DE3672924D1 - Cystein verminderte muteine von biologisch aktiven menschlichen tnf-proteinen. - Google Patents

Cystein verminderte muteine von biologisch aktiven menschlichen tnf-proteinen.

Info

Publication number
DE3672924D1
DE3672924D1 DE8686901579T DE3672924T DE3672924D1 DE 3672924 D1 DE3672924 D1 DE 3672924D1 DE 8686901579 T DE8686901579 T DE 8686901579T DE 3672924 T DE3672924 T DE 3672924T DE 3672924 D1 DE3672924 D1 DE 3672924D1
Authority
DE
Germany
Prior art keywords
muteine
cystein
reduced
human tnf
tnf proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686901579T
Other languages
English (en)
Inventor
F Mark
S Lin
Yu Lu
M Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24807256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3672924(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cetus Corp filed Critical Cetus Corp
Application granted granted Critical
Publication of DE3672924D1 publication Critical patent/DE3672924D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE8686901579T 1985-02-07 1986-02-03 Cystein verminderte muteine von biologisch aktiven menschlichen tnf-proteinen. Expired - Lifetime DE3672924D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/698,939 US4959314A (en) 1984-11-09 1985-02-07 Cysteine-depleted muteins of biologically active proteins
PCT/US1986/000236 WO1986004606A1 (en) 1985-02-07 1986-02-03 Cysteine-depleted muteins of biologically active human tumor necrosis factor proteins

Publications (1)

Publication Number Publication Date
DE3672924D1 true DE3672924D1 (de) 1990-08-30

Family

ID=24807256

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686901579T Expired - Lifetime DE3672924D1 (de) 1985-02-07 1986-02-03 Cystein verminderte muteine von biologisch aktiven menschlichen tnf-proteinen.

Country Status (8)

Country Link
US (1) US4959314A (de)
EP (1) EP0213175B1 (de)
JP (1) JPS62501608A (de)
AU (1) AU5518086A (de)
DE (1) DE3672924D1 (de)
DK (1) DK172276B1 (de)
FI (1) FI99015C (de)
WO (1) WO1986004606A1 (de)

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AU5518086A (en) 1986-08-26
FI864036A (fi) 1986-10-06
WO1986004606A1 (en) 1986-08-14
EP0213175A1 (de) 1987-03-11
FI99015C (fi) 1997-09-25
DK478786A (da) 1986-12-08
EP0213175B1 (de) 1990-07-25
US4959314A (en) 1990-09-25

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