DE3682502D1 - Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests. - Google Patents
Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests.Info
- Publication number
- DE3682502D1 DE3682502D1 DE8686905538T DE3682502T DE3682502D1 DE 3682502 D1 DE3682502 D1 DE 3682502D1 DE 8686905538 T DE8686905538 T DE 8686905538T DE 3682502 T DE3682502 T DE 3682502T DE 3682502 D1 DE3682502 D1 DE 3682502D1
- Authority
- DE
- Germany
- Prior art keywords
- devices
- specific binding
- separating
- mixing
- label
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/806—Electrical property or magnetic property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76810885A | 1985-08-21 | 1985-08-21 | |
PCT/US1986/001720 WO1987001206A1 (en) | 1985-08-21 | 1986-08-21 | Methods and devices for separating, mixing, and detecting components in specific binding assays |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3682502D1 true DE3682502D1 (de) | 1991-12-19 |
Family
ID=25081541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686905538T Expired - Fee Related DE3682502D1 (de) | 1985-08-21 | 1986-08-21 | Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4868130A (de) |
EP (1) | EP0233939B1 (de) |
JP (1) | JP2591738B2 (de) |
KR (1) | KR880700269A (de) |
AT (1) | ATE69507T1 (de) |
CA (1) | CA1292092C (de) |
DE (1) | DE3682502D1 (de) |
WO (1) | WO1987001206A1 (de) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5073341A (en) * | 1985-08-21 | 1991-12-17 | Biotope, Inc. | Devices for conducting specific binding assays |
US5470711A (en) * | 1986-03-26 | 1995-11-28 | Synbiotics Corporation | Saliva enhancement reagent for feline leukemia virus elisa |
SE8703733L (sv) * | 1987-09-28 | 1989-03-29 | Ragnar Soedergaard | Analysmetod foer bestaemning av procent fri substans i biologiska vaetskor genom jaemviktsfoerdelning i olja/vatten system |
JP2854058B2 (ja) * | 1987-12-01 | 1999-02-03 | ベーリンガー マンヘイム コーポレイション | アッセイを実施するための方法及び装置 |
US5145784A (en) * | 1988-05-04 | 1992-09-08 | Cambridge Biotech Corporation | Double capture assay method employing a capillary flow device |
US5484735A (en) * | 1989-08-23 | 1996-01-16 | Northwestern University | Immunoassay of glycosylated proteins employing antibody directed to reductively glycosylated N-terminal amino acids |
CA2033010A1 (en) * | 1989-12-22 | 1991-06-23 | Rajeev Ramanathan | Method for separating components in a mixture |
US5279936A (en) * | 1989-12-22 | 1994-01-18 | Syntex (U.S.A.) Inc. | Method of separation employing magnetic particles and second medium |
US5223393A (en) * | 1990-06-12 | 1993-06-29 | Microgenics Corporation | Detection of analytes having binding sites for at least two binding moieties |
US6703236B2 (en) * | 1990-11-29 | 2004-03-09 | Applera Corporation | Thermal cycler for automatic performance of the polymerase chain reaction with close temperature control |
KR100236506B1 (ko) * | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
US5506114A (en) * | 1992-02-07 | 1996-04-09 | Osborn Laboratories | Methods and kits for detecting the presence or concentration of biological analytes |
US5629168A (en) * | 1992-02-10 | 1997-05-13 | British Technology Group Limited | Chemiluminescent enhancers |
GB2312746B (en) * | 1996-04-24 | 2000-07-19 | Molecular Light Technology Lim | Detection of an analyte in a Water Immiscible Solvent |
US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
US6143496A (en) * | 1997-04-17 | 2000-11-07 | Cytonix Corporation | Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly |
US6030582A (en) * | 1998-03-06 | 2000-02-29 | Levy; Abner | Self-resealing, puncturable container cap |
US6752965B2 (en) * | 1998-03-06 | 2004-06-22 | Abner Levy | Self resealing elastomeric closure |
JP3662850B2 (ja) * | 1998-06-24 | 2005-06-22 | イルミナ インコーポレイテッド | 微小球を有するアレイセンサーのデコード |
CA2283597C (en) | 1998-10-02 | 2008-02-05 | Ortho-Clinical Diagnostics, Inc. | Reduced cortisol conjugates |
EP1183104B1 (de) † | 1999-05-14 | 2006-10-25 | Gen-Probe Incorporated | Durchdringbare kappe mit innerer spitze |
US6623982B1 (en) * | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
EP1384076B1 (de) | 2001-03-19 | 2012-07-25 | Gyros Patent Ab | Charakterisierung von reaktionsvariablen |
WO2004065000A1 (en) | 2003-01-21 | 2004-08-05 | Illumina Inc. | Chemical reaction monitor |
US20050181513A1 (en) * | 2004-02-18 | 2005-08-18 | Viorica Lopez-Avila | Methods and compositions for assessing a sample by MAILDI mass spectrometry |
US7776531B1 (en) | 2004-03-25 | 2010-08-17 | Illumina, Inc. | Compositions and methods for stabilizing surface bound probes |
KR101228356B1 (ko) | 2004-04-08 | 2013-02-05 | 바이오매트리카 인코포레이티드 | 생명과학용 시료 보관 및 시료 관리의 통합 |
US9488665B2 (en) * | 2005-09-13 | 2016-11-08 | Chrome Red Technologies, Llc | Magnetic particle tagged reagents and techniques |
US20070113908A1 (en) * | 2005-11-18 | 2007-05-24 | The Ohio State University And Bioloc, Inc. | Valve for microfluidic chips |
US9274082B2 (en) * | 2007-08-27 | 2016-03-01 | Technion Research & Development Foundation Limited | pH gradients controlled by electrolysis, and their use in isoelectric focusing |
RU2533252C2 (ru) * | 2008-10-31 | 2014-11-20 | Биомерьё, Инк. | Способы разделения и характеристики микроорганизмов с помощью идентификатора |
JP5816164B2 (ja) * | 2009-05-07 | 2015-11-18 | ビオメリュー・インコーポレイテッド | 抗生物質耐性測定方法 |
US20100323343A1 (en) * | 2009-05-11 | 2010-12-23 | Nexus Dx, Inc. | Methods and compositions for analyte detection |
CN102472724B (zh) | 2009-08-18 | 2014-08-13 | 工业研究与发展基金会有限公司 | 分离分子分析物的方法和装置 |
WO2011021196A2 (en) | 2009-08-18 | 2011-02-24 | Technion Research & Development Foundation Ltd. | Proton concentration topographies, methods and devices for producing the same |
CA2784791A1 (en) * | 2009-12-17 | 2011-07-14 | Abaxis, Inc. | Novel assays for detecting analytes in samples and kits and compositions related thereto |
EP2598660B1 (de) | 2010-07-26 | 2017-03-15 | Biomatrica, INC. | Zusammensetzungen zur stabilisierung von dna, rna und proteinen in blut- und anderen biologischen proben während des transports und der lagerung bei umgebungstemperaturen |
EP2598661B1 (de) | 2010-07-26 | 2017-09-27 | Biomatrica, INC. | Zusammensetzungen zur stabilisierung von dna, rna und proteinen in speichel- und anderen biologischen proben während des transports und der lagerung bei umgebungstemperaturen |
US20130071946A1 (en) * | 2011-09-21 | 2013-03-21 | Roche Molecular Systems, Inc. | Suspension Container For Binding Particles For The Isolation Of Biological Material |
US20130164860A1 (en) * | 2011-11-04 | 2013-06-27 | Technion Research & Development Foundation Ltd. | Affinity methods and compositions employing electronic control of ph |
CN104023551A (zh) | 2011-11-04 | 2014-09-03 | 生物辐射实验室股份有限公司 | 细胞组分的同时纯化 |
US9766207B2 (en) | 2011-11-04 | 2017-09-19 | Bio-Rad Laboratories, Inc. | Affinity methods and compositions employing electronic control of pH |
EP2814597A4 (de) | 2012-02-15 | 2015-10-28 | Bio Rad Laboratories | Elektronische steuerung von ph-wert und ionenstärke |
US9321012B2 (en) | 2012-04-04 | 2016-04-26 | Bio-Rad Laboratories, Inc. | Electronic protein fractionation |
US20130280146A1 (en) * | 2012-04-18 | 2013-10-24 | Rarecyte, Inc. | Systems and methods for separation and analysis of target analytes |
EP2934572A4 (de) | 2012-12-20 | 2016-11-23 | Biomatrica Inc | Formulierungen und verfahren zur stabilisierung von pcr-reagenzien |
US10364453B1 (en) * | 2013-02-04 | 2019-07-30 | The United States Of America, As Represented By The Secretary Of The Navy | Detecting of bacteria using fluorescently-labeled phage immobilized on an optically transparent surface |
WO2014144209A1 (en) | 2013-03-15 | 2014-09-18 | Abbott Molecular Inc. | One-step procedure for the purification of nucleic acids |
EP3942931A1 (de) | 2014-06-10 | 2022-01-26 | Biomatrica, INC. | Stabilisierung von thrombozyten bei umgebungstemperatur |
EP3387411B1 (de) | 2015-12-08 | 2023-05-10 | Biomatrica, INC. | Verringerung der erythrozytensedimentationsrate |
CA3010823C (en) * | 2016-01-08 | 2021-01-26 | Siemens Healthcare Diagnostics Inc. | Heating element for sensor array |
IT201600079328A1 (it) * | 2016-07-28 | 2018-01-28 | Altergon Sa | Metodo migliorato per la decontaminazione di materiale biologico mediante partizione e inattivazione |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1411382A (en) * | 1971-12-16 | 1975-10-22 | Radiochemical Centre Ltd | Methods of analysis |
US3852194A (en) * | 1972-12-11 | 1974-12-03 | Corning Glass Works | Apparatus and method for fluid collection and partitioning |
GB1566098A (en) * | 1975-11-14 | 1980-04-30 | Nat Res Dev | Separation of solid and liquid components of mixtures |
GB1533272A (en) * | 1976-02-13 | 1978-11-22 | Radiochemical Centre Ltd | Centrifuge tube |
IL56839A0 (en) * | 1979-03-11 | 1979-05-31 | Technion Res & Dev Foundation | Improvement in specific binding assay technique |
IL58943A (en) * | 1979-12-12 | 1983-05-15 | Cais Michael | Method and device for mass transfer operations in immunoassays and other applications |
JPS58205854A (ja) * | 1982-05-25 | 1983-11-30 | Mihama Hisaharu | 潜血反応検査用の固定化抗体 |
DE3222962A1 (de) * | 1982-06-19 | 1983-12-22 | Bayer Ag, 5090 Leverkusen | Siliconpasten fuer die trennung von blutproben |
AU1912783A (en) * | 1982-09-15 | 1984-03-22 | Ortho Diagnostic Systems Inc. | Carousel microparticle separating, washing + reading device |
FI844027A (fi) * | 1984-10-12 | 1986-04-13 | Labsystems Oy | Immunologiskt bestaemningsfoerfarande. |
-
1986
- 1986-08-21 CA CA000516560A patent/CA1292092C/en not_active Expired - Fee Related
- 1986-08-21 DE DE8686905538T patent/DE3682502D1/de not_active Expired - Fee Related
- 1986-08-21 JP JP61504751A patent/JP2591738B2/ja not_active Expired - Fee Related
- 1986-08-21 WO PCT/US1986/001720 patent/WO1987001206A1/en active IP Right Grant
- 1986-08-21 AT AT86905538T patent/ATE69507T1/de not_active IP Right Cessation
- 1986-08-21 EP EP86905538A patent/EP0233939B1/de not_active Expired - Lifetime
-
1987
- 1987-02-20 US US07/017,318 patent/US4868130A/en not_active Expired - Lifetime
- 1987-04-21 KR KR870700345A patent/KR880700269A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0233939B1 (de) | 1991-11-13 |
ATE69507T1 (de) | 1991-11-15 |
KR880700269A (ko) | 1988-02-22 |
JPS63501172A (ja) | 1988-04-28 |
JP2591738B2 (ja) | 1997-03-19 |
CA1292092C (en) | 1991-11-12 |
WO1987001206A1 (en) | 1987-02-26 |
EP0233939A1 (de) | 1987-09-02 |
US4868130A (en) | 1989-09-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |