DE3878239T2 - Kristalle aus menschlichem serumalbumin und verfahren zu deren herstellung. - Google Patents
Kristalle aus menschlichem serumalbumin und verfahren zu deren herstellung.Info
- Publication number
- DE3878239T2 DE3878239T2 DE8888402228T DE3878239T DE3878239T2 DE 3878239 T2 DE3878239 T2 DE 3878239T2 DE 8888402228 T DE8888402228 T DE 8888402228T DE 3878239 T DE3878239 T DE 3878239T DE 3878239 T2 DE3878239 T2 DE 3878239T2
- Authority
- DE
- Germany
- Prior art keywords
- crystals
- production
- human serum
- serum albumine
- albumine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- C—CHEMISTRY; METALLURGY
- C30—CRYSTAL GROWTH
- C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
- C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
- C30B29/54—Organic compounds
- C30B29/58—Macromolecular compounds
-
- C—CHEMISTRY; METALLURGY
- C30—CRYSTAL GROWTH
- C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
- C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/30—Self-sustaining carbon mass or layer with impregnant or other layer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31536—Including interfacial reaction product of adjacent layers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31725—Of polyamide
- Y10T428/31768—Natural source-type polyamide [e.g., casein, gelatin, etc.]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/087,281 US4833233A (en) | 1987-08-20 | 1987-08-20 | Human serum albumin crystals and method of preparation |
EP88402228A EP0357857B1 (de) | 1987-08-20 | 1988-09-05 | Kristalle aus menschlichem Serumalbumin und Verfahren zu deren Herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3878239D1 DE3878239D1 (de) | 1993-03-18 |
DE3878239T2 true DE3878239T2 (de) | 1993-09-09 |
Family
ID=22204235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888402228T Expired - Fee Related DE3878239T2 (de) | 1987-08-20 | 1988-09-05 | Kristalle aus menschlichem serumalbumin und verfahren zu deren herstellung. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4833233A (de) |
EP (1) | EP0357857B1 (de) |
JP (1) | JPH064677B2 (de) |
AU (1) | AU604958B2 (de) |
CA (1) | CA1336530C (de) |
DE (1) | DE3878239T2 (de) |
FR (1) | FR2619567B1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3927345A1 (de) * | 1989-08-18 | 1991-02-21 | Biotechnolog Forschung Gmbh | Verfahren zur strukturbestimmung von peptiden |
US5866114A (en) * | 1992-06-09 | 1999-02-02 | Chiron Corporation | Crystallization of M-CSFα |
US5728553A (en) * | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
US5554522A (en) * | 1994-04-28 | 1996-09-10 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Dihydrodipicolinate reductase crystals and three dimensional structure |
US5585466A (en) * | 1994-12-06 | 1996-12-17 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Crystals of serum albumin for use in genetic engineering and rational drug design |
US5641681A (en) * | 1995-04-17 | 1997-06-24 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Device and method for screening crystallization conditions in solution crystal growth |
US5978740A (en) * | 1995-08-09 | 1999-11-02 | Vertex Pharmaceuticals Incorporated | Molecules comprising a calcineurin-like binding pocket and encoded data storage medium capable of graphically displaying them |
US6128582A (en) | 1996-04-30 | 2000-10-03 | Vertex Pharmaceuticals Incorporated | Molecules comprising an IMPDH-like binding pocket and encoded data storage medium capable of graphically displaying them |
US6153579A (en) | 1996-09-12 | 2000-11-28 | Vertex Pharmaceuticals, Incorporated | Crystallizable compositions comprising a hepatitis C virus NS3 protease domain/NS4A complex |
US6020162A (en) * | 1997-06-13 | 2000-02-01 | The Rockefeller University | Crystal of a protein-ligand complex containing an N-terminal truncated eIF4E, and methods of use thereof |
US5872011A (en) * | 1997-06-13 | 1999-02-16 | The Rockefeller University | Crystal of a protein-ligand complex containing an N-terminal truncated eIF4E, and methods of use thereof |
US6183121B1 (en) | 1997-08-14 | 2001-02-06 | Vertex Pharmaceuticals Inc. | Hepatitis C virus helicase crystals and coordinates that define helicase binding pockets |
US7383135B1 (en) * | 1998-05-04 | 2008-06-03 | Vertex Pharmaceuticals Incorporated | Methods of designing inhibitors for JNK kinases |
GB9902000D0 (en) | 1999-01-30 | 1999-03-17 | Delta Biotechnology Ltd | Process |
US20020042046A1 (en) * | 1999-02-25 | 2002-04-11 | Vertex Pharmaceuticals, Incorporated | Crystallizable compositions comprising a hepatitis C virus NS3 protease domain/NS4A complex |
US7247490B2 (en) * | 1999-04-06 | 2007-07-24 | Uab Research Foundation | Method for screening crystallization conditions in solution crystal growth |
US7244396B2 (en) * | 1999-04-06 | 2007-07-17 | Uab Research Foundation | Method for preparation of microarrays for screening of crystal growth conditions |
US7250305B2 (en) * | 2001-07-30 | 2007-07-31 | Uab Research Foundation | Use of dye to distinguish salt and protein crystals under microcrystallization conditions |
EP1701159A3 (de) * | 1999-04-06 | 2007-07-25 | University of Alabama | Verfahren zum Screening von Kristallisationsbedingungen für das Kristallwachstum von Proteinen in Lösung |
MXPA01009999A (es) * | 1999-04-06 | 2003-07-14 | Uab Research Foundation | Metodo para examinar las condiciones de cristalizacion en el crecimiento de cristales en solucion. |
US20030022383A1 (en) * | 1999-04-06 | 2003-01-30 | Uab Research Foundation | Method for screening crystallization conditions in solution crystal growth |
US7214540B2 (en) * | 1999-04-06 | 2007-05-08 | Uab Research Foundation | Method for screening crystallization conditions in solution crystal growth |
US6630006B2 (en) * | 1999-06-18 | 2003-10-07 | The Regents Of The University Of California | Method for screening microcrystallizations for crystal formation |
US6296673B1 (en) | 1999-06-18 | 2001-10-02 | The Regents Of The University Of California | Methods and apparatus for performing array microcrystallizations |
EP1358209B1 (de) * | 2001-02-09 | 2006-12-27 | Genentech, Inc. | Kristallisierung von igf-1 |
US7691872B2 (en) * | 2001-03-20 | 2010-04-06 | University Of Kentucky Research Foundation | Methods and compositions for optimizing blood and tissue stability of camptothecin and other albumin-binding therapeutic compounds |
US7670429B2 (en) * | 2001-04-05 | 2010-03-02 | The California Institute Of Technology | High throughput screening of crystallization of materials |
NZ529767A (en) * | 2001-06-13 | 2005-10-28 | Taurus Hsa Llc | Purification of human serum albumin |
KR20030022917A (ko) * | 2001-09-11 | 2003-03-19 | 크리스탈지노믹스(주) | 소테이즈의 결정화 방법 |
US20040137518A1 (en) * | 2002-01-31 | 2004-07-15 | Lambert Millard Hurst | CRYSTALLIZED PPARa LIGAND BINDING DOMAIN POLYPEPTIDE AND SCREENING METHODS EMPLOYING SAME |
US20070026528A1 (en) * | 2002-05-30 | 2007-02-01 | Delucas Lawrence J | Method for screening crystallization conditions in solution crystal growth |
WO2004005898A1 (en) * | 2002-07-10 | 2004-01-15 | Uab Research Foundation | Method for distinguishing between biomolecule and non-biomolecule crystals |
JP3567988B2 (ja) * | 2002-07-11 | 2004-09-22 | 独立行政法人理化学研究所 | 生体高分子の結晶化条件探査方法及び探査装置 |
CA2506317A1 (en) * | 2002-11-18 | 2004-06-03 | Taurus Hsa Llc | Method for continuous, automated blending of solutions from acids and bases |
US7087719B2 (en) * | 2002-11-19 | 2006-08-08 | Gtc Biotherapeutics, Inc. | Method for the crystallization of human serum albumin |
WO2004102151A2 (en) * | 2003-05-06 | 2004-11-25 | New Century Pharmaceuticals | Albumin binding sites for evaluating drug interactions and methods of evaluating or designing drugs based on therir albumin binding properties |
US20070043509A1 (en) * | 2003-11-03 | 2007-02-22 | Carter Daniel C | Albumin binding sites for evaluating drug interactions and methods of evaluating or designing drugs based on their albumin binding properties |
US7507552B1 (en) | 2004-04-16 | 2009-03-24 | Takeda San Diego, Inc. | Crystallization of histone deacetylase 2 |
US8176808B2 (en) * | 2007-09-13 | 2012-05-15 | Foster-Miller, Inc. | Robot arm assembly |
WO2013036829A1 (en) | 2011-09-09 | 2013-03-14 | Genentech, Inc | Treatment of th17 mediated inflammatory diseases |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL286954A (de) * | 1962-01-03 | |||
US3869436A (en) * | 1971-06-01 | 1975-03-04 | Statens Bakteriologiska Lab | Method for fractionating plasma proteins using peg and ion-exchangers |
US3790552A (en) * | 1972-03-16 | 1974-02-05 | Us Health | Method of removing hepatitis-associated antigen from a protein fraction using polyethylene glycol |
DK25877A (da) * | 1977-01-21 | 1978-08-15 | Nordisk Insulinlab | Fremgangsmaade til udvinding af renset albumin fra blodplasma |
US4197238A (en) * | 1977-04-12 | 1980-04-08 | The Green Cross Corporation | Method of preparation of human albumin using polyethylene glycol |
US4164496A (en) * | 1978-08-23 | 1979-08-14 | American National Red Cross | Preparation of albumin using PEG and EDTA |
US4489133A (en) * | 1982-11-16 | 1984-12-18 | The Board Of Trustees Of The Leland Stanford Jr. University | Two-dimensional crystallization technique |
US4668584A (en) * | 1985-12-23 | 1987-05-26 | General Electric Company | Method for forming 2-D crystals of proteins and macromolecules |
-
1987
- 1987-08-20 US US07/087,281 patent/US4833233A/en not_active Expired - Lifetime
-
1988
- 1988-08-19 AU AU21098/88A patent/AU604958B2/en not_active Ceased
- 1988-08-20 JP JP63205714A patent/JPH064677B2/ja not_active Expired - Fee Related
- 1988-08-22 CA CA000575341A patent/CA1336530C/en not_active Expired - Lifetime
- 1988-08-22 FR FR8811096A patent/FR2619567B1/fr not_active Expired - Fee Related
- 1988-09-05 EP EP88402228A patent/EP0357857B1/de not_active Expired - Lifetime
- 1988-09-05 DE DE8888402228T patent/DE3878239T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU604958B2 (en) | 1991-01-03 |
CA1336530C (en) | 1995-08-01 |
DE3878239D1 (de) | 1993-03-18 |
AU2109888A (en) | 1989-02-23 |
JPH064677B2 (ja) | 1994-01-19 |
EP0357857A1 (de) | 1990-03-14 |
FR2619567A1 (fr) | 1989-02-24 |
JPH01238599A (ja) | 1989-09-22 |
FR2619567B1 (fr) | 1995-02-17 |
US4833233A (en) | 1989-05-23 |
EP0357857B1 (de) | 1993-02-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3878239T2 (de) | Kristalle aus menschlichem serumalbumin und verfahren zu deren herstellung. | |
ATE166049T1 (de) | Phthalimidoperoxihexansäure, verfahren zu deren herstellung und deren verwendung | |
DE3879320D1 (de) | Copolyester und verfahren zu dessen herstellung. | |
DE3880515D1 (de) | Granuliertes mittel fuer wiederkaeuer und verfahren zu dessen herstellung. | |
DE3879613D1 (de) | Schnellrueckstellbares ptfe und verfahren zu dessen herstellung. | |
ATA125988A (de) | Pharmazeutische cefuroximaxetil-zusammensetzung und verfahren zu ihrer herstellung | |
DE68907876D1 (de) | Substanz dc 113 und verfahren zu ihrer herstellung. | |
DE3784612T2 (de) | Thermistor und verfahren zu seiner herstellung. | |
DE3868902D1 (de) | Suesswaren vorrichtung und verfahren zu deren herstellung. | |
DE68907057D1 (de) | Naehrstoffzusammensetzung und verfahren zu deren herstellung. | |
DE3867724D1 (de) | Modifiziertes feinpulveriges polytetrafluoraethylen und verfahren zu seiner herstellung. | |
DE3775614D1 (de) | Teilchenzaehler und verfahren zu dessen herstellung. | |
DE3878475D1 (de) | Organopolysiloxanemulsion und verfahren zu ihrer herstellung. | |
DE3882302T2 (de) | Filterkonstruktion und deren verfahren zur herstellung. | |
DE3879536D1 (de) | Supraleitender keramischer film und verfahren zu dessen herstellung. | |
ATE118220T1 (de) | Kristallines menschliches proinsulin und verfahren zu dessen herstellung. | |
DE3877709T2 (de) | Indan-derivate und verfahren zu deren herstellung. | |
DE3482258D1 (de) | 2,2-difluorpropionsaeurederivate und verfahren zu ihrer herstellung. | |
DE3751753D1 (de) | Kreuzstrom-filtrationsapparat und verfahren zu dessen herstellung | |
DE3886936D1 (de) | 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLEN 2-PGI-DERIVATE, VERFAHREN ZUR HERSTELLUNG UND DEREN VERWENDUNG. | |
DE3688153D1 (de) | Schuppenartige feine kristalle des zirkoniumoxydtyps und verfahren zu deren herstellung. | |
DE3867957D1 (de) | Modifiziertes polytetrafluoraethylen und verfahren zu seiner herstellung. | |
DE3777245D1 (de) | Protein und verfahren zu dessen herstellung. | |
DE3878578D1 (de) | Benzimidazol-derivate und verfahren zu ihrer herstellung. | |
DE3867392D1 (de) | Phenoxyalkancarbonsaeurederivate und verfahren zu ihrer herstellung. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |