DE3687751T2 - Kolonne zum entfernen von beta-2-mikroglobulin. - Google Patents

Kolonne zum entfernen von beta-2-mikroglobulin.

Info

Publication number
DE3687751T2
DE3687751T2 DE8686905431T DE3687751T DE3687751T2 DE 3687751 T2 DE3687751 T2 DE 3687751T2 DE 8686905431 T DE8686905431 T DE 8686905431T DE 3687751 T DE3687751 T DE 3687751T DE 3687751 T2 DE3687751 T2 DE 3687751T2
Authority
DE
Germany
Prior art keywords
microglobulin
column
removing beta
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686905431T
Other languages
English (en)
Other versions
DE3687751D1 (de
Inventor
Nobuo Ida
Hiroshi Kataoka
Tetsunosuke Kunitomo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Publication of DE3687751D1 publication Critical patent/DE3687751D1/de
Application granted granted Critical
Publication of DE3687751T2 publication Critical patent/DE3687751T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0415—Plasma
    • A61M2202/0421—Beta-2-microglobulin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • External Artificial Organs (AREA)
DE8686905431T 1985-09-19 1986-09-18 Kolonne zum entfernen von beta-2-mikroglobulin. Expired - Fee Related DE3687751T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20725085 1985-09-19
PCT/JP1986/000485 WO1987001597A1 (fr) 1985-09-19 1986-09-18 COLONNE D'EXTRACTION DE beta2-MICROGLOBULINE

Publications (2)

Publication Number Publication Date
DE3687751D1 DE3687751D1 (de) 1993-03-25
DE3687751T2 true DE3687751T2 (de) 1993-05-27

Family

ID=16536693

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686905431T Expired - Fee Related DE3687751T2 (de) 1985-09-19 1986-09-18 Kolonne zum entfernen von beta-2-mikroglobulin.

Country Status (5)

Country Link
US (1) US4770774A (de)
EP (1) EP0236509B1 (de)
JP (1) JPH06104122B1 (de)
DE (1) DE3687751T2 (de)
WO (1) WO1987001597A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073265A (en) * 1987-02-27 1991-12-17 Johnson Richard J Methods of manufacturing nucleophilic material modified for improved biocompatibility
EP0319144A1 (de) * 1987-11-06 1989-06-07 Asahi Kasei Kogyo Kabushiki Kaisha Sorbentmittel für beta-2-Mikroglobulin
EP0319862B1 (de) * 1987-12-11 1994-01-12 Akzo Nobel N.V. Biocompatible Dialysemembran aus Cellulose mit erhöhter Beta-2-Microglobulinadsorption
US5085779A (en) * 1989-06-07 1992-02-04 J. T. Baker, Inc. Polyethyleneimine matrixes for affinity chromatography
US5092992A (en) * 1989-06-07 1992-03-03 J. T. Baker Inc. Polyethyleneimine matrixes for affinity chromatography
US20020164818A1 (en) * 1995-05-23 2002-11-07 Gruber Karl F. Mass spectrometric immunoassay analysis of specific proteins and variants present in various biological fluids
US6878269B2 (en) * 1996-01-31 2005-04-12 Kaneka Corporation Device for body fluid purification and system for body fluid purification
EP0819439B1 (de) * 1996-01-31 2005-11-30 Kaneka Corporation Vorrichtung mit adsorbens zum adsorptiven entfernen von krankheitsbedingten faktoren in körperflüssigkeiten
FR2785200B1 (fr) 1998-10-30 2001-03-30 Centre Nat Rech Scient Utilisation d'un gel adsorbant pour eliminer et purifier les biomolecules
EP1066843B1 (de) * 1998-12-24 2011-08-24 Toray Industries, Inc. Säule zur blutreinigung
UA81216C2 (en) * 1999-06-01 2007-12-25 Prevention and treatment of amyloid disease
EP1315551B1 (de) * 1999-06-03 2015-11-04 Advanced Extravascular Systems Entfernung von unerwünschten molekülen aus zirkulierendem blut in einem schritt
US8865172B2 (en) 2000-05-08 2014-10-21 Advanced Extravascular Systems, Inc. Method for reducing the number of unwanted molecules in bodily fluids
JP4643445B2 (ja) * 2002-11-12 2011-03-02 ベクトン，ディッキンソン アンド カンパニー バイオマーカープロフィールを使用した敗血症またはｓｉｒｓの診断
AU2003303198A1 (en) 2002-12-19 2004-07-14 New York University Method for treating amyloid disease
AT413336B (de) * 2003-09-12 2006-02-15 Mattner Frank Dr Apherese-vorrichtung
WO2005063335A2 (en) * 2003-12-30 2005-07-14 Statens Serum Institut MONOCLONAL DES-LYS58-β2-MICROGLOBULIN ANTIBODIES FOR MEASUREMENT AND MANAGEMENT OF HEMODIALYSIS COMPLICATIONS
WO2006113529A2 (en) * 2005-04-15 2006-10-26 Becton, Dickinson And Company Diagnosis of sepsis
AT502691A1 (de) * 2005-10-24 2007-05-15 Univ Fuer Weiterbildung Krems Extrakorporales blut- oder plasmareinigungssystem
WO2009123737A2 (en) 2008-04-03 2009-10-08 Becton, Dickinson And Company Advanced detection of sepsis
WO2011046504A1 (en) * 2009-10-18 2011-04-21 Glycorex Ab Method and product for blood treatment and purification
US20160208011A1 (en) 2010-01-28 2016-07-21 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
KR20180030965A (ko) * 2015-05-18 2018-03-27 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 노화 관련 장애를 치료하기 위한 방법 및 조성물
KR20220062668A (ko) 2015-06-15 2022-05-17 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 노화와 연관된 질환을 치료하기 위한 방법 및 조성물
EP3192806A1 (de) 2016-01-13 2017-07-19 Affiris AG Alpha-kette des hochaffinen ige-rezeptors (fceria)
CN114272901A (zh) 2016-08-01 2022-04-05 株式会社钟化 钙蛋白粒子的吸附材料以及吸附除去系统及其利用方法
DE102017210134A1 (de) 2016-12-15 2018-06-21 Fresenius Medical Care Deutschland Gmbh System zur extrakorporalen Blutbehandlung, Behandlungsvorrichtung, Kit und Verfahren zum Betreiben eines Systems zur extrakorporalen Blutbehandlung
US20190117869A1 (en) * 2017-10-24 2019-04-25 DD Innovations Lab, LLC Apparatus and methods to remove toxins from blood by plasmapheresis
DE102017131192A1 (de) 2017-12-22 2019-06-27 Fresenius Medical Care Deutschland Gmbh Pufferlösung zur Reduzierung des Kohlendioxidgehaltes in extrakorporalem Blut

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3669878A (en) * 1968-12-02 1972-06-13 Health Education And Welfare U Treatment of dialysate solution for removal of urea
JPS5437821A (en) * 1977-08-29 1979-03-20 Seikagaku Kogyo Co Ltd Blood cells sensitized to antibody against anti-beta2-microglobulin of man, their preparation and determination of beta2-microglobulin of man
JPS5530652A (en) * 1978-08-28 1980-03-04 Seikagaku Kogyo Co Ltd Latex sensitive to antibody of human beta2-microglobulin for quantitizing human beta2-microglobulin and its composite
US4257884A (en) * 1979-04-17 1981-03-24 Damon Corporation Chromatography
JPS5693046A (en) * 1979-11-20 1981-07-28 Fujirebio Inc Determination of beta2-microglobulin by enzime immunity measuring method
US4321192A (en) * 1980-01-10 1982-03-23 Ionics Incorporated Fractionation of protein mixtures by salt addition followed by dialysis treatment
US4329152A (en) * 1980-10-06 1982-05-11 International Lead Zinc Research Organization, Inc. Determination of β2 -microglobulin in human urine and serum by latex immunoassay
DE3206729A1 (de) * 1982-02-25 1983-09-01 Behringwerke Ag, 3550 Marburg Immunologisches agglutinationsverfahren

Also Published As

Publication number Publication date
EP0236509B1 (de) 1993-02-10
US4770774A (en) 1988-09-13
DE3687751D1 (de) 1993-03-25
EP0236509A1 (de) 1987-09-16
JPH06104122B1 (de) 1994-12-21
EP0236509A4 (de) 1989-05-30
WO1987001597A1 (fr) 1987-04-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee