DE3588043D1 - Cytokeratin-tumormarkierer und test zu deren nachweis. - Google Patents

Cytokeratin-tumormarkierer und test zu deren nachweis.

Info

Publication number
DE3588043D1
DE3588043D1 DE3588043T DE3588043T DE3588043D1 DE 3588043 D1 DE3588043 D1 DE 3588043D1 DE 3588043 T DE3588043 T DE 3588043T DE 3588043 T DE3588043 T DE 3588043T DE 3588043 D1 DE3588043 D1 DE 3588043D1
Authority
DE
Germany
Prior art keywords
detect
test
neoplastic
tumor marker
cytokeratin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3588043T
Other languages
English (en)
Other versions
DE3588043T2 (de
Inventor
Robert Cardiff
Paul Rossitto
Alan Brabon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
University of California Berkeley
Original Assignee
University of California
University of California Berkeley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24273031&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3588043(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of California, University of California Berkeley filed Critical University of California
Publication of DE3588043D1 publication Critical patent/DE3588043D1/de
Application granted granted Critical
Publication of DE3588043T2 publication Critical patent/DE3588043T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4742—Keratin; Cytokeratin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/828—Cancer
DE3588043T 1984-01-06 1985-01-03 Cytokeratin-tumormarkierer und test zu deren nachweis. Expired - Lifetime DE3588043T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56886284A 1984-01-06 1984-01-06
PCT/US1985/000010 WO1985003132A1 (en) 1984-01-06 1985-01-03 Cytokeratin tumor markers and assays for their detection

Publications (2)

Publication Number Publication Date
DE3588043D1 true DE3588043D1 (de) 1995-08-31
DE3588043T2 DE3588043T2 (de) 1996-03-21

Family

ID=24273031

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3588043T Expired - Lifetime DE3588043T2 (de) 1984-01-06 1985-01-03 Cytokeratin-tumormarkierer und test zu deren nachweis.

Country Status (7)

Country Link
US (1) US4775620A (de)
EP (1) EP0167616B1 (de)
JP (5) JP2723203B2 (de)
AT (1) ATE125626T1 (de)
CA (1) CA1336171C (de)
DE (1) DE3588043T2 (de)
WO (1) WO1985003132A1 (de)

Families Citing this family (40)

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GR850552B (de) * 1984-03-07 1985-07-05 Du Pont
ATE86261T1 (de) * 1986-04-17 1993-03-15 Hybritech Inc Tumorassoziiertes antigen.
DE3786695T2 (de) * 1986-04-17 1993-12-16 Hybritech Inc Tumorassoziiertes Antigen.
FR2606033B1 (fr) * 1986-10-31 1988-12-16 Cird Proteine cytoplasmique des cellules suprabasales de l'epiderme, anticorps capables de reconnaitre cette proteine, et lignees cellulaires hybrides capables de secreter de tels anticorps
FR2606034B1 (fr) * 1986-10-31 1989-06-02 Cird Nouvelle proteine de surface des cellules basales de l'epiderme, anticorps capables de reconnaitre cette proteine, et leur utilisation, et lignees cellulaires hybrides capables de secreter de tels anticorps
DE3815932A1 (de) * 1988-01-26 1989-08-03 Progen Biotechnik Gmbh Verfahren zur identifizierung des ursprungs einer zellgewebsprobe
US5660994A (en) * 1986-11-10 1997-08-26 Progen Biotechnik Gmbh Method of detecting tissue-specific, insoluble cytoskeletal proteins
DE3923951A1 (de) * 1989-07-19 1991-01-31 Boehringer Mannheim Gmbh Verfahren zum nachweis von leberzirrhose
US5411868A (en) * 1989-10-24 1995-05-02 Board Of Regents, The University Of Texas System Diagnostic and premonitoring uses of a 65 kDa tumor-associated protein in companion and domestic animal malignancy
DE3942999C2 (de) * 1989-12-27 1997-12-18 Progen Biotechnik Gmbh Verfahren zum Nachweis von malignen Erkrankungen
DE4023945A1 (de) * 1990-07-27 1992-01-30 Progen Biotechnik Gmbh Verfahren zur reinigung von cytokeratin 20 und dessen verwendung zur erzeugung von antikoerpern
SE470273B (sv) * 1990-09-24 1993-12-20 Idl Immunodeveloplab Ab Cytokeratinfragment, deras framställning och användning, framställning av monoklonala antikroppar och testkit för epitelialcancer
US5547928A (en) * 1993-12-17 1996-08-20 Matritech, Inc. Methods and compositions for the detection of colon cancers
SE9500023L (sv) * 1994-05-17 1995-11-18 Beki Ab Sätt att detektera cancer
US5914238A (en) * 1996-06-05 1999-06-22 Matritech, Inc. Materials and methods for detection of breast cancer
US5858683A (en) 1996-08-30 1999-01-12 Matritech, Inc. Methods and compositions for the detection of cervical cancer
US6168779B1 (en) * 1997-09-16 2001-01-02 The Regents Of The University Of California Methods and kits for identifying ductal orifices
US6890311B2 (en) 1997-09-16 2005-05-10 The Regents Of The University Of California Methods for performing medical procedures within a breast duct
JP2002503814A (ja) 1998-02-12 2002-02-05 イムニベスト・コーポレイション 循環ガン細胞の迅速かつ効率的な単離のための方法および試薬
GB9905817D0 (en) * 1999-03-12 1999-05-05 Oxford Glycosciences Uk Ltd Methods
ATE403154T1 (de) * 1999-04-13 2008-08-15 Wilex Ag Diagnostischer und therapeutischer einsatz von antikörpern gegen den urokinase-rezeptor
EP1208381A2 (de) * 1999-08-13 2002-05-29 Oxford GlycoSciences (UK) Limited Verfahren zum nachweis von brustkrebs
AU2596901A (en) * 1999-12-21 2001-07-03 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
GB0004576D0 (en) * 2000-02-25 2000-04-19 Oxford Glycosciences Uk Ltd Proteins
DE10130985B4 (de) * 2001-06-27 2004-03-18 B.R.A.H.M.S Ag Verfahren zur Diagnose von Sepsis und schweren Infektionen unter Bestimmung löslicher Cytokeratin-1-Fragmente
JP4302518B2 (ja) 2001-08-31 2009-07-29 ケラテク リミテッド 可溶性ｓ−スルホン化ケラチン誘導体からの生体高分子材料の薄膜、繊維、発泡体又は接着剤の製造
WO2003024191A2 (en) * 2001-09-21 2003-03-27 Raven Biotechnologies, Inc. Antibodies that bind to cancer-associated antigen cytokeratin 8 and methods of use thereof
US7630403B2 (en) * 2002-03-08 2009-12-08 Texas Instruments Incorporated MAC aggregation frame with MSDU and fragment of MSDU
NZ550755A (en) * 2002-06-10 2009-06-26 Keratec Ltd Orthopaedic materials derived from keratin
EP1572132A4 (de) * 2002-11-28 2008-10-08 Keratec Ltd Keratinhaltige körperpflegeformulationen
US7767756B2 (en) * 2003-09-19 2010-08-03 Keraplast Technologies, Ltd. Composite materials containing keratin
WO2005043166A1 (ja) * 2003-10-30 2005-05-12 Sysmex Corporation 子宮腺癌の診断薬及び腺癌細胞の検出方法
AU2004298392A1 (en) * 2003-12-19 2005-06-30 Keratec Limited Wound care products containing keratin
US7579317B2 (en) * 2005-03-11 2009-08-25 Keratec, Ltd. Nutraceutical composition comprising soluble keratin or derivative thereof
ES2375453T3 (es) * 2006-09-07 2012-03-01 Universitätsklinikum Hamburg-Eppendorf Método para la detección de células epiteliales cancerosas utilizando citoqueratinas liberadas como marcadores para dichas células.
CA2672069A1 (en) * 2006-12-06 2008-06-12 Keratec, Ltd. Bone void fillers and methods of making the same
CA2672529A1 (en) * 2006-12-11 2008-06-19 Keratec, Ltd. Porous keratin construct and method of making the same
US20080317826A1 (en) * 2007-05-24 2008-12-25 Robert James Kelly Porous keratin constructs, wound healing assemblies and methods using the same
EP2215105A4 (de) * 2007-10-31 2011-06-22 Keraplast Tech Ltd Keratinderivate und verfahren zu deren herstellung
US11090394B1 (en) 2012-03-27 2021-08-17 Florida A&M University Modified nanodelivery system and method for enhanced in vivo medical and preclinical imaging

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150149A (en) * 1976-11-29 1979-04-17 Professional Staff Association Of The Los Angeles County Harbor General Hospital Method and means for the early detection and diagnosis of certain types of cancers
US4229426A (en) * 1978-02-22 1980-10-21 Duke University, Inc. Breast cyst fluid protein assay
US4331647A (en) * 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
CA1190853A (en) * 1981-10-13 1985-07-23 Roberto L. Ceriani Method and compositions for carcinoma diagnosis
CA1215331A (en) * 1983-03-04 1986-12-16 Tsann M. Chu Monoclonal antibodies to human breast carcinoma cells and their use in diagnosis and therapy

Also Published As

Publication number Publication date
JPH0681760B2 (ja) 1994-10-19
CA1336171C (en) 1995-07-04
WO1985003132A1 (en) 1985-07-18
EP0167616A4 (de) 1986-09-04
JP2723203B2 (ja) 1998-03-09
EP0167616A1 (de) 1986-01-15
EP0167616B1 (de) 1995-07-26
JP2537539B2 (ja) 1996-09-25
JP2896362B2 (ja) 1999-05-31
JPS6452800A (en) 1989-02-28
JPS6447392A (en) 1989-02-21
JPH08275778A (ja) 1996-10-22
JP2617289B2 (ja) 1997-06-04
US4775620A (en) 1988-10-04
JPH10123138A (ja) 1998-05-15
JPS61501048A (ja) 1986-05-22
DE3588043T2 (de) 1996-03-21
ATE125626T1 (de) 1995-08-15

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8365 Fully valid after opposition proceedings