DE60009904D1 - Bakteriochlorine und bakteriopurpurine und deren verwendung zur photodynamischen therapie von tumoren sowie ein verfahren zu deren herstellung - Google Patents
Bakteriochlorine und bakteriopurpurine und deren verwendung zur photodynamischen therapie von tumoren sowie ein verfahren zu deren herstellungInfo
- Publication number
- DE60009904D1 DE60009904D1 DE60009904T DE60009904T DE60009904D1 DE 60009904 D1 DE60009904 D1 DE 60009904D1 DE 60009904 T DE60009904 T DE 60009904T DE 60009904 T DE60009904 T DE 60009904T DE 60009904 D1 DE60009904 D1 DE 60009904D1
- Authority
- DE
- Germany
- Prior art keywords
- bacteriochlorins
- bacteriopurpurins
- photodynamic therapy
- methods
- bacteriopurpurine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US320731 | 1999-05-27 | ||
US09/320,731 US6376483B1 (en) | 1999-05-27 | 1999-05-27 | Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production |
PCT/US2000/013999 WO2000073308A2 (en) | 1999-05-27 | 2000-05-23 | Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60009904D1 true DE60009904D1 (de) | 2004-05-19 |
DE60009904T2 DE60009904T2 (de) | 2005-04-07 |
Family
ID=23247659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60009904T Expired - Fee Related DE60009904T2 (de) | 1999-05-27 | 2000-05-23 | Bakteriochlorine und bakteriopurpurine und deren verwendung zur photodynamischen therapie von tumoren sowie ein verfahren zu deren herstellung |
Country Status (7)
Country | Link |
---|---|
US (1) | US6376483B1 (de) |
EP (1) | EP1189906B1 (de) |
AT (1) | ATE264331T1 (de) |
AU (1) | AU5151900A (de) |
CA (1) | CA2372239A1 (de) |
DE (1) | DE60009904T2 (de) |
WO (1) | WO2000073308A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648485A (en) * | 1994-10-26 | 1997-07-15 | University Of British Columbia | β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins |
US6559374B2 (en) * | 2000-07-21 | 2003-05-06 | North Carolina State University | Trans beta substituted chlorins and methods of making and using the same |
AU2003230808A1 (en) * | 2002-04-05 | 2003-10-27 | Candela Corporation | High fluence rate activation of photosensitizers for dermatological applications |
US20050008687A1 (en) * | 2003-07-07 | 2005-01-13 | Makoto Yuasa | Metal-porphyrin-complex-embedded liposomes, production process thereof, and medicines making use of the same |
CA2437638A1 (en) * | 2003-08-20 | 2005-02-20 | John Robert North | Photodynamic therapy |
US7501507B2 (en) * | 2004-06-14 | 2009-03-10 | North Carolina State University | Route to formyl-porphyrins |
EP1848778B1 (de) * | 2005-02-18 | 2013-04-10 | North Carolina State University | Neusynthese von bakteriochlorinen |
GB0819594D0 (en) | 2008-10-24 | 2008-12-03 | Univ Coimbrra | Process |
WO2010132515A1 (en) | 2009-05-12 | 2010-11-18 | Mallinckrodt Inc. | Compounds containing acyclic n-n bonds for phototherapy |
WO2010132554A2 (en) | 2009-05-12 | 2010-11-18 | Mallinckrodt Inc. | Diaza heterocyclic compounds for phototherapy |
WO2018035281A1 (en) * | 2016-08-17 | 2018-02-22 | North Carolina State University | Northern-southern route to synthesis of bacteriochlorins |
EP3565818A4 (de) * | 2017-02-03 | 2021-03-10 | NIRvana Sciences Inc. | Hydroporphyrine zur photoakustischen bildgebung |
US11904026B2 (en) | 2017-02-03 | 2024-02-20 | Nirvana Sciences Inc. | Metallohydroporphyrins for photoacoustic imaging |
JP2024503292A (ja) * | 2021-01-04 | 2024-01-25 | ニルバナ サイエンシーズ インク. | 光音響イメージング用のメタロヒドロポルフィリン |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4649151A (en) | 1982-09-27 | 1987-03-10 | Health Research, Inc. | Drugs comprising porphyrins |
US5216012A (en) | 1986-01-02 | 1993-06-01 | University Of Toledo | Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions |
US5051415A (en) | 1986-01-02 | 1991-09-24 | The University Of Toledo | Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions |
US5534506A (en) | 1986-01-02 | 1996-07-09 | University Of Toledo | Use of purpurins, chlorins and purpurin- and chlorin-containing compositions |
US5049557A (en) | 1986-05-13 | 1991-09-17 | Chai-Tech Corporation | Metallo-organic salt compounds and pharmaceutical uses thereof |
US4877872A (en) | 1986-06-24 | 1989-10-31 | The University Of Toledo | Production and use of dimers of hematoporophyrin, purpurins, chlorines and purpurin- and chlorin-complexes |
US5171749A (en) | 1987-01-20 | 1992-12-15 | University Of British Columbia | Wavelength-specific cytotoxic agents |
US5283255A (en) | 1987-01-20 | 1994-02-01 | The University Of British Columbia | Wavelength-specific cytotoxic agents |
US5109129A (en) | 1989-09-29 | 1992-04-28 | The University Of Toledo, Medical College Of Ohio | Porphyrin derivatives |
US5198460A (en) | 1988-07-20 | 1993-03-30 | Health Research Inc. | Pyropheophorbides and their use in photodynamic therapy |
US5002962A (en) | 1988-07-20 | 1991-03-26 | Health Research, Inc. | Photosensitizing agents |
US5177073A (en) | 1988-09-30 | 1993-01-05 | Baylor Research Institute | Therapeutic compositions derived from photoactive compounds |
US5236915A (en) | 1990-05-31 | 1993-08-17 | Health Research, Inc. | Meso poly(4-sulfonatophenyl) porphines as MRI image enhancing agents |
US5272056A (en) | 1991-01-03 | 1993-12-21 | The Research Foundation Of State University Of New York | Modification of DNA and oligonucleotides using metal complexes of polyaza ligands |
US5563262A (en) | 1991-03-28 | 1996-10-08 | University Of Toledo | Diels alder adducts of vinyl porphyrins |
US5212300A (en) | 1991-09-12 | 1993-05-18 | Sun Company, Inc. (R&M) | Cyano- and polycyanometallo-porphyrins as catalysts for alkane oxidation |
JP3598306B2 (ja) | 1992-09-21 | 2004-12-08 | キューエルティ インク. | 血液における感光剤の皮膚を通しての生体内活性化 |
US5405957A (en) | 1992-10-30 | 1995-04-11 | The University Of British Columbia | Wavelength-specific photosensitive compounds and expanded porphyrin-like compounds and methods of use |
US5368841A (en) | 1993-02-11 | 1994-11-29 | The General Hospital Corporation | Photodynamic therapy for the destruction of the synovium in the treatment of rheumatoid arthritis and the inflammatory arthritides |
US5591847A (en) | 1994-05-23 | 1997-01-07 | Health Research, Inc. | Long wavelength absorbing photosensitizers related to purpurin-18, bacteriopurpurin-18 and related compounds with imide linkages |
US5563132A (en) | 1994-06-21 | 1996-10-08 | Bodaness; Richard S. | Two-step cancer treatment method |
US5648485A (en) | 1994-10-26 | 1997-07-15 | University Of British Columbia | β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins |
US5770730A (en) | 1996-03-08 | 1998-06-23 | Health Research, Inc. | Synthesis of carbodimide analogs of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer |
-
1999
- 1999-05-27 US US09/320,731 patent/US6376483B1/en not_active Expired - Fee Related
-
2000
- 2000-05-23 WO PCT/US2000/013999 patent/WO2000073308A2/en active IP Right Grant
- 2000-05-23 CA CA002372239A patent/CA2372239A1/en not_active Abandoned
- 2000-05-23 EP EP00936158A patent/EP1189906B1/de not_active Expired - Lifetime
- 2000-05-23 DE DE60009904T patent/DE60009904T2/de not_active Expired - Fee Related
- 2000-05-23 AT AT00936158T patent/ATE264331T1/de not_active IP Right Cessation
- 2000-05-23 AU AU51519/00A patent/AU5151900A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2372239A1 (en) | 2000-12-07 |
ATE264331T1 (de) | 2004-04-15 |
US6376483B1 (en) | 2002-04-23 |
EP1189906B1 (de) | 2004-04-14 |
DE60009904T2 (de) | 2005-04-07 |
WO2000073308A3 (en) | 2001-04-19 |
AU5151900A (en) | 2000-12-18 |
WO2000073308A2 (en) | 2000-12-07 |
EP1189906A2 (de) | 2002-03-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |