DE50110742D1 - Mikrostrukturierte Plattform für die Untersuchung einer Flüssigkeit - Google Patents

Mikrostrukturierte Plattform für die Untersuchung einer Flüssigkeit

Info

Publication number
DE50110742D1
DE50110742D1 DE50110742T DE50110742T DE50110742D1 DE 50110742 D1 DE50110742 D1 DE 50110742D1 DE 50110742 T DE50110742 T DE 50110742T DE 50110742 T DE50110742 T DE 50110742T DE 50110742 D1 DE50110742 D1 DE 50110742D1
Authority
DE
Germany
Prior art keywords
structures
microstructured
channel system
flow
channel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE50110742T
Other languages
English (en)
Inventor
Dr Ralf-Peter Peters
Dr Holger Bartos
Christian Schoen
Dirk Osterloh
Dr Raimund Wyzgol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Microparts GmbH
Original Assignee
Boehringer Ingelheim Microparts GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Microparts GmbH filed Critical Boehringer Ingelheim Microparts GmbH
Application granted granted Critical
Publication of DE50110742D1 publication Critical patent/DE50110742D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0684Venting, avoiding backpressure, avoid gas bubbles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0418Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0688Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/08Regulating or influencing the flow resistance
    • B01L2400/084Passive control of flow resistance
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/08Regulating or influencing the flow resistance
    • B01L2400/084Passive control of flow resistance
    • B01L2400/086Passive control of flow resistance using baffles or other fixed flow obstructions
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer
DE50110742T 2000-10-25 2001-10-19 Mikrostrukturierte Plattform für die Untersuchung einer Flüssigkeit Expired - Lifetime DE50110742D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24324600P 2000-10-25 2000-10-25
US30582401P 2001-07-16 2001-07-16

Publications (1)

Publication Number Publication Date
DE50110742D1 true DE50110742D1 (de) 2006-09-28

Family

ID=26935699

Family Applications (1)

Application Number Title Priority Date Filing Date
DE50110742T Expired - Lifetime DE50110742D1 (de) 2000-10-25 2001-10-19 Mikrostrukturierte Plattform für die Untersuchung einer Flüssigkeit

Country Status (8)

Country Link
US (1) US6776965B2 (de)
EP (1) EP1201304B1 (de)
JP (1) JP4142280B2 (de)
KR (1) KR100876064B1 (de)
AT (1) ATE336298T1 (de)
CA (1) CA2359787C (de)
DE (1) DE50110742D1 (de)
DK (1) DK1201304T3 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014083799A1 (ja) * 2012-11-27 2014-06-05 日本電気株式会社 流体チップとその廃液方法

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6992901A (en) * 2000-06-19 2002-01-02 Caliper Techn Corp Methods and devices for enhancing bonded substrate yields and regulating temperature
US7141416B2 (en) * 2001-07-12 2006-11-28 Burstein Technologies, Inc. Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith
US6919058B2 (en) * 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
WO2003036298A2 (en) * 2001-10-25 2003-05-01 Exiqon A/S Closed substrate platforms suitable for analysis of biomolecules
US7459127B2 (en) * 2002-02-26 2008-12-02 Siemens Healthcare Diagnostics Inc. Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces
US20040042930A1 (en) * 2002-08-30 2004-03-04 Clemens Charles E. Reaction chamber with capillary lock for fluid positioning and retention
KR100444751B1 (ko) 2002-11-11 2004-08-16 한국전자통신연구원 표면장력에 의한 유체제어 소자
US7125711B2 (en) * 2002-12-19 2006-10-24 Bayer Healthcare Llc Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
US7435381B2 (en) * 2003-05-29 2008-10-14 Siemens Healthcare Diagnostics Inc. Packaging of microfluidic devices
US20040265172A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method and apparatus for entry and storage of specimens into a microfluidic device
US20050232821A1 (en) * 2003-09-19 2005-10-20 Carrillo Albert L High density plate filler
US7998435B2 (en) 2003-09-19 2011-08-16 Life Technologies Corporation High density plate filler
US9492820B2 (en) 2003-09-19 2016-11-15 Applied Biosystems, Llc High density plate filler
US7695688B2 (en) * 2003-09-19 2010-04-13 Applied Biosystems, Llc High density plate filler
US20070014694A1 (en) * 2003-09-19 2007-01-18 Beard Nigel P High density plate filler
US8277760B2 (en) 2003-09-19 2012-10-02 Applied Biosystems, Llc High density plate filler
DE10354806A1 (de) * 2003-11-21 2005-06-02 Boehringer Ingelheim Microparts Gmbh Probenträger
GB0327094D0 (en) * 2003-11-21 2003-12-24 Inverness Medical Switzerland Laminated device
DE10360220A1 (de) 2003-12-20 2005-07-21 Steag Microparts Gmbh Mikrostrukturierte Anordnung zur blasenfreien Befüllung zumindest eines Systems zur Ableitung von Flüssigkeiten, Vorrichtung mit einer solchen Anordnung und Befüllungsverfahren
US20050178218A1 (en) * 2004-01-28 2005-08-18 Jean Montagu Micro-volume blood sampling device
DE102004007567A1 (de) * 2004-02-17 2005-09-01 Boehringer Ingelheim Microparts Gmbh Mikrostrukturierte Plattform und Verfahren zum Handhaben einer Flüssigkeit
US7250260B2 (en) 2004-02-18 2007-07-31 Applera Corporation Multi-step bioassays on modular microfluidic application platforms
JP5168750B2 (ja) * 2004-03-29 2013-03-27 カシオ計算機株式会社 気化装置、反応装置及び発電装置
US7059352B2 (en) * 2004-03-31 2006-06-13 Lifescan Scotland Triggerable passive valve for use in controlling the flow of fluid
US7156117B2 (en) * 2004-03-31 2007-01-02 Lifescan Scotland Limited Method of controlling the movement of fluid through a microfluidic circuit using an array of triggerable passive valves
US7665303B2 (en) * 2004-03-31 2010-02-23 Lifescan Scotland, Ltd. Method of segregating a bolus of fluid using a pneumatic actuator in a fluid handling circuit
US20050217742A1 (en) * 2004-03-31 2005-10-06 Sebastian Bohm Microfluidic circuit including an array of triggerable passive valves
US20050220644A1 (en) * 2004-03-31 2005-10-06 Sebastian Bohm Pneumatic actuator for bolus generation in a fluid handling circuit
US20050220630A1 (en) * 2004-03-31 2005-10-06 Sebastian Bohm Method of using triggerable passive valves to control the flow of fluid
US20050249641A1 (en) * 2004-04-08 2005-11-10 Boehringer Ingelheim Microparts Gmbh Microstructured platform and method for manipulating a liquid
DE102004027422A1 (de) 2004-06-04 2005-12-29 Boehringer Ingelheim Microparts Gmbh Vorrichtung zur Aufnahme von Blut und Abtrennung von Blutbestandteilen
US8343074B2 (en) * 2004-06-30 2013-01-01 Lifescan Scotland Limited Fluid handling devices
US20060001551A1 (en) * 2004-06-30 2006-01-05 Ulrich Kraft Analyte monitoring system with wireless alarm
US20060000709A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Methods for modulation of flow in a flow pathway
US20060002817A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Flow modulation devices
EP1611955A1 (de) * 2004-07-01 2006-01-04 Agilent Technologies, Inc. Mikrofluidische Vorrichtung mit Filterkanal
DE102004033317A1 (de) 2004-07-09 2006-02-09 Roche Diagnostics Gmbh Analytisches Testelement
DE102004051573B4 (de) * 2004-10-22 2007-03-15 Yokogawa Electric Corporation, Musashino Verfahren zur Behandlung einer Abfallflüssigkeit in Chemischen Reaktions-Patronen und chemische Reaktions-Patrone, in der das Verfahren angewendet wird
CN100462710C (zh) * 2004-11-09 2009-02-18 横河电机株式会社 在盒中处理废液的方法及应用此方法的化学反应盒
TWI295730B (en) * 2004-11-25 2008-04-11 Ind Tech Res Inst Microfluidic chip for sample assay and method thereof
ATE503578T1 (de) 2005-01-27 2011-04-15 Boehringer Ingelheim Micropart Verwendung einer vorrichtung zur untersuchung von probenflüssigkeit
US20090111197A1 (en) * 2005-03-29 2009-04-30 Inverness Medical Switzerland Gmbh Hybrid device
DE102005016509A1 (de) * 2005-04-09 2006-10-12 Boehringer Ingelheim Microparts Gmbh Vorrichtung und Verfahren zur Untersuchung einer Probenflüssigkeit
WO2006108559A2 (de) * 2005-04-09 2006-10-19 Boehringer Ingelheim Microparts Gmbh Vorrichtung und verfahren zur untersuchung einer probenflüssigkeit
DE102005016508A1 (de) * 2005-04-09 2006-10-12 Boehringer Ingelheim Microparts Gmbh Vorrichtung und Verfahren zur Untersuchung einer Probenflüssigkeit
DE102005042601A1 (de) * 2005-04-09 2006-10-12 Boehringer Ingelheim Microparts Gmbh Vorrichtung und Verfahren zur Untersuchung einer Probenflüssigkeit
WO2006121510A2 (en) 2005-05-09 2006-11-16 Theranos, Inc. Point-of-care fluidic systems and uses thereof
US8288151B2 (en) * 2005-06-29 2012-10-16 Canon Kabushiki Kaisha Biochemical reaction cassette
JP4878200B2 (ja) * 2005-06-29 2012-02-15 キヤノン株式会社 生化学反応カセット
SE529643C3 (sv) * 2005-07-08 2007-11-06 Hemocue Ab En kuvett och en metod och ett verktyg för tillverkning därav
JP4671346B2 (ja) 2005-09-13 2011-04-13 キヤノン株式会社 液体充填性を向上させた生化学反応カセット
CN1987479A (zh) * 2005-12-23 2007-06-27 博奥生物有限公司 阻止液体在亲水性微细管内沿管壁楔角流动的微流体腔体
JP4177884B2 (ja) * 2006-03-09 2008-11-05 積水化学工業株式会社 マイクロ流体デバイスおよび微量液体希釈方法
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US20070280856A1 (en) * 2006-06-02 2007-12-06 Applera Corporation Devices and Methods for Controlling Bubble Formation in Microfluidic Devices
US20070280857A1 (en) * 2006-06-02 2007-12-06 Applera Corporation Devices and Methods for Positioning Dried Reagent In Microfluidic Devices
JP4859769B2 (ja) * 2006-06-30 2012-01-25 パナソニック株式会社 分析用パネル及びそれを用いた分析装置
US8158079B2 (en) * 2006-06-30 2012-04-17 Panasonic Corporation Panel for analysis and analyzer using the same
US8008034B2 (en) * 2006-10-13 2011-08-30 Theranos, Inc. Reducing optical interference in a fluidic device
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
JP5137551B2 (ja) 2006-12-28 2013-02-06 キヤノン株式会社 生化学反応カセット
EP1939136A3 (de) * 2006-12-29 2013-03-27 Corning Incorporated Druckfeste mikrofluidische Vorrichtungen mit hohem Durchsatz
WO2008098179A1 (en) * 2007-02-08 2008-08-14 Massachusetts Institute Of Technology In vitro microfluidic model of microcirculatory diseases, and methods of use thereof
GB0705418D0 (en) * 2007-03-21 2007-05-02 Vivacta Ltd Capillary
WO2008134363A1 (en) * 2007-04-25 2008-11-06 The Regents Of The University Of Michigan Tunable elastomeric nanochannels for nanofluidic manipulation
US7695976B2 (en) * 2007-08-29 2010-04-13 Plexera Bioscience, Llc Method for uniform analyte fluid delivery to microarrays
GB0802084D0 (en) * 2008-02-05 2008-03-12 Univ Dublin City Microfluidic device for assessing cell surface interactions
AU2009218752B2 (en) 2008-02-27 2014-07-10 Boehringer Ingelheim Microparts Gmbh Apparatus for the separation of plasma
WO2010115454A1 (en) 2009-04-06 2010-10-14 Trinean Nv Sample storage in microfluidics devices
EP2451575A2 (de) 2009-07-07 2012-05-16 Boehringer Ingelheim Microparts GmbH Plasmaabscheidungsreservoir
WO2011008415A2 (en) * 2009-07-17 2011-01-20 Ventana Medical Systems, Inc. Cover tile for treating a substrate with a fluid
EP2455162A1 (de) * 2010-10-29 2012-05-23 Roche Diagnostics GmbH Mikrofluidisches Element zur Analyse einer Probenflüssigkeit
PL3270141T3 (pl) 2011-03-08 2021-04-19 UNIVERSITé LAVAL Płynowe urządzenie centrypetalne
JP5116864B2 (ja) * 2011-06-15 2013-01-09 シャープ株式会社 マイクロ分析チップ
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9081001B2 (en) 2012-05-15 2015-07-14 Wellstat Diagnostics, Llc Diagnostic systems and instruments
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
DE102012021603A1 (de) 2012-06-28 2014-01-23 Philipp Comanns Strukturierung bzw. Anordnung von Oberflächen zum gerichteten Transport von Flüssigkeiten in Kapillaren
JP5549719B2 (ja) * 2012-09-20 2014-07-16 ブラザー工業株式会社 検査対象受体
US9962693B2 (en) 2012-12-13 2018-05-08 Koninklijke Philips N.V. Fluidic system with fluidic stop
US20160137963A1 (en) * 2013-06-28 2016-05-19 Danmarks Tekniske Universitet A Microfluidic Device with a Diffusion Barrier
JP6281945B2 (ja) * 2014-03-11 2018-02-21 国立研究開発法人産業技術総合研究所 多孔質媒体を利用したアッセイ装置
US11033896B2 (en) 2014-08-08 2021-06-15 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device with filtration flow control
US10071373B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device having flow constrictions
CA2965824A1 (en) * 2014-10-27 2016-05-06 Akonni Biosystems, Inc. Rotating sample positioning apparatus
USD799715S1 (en) 2015-10-23 2017-10-10 Gene POC, Inc. Fluidic centripetal device
EP3300801B1 (de) 2016-09-30 2019-09-04 Roche Diagniostics GmbH Mikrofluidische vorrichtung und verfahren zur herstellung davon
CN106944164B (zh) * 2017-03-08 2019-10-01 浙江大学 一种毛细驱动的芯片自动灌注系统
US11080848B2 (en) 2017-04-06 2021-08-03 Lucira Health, Inc. Image-based disease diagnostics using a mobile device
CN109985673A (zh) * 2019-04-01 2019-07-09 融智生物科技(青岛)有限公司 微流控芯片
CN113804658B (zh) * 2020-06-11 2023-06-06 京东方科技集团股份有限公司 微流控流道结构、检测系统及其使用方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486335A (en) * 1992-05-01 1996-01-23 Trustees Of The University Of Pennsylvania Analysis based on flow restriction
JP3076144B2 (ja) * 1992-05-01 2000-08-14 キヤノン株式会社 生体微量成分検査装置
US5637469A (en) * 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
WO1993022058A1 (en) * 1992-05-01 1993-11-11 Trustees Of The University Of Pennsylvania Polynucleotide amplification analysis using a microfabricated device
WO1994011489A1 (en) * 1992-11-06 1994-05-26 Biolog, Inc. Testing device for liquid and liquid suspended samples
US6315953B1 (en) * 1993-11-01 2001-11-13 Nanogen, Inc. Devices for molecular biological analysis and diagnostics including waveguides
JP4015188B2 (ja) * 1994-10-22 2007-11-28 ブリティッシュ ニュークリア フュエルズ パブリック リミティド カンパニー 不混和性流体間の拡散移動のための方法及び装置
JP4044163B2 (ja) * 1995-11-15 2008-02-06 アークレイ株式会社 液体検知方法および器具
US6709869B2 (en) * 1995-12-18 2004-03-23 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
CN1105914C (zh) * 1997-04-25 2003-04-16 卡钳技术有限公司 改进了通道几何结构的微型流体装置
BR9909249B1 (pt) * 1998-03-11 2009-12-01 suporte de amostras.
JP3258985B2 (ja) * 1999-08-09 2002-02-18 独立行政法人 食品総合研究所 白血球活性酸素産生量及び酸化ストレスの測定方法
US20020076727A1 (en) * 2000-08-03 2002-06-20 Cardone Michael H. Microarrays of functional biomolecules and uses therefor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014083799A1 (ja) * 2012-11-27 2014-06-05 日本電気株式会社 流体チップとその廃液方法

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CA2359787C (en) 2009-12-22
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CA2359787A1 (en) 2002-04-25
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ATE336298T1 (de) 2006-09-15
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