DE3782434D1 - Kovalent gebundene mittel mit kohlenstoffionen-gruppen. - Google Patents

Kovalent gebundene mittel mit kohlenstoffionen-gruppen.

Info

Publication number
DE3782434D1
DE3782434D1 DE8787906338T DE3782434T DE3782434D1 DE 3782434 D1 DE3782434 D1 DE 3782434D1 DE 8787906338 T DE8787906338 T DE 8787906338T DE 3782434 T DE3782434 T DE 3782434T DE 3782434 D1 DE3782434 D1 DE 3782434D1
Authority
DE
Germany
Prior art keywords
compositions
active agents
base groups
covalently bonded
covalent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787906338T
Other languages
English (en)
Other versions
DE3782434T2 (de
Inventor
Robert F Helwing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE3782434D1 publication Critical patent/DE3782434D1/de
Application granted granted Critical
Publication of DE3782434T2 publication Critical patent/DE3782434T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
DE8787906338T 1986-09-26 1987-09-03 Kovalent gebundene mittel mit kohlenstoffionen-gruppen. Expired - Fee Related DE3782434T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/912,352 US4842868A (en) 1986-09-26 1986-09-26 Covalently bonded active agents with carbonium ion base groups
PCT/US1987/002228 WO1988002252A1 (en) 1986-09-26 1987-09-03 Covalently bonded active agents with carbonium ion base groups
CA000574727A CA1321577C (en) 1986-09-26 1988-08-15 Covalently bonded active agents with carbonium ion base groups

Publications (2)

Publication Number Publication Date
DE3782434D1 true DE3782434D1 (de) 1992-12-03
DE3782434T2 DE3782434T2 (de) 1993-03-11

Family

ID=25672052

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787906338T Expired - Fee Related DE3782434T2 (de) 1986-09-26 1987-09-03 Kovalent gebundene mittel mit kohlenstoffionen-gruppen.

Country Status (7)

Country Link
US (1) US4842868A (de)
EP (1) EP0321499B1 (de)
AT (1) ATE81772T1 (de)
AU (1) AU614498B2 (de)
CA (1) CA1321577C (de)
DE (1) DE3782434T2 (de)
WO (1) WO1988002252A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5456904A (en) * 1993-06-28 1995-10-10 The Procter & Gamble Company Photoprotection compositions comprising certain chelating agents
US20050152950A1 (en) * 1995-11-13 2005-07-14 Saffran Bruce N. Method and apparatus for macromolecular delivery using a coated membrane
CA2497195C (en) * 2001-12-14 2014-07-08 The University Of Wyoming Methods and compositions for controlled release of drugs
US9050393B2 (en) 2005-02-08 2015-06-09 Bruce N. Saffran Medical devices and methods for modulation of physiology using device-based surface chemistry
GB0908781D0 (en) 2009-05-21 2009-07-01 Cadbury Uk Ltd Confectionery product

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304767A (en) * 1980-05-15 1981-12-08 Sri International Polymers of di- (and higher functionality) ketene acetals and polyols
US4532335A (en) * 1983-03-07 1985-07-30 Sri International Preparation of ketene acetals by rearrangement of allyl and substituted allyl acetals
US4610870A (en) * 1984-10-05 1986-09-09 E. R. Squibb & Sons, Inc. Controlled release formulation
GB8430252D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
NZ217821A (en) * 1985-10-10 1989-07-27 Biotech Australia Pty Ltd Oral delivery system; complex of active agent and vitamin b12 or analogue thereof

Also Published As

Publication number Publication date
ATE81772T1 (de) 1992-11-15
WO1988002252A1 (en) 1988-04-07
AU614498B2 (en) 1991-09-05
US4842868A (en) 1989-06-27
EP0321499A4 (de) 1990-04-10
EP0321499A1 (de) 1989-06-28
EP0321499B1 (de) 1992-10-28
AU8032587A (en) 1988-04-21
DE3782434T2 (de) 1993-03-11
CA1321577C (en) 1993-08-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee