DE59201238D1 - Reaktionsdotierte brausesysteme. - Google Patents
Reaktionsdotierte brausesysteme.Info
- Publication number
- DE59201238D1 DE59201238D1 DE59201238T DE59201238T DE59201238D1 DE 59201238 D1 DE59201238 D1 DE 59201238D1 DE 59201238 T DE59201238 T DE 59201238T DE 59201238 T DE59201238 T DE 59201238T DE 59201238 D1 DE59201238 D1 DE 59201238D1
- Authority
- DE
- Germany
- Prior art keywords
- acid
- pct
- layer
- gas
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH194291 | 1991-07-01 | ||
PCT/EP1992/001421 WO1993000886A1 (de) | 1991-07-01 | 1992-06-24 | Reaktionsdotierte brausesysteme |
Publications (1)
Publication Number | Publication Date |
---|---|
DE59201238D1 true DE59201238D1 (de) | 1995-03-02 |
Family
ID=4222201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE59201238T Expired - Lifetime DE59201238D1 (de) | 1991-07-01 | 1992-06-24 | Reaktionsdotierte brausesysteme. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5415870A (de) |
EP (1) | EP0592484B1 (de) |
JP (1) | JP3517233B2 (de) |
AT (1) | ATE117199T1 (de) |
CA (1) | CA2112663C (de) |
DE (1) | DE59201238D1 (de) |
DK (1) | DK0592484T3 (de) |
ES (1) | ES2053411T3 (de) |
WO (1) | WO1993000886A1 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4027927A1 (de) * | 1990-09-04 | 1992-03-05 | Bayer Ag | Brausekomponente und verfahren zu ihrer herstellung |
US5503846A (en) * | 1993-03-17 | 1996-04-02 | Cima Labs, Inc. | Base coated acid particles and effervescent formulation incorporating same |
ES2091654T3 (es) * | 1993-04-15 | 1996-11-01 | Gergely Gerhard | Sistema efervescente que contiene un ingrediente activo farmaceutico sensible a alcalis y/o metales, y procedimiento para su produccion. |
ATE180164T1 (de) * | 1993-09-07 | 1999-06-15 | Gergely Gerhard | Brausemischung mit alkalisalzen oder lysinaten saurer, unlöslicher oder schwer löslicher wirkstoffe |
EP0670160B1 (de) * | 1994-03-01 | 1999-07-14 | Gerhard Dr. Gergely | Ein Brausesystem und einen Arzneiwirkstoff enthaltendes granuläres Produkt bzw. Tablette sowie Verfahren zu deren Herstellung |
DE670160T1 (de) * | 1994-03-01 | 1996-03-14 | Gerhard Gergely | Ein Brausesystem und einen Arzneiwirkstoff enthaltendes granuläres Produkt bzw. Tablette sowie Verfahren zu deren Herstellung. |
IL112779A (en) * | 1994-03-01 | 1999-11-30 | Gergely Gerhard | Granular product or tablet containing an efferescent system and an active pharmaceutical substance and its preparation |
US5824339A (en) * | 1995-09-08 | 1998-10-20 | Takeda Chemical Industries, Ltd | Effervescent composition and its production |
US6974595B1 (en) * | 1996-05-17 | 2005-12-13 | Proethic Pharmaceuticals, Inc. | Pharmaceutical compositions based on Diclofenae |
US6077539A (en) * | 1996-11-12 | 2000-06-20 | Pozen, Inc. | Treatment of migraine headache |
US5728401A (en) * | 1997-04-16 | 1998-03-17 | Ranbaxy Laboratories, Ltd. | Effervescent ranitidine formulations |
US6497900B2 (en) * | 1997-10-21 | 2002-12-24 | Gerhard Gergely | Effervescent base |
DE59706616D1 (de) * | 1997-10-27 | 2002-04-18 | Gergely Gerhard | Brausezubereitung mit Pflanzenextrakt |
WO1999027901A1 (fr) * | 1997-12-03 | 1999-06-10 | Kao Corporation | Preparation solide pour l'hygiene buccale |
US6235311B1 (en) * | 1998-03-18 | 2001-05-22 | Bristol-Myers Squibb Company | Pharmaceutical composition containing a combination of a statin and aspirin and method |
DE19814257A1 (de) * | 1998-03-31 | 1999-10-07 | Asta Medica Ag | Brauseformulierungen |
EP0962443B1 (de) * | 1998-06-03 | 2003-04-23 | Dr. Gergely & Co. | Mit Alkali- bzw. Erdalkali-Ionen dotierte Zitronensäure |
AT407111B (de) * | 1998-12-22 | 2000-12-27 | Gergely Dr & Co | Zucker- und/oder zuckeralkoholhältiges matrixmaterial und verfahren zu seiner herstellung |
GB9909801D0 (en) * | 1999-04-28 | 1999-06-23 | Btg Int Ltd | Ultrasound detectable instrument |
US6766753B2 (en) * | 2001-03-20 | 2004-07-27 | Hank E Pierson | Pre-feeder for a main sail |
EP1490024B1 (de) | 2002-03-06 | 2012-01-18 | EffRx Pharmaceuticals SA | Brausetabletten, enthaltend alendronat |
US7488496B2 (en) * | 2002-03-06 | 2009-02-10 | Christer Rosen | Effervescent compositions comprising bisphosphonates and methods related thereto |
DK1638485T3 (da) * | 2003-06-20 | 2011-05-02 | Intrinsic Therapeutics Inc | Indretning til levering af et implantat gennem en ringformet defekt i en intervertebralskive |
US8431171B2 (en) * | 2006-07-12 | 2013-04-30 | Purac Biochem B.V. | Partially neutralized acid coated food-grade particles |
BRPI0714423B1 (pt) | 2006-07-12 | 2016-10-04 | Purac Biochem Bv | partícula grau alimentício revestida com ácido parcialmente neutralizado, produto alimentício ou bebida, método para preparação da referida partícula e uso de ácido policarboxílico |
US8778398B2 (en) | 2008-11-04 | 2014-07-15 | Jazz Pharmaceuticals, Inc. | Immediate release formulations and dosage forms of gamma-hydroxybutyrate |
TR200900881A2 (tr) * | 2009-02-05 | 2010-08-23 | Bi̇lgi̇ç Mahmut | Tadı ve kokusu maskelenmiş stabil farmasötik bileşimler |
EP2549987A4 (de) | 2010-03-24 | 2015-01-21 | Jazz Pharmaceuticals Inc | Dosierungsformen mit gesteuerter freisetzung für hochdosierte, wasserlösliche und hygroskopische arzneimittel |
MX340591B (es) * | 2010-05-04 | 2016-07-15 | Jazz Pharmaceuticals Inc * | Formulaciones de liberacion inmediata y formas de dosis de gamma-hidroxibutirato. |
US9592195B2 (en) * | 2010-12-06 | 2017-03-14 | Effrx Pharmaceuticals Sa | Stable effervescent bisphosphonate formulations with rapid solubilization characteristics |
WO2013115746A1 (en) * | 2012-01-31 | 2013-08-08 | Mahmut Bilgic | A production method for (effervescent) pharmaceutical compositions comprising an alpha - glucosidase inhibitor (miglitol) and metformin |
WO2014065890A1 (en) * | 2012-10-25 | 2014-05-01 | Otc Nutrition Llc | Fast dissolving solid calcium mineral supplement compositions and process of making |
JP5935172B2 (ja) * | 2013-01-22 | 2016-06-15 | 株式会社東洋新薬 | 発泡性皮膚外用剤 |
US20150025025A1 (en) * | 2013-07-19 | 2015-01-22 | Ricky McCullough | Immuno-modulators for treating functional epithelial syndromes |
JP6627485B2 (ja) * | 2015-01-28 | 2020-01-08 | ライオン株式会社 | ゲル組成物及びその製造方法 |
US10398662B1 (en) | 2015-02-18 | 2019-09-03 | Jazz Pharma Ireland Limited | GHB formulation and method for its manufacture |
US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
US20180263936A1 (en) | 2017-03-17 | 2018-09-20 | Jazz Pharmaceuticals Ireland Limited | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
EP3883549A1 (de) | 2018-11-19 | 2021-09-29 | Jazz Pharmaceuticals Ireland Limited | Alkoholresistente arzneimittelformulierungen |
JP2022522270A (ja) | 2019-03-01 | 2022-04-15 | フラメル アイルランド リミテッド | 食事摂取状態における改善された薬物動態を有するガンマ-ヒドロキシ酪酸塩組成物 |
JP2021014431A (ja) * | 2019-07-12 | 2021-02-12 | ライオン株式会社 | 粉体組成物、粉体組成物を含有する内服固形製剤及びその製造方法 |
CN111184694A (zh) * | 2020-01-19 | 2020-05-22 | 广东青云山药业有限公司 | 一种口腔速溶颗粒的制备方法 |
US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2211485A (en) * | 1940-08-13 | Effervescent acetyl salicylic acid | ||
US3345265A (en) * | 1963-10-09 | 1967-10-03 | Kendall & Co | Multiple layer tablet with calcium salt central core separated from soluble fluoride outer coating |
US3887700A (en) * | 1969-11-28 | 1975-06-03 | Aspro Nicholas Ltd | Analgesic formulations |
US4127645A (en) * | 1976-05-21 | 1978-11-28 | Life Savers, Inc. | Effervescent tablet and method |
AT374348B (de) * | 1980-07-01 | 1984-04-10 | Gergely Gerhard | Verfahren zur herstellung von gewuenschtenfalls zu brausetabletten verarbeitbaren brausegranulaten |
JPS5756434A (en) * | 1980-09-22 | 1982-04-05 | Kao Corp | Stabilized foamable composition |
US4678661A (en) * | 1983-09-28 | 1987-07-07 | Gerhard Gergely | Effervescent composition and method of making same |
FR2593065B1 (fr) * | 1986-01-22 | 1988-09-09 | Smith Kline French Lab | Couples effervescents, compositions effervescentes d'antagonistes h2 de l'histamine les contenant et leur preparation. |
DE3627475A1 (de) * | 1986-06-26 | 1988-01-14 | Gergely Gerhard | Verfahren zum herstellen eines brausegranulates, danach hergestelltes brausegranulat sowie dessen verwendung |
US5064656A (en) * | 1989-11-14 | 1991-11-12 | Dr. Gergely & Co. | Uncoated pharmaceutical reaction tablet |
-
1992
- 1992-06-24 AT AT92912980T patent/ATE117199T1/de active
- 1992-06-24 US US08/170,262 patent/US5415870A/en not_active Expired - Lifetime
- 1992-06-24 DK DK92912980.7T patent/DK0592484T3/da not_active Application Discontinuation
- 1992-06-24 DE DE59201238T patent/DE59201238D1/de not_active Expired - Lifetime
- 1992-06-24 CA CA002112663A patent/CA2112663C/en not_active Expired - Fee Related
- 1992-06-24 ES ES92912980T patent/ES2053411T3/es not_active Expired - Lifetime
- 1992-06-24 JP JP50191693A patent/JP3517233B2/ja not_active Expired - Fee Related
- 1992-06-24 WO PCT/EP1992/001421 patent/WO1993000886A1/de active IP Right Grant
- 1992-06-24 EP EP92912980A patent/EP0592484B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2053411T1 (es) | 1994-08-01 |
DK0592484T3 (da) | 1995-06-12 |
ATE117199T1 (de) | 1995-02-15 |
JP3517233B2 (ja) | 2004-04-12 |
EP0592484B1 (de) | 1995-01-18 |
CA2112663A1 (en) | 1993-01-21 |
JPH06508839A (ja) | 1994-10-06 |
EP0592484A1 (de) | 1994-04-20 |
US5415870A (en) | 1995-05-16 |
CA2112663C (en) | 2002-04-23 |
ES2053411T3 (es) | 1995-05-01 |
WO1993000886A1 (de) | 1993-01-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
R071 | Expiry of right |
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