DE3486313D1 - Übertragung von Makromolekülen von einem chromatographischen Substrat zu einer immobilisierenden Matrize. - Google Patents

Übertragung von Makromolekülen von einem chromatographischen Substrat zu einer immobilisierenden Matrize.

Info

Publication number
DE3486313D1
DE3486313D1 DE3486313T DE3486313T DE3486313D1 DE 3486313 D1 DE3486313 D1 DE 3486313D1 DE 3486313 T DE3486313 T DE 3486313T DE 3486313 T DE3486313 T DE 3486313T DE 3486313 D1 DE3486313 D1 DE 3486313D1
Authority
DE
Germany
Prior art keywords
macromolecules
transfer
chromatographic substrate
immobilizing
template
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE3486313T
Other languages
English (en)
Other versions
DE3486313T2 (de
Inventor
Jonathan M Gershoni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23844591&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3486313(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yale University filed Critical Yale University
Application granted granted Critical
Publication of DE3486313D1 publication Critical patent/DE3486313D1/de
Publication of DE3486313T2 publication Critical patent/DE3486313T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0093—Chemical modification
    • B01D67/00931—Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0093—Chemical modification
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
    • B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/56—Polyamides, e.g. polyester-amides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/30—Cross-linking
DE3486313T 1983-02-07 1984-01-27 Übertragung von Makromolekülen von einem chromatographischen Substrat zu einer immobilisierenden Matrize. Revoked DE3486313T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/464,609 US4512896A (en) 1983-02-07 1983-02-07 Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix

Publications (2)

Publication Number Publication Date
DE3486313D1 true DE3486313D1 (de) 1994-07-07
DE3486313T2 DE3486313T2 (de) 1994-11-10

Family

ID=23844591

Family Applications (2)

Application Number Title Priority Date Filing Date
DE84900827T Revoked DE3486231T2 (de) 1983-02-07 1984-01-27 Übertragung von makromolekülen vom chromatographischen substrat zur immobilisierenden matrize.
DE3486313T Revoked DE3486313T2 (de) 1983-02-07 1984-01-27 Übertragung von Makromolekülen von einem chromatographischen Substrat zu einer immobilisierenden Matrize.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE84900827T Revoked DE3486231T2 (de) 1983-02-07 1984-01-27 Übertragung von makromolekülen vom chromatographischen substrat zur immobilisierenden matrize.

Country Status (9)

Country Link
US (1) US4512896A (de)
EP (1) EP0138841B1 (de)
JP (1) JPS60501126A (de)
AU (1) AU577276B2 (de)
CA (1) CA1207737A (de)
DE (2) DE3486231T2 (de)
FR (1) FR2540629B1 (de)
IL (1) IL70866A (de)
WO (1) WO1984003055A1 (de)

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US4601828A (en) * 1983-02-07 1986-07-22 Yale University Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix
USRE38435E1 (en) * 1983-12-28 2004-02-24 Daicel Chemical Industries, Ltd. Separating agent
USRE34457E (en) * 1983-12-28 1993-11-30 Daicel Chemical Industries, Inc. Separating agent
JPS60142930A (ja) * 1983-12-28 1985-07-29 Daicel Chem Ind Ltd 分離剤
FR2586689B1 (fr) * 1985-09-02 1990-06-08 Plant Genetic Systems Nv Moyens et procedes de transfert de proteines sur une surface receptrice supportee
EP0214909A1 (de) * 1985-09-02 1987-03-18 Plant Genetic Systems N.V. Mittel und Verfahren zur Übertragung von Proteinen und/oder Nukleinsäuren auf eine unterstützte Rezeptoroberfläche
US4806546A (en) * 1985-09-30 1989-02-21 Miles Inc. Immobilization of nucleic acids on derivatized nylon supports
US4997537A (en) * 1986-10-21 1991-03-05 Northeastern University High performance microcapillary gel electrophoresis
US5665216A (en) * 1986-10-21 1997-09-09 Northeastern University Capillary column for high performance electrophoretic separation and detection of SDS proteins and system and using the same
DE3736087C2 (de) * 1987-10-24 1997-03-06 Serva Feinbiochem Gmbh & Co Gewebe zur Herstellung von Elektrophoresegelen
US5114585A (en) * 1988-03-01 1992-05-19 Gelman Sciences, Inc. Charged porous filter
DE68919706T2 (de) * 1988-05-10 1995-04-13 Du Pont Verfahren zum schnellen nachweis von nukleinsäuren.
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5004543A (en) * 1988-06-21 1991-04-02 Millipore Corporation Charge-modified hydrophobic membrane materials and method for making the same
US5075220A (en) * 1988-10-07 1991-12-24 Eastman Kodak Company Determination of a chlamydial or gonococcal antigen using a positively-charged ionically binding support
US5004806A (en) * 1988-10-17 1991-04-02 Molecular Devices Corporation Nitrocellulose filtration to remove proteins from polynucleotides
US5683916A (en) * 1988-10-31 1997-11-04 Hemasure Inc. Membrane affinity apparatus and purification methods related thereto
US4957620A (en) * 1988-11-15 1990-09-18 Hoechst Celanese Corporation Liquid chromatography using microporous hollow fibers
US4981591A (en) * 1989-04-07 1991-01-01 Cuno, Incorporated Cationic charge modified filter media
GB8921818D0 (en) * 1989-09-27 1989-11-08 Astromed Ltd Treatment of carbohydrates
US5269931A (en) * 1990-09-17 1993-12-14 Gelman Sciences Inc. Cationic charge modified microporous membranes
US5151189A (en) * 1990-09-17 1992-09-29 Gelman Sciences, Inc. Cationic charge modified microporous membrane
US5543054A (en) * 1993-11-24 1996-08-06 Millipore Corporation Method and apparatus for covalent immobilization of charge- conjugated carbohydrate molecules
US5728301A (en) * 1994-09-29 1998-03-17 Truett; William L. Apparatus and method for thin layer chromatography
US5714359A (en) * 1995-10-12 1998-02-03 The University Of Akron Apparatus and method for electrostatic endothelial cell seeding in a vascular prosthesis
US6010573A (en) * 1998-07-01 2000-01-04 Virginia Commonwealth University Apparatus and method for endothelial cell seeding/transfection of intravascular stents
JP2000180442A (ja) * 1998-12-15 2000-06-30 Fuji Photo Film Co Ltd 血液濾過器
US6780327B1 (en) 1999-02-25 2004-08-24 Pall Corporation Positively charged membrane
US6680208B1 (en) * 1999-11-19 2004-01-20 Becton, Dickinson And Company Rapid protein identification using antibody mixtures
CA2443842A1 (en) * 2001-04-10 2002-10-24 Children's Medical Center Corporation Methods of analysis and labeling of protein-protein interactions
US20030038081A1 (en) * 2001-08-14 2003-02-27 I-Fan Wang High strength asymmetric cellulosic membrane
US20030036085A1 (en) * 2002-08-19 2003-02-20 Salinaro Richard F Membranes
US7479222B2 (en) * 2004-02-05 2009-01-20 Millipore Corporation Porous adsorptive or chromatographic media
WO2006015495A1 (en) * 2004-08-13 2006-02-16 Mcmaster University Composite material comprising a non-crosslinked gel polymer
KR20070062988A (ko) 2004-09-30 2007-06-18 맥마스터 유니버시티 층을 이루는 친수성 코팅을 포함하는 조성 물질
GB0702504D0 (en) * 2007-02-09 2007-03-21 Ge Healthcare Bio Sciences Ab Cross-linked cellulose membranes
US9433922B2 (en) 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
US20090130738A1 (en) * 2007-11-19 2009-05-21 Mikhail Kozlov Media for membrane ion exchange chromatography
US8277649B2 (en) 2009-12-14 2012-10-02 General Electric Company Membranes and associated methods for purification of antibodies
WO2020209267A1 (ja) * 2019-04-08 2020-10-15 旭化成メディカル株式会社 タンパク質含有溶液精製用ポリアミド媒体及びその製造方法
CN111675825B (zh) * 2020-06-09 2022-06-24 大连工业大学 一种附有胰蛋白酶的微孔膜的制备方法及其在蛋白水解中的应用

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US2926154A (en) 1957-09-05 1960-02-23 Hercules Powder Co Ltd Cationic thermosetting polyamide-epichlorohydrin resins and process of making same
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US3224986A (en) 1962-04-18 1965-12-21 Hercules Powder Co Ltd Cationic epichlorohydrin modified polyamide reacted with water-soluble polymers
DE1792083A1 (de) * 1968-07-19 1971-04-29 Merck Anlagen Gmbh Zweischichtenplatte und ihre Verwendung zur duennschichtchromatographischen Auftrennung von Aminosaeuren
US3769968A (en) 1971-11-22 1973-11-06 L Blount Speculum
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US3875044A (en) * 1972-06-09 1975-04-01 Marine Colloids Inc Hydratable gel sheets
US3878100A (en) * 1973-02-01 1975-04-15 Marine Colloids Inc Separation medium
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MX152562A (es) 1978-05-15 1985-08-29 Pall Corp Mejoras a procedimiento para preparar membranas de resina de poliamida insolubles en alcohol,hidrofilicas y sin revestimiento
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US4357311A (en) * 1980-10-03 1982-11-02 Warner-Lambert Company Substrate for immunoassay and means of preparing same
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Also Published As

Publication number Publication date
DE3486313T2 (de) 1994-11-10
IL70866A0 (en) 1984-05-31
EP0138841A1 (de) 1985-05-02
JPS60501126A (ja) 1985-07-18
AU577276B2 (en) 1988-09-22
FR2540629B1 (fr) 1989-09-22
DE3486231T2 (de) 1994-04-14
AU2497884A (en) 1984-08-30
DE3486231D1 (de) 1993-11-25
US4512896A (en) 1985-04-23
WO1984003055A1 (en) 1984-08-16
JPH0376868B2 (de) 1991-12-06
EP0138841B1 (de) 1993-10-20
FR2540629A1 (fr) 1984-08-10
EP0138841A4 (de) 1987-12-01
IL70866A (en) 1987-09-16
CA1207737A (en) 1986-07-15

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation