es) Derivados de 2,3,4,5-tetrahidro-1h-3-benzapina
ATE177743T1 (de) Langkettiger carbonsäureimidester
NO983970L (no) Tricykliske forbindelser, deres fremstilling og anvendelse
DE69001187T2 (de) 6-epifumagillole, ihre herstellung und ihre verwendung.
DK37888A (da) Cannabinolderivat
EP1219626A4 (de) Verbdindungen zur floureszenz-kennzeichnung
ATE342896T1 (de) Fluoreszierende proben zur quantitativen bestimmung von zink
FI93353B (fi) Menetelmä ACAT-inhiboivien kinoliinijohdannaisten valmistamiseksi
KR880002823A (ko) 약제학적 화합물
KR860007209A (ko) 트리치환 안식향산 중간체의 제법
KR840003628A (ko) 피리딜화합물의 제조방법
AU5197599A (en) Fluorescent labelling reagents
KR880005138A (ko) 신규 화합물들
NO902017L (no) Organisk kjemisk forbindelse, flytende krystallmateriale inneholdende denne og flytende krystallinnretning inneholdende dette.
DE69105098T2 (de) Radioaktive Jodverbindung zur Markierung von Antikörpern.
KR850002977A (ko) 아졸릴-테트라하이드로푸란-2-일이덴-메탄 유도체의 제조방법
KR850006394A (ko) 치환된 옥시란의 제조방법
Zhong et al. New procedure for the preparation of 2, 3-dihydro-1, 5-benzothiazepin-4 (5 H)-ones promoted by samarium diiodide
IT1180645B (it) Intermedi per la sintesi di acidi carbossilici
KR870007898A (ko) 벤조[h]신놀린 화합물의 제조방법
ATE101160T1 (de) Herstellung von 2,3'-anhydro-2'deoxyuridinderivaten.
FR2664597B1 (fr) Procede de preparation de sulfonylpristinamycine iib.
AR021563A1 (es) Proceso de preparacion de derivados de piridazi-3-non