DE3469132D1 - Process for the fractionation of blood plasma - Google Patents

Process for the fractionation of blood plasma

Info

Publication number
DE3469132D1
DE3469132D1 DE8484400602T DE3469132T DE3469132D1 DE 3469132 D1 DE3469132 D1 DE 3469132D1 DE 8484400602 T DE8484400602 T DE 8484400602T DE 3469132 T DE3469132 T DE 3469132T DE 3469132 D1 DE3469132 D1 DE 3469132D1
Authority
DE
Germany
Prior art keywords
fractionation
blood plasma
plasma
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484400602T
Other languages
English (en)
Inventor
Adrien Dromard
Michel Exertier
Claude Rollin
Jean-Louis Tayot
Michel Tardy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Recherches SA
Institut Merieux SA
Original Assignee
Rhone Poulenc Recherches SA
Institut Merieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Recherches SA, Institut Merieux SA filed Critical Rhone Poulenc Recherches SA
Application granted granted Critical
Publication of DE3469132D1 publication Critical patent/DE3469132D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/16—Organic material
    • B01J39/17—Organic material containing also inorganic materials, e.g. inert material coated with an ion-exchange resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00—Ion-exchange processes in general; Apparatus therefor
    • B01J47/014—Ion-exchange processes in general; Apparatus therefor in which the adsorbent properties of the ion-exchanger are involved, e.g. recovery of proteins or other high-molecular compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE8484400602T 1983-04-01 1984-03-26 Process for the fractionation of blood plasma Expired DE3469132D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8305441A FR2543448A1 (fr) 1983-04-01 1983-04-01 Procede de fractionnement du plasma

Publications (1)

Publication Number Publication Date
DE3469132D1 true DE3469132D1 (en) 1988-03-10

Family

ID=9287485

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484400602T Expired DE3469132D1 (en) 1983-04-01 1984-03-26 Process for the fractionation of blood plasma

Country Status (16)

Country Link
US (1) US4675384A (de)
EP (1) EP0121468B1 (de)
JP (1) JPS6023320A (de)
AR (1) AR242115A1 (de)
AT (1) ATE32304T1 (de)
AU (1) AU565104B2 (de)
CA (1) CA1203478A (de)
DE (1) DE3469132D1 (de)
DK (1) DK164741C (de)
ES (1) ES8501635A1 (de)
FR (1) FR2543448A1 (de)
IE (1) IE57598B1 (de)
IN (1) IN160634B (de)
MX (1) MX7676E (de)
NO (1) NO166230C (de)
ZA (1) ZA842204B (de)

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US4920152A (en) * 1986-05-13 1990-04-24 Purdue Research Foundation Reversed-phase packing material and method
US4911910A (en) * 1986-11-25 1990-03-27 Biotech Research Labs, Inc. Purified equine immunologlobulins and method of use thereof
US4806346A (en) * 1986-12-16 1989-02-21 American Home Products Corporation Method for isolation of antigen specific immunoglobulin
US4897197A (en) * 1987-06-17 1990-01-30 Dow Corning Corporation Using liquid chromatography packing materials
US4773994A (en) * 1987-06-17 1988-09-27 Dow Corning Corporation Liquid chromatography packing materials
US4778600A (en) * 1987-06-17 1988-10-18 Dow Corning Corporation Liquid chromatography dual zone packing materials
US4855054A (en) * 1987-06-17 1989-08-08 Dow Corning Corporation Using liquid chromatography dual zone packing materials
US4941974A (en) * 1987-06-17 1990-07-17 Dow Corning Corporation Method of making liquid chromatography dual zone packing materials
US4959340A (en) * 1987-06-17 1990-09-25 Dow Corning Corporation Method of making liquid chromatography packing materials
US4950635A (en) * 1988-02-11 1990-08-21 Dow Corning Corporation Method for producing dual zone materials by catalyzed halosilylation
US4950634A (en) * 1988-02-11 1990-08-21 Dow Corning Corporation Method for producing dual zone materials by use of an organosilane mixture
US5277818A (en) * 1988-10-31 1994-01-11 The Green Cross Corporation Albumin preparation and process for preparing the same
JP3554796B2 (ja) * 1988-10-31 2004-08-18 三菱ウェルファーマ株式会社 アルブミン製剤及びその製造方法
FR2648048B1 (fr) * 1989-06-08 1994-06-03 Lille Transfusion Sanguine Procede de preparation de solutions d'albumine purifiee
GB8913183D0 (en) * 1989-06-08 1989-07-26 Central Blood Lab Authority Chemical products
US5215908A (en) * 1989-06-13 1993-06-01 Genencor International, Inc. Process for recovery and purification of chymosin
JPH0768137B2 (ja) * 1989-06-15 1995-07-26 株式会社ミドリ十字 アルブミン製剤及びその製法
US5250662A (en) * 1989-10-05 1993-10-05 Alpha Therapeutic Corporation Albumin purification
ES2224094T3 (es) * 1990-04-19 2005-03-01 Bayer Corporation Procedimiento para preparar seroalbumina normal (humana) esencialmente monomerica.
AT402261B (de) * 1991-01-25 1997-03-25 Immuno Ag Komplex enthaltend den gerinnungsfaktor ix
FR2672604B1 (fr) * 1991-02-07 1995-05-05 Pasteur Merieux Serums Vacc Procede pour isoler de l'albumine humaine a partir du surnageant iv, notamment iv-4, ou de la fraction v de cohn ou d'un surnageant ou fraction analogue.
US5186838A (en) * 1991-03-04 1993-02-16 Biotage Inc. Chromatographic packing material having functionalized polymeric coating on a substrate
CA2102425A1 (en) * 1991-03-04 1992-09-05 Ethan S. Simon Butadiene acrylonitrile polymeric coating and chromatographic packing material
US5167822A (en) * 1991-03-04 1992-12-01 Biotage Inc. Butadiene acrylonitrile polymeric coating for chromatographic packing material
EP0933083A1 (de) * 1991-07-12 1999-08-04 Dsm N.V. Verfahren zur Reinigung von Serumalbumin
US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
ES2046122B1 (es) * 1992-06-04 1994-10-01 Grifols Grupo Sa Procedimiento para la obtencion de albumina serica humana purificada.
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
US5512169A (en) * 1992-12-30 1996-04-30 Dow Corning Corporation Liquid column packing materials
FR2706466B1 (fr) * 1993-06-14 1995-08-25 Aetsrn Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré.
US5486293A (en) * 1994-03-21 1996-01-23 Hemasure, Inc. Removal of small exogenous molecules from biological fluids
JP3702474B2 (ja) 1994-06-01 2005-10-05 三菱ウェルファーマ株式会社 血清アルブミン製剤の製造方法
US6114466A (en) * 1998-02-06 2000-09-05 Renal Tech International Llc Material for purification of physiological liquids of organism
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
AUPP971399A0 (en) * 1999-04-12 1999-05-06 Life Therapeutics Limited Separation of plasma components
US6833238B2 (en) * 2002-01-04 2004-12-21 Applera Corporation Petal-array support for use with microplates
US20040016702A1 (en) * 2002-07-26 2004-01-29 Applera Corporation Device and method for purification of nucleic acids
US6861473B2 (en) * 2003-02-28 2005-03-01 Baxter International Inc. Macromolecular ketoaldehydes
US20050181378A1 (en) * 2004-02-18 2005-08-18 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
US20060160122A1 (en) * 2004-02-18 2006-07-20 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
US20050196856A1 (en) * 2004-02-18 2005-09-08 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
US7879332B2 (en) * 2005-09-01 2011-02-01 Plasma Technologies, Llc Ultra-high yield intravenous immune globulin preparation
US20070049732A1 (en) * 2005-09-01 2007-03-01 Zurlo Eugene J Ultra-high yield intravenous immune globulin preparation
US8293242B2 (en) * 2005-09-01 2012-10-23 Plasma Technologies, Llc Ultra-high yield of alpha-1-anti-trypsin
US20090118381A1 (en) * 2006-12-04 2009-05-07 Berkeley Heartlab, Inc. Separation of High Density Lipoproteins on Polymer Monoliths with Decreased Hydrophobicity
DE102007038413A1 (de) * 2007-08-09 2009-02-12 Beiersdorf Ag Kosmetische Emulgatorkombination
FR2952639B1 (fr) * 2009-11-16 2013-08-30 Lab Francais Du Fractionnement Procede de purification de facteur b
US20140031527A1 (en) * 2012-07-27 2014-01-30 Csl Limited Method for polishing albumin
IN2015DN03308A (de) 2012-11-13 2015-10-09 Ge Healthcare Bio Sciences Ab
EP2735360B1 (de) * 2012-11-26 2017-04-12 Gambro Lundia AB Adsorptionsvorrichtung umfassend eine Kombinationen aus Hohlfasermembranen und Beads
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma
EP2985076B1 (de) * 2014-08-15 2022-03-30 Merck Patent GmbH Reinigung von immunoglobulinen aus plasma
FR3040882A1 (fr) * 2015-09-10 2017-03-17 Lab Francais Du Fractionnement Composition liquide d'albumine humaine a usage therapeutique

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1009217A (en) * 1972-10-03 1977-04-26 Frederick Grosser Insoluble crosslinked homopolymers and copolymers, polymerized on an inert substrate
US3941718A (en) * 1972-10-03 1976-03-02 Gaf Corporation Insoluble crosslinked homopolymers and copolymers, polymerized on an inert substrate
US4025500A (en) * 1974-06-06 1977-05-24 Baxter Laboratories, Inc. Preparation of albumin by fractionation of blood plasma or serum
LU73094A1 (de) * 1975-07-29 1977-03-24
FR2321932A1 (fr) * 1975-08-28 1977-03-25 Rhone Poulenc Ind Procede de separation de proteines par echange d'ions
FR2359634A2 (fr) * 1976-07-28 1978-02-24 Rhone Poulenc Ind Procede de separation de proteines par echange d'ions
SE405549B (sv) * 1975-10-09 1978-12-18 Pharmacia Fine Chemicals Ab Forfarande for isolering av albumin ur plasmaprodukter genom kromatografisk fraktionering
US4229342A (en) * 1977-05-18 1980-10-21 Rhone-Poulenc Industries Process for extracting proteins from milk using silica and anion exchange resins
US4136094A (en) * 1977-08-31 1979-01-23 The Regents Of The University Of Minnesota Preparation of intravenous human and animal gamma globulins and isolation of albumin
FR2403098A1 (fr) * 1977-09-19 1979-04-13 Merieux Inst Nouveau materiau capable de fixer de facon reversible des macromolecules biologiques, sa preparation et son application
US4176056A (en) * 1978-04-27 1979-11-27 Pennwalt Corporation Cyclic operation of a bed of mixed ion exchange resins
US4228154A (en) * 1979-02-26 1980-10-14 Armour Pharmaceutical Company Purification of plasma albumin by ion exchange chromatography
JPH115684A (ja) * 1997-06-13 1999-01-12 Nissei Eng:Kk チャック吊り上げ装置

Also Published As

Publication number Publication date
IN160634B (de) 1987-07-18
DK174484A (da) 1984-10-02
AU565104B2 (en) 1987-09-03
DK164741C (da) 1992-12-28
NO841266L (no) 1984-10-02
ES531132A0 (es) 1984-12-01
ZA842204B (en) 1984-10-31
ES8501635A1 (es) 1984-12-01
IE840802L (en) 1984-10-01
AR242115A1 (es) 1993-03-31
IE57598B1 (en) 1993-01-27
NO166230B (no) 1991-03-11
DK164741B (da) 1992-08-10
EP0121468A2 (de) 1984-10-10
DK174484D0 (da) 1984-03-30
CA1203478A (fr) 1986-04-22
JPS6023320A (ja) 1985-02-05
MX7676E (es) 1990-08-02
EP0121468B1 (de) 1988-02-03
AU2626484A (en) 1984-10-04
US4675384A (en) 1987-06-23
JPH0520439B2 (de) 1993-03-19
NO166230C (no) 1991-06-19
ATE32304T1 (de) 1988-02-15
FR2543448A1 (fr) 1984-10-05
EP0121468A3 (en) 1985-07-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PATENTANWAELTE GESTHUYSEN, VON ROHR & EGGERT, 45128