DE3588189D1 - Gereinigtes rekombinantes Interleukin-2 enthaltende Zusammensetzungen - Google Patents

Gereinigtes rekombinantes Interleukin-2 enthaltende Zusammensetzungen

Info

Publication number
DE3588189D1
DE3588189D1 DE3588189T DE3588189T DE3588189D1 DE 3588189 D1 DE3588189 D1 DE 3588189D1 DE 3588189 T DE3588189 T DE 3588189T DE 3588189 T DE3588189 T DE 3588189T DE 3588189 D1 DE3588189 D1 DE 3588189D1
Authority
DE
Germany
Prior art keywords
compositions containing
purified recombinant
cellular material
solubilizing
butanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3588189T
Other languages
English (en)
Other versions
DE3588189T2 (de
Inventor
Kirston Edward Koths
James William Thomson
Michael Kunitani
Kenneth Wilson
Wolfgang Helmut Hanisch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24378044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3588189(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of DE3588189D1 publication Critical patent/DE3588189D1/de
Publication of DE3588189T2 publication Critical patent/DE3588189T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE3588189T 1984-03-28 1985-03-27 Gereinigtes rekombinantes Interleukin-2 enthaltende Zusammensetzungen Expired - Lifetime DE3588189T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/594,223 US4569790A (en) 1984-03-28 1984-03-28 Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions

Publications (2)

Publication Number Publication Date
DE3588189D1 true DE3588189D1 (de) 1998-08-20
DE3588189T2 DE3588189T2 (de) 1998-11-19

Family

ID=24378044

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8585103649T Expired - Lifetime DE3586762T2 (de) 1984-03-28 1985-03-27 Gereinigtes rekombinantes interleukin-2 und verfahren zu dessen rueckgewinnung und reinigung.
DE3588189T Expired - Lifetime DE3588189T2 (de) 1984-03-28 1985-03-27 Gereinigtes rekombinantes Interleukin-2 enthaltende Zusammensetzungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE8585103649T Expired - Lifetime DE3586762T2 (de) 1984-03-28 1985-03-27 Gereinigtes rekombinantes interleukin-2 und verfahren zu dessen rueckgewinnung und reinigung.

Country Status (21)

Country Link
US (3) US4569790A (de)
EP (2) EP0470586B1 (de)
JP (2) JP2599903B2 (de)
KR (1) KR850007083A (de)
AT (1) ATE81674T1 (de)
AU (1) AU592751B2 (de)
CA (1) CA1341083C (de)
DE (2) DE3586762T2 (de)
DK (1) DK166324C (de)
ES (1) ES8609362A1 (de)
FI (1) FI94960C (de)
GR (1) GR850741B (de)
HK (1) HK1004474A1 (de)
IE (1) IE59100B1 (de)
IL (1) IL74733A (de)
IN (1) IN162903B (de)
NO (1) NO851235L (de)
NZ (1) NZ211569A (de)
PH (1) PH21012A (de)
PT (1) PT80172B (de)
ZA (1) ZA852347B (de)

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IE850799L (en) 1985-09-28
CA1341083C (en) 2000-08-15
US4569790A (en) 1986-02-11
NO851235L (no) 1985-09-30
DK135985D0 (da) 1985-03-26
EP0470586B1 (de) 1998-07-15
ZA852347B (en) 1986-11-26
JP2648587B2 (ja) 1997-09-03
FI851231A0 (fi) 1985-03-27
ES8609362A1 (es) 1986-09-01
US5614185A (en) 1997-03-25
PT80172A (en) 1985-04-01
PT80172B (pt) 1987-06-17
DK166324B (da) 1993-04-05
AU4046785A (en) 1985-10-03
JP2599903B2 (ja) 1997-04-16
AU592751B2 (en) 1990-01-25
FI94960C (fi) 1995-11-27
GR850741B (de) 1985-06-26
EP0470586A1 (de) 1992-02-12
DE3588189T2 (de) 1998-11-19
DK166324C (da) 1993-08-23
JPH08332089A (ja) 1996-12-17
EP0156373A3 (en) 1987-09-02
ATE81674T1 (de) 1992-11-15
EP0156373A2 (de) 1985-10-02
IL74733A0 (en) 1985-06-30
NZ211569A (en) 1988-05-30
DK135985A (da) 1985-09-29
KR850007083A (ko) 1985-10-30
ES541608A0 (es) 1986-09-01
IE59100B1 (en) 1994-01-12
EP0156373B1 (de) 1992-10-21
IL74733A (en) 1990-11-05
DE3586762T2 (de) 1993-02-25
IN162903B (de) 1988-07-23
DE3586762D1 (de) 1992-11-26
FI94960B (fi) 1995-08-15
FI851231L (fi) 1985-09-29
PH21012A (en) 1987-06-23
HK1004474A1 (en) 1998-11-27
JPS611393A (ja) 1986-01-07
US5419899A (en) 1995-05-30

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