DE60027698D1 - Lasttragendes osteoimplantat und verfahren zu seiner herstellung - Google Patents

Lasttragendes osteoimplantat und verfahren zu seiner herstellung

Info

Publication number
DE60027698D1
DE60027698D1 DE60027698T DE60027698T DE60027698D1 DE 60027698 D1 DE60027698 D1 DE 60027698D1 DE 60027698 T DE60027698 T DE 60027698T DE 60027698 T DE60027698 T DE 60027698T DE 60027698 D1 DE60027698 D1 DE 60027698D1
Authority
DE
Germany
Prior art keywords
osteoimplantate
loading
load
production
loading osteoimplantate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60027698T
Other languages
English (en)
Other versions
DE60027698T2 (de
Inventor
M Boyce
A Shimp
Albert Manrique
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osteotech Inc
Original Assignee
Osteotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osteotech Inc filed Critical Osteotech Inc
Application granted granted Critical
Publication of DE60027698D1 publication Critical patent/DE60027698D1/de
Publication of DE60027698T2 publication Critical patent/DE60027698T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/32Joints for the hip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4644Preparation of bone graft, bone plugs or bone dowels, e.g. grinding or milling bone material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608Bone, e.g. demineralised bone matrix [DBM], bone powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645Connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843Connective tissue
    • A61L27/3847Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005Ingredients of undetermined constitution or reaction products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
DE60027698T 1999-02-23 2000-02-22 Lasttragendes osteoimplantat und verfahren zu seiner herstellung Expired - Lifetime DE60027698T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US256447 1988-10-12
US09/256,447 US6294187B1 (en) 1999-02-23 1999-02-23 Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same
PCT/US2000/004408 WO2000050102A1 (en) 1999-02-23 2000-02-22 Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same

Publications (2)

Publication Number Publication Date
DE60027698D1 true DE60027698D1 (de) 2006-06-08
DE60027698T2 DE60027698T2 (de) 2007-04-26

Family

ID=22972272

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60027698T Expired - Lifetime DE60027698T2 (de) 1999-02-23 2000-02-22 Lasttragendes osteoimplantat und verfahren zu seiner herstellung

Country Status (10)

Country Link
US (2) US6294187B1 (de)
EP (1) EP1152777B1 (de)
JP (1) JP4658331B2 (de)
KR (1) KR100754814B1 (de)
AU (1) AU758828B2 (de)
CA (1) CA2363153C (de)
DE (1) DE60027698T2 (de)
ES (1) ES2261191T3 (de)
TR (1) TR200102480T2 (de)
WO (1) WO2000050102A1 (de)

Families Citing this family (408)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7019192B2 (en) * 1998-02-27 2006-03-28 Musculoskeletal Transplant Foundation Composition for filling bone defects
US6998135B1 (en) * 1998-02-27 2006-02-14 Musculoskeletal Transplant Foundation Demineralized corticocancellous bone sheet
US7045141B2 (en) 1998-02-27 2006-05-16 Musculoskeletal Transplant Foundation Allograft bone composition having a gelatin binder
US20080077251A1 (en) * 1999-06-07 2008-03-27 Chen Silvia S Cleaning and devitalization of cartilage
US6293970B1 (en) 1998-06-30 2001-09-25 Lifenet Plasticized bone and soft tissue grafts and methods of making and using same
US20100030340A1 (en) * 1998-06-30 2010-02-04 Wolfinbarger Jr Lloyd Plasticized Grafts and Methods of Making and Using Same
US8563232B2 (en) 2000-09-12 2013-10-22 Lifenet Health Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced
US20030114936A1 (en) * 1998-10-12 2003-06-19 Therics, Inc. Complex three-dimensional composite scaffold resistant to delimination
US6025538A (en) * 1998-11-20 2000-02-15 Musculoskeletal Transplant Foundation Compound bone structure fabricated from allograft tissue
US6383519B1 (en) * 1999-01-26 2002-05-07 Vita Special Purpose Corporation Inorganic shaped bodies and methods for their production and use
US8133421B2 (en) * 1999-02-23 2012-03-13 Warsaw Orthopedic, Inc. Methods of making shaped load-bearing osteoimplant
US6294187B1 (en) * 1999-02-23 2001-09-25 Osteotech, Inc. Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same
US20070233272A1 (en) * 1999-02-23 2007-10-04 Boyce Todd M Shaped load-bearing osteoimplant and methods of making same
US6241770B1 (en) * 1999-03-05 2001-06-05 Gary K. Michelson Interbody spinal fusion implant having an anatomically conformed trailing end
WO2000054821A1 (en) * 1999-03-16 2000-09-21 Regeneration Technologies, Inc. Molded implants for orthopedic applications
US6767928B1 (en) * 1999-03-19 2004-07-27 The Regents Of The University Of Michigan Mineralization and biological modification of biomaterial surfaces
US6558422B1 (en) * 1999-03-26 2003-05-06 University Of Washington Structures having coated indentations
CA2363562C (en) 1999-05-05 2010-08-03 Gary Karlin Michelson Nested interbody spinal fusion implants
US6258124B1 (en) * 1999-05-10 2001-07-10 C. R. Bard, Inc. Prosthetic repair fabric
US7270705B2 (en) * 1999-07-14 2007-09-18 Jiin-Huey Chern Lin Method of increasing working time of tetracalcium phosphate cement paste
US7094282B2 (en) * 2000-07-13 2006-08-22 Calcitec, Inc. Calcium phosphate cement, use and preparation thereof
US6840995B2 (en) * 1999-07-14 2005-01-11 Calcitec, Inc. Process for producing fast-setting, bioresorbable calcium phosphate cements
US7169373B2 (en) * 1999-07-14 2007-01-30 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface and process for preparing the same
US6960249B2 (en) * 1999-07-14 2005-11-01 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface
US6458162B1 (en) 1999-08-13 2002-10-01 Vita Special Purpose Corporation Composite shaped bodies and methods for their production and use
AU7403100A (en) 1999-08-20 2001-03-19 Peter Metz-Stavenhagen Vertebral column segment
US20050059953A1 (en) 1999-09-03 2005-03-17 Lifenet Apparatus for demineralizing osteoinductive bone
US6830763B2 (en) * 1999-09-03 2004-12-14 Lifenet Continuous acidification demineralization process for producing osteoinductive bone; and osteoinductive bone produced thereby
KR100689250B1 (ko) * 1999-09-30 2007-03-08 가켄 세야쿠 가부시키가이샤 흉골 절개 후 흉골의 치유를 증진시키는 방법
US20030228288A1 (en) 1999-10-15 2003-12-11 Scarborough Nelson L. Volume maintaining osteoinductive/osteoconductive compositions
US20010032017A1 (en) 1999-12-30 2001-10-18 Alfaro Arthur A. Intervertebral implants
US7635390B1 (en) 2000-01-14 2009-12-22 Marctec, Llc Joint replacement component having a modular articulating surface
US6702821B2 (en) 2000-01-14 2004-03-09 The Bonutti 2003 Trust A Instrumentation for minimally invasive joint replacement and methods for using same
WO2001068004A2 (en) * 2000-03-10 2001-09-20 Sdgi Holdings, Inc. Synthetic reinforced interbody fusion implants
AR027685A1 (es) 2000-03-22 2003-04-09 Synthes Ag Forma de tejido y metodo para realizarlo
US6350283B1 (en) 2000-04-19 2002-02-26 Gary K. Michelson Bone hemi-lumbar interbody spinal implant having an asymmetrical leading end and method of installation thereof
US7462195B1 (en) 2000-04-19 2008-12-09 Warsaw Orthopedic, Inc. Artificial lumbar interbody spinal implant having an asymmetrical leading end
AU2001274821A1 (en) * 2000-06-13 2001-12-24 Gary K. Michelson Manufactured major long bone ring implant shaped to conform to a prepared intervertebral implantation space
US20020111680A1 (en) * 2000-06-13 2002-08-15 Michelson Gary K. Ratcheted bone dowel
DE60117984T8 (de) * 2000-06-29 2007-06-14 Bio Syntech Canada Inc., Laval Zusammensetzung und verfahren zur reparatur und regenerierung von knorpel und anderen geweben
US6863694B1 (en) 2000-07-03 2005-03-08 Osteotech, Inc. Osteogenic implants derived from bone
US6332779B1 (en) 2000-07-03 2001-12-25 Osteotech, Inc. Method of hard tissue repair
DE60101967T2 (de) * 2000-07-03 2004-07-22 Osteotech, Inc. Knochenbildendes implantat aus knochen
US7182928B2 (en) * 2000-07-13 2007-02-27 Calcitec, Inc. Calcium phosphate cements made from (TTCP) with surface whiskers and process for preparing same
US7001551B2 (en) * 2000-07-13 2006-02-21 Allograft Research Technologies, Inc. Method of forming a composite bone material implant
US7156915B2 (en) * 2000-07-13 2007-01-02 Calcitec, Inc. Tetracalcium phosphate (TTCP) with surface whiskers and method of making same
US9387094B2 (en) * 2000-07-19 2016-07-12 Warsaw Orthopedic, Inc. Osteoimplant and method of making same
EP1301222B1 (de) * 2000-07-19 2005-12-14 Osteotech, Inc. Osteoimplantat und verfahren zu seiner herstellung
US6638312B2 (en) * 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) * 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US6739112B1 (en) * 2000-08-21 2004-05-25 Nu Vasive, Inc. Bone allograft packaging system
US20050064041A1 (en) * 2000-09-05 2005-03-24 Lifenet Continuous acidification demineralization process for producing osteoinductive bone; and osteoinductive bone produced thereby
ES2317933T3 (es) 2000-09-19 2009-05-01 Eduardo Anitua Aldecoa Metodo de tratamiento superficial de implantes o protesis realizados en titanio.
EP1576938B1 (de) 2000-10-11 2006-08-02 Michael D. Mason Wirbelfusionsvorrichtung
JP2004512870A (ja) * 2000-10-13 2004-04-30 オステオテック インコーポレーテッド 体積維持骨誘導性/骨伝導性組成物
US20030120274A1 (en) * 2000-10-20 2003-06-26 Morris John W. Implant retaining device
EP2085055B1 (de) * 2000-10-24 2012-06-06 Warsaw Orthopedic, Inc. Wirbelfusionsvorrichtungen
WO2002036049A2 (en) 2000-11-03 2002-05-10 Osteotech, Inc. Spinal intervertebral implant and method of making
US6692498B1 (en) * 2000-11-27 2004-02-17 Linvatec Corporation Bioabsorbable, osteopromoting fixation plate
AU2002245092A1 (en) * 2000-12-08 2002-07-30 Todd M. Boyce Implant for orthopedic applications
US7323193B2 (en) 2001-12-14 2008-01-29 Osteotech, Inc. Method of making demineralized bone particles
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7931692B2 (en) 2001-02-14 2011-04-26 Osteotech, Inc. Implant derived from bone
US20030045935A1 (en) * 2001-02-28 2003-03-06 Angelucci Christopher M. Laminoplasty implants and methods of use
US6855169B2 (en) * 2001-02-28 2005-02-15 Synthes (Usa) Demineralized bone-derived implants
IL141813A (en) * 2001-03-05 2010-04-15 Hadasit Med Res Service Mixture comprising bone marrow cells together with demineralized and/or mineralized bone matrix and uses thereof in the preparation of compositions for the treatment of hematopoietic dusirders
US6890355B2 (en) 2001-04-02 2005-05-10 Gary K. Michelson Artificial contoured spinal fusion implants made of a material other than bone
US6989031B2 (en) 2001-04-02 2006-01-24 Sdgi Holdings, Inc. Hemi-interbody spinal implant manufactured from a major long bone ring or a bone composite
US6749636B2 (en) * 2001-04-02 2004-06-15 Gary K. Michelson Contoured spinal fusion implants made of bone or a bone composite material
CA2442855A1 (en) * 2001-04-12 2002-10-24 Therics, Inc. Method and apparatus for engineered regenerative biostructures
DE10126085A1 (de) * 2001-05-29 2002-12-05 Tutogen Medical Gmbh Knochenimplantat
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
AU2002316696B2 (en) * 2001-07-16 2007-08-30 Depuy Products, Inc. Cartilage repair and regeneration scaffold and method
WO2003007790A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
WO2003007839A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Devices form naturally occurring biologically derived
EP1416888A4 (de) 2001-07-16 2007-04-25 Depuy Products Inc Vorrichtung und verfahren zur regeneration des meniskus
US8025896B2 (en) 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
US7618937B2 (en) * 2001-07-20 2009-11-17 Northwestern University Peptidomimetic polymers for antifouling surfaces
US8815793B2 (en) * 2001-07-20 2014-08-26 Northwestern University Polymeric compositions and related methods of use
US7858679B2 (en) * 2001-07-20 2010-12-28 Northwestern University Polymeric compositions and related methods of use
WO2003013623A1 (en) * 2001-08-10 2003-02-20 Osteotech, Inc. Bone plating system and method of use
US7892288B2 (en) 2001-08-27 2011-02-22 Zimmer Technology, Inc. Femoral augments for use with knee joint prosthesis
US20030065397A1 (en) 2001-08-27 2003-04-03 Hanssen Arlen D. Prosthetic implant support structure
US20040162619A1 (en) 2001-08-27 2004-08-19 Zimmer Technology, Inc. Tibial augments for use with knee joint prostheses, method of implanting the tibial augment, and associated tools
US7708741B1 (en) 2001-08-28 2010-05-04 Marctec, Llc Method of preparing bones for knee replacement surgery
US6635087B2 (en) 2001-08-29 2003-10-21 Christopher M. Angelucci Laminoplasty implants and methods of use
EP1434608B1 (de) * 2001-10-12 2018-08-22 Warsaw Orthopedic, Inc. Verbessertes knochenimplantat
US20030139812A1 (en) * 2001-11-09 2003-07-24 Javier Garcia Spinal implant
US6855167B2 (en) 2001-12-05 2005-02-15 Osteotech, Inc. Spinal intervertebral implant, interconnections for such implant and processes for making
WO2003055933A1 (en) * 2001-12-21 2003-07-10 Isotis Orthobiologics, Inc. End-capped polyalkylene glycols and compositions containing such compounds
US7205337B2 (en) * 2001-12-21 2007-04-17 Isotis Orthobiologics, Inc. End-capped polymers and compositions containing such compounds
JP2005516972A (ja) * 2002-01-22 2005-06-09 ファイザー・インク 血栓疾患の治療のためのtafi−a阻害剤として使用される3−(イミダゾリル)−2−アミノプロピオン酸
EP1344538A1 (de) * 2002-03-14 2003-09-17 Degradable Solutions AG Poröses und bioabbaubares Implantatmaterial und Verfahren zu seiner Herstellung
US20040137032A1 (en) * 2002-03-15 2004-07-15 Wang Francis W. Combinations of calcium phosphates, bone growth factors, and pore-forming additives as osteoconductive and osteoinductive composite bone grafts
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US20030216777A1 (en) * 2002-05-16 2003-11-20 Yin-Chun Tien Method of enhancing healing of interfacial gap between bone and tendon or ligament
US20060204544A1 (en) * 2002-05-20 2006-09-14 Musculoskeletal Transplant Foundation Allograft bone composition having a gelatin binder
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
WO2003099412A1 (en) 2002-05-24 2003-12-04 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
AU2003238805A1 (en) * 2002-05-30 2003-12-19 Osteotech, Inc. Method and apparatus for machining a surgical implant
EP1369095A3 (de) * 2002-06-04 2004-01-14 MTF MediTech Franken GmbH Verfahren und Vorrichtung zum Befeuchten eines medizinischen Implantates oder Transplantates
ES2311568T3 (es) 2002-06-04 2009-02-16 Mtf Meditech Franken Gmbh Procedimiento y dispositivo para humectar material de implante medico no biologico.
NZ550755A (en) * 2002-06-10 2009-06-26 Keratec Ltd Orthopaedic materials derived from keratin
JP4179495B2 (ja) * 2002-06-12 2008-11-12 松崎 浩巳 骨補填材
US7166133B2 (en) * 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US8911831B2 (en) * 2002-07-19 2014-12-16 Northwestern University Surface independent, surface-modifying, multifunctional coatings and applications thereof
US20080171012A1 (en) * 2007-01-11 2008-07-17 Phillip Messersmith Fouling Resistant Coatings and Methods of Making Same
AU2002950443A0 (en) * 2002-07-26 2002-09-12 Graeme Brazenor Pty Limited Spinal implant
EP2392359A3 (de) * 2002-08-12 2012-03-07 Warsaw Orthopedic, Inc. Synthese eines Knochen-Polymer-Verbundwerkstoffs
US7270813B2 (en) * 2002-10-08 2007-09-18 Osteotech, Inc. Coupling agents for orthopedic biomaterials
US7323011B2 (en) 2002-10-18 2008-01-29 Musculoskeletal Transplant Foundation Cortical and cancellous allograft cervical fusion block
US7682392B2 (en) * 2002-10-30 2010-03-23 Depuy Spine, Inc. Regenerative implants for stabilizing the spine and devices for attachment of said implants
US7582309B2 (en) * 2002-11-15 2009-09-01 Etex Corporation Cohesive demineralized bone compositions
US6761739B2 (en) 2002-11-25 2004-07-13 Musculoskeletal Transplant Foundation Cortical and cancellous allograft spacer
US20060216494A1 (en) * 2002-11-25 2006-09-28 Helga Furedi-Milhofer Organic-inorganic nanocomposite coatings for implant materials and methods of preparation thereof
WO2004053112A1 (en) * 2002-12-12 2004-06-24 Osteotech, Inc. Formable and settable polymer bone composite and method of production thereof
US20050251267A1 (en) * 2004-05-04 2005-11-10 John Winterbottom Cell permeable structural implant
US7192447B2 (en) 2002-12-19 2007-03-20 Synthes (Usa) Intervertebral implant
NZ541535A (en) * 2003-02-04 2009-02-28 Osteotech Inc Biodegradable polyurethane composite for osteoimplants
US7985414B2 (en) * 2003-02-04 2011-07-26 Warsaw Orthopedic, Inc. Polyurethanes for osteoimplants
US7648509B2 (en) 2003-03-10 2010-01-19 Ilion Medical Llc Sacroiliac joint immobilization
US20050064042A1 (en) * 2003-04-29 2005-03-24 Musculoskeletal Transplant Foundation Cartilage implant plug with fibrin glue and method for implantation
US7067123B2 (en) * 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
WO2004098457A1 (en) * 2003-04-30 2004-11-18 Therics, Inc. Bone void filler and method of manufacture
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7488348B2 (en) 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
NZ544050A (en) * 2003-06-11 2009-03-31 Osteotech Inc Osteoimplants and methods for their manufacture
US20050020506A1 (en) * 2003-07-25 2005-01-27 Drapeau Susan J. Crosslinked compositions comprising collagen and demineralized bone matrix, methods of making and methods of use
US7806932B2 (en) * 2003-08-01 2010-10-05 Zimmer Spine, Inc. Spinal implant
US20060229627A1 (en) 2004-10-29 2006-10-12 Hunt Margaret M Variable angle spinal surgery instrument
US7163651B2 (en) * 2004-02-19 2007-01-16 Calcitec, Inc. Method for making a porous calcium phosphate article
US6994726B2 (en) * 2004-05-25 2006-02-07 Calcitec, Inc. Dual function prosthetic bone implant and method for preparing the same
US7118705B2 (en) 2003-08-05 2006-10-10 Calcitec, Inc. Method for making a molded calcium phosphate article
US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
WO2005032612A2 (en) * 2003-10-02 2005-04-14 Lostec, Inc. A transplantable particulate bone composition and methods for making and using same
US20050085922A1 (en) * 2003-10-17 2005-04-21 Shappley Ben R. Shaped filler for implantation into a bone void and methods of manufacture and use thereof
WO2005046440A2 (en) * 2003-11-07 2005-05-26 Calcitec, Inc. Spinal fusion procedure using an injectable bone substitute
EP1701672A4 (de) * 2003-12-19 2011-04-27 Osteotech Inc Aus gewebe erhaltenes maschengeflecht für die orthopädische regeneration
US8734525B2 (en) 2003-12-31 2014-05-27 Warsaw Orthopedic, Inc. Osteoinductive demineralized cancellous bone
CA2535169A1 (en) 2003-12-31 2005-07-21 Osteotech, Inc. Improved bone matrix compositions and methods
US8012210B2 (en) 2004-01-16 2011-09-06 Warsaw Orthopedic, Inc. Implant frames for use with settable materials and related methods of use
JP2007519496A (ja) 2004-01-27 2007-07-19 オステオテック,インコーポレイテッド 安定化された骨移植片
US20060015184A1 (en) * 2004-01-30 2006-01-19 John Winterbottom Stacking implants for spinal fusion
US7189263B2 (en) 2004-02-03 2007-03-13 Vita Special Purpose Corporation Biocompatible bone graft material
US20050177245A1 (en) * 2004-02-05 2005-08-11 Leatherbury Neil C. Absorbable orthopedic implants
CA2575740A1 (en) 2004-03-24 2005-10-13 Doctor's Research Group, Inc. Methods of performing medical procedures that promote bone growth, methods of making compositions that promote bone growth, and apparatus for use in such methods
US20070190101A1 (en) * 2004-03-31 2007-08-16 Chunlin Yang Flowable bone grafts
US7942913B2 (en) 2004-04-08 2011-05-17 Ebi, Llc Bone fixation device
US20060228252A1 (en) * 2004-04-20 2006-10-12 Mills C R Process and apparatus for treating implants comprising soft tissue
US7648676B2 (en) * 2004-04-20 2010-01-19 Rti Biologics, Inc. Process and apparatus for treating implants comprising soft tissue
US20050244450A1 (en) * 2004-04-28 2005-11-03 Reddi A H Heat-treated implantable bone material
US7678385B2 (en) * 2004-04-28 2010-03-16 Biomet Manufacturing Corp. Irradiated implantable bone material
US8163030B2 (en) * 2004-05-06 2012-04-24 Degradable Solutions Ag Biocompatible bone implant compositions and methods for repairing a bone defect
WO2005110437A2 (en) * 2004-05-10 2005-11-24 Therics, Inc. Implantable biostructure comprising an osteoconductive member and an osteoinductive material
CA2564605A1 (en) 2004-05-12 2005-12-01 Massachusetts Institute Of Technology Manufacturing process, such as three-dimensional printing, including solvent vapor filming and the like
US7887587B2 (en) 2004-06-04 2011-02-15 Synthes Usa, Llc Soft tissue spacer
KR100750190B1 (ko) 2004-06-16 2007-08-31 요업기술원 골 수복에 효과적인 골 충전재 및 그의 제조 방법
US9220595B2 (en) 2004-06-23 2015-12-29 Orthovita, Inc. Shapeable bone graft substitute and instruments for delivery thereof
US20060039949A1 (en) * 2004-08-20 2006-02-23 Nycz Jeffrey H Acetabular cup with controlled release of an osteoinductive formulation
CA2579041A1 (en) * 2004-09-07 2006-03-16 Smith & Nephew, Inc. Methods and devices for sterile field transfer
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7670384B2 (en) * 2004-10-14 2010-03-02 Biomet Manufacturing Corp. Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US20060083769A1 (en) * 2004-10-14 2006-04-20 Mukesh Kumar Method and apparatus for preparing bone
US20060111779A1 (en) 2004-11-22 2006-05-25 Orthopedic Development Corporation, A Florida Corporation Minimally invasive facet joint fusion
US20060111786A1 (en) * 2004-11-22 2006-05-25 Orthopedic Development Corporation Metallic prosthetic implant for use in minimally invasive acromio-clavicular shoulder joint hemi-arthroplasty
US20060111780A1 (en) 2004-11-22 2006-05-25 Orthopedic Development Corporation Minimally invasive facet joint hemi-arthroplasty
US8021392B2 (en) 2004-11-22 2011-09-20 Minsurg International, Inc. Methods and surgical kits for minimally-invasive facet joint fusion
US8308340B2 (en) 2004-11-23 2012-11-13 Smith & Nephew, Inc. Composite mixer
WO2006060416A2 (en) * 2004-11-30 2006-06-08 Osteobiologics, Inc. Implants and delivery system for treating defects in articulating surfaces
US7527640B2 (en) 2004-12-22 2009-05-05 Ebi, Llc Bone fixation system
MX2007008561A (es) * 2005-01-14 2008-02-21 Osteotech Inc Osteoimplante expandible.
US20060216321A1 (en) * 2005-03-24 2006-09-28 Sdgi Holdings, Inc. Solvent based processing technologies for making tissue/polymer composites
US20060229723A1 (en) * 2005-04-08 2006-10-12 Sdgi Holdings, Inc. Intervertebral fusion device and method
US7621963B2 (en) * 2005-04-13 2009-11-24 Ebi, Llc Composite bone graft material
US20060233849A1 (en) * 2005-04-13 2006-10-19 Simon Bruce J Composite bone graft material
US7879103B2 (en) 2005-04-15 2011-02-01 Musculoskeletal Transplant Foundation Vertebral disc repair
US7857853B2 (en) * 2005-04-29 2010-12-28 Sdgi Holdings, Inc Synthetic loadbearing collagen-mineral composites useful for spinal implants, and methods of manufacture
US20060258578A1 (en) * 2005-05-10 2006-11-16 The University Of Zurich Pharmaceutical composition
US8070749B2 (en) 2005-05-12 2011-12-06 Stern Joseph D Revisable anterior cervical plating system
WO2006124273A2 (en) * 2005-05-12 2006-11-23 Stern Joseph D Revisable anterior cervical plating system
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
US7771590B2 (en) * 2005-08-23 2010-08-10 Biomet Manufacturing Corp. Method and apparatus for collecting biological materials
US8048297B2 (en) * 2005-08-23 2011-11-01 Biomet Biologics, Llc Method and apparatus for collecting biological materials
US20070074980A1 (en) * 2005-09-02 2007-04-05 Bankoski Brian R Implant rehydration packages and methods of use
WO2007035778A2 (en) 2005-09-19 2007-03-29 Histogenics Corporation Cell-support matrix and a method for preparation thereof
US7955364B2 (en) 2005-09-21 2011-06-07 Ebi, Llc Variable angle bone fixation assembly
US7691105B2 (en) * 2005-09-26 2010-04-06 Depuy Spine, Inc. Tissue augmentation, stabilization and regeneration technique
US8911759B2 (en) 2005-11-01 2014-12-16 Warsaw Orthopedic, Inc. Bone matrix compositions and methods
WO2007056671A1 (en) 2005-11-02 2007-05-18 Osteotech, Inc. Hemostatic bone graft
WO2007061889A2 (en) * 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
US7901458B2 (en) * 2005-12-16 2011-03-08 Warsaw Orthopedic, Inc. Intervertebral spacer and insertion tool
US8287914B2 (en) * 2006-01-12 2012-10-16 Rutgers, The State University Of New Jersey Biomimetic hydroxyapatite synthesis
US20100040668A1 (en) * 2006-01-12 2010-02-18 Rutgers, The State University Of New Jersey Biomimetic Hydroxyapatite Composite Materials and Methods for the Preparation Thereof
WO2007084725A2 (en) 2006-01-19 2007-07-26 Osteotech, Inc. Injectable and moldable bone substitute materials
EP1976459A4 (de) 2006-01-19 2012-06-20 Warsaw Orthopedic Inc Poröses knochenimplantat
US7749555B2 (en) * 2006-01-25 2010-07-06 Medtronic, Inc Modification of chemical forces of bone constructs
US7824703B2 (en) * 2006-02-01 2010-11-02 Warsaw Orthopedics, Inc. Medical implants with reservoir(s), and materials preparable from same
EP2311505B1 (de) 2006-02-09 2013-11-06 BioMimetic Therapeutics, LLC Zusammensetzungen und Verfahren zur Behandlung von Knochen
US7732539B2 (en) * 2006-02-16 2010-06-08 National Science Foundation Modified acrylic block copolymers for hydrogels and pressure sensitive wet adhesives
US20070270971A1 (en) * 2006-03-14 2007-11-22 Sdgi Holdings, Inc. Intervertebral prosthetic disc with improved wear resistance
US20070233246A1 (en) * 2006-03-31 2007-10-04 Sdgi Holdings, Inc. Spinal implants with improved mechanical response
US8673019B2 (en) * 2006-04-13 2014-03-18 Warsaw Orthopedic, Inc. Use of anti-inflammatory compounds with allograft tissue implantation
US7771414B2 (en) * 2006-04-24 2010-08-10 Warsaw Orthopedic, Inc. Controlled release devices for therapeutic treatments of spinal discs
US8642060B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for osteal growth
US7879027B2 (en) * 2006-04-24 2011-02-01 Warsaw Orthopedic, Inc. Controlled release devices for fusion of osteal structures
US8642059B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for intervertebral discs
AU2007243353B2 (en) 2006-04-26 2012-05-31 Illuminoss Medical, Inc. Apparatus and methods for reinforcing bone
US7806900B2 (en) 2006-04-26 2010-10-05 Illuminoss Medical, Inc. Apparatus and methods for delivery of reinforcing materials to bone
US20100209470A1 (en) * 2006-05-01 2010-08-19 Warsaw Orthopedic, Inc. An Indiana Corporation Demineralized bone matrix devices
US7838022B2 (en) 2006-05-01 2010-11-23 Warsaw Orthopedic, Inc Malleable implants containing demineralized bone matrix
US7771741B2 (en) 2006-05-01 2010-08-10 Warsaw Orthopedic, Inc Demineralized bone matrix devices
US8506983B2 (en) * 2006-05-01 2013-08-13 Warsaw Orthopedic, Inc. Bone filler material
US20080262633A1 (en) 2006-05-08 2008-10-23 Williams Michelle Leroux Cancellous bone treated with collagenase and essentially free of blood cells
AU2007250080B2 (en) 2006-05-08 2011-08-18 Nuvasive, Inc. Cancellous bone treated with collagenase and essentially free of blood cells
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
WO2008002682A2 (en) * 2006-06-29 2008-01-03 Orthovita, Inc. Bioactive bone graft substitute
AU2007269712B2 (en) 2006-06-30 2013-02-07 Biomimetic Therapeutics, Llc PDGF-biomatrix compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
US20080021462A1 (en) * 2006-07-24 2008-01-24 Warsaw Orthopedic Inc. Spinal stabilization implants
US20080021557A1 (en) * 2006-07-24 2008-01-24 Warsaw Orthopedic, Inc. Spinal motion-preserving implants
EP2076220A2 (de) 2006-07-25 2009-07-08 Musculoskeletal Transplant Foundation Verkapselte entmineralisierte spongiosagewebeformen für bandscheibenkernaugmentation, wiederherstellung oder ersatz sowie implantierverfahren
US20080033572A1 (en) * 2006-08-03 2008-02-07 Ebi L.P. Bone graft composites and methods of treating bone defects
WO2008091386A2 (en) * 2006-08-04 2008-07-31 Northwestern University Biomimetic modular adhesive complex: material, methods and applications therefore
JP5597836B2 (ja) 2006-08-04 2014-10-01 ケンジー ナッシュ コーポレイション バイオミメティック化合物およびその合成方法
US9066994B2 (en) * 2006-08-31 2015-06-30 Warsaw Orthopedic, Inc. Demineralized cancellous strip DBM graft
CA2667000A1 (en) * 2006-09-25 2008-04-03 James P. Murphy Bioactive load-bearing composites comprising peek and bioglass particles
EP2086598B1 (de) 2006-11-03 2015-05-27 BioMimetic Therapeutics, LLC Zusammensetzungen und verfahren für behandlungen von arthrodese
US8388626B2 (en) * 2006-11-08 2013-03-05 Warsaw Orthopedic, Inc. Methods of employing calcium phosphate cement compositions and osteoinductive proteins to effect vertebrae interbody fusion absent an interbody device
WO2008063265A1 (en) 2006-11-10 2008-05-29 Illuminoss Medical, Inc. Systems and methods for internal bone fixation
US7879041B2 (en) 2006-11-10 2011-02-01 Illuminoss Medical, Inc. Systems and methods for internal bone fixation
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US20080195476A1 (en) * 2007-02-09 2008-08-14 Marchese Michael A Abandonment remarketing system
AU2008216371B2 (en) 2007-02-12 2014-04-10 Warsaw Orthopedic, Inc. Joint revision implant
US8673286B2 (en) 2007-04-09 2014-03-18 Northwestern University DOPA-functionalized, branched, poly(aklylene oxide) adhesives
US8383092B2 (en) * 2007-02-16 2013-02-26 Knc Ner Acquisition Sub, Inc. Bioadhesive constructs
US20080206299A1 (en) * 2007-02-27 2008-08-28 Shimp Lawrence A Method for Recovering Minerals From Bone and Use of Same
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
JP2010522046A (ja) 2007-03-22 2010-07-01 ノヴァリン・オルソペディクス・インコーポレーテッド セグメント状髄内構造体
US20080230094A1 (en) * 2007-03-23 2008-09-25 Buckman Laboratories International, Inc. Method to inhibit growth of microorganisms in aqueous systems and on substrates using persulfate and a bromide
US7658940B2 (en) * 2007-03-30 2010-02-09 Skeletal Kinetics, Llc Calcium phosphate cements comprising autologous bone
JP5479319B2 (ja) 2007-04-12 2014-04-23 バイオメット・バイオロジックス・リミテッド・ライアビリティ・カンパニー ブイ式懸濁液分画システム
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
US9554920B2 (en) 2007-06-15 2017-01-31 Warsaw Orthopedic, Inc. Bone matrix compositions having nanoscale textured surfaces
CA2690457C (en) * 2007-06-15 2018-02-20 Osteotech, Inc. Bone matrix compositions and methods
WO2008157497A2 (en) 2007-06-15 2008-12-24 Osteotech, Inc. Method of treating tissue
US20100268339A1 (en) * 2007-07-10 2010-10-21 Malinin Theodore I Intervertebral Spinal Implant and Method of Making the Same
US20090018659A1 (en) * 2007-07-10 2009-01-15 Malinin Theodore I Invertebral spinal implant and method of making the same
US9492278B2 (en) 2007-07-10 2016-11-15 Warsaw Orthopedic, Inc. Delivery system
US9125743B2 (en) * 2007-07-16 2015-09-08 Lifenet Health Devitalization and recellularization of cartilage
US9744043B2 (en) * 2007-07-16 2017-08-29 Lifenet Health Crafting of cartilage
US20090024174A1 (en) 2007-07-17 2009-01-22 Stark John G Bone screws and particular applications to sacroiliac joint fusion
US8512342B2 (en) * 2007-08-11 2013-08-20 Thomas L. Meredith Portable bone grinder
US20090130174A1 (en) * 2007-08-20 2009-05-21 Vanderbilt University Poly (ester urethane) urea foams with enhanced mechanical and biological properties
US9138509B2 (en) * 2007-09-14 2015-09-22 Musculoskeletal Transplant Foundation Composition for filling bone defects
KR100916722B1 (ko) * 2007-10-13 2009-09-14 민병호 홍합본드를 이용한 인공치아 형성방법
JP2011504409A (ja) * 2007-10-16 2011-02-10 エイチケーピービー サイエンティフィック リミテッド 表面コーティング方法およびその使用
WO2009052492A2 (en) 2007-10-19 2009-04-23 Osteotech, Inc. Demineralized bone matrix compositions and methods
WO2009059090A1 (en) 2007-10-31 2009-05-07 Illuminoss Medical, Inc. Light source
WO2009082554A2 (en) 2007-11-09 2009-07-02 Osteotech, Inc. Bone matrix compositions having nanoscale textured surfaces
US9056150B2 (en) 2007-12-04 2015-06-16 Warsaw Orthopedic, Inc. Compositions for treating bone defects
EP2231210A4 (de) * 2007-12-12 2013-01-23 Warsaw Orthopedic Inc Knochen/kollagen-komposite und ihre anwendungen
US8403968B2 (en) 2007-12-26 2013-03-26 Illuminoss Medical, Inc. Apparatus and methods for repairing craniomaxillofacial bones using customized bone plates
JP5864106B2 (ja) 2008-02-07 2016-02-17 バイオミメティック セラピューティクス, エルエルシー 仮骨延長のための組成物および方法
US8740912B2 (en) 2008-02-27 2014-06-03 Ilion Medical Llc Tools for performing less invasive orthopedic joint procedures
EP2620139B1 (de) 2008-02-27 2016-07-20 Biomet Biologics, LLC Interleukin-1-Rezeptorantagonisten-reiche Lösungen
US8337711B2 (en) 2008-02-29 2012-12-25 Biomet Biologics, Llc System and process for separating a material
WO2009111069A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US8840913B2 (en) 2008-03-27 2014-09-23 Warsaw Orthopedic, Inc. Malleable multi-component implants and materials therefor
CN102046237A (zh) 2008-03-28 2011-05-04 骨骼技术股份有限公司 递送系统连接
US20100082072A1 (en) * 2008-03-28 2010-04-01 Sybert Daryl R Bone anchors for orthopedic applications
US20100068171A1 (en) * 2008-05-27 2010-03-18 Vanderbilt University Injectable bone/polymer composite bone void fillers
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
US8883915B2 (en) 2008-07-07 2014-11-11 Biomimedica, Inc. Hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same
WO2010004057A1 (es) * 2008-07-08 2010-01-14 Histocell, S.L MATRICES TRIDIMENSIONALES DE MONETITA POROSA ESTRUCTURADA PARA INGENIERIA TISULAR Y REGENERACION OSEA, Y METODO DE PREPARACIόN DE LAS MISMAS
JP5722773B2 (ja) 2008-08-05 2015-05-27 バイオミメディカ インコーポレイテッド ポリウレタングラフト化ヒドロゲル
JP5816553B2 (ja) 2008-09-09 2015-11-18 バイオミメティック セラピューティクス, エルエルシー 腱または靭帯の傷害を処置するための血小板由来成長因子組成物および方法
WO2010048610A2 (en) 2008-10-24 2010-04-29 Osteotech, Inc. Compositions and methods for promoting bone formation
CA2745038A1 (en) * 2008-10-30 2010-05-27 Osteotech, Inc. Bone/polyurethane composites and methods thereof
WO2012134540A2 (en) 2010-10-22 2012-10-04 Vanderbilt University Injectable synthetic pur composite
US9192695B2 (en) 2008-11-20 2015-11-24 Allosource Allografts combined with tissue derived stem cells for bone healing
PT2389205T (pt) * 2008-12-13 2021-03-29 Bioventus Llc Método de fabrico de implante ósseo osteoindutor
US20100151114A1 (en) * 2008-12-17 2010-06-17 Zimmer, Inc. In-line treatment of yarn prior to creating a fabric
US20100168798A1 (en) 2008-12-30 2010-07-01 Clineff Theodore D Bioactive composites of polymer and glass and method for making same
WO2010093950A1 (en) 2009-02-12 2010-08-19 Osteotech, Inc. Delivery system cartridge
US9821033B2 (en) * 2009-02-27 2017-11-21 Kieran Murphy Llc Modulating bone growth in treating scoliosis
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US9241798B2 (en) * 2009-03-20 2016-01-26 David A. Petersen Surgical methods and tools
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US8210729B2 (en) 2009-04-06 2012-07-03 Illuminoss Medical, Inc. Attachment system for light-conducting fibers
US8512338B2 (en) 2009-04-07 2013-08-20 Illuminoss Medical, Inc. Photodynamic bone stabilization systems and methods for reinforcing bone
US20100297082A1 (en) * 2009-05-19 2010-11-25 Osteotech, Inc. Weight-bearing polyurethane composites and methods thereof
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
USD773047S1 (en) * 2009-07-20 2016-11-29 Teknimed S.A. Bone filler particle
WO2011017284A2 (en) 2009-08-03 2011-02-10 Osteotech, Inc. Bone matrix compositions and methods
US9173748B2 (en) * 2009-08-07 2015-11-03 Ebi, Llc Toroid-shaped spinal disc
US20110035010A1 (en) * 2009-08-07 2011-02-10 Ebi, Llc Toroid-shaped spinal disc
US8926552B2 (en) * 2009-08-12 2015-01-06 Medtronic, Inc. Particle delivery
US8870965B2 (en) 2009-08-19 2014-10-28 Illuminoss Medical, Inc. Devices and methods for bone alignment, stabilization and distraction
WO2011063250A1 (en) * 2009-11-20 2011-05-26 Knee Creations, Llc Implantable devices for subchondral treatment of joint pain
CN102781348B (zh) 2009-11-20 2015-07-15 膝部创造物有限责任公司 用于关节修复的导航和定位仪器
US8801800B2 (en) 2009-11-20 2014-08-12 Zimmer Knee Creations, Inc. Bone-derived implantable devices and tool for subchondral treatment of joint pain
WO2011063257A1 (en) 2009-11-20 2011-05-26 Knee Creations, Llc Instruments for targeting a joint defect
US8906032B2 (en) 2009-11-20 2014-12-09 Zimmer Knee Creations, Inc. Instruments for a variable angle approach to a joint
CN102770067A (zh) 2009-11-20 2012-11-07 膝部创造物有限责任公司 用于关节治疗的坐标映射系统
US8821504B2 (en) 2009-11-20 2014-09-02 Zimmer Knee Creations, Inc. Method for treating joint pain and associated instruments
US8608802B2 (en) 2009-11-20 2013-12-17 Zimmer Knee Creations, Inc. Implantable devices for subchondral treatment of joint pain
US8951261B2 (en) 2009-11-20 2015-02-10 Zimmer Knee Creations, Inc. Subchondral treatment of joint pain
US20110130465A1 (en) * 2009-12-01 2011-06-02 Nerites Corporation Coatings for prevention of biofilms
CN102781487B (zh) 2009-12-13 2016-11-16 阿米特·普拉卡什·戈维 生物活性移植物和复合物
US8778378B2 (en) * 2009-12-21 2014-07-15 Orthovita, Inc. Bioactive antibacterial bone graft materials
US9125902B2 (en) 2010-01-28 2015-09-08 Warsaw Orthopedic, Inc. Methods for treating an intervertebral disc using local analgesics
US9486500B2 (en) 2010-01-28 2016-11-08 Warsaw Orthopedic, Inc. Osteoimplant and methods for making
US9050274B2 (en) * 2010-01-28 2015-06-09 Warsaw Orthopedic, Inc. Compositions and methods for treating an intervertebral disc using bulking agents or sealing agents
US20110189253A1 (en) * 2010-01-29 2011-08-04 Warsaw Orthopedic, Inc. Biomaterial composition and method
MX2012009687A (es) 2010-02-22 2012-11-29 Biomimetic Therapeutics Inc Metodos y composiciones de factor de crecimiento derivado de plaquetas y métodos para el tratamiento de tendinopatías.
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8684965B2 (en) 2010-06-21 2014-04-01 Illuminoss Medical, Inc. Photodynamic bone stabilization and drug delivery systems
EP2608778B1 (de) * 2010-08-26 2017-11-01 University of Louisville Research Foundation, Inc. Zusammensetzungen und verfahren zur behandlung von knochendefekten
EP2637707A4 (de) 2010-11-09 2014-10-01 Kensey Nash Corp Haftverbindungen und anwendungsverfahren für herniereparatur
AU2011329054B2 (en) 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
WO2012088432A1 (en) 2010-12-22 2012-06-28 Illuminoss Medical, Inc. Systems and methods for treating conditions and diseases of the spine
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
EP3733099B1 (de) * 2011-02-28 2022-08-31 DePuy Synthes Products, Inc. Modulare gewebegerüste
US8673014B2 (en) 2011-04-01 2014-03-18 Kls-Martin, L.P. Method of cranial repair and cranial repair implant molding device
US20140236312A1 (en) * 2011-05-10 2014-08-21 Mark R. Appleford Cortical bone scaffold for guided osteon regeneration in load-bearing orthopaedic applications
US8936644B2 (en) 2011-07-19 2015-01-20 Illuminoss Medical, Inc. Systems and methods for joint stabilization
US9775661B2 (en) 2011-07-19 2017-10-03 Illuminoss Medical, Inc. Devices and methods for bone restructure and stabilization
DE102011112249A1 (de) * 2011-09-01 2013-03-07 Heinrich-Heine-Universität Düsseldorf Dentale Füllmaterialmischung zur Füllung von Wurzelkanälen
US10881526B2 (en) 2011-09-16 2021-01-05 Globus Medical, Inc. Low profile plate
US9237957B2 (en) 2011-09-16 2016-01-19 Globus Medical, Inc. Low profile plate
US10245155B2 (en) 2011-09-16 2019-04-02 Globus Medical, Inc. Low profile plate
US9204975B2 (en) 2011-09-16 2015-12-08 Globus Medical, Inc. Multi-piece intervertebral implants
US8961606B2 (en) 2011-09-16 2015-02-24 Globus Medical, Inc. Multi-piece intervertebral implants
US9848994B2 (en) 2011-09-16 2017-12-26 Globus Medical, Inc. Low profile plate
US9149365B2 (en) 2013-03-05 2015-10-06 Globus Medical, Inc. Low profile plate
US9398960B2 (en) 2011-09-16 2016-07-26 Globus Medical, Inc. Multi-piece intervertebral implants
US9770340B2 (en) 2011-09-16 2017-09-26 Globus Medical, Inc. Multi-piece intervertebral implants
US9681959B2 (en) 2011-09-16 2017-06-20 Globus Medical, Inc. Low profile plate
US9539109B2 (en) 2011-09-16 2017-01-10 Globus Medical, Inc. Low profile plate
EP3357518B1 (de) 2011-10-03 2020-12-02 Hyalex Orthopaedics, Inc. Polymerer klebstoff zur verankerung von nachgiebigen materialien auf einer anderen oberfläche
US20140370094A1 (en) 2011-11-08 2014-12-18 Tufts University Silk-based scaffold platform for engineering tissue constructs
US8920511B2 (en) 2011-11-17 2014-12-30 Allosource Multi-piece machine graft systems and methods
WO2013078284A1 (en) 2011-11-21 2013-05-30 Biomimedica, Inc. Systems, devices, and methods for anchoring orthopaedic implants to bone
US9554914B2 (en) 2011-12-12 2017-01-31 Wright Medical Technology, Inc. Fusion implant
US8992628B2 (en) 2012-01-20 2015-03-31 Warsaw Orthopedic, Inc. Bone delivery system
US9198758B2 (en) 2012-01-26 2015-12-01 Warsaw Orthopedic, Inc. Delivery systems
US9775862B2 (en) 2012-01-30 2017-10-03 Warsaw Orthopedic, Inc. Modification of reactivity of bone constructs
US8926622B2 (en) 2012-04-03 2015-01-06 Warsaw Orthopedic, Inc. Bone delivery systems including holding and filling devices and methods
KR20150035588A (ko) 2012-05-11 2015-04-06 알티아이 서지칼, 인크. 이종이식 연조직 이식물 및 제조 및 사용 방법
US8939977B2 (en) 2012-07-10 2015-01-27 Illuminoss Medical, Inc. Systems and methods for separating bone fixation devices from introducer
US9655994B2 (en) 2012-07-25 2017-05-23 William F. McKay Delivery systems
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US10172651B2 (en) * 2012-10-25 2019-01-08 Warsaw Orthopedic, Inc. Cortical bone implant
US10780197B1 (en) 2012-10-29 2020-09-22 Nuvasive, Inc. Malleable, cryopreserved osteogenic compositions with viable cells
US9687281B2 (en) 2012-12-20 2017-06-27 Illuminoss Medical, Inc. Distal tip for bone fixation devices
US9265609B2 (en) 2013-01-08 2016-02-23 Warsaw Orthopedic, Inc. Osteograft implant
US9034052B2 (en) 2013-01-14 2015-05-19 Warsaw Orthopedic, Inc. Delivery systems containing bioactive materials
KR102215401B1 (ko) 2013-02-22 2021-02-10 알로소스 연골 모자이크 조성물 및 방법
US9283013B2 (en) 2013-03-14 2016-03-15 Warsaw Orthopedic, Inc. Filling systems for bone delivery devices
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US9119732B2 (en) 2013-03-15 2015-09-01 Orthocision, Inc. Method and implant system for sacroiliac joint fixation and fusion
US9168140B2 (en) 2013-03-15 2015-10-27 Allosource Perforated osteochondral allograft compositions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
CA2899713C (en) 2013-03-15 2022-07-19 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
WO2015054547A1 (en) * 2013-10-09 2015-04-16 Lifenet Health Compressed bone composition and methods of use thereof
RU2557893C1 (ru) * 2014-04-10 2015-07-27 Федеральное государственное бюджетное учреждение "Центральный научно-исследовательский институт травматологии и ортопедии имени Н.Н. Приорова" Министерства здравоохранения Российской Федерации (ФГБУ "ЦИТО им. Н.Н. Приорова" Минздрава России) Способ двухэтапного хирургического лечения деформации позвоночника с использованием аутоконсервации резецированного ауторебра и сухой вертикальной гало-тракции
US9364583B2 (en) 2014-04-25 2016-06-14 Warsaw Orthopedic, Inc. Osteoinductive demineralized bone implant
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CN104606713B (zh) * 2015-01-04 2017-04-19 浙江大学 三维平行胶原纤维-蚕丝支架及其制备方法与应用
US10238507B2 (en) 2015-01-12 2019-03-26 Surgentec, Llc Bone graft delivery system and method for using same
US10610366B2 (en) 2015-01-29 2020-04-07 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
US10006705B2 (en) 2015-02-09 2018-06-26 Warsaw Orthopedic, Inc. Methods for treating tissue materials
RU2597786C2 (ru) * 2015-02-10 2016-09-20 Общество с ограниченной ответственностью "НекстГен" Способ создания персонализированного ген-активированного имплантата для регенерации костной ткани
US10779960B2 (en) * 2015-02-27 2020-09-22 In2Bones Usa, Llc Engineered sterile cartilage allograft implant plug with sterile, specific instrument kit(s)
US10531957B2 (en) 2015-05-21 2020-01-14 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
US10383731B2 (en) 2016-02-24 2019-08-20 Warsaw Orthopedic, Inc. Spinal implant system and method
ES2579305B1 (es) * 2016-04-29 2017-03-24 Optimus 3D S.L. Procedimiento de obtención de un implante activo de uso en la regeneración de masa ósea y correspondiente implante obtenido
WO2017201259A1 (en) 2016-05-18 2017-11-23 Rti Surgical, Inc. Osteoinductive nanofiber scaffold for bone regeneration
WO2018071053A1 (en) * 2016-10-14 2018-04-19 Allosource Consistent calcium content bone allograft systems and methods
US11141276B2 (en) 2017-01-20 2021-10-12 Biomet Manufacturing, Llc Modular augment component
US11452608B2 (en) 2017-04-05 2022-09-27 Globus Medical, Inc. Decoupled spacer and plate and method of installing the same
US10376385B2 (en) 2017-04-05 2019-08-13 Globus Medical, Inc. Decoupled spacer and plate and method of installing the same
US10064726B1 (en) 2017-04-18 2018-09-04 Warsaw Orthopedic, Inc. 3D printing of mesh implants for bone delivery
US11660196B2 (en) 2017-04-21 2023-05-30 Warsaw Orthopedic, Inc. 3-D printing of bone grafts
US11452796B2 (en) 2017-06-30 2022-09-27 Allosource Cellular bone grafts, and methods of manufacture and use
EP3656785A4 (de) * 2017-07-18 2020-07-15 Posco Antimikrobielles adhäsionsprotein, antimikrobieller nanopartikel, antimikrobielle zusammensetzung mit dem nanopartikel und verfahren zur herstellung der zusammensetzung
US10970789B2 (en) 2018-01-23 2021-04-06 Full Circle Innovation Llc Systems and methods for facilitating insurance coverage
US11147567B2 (en) 2018-02-28 2021-10-19 Joint Restoration Foundation, Inc. Methods and devices for restoration of a bone surface
US10687828B2 (en) 2018-04-13 2020-06-23 Surgentec, Llc Bone graft delivery system and method for using same
US11116647B2 (en) 2018-04-13 2021-09-14 Surgentec, Llc Bone graft delivery system and method for using same
WO2020006239A1 (en) 2018-06-27 2020-01-02 Illuminoss Medical, Inc. Systems and methods for bone stabilization and fixation
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
CN111973797B (zh) * 2020-09-04 2022-06-03 湖南奥星生物医药股份有限公司 一种骨科用无创植入高黏度胶材料及其制备方法及应用
USD993452S1 (en) * 2021-09-13 2023-07-25 Regenbiotech, Inc. Medical filler for scaffold for optimizing tissue regeneration

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030583B1 (de) 1979-12-18 1984-06-13 Oscobal Ag Knochenersatzmaterial und Verfahren zur Herstellung eines Knochenersatzmaterials
US4637931A (en) 1984-10-09 1987-01-20 The United States Of America As Represented By The Secretary Of The Army Polyactic-polyglycolic acid copolymer combined with decalcified freeze-dried bone for use as a bone repair material
US4743259A (en) 1986-10-29 1988-05-10 The University Of Virginia Alumni Patents Foundation Use of demineralized bone matrix in the repair of segmental defects
US4902296A (en) 1986-10-29 1990-02-20 The University Of Virginia Alumni Patents Foundation Use of demineralized bone matrix in the repair of segmental defects
CA1339083C (en) 1987-11-13 1997-07-29 Steven R. Jefferies Bone repair material and delayed drug delivery system
US5219576A (en) * 1988-06-30 1993-06-15 Collagen Corporation Collagen wound healing matrices and process for their production
US5207710A (en) 1988-09-29 1993-05-04 Collagen Corporation Method for improving implant fixation
US5061286A (en) * 1989-08-18 1991-10-29 Osteotech, Inc. Osteoprosthetic implant
US5290558A (en) 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
JPH03131263A (ja) * 1989-10-16 1991-06-04 Nippon Electric Glass Co Ltd 生体用セメント
US5314476A (en) * 1992-02-04 1994-05-24 Osteotech, Inc. Demineralized bone particles and flowable osteogenic composition containing same
JPH0753204A (ja) * 1993-08-18 1995-02-28 S T K Ceramics Kenkyusho:Kk リン酸カルシウム系自己硬化型組成物
US5507813A (en) * 1993-12-09 1996-04-16 Osteotech, Inc. Shaped materials derived from elongate bone particles
US5709683A (en) 1995-12-19 1998-01-20 Spine-Tech, Inc. Interbody bone implant having conjoining stabilization features for bony fusion
US5814084A (en) 1996-01-16 1998-09-29 University Of Florida Tissue Bank, Inc. Diaphysial cortical dowel
CA2243365C (en) 1996-01-17 2006-07-25 Michael Dowd Process and apparatus for producing flexible sheets from demineralized, elongate, bone particles
US5824078A (en) * 1996-03-11 1998-10-20 The Board Of Trustees Of The University Of Arkansas Composite allograft, press, and methods
US5868749A (en) 1996-04-05 1999-02-09 Reed; Thomas M. Fixation devices
JP4014698B2 (ja) * 1997-07-15 2007-11-28 ペンタックス株式会社 リン酸カルシウム系セラミックス多孔体の作製方法
US5899939A (en) * 1998-01-21 1999-05-04 Osteotech, Inc. Bone-derived implant for load-supporting applications
US6123731A (en) 1998-02-06 2000-09-26 Osteotech, Inc. Osteoimplant and method for its manufacture
US6294187B1 (en) * 1999-02-23 2001-09-25 Osteotech, Inc. Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same

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