DE3584209T2 - T-zellenrezeptor, spezifisch für antigenpolypeptide und verwandte polynukleotide. - Google Patents

T-zellenrezeptor, spezifisch für antigenpolypeptide und verwandte polynukleotide.

Info

Publication number
DE3584209T2
DE3584209T2 DE3584209T DE3584209T DE3584209T2 DE 3584209 T2 DE3584209 T2 DE 3584209T2 DE 3584209 T DE3584209 T DE 3584209T DE 3584209 T DE3584209 T DE 3584209T DE 3584209 T2 DE3584209 T2 DE 3584209T2
Authority
DE
Germany
Prior art keywords
specific
cell receptor
related polynucleotides
antigen polypeptides
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3584209T
Other languages
English (en)
Other versions
DE3584209D1 (de
Inventor
Mark Davis
Stephen Hedrick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27079355&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3584209(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Application granted granted Critical
Publication of DE3584209D1 publication Critical patent/DE3584209D1/de
Publication of DE3584209T2 publication Critical patent/DE3584209T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE3584209T 1984-03-01 1985-02-28 T-zellenrezeptor, spezifisch für antigenpolypeptide und verwandte polynukleotide. Expired - Lifetime DE3584209T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58533384A 1984-03-01 1984-03-01
US66380984A 1984-10-22 1984-10-22
PCT/US1985/000367 WO1985003947A1 (en) 1984-03-01 1985-02-28 T-cell receptor-specific for antigen polypeptides and related polynucleotides

Publications (2)

Publication Number Publication Date
DE3584209D1 DE3584209D1 (de) 1994-12-01
DE3584209T2 true DE3584209T2 (de) 1995-05-04

Family

ID=27079355

Family Applications (3)

Application Number Title Priority Date Filing Date
DE3588219T Expired - Lifetime DE3588219T2 (de) 1984-03-01 1985-02-28 T-Zellenrezeptor, spezifisch für Antigenpolypeptide und verwandte Polynukleotide
DE3584209T Expired - Lifetime DE3584209T2 (de) 1984-03-01 1985-02-28 T-zellenrezeptor, spezifisch für antigenpolypeptide und verwandte polynukleotide.
DE0570027T Pending DE570027T1 (de) 1984-03-01 1985-02-28 T-Zellenrezeptor, spezifisch für Antigenpolypeptide und verwandte Polynukleotide.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3588219T Expired - Lifetime DE3588219T2 (de) 1984-03-01 1985-02-28 T-Zellenrezeptor, spezifisch für Antigenpolypeptide und verwandte Polynukleotide

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE0570027T Pending DE570027T1 (de) 1984-03-01 1985-02-28 T-Zellenrezeptor, spezifisch für Antigenpolypeptide und verwandte Polynukleotide.

Country Status (8)

Country Link
US (3) US5316925A (de)
EP (3) EP0570027B1 (de)
JP (7) JPH06225765A (de)
AT (1) ATE188251T1 (de)
DE (3) DE3588219T2 (de)
HK (2) HK1006855A1 (de)
SG (1) SG70553A1 (de)
WO (1) WO1985003947A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713332A (en) * 1984-01-13 1987-12-15 The Ontario Cancer Institute T cell specific CDNA clone
EP0570027B1 (de) 1984-03-01 1999-12-29 The Board Of Trustees Of The Leland Stanford Junior University T-Zellenrezeptor, spezifisch für Antigenpolypeptide und verwandte Polynukleotide
US4874845A (en) * 1984-06-13 1989-10-17 Massachusetts Institute Of Technology T lymphocyte receptor subunit
US4873190A (en) * 1984-06-13 1989-10-10 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor
US5189147A (en) * 1984-06-13 1993-02-23 Massachusetts Institute Of Technology Meterodimeric T lymphocyte receptor antibody
EP0296786B1 (de) * 1987-06-23 1996-10-30 The Board Of Trustees Of The Leland Stanford Junior University Innerhalb des alpha-Locus gelegenes T-Zell-Rezeptor-Gen und DNA-Konstruktionen
US5336603A (en) * 1987-10-02 1994-08-09 Genentech, Inc. CD4 adheson variants
US6710169B2 (en) 1987-10-02 2004-03-23 Genentech, Inc. Adheson variants
US6413516B1 (en) * 1989-03-21 2002-07-02 The Immune Response Corporation Peptides and methods against psoriasis
US6464978B1 (en) 1989-03-21 2002-10-15 The Immune Response Corporation Vaccination and methods against multiple sclerosis resulting from pathogenic responses by specific T cell populations
US5776459A (en) * 1989-07-19 1998-07-07 Connetics Corporation TCR V beta 5 peptides
US5614192A (en) * 1989-07-19 1997-03-25 Connective Therapeutics, Inc. T cell receptor peptides as therapeutics for immune-related disease
US6416971B1 (en) * 1990-05-15 2002-07-09 E.R. Squibb & Sons, Inc. Soluble single chain T cell receptors
US7294712B2 (en) * 1990-06-04 2007-11-13 Aventis Pharma S.A. Nucleotide sequences coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
KR100227303B1 (ko) * 1991-02-12 1999-12-01 장-끌로드 비에이으포스 인체 t 임파구 수용체의 베타 사슬의 가변성 영역을 코딩하는 뉴클레오티드 서열, 대응하는 펩티드 세그먼트 및 진단 및 치료 용도
US5552300A (en) * 1994-01-13 1996-09-03 T Cell Sciences, Inc. T cell antigen receptor V region proteins and methods of preparation thereof
US6451571B1 (en) 1994-05-02 2002-09-17 University Of Washington Thymidine kinase mutants
US5688690A (en) * 1994-09-16 1997-11-18 The Wistar Institute Of Anatomy And Biology Human cytotoxic lymphocyte signal transduction surface protein (P38) and monoclonal antibodies thereto
US6087096A (en) * 1995-11-13 2000-07-11 Dau; Peter C. Method of intrafamily fragment analysis of the T cell receptor α and β chain CDR3 regions
WO1999016885A1 (fr) * 1997-09-26 1999-04-08 Kyowa Hakko Kogyo Co., Ltd. Recepteur de lymphocyte t tueur reconnaissant le vih
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
DE19816129A1 (de) * 1998-04-09 1999-10-14 Dolores Schendel T-Zellrezeptor-Expressionskassette
WO2002046400A2 (en) * 2000-12-08 2002-06-13 The Board Of Trustees Of The University Of Illinois Mutated class ii major histocompatibility proteins
DE10109855A1 (de) * 2001-03-01 2002-09-12 Stanislawski Thomas Polypeptide eines p53-Protein-spezifischen murinen alpha/beta T-Zell Rezeptors, diese kodierende Nukleinsäuren und deren Verwendung
US20030199092A1 (en) * 2002-01-11 2003-10-23 The Regents Of The University Of California Methods for increasing mRNA half-life in eukaryotic cells
JP4937138B2 (ja) 2005-01-05 2012-05-23 エフ−シュタール・ビオテヒノロギシェ・フォルシュングス−ウント・エントヴィックルングスゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 相補性決定領域とは異なる分子の領域に設計された結合性を持つ合成免疫グロブリンドメイン
US20080064631A1 (en) * 2006-01-13 2008-03-13 Jeffrey Molldrem T-cell receptors for use in diagnosis and therapy of cancers and autoimmune disease
AT503889B1 (de) 2006-07-05 2011-12-15 Star Biotechnologische Forschungs Und Entwicklungsges M B H F Multivalente immunglobuline
WO2008097926A2 (en) * 2007-02-02 2008-08-14 Yale University Transient transfection with rna
US9249423B2 (en) 2007-02-02 2016-02-02 Yale University Method of de-differentiating and re-differentiating somatic cells using RNA
US10155038B2 (en) 2007-02-02 2018-12-18 Yale University Cells prepared by transient transfection and methods of use thereof
US20100285984A1 (en) * 2007-09-28 2010-11-11 Wettstein Peter J Assessing t cell repertoires
EP2098536A1 (de) 2008-03-05 2009-09-09 4-Antibody AG Isolation und Identifikation antigen- oder ligandenspezifischer Bindungsproteine
EP2113255A1 (de) 2008-05-02 2009-11-04 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Zytotoxisches Immunglobulin
JP5829606B2 (ja) * 2009-06-29 2015-12-09 カリフォルニア・インスティテュート・オブ・テクノロジーＣａｌｉｆｏｒｎｉａ Ｉｎｓｔｉｔｕｔｅ Ｏｆｔｅｃｈｎｏｌｏｇｙ 単一細胞からの未知の再配列されたｔ細胞受容体の単離
EP3172325B1 (de) 2014-07-22 2023-06-28 The University of Notre Dame du Lac Molekulare konstrukte und verwendungen davon

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468464A (en) * 1974-11-04 1984-08-28 The Board Of Trustees Of The Leland Stanford Junior University Biologically functional molecular chimeras
US4363877B1 (en) * 1977-09-23 1998-05-26 Univ California Recombinant dna transfer vectors
US4356270A (en) * 1977-11-08 1982-10-26 Genentech, Inc. Recombinant DNA cloning vehicle
US4394443A (en) * 1980-12-18 1983-07-19 Yale University Method for cloning genes
US4446235A (en) * 1982-03-22 1984-05-01 Genentech, Inc. Method for cloning human growth hormone varient genes
US4550086A (en) * 1983-02-16 1985-10-29 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies that recognize human T cells
US4713332A (en) * 1984-01-13 1987-12-15 The Ontario Cancer Institute T cell specific CDNA clone
US4923799A (en) * 1984-02-06 1990-05-08 The Ontario Cancer Institute T cell specific cDNA clone
US4873190A (en) * 1984-06-13 1989-10-10 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor
EP0570027B1 (de) * 1984-03-01 1999-12-29 The Board Of Trustees Of The Leland Stanford Junior University T-Zellenrezeptor, spezifisch für Antigenpolypeptide und verwandte Polynukleotide
US4874845A (en) * 1984-06-13 1989-10-17 Massachusetts Institute Of Technology T lymphocyte receptor subunit

Also Published As

Publication number Publication date
SG70553A1 (en) 2000-02-22
JPH1067675A (ja) 1998-03-10
US5316925A (en) 1994-05-31
DE3588219T2 (de) 2000-05-18
HK1006855A1 (en) 1999-03-19
EP0174366B1 (de) 1994-10-26
DE570027T1 (de) 1994-11-17
ATE188251T1 (de) 2000-01-15
WO1985003947A1 (en) 1985-09-12
JPH10114672A (ja) 1998-05-06
DE3584209D1 (de) 1994-12-01
JPH09121871A (ja) 1997-05-13
DE3588219D1 (de) 2000-02-03
EP0174366A4 (de) 1987-03-26
US6180104B1 (en) 2001-01-30
JPH07274976A (ja) 1995-10-24
EP0609901A1 (de) 1994-08-10
EP0570027B1 (de) 1999-12-29
JPH1146779A (ja) 1999-02-23
JPH10210992A (ja) 1998-08-11
HK1013844A1 (en) 1999-09-10
JPH06225765A (ja) 1994-08-16
EP0174366A1 (de) 1986-03-19
EP0570027A1 (de) 1993-11-18
US5840304A (en) 1998-11-24

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