US5866363A
(en)
*
|
1985-08-28 |
1999-02-02 |
Pieczenik; George |
Method and means for sorting and identifying biological information
|
US5824469A
(en)
*
|
1986-07-17 |
1998-10-20 |
University Of Washington |
Method for producing novel DNA sequences with biological activity
|
US20060008806A1
(en)
*
|
1986-07-17 |
2006-01-12 |
University Of Washington |
Method for producing novel DNA sequence with biological activity
|
US5266684A
(en)
|
1988-05-02 |
1993-11-30 |
The Reagents Of The University Of California |
Peptide mixtures
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
CA2009996A1
(en)
*
|
1989-02-17 |
1990-08-17 |
Kathleen S. Cook |
Process for making genes encoding random polymers of amino acids
|
US7413537B2
(en)
|
1989-09-01 |
2008-08-19 |
Dyax Corp. |
Directed evolution of disulfide-bonded micro-proteins
|
ES2118066T3
(es)
*
|
1989-10-05 |
1998-09-16 |
Optein Inc |
Sintesis y aislamiento, exentos de celulas, de nuevos genes y polipeptidos.
|
CA2075974C
(en)
*
|
1990-02-15 |
2001-02-06 |
Dana M. Fowlkes |
Totally synthetic affinity reagents
|
US5747334A
(en)
*
|
1990-02-15 |
1998-05-05 |
The University Of North Carolina At Chapel Hill |
Random peptide library
|
US5498538A
(en)
*
|
1990-02-15 |
1996-03-12 |
The University Of North Carolina At Chapel Hill |
Totally synthetic affinity reagents
|
US5639595A
(en)
*
|
1990-05-01 |
1997-06-17 |
Isis Phamaceuticals, Inc. |
Identification of novel drugs and reagents
|
US5427908A
(en)
*
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
US5972599A
(en)
*
|
1990-06-11 |
1999-10-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of cytokines
|
US6759392B1
(en)
|
1990-06-11 |
2004-07-06 |
Gilead Sciences, Inc. |
High affinity RNA ligands of basic fibroblast growth factor
|
US5853984A
(en)
*
|
1990-06-11 |
1998-12-29 |
Nexstar Pharmaceuticals, Inc. |
Use of nucleic acid ligands in flow cytometry
|
US5637459A
(en)
*
|
1990-06-11 |
1997-06-10 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chimeric selex
|
US5756287A
(en)
*
|
1990-06-11 |
1998-05-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV integrase inhibitors
|
US5731144A
(en)
*
|
1990-06-11 |
1998-03-24 |
Nexstar Pharmaceuticals, Inc. |
High affinity TGFβ nucleic acid ligands
|
US5811533A
(en)
*
|
1990-06-11 |
1998-09-22 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
|
US5693502A
(en)
*
|
1990-06-11 |
1997-12-02 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand inhibitors to DNA polymerases
|
US6177557B1
(en)
|
1990-06-11 |
2001-01-23 |
Nexstar Pharmaceuticals, Inc. |
High affinity ligands of basic fibroblast growth factor and thrombin
|
US5707796A
(en)
*
|
1990-06-11 |
1998-01-13 |
Nexstar Pharmaceuticals, Inc. |
Method for selecting nucleic acids on the basis of structure
|
US5874218A
(en)
*
|
1990-06-11 |
1999-02-23 |
Nexstar Pharmaceuticals, Inc. |
Method for detecting a target compound in a substance using a nucleic acid ligand
|
US5660985A
(en)
|
1990-06-11 |
1997-08-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands containing modified nucleotides
|
US5543293A
(en)
*
|
1990-06-11 |
1996-08-06 |
Nexstar Pharmaceuticals, Inc. |
DNA ligands of thrombin
|
US6011020A
(en)
*
|
1990-06-11 |
2000-01-04 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand complexes
|
US6232071B1
(en)
|
1990-06-11 |
2001-05-15 |
Gilead Sciences, Inc. |
Tenascin-C nucleic acid ligands
|
US5750342A
(en)
*
|
1990-06-11 |
1998-05-12 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands of tissue target
|
US6127119A
(en)
*
|
1990-06-11 |
2000-10-03 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands of tissue target
|
US5637682A
(en)
*
|
1990-06-11 |
1997-06-10 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to the tachykinin substance P
|
US6344321B1
(en)
|
1990-06-11 |
2002-02-05 |
Gilead Sciences, Inc. |
Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met
|
US6083696A
(en)
*
|
1990-06-11 |
2000-07-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands exponential enrichment: blended selex
|
US5668264A
(en)
*
|
1990-06-11 |
1997-09-16 |
Nexstar Pharmaceuticals, Inc. |
High affinity PDGF nucleic acid ligands
|
US5869641A
(en)
*
|
1990-06-11 |
1999-02-09 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of CD4
|
US6569620B1
(en)
|
1990-06-11 |
2003-05-27 |
Somalogic, Inc. |
Method for the automated generation of nucleic acid ligands
|
US5674685A
(en)
*
|
1990-06-11 |
1997-10-07 |
Nexstar Pharmaceuticals, Inc. |
High affinity PDGF nucleic acid ligands
|
US6124449A
(en)
*
|
1990-06-11 |
2000-09-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity TGFβ nucleic acid ligands and inhibitors
|
US5654151A
(en)
*
|
1990-06-11 |
1997-08-05 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV Nucleocapsid nucleic acid ligands
|
US5861254A
(en)
*
|
1997-01-31 |
1999-01-19 |
Nexstar Pharmaceuticals, Inc. |
Flow cell SELEX
|
US5837834A
(en)
*
|
1990-06-11 |
1998-11-17 |
Nexstar Pharmaceuticals, Inc. |
High affinity HKGF nucleic acid ligands and inhibitors
|
US5874557A
(en)
*
|
1990-06-11 |
1999-02-23 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand inhibitors to DNA polymerases
|
US5580737A
(en)
*
|
1990-06-11 |
1996-12-03 |
Nexstar Pharmaceuticals, Inc. |
High-affinity nucleic acid ligands that discriminate between theophylline and caffeine
|
US6346611B1
(en)
|
1990-06-11 |
2002-02-12 |
Gilead Sciences, Inc. |
High affinity TGfβ nucleic acid ligands and inhibitors
|
US5780228A
(en)
*
|
1990-06-11 |
1998-07-14 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands to lectins
|
US5837456A
(en)
*
|
1990-06-11 |
1998-11-17 |
Nexstar Pharmaceuticals, Inc. |
High affinity oligonucleotide ligands to chorionic gonadotropin hormone and related glycoprotein hormones
|
US5496938A
(en)
|
1990-06-11 |
1996-03-05 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands to HIV-RT and HIV-1 rev
|
US5726017A
(en)
*
|
1990-06-11 |
1998-03-10 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV-1 gag nucleic acid ligands
|
US5503978A
(en)
*
|
1990-06-11 |
1996-04-02 |
University Research Corporation |
Method for identification of high affinity DNA ligands of HIV-1 reverse transcriptase
|
US5849890A
(en)
*
|
1990-06-11 |
1998-12-15 |
Nexstar Pharmaceuticals, Inc. |
High affinity oligonucleotide ligands to chorionic gonadotropin hormone and related glycoprotein hormones
|
US6465188B1
(en)
|
1990-06-11 |
2002-10-15 |
Gilead Sciences, Inc. |
Nucleic acid ligand complexes
|
US5270163A
(en)
*
|
1990-06-11 |
1993-12-14 |
University Research Corporation |
Methods for identifying nucleic acid ligands
|
US6001988A
(en)
*
|
1990-06-11 |
1999-12-14 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands to lectins
|
US5763173A
(en)
*
|
1990-06-11 |
1998-06-09 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand inhibitors to DNA polymerases
|
US5567588A
(en)
*
|
1990-06-11 |
1996-10-22 |
University Research Corporation |
Systematic evolution of ligands by exponential enrichment: Solution SELEX
|
US5648214A
(en)
*
|
1990-06-11 |
1997-07-15 |
University Research Corporation |
High-affinity oligonucleotide ligands to the tachykinin substance P
|
US6716580B2
(en)
|
1990-06-11 |
2004-04-06 |
Somalogic, Inc. |
Method for the automated generation of nucleic acid ligands
|
US6610841B1
(en)
|
1997-12-18 |
2003-08-26 |
Gilead Sciences, Inc. |
Nucleotide-based prodrugs
|
US5688935A
(en)
*
|
1990-06-11 |
1997-11-18 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands of tissue target
|
US6001577A
(en)
|
1998-06-08 |
1999-12-14 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
|
US6030776A
(en)
*
|
1990-06-11 |
2000-02-29 |
Nexstar Pharmaceuticals, Inc. |
Parallel SELEX
|
US5962219A
(en)
*
|
1990-06-11 |
1999-10-05 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chemi-selex
|
US5789157A
(en)
*
|
1990-06-11 |
1998-08-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US5686592A
(en)
*
|
1990-06-11 |
1997-11-11 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to immunoglobulin E (IgE)
|
US6696252B2
(en)
|
1990-06-11 |
2004-02-24 |
Gilead Sciences, Inc. |
High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
|
US5846713A
(en)
*
|
1990-06-11 |
1998-12-08 |
Nexstar Pharmaceuticals, Inc. |
High affinity HKGF nucleic acid ligands and inhibitors
|
US5864026A
(en)
*
|
1990-06-11 |
1999-01-26 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US20060084797A1
(en)
*
|
1990-06-11 |
2006-04-20 |
Gilead Sciences, Inc. |
High affinity TGFbeta nucleic acid ligands and inhibitors
|
US20040132067A1
(en)
*
|
1990-06-11 |
2004-07-08 |
Somalogic, Inc. |
Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
|
US5587468A
(en)
*
|
1990-06-11 |
1996-12-24 |
University Research Corporation |
High affinity nucleic acid ligands to HIV integrase
|
US5763566A
(en)
*
|
1990-06-11 |
1998-06-09 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue SELEX
|
US5472841A
(en)
*
|
1990-06-11 |
1995-12-05 |
Nexstar Pharmaceuticals, Inc. |
Methods for identifying nucleic acid ligands of human neutrophil elastase
|
US5795721A
(en)
*
|
1990-06-11 |
1998-08-18 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of ICP4
|
US5635615A
(en)
*
|
1990-06-11 |
1997-06-03 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV nucleocapsid nucleic acid ligands
|
US5731424A
(en)
*
|
1990-06-11 |
1998-03-24 |
Nexstar Pharmaceuticals, Inc. |
High affinity TGFβ nucleic acid ligands and inhibitors
|
US5763177A
(en)
*
|
1990-06-11 |
1998-06-09 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
|
US6261774B1
(en)
*
|
1990-06-11 |
2001-07-17 |
Gilead Sciences, Inc. |
Truncation selex method
|
US6280932B1
(en)
|
1990-06-11 |
2001-08-28 |
Gilead Sciences, Inc. |
High affinity nucleic acid ligands to lectins
|
US5789163A
(en)
*
|
1990-06-11 |
1998-08-04 |
Nexstar Pharmaceuticals, Inc. |
Enzyme linked oligonucleotide assays (ELONAS)
|
US5527894A
(en)
*
|
1990-06-11 |
1996-06-18 |
Nexstar Pharmacueticals, Inc. |
Ligands of HIV-1 tat protein
|
US6395888B1
(en)
|
1996-02-01 |
2002-05-28 |
Gilead Sciences, Inc. |
High affinity nucleic acid ligands of complement system proteins
|
US5766853A
(en)
*
|
1990-06-11 |
1998-06-16 |
Nexstar Pharmaceuticals, Inc. |
Method for identification of high affinity nucleic acid ligands to selectins
|
US6465189B1
(en)
|
1990-06-11 |
2002-10-15 |
Gilead Sciences, Inc. |
Systematic evolution of ligands by exponential enrichment: blended selex
|
US5629155A
(en)
*
|
1990-06-11 |
1997-05-13 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to immunoglobulin E (IgE)
|
US6140490A
(en)
*
|
1996-02-01 |
2000-10-31 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of complement system proteins
|
US5705337A
(en)
*
|
1990-06-11 |
1998-01-06 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chemi-SELEX
|
US5459015A
(en)
*
|
1990-06-11 |
1995-10-17 |
Nexstar Pharmaceuticals, Inc. |
High-affinity RNA ligands of basic fibroblast growth factor
|
CA2084987C
(en)
|
1990-06-11 |
2007-02-13 |
Larry Gold |
Nucleic acid ligands
|
US5683867A
(en)
*
|
1990-06-11 |
1997-11-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: blended SELEX
|
US5712375A
(en)
*
|
1990-06-11 |
1998-01-27 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US6331394B1
(en)
|
1991-06-10 |
2001-12-18 |
Gilead Sciences, Inc. |
Nucleic acid ligands to integrins
|
US5641629A
(en)
*
|
1990-06-11 |
1997-06-24 |
Nexstar Pharmacueticals Inc |
Spectroscopically detectable nucleic acid ligands
|
US5723289A
(en)
*
|
1990-06-11 |
1998-03-03 |
Nexstar Pharmaceuticals, Inc. |
Parallel selex
|
US5723286A
(en)
*
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
GB9015198D0
(en)
*
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US6916605B1
(en)
*
|
1990-07-10 |
2005-07-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US7063943B1
(en)
|
1990-07-10 |
2006-06-20 |
Cambridge Antibody Technology |
Methods for producing members of specific binding pairs
|
US5843701A
(en)
*
|
1990-08-02 |
1998-12-01 |
Nexstar Pharmaceticals, Inc. |
Systematic polypeptide evolution by reverse translation
|
DE69233697T2
(de)
|
1991-03-01 |
2008-01-24 |
Dyax Corp., Cambridge |
Verfahren zur Entwicklung von bindenden Mikroproteinen
|
US6762290B1
(en)
|
1999-07-29 |
2004-07-13 |
Gilead Sciences, Inc. |
High affinity vascular endothelial growth factor (VEGF) receptor nucleic acid ligands and inhibitors
|
US6028186A
(en)
*
|
1991-06-10 |
2000-02-22 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of cytokines
|
AU2313392A
(en)
*
|
1991-08-01 |
1993-03-02 |
University Research Corporation |
Systematic polypeptide evolution by reverse translation
|
US5270170A
(en)
*
|
1991-10-16 |
1993-12-14 |
Affymax Technologies N.V. |
Peptide library and screening method
|
US5733731A
(en)
*
|
1991-10-16 |
1998-03-31 |
Affymax Technologies N.V. |
Peptide library and screening method
|
DK1024191T3
(da)
|
1991-12-02 |
2008-12-08 |
Medical Res Council |
Fremstilling af autoantistoffer fremvist på fag-overflader ud fra antistofsegmentbiblioteker
|
US5656467A
(en)
*
|
1992-01-09 |
1997-08-12 |
The Trustees Of The University Of Pennsylvania |
Methods and materials for producing gene libraries
|
ATE280219T1
(de)
*
|
1992-03-16 |
2004-11-15 |
Jacob Nathaniel Wohlstadter |
Mutagenese und selektionsmethoden in den selben wirtszellen
|
US5869644A
(en)
*
|
1992-04-15 |
1999-02-09 |
The Johns Hopkins University |
Synthesis of diverse and useful collections of oligonucleotidies
|
US5719273A
(en)
*
|
1993-06-14 |
1998-02-17 |
Nexstar Pharmaceuticals, Inc. |
Palladium catalyzed nucleoside modifications methods using nucleophiles and carbon monoxide
|
US5998142A
(en)
*
|
1993-09-08 |
1999-12-07 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chemi-SELEX
|
US6458539B1
(en)
|
1993-09-17 |
2002-10-01 |
Somalogic, Inc. |
Photoselection of nucleic acid ligands
|
CA2173990A1
(en)
*
|
1993-10-12 |
1995-04-20 |
Narasinga Rao |
A library of glyco-peptides useful for identification of cell adhesion inhibitors
|
US20060078561A1
(en)
*
|
1994-01-31 |
2006-04-13 |
The Trustees Of Boston University |
Polyclonal antibody libraries
|
DK0744958T3
(da)
|
1994-01-31 |
2003-10-20 |
Univ Boston |
Polyklonale antistofbiblioteker
|
US5837458A
(en)
|
1994-02-17 |
1998-11-17 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
US6165793A
(en)
*
|
1996-03-25 |
2000-12-26 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6395547B1
(en)
|
1994-02-17 |
2002-05-28 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6995017B1
(en)
|
1994-02-17 |
2006-02-07 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6406855B1
(en)
|
1994-02-17 |
2002-06-18 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
US20060257890A1
(en)
*
|
1996-05-20 |
2006-11-16 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
US6335160B1
(en)
|
1995-02-17 |
2002-01-01 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
US5605793A
(en)
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
US6309883B1
(en)
|
1994-02-17 |
2001-10-30 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
US6117679A
(en)
*
|
1994-02-17 |
2000-09-12 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US7153948B2
(en)
|
1994-04-25 |
2006-12-26 |
Gilead Sciences, Inc. |
High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
|
US6682886B1
(en)
|
1994-04-28 |
2004-01-27 |
Gilead Sciences, Inc. |
Bivalent binding molecules of 7 transmembrane G protein-coupled receptors
|
US6010861A
(en)
*
|
1994-08-03 |
2000-01-04 |
Dgi Biotechnologies, Llc |
Target specific screens and their use for discovering small organic molecular pharmacophores
|
US6048698A
(en)
*
|
1994-09-20 |
2000-04-11 |
Nexstar Pharmaceuticals, Inc. |
Parallel SELEX™
|
US5885577A
(en)
*
|
1994-09-21 |
1999-03-23 |
Cytogen Corporation |
Antigen binding peptides (abtides) from peptide libraries
|
CA2200684A1
(en)
*
|
1994-09-21 |
1996-03-28 |
Cytogen Corporation |
Antigen binding peptides (abtides) from peptide libraries
|
US6013443A
(en)
|
1995-05-03 |
2000-01-11 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue SELEX
|
CA2645735A1
(en)
*
|
1995-05-03 |
1996-11-07 |
Gilead Science, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US5859228A
(en)
*
|
1995-05-04 |
1999-01-12 |
Nexstar Pharmaceuticals, Inc. |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
|
US8071737B2
(en)
|
1995-05-04 |
2011-12-06 |
Glead Sciences, Inc. |
Nucleic acid ligand complexes
|
US5723594A
(en)
*
|
1995-06-07 |
1998-03-03 |
Nexstar Pharmaceuticals, Inc. |
High affinity PDGF nucleic acid ligands
|
EP1741780A3
(de)
|
1995-06-02 |
2007-03-28 |
Gilead Sciences, Inc. |
Ologonukleotidliganden mit höher Affinität für Wachstumsfaktoren
|
US20010053523A1
(en)
*
|
1995-06-02 |
2001-12-20 |
M&E Biotech A/S. |
Method for identification of biologically active peptides and nucleic acids
|
US6229002B1
(en)
|
1995-06-07 |
2001-05-08 |
Nexstar Pharmaceuticlas, Inc. |
Platelet derived growth factor (PDGF) nucleic acid ligand complexes
|
US5797870A
(en)
*
|
1995-06-07 |
1998-08-25 |
Indiana University Foundation |
Pericardial delivery of therapeutic and diagnostic agents
|
US6183967B1
(en)
|
1995-06-07 |
2001-02-06 |
Nexstar Pharmaceuticals |
Nucleic acid ligand inhibitors to DNA polymerases
|
US6699843B2
(en)
|
1995-06-07 |
2004-03-02 |
Gilead Sciences, Inc. |
Method for treatment of tumors using nucleic acid ligands to PDGF
|
US6475806B1
(en)
|
1995-06-07 |
2002-11-05 |
Praecis Pharmaceuticals, Inc. |
Anchor libraries and identification of peptide binding sequences
|
DK0833944T3
(da)
*
|
1995-06-07 |
2009-05-11 |
Gilead Sciences Inc |
Nucleinsyreligander som binder til og inhiberer DNA-polymeraser
|
US20090118481A1
(en)
*
|
1995-06-07 |
2009-05-07 |
Gilead Sciences, Inc. |
High Affinity Nucleic Acid Ligands To Lectins
|
US5965408A
(en)
|
1996-07-09 |
1999-10-12 |
Diversa Corporation |
Method of DNA reassembly by interrupting synthesis
|
US6352842B1
(en)
|
1995-12-07 |
2002-03-05 |
Diversa Corporation |
Exonucease-mediated gene assembly in directed evolution
|
US6358709B1
(en)
|
1995-12-07 |
2002-03-19 |
Diversa Corporation |
End selection in directed evolution
|
US20030219752A1
(en)
*
|
1995-12-07 |
2003-11-27 |
Diversa Corporation |
Novel antigen binding molecules for therapeutic, diagnostic, prophylactic, enzymatic, industrial, and agricultural applications, and methods for generating and screening thereof
|
US6537776B1
(en)
*
|
1999-06-14 |
2003-03-25 |
Diversa Corporation |
Synthetic ligation reassembly in directed evolution
|
US6361974B1
(en)
*
|
1995-12-07 |
2002-03-26 |
Diversa Corporation |
Exonuclease-mediated nucleic acid reassembly in directed evolution
|
US6939689B2
(en)
|
1995-12-07 |
2005-09-06 |
Diversa Corporation |
Exonuclease-mediated nucleic acid reassembly in directed evolution
|
US6740506B2
(en)
|
1995-12-07 |
2004-05-25 |
Diversa Corporation |
End selection in directed evolution
|
US5830696A
(en)
|
1996-12-05 |
1998-11-03 |
Diversa Corporation |
Directed evolution of thermophilic enzymes
|
US7018793B1
(en)
*
|
1995-12-07 |
2006-03-28 |
Diversa Corporation |
Combinatorial screening of mixed populations of organisms
|
US20020164580A1
(en)
*
|
1995-12-07 |
2002-11-07 |
Diversa Corporation |
Combinatorial screening of mixed populations of organisms
|
US6713279B1
(en)
|
1995-12-07 |
2004-03-30 |
Diversa Corporation |
Non-stochastic generation of genetic vaccines and enzymes
|
US20020028443A1
(en)
*
|
1999-09-27 |
2002-03-07 |
Jay M. Short |
Method of dna shuffling with polynucleotides produced by blocking or interrupting a synthesis or amplification process
|
US6365344B1
(en)
*
|
1996-01-23 |
2002-04-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for screening for transdominant effector peptides and RNA molecules
|
DK0877752T3
(da)
*
|
1996-01-23 |
2003-09-15 |
Univ Leland Stanford Junior |
Fremgangsmåder til screening af transdominante effektorpeptider og RNA molekyler
|
US6096548A
(en)
|
1996-03-25 |
2000-08-01 |
Maxygen, Inc. |
Method for directing evolution of a virus
|
US6506602B1
(en)
|
1996-03-25 |
2003-01-14 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6696251B1
(en)
|
1996-05-31 |
2004-02-24 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6300065B1
(en)
|
1996-05-31 |
2001-10-09 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6699658B1
(en)
|
1996-05-31 |
2004-03-02 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6838238B1
(en)
|
1996-10-17 |
2005-01-04 |
Invitrogen Corporation |
Morphatides: novel shape and structure libraries
|
US6426335B1
(en)
*
|
1997-10-17 |
2002-07-30 |
Gilead Sciences, Inc. |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
|
JP2001504328A
(ja)
|
1996-10-31 |
2001-04-03 |
スミスクライン・ビーチャム・コーポレイション |
医薬上使用される化合物と結合するrna標的モチーフの特徴付けおよび選択の方法
|
US20070009930A1
(en)
*
|
1996-12-18 |
2007-01-11 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
US7148054B2
(en)
|
1997-01-17 |
2006-12-12 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
US6326204B1
(en)
|
1997-01-17 |
2001-12-04 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
CA2276064C
(en)
|
1997-01-17 |
2013-12-17 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
WO1998031700A1
(en)
|
1997-01-21 |
1998-07-23 |
The General Hospital Corporation |
Selection of proteins using rna-protein fusions
|
US6261804B1
(en)
*
|
1997-01-21 |
2001-07-17 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
US8207093B2
(en)
*
|
1997-01-21 |
2012-06-26 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
US5871924A
(en)
*
|
1997-01-27 |
1999-02-16 |
Nexstar Pharmaceuticals, Inc. |
Method for the production of ligands capable of facilitating aminoacyl-RNA synthesis
|
US6153410A
(en)
*
|
1997-03-25 |
2000-11-28 |
California Institute Of Technology |
Recombination of polynucleotide sequences using random or defined primers
|
US6180341B1
(en)
|
1997-05-01 |
2001-01-30 |
Board Of Regents, The Universiry Of Texas System |
In vitro scanning saturation mutagenesis of proteins
|
US7087420B1
(en)
|
1997-07-17 |
2006-08-08 |
Cambia |
Microbial β-glucuronidase genes, gene products and uses thereof
|
US6391547B1
(en)
*
|
1997-09-09 |
2002-05-21 |
Center For The Application Of Molecular Biology To International Agriculture |
Microbial β-glucuronidase genes, gene products and uses thereof
|
US6241701B1
(en)
|
1997-08-01 |
2001-06-05 |
Genetronics, Inc. |
Apparatus for electroporation mediated delivery of drugs and genes
|
US6670127B2
(en)
|
1997-09-16 |
2003-12-30 |
Egea Biosciences, Inc. |
Method for assembly of a polynucleotide encoding a target polypeptide
|
AU1449499A
(en)
|
1997-10-31 |
1999-05-24 |
Maxygen, Incorporated |
Modification of virus tropism and host range by viral genome shuffling
|
DK1036198T3
(da)
|
1997-12-08 |
2013-01-02 |
California Inst Of Techn |
Fremgangsmåde til fremstilling af polynukleotid- og polypeptidsekvenser
|
US5989823A
(en)
*
|
1998-09-18 |
1999-11-23 |
Nexstar Pharmaceuticals, Inc. |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
WO2003070984A1
(en)
|
2002-02-15 |
2003-08-28 |
Somalogic, Inc. |
Methods and reagents for detecting target binding by nucleic acid ligands
|
US20030219803A1
(en)
*
|
1997-12-15 |
2003-11-27 |
Somalogic, Incorporated |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
US6261783B1
(en)
|
1997-12-15 |
2001-07-17 |
Gilead Sciences, Inc. |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
US20070166741A1
(en)
|
1998-12-14 |
2007-07-19 |
Somalogic, Incorporated |
Multiplexed analyses of test samples
|
US6759243B2
(en)
|
1998-01-20 |
2004-07-06 |
Board Of Trustees Of The University Of Illinois |
High affinity TCR proteins and methods
|
US7390619B1
(en)
*
|
1998-02-11 |
2008-06-24 |
Maxygen, Inc. |
Optimization of immunomodulatory properties of genetic vaccines
|
US6541011B2
(en)
|
1998-02-11 |
2003-04-01 |
Maxygen, Inc. |
Antigen library immunization
|
FR2782325B1
(fr)
*
|
1998-08-12 |
2002-05-24 |
Proteus |
Procede d'identification de sequences polynucleotidiques et/ou des proteines correspondantes a partir d'un echantillon d'acides nucleiques
|
US7157083B2
(en)
*
|
1998-04-17 |
2007-01-02 |
Surrogate Pharmaceutical Pathways, Llc |
Compositions and methods for treating retroviral infections
|
BR9910174A
(pt)
|
1998-05-01 |
2001-03-06 |
Maxygen Inc |
Processo para se obter um gene recombinante otimizado de resistência à praga, biblioteca, e, processo para se obter um organismo que seja patogênico a uma praga de vegetal
|
US7153655B2
(en)
*
|
1998-06-16 |
2006-12-26 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
|
US6365408B1
(en)
|
1998-06-19 |
2002-04-02 |
Maxygen, Inc. |
Methods of evolving a polynucleotides by mutagenesis and recombination
|
AU5122499A
(en)
|
1998-07-27 |
2000-02-21 |
Genentech Inc. |
Improved transformation efficiency in phage display through modification of a coat protein
|
DE69941193D1
(de)
|
1998-08-17 |
2009-09-10 |
Bristol Myers Squibb Co |
Identifizierung von verbindung-protein wechselwirkungen mit bibliotheken von gekoppelten protein-nukleinsäure-molekülen
|
US6773911B1
(en)
*
|
1998-11-23 |
2004-08-10 |
Amgen Canada Inc. |
Apoptosis-inducing factor
|
US20020055626A1
(en)
*
|
2000-06-09 |
2002-05-09 |
Turner C. Alexander |
Novel human seven transmembrane proteins and polynucleotides encoding the same
|
US6570003B1
(en)
*
|
2001-01-09 |
2003-05-27 |
Lexion Genetics Incorporated |
Human 7TM proteins and polynucleotides encoding the same
|
ATE439437T1
(de)
*
|
1999-01-05 |
2009-08-15 |
Univ Boston |
Verbessertes klonierungsverfahren
|
AU2415200A
(en)
*
|
1999-01-18 |
2000-08-01 |
Maxygen, Inc. |
Methods of populating data structures for use in evolutionary simulations
|
US20030054390A1
(en)
*
|
1999-01-19 |
2003-03-20 |
Maxygen, Inc. |
Oligonucleotide mediated nucleic acid recombination
|
US20030054360A1
(en)
*
|
1999-01-19 |
2003-03-20 |
Larry Gold |
Method and apparatus for the automated generation of nucleic acid ligands
|
US20070065838A1
(en)
*
|
1999-01-19 |
2007-03-22 |
Maxygen, Inc. |
Oligonucleotide mediated nucleic acid recombination
|
US20090130718A1
(en)
*
|
1999-02-04 |
2009-05-21 |
Diversa Corporation |
Gene site saturation mutagenesis
|
US6329145B1
(en)
|
1999-02-09 |
2001-12-11 |
Gilead Science, Inc. |
Determining non-nucleic acid molecule binding to target by competition with nucleic acid ligand
|
US6365377B1
(en)
|
1999-03-05 |
2002-04-02 |
Maxygen, Inc. |
Recombination of insertion modified nucleic acids
|
US6703240B1
(en)
|
1999-04-13 |
2004-03-09 |
Maxygar, Inc. |
Modified starch metabolism enzymes and encoding genes for improvement and optimization of plant phenotypes
|
US7332308B1
(en)
|
1999-05-21 |
2008-02-19 |
The Penn State Research Foundation |
Incrementally truncated nucleic acids and methods of making same
|
US6280943B1
(en)
|
1999-06-17 |
2001-08-28 |
Gilead Sciences, Inc. |
2′-fluoropyrimidine anti-calf intestinal phosphatase nucleic acid ligands
|
IL147336A0
(en)
|
1999-07-07 |
2002-08-14 |
Zymogenetics Inc |
Human cytokine receptor
|
US6387620B1
(en)
*
|
1999-07-28 |
2002-05-14 |
Gilead Sciences, Inc. |
Transcription-free selex
|
ATE428719T1
(de)
*
|
1999-07-29 |
2009-05-15 |
Gilead Sciences Inc |
Nukleinsäureliganden für den hepatozytischen wachstumsfaktor/dispersionsfaktor (hgf/sf) und seines c-met rezeptors
|
US6171795B1
(en)
|
1999-07-29 |
2001-01-09 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands to CD40ligand
|
US7005260B1
(en)
|
2000-01-28 |
2006-02-28 |
Gilead Sciences, Inc. |
Tenascin-C nucleic acid ligands
|
US6506887B1
(en)
|
1999-07-29 |
2003-01-14 |
Somalogic, Incorporated |
Conditional-selex
|
US20020049312A1
(en)
*
|
2000-05-23 |
2002-04-25 |
Turner C. Alexander |
Noel human thrombospondin-like proteins and polynucleotides encoding the same
|
US6797510B1
(en)
*
|
2001-05-24 |
2004-09-28 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US20080050809A1
(en)
*
|
1999-09-28 |
2008-02-28 |
Alejandro Abuin |
Novel human kinases and polynucleotides encoding the same
|
US6841377B1
(en)
*
|
2001-06-13 |
2005-01-11 |
Lexicon Genetics Incorporated |
Human kinase and polynucleotides encoding the same
|
US6777545B2
(en)
|
2001-04-06 |
2004-08-17 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US6586230B1
(en)
*
|
2000-10-27 |
2003-07-01 |
Lexicon Genetics Incorporated |
Human kinase and polynucleotides encoding the same
|
US6759527B2
(en)
|
2001-03-20 |
2004-07-06 |
Lexicon Genetics Incorporated |
Human kinase and polynucleotides encoding the same
|
US6541252B1
(en)
|
2000-05-19 |
2003-04-01 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US6849425B1
(en)
|
1999-10-14 |
2005-02-01 |
Ixsys, Inc. |
Methods of optimizing antibody variable region binding affinity
|
AU784983B2
(en)
*
|
1999-12-15 |
2006-08-17 |
Genentech Inc. |
Shotgun scanning, a combinatorial method for mapping functional protein epitopes
|
US7022479B2
(en)
*
|
2000-01-24 |
2006-04-04 |
Compound Therapeutics, Inc. |
Sensitive, multiplexed diagnostic assays for protein analysis
|
WO2001053539A1
(en)
|
2000-01-24 |
2001-07-26 |
Phylos, Inc. |
Sensitive, multiplexed diagnostic assays for protein analysis
|
AU2001253117B8
(en)
*
|
2000-01-26 |
2006-08-03 |
Lexicon Pharmaceuticals, Inc. |
Human neurexin-like proteins and polynucleotides encoding the same
|
US20050239061A1
(en)
*
|
2000-03-01 |
2005-10-27 |
Marshall William S |
Identification and use of effectors and allosteric molecules for the alteration of gene expression
|
US7514239B2
(en)
|
2000-03-28 |
2009-04-07 |
Amgen Inc. |
Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof
|
WO2001075178A2
(en)
*
|
2000-04-04 |
2001-10-11 |
Enanta Pharmaceuticals, Inc. |
Methods for identifying peptide aptamers capable of altering a cell phenotype
|
US8288322B2
(en)
|
2000-04-17 |
2012-10-16 |
Dyax Corp. |
Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
|
JP5149476B2
(ja)
*
|
2000-04-17 |
2013-02-20 |
ダイアックス コーポレイション |
ペプチドの多種多様なファミリーのメンバーとしての、遺伝的パッケージの提示ライブラリーを構築する方法
|
US20020037506A1
(en)
*
|
2000-04-18 |
2002-03-28 |
Yun Lin |
Aptamer based two-site binding assay
|
US6479262B1
(en)
|
2000-05-16 |
2002-11-12 |
Hercules, Incorporated |
Solid phase enzymatic assembly of polynucleotides
|
US6703495B2
(en)
*
|
2000-06-07 |
2004-03-09 |
Lexicon Genetics Incorporated |
Polynucleotides encoding human transporter protein
|
US6465632B1
(en)
|
2000-06-09 |
2002-10-15 |
Lexicon Genetics Incorporated |
Human phosphatases and polynucleotides encoding the same
|
WO2002000724A2
(en)
|
2000-06-28 |
2002-01-03 |
Amgen, Inc. |
Thymic stromal lymphopoietin receptor molecules and uses thereof
|
US6994963B1
(en)
|
2000-07-10 |
2006-02-07 |
Ambion, Inc. |
Methods for recombinatorial nucleic acid synthesis
|
US20020012982A1
(en)
*
|
2000-07-13 |
2002-01-31 |
Invitrogen Corporation |
Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix
|
WO2002008408A2
(en)
*
|
2000-07-21 |
2002-01-31 |
Trustees Of Boston University |
Modular vector systems
|
AU2001280968A1
(en)
*
|
2000-07-31 |
2002-02-13 |
Menzel, Rolf |
Compositions and methods for directed gene assembly
|
UA81743C2
(uk)
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
AU2001283094A1
(en)
*
|
2000-08-07 |
2002-02-18 |
Sloan-Kettering Institute For Cancer Research |
Method and composition for immunization using mixed pools of mutated nucleic acids or peptides
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
US7288390B2
(en)
|
2000-08-07 |
2007-10-30 |
Centocor, Inc. |
Anti-dual integrin antibodies, compositions, methods and uses
|
WO2002016435A2
(en)
*
|
2000-08-22 |
2002-02-28 |
Lexicon Genetics Incorporated |
Human 7tm proteins and polynucleotides encoding the same
|
AU2001285326A1
(en)
*
|
2000-08-31 |
2002-03-13 |
Lexicon Genetics Incorporated |
Human kinase proteins and polynucleotides encoding the same
|
US6376190B1
(en)
|
2000-09-22 |
2002-04-23 |
Somalogic, Inc. |
Modified SELEX processes without purified protein
|
AU2001296305B2
(en)
*
|
2000-09-26 |
2007-12-06 |
Duke University |
RNA aptamers and methods for identifying the same
|
US20020155460A1
(en)
*
|
2000-10-10 |
2002-10-24 |
Genencor International Inc. |
Information rich libraries
|
AU2002224401B2
(en)
|
2000-10-16 |
2007-12-06 |
Gilead Sciences, Inc. |
Nucleic acid ligands to the prostate specific membrane antigen
|
EP1624062A3
(de)
*
|
2000-10-27 |
2006-02-22 |
Lexicon Genetics Incorporated |
Humane 7tm Proteine und dafür kodierende Polynukleotide
|
CA2427701A1
(en)
*
|
2000-10-30 |
2002-05-10 |
Lexicon Genetics Incorporated |
Human 7tm proteins and polynucleotides encoding the same
|
AU2002228633A1
(en)
|
2000-11-20 |
2002-06-03 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US20020165149A1
(en)
*
|
2000-12-08 |
2002-11-07 |
Kranz David M. |
Mutated class II major histocompatibility proteins
|
WO2002055685A2
(en)
|
2000-12-11 |
2002-07-18 |
Lexicon Genetics Incorporated |
Novel human kinase and polynucleotides encoding the same
|
AU2002232642B2
(en)
*
|
2000-12-12 |
2007-02-01 |
Lexicon Pharmaceuticals, Inc. |
Novel human kinases and uses thereof
|
US6958213B2
(en)
|
2000-12-12 |
2005-10-25 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function
|
JP4860098B2
(ja)
|
2000-12-18 |
2012-01-25 |
ダイアックス、コープ |
遺伝的パッケージの焦点を合わせたライブラリー
|
US6852844B1
(en)
*
|
2000-12-20 |
2005-02-08 |
Lexicon Genetics Incorporated |
Human protocadherin proteins and polynucleotides encoding the same
|
ES2390425T3
(es)
|
2000-12-22 |
2012-11-12 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Uso de moléculas de orientación repulsivas (RGM) y sus moduladores
|
US20020086292A1
(en)
|
2000-12-22 |
2002-07-04 |
Shigeaki Harayama |
Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules
|
WO2002059325A2
(en)
*
|
2000-12-27 |
2002-08-01 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
JP4061043B2
(ja)
|
2000-12-28 |
2008-03-12 |
株式会社ポストゲノム研究所 |
invitro転写/翻訳系によるペプチド等の製造方法
|
JP2004524835A
(ja)
*
|
2001-01-23 |
2004-08-19 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規ヒトキナーゼおよびそれをコードするポリヌクレオチド
|
US7838219B2
(en)
*
|
2001-02-02 |
2010-11-23 |
Novici Biotech Llc |
Method of increasing complementarity in a heteroduplex
|
US20020146732A1
(en)
*
|
2001-02-02 |
2002-10-10 |
Padgett Hal S. |
Method of increasing complementarity in a heteroduplex
|
US7582423B2
(en)
*
|
2001-02-02 |
2009-09-01 |
Novici Biotech Llc |
Population of polynucleotide sequence variants
|
US20040142433A1
(en)
*
|
2001-02-02 |
2004-07-22 |
Padgett Hal S. |
Polynucleotide sequence variants
|
US20020127587A1
(en)
*
|
2001-02-13 |
2002-09-12 |
Domenica Simms |
Methods and compositions for isolation of biological macromolecules
|
US20030175685A1
(en)
*
|
2001-02-22 |
2003-09-18 |
Praecis Pharmaceuticals Inc. |
Methods for identifying peptides which modulate a biological process
|
WO2002070655A2
(en)
|
2001-03-02 |
2002-09-12 |
Zymogenetics, Inc. |
Mouse cytokine receptor
|
US7807408B2
(en)
*
|
2001-03-19 |
2010-10-05 |
President & Fellows Of Harvard College |
Directed evolution of proteins
|
WO2002074978A2
(en)
|
2001-03-19 |
2002-09-26 |
President And Fellows Of Harvard College |
Nucleic acid shuffling
|
CA2443319A1
(en)
*
|
2001-04-06 |
2002-10-17 |
Lexicon Genetics Incorporated |
Novel human kinase and polynucleotides encoding the same
|
US6644173B2
(en)
*
|
2001-04-11 |
2003-11-11 |
Keuring, Incorporated |
Beverage filter cartridge holder
|
AU2002254773B2
(en)
*
|
2001-05-03 |
2005-12-08 |
Rensselaer Polytechnic Institute |
Novel methods of directed evolution
|
WO2002090517A2
(en)
*
|
2001-05-09 |
2002-11-14 |
Lexicon Genetics Incorporated |
Novel human kinases and polynucleotides encoding the same
|
US20020193585A1
(en)
*
|
2001-05-25 |
2002-12-19 |
Walke D. Wade |
Novel human transporter proteins and polynucleotides encoding the same
|
AU2002312059B2
(en)
|
2001-05-25 |
2009-01-15 |
Duke University |
Modulators of pharmacological agents
|
EP1461425B1
(de)
|
2001-05-29 |
2008-02-13 |
Lexicon Pharmaceuticals, Inc. |
Neue menschliche hydroxylasen und diese codierende polynukleotide
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
US20030148380A1
(en)
*
|
2001-06-05 |
2003-08-07 |
Belcher Angela M. |
Molecular recognition of materials
|
US20050164515A9
(en)
*
|
2001-06-05 |
2005-07-28 |
Belcher Angela M. |
Biological control of nanoparticle nucleation, shape and crystal phase
|
US20030113714A1
(en)
*
|
2001-09-28 |
2003-06-19 |
Belcher Angela M. |
Biological control of nanoparticles
|
EP1992643A3
(de)
|
2001-06-20 |
2008-12-10 |
Genentech, Inc. |
Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Tumoren
|
DE10131441A1
(de)
*
|
2001-06-29 |
2003-01-30 |
Henkel Kgaa |
Eine neue Gruppe von alpha-Amylasen sowie ein Verfahren zur Identifizierung und Gewinnung neuer alpha-Amylasen
|
US20040204669A1
(en)
*
|
2001-07-05 |
2004-10-14 |
Hofmann Gunter A. |
Apparatus for electroporation mediated delivery for drugs and genes
|
JP2004533840A
(ja)
*
|
2001-07-06 |
2004-11-11 |
ジェネンテック・インコーポレーテッド |
ファージディスプレイによるpdzドメインリガンド
|
US6943001B2
(en)
*
|
2001-08-03 |
2005-09-13 |
Diversa Corporation |
Epoxide hydrolases, nucleic acids encoding them and methods for making and using them
|
JP2005508619A
(ja)
*
|
2001-08-03 |
2005-04-07 |
ディヴァーサ コーポレイション |
エポキシドヒドロラーゼ、それらをコードした核酸及びそれらの作製法と利用法
|
DE10138753B4
(de)
*
|
2001-08-07 |
2017-07-20 |
Henkel Ag & Co. Kgaa |
Wasch- und Reinigungsmittel mit Hybrid-Alpha-Amylasen
|
US7647184B2
(en)
*
|
2001-08-27 |
2010-01-12 |
Hanall Pharmaceuticals, Co. Ltd |
High throughput directed evolution by rational mutagenesis
|
WO2003024392A2
(en)
|
2001-09-18 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
EP1438400B1
(de)
|
2001-10-01 |
2009-06-17 |
Dyax Corp. |
Mehrkettige eukaryontische display-vektoren und deren verwendungen
|
US20030073104A1
(en)
*
|
2001-10-02 |
2003-04-17 |
Belcher Angela M. |
Nanoscaling ordering of hybrid materials using genetically engineered mesoscale virus
|
WO2003088808A2
(en)
|
2002-04-16 |
2003-10-30 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
EP1840211A1
(de)
|
2001-10-31 |
2007-10-03 |
Danisco A/S |
Pyranoson Dehydratase aus phanerochaete Chrysosporium
|
CN100374457C
(zh)
|
2001-11-14 |
2008-03-12 |
森托科尔公司 |
抗il-6抗体、组合物、方法和用途
|
CA2467836A1
(en)
*
|
2001-11-20 |
2003-09-04 |
Duke University |
Interfacial biomaterials
|
US6768476B2
(en)
*
|
2001-12-05 |
2004-07-27 |
Etenna Corporation |
Capacitively-loaded bent-wire monopole on an artificial magnetic conductor
|
AU2002359761A1
(en)
|
2001-12-18 |
2003-06-30 |
Invenux, Inc. |
Antibiotic compounds
|
WO2003057921A1
(en)
*
|
2001-12-26 |
2003-07-17 |
Sloan Kettering Institute For Cancer Research |
Dna immunization with libraries of minigenes encoding degenerate variants of major histocompatibility class i restricted epitopes
|
EP1575571A4
(de)
|
2002-01-02 |
2008-06-25 |
Genentech Inc |
Zusammensetzungen und verfahren zur diagnose und behandlung eines tumors
|
AU2003210719A1
(en)
*
|
2002-01-28 |
2003-09-02 |
Sloan-Kettering Institute For Cancer Research |
Identification of mutant antigens with enhanced immunogenicity
|
US7078211B2
(en)
*
|
2002-02-01 |
2006-07-18 |
Large Scale Biology Corporation |
Nucleic acid molecules encoding endonucleases and methods of use thereof
|
US20030157495A1
(en)
*
|
2002-02-01 |
2003-08-21 |
Padgett Hal S. |
Nucleic acid molecules encoding CEL I endonuclease and methods of use thereof
|
US7662924B2
(en)
*
|
2002-02-22 |
2010-02-16 |
The Board Of Trustees Of The University Of Illinois |
Beta chain-associated regulator of apoptosis
|
AU2003217693A1
(en)
*
|
2002-02-22 |
2003-09-09 |
Board Of Trustees Of The University Of Illinois |
Beta chain-associated regulator of apoptosis
|
US20030224404A1
(en)
*
|
2002-02-25 |
2003-12-04 |
Manuel Vega |
High throughput directed evolution of nucleic acids by rational mutagenesis
|
WO2003072054A2
(en)
*
|
2002-02-25 |
2003-09-04 |
Cabot Corporation |
Custom ligand design for biomolecular filtration and purification for bioseperation
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
EP1497418B1
(de)
|
2002-04-19 |
2012-10-17 |
Verenium Corporation |
Phospholipasen, diese codierende nukleinsäuren sowie verfahren zu ihrer herstellung und verwendung
|
US7226771B2
(en)
|
2002-04-19 |
2007-06-05 |
Diversa Corporation |
Phospholipases, nucleic acids encoding them and methods for making and using them
|
CA2485506C
(en)
*
|
2002-05-17 |
2012-02-28 |
Alligator Bioscience Ab |
A method for in vitro molecular evolution of protein function
|
EP1513879B1
(de)
*
|
2002-06-03 |
2018-08-22 |
Genentech, Inc. |
Bibliotheken synthetischer antikörperphagen
|
ATE386810T1
(de)
*
|
2002-06-14 |
2008-03-15 |
Dyax Corp |
Rekombination von nukleinsäurebibliotheksmitgliedern
|
US20040022727A1
(en)
*
|
2002-06-18 |
2004-02-05 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
EP1543158B1
(de)
*
|
2002-07-25 |
2011-07-13 |
Archemix Corp. |
Regulierte aptamer-therapeutika
|
BR0313281A
(pt)
|
2002-08-06 |
2007-07-24 |
Verdia Inc |
variantes de ap1 amina oxidase
|
US20040067532A1
(en)
|
2002-08-12 |
2004-04-08 |
Genetastix Corporation |
High throughput generation and affinity maturation of humanized antibody
|
CA2498319A1
(en)
*
|
2002-09-09 |
2004-03-18 |
Nautilus Biotech |
Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
|
US20050202438A1
(en)
*
|
2002-09-09 |
2005-09-15 |
Rene Gantier |
Rational directed protein evolution using two-dimensional rational mutagenesis scanning
|
US20060020396A1
(en)
*
|
2002-09-09 |
2006-01-26 |
Rene Gantier |
Rational directed protein evolution using two-dimensional rational mutagenesis scanning
|
US9303262B2
(en)
|
2002-09-17 |
2016-04-05 |
Archemix Llc |
Methods for identifying aptamer regulators
|
US20050064508A1
(en)
|
2003-09-22 |
2005-03-24 |
Semzyme |
Peptide mediated synthesis of metallic and magnetic materials
|
BRPI0314814C1
(pt)
|
2002-09-27 |
2021-07-27 |
Xencor Inc |
anticorpo compreendendo uma variante de fc
|
JP3447009B1
(ja)
*
|
2002-10-29 |
2003-09-16 |
實 平垣 |
構築物用構成体およびその製造方法
|
JP2006516151A
(ja)
*
|
2002-11-21 |
2006-06-22 |
アーケミックス コーポレイション |
改良された薬力学的特性を有する多価アプタマー治療剤ならびにそれらの作製方法および使用法
|
US20050124565A1
(en)
*
|
2002-11-21 |
2005-06-09 |
Diener John L. |
Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
|
US8853376B2
(en)
|
2002-11-21 |
2014-10-07 |
Archemix Llc |
Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
|
US10100316B2
(en)
|
2002-11-21 |
2018-10-16 |
Archemix Llc |
Aptamers comprising CPG motifs
|
US20040197804A1
(en)
*
|
2002-12-03 |
2004-10-07 |
Keefe Anthony D. |
Method for in vitro selection of 2'-substituted nucleic acids
|
US20050037394A1
(en)
*
|
2002-12-03 |
2005-02-17 |
Keefe Anthony D. |
Method for in vitro selection of 2'-substituted nucleic acids
|
EP1587831A2
(de)
*
|
2002-12-26 |
2005-10-26 |
Applied Research Systems ARS Holding N.V. |
Gespleisste varianten von lgr6
|
AU2004205631A1
(en)
*
|
2003-01-16 |
2004-08-05 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
EP3023498B1
(de)
|
2003-03-06 |
2018-11-28 |
BASF Enzymes LLC |
Amylasen, nukleinsäuren zur codierung davon und verfahren zur herstellung und verwendung davon
|
MX295545B
(es)
|
2003-03-07 |
2012-02-03 |
Diversa Corp |
Hidrolasas, acidos nucleicos que las codifican, y metodos para hacerlas y usarlas.
|
US7592434B2
(en)
|
2003-04-04 |
2009-09-22 |
Verenium Corporation |
Pectate lyases, nucleic encoding them and methods for making and using them
|
US20050250106A1
(en)
*
|
2003-04-24 |
2005-11-10 |
David Epstein |
Gene knock-down by intracellular expression of aptamers
|
WO2004106488A2
(en)
*
|
2003-05-12 |
2004-12-09 |
Potomac Pharmaceuticals, Inc. |
Gene expression suppression agents
|
US9708410B2
(en)
|
2003-05-30 |
2017-07-18 |
Janssen Biotech, Inc. |
Anti-tissue factor antibodies and compositions
|
EP2404931A1
(de)
|
2003-07-02 |
2012-01-11 |
Verenium Corporation |
Glucanasen, Nukleinsäuren, die diese codieren, und Verfahren zu deren Herstellung und Verwendung
|
SI1641822T1
(sl)
|
2003-07-08 |
2013-08-30 |
Genentech, Inc. |
IL-17 A/F heterologni polipeptidi in njihove terapevtske uporabe
|
WO2005012487A2
(en)
*
|
2003-08-01 |
2005-02-10 |
Invitrogen Corporation |
Compositions and methods for preparing short rna molecules and other nucleic acids
|
KR20060069825A
(ko)
*
|
2003-08-01 |
2006-06-22 |
제넨테크, 인크. |
제한된 다양성을 갖는 항체 cdr 폴리펩티드 서열
|
CA2535526C
(en)
|
2003-08-11 |
2015-09-29 |
Diversa Corporation |
Laccases, nucleic acids encoding them and methods for making and using them
|
EP1660534A2
(de)
*
|
2003-08-22 |
2006-05-31 |
MedImmune, Inc. |
Humanisierung von antikörpern
|
JP2005065575A
(ja)
*
|
2003-08-22 |
2005-03-17 |
Japan Science & Technology Agency |
フレームシャッフリングによるタンパク質分子多様性集団の作製
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
EP1689432B1
(de)
|
2003-11-17 |
2009-12-30 |
Genentech, Inc. |
Zusammensetzungen und verfahren zur behandlung von tumoren hämatopoetischen ursprungs
|
US20050112585A1
(en)
*
|
2003-11-21 |
2005-05-26 |
Dominic Zichi |
Method for adjusting the quantification range of individual analytes in a multiplexed assay
|
EP2221315A1
(de)
|
2003-12-04 |
2010-08-25 |
Xencor, Inc. |
Verfahren zur Erzeugung von Proteinvarianten mit erhöhtem Wirtsstranginhalt und Zusammensetzungen davon
|
WO2005062868A2
(en)
*
|
2003-12-19 |
2005-07-14 |
Osteotech, Inc. |
Tissue-derived mesh for orthopedic regeneration
|
EP3736335A1
(de)
|
2004-02-12 |
2020-11-11 |
Archemix LLC |
Aptamer-therapeutika zur behandlung komplementär hervorgerufener erkrankungen
|
US7803931B2
(en)
|
2004-02-12 |
2010-09-28 |
Archemix Corp. |
Aptamer therapeutics useful in the treatment of complement-related disorders
|
JP2007527246A
(ja)
*
|
2004-03-05 |
2007-09-27 |
アーケミックス コーポレイション |
ヒトil−12サイトカインファミリーに対するアプタマーおよび自己免疫疾患の治療剤としてのそれらの使用
|
US20060193821A1
(en)
*
|
2004-03-05 |
2006-08-31 |
Diener John L |
Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
|
US7569223B2
(en)
*
|
2004-03-22 |
2009-08-04 |
The Rockefeller University |
Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions
|
EP2053062A1
(de)
|
2004-03-24 |
2009-04-29 |
Xencor, Inc. |
Immunoglobinvarianten außerhalb der Fc-Region
|
US7785903B2
(en)
*
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
US20080214489A1
(en)
*
|
2004-04-19 |
2008-09-04 |
Anthony Dominic Keefe |
Aptamer-mediated intracellular delivery of oligonucleotides
|
AU2005238490B2
(en)
|
2004-04-22 |
2010-11-18 |
Tobira Therapeutics, Inc. |
Improved modulators of coagulation factors
|
US7579450B2
(en)
|
2004-04-26 |
2009-08-25 |
Archemix Corp. |
Nucleic acid ligands specific to immunoglobulin E and their use as atopic disease therapeutics
|
EP1745292A2
(de)
|
2004-04-28 |
2007-01-24 |
Bayer HealthCare AG |
Diagnositka und therapeutika für mit dipeptidyl-peptidase 1 (dpp1) assoziierten krankheiten
|
EP1789453A2
(de)
*
|
2004-05-18 |
2007-05-30 |
Genentech, Inc. |
Haupthüllproteinvarianten des m13-virus zur c-terminalen und bi-terminalen anzeige eines heterologen proteins
|
AU2005264938B2
(en)
|
2004-06-16 |
2011-11-24 |
Verenium Corporation |
Compositions and methods for enzymatic decolorization of chlorophyll
|
AU2005282380A1
(en)
*
|
2004-09-07 |
2006-03-16 |
Archemix Corp. |
Aptamer medicinal chemistry
|
KR20070101227A
(ko)
|
2004-09-07 |
2007-10-16 |
아케믹스 코포레이션 |
폰 빌레브란트 인자에 대한 앱타머 및 이의 혈전증치료제로서의 용도
|
US7566701B2
(en)
*
|
2004-09-07 |
2009-07-28 |
Archemix Corp. |
Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics
|
GB0422052D0
(en)
|
2004-10-04 |
2004-11-03 |
Dansico As |
Enzymes
|
GB0423139D0
(en)
|
2004-10-18 |
2004-11-17 |
Danisco |
Enzymes
|
CN102746404B
(zh)
|
2004-11-12 |
2016-01-20 |
赞科股份有限公司 |
对FcRn的结合被改变的Fc变体
|
ATE425186T1
(de)
|
2005-01-05 |
2009-03-15 |
F Star Biotech Forsch & Entw |
Synthetische immunoglobulindomänen mit in regionen des moleküls, die sich von den die komplementarität bestimmenden bereichen unterscheiden, modifizierten bindeeigenschaften
|
PA8660701A1
(es)
|
2005-02-04 |
2006-09-22 |
Pfizer Prod Inc |
Agonistas de pyy y sus usos
|
CA2596390A1
(en)
|
2005-02-08 |
2006-08-17 |
Zymogenetics, Inc. |
Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation
|
WO2006099207A2
(en)
|
2005-03-10 |
2006-09-21 |
Diversa Corporation |
Lyase enzymes, nucleic acids encoding them and methods for making and using them
|
CN101175769A
(zh)
|
2005-03-10 |
2008-05-07 |
健泰科生物技术公司 |
用于调控血管完整性的方法和组合物
|
NZ594810A
(en)
|
2005-03-15 |
2012-12-21 |
Verenium Corp |
Cellulases, nucleic acids encoding them and methods for making and using them
|
JO3058B1
(ar)
|
2005-04-29 |
2017-03-15 |
Applied Molecular Evolution Inc |
الاجسام المضادة لمضادات -اي ال-6,تركيباتها طرقها واستعمالاتها
|
WO2006124667A2
(en)
|
2005-05-12 |
2006-11-23 |
Zymogenetics, Inc. |
Compositions and methods for modulating immune responses
|
US20060271262A1
(en)
*
|
2005-05-24 |
2006-11-30 |
Mclain Harry P Iii |
Wireless agricultural network
|
US8389469B2
(en)
*
|
2005-06-06 |
2013-03-05 |
The Rockefeller University |
Bacteriophage lysins for Bacillus anthracis
|
US7582291B2
(en)
*
|
2005-06-30 |
2009-09-01 |
The Rockefeller University |
Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
|
JP2009501006A
(ja)
|
2005-06-30 |
2009-01-15 |
セントカー・インコーポレーテツド |
抗il−23抗体、組成物、方法および用途
|
US7700739B2
(en)
*
|
2005-06-30 |
2010-04-20 |
Abbott Laboratories |
IL-12/p40 binding proteins
|
US7612181B2
(en)
*
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
US20090215992A1
(en)
*
|
2005-08-19 |
2009-08-27 |
Chengbin Wu |
Dual variable domain immunoglobulin and uses thereof
|
RU2515108C2
(ru)
|
2005-08-19 |
2014-05-10 |
Эббви Инк |
Иммуноглобулин с двойными вариабельными доменами и его применения
|
EP2500356A3
(de)
|
2005-08-19 |
2012-10-24 |
Abbott Laboratories |
Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
|
CA2620903A1
(en)
|
2005-08-24 |
2007-03-01 |
The Rockefeller University |
Ply-gbs mutant lysins
|
WO2007035527A2
(en)
|
2005-09-15 |
2007-03-29 |
Duke University |
Non-fouling polymeric surface modification and signal amplification method for biomolecular detection
|
US8906864B2
(en)
*
|
2005-09-30 |
2014-12-09 |
AbbVie Deutschland GmbH & Co. KG |
Binding domains of proteins of the repulsive guidance molecule (RGM) protein family and functional fragments thereof, and their use
|
ES2577292T3
(es)
|
2005-11-07 |
2016-07-14 |
Genentech, Inc. |
Polipéptidos de unión con secuencias hipervariables de VH/VL diversificadas y consenso
|
GB2432366B
(en)
*
|
2005-11-19 |
2007-11-21 |
Alligator Bioscience Ab |
A method for in vitro molecular evolution of protein function
|
AU2006319358B2
(en)
*
|
2005-11-30 |
2012-01-19 |
AbbVie Deutschland GmbH & Co. KG |
Anti-Abeta globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies
|
KR101439828B1
(ko)
|
2005-11-30 |
2014-09-17 |
애브비 인코포레이티드 |
아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도
|
US20070237764A1
(en)
*
|
2005-12-02 |
2007-10-11 |
Genentech, Inc. |
Binding polypeptides with restricted diversity sequences
|
HUE034269T2
(en)
|
2005-12-29 |
2018-02-28 |
Janssen Biotech Inc |
Human anti-IL-23 antibodies, preparations, methods and applications
|
WO2007092314A2
(en)
|
2006-02-02 |
2007-08-16 |
Verenium Corporation |
Esterases and related nucleic acids and methods
|
WO2007092313A2
(en)
*
|
2006-02-03 |
2007-08-16 |
Indiana University Research And Technology Corporation |
Construction of open reading frame libraries and protein structures
|
DK2450439T3
(da)
|
2006-02-10 |
2014-02-10 |
Verenium Corp |
Cellulosenedbrydende enzymer, nucleinsyrer, der koder for dem, og fremgangsmåder til at fremstille og benytte dem
|
EP2548955A1
(de)
|
2006-02-14 |
2013-01-23 |
Verenium Corporation |
Xylanasen, Nukleinsäuren, die diese codieren, und Verfahren zu deren Herstellung und Verwendung
|
EP2112227B1
(de)
|
2006-03-07 |
2013-05-15 |
Cargill, Incorporated |
Aldolasen, Nukleinsäuren zu ihrer Kodierung sowie Verfahren zu ihrer Herstellung und Verwendung
|
KR101588539B1
(ko)
|
2006-03-07 |
2016-01-25 |
바스프 엔자임스 엘엘씨 |
알돌라제, 이것을 코딩하는 핵산과 그 제조 방법 및 사용 방법
|
PL2596807T3
(pl)
*
|
2006-03-08 |
2016-06-30 |
Archemix Llc |
Aptamery wiążące dopełniacza i środki anty-C5 użyteczne w leczeniu zaburzeń ocznych
|
EP2614839A3
(de)
|
2006-04-05 |
2015-01-28 |
Genentech, Inc. |
Verfahren zur Verwendung von BOC/CDO zur Modulation der Hedgehog-Signalisierung
|
CA2651567A1
(en)
*
|
2006-05-09 |
2007-11-22 |
Genentech, Inc. |
Binding polypeptides with optimized scaffolds
|
AT503902B1
(de)
*
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von immunglobulinen
|
AT503889B1
(de)
*
|
2006-07-05 |
2011-12-15 |
Star Biotechnologische Forschungs Und Entwicklungsges M B H F |
Multivalente immunglobuline
|
AT503861B1
(de)
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von t-zell-rezeptoren
|
CN101511868B
(zh)
|
2006-07-24 |
2013-03-06 |
比奥雷克西斯制药公司 |
毒蜥外泌肽融合蛋白
|
BRPI0714876B1
(pt)
|
2006-08-04 |
2022-04-19 |
Verenium Corporation |
Ácido nucleico isolado, sintético ou recombinante, cassete de expressão, vetor ou veículo de clonagem, célula bacteriana, fúngica ou de levedura transformada, polipeptídeo isolado, sintético ou recombinante, composição, bem como métodos de produção e de usos dos mesmos
|
US8586006B2
(en)
|
2006-08-09 |
2013-11-19 |
Institute For Systems Biology |
Organ-specific proteins and methods of their use
|
ES2902063T3
(es)
|
2006-09-08 |
2022-03-24 |
Abbvie Bahamas Ltd |
Proteínas de unión a interleucina-13
|
US20100297103A1
(en)
|
2006-09-14 |
2010-11-25 |
Medical & Biological Laboratories Co., Ltd. |
Antibody having enhanced adcc activity and method for production thereof
|
WO2008036863A2
(en)
|
2006-09-21 |
2008-03-27 |
Verenium Corporation |
Phospholipases, nucleic acids encoding them and methods for making and using them
|
CN113789316A
(zh)
|
2006-09-21 |
2021-12-14 |
巴斯夫酶有限责任公司 |
肌醇六磷酸酶、编码它们的核酸及制备和使用它们的方法
|
US9382327B2
(en)
|
2006-10-10 |
2016-07-05 |
Vaccinex, Inc. |
Anti-CD20 antibodies and methods of use
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
CA2673525C
(en)
|
2006-12-21 |
2017-12-05 |
Verenium Corporation |
Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them
|
US20110136099A1
(en)
|
2007-01-16 |
2011-06-09 |
Somalogic, Inc. |
Multiplexed Analyses of Test Samples
|
US8975026B2
(en)
|
2007-01-16 |
2015-03-10 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
US7964356B2
(en)
|
2007-01-16 |
2011-06-21 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
US7947447B2
(en)
|
2007-01-16 |
2011-05-24 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
US7855054B2
(en)
|
2007-01-16 |
2010-12-21 |
Somalogic, Inc. |
Multiplexed analyses of test samples
|
AU2008205457A1
(en)
*
|
2007-01-18 |
2008-07-24 |
University Of Southern California |
Gene polymorphisms predictive for dual TKI therapy
|
CA2674721C
(en)
|
2007-01-30 |
2018-04-03 |
Verenium Corporation |
Enzymes for the treatment of lignocellulosics, nucleic acids encoding them and methods for making and using them
|
US8143046B2
(en)
|
2007-02-07 |
2012-03-27 |
Danisco Us Inc., Genencor Division |
Variant Buttiauxella sp. phytases having altered properties
|
EP2126105A4
(de)
*
|
2007-02-20 |
2010-11-03 |
Anaptysbio Inc |
Somatische hyperpermutationssysteme
|
US7875431B2
(en)
|
2007-02-22 |
2011-01-25 |
Genentech, Inc. |
Methods for detecting inflammatory bowel disease
|
WO2008104386A2
(en)
*
|
2007-02-27 |
2008-09-04 |
Abbott Gmbh & Co. Kg |
Method for the treatment of amyloidoses
|
US20090232801A1
(en)
*
|
2007-05-30 |
2009-09-17 |
Abbot Laboratories |
Humanized Antibodies Which Bind To AB (1-42) Globulomer And Uses Thereof
|
PE20090329A1
(es)
*
|
2007-05-30 |
2009-03-27 |
Abbott Lab |
Anticuerpos humanizados contra el globulomero ab(20-42) y sus usos
|
US20090203766A1
(en)
*
|
2007-06-01 |
2009-08-13 |
Archemix Corp. |
vWF aptamer formulations and methods for use
|
JP5602625B2
(ja)
|
2007-06-26 |
2014-10-08 |
エフ−スター ビオテヒノロギッシェ フォルシュングス− ウント エントヴィッケルングスゲゼルシャフト ミット ベシュレンクテル ハフツング |
結合物質のディスプレイ
|
JP5684568B2
(ja)
|
2007-07-17 |
2015-03-11 |
ソマロジック・インコーポレーテッド |
改善されたオフ速度(off−rate)を持つアプタマーを生成するための方法
|
EP2033971A1
(de)
*
|
2007-09-06 |
2009-03-11 |
Abbott GmbH & Co. KG |
Bone Morphogenetic Protein (BMP)-bindende Domänen von Proteinen der Repulsive Guidance Molecule (RGM) Proteinfamilie und funktionale Fragmente davon sowie deren Verwendung
|
EP2193146B1
(de)
*
|
2007-09-14 |
2016-05-25 |
Adimab, LLC |
Synthetische antikörperbibliotheken mit rationalem design und ihre verwendung
|
US8877688B2
(en)
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
EP2915564B1
(de)
|
2007-09-28 |
2020-11-04 |
Portola Pharmaceuticals, Inc. |
Gegenmittel für Faktor-XA-Hemmer und Verfahren zur Verwendung davon
|
WO2009045627A2
(en)
|
2007-10-03 |
2009-04-09 |
Verenium Corporation |
Xylanases, nucleic acids encoding them and methods for making and using them
|
JP2011502964A
(ja)
|
2007-10-23 |
2011-01-27 |
ザ レジェンツ オブ ザ ユニバーシティ オブ コロラド |
インバリアント鎖発現および/または異所性clip結合の競合的阻害剤
|
WO2009055656A2
(en)
|
2007-10-26 |
2009-04-30 |
Centocor, Inc. |
Vectors, host cells, and methods of production and uses
|
US8906700B2
(en)
|
2007-11-06 |
2014-12-09 |
Ambergen, Inc. |
Methods and compositions for phototransfer
|
US20110039722A1
(en)
*
|
2007-12-31 |
2011-02-17 |
Xoma Technology Ltd. |
Libraries, arrays and their uses for targeted affinity enhancement
|
US8541220B2
(en)
|
2008-01-03 |
2013-09-24 |
Verenium Corporation |
Isomerases, nucleic acids encoding them and methods for making and using them
|
JP5563990B2
(ja)
|
2008-01-03 |
2014-07-30 |
ヴェレニウム コーポレイション |
トランスフェラーゼおよびオキシドレダクターゼ、それらをコードする核酸並びにそれらを製造および使用する方法
|
US7682809B2
(en)
|
2008-01-11 |
2010-03-23 |
Agilent Technologies, Inc. |
Direct ATP release sequencing
|
US8962803B2
(en)
*
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
US9873957B2
(en)
*
|
2008-03-13 |
2018-01-23 |
Dyax Corp. |
Libraries of genetic packages comprising novel HC CDR3 designs
|
EP2281078B1
(de)
|
2008-04-24 |
2014-10-22 |
Dyax Corporation |
Bibliotheken von genetischen packungen, umfassend neue hc-cdr1, -cdr2, und -cdr3, und neue lc-cdr1-, -cdr2- und -cdr3-designs
|
SG190572A1
(en)
|
2008-04-29 |
2013-06-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
US20100260668A1
(en)
*
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
WO2009133464A2
(en)
|
2008-04-30 |
2009-11-05 |
Danisco A/S |
Oxidation process
|
EP2113255A1
(de)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Zytotoxisches Immunglobulin
|
MY159667A
(en)
|
2008-05-09 |
2017-01-13 |
Abbvie Inc |
Antibodies to receptor of advanced glycation end products (rage) and uses thereof
|
RU2010153578A
(ru)
|
2008-06-03 |
2012-07-20 |
Эбботт Лэборетриз (Us) |
Иммуноглобулины с двойными вариабельными доменами и их применение
|
CA2726087A1
(en)
*
|
2008-06-03 |
2009-12-10 |
Tariq Ghayur |
Dual variable domain immunoglobulins and uses thereof
|
MX2010014358A
(es)
|
2008-06-20 |
2011-07-04 |
Wyeth Llc |
Composiciones y metodos de uso del orf1358 de cepas estreptococicas beta-hemoliticas.
|
EP2319869B1
(de)
|
2008-06-20 |
2016-08-17 |
National University Corporation Okayama University |
ANTIKÖRPER GEGEN DEN OXIDIERTES LDL/ß²GPI-KOMPLEX UND ANWENDUNG DAVON
|
RU2011104348A
(ru)
*
|
2008-07-08 |
2012-08-20 |
Эбботт Лэборетриз (Us) |
Иммуноглобулины с двойным вариабельным доменом против простагландина е2 и их применение
|
TW201014602A
(en)
|
2008-07-08 |
2010-04-16 |
Abbott Lab |
Prostaglandin E2 binding proteins and uses thereof
|
US8703416B2
(en)
|
2008-07-17 |
2014-04-22 |
Somalogic, Inc. |
Method for purification and identification of sperm cells
|
US20100166782A1
(en)
*
|
2008-07-25 |
2010-07-01 |
Martha Karen Newell |
Clip inhibitors and methods of modulating immune function
|
AU2009274568A1
(en)
*
|
2008-07-25 |
2010-01-28 |
The Regents Of The University Of Colorado |
Proteins for use in diagnosing and treating infection and disease
|
US9182406B2
(en)
*
|
2008-08-04 |
2015-11-10 |
Biodesy, Inc. |
Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
|
US8563697B2
(en)
|
2008-08-14 |
2013-10-22 |
Cephalon Australia Pty. Ltd. |
Anti-IL-12/IL-23 antibodies
|
US8198062B2
(en)
|
2008-08-29 |
2012-06-12 |
Dsm Ip Assets B.V. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
US8153391B2
(en)
|
2008-08-29 |
2012-04-10 |
Bunge Oils, Inc. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
US8357503B2
(en)
|
2008-08-29 |
2013-01-22 |
Bunge Oils, Inc. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
AU2009307249B2
(en)
|
2008-10-20 |
2012-11-01 |
Gwangju Institute Of Science And Technology |
Bipodal peptide binder
|
BRPI0922807A2
(pt)
*
|
2008-12-04 |
2015-12-22 |
Abbott Lab |
imonuglobulinas de domínio variável duplo e usos dos mesmos
|
EP2379720B1
(de)
|
2009-01-20 |
2016-08-17 |
Alona Zilberberg |
Durch den promoter mir-21 angetriebene gezielte krebstherapie
|
US20110165063A1
(en)
*
|
2009-01-29 |
2011-07-07 |
Abbott Laboratories |
Il-1 binding proteins
|
KR20110110349A
(ko)
*
|
2009-01-29 |
2011-10-06 |
아보트 러보러터리즈 |
Il-1 결합 단백질
|
US8030026B2
(en)
*
|
2009-02-24 |
2011-10-04 |
Abbott Laboratories |
Antibodies to troponin I and methods of use thereof
|
EP2810652A3
(de)
|
2009-03-05 |
2015-03-11 |
AbbVie Inc. |
IL-17-bindende Proteine
|
EP3121271B1
(de)
|
2009-03-30 |
2019-07-24 |
Portola Pharmaceuticals, Inc. |
Gegenmittel für faktor-xa-hemmer und verfahren zur verwendung davon
|
GB0908770D0
(en)
|
2009-04-24 |
2009-07-01 |
Danisco |
Method
|
CN102459303B
(zh)
|
2009-05-21 |
2016-06-29 |
巴斯夫酶有限责任公司 |
肌醇六磷酸酶、编码它们的核酸及制备和使用它们的方法
|
WO2011008885A1
(en)
|
2009-07-15 |
2011-01-20 |
Portola Pharmaceuticals, Inc. |
Unit dose formulation of antidotes for factor xa inhibitors and methods of using the same
|
UY32808A
(es)
*
|
2009-07-29 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas como dominio variable dual y usos de las mismas
|
EP3029070A1
(de)
|
2009-08-29 |
2016-06-08 |
AbbVie Inc. |
Therapeutische dll4-bindende proteine
|
KR20120060877A
(ko)
|
2009-09-01 |
2012-06-12 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
JP2013504602A
(ja)
*
|
2009-09-14 |
2013-02-07 |
ダイアックス コーポレーション |
新しく設計したhccdr3を含む遺伝子パッケージライブラリー
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
US9885711B2
(en)
|
2009-09-25 |
2018-02-06 |
Xoma Technology Ltd. |
Screening methods
|
AU2010306677B2
(en)
|
2009-10-15 |
2013-05-23 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
UA109884C2
(uk)
|
2009-10-16 |
2015-10-26 |
|
Поліпептид, що має активність ферменту фосфатидилінозитол-специфічної фосфоліпази с, нуклеїнова кислота, що його кодує, та спосіб його виробництва і застосування
|
UA111708C2
(uk)
|
2009-10-16 |
2016-06-10 |
Бандж Ойлз, Інк. |
Спосіб рафінування олії
|
BR112012009409A2
(pt)
|
2009-10-22 |
2017-02-21 |
Genentech Inc |
método de identificação de uma substância inibidora, molécula antagonista, ácido nucleico isolado, vetor, célula hospedeira, método para fabricar a molécula, composição, artigo de fabricação, método de inibição de uma atividade biológica, método de tratamento de uma condição patológica, método para detectar msp em uma amostra e método para detectar hepsina em uma amostra
|
UY32979A
(es)
*
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
WO2011053707A1
(en)
|
2009-10-31 |
2011-05-05 |
Abbott Laboratories |
Antibodies to receptor for advanced glycation end products (rage) and uses thereof
|
AR079217A1
(es)
|
2009-11-30 |
2012-01-04 |
Genentech Inc |
Composiciones y metodos para el diagnostico y el tratamiento de tumores
|
SG181563A1
(en)
*
|
2009-12-08 |
2012-07-30 |
Abbott Gmbh & Co Kg |
Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
|
CN102933231B
(zh)
|
2010-02-10 |
2015-07-29 |
伊缪诺金公司 |
Cd20抗体及其用途
|
JP5981853B2
(ja)
|
2010-02-18 |
2016-08-31 |
ジェネンテック, インコーポレイテッド |
ニューレグリンアンタゴニスト及び癌の治療におけるそれらの使用
|
MX2012009215A
(es)
|
2010-02-23 |
2012-11-23 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento de tumores.
|
TW202348631A
(zh)
|
2010-02-24 |
2023-12-16 |
美商免疫遺傳股份有限公司 |
葉酸受體1抗體類和免疫共軛物類及彼等之用途
|
EP2542582A4
(de)
|
2010-03-02 |
2013-12-04 |
Abbvie Inc |
Therapeutische dll4-bindende proteine
|
AU2011223527B2
(en)
|
2010-03-03 |
2014-11-13 |
Somalogic Operating Co., Inc. |
Aptamers to 4-1BB and their use in treating diseases and disorders
|
SI2552961T1
(en)
|
2010-03-30 |
2018-02-28 |
Janssen Biotech, Inc. |
Humanized antibodies against IL-25
|
SG184497A1
(en)
|
2010-04-12 |
2012-11-29 |
Somalogic Inc |
5-position modified pyrimidines and their use
|
CA2796339C
(en)
|
2010-04-15 |
2020-03-31 |
Abbott Laboratories |
Amyloid-beta binding proteins
|
MA34291B1
(fr)
|
2010-05-03 |
2013-06-01 |
Genentech Inc |
Compositions et méthodes de diagnostic et de traitement d'une tumeur
|
SI2571532T1
(sl)
|
2010-05-14 |
2017-10-30 |
Abbvie Inc. |
Proteini, ki vežejo IL-1
|
GB201011513D0
(en)
|
2010-07-08 |
2010-08-25 |
Danisco |
Method
|
WO2012006500A2
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
EP4219805A1
(de)
|
2010-07-16 |
2023-08-02 |
Adimab, LLC |
Antikörperbibliotheken
|
KR20130100118A
(ko)
|
2010-08-03 |
2013-09-09 |
아비에 인코포레이티드 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
EP3533803B1
(de)
|
2010-08-14 |
2021-10-27 |
AbbVie Inc. |
Anti-amyloid-beta antikörper
|
HUE058226T2
(hu)
|
2010-08-19 |
2022-07-28 |
Zoetis Belgium S A |
NGF elleni antitestek és alkalmazásuk
|
CA2809433A1
(en)
|
2010-08-26 |
2012-03-01 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
BR112013008347A2
(pt)
|
2010-10-06 |
2016-06-14 |
Bp Corp North America Inc |
polipeptídeos de variantes cbh i
|
US20120275996A1
(en)
|
2010-12-21 |
2012-11-01 |
Abbott Laboratories |
IL-1 Binding Proteins
|
KR20130133247A
(ko)
|
2010-12-21 |
2013-12-06 |
애브비 인코포레이티드 |
Il-1-알파 및 -베타 이특이적 이원 가변 도메인 면역글로불린 및 이의 용도
|
MX344595B
(es)
|
2010-12-31 |
2016-12-20 |
Bioatla Llc |
Humanizacion rapida de anticuerpos.
|
WO2012129347A1
(en)
|
2011-03-21 |
2012-09-27 |
Biodesy, Llc |
Classification of kinase inhibitors using nonlinear optical techniques
|
CN108578685A
(zh)
|
2011-04-21 |
2018-09-28 |
洛克菲勒大学 |
用于革兰氏阳性菌检测和治疗的链球菌属细菌噬菌体溶素
|
EP2734236A4
(de)
|
2011-07-13 |
2015-04-15 |
Abbvie Inc |
Verfahren und zusammensetzungen zur behandlung von asthma mit anti-il-13-antikörpern
|
US8609355B2
(en)
|
2011-07-26 |
2013-12-17 |
Indicator Systems International, Inc. |
Assays for the detection of microbes
|
KR20140068062A
(ko)
|
2011-09-15 |
2014-06-05 |
제넨테크, 인크. |
분화의 촉진 방법
|
DK2764093T3
(en)
|
2011-10-05 |
2018-07-30 |
Univ Rockefeller |
DIMER BACTERYPHAGE LYSINES
|
KR20140084164A
(ko)
|
2011-10-15 |
2014-07-04 |
제넨테크, 인크. |
암의 치료를 위한 scd1 길항제
|
MX2014004977A
(es)
|
2011-10-24 |
2014-09-11 |
Abbvie Inc |
Inmunoaglutinantes dirigidos contra esclerostina.
|
US9220775B2
(en)
|
2011-11-23 |
2015-12-29 |
Medimmune Llc |
Binding molecules specific for HER3 and uses thereof
|
US10118958B2
(en)
|
2011-12-14 |
2018-11-06 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
CA2855570A1
(en)
|
2011-12-14 |
2013-06-20 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
TW201333035A
(zh)
|
2011-12-30 |
2013-08-16 |
Abbvie Inc |
針對il-13及/或il-17之雙特異性結合蛋白
|
CN104168920A
(zh)
|
2012-01-18 |
2014-11-26 |
霍夫曼-拉罗奇有限公司 |
使用fgf19调控剂的方法
|
EP2804878B1
(de)
|
2012-01-20 |
2018-08-22 |
Genzyme Corporation |
Anti-cxcr3-antikörper
|
MY176695A
(en)
|
2012-01-27 |
2020-08-19 |
Abbvie Inc |
Composition and method for the diagnosis and treatment of diseases associated with neurite degeneration
|
BR112014019741A2
(pt)
|
2012-02-11 |
2020-12-22 |
Genentech, Inc |
Usos de um antagonista da via wnt, uso de uma terapia anticâncer, método de identificação de um indivíduo com câncer, métodos para prever, método de inibição da proliferação de uma célula de câncer, uso de um antagonista da translocação de r-spondina e antagonista da translocação de r-spondina isolado
|
EP3296320A1
(de)
|
2012-03-08 |
2018-03-21 |
Halozyme, Inc. |
Bedingt aktive antikörper gegen den epidermalen wachstumsfaktorrezeptor und verfahren zur verwendung davon
|
MX2014010953A
(es)
|
2012-03-16 |
2014-10-13 |
Hoffmann La Roche |
Metodos para tratamiento de melanoma con inhibidores pak1.
|
JP6200437B2
(ja)
|
2012-03-16 |
2017-09-20 |
ユニバーシティ ヘルス ネットワーク |
Toso活性を調節するための方法および組成物
|
US9139863B2
(en)
|
2012-03-16 |
2015-09-22 |
Genentech, Inc. |
Engineered conformationally-stabilized proteins
|
KR20140142293A
(ko)
|
2012-03-16 |
2014-12-11 |
제넨테크, 인크. |
조작된 입체형태적으로-안정화된 단백질
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
CN106290917B
(zh)
|
2012-04-25 |
2020-06-05 |
比奥德赛公司 |
用于检测蛋白质的变构调节剂的方法
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
CN104603149B
(zh)
|
2012-05-24 |
2017-06-30 |
万机集团有限公司 |
与预防和治疗狂犬病感染相关的组合物和方法
|
EP2859018B1
(de)
|
2012-06-06 |
2021-09-22 |
Zoetis Services LLC |
Anti-ngf-antikörper für hunde und verfahren dafür
|
WO2014011955A2
(en)
|
2012-07-12 |
2014-01-16 |
Abbvie, Inc. |
Il-1 binding proteins
|
NZ726258A
(en)
|
2012-08-31 |
2019-07-26 |
Immunogen Inc |
Antibodies and uses thereof to detect folate receptor 1
|
CA2890263C
(en)
|
2012-11-01 |
2020-03-10 |
Abbvie Inc. |
Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof
|
US9550986B2
(en)
|
2012-12-21 |
2017-01-24 |
Abbvie Inc. |
High-throughput antibody humanization
|
JP2016509045A
(ja)
|
2013-02-22 |
2016-03-24 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
がんを治療し、薬剤耐性を防止する方法
|
US9925240B2
(en)
|
2013-03-06 |
2018-03-27 |
Genentech, Inc. |
Methods of treating and preventing cancer drug resistance
|
GB201308828D0
(en)
|
2013-03-12 |
2013-07-03 |
Verenium Corp |
Phytase
|
JP2016512241A
(ja)
|
2013-03-14 |
2016-04-25 |
アボット・ラボラトリーズAbbott Laboratories |
改良された抗体検出のためのhcvns3組換え抗原およびこの突然変異体
|
JP6739329B2
(ja)
|
2013-03-14 |
2020-08-12 |
アボット・ラボラトリーズAbbott Laboratories |
Hcvコア脂質結合ドメインモノクローナル抗体
|
EP2968526A4
(de)
|
2013-03-14 |
2016-11-09 |
Abbott Lab |
Hcv-antigen-antikörper-kombinationstest sowie verfahren und zusammensetzungen zur verwendung darin
|
CA2905070A1
(en)
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
GB201308843D0
(en)
|
2013-03-14 |
2013-07-03 |
Verenium Corp |
Phytase formulation
|
WO2014144280A2
(en)
|
2013-03-15 |
2014-09-18 |
Abbvie Inc. |
DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST IL-1β AND / OR IL-17
|
MX360160B
(es)
|
2013-03-15 |
2018-10-24 |
Pioneer Hi Bred Int |
Polipeptidos phi-4 y metodos para su uso.
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
MX2015011899A
(es)
|
2013-03-15 |
2016-05-05 |
Genentech Inc |
Metodos para el tratamiento de cáncer y prevención de resistencia a los fármacos para el cáncer.
|
EP2972373B1
(de)
|
2013-03-15 |
2019-10-09 |
F.Hoffmann-La Roche Ag |
Biomarker und verfahren zur behandlung von pd-1 und pd-l1-verwandten leiden
|
ES2753419T3
(es)
|
2013-06-07 |
2020-04-08 |
Univ Duke |
Inhibidores del factor H del complemento
|
JP2016525354A
(ja)
|
2013-07-25 |
2016-08-25 |
ビーエーエスエフ エンザイムズ エルエルシー |
フィターゼ
|
CA2920339C
(en)
|
2013-08-16 |
2023-10-24 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
KR102585409B1
(ko)
|
2013-08-30 |
2023-10-05 |
이뮤노젠 아이엔씨 |
엽산 수용체 1의 검출을 위한 항체 및 분석
|
MX2016003256A
(es)
|
2013-09-12 |
2016-06-07 |
Halozyme Inc |
Anticuerpos modificados del receptor de factor de crecimiento anti-epidermico y metodos de uso de los mismos.
|
ES2776730T3
(es)
|
2013-09-13 |
2020-07-31 |
Pioneer Hi Bred Int |
Proteínas insecticidas y métodos para su uso
|
PL3712174T3
(pl)
|
2013-12-24 |
2022-07-04 |
Janssen Pharmaceutica Nv |
Przeciwciała i fragmenty anty-vista
|
WO2015116902A1
(en)
|
2014-01-31 |
2015-08-06 |
Genentech, Inc. |
G-protein coupled receptors in hedgehog signaling
|
CN106232620B
(zh)
|
2014-02-07 |
2022-05-13 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
RU2021113662A
(ru)
|
2014-02-07 |
2021-05-31 |
Пайонир Хай-Бред Интернэшнл, Инк. |
Инсектицидные белки и способы их применения
|
AU2015225867B2
(en)
|
2014-03-07 |
2020-02-06 |
University Health Network |
Methods and compositions for modifying the immune response
|
KR102546611B1
(ko)
|
2014-04-08 |
2023-06-22 |
보스턴 파마슈티칼즈, 아이엔씨. |
Il-21에 특이적인 결합 분자 및 이들 용도
|
US10160812B2
(en)
|
2014-04-11 |
2018-12-25 |
Medimmune, Llc |
Bispecific HER2 antibodies
|
GB201406767D0
(en)
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
CA3225091A1
(en)
|
2014-05-05 |
2015-11-12 |
Regeneron Pharmaceuticals, Inc. |
Humanized c5 and c3 animals
|
CN106661622B
(zh)
|
2014-05-23 |
2020-08-21 |
豪夫迈·罗氏有限公司 |
Mit生物标志物和使用它们的方法
|
JP2017517552A
(ja)
|
2014-06-13 |
2017-06-29 |
ジェネンテック, インコーポレイテッド |
抗癌剤耐性の治療及び防止方法
|
US10562946B2
(en)
|
2014-06-20 |
2020-02-18 |
Genentech, Inc. |
Chagasin-based scaffold compositions, methods, and uses
|
EP3207143B1
(de)
|
2014-10-16 |
2023-11-22 |
Pioneer Hi-Bred International, Inc. |
Insektizide proteine und verfahren zu deren verwendung
|
EP3209774B1
(de)
|
2014-10-24 |
2020-02-26 |
DuPont Nutrition Biosciences ApS |
Verwendung von prolintoleranten tripeptidylpeptidasen in futterzusatzzusammensetzungen
|
US20170306360A1
(en)
|
2014-10-24 |
2017-10-26 |
Danisco Us Inc. |
Method for producing alcohol by use of a tripeptidyl peptidase
|
AU2015345202B2
(en)
|
2014-11-10 |
2021-05-13 |
Medimmune Limited |
Binding molecules specific for CD73 and uses thereof
|
JP6847037B2
(ja)
|
2014-11-11 |
2021-03-24 |
メディミューン リミテッド |
抗cd73抗体とa2a受容体阻害薬とを含む併用治療薬及びその使用
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
EP3237906B8
(de)
|
2014-12-23 |
2020-10-28 |
Bluelight Therapeutics, Inc. |
Befestigung von proteinen an schnittstellen zur verwendung in nicht-linearer optischer detektion
|
CA2973978A1
(en)
|
2015-01-14 |
2016-07-21 |
The Brigham And Women's Hospital, Inc. |
Treatment of cancer with anti-lap monoclonal antibodies
|
MX2017011525A
(es)
|
2015-03-11 |
2018-01-30 |
Pioneer Hi Bred Int |
Combinaciones insecticidas de pip-72 y metodos de uso.
|
CN107787332B
(zh)
|
2015-04-24 |
2022-09-09 |
豪夫迈·罗氏有限公司 |
多特异性抗原结合蛋白
|
BR112017024948A2
(pt)
|
2015-05-19 |
2018-07-31 |
Pioneer Hi Bred Int |
proteínas inseticidas e métodos para uso das mesmas
|
HUE048284T2
(hu)
|
2015-05-29 |
2020-07-28 |
Abbvie Inc |
Anti-CD40 antitestek és alkalmazásuk
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
JP7026509B2
(ja)
|
2015-06-24 |
2022-02-28 |
ヤンセン ファーマシューティカ エヌブイ |
抗vista抗体およびフラグメント
|
MX2017016501A
(es)
|
2015-06-26 |
2018-03-12 |
Dupont Nutrition Biosci Aps |
Aminopeptidasas para hidrolizados de proteinas.
|
HUE053619T2
(hu)
|
2015-06-29 |
2021-07-28 |
Immunogen Inc |
Anti-CD123 antitestek és konjugátumok és ezek származékai
|
US10287338B2
(en)
|
2015-07-10 |
2019-05-14 |
Miran NERSISSIAN |
Factor VIII protein compositions and methods of treating of hemophilia A
|
WO2017023863A1
(en)
|
2015-07-31 |
2017-02-09 |
Research Institute At Nationwide Children's Hospital |
Peptides and antibodies for the removal of biofilms
|
US11198709B2
(en)
|
2015-08-06 |
2021-12-14 |
E. I. Du Pont De Nemours And Company |
Plant derived insecticidal proteins and methods for their use
|
WO2017066719A2
(en)
|
2015-10-14 |
2017-04-20 |
Research Institute At Nationwide Children's Hospital |
Hu specific interfering agents
|
RU2710194C9
(ru)
|
2015-11-10 |
2020-09-14 |
МЕДИММЬЮН, ЭлЭлСи |
Связывающие молекулы, специфичные в отношении asct2, и их применения
|
CN108575091A
(zh)
|
2015-12-18 |
2018-09-25 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
EP3405478A4
(de)
|
2015-12-23 |
2019-10-30 |
Moonshot Pharma LLC |
Verfahren zur induzierung einer immunantwort durch hemmung von nonsense-vermitteltem zerfall
|
CN116920085A
(zh)
|
2016-02-12 |
2023-10-24 |
詹森药业有限公司 |
抗-vista(b7h5)抗体
|
WO2017147060A1
(en)
|
2016-02-25 |
2017-08-31 |
Dupont Nutrition Biosciences Aps |
Method for producing a protein hydrolysate employing an aspergillus fumigatus tripeptidyl peptidase
|
WO2017156488A2
(en)
|
2016-03-10 |
2017-09-14 |
Acceleron Pharma, Inc. |
Activin type 2 receptor binding proteins and uses thereof
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
AU2017241776A1
(en)
|
2016-03-29 |
2018-10-11 |
Janssen Biotech, Inc. |
Treating psoriasis with increased interval dosing of anti-IL12 and/or -23 antibody
|
WO2017175058A1
(en)
|
2016-04-07 |
2017-10-12 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
EP3448391A4
(de)
|
2016-04-27 |
2019-12-18 |
AbbVie Inc. |
Verfahren zur behandlung von erkrankungen mit schädlicher il-13 aktivität unter verwendung von anti-il-13-antikörpern
|
CA3018384A1
(en)
|
2016-05-04 |
2017-11-09 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
MY194619A
(en)
|
2016-06-02 |
2022-12-07 |
Abbvie Inc |
Glucocorticoid receptor agonist and immunoconjugates thereof
|
CA3027103A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
WO2017214335A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
CN109563167A
(zh)
|
2016-06-08 |
2019-04-02 |
艾伯维公司 |
抗b7-h3抗体和抗体药物偶联物
|
GB201610198D0
(en)
|
2016-06-10 |
2016-07-27 |
Ucb Biopharma Sprl |
Anti-ige antibodies
|
EP3472186A1
(de)
|
2016-06-17 |
2019-04-24 |
National Hellenic Research Foundation |
Systeme zur rekombinanten proteinproduktion
|
WO2018005411A1
(en)
|
2016-07-01 |
2018-01-04 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins from plants and methods for their use
|
JP2019534858A
(ja)
|
2016-09-09 |
2019-12-05 |
ジェネンテック, インコーポレイテッド |
Frizzledの選択的ペプチド阻害剤
|
MX2019003703A
(es)
|
2016-09-30 |
2020-08-13 |
Janssen Biotech Inc |
Método seguro y eficaz para tratar la psoriasis con el anticuerpo específico anti-il23.
|
EP3519824A1
(de)
|
2016-10-03 |
2019-08-07 |
Abbott Laboratories |
Verbesserte verfahren zur beurteilung des uch-l1-status in patientenproben
|
WO2018084936A1
(en)
|
2016-11-01 |
2018-05-11 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
AU2017362222A1
(en)
|
2016-11-16 |
2019-05-30 |
Janssen Biotech, Inc. |
Method of treating psoriasis with anti-IL-23 specific antibody
|
JP7227146B2
(ja)
|
2016-11-23 |
2023-02-21 |
バイオベラティブ セラピューティクス インコーポレイテッド |
凝固第ix因子および凝固第x因子に結合する二重特異性抗体
|
WO2018098370A1
(en)
|
2016-11-23 |
2018-05-31 |
Immunoah Therapeutics, Inc. |
4-1bb binding proteins and uses thereof
|
CN110088123B
(zh)
|
2016-12-14 |
2023-10-20 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
WO2018118811A1
(en)
|
2016-12-22 |
2018-06-28 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
CA3049105A1
(en)
|
2017-01-04 |
2018-07-12 |
Lauren O. Bakaletz |
Dnabii vaccines and antibodies with enhanced activity
|
CA3049114A1
(en)
|
2017-01-04 |
2018-07-12 |
Lauren O. Bakaletz |
Antibody fragments for the treatment of biofilm-related disorders
|
TW201825515A
(zh)
|
2017-01-04 |
2018-07-16 |
美商伊繆諾金公司 |
Met抗體以及其免疫結合物及用途
|
EP3565845A4
(de)
|
2017-01-06 |
2020-10-07 |
Biosion, Inc. |
Erbb2-antikörper und deren verwendungen
|
CA3052095A1
(en)
|
2017-01-30 |
2018-08-02 |
Janssen Biotech, Inc. |
Anti-tnf antibodies, compositions, and methods for the treatment of active psoriatic arthritis
|
MA47442A
(fr)
|
2017-02-07 |
2019-12-18 |
Janssen Biotech Inc |
Anticorps anti-tnf, compositions et méthodes pour le traitement de la spondylarthrite ankylosante active
|
BR112019016394A2
(pt)
|
2017-02-08 |
2020-04-07 |
Pioneer Hi Bred Int |
construto de dna, pilha molecular, pilha de melhoramento, planta transgênica ou progênie da mesma, composição e método para controlar uma população de praga de inseto
|
WO2018152496A1
(en)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions and methods for the diagnosis and treatment of zika virus infection
|
AU2018225745B2
(en)
|
2017-02-27 |
2023-12-07 |
Regeneron Pharmaceuticals, Inc. |
Humanized model of kidney and liver disorders
|
CA3056088A1
(en)
|
2017-03-15 |
2018-09-20 |
Research Institute At Nationwide Children's Hospital |
Composition and methods for disruption of bacterial biofilms without accompanying inflammation
|
US11016092B2
(en)
|
2017-03-23 |
2021-05-25 |
Abbott Laboratories |
Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase L1
|
US10877048B2
(en)
|
2017-04-15 |
2020-12-29 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers
|
JP7248588B2
(ja)
|
2017-04-21 |
2023-03-29 |
ジェネンテック, インコーポレイテッド |
疾患の治療のためのklk5アンタゴニストの使用
|
EP3615569A1
(de)
|
2017-04-25 |
2020-03-04 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Antikörper und verfahren zur diagnose und behandlung von epstein-barr-virus-infektionen
|
US10877038B2
(en)
|
2017-04-28 |
2020-12-29 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
BR112019023628A2
(pt)
|
2017-05-11 |
2020-06-02 |
Pioneer Hi-Bred International, Inc. |
Polipeptídeo inseticida recombinante, proteína inseticida quimérica, proteína de fusão, composição agrícola, polinucleotídeo recombinante, construto de dna, planta transgênica, método para inibir o crescimento ou exterminar uma praga de inseto ou população de praga, método para controlar os danos por praga de inseto, método para controlar infestação de praga e método para melhorar o rendimento de uma cultura
|
AU2018272054A1
(en)
|
2017-05-25 |
2019-09-26 |
Abbott Laboratories |
Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
|
JP7269183B2
(ja)
|
2017-05-30 |
2023-05-08 |
アボット・ラボラトリーズ |
心臓トロポニンiを使用する、ヒト対象における軽度外傷性脳損傷を診断及び査定する一助となるための方法
|
JP2020525434A
(ja)
|
2017-06-22 |
2020-08-27 |
ムーンショット ファーマ エルエルシー |
アンレキサノクス及び免疫調節剤を含む組成物で癌を治療する方法
|
WO2019010131A1
(en)
|
2017-07-03 |
2019-01-10 |
Abbott Laboratories |
IMPROVED METHODS FOR MEASURING CARBOXY TERMINATION HYDROLASE LEVELS OF UBIQUITIN L1 IN BLOOD
|
CN111094334A
(zh)
|
2017-07-19 |
2020-05-01 |
美国卫生与公众服务部 |
用于诊断和治疗乙肝病毒感染的抗体和方法
|
JP6889328B2
(ja)
|
2017-07-31 |
2021-06-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
三次元構造に基づくヒト化方法
|
TW201922780A
(zh)
|
2017-09-25 |
2019-06-16 |
美商健生生物科技公司 |
以抗il12/il23抗體治療狼瘡之安全且有效之方法
|
CA3078460A1
(en)
|
2017-10-04 |
2019-04-11 |
Opko Pharmaceuticals, Llc |
Articles and methods directed to personalized therapy of cancer
|
WO2019075090A1
(en)
|
2017-10-10 |
2019-04-18 |
Tilos Therapeutics, Inc. |
ANTI-LAP ANTIBODIES AND USES THEREOF
|
WO2019094595A2
(en)
|
2017-11-09 |
2019-05-16 |
Pinteon Therapeutics Inc. |
Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies
|
US11022617B2
(en)
|
2017-12-09 |
2021-06-01 |
Abbott Laboratories |
Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (TBI), using glial fibrillary acidic protein (GFAP) and/or ubiquitin carboxy-terminal hydrolase L1 (UCH-L1)
|
BR112020010085A2
(pt)
|
2017-12-09 |
2020-10-13 |
Abbott Laboratories |
métodos para auxiliar no diagnóstico e avaliar uma lesão cerebral traumática em um indivíduo humano usando uma combinação de gfap e uch-l1
|
EP3728321A1
(de)
|
2017-12-22 |
2020-10-28 |
F. Hoffmann-La Roche AG |
Verwendung von pilra-bindenden mitteln zur behandlung einer erkrankung
|
JP7437303B2
(ja)
|
2017-12-29 |
2024-02-22 |
アボット・ラボラトリーズ |
外傷性脳損傷を診断及び査定するための、新規のバイオマーカー及び方法
|
WO2019150309A1
(en)
|
2018-02-02 |
2019-08-08 |
Hammack Scott |
Modulators of gpr68 and uses thereof for treating and preventing diseases
|
EP3752195A4
(de)
|
2018-02-14 |
2021-11-17 |
Viela Bio, Inc. |
Antikörper gegen felinen mcdonough-sarkom(fms)-ähnlichen tyrosinkinase-3-rezeptorliganden (flt3l) und verwendungen davon zur behandlung von autoimmun- und entzündungskrankheiten
|
JP2021515770A
(ja)
|
2018-03-05 |
2021-06-24 |
ヤンセン バイオテツク,インコーポレーテツド |
抗il−23特異的抗体を用いたクローン病の治療方法
|
WO2019177690A1
(en)
|
2018-03-12 |
2019-09-19 |
Zoetis Services Llc |
Anti-ngf antibodies and methods thereof
|
WO2019213619A1
(en)
|
2018-05-04 |
2019-11-07 |
Abbott Laboratories |
Hbv diagnostic, prognostic, and therapeutic methods and products
|
EP3794116A2
(de)
|
2018-05-17 |
2021-03-24 |
BP Corporation North America Inc. |
Herstellung von 2-keto-3-deoxy-d-gluconsäure in filamentösen pilzen
|
KR102480493B1
(ko)
|
2018-06-08 |
2022-12-21 |
크리스탈 바이오사이언스 주식회사 |
동일한 경쇄 i을 갖는 다양한 항체를 생산하기 위한 트랜스제닉 동물
|
WO2019244107A1
(en)
|
2018-06-21 |
2019-12-26 |
Daiichi Sankyo Company, Limited |
Compositions including cd3 antigen binding fragments and uses thereof
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
WO2020016838A2
(en)
|
2018-07-18 |
2020-01-23 |
Janssen Biotech, Inc. |
Sustained response predictors after treatment with anti-il23 specific antibody
|
US11548938B2
(en)
|
2018-08-21 |
2023-01-10 |
Quidel Corporation |
DbpA antibodies and uses thereof
|
US20210317467A1
(en)
|
2018-09-07 |
2021-10-14 |
Basf Plant Science Copmany Gmbh |
Improved method for the production of high levels of pufa in plants
|
WO2020049157A1
(en)
|
2018-09-07 |
2020-03-12 |
Basf Plant Science Company Gmbh |
Improved method for the production of high levels of pufa in plants
|
CN112969792A
(zh)
|
2018-09-07 |
2021-06-15 |
巴斯夫植物科学有限公司 |
用于在植物中产生高水平pufa的改进方法
|
DK3883606T5
(da)
|
2018-09-24 |
2024-01-02 |
Janssen Biotech Inc |
Sikker og effektiv fremgangsmåde til behandling af colitis ulcerosa med anti-il12/il23-antistof
|
JP2022512580A
(ja)
|
2018-10-05 |
2022-02-07 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
細菌バイオフィルムの酵素的破壊のための組成物および方法
|
JP2022504839A
(ja)
|
2018-10-10 |
2022-01-13 |
ティロス・セラピューティクス・インコーポレイテッド |
抗lap抗体変異体及びその使用
|
WO2020104943A2
(en)
|
2018-11-20 |
2020-05-28 |
Janssen Biotech, Inc. |
Safe and effective method of treating psoriasis with anti-il-23 specific antibody
|
WO2020106358A1
(en)
|
2018-11-20 |
2020-05-28 |
Takeda Vaccines, Inc. |
Novel anti-zika virus antibodies and uses thereof
|
US20200197517A1
(en)
|
2018-12-18 |
2020-06-25 |
Janssen Biotech, Inc. |
Safe and Effective Method of Treating Lupus with Anti-IL12/IL23 Antibody
|
US20220090125A1
(en)
|
2018-12-21 |
2022-03-24 |
Compass Therapeutics Llc |
Transgenic mouse expressing common human light chain
|
BR112021013903A2
(pt)
|
2019-01-15 |
2021-09-21 |
Janssen Biotech, Inc. |
Composições e métodos de anticorpos anti-tnf para o tratamento da artrite idiopática juvenil
|
WO2020152544A1
(en)
|
2019-01-23 |
2020-07-30 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions for use in methods for the treatment of psoriatic arthritis
|
EP3938391A1
(de)
|
2019-03-14 |
2022-01-19 |
Janssen Biotech, Inc. |
Verfahren zur herstellung von anti-tnf-antikörperzusammensetzungen
|
JP2022525145A
(ja)
|
2019-03-14 |
2022-05-11 |
ヤンセン バイオテツク,インコーポレーテツド |
抗il12/il23抗体組成物を生成するための製造方法
|
EP3938392A1
(de)
|
2019-03-14 |
2022-01-19 |
Janssen Biotech, Inc. |
Verfahren zur herstellung von anti-tnf-antikörperzusammensetzungen
|
CN113840838A
(zh)
|
2019-03-14 |
2021-12-24 |
詹森生物科技公司 |
用于产生抗tnf抗体组合物的制造方法
|
KR20210141583A
(ko)
|
2019-03-18 |
2021-11-23 |
얀센 바이오테크 인코포레이티드 |
항-il-12/il-23 항체를 사용한 소아 대상의 건선 치료 방법
|
KR20220005568A
(ko)
|
2019-05-09 |
2022-01-13 |
제넨테크, 인크. |
항체의 제조 방법
|
JP2022534020A
(ja)
|
2019-05-23 |
2022-07-27 |
ヤンセン バイオテツク,インコーポレーテツド |
Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
|
EP3976648A1
(de)
|
2019-06-03 |
2022-04-06 |
Janssen Biotech, Inc. |
Anti-tnf-antikörperzusammensetzungen und verfahren zur behandlung von aktiver psoriasis-arthritis
|
MX2021014882A
(es)
|
2019-06-03 |
2022-03-25 |
Janssen Biotech Inc |
Anticuerpos anti-tnf, composiciones y métodos para el tratamiento de la espondilitis anquilosante activa.
|
AU2020311897A1
(en)
|
2019-07-08 |
2022-02-03 |
Research Institute At Nationwide Children's Hospital |
Antibody compositions for disrupting biofilms
|
WO2021028752A1
(en)
|
2019-08-15 |
2021-02-18 |
Janssen Biotech, Inc. |
Anti-tfn antibodies for treating type i diabetes
|
JP2023507083A
(ja)
|
2019-12-19 |
2023-02-21 |
クイデル コーポレーション |
モノクローナル抗体融合物
|
EP4077658A1
(de)
|
2019-12-20 |
2022-10-26 |
Basf Se |
Vermindern der toxizität von terpenen und erhöhen des produktionspotenzials in mikroorganismen
|
CA3167027A1
(en)
|
2020-02-05 |
2021-08-12 |
Larimar Therapeutics, Inc. |
Tat peptide binding proteins and uses thereof
|
US20230272056A1
(en)
|
2020-04-09 |
2023-08-31 |
Merck Sharp & Dohme Llc |
Affinity matured anti-lap antibodies and uses thereof
|
WO2021211331A1
(en)
|
2020-04-13 |
2021-10-21 |
Abbott Point Of Care Inc. |
METHODS, COMPLEXES AND KITS FOR DETECTING OR DETERMINING AN AMOUNT OF A ß-CORONAVIRUS ANTIBODY IN A SAMPLE
|
WO2021221783A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
WO2021221782A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Chimeric antigen receptor-targeting ligands and uses thereof
|
EP4162061A1
(de)
|
2020-06-04 |
2023-04-12 |
Isobionics B.V. |
Synthetische santalensynthasen
|
US20230235352A1
(en)
|
2020-07-14 |
2023-07-27 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
US20220043000A1
(en)
|
2020-08-04 |
2022-02-10 |
Abbott Laboratories |
Methods and kits for detecting sars-cov-2 protein in a sample
|
US20220043003A1
(en)
|
2020-08-04 |
2022-02-10 |
Abbott Rapid Diagnostics International Unlimited Company |
Assays for detecting sars-cov-2
|
BR112023004415A2
(pt)
|
2020-09-11 |
2023-05-09 |
Medimmune Ltd |
Moléculas terapêuticas de ligação a b7-h4
|
EP4211663A2
(de)
|
2020-09-12 |
2023-07-19 |
MedImmune Limited |
Bewertungsverfahren für eine anti-b7h4-antikörper-wirkstoff-konjugattherapie
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
CA3198161A1
(en)
|
2020-12-01 |
2022-06-09 |
Beth MCQUISTON |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
EP4015626A1
(de)
|
2020-12-18 |
2022-06-22 |
Isobionics B.V. |
Enzyme und verfahren zur fermentativen herstellung von monoterpenestern
|
WO2022147147A1
(en)
|
2020-12-30 |
2022-07-07 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
KR20230146521A
(ko)
|
2021-01-13 |
2023-10-19 |
메모리얼 슬로안 케터링 캔서 센터 |
항체-피롤로벤조디아제핀 유도체 접합체
|
US20240115721A1
(en)
|
2021-01-13 |
2024-04-11 |
Memorial Sloan Kettering Cancer Center |
Anti-dll3 antibody-drug conjugate
|
UY39610A
(es)
|
2021-01-20 |
2022-08-31 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
EP4305062A1
(de)
|
2021-03-12 |
2024-01-17 |
Janssen Biotech, Inc. |
Verfahren zur behandlung von patienten mit psoriasisarthritis mit unzureichender reaktion auf eine tnf-therapie mit anti-il23-spezifischem antikörper
|
IL305802A
(en)
|
2021-03-12 |
2023-11-01 |
Janssen Biotech Inc |
A safe and effective method for the treatment of rheumatoid arthritis with a specific anti-IL23 antibody
|
CA3208011A1
(en)
|
2021-03-17 |
2022-09-22 |
Sarah Harris |
Methods of treating atopic dermatitis with anti il-13 antibodies
|
BR112023018331A2
(pt)
|
2021-03-18 |
2023-12-12 |
Medimmune Ltd |
Molécula terapêutica de ligação que se liga a ccr9
|
WO2022241057A1
(en)
|
2021-05-12 |
2022-11-17 |
Applied Biomedical Science Institute |
Binding polypeptides against sars cov-2 and uses thereof
|
AU2022279156A1
(en)
|
2021-05-18 |
2023-11-02 |
Abbott Laboratories |
Methods of evaluating brain injury in a pediatric subject
|
US20220372129A1
(en)
|
2021-05-20 |
2022-11-24 |
Janssen Biotech, Inc. |
Method of Treating Inflammatory Bowel Disease with a Combination Therapy of Antibodies to IL-23 and TNF Alpha
|
CA3222291A1
(en)
|
2021-06-14 |
2022-12-22 |
Jaime MARINO |
Methods of diagnosing or aiding in diagnosis of brain injury caused by acoustic energy, electromagnetic energy, an over pressurization wave, and/or blast wind
|
AU2022306973A1
(en)
|
2021-07-09 |
2024-02-22 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-il12/il23 antibody compositions
|
AU2022306144A1
(en)
|
2021-07-09 |
2024-02-22 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
US20230042465A1
(en)
|
2021-07-09 |
2023-02-09 |
Janssen Biotech, Inc. |
Manufacturing Methods for Producing Anti-TNF Antibody Compositions
|
WO2023012111A2
(en)
|
2021-08-02 |
2023-02-09 |
Basf Se |
Novel production of aroma compounds with ionylideneethane synthases
|
US11807685B2
(en)
|
2021-08-05 |
2023-11-07 |
The Uab Research Foundation |
Anti-CD47 antibody and uses thereof
|
WO2023028186A1
(en)
|
2021-08-27 |
2023-03-02 |
Abbott Laboratories |
Methods for detecting immunoglobulin g, subclass 4 (igg4) in a biological sample
|
WO2023034777A1
(en)
|
2021-08-31 |
2023-03-09 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
AU2022354059A1
(en)
|
2021-09-30 |
2024-03-28 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
WO2023073615A1
(en)
|
2021-10-29 |
2023-05-04 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
WO2023084488A1
(en)
|
2021-11-15 |
2023-05-19 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
US20230159633A1
(en)
|
2021-11-23 |
2023-05-25 |
Janssen Biotech, Inc. |
Method of Treating Ulcerative Colitis with Anti-IL23 Specific Antibody
|
WO2023114978A1
(en)
|
2021-12-17 |
2023-06-22 |
Abbott Laboratories |
Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
|
WO2023129942A1
(en)
|
2021-12-28 |
2023-07-06 |
Abbott Laboratories |
Use of biomarkers to determine sub-acute traumatic brain injury (tbi) in a subject having received a head computerized tomography (ct) scan that is negative for a tbi or no head ct scan
|
WO2023150652A1
(en)
|
2022-02-04 |
2023-08-10 |
Abbott Laboratories |
Lateral flow methods, assays, and devices for detecting the presence or measuring the amount of ubiquitin carboxy-terminal hydrolase l1 and/or glial fibrillary acidic protein in a sample
|
TW202348252A
(zh)
|
2022-02-16 |
2023-12-16 |
英商梅迪繆思有限公司 |
用治療性結合分子治療癌症的組合療法
|
WO2023187707A1
(en)
|
2022-03-30 |
2023-10-05 |
Janssen Biotech, Inc. |
Method of treating mild to moderate psoriasis with il-23 specific antibody
|
WO2023223265A1
(en)
|
2022-05-18 |
2023-11-23 |
Janssen Biotech, Inc. |
Method for evaluating and treating psoriatic arthritis with il23 antibody
|
WO2024006876A1
(en)
|
2022-06-29 |
2024-01-04 |
Abbott Laboratories |
Magnetic point-of-care systems and assays for determining gfap in biological samples
|
WO2024059708A1
(en)
|
2022-09-15 |
2024-03-21 |
Abbott Laboratories |
Biomarkers and methods for differentiating between mild and supermild traumatic brain injury
|
WO2024059692A1
(en)
|
2022-09-15 |
2024-03-21 |
Abbott Laboratories |
Hbv diagnostic, prognostic, and therapeutic methods and products
|