DE3687551T2 - Implantate mit verzoegerter abgabe fuer die anwendung von rekombinanten wachstumshormonen. - Google Patents

Implantate mit verzoegerter abgabe fuer die anwendung von rekombinanten wachstumshormonen.

Info

Publication number
DE3687551T2
DE3687551T2 DE8686305431T DE3687551T DE3687551T2 DE 3687551 T2 DE3687551 T2 DE 3687551T2 DE 8686305431 T DE8686305431 T DE 8686305431T DE 3687551 T DE3687551 T DE 3687551T DE 3687551 T2 DE3687551 T2 DE 3687551T2
Authority
DE
Germany
Prior art keywords
implants
application
growth hormones
delayed delivery
recombinant growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686305431T
Other languages
English (en)
Other versions
DE3687551D1 (de
Inventor
Alvin M Janski
Ren-Der Yang
Kallidaikuric Sivaramakrishnan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
International Minerals and Chemical Corp
Original Assignee
International Minerals and Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by International Minerals and Chemical Corp filed Critical International Minerals and Chemical Corp
Application granted granted Critical
Publication of DE3687551D1 publication Critical patent/DE3687551D1/de
Publication of DE3687551T2 publication Critical patent/DE3687551T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH] (Somatotropin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE8686305431T 1985-07-15 1986-07-15 Implantate mit verzoegerter abgabe fuer die anwendung von rekombinanten wachstumshormonen. Expired - Fee Related DE3687551T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/755,093 US4786501A (en) 1985-07-15 1985-07-15 Cylindrical implants for the controlled release of growth hormones

Publications (2)

Publication Number Publication Date
DE3687551D1 DE3687551D1 (de) 1993-03-04
DE3687551T2 true DE3687551T2 (de) 1993-05-13

Family

ID=25037706

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686305431T Expired - Fee Related DE3687551T2 (de) 1985-07-15 1986-07-15 Implantate mit verzoegerter abgabe fuer die anwendung von rekombinanten wachstumshormonen.

Country Status (18)

Country Link
US (1) US4786501A (de)
EP (1) EP0210039B1 (de)
JP (2) JPH0822820B2 (de)
KR (1) KR930008952B1 (de)
CN (1) CN1026862C (de)
AT (1) ATE84707T1 (de)
AU (1) AU604639B2 (de)
BR (1) BR8603315A (de)
CA (1) CA1288196C (de)
DE (1) DE3687551T2 (de)
DK (1) DK173165B1 (de)
ES (1) ES2002099A6 (de)
IE (1) IE62302B1 (de)
IL (1) IL79403A0 (de)
MX (1) MX173196B (de)
NZ (1) NZ216832A (de)
PT (1) PT82978B (de)
ZA (1) ZA865271B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137874A (en) * 1985-07-29 1992-08-11 American Cyanamid Co. Partially coated C10 -C20 fatty acid salts of peptides having molecular weights up to about 5,000
US4761289A (en) * 1986-10-10 1988-08-02 International Minerals & Chemical Corp. Sustained release implant and method for preparing same
US4863736A (en) * 1987-03-16 1989-09-05 Monsanto Company Somatotropin prolonged release
US4837202A (en) * 1987-09-14 1989-06-06 Pitman-Moore, Inc. Method for stimulating the immune system
US5035891A (en) * 1987-10-05 1991-07-30 Syntex (U.S.A.) Inc. Controlled release subcutaneous implant
US5100668A (en) * 1988-06-14 1992-03-31 Massachusetts Institute Of Technology Controlled release systems containing heparin and growth factors
ATE130195T1 (de) * 1988-07-26 1995-12-15 Univ Rutgers Vorrichtungen und verfahren zur wachstumsförderung bei bratgeflügel.
US5179080A (en) * 1989-08-31 1993-01-12 Clinical Homecare, Corp. Formulations containing growth hormone and nutritional supplements, and methods of treating malnutrition in chronic lung disease
US5091185A (en) * 1990-06-20 1992-02-25 Monsanto Company Coated veterinary implants
US5232708A (en) * 1990-06-20 1993-08-03 Monsanto Company Coated veterinary implants
US5922342A (en) * 1990-10-01 1999-07-13 Pharmacia & Upjohn Company Lateral edge coated controlled release pharmaceutical compositions
IS3778A7 (is) * 1990-10-31 1992-05-02 Amgen Inc. Aðferð til að gefa dýrum vaxtarhormón, þar sem gefnu magni er stýrt
SE9303068D0 (sv) * 1993-09-21 1993-09-21 Kabi Pharmacia Ab New use
DE69420872T2 (de) * 1994-06-17 2000-01-13 Applied Research Systems Hgh enthaltende pharmazeutische zubereitungen
US5672357A (en) * 1994-07-01 1997-09-30 Monsanto Company Method and device for implantation of large diameter objects in bovines
US5595752A (en) * 1994-07-01 1997-01-21 Monsanto Company Increasing dressing percentage and carcass weight in finishing beef cattle
IT1269221B (it) 1994-11-25 1997-03-21 Fondazione Clinica Del Lavoro Campionatore diffusivo a simmetria radiale di sostanze volatili, ad alta capacita' di pompaggio equivalente ed utile per il desorbimento chimico e termico.
AU744606B2 (en) * 1996-12-20 2002-02-28 Scientec Research Pty Ltd Apparatus and method for coating a material
AUPO431596A0 (en) * 1996-12-20 1997-01-23 Scientec Research Pty Ltd Apparatus and method for coating a material
KR19990071255A (ko) 1998-02-28 1999-09-15 성재갑 소마토트로핀과 비타민의 합제 조성물
CA2325983C (en) * 1998-04-20 2009-02-17 Genzyme Corporation Drug delivery of proteins from polymeric blends
AU2002324447B2 (en) * 2001-06-22 2006-06-29 Durect Corporation Zero-order prolonged release coaxial implants
AUPR602401A0 (en) * 2001-06-29 2001-07-26 Smart Drug Systems Inc Sustained release delivery system
US20060051347A1 (en) 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
US8936805B2 (en) 2005-09-09 2015-01-20 Board Of Trustees Of The University Of Arkansas Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same
US9763788B2 (en) 2005-09-09 2017-09-19 Board Of Trustees Of The University Of Arkansas Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same
WO2007030752A2 (en) * 2005-09-09 2007-03-15 University Of Arkansas At Little Rock System and method for tissue generation and bone regeneration

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4450150A (en) * 1973-05-17 1984-05-22 Arthur D. Little, Inc. Biodegradable, implantable drug delivery depots, and method for preparing and using the same
US3993072A (en) * 1974-08-28 1976-11-23 Alza Corporation Microporous drug delivery device
US4158526A (en) * 1978-01-09 1979-06-19 General Electric Company Turbine assembly including a rotatable liquid collection ring
US4443539A (en) * 1980-02-05 1984-04-17 The Upjohn Company Process for preparing bovine growth hormone
IL59690A (en) * 1980-03-24 1983-11-30 Yeda Res & Dev Production of bovine growth hormone by microorganisms and modified microorganisms adapted to produce it
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
EP0085036A1 (de) * 1982-01-18 1983-08-03 Monsanto Company Verfahren zur Verbesserung der Rindermilchproduktion
DE3214667C2 (de) * 1982-04-21 1985-07-18 Akzo Gmbh, 5600 Wuppertal Zusammengesetzter Körper für die Langzeitabgabe von Wirkstoffen
CA1224432A (en) * 1982-08-17 1987-07-21 Gary N. Buell Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield
CA1341012C (en) * 1982-09-27 2000-06-06 Biogen, Inc. Dna sequences, recombinant dna molecules and processes for producing swine growth hormone-like polypeptides
US4511503A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4511502A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4512922A (en) * 1982-12-22 1985-04-23 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4576604A (en) * 1983-03-04 1986-03-18 Alza Corporation Osmotic system with instant drug availability
US4506680A (en) * 1983-03-17 1985-03-26 Medtronic, Inc. Drug dispensing body implantable lead
US4755465A (en) * 1983-04-25 1988-07-05 Genentech, Inc. Secretion of correctly processed human growth hormone in E. coli and Pseudomonas
US4563489A (en) * 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
JPH082298B2 (ja) * 1984-05-11 1996-01-17 コ−ドン・ジェネティック・エンジニアリング・ラボラトリ−ズ ポリペプチド前駆体を単離する方法
US4686098A (en) * 1984-05-14 1987-08-11 Merck & Co., Inc. Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo
EP0193917A3 (de) * 1985-03-06 1987-09-23 American Cyanamid Company Wasserdispersible und wasserlösliche Polymerzusammensetzungen für parenterale Anwendung
US4670249A (en) * 1985-04-12 1987-06-02 International Minerals & Chemical Corp. Growth-promoting compositions
US4666704A (en) * 1985-05-24 1987-05-19 International Minerals & Chemical Corp. Controlled release delivery system for macromolecules

Also Published As

Publication number Publication date
PT82978A (en) 1986-08-01
CN86105858A (zh) 1987-06-03
IE861876L (en) 1987-01-15
JPH0822820B2 (ja) 1996-03-06
EP0210039A2 (de) 1987-01-28
ES2002099A6 (es) 1988-07-16
MX173196B (es) 1994-02-07
BR8603315A (pt) 1987-02-24
KR870000924A (ko) 1987-03-10
DE3687551D1 (de) 1993-03-04
DK336986D0 (da) 1986-07-15
EP0210039A3 (en) 1988-07-06
DK336986A (da) 1987-01-16
US4786501A (en) 1988-11-22
DK173165B1 (da) 2000-02-21
JPS6253928A (ja) 1987-03-09
JPH08205888A (ja) 1996-08-13
KR930008952B1 (ko) 1993-09-17
ATE84707T1 (de) 1993-02-15
ZA865271B (en) 1987-03-25
AU6020186A (en) 1987-01-22
EP0210039B1 (de) 1993-01-20
CN1026862C (zh) 1994-12-07
PT82978B (pt) 1988-07-01
IL79403A0 (en) 1986-10-31
AU604639B2 (en) 1991-01-03
CA1288196C (en) 1991-08-27
NZ216832A (en) 1989-01-06
IE62302B1 (en) 1995-01-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee