DE60127379D1 - Funktionelle beschichtung von linezolidmikrokapseln zur geschmacksmaskierung und damit verbundene oral anzuwendende arzneizubereitung - Google Patents
Funktionelle beschichtung von linezolidmikrokapseln zur geschmacksmaskierung und damit verbundene oral anzuwendende arzneizubereitungInfo
- Publication number
- DE60127379D1 DE60127379D1 DE60127379T DE60127379T DE60127379D1 DE 60127379 D1 DE60127379 D1 DE 60127379D1 DE 60127379 T DE60127379 T DE 60127379T DE 60127379 T DE60127379 T DE 60127379T DE 60127379 D1 DE60127379 D1 DE 60127379D1
- Authority
- DE
- Germany
- Prior art keywords
- linezolid
- taste
- masked
- fast
- disintegrating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17723300P | 2000-01-20 | 2000-01-20 | |
US09/506,051 US6451345B1 (en) | 2000-01-20 | 2000-02-17 | Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration |
PCT/US2001/001414 WO2001052848A2 (en) | 2000-01-20 | 2001-01-16 | Functional coating of linezolid microcapsules for oral administration |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60127379D1 true DE60127379D1 (de) | 2007-05-03 |
Family
ID=26873062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60127379T Expired - Lifetime DE60127379D1 (de) | 2000-01-20 | 2001-01-16 | Funktionelle beschichtung von linezolidmikrokapseln zur geschmacksmaskierung und damit verbundene oral anzuwendende arzneizubereitung |
Country Status (6)
Country | Link |
---|---|
US (1) | US6451345B1 (de) |
EP (1) | EP1248616B1 (de) |
AT (1) | ATE357231T1 (de) |
AU (1) | AU2001227915A1 (de) |
DE (1) | DE60127379D1 (de) |
WO (1) | WO2001052848A2 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2795962B1 (fr) * | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
US20030091634A1 (en) * | 2001-09-14 | 2003-05-15 | Pawan Seth | Delayed release tablet of venlafaxin |
US7488496B2 (en) | 2002-03-06 | 2009-02-10 | Christer Rosen | Effervescent compositions comprising bisphosphonates and methods related thereto |
AU2002368090A1 (en) * | 2002-07-17 | 2004-02-09 | Eurand Pharmaceuticals Ltd | Process for the preparation of pharmaceutical microcapsules with enhanced tastemasking and high dissolution rate |
CA2492874C (en) * | 2002-07-19 | 2011-09-20 | Aventis Pharma S.A. | Taste masked oral composition of telithromycin |
US20040013737A1 (en) * | 2002-07-19 | 2004-01-22 | Philippe Becourt | Taste masked oral composition of telithromycin |
US20040208936A1 (en) * | 2002-07-22 | 2004-10-21 | Roland Chorin | Novel compositions |
US6875784B2 (en) * | 2002-10-09 | 2005-04-05 | Pharmacia & Upjohn Company | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives |
US20040191326A1 (en) * | 2003-03-31 | 2004-09-30 | Reo Joseph P. | Taste-masking vehicle for coated oxazolidinone particles |
US20040265372A1 (en) * | 2003-06-27 | 2004-12-30 | David Wynn | Soft tablet containing high molecular weight cellulosics |
US20040265373A1 (en) * | 2003-06-27 | 2004-12-30 | David Wynn | Soft tablet containing high molecular weight cellulosics |
US7632521B2 (en) * | 2003-07-15 | 2009-12-15 | Eurand, Inc. | Controlled release potassium chloride tablets |
US8168228B2 (en) * | 2003-10-17 | 2012-05-01 | Sandoz Ag | Antibiotic clarithromycin micropellet compositions |
US7387793B2 (en) | 2003-11-14 | 2008-06-17 | Eurand, Inc. | Modified release dosage forms of skeletal muscle relaxants |
US8545881B2 (en) | 2004-04-19 | 2013-10-01 | Eurand Pharmaceuticals, Ltd. | Orally disintegrating tablets and methods of manufacture |
IS7724A (is) * | 2005-03-02 | 2006-09-03 | Actavis Group | Samsetning á töflum með hraða sundrun sem innihalda þungt magnesíum karbónat |
US20070098746A1 (en) * | 2005-11-02 | 2007-05-03 | Nichols William M | Multi-layered coating technology for taste masking |
US20080014257A1 (en) * | 2006-07-14 | 2008-01-17 | Par Pharmaceutical, Inc. | Oral dosage forms |
JP5228359B2 (ja) * | 2007-04-12 | 2013-07-03 | ニプロ株式会社 | 主薬粒子及びその製造方法ならびに口腔内崩壊錠 |
FR2918296B1 (fr) | 2007-07-05 | 2009-09-18 | Oreal | Capsules de type noyau/ecorce et procede de preparation |
TW200938186A (en) * | 2008-02-13 | 2009-09-16 | Eurand Inc | Orally disintegrating tablet compositions of ranitidine and methods of manufacture |
WO2010046933A2 (en) | 2008-10-22 | 2010-04-29 | Rubicon Research Private Limited | Pharmaceutical compositions of taste-masked linezolid |
CA2750059C (en) | 2009-01-30 | 2014-11-18 | Sunovion Pharmaceuticals Inc. | Coated tablets of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine and methods for measuring effectiveness of coating |
WO2011080570A2 (en) | 2009-12-29 | 2011-07-07 | Micro Labs Limited | Extended release pharmaceutical composition comprising linezolid and process for preparing the same |
CA2802994A1 (en) | 2010-06-17 | 2011-12-22 | The United States Of America As Represented By The Secretary, National I Nstitutes Of Health | Compositions and methods for treating inflammatory conditions |
KR101944124B1 (ko) * | 2010-11-24 | 2019-01-30 | 멜린타 서브시디어리 코프. | 약학 조성물 |
CA2778748A1 (en) * | 2011-06-01 | 2012-12-01 | Nitto Denko Corporation | Particulate preparation and method for producing the same |
EP2719377B1 (de) * | 2011-06-10 | 2018-04-18 | Nipro Corporation | Verfahren zur herstellung von im mund zersetzbaren tabletten |
WO2013088389A1 (en) * | 2011-12-14 | 2013-06-20 | Alembic Pharmaceuticals Limited | Linezolid premix |
GR1008143B (el) | 2013-03-11 | 2014-03-14 | "Φαρματεν Α.Β.Ε.Ε.", | Φαρμακευτικο σκευασμα περιεχον ενα οξαζολιδινονικο αντιβακτηριακο παραγοντα και μεθοδος για την παρασκευη αυτου |
CN104739788B (zh) * | 2013-12-27 | 2018-02-16 | 桂林南药股份有限公司 | 一种小儿利奈唑胺组合物冻干口腔崩解片及其制备方法 |
EP3110403B1 (de) * | 2014-02-25 | 2019-11-06 | Orbis Biosciences, Inc. | Geschmacksmaskierende arzneimittelformulierungen |
CN105055354B (zh) * | 2015-09-08 | 2017-11-21 | 深圳万乐药业有限公司 | 一种利奈唑胺片及其制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4800087A (en) | 1986-11-24 | 1989-01-24 | Mehta Atul M | Taste-masked pharmaceutical compositions |
US4948801A (en) | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
US5084278A (en) * | 1989-06-02 | 1992-01-28 | Nortec Development Associates, Inc. | Taste-masked pharmaceutical compositions |
US5082669A (en) | 1989-07-20 | 1992-01-21 | Dainippon Pharmaceutical Co., Ltd. | Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked |
IT1246382B (it) | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
US5075114A (en) | 1990-05-23 | 1991-12-24 | Mcneil-Ppc, Inc. | Taste masking and sustained release coatings for pharmaceuticals |
CA2122286A1 (en) * | 1993-04-28 | 1994-10-29 | Hiroshi Matoba | Solid preparation and its production |
US5840332A (en) * | 1996-01-18 | 1998-11-24 | Perio Products Ltd. | Gastrointestinal drug delivery system |
ES2193592T3 (es) | 1997-11-18 | 2003-11-01 | Upjohn Co | Uso de derivados de la oxazolidinona para el tratamiento de la artritis. |
CA2318969A1 (en) | 1998-01-23 | 1999-07-29 | Mikhail F. Gordeev | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
-
2000
- 2000-02-17 US US09/506,051 patent/US6451345B1/en not_active Expired - Lifetime
-
2001
- 2001-01-16 EP EP01902073A patent/EP1248616B1/de not_active Expired - Lifetime
- 2001-01-16 AT AT01902073T patent/ATE357231T1/de not_active IP Right Cessation
- 2001-01-16 AU AU2001227915A patent/AU2001227915A1/en not_active Abandoned
- 2001-01-16 WO PCT/US2001/001414 patent/WO2001052848A2/en active IP Right Grant
- 2001-01-16 DE DE60127379T patent/DE60127379D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2001052848A3 (en) | 2001-12-13 |
EP1248616B1 (de) | 2007-03-21 |
US6451345B1 (en) | 2002-09-17 |
EP1248616A2 (de) | 2002-10-16 |
ATE357231T1 (de) | 2007-04-15 |
AU2001227915A1 (en) | 2001-07-31 |
WO2001052848A2 (en) | 2001-07-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60127379D1 (de) | Funktionelle beschichtung von linezolidmikrokapseln zur geschmacksmaskierung und damit verbundene oral anzuwendende arzneizubereitung | |
Nagar et al. | Orally disintegrating tablets: formulation, preparation techniques and evaluation | |
EP1248594B1 (de) | Formulierung mit mehrfach gepulster wirkstofffreisetzung | |
HUP0201877A2 (hu) | Hal zselatint tartalmazó, gyorsan diszpergálódó dózis formák | |
ES2201465T3 (es) | Formulado de comprimidos de monohidrato de cefadroxil. | |
IL163653A (en) | Wafer-shaped pharmaceutical preparation for administering active substances having an unpleasant or bitter taste via the oral mucosa and use of at least one carbon dioxide-forming substance for masking the unpleasant taste of said preparation | |
DE69527842D1 (de) | Oral anzuwendendes flüssiges arzneimittel enthaltend alendronat | |
CA2326517A1 (en) | New galenic preparations of meloxicam for oral administration | |
CA2307018A1 (en) | Osmotic medicament releasing system | |
ATE215816T1 (de) | Feste oral anzuwendende arzeneiform | |
WO2002067903A3 (en) | Compositions and methods of manufacture for oral dissolvable dosage forms | |
AU2002216701A1 (en) | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs | |
EP1161956A4 (de) | Medikamentenzusammensetzung | |
HUP0000943A2 (hu) | Expandálható gasztro-retentív terápiás rendszer szabályozott hatóanyag felszabadítással a gyomor-béltraktusban | |
DE69519685D1 (de) | Oral anzuwendende arzneizubereitung mit verzögerter wirkstoffabgabe | |
US5702723A (en) | Multi-stage delivery system for ingestible medications or nutrients | |
CA2653030A1 (en) | Ache-nmda combination wafer | |
HUP0105481A2 (hu) | Klaritromicint vagy származékait tartalmazó gyógyászati készítmények és eljárás előállításukra, valamint alkalmazásuk | |
CA2652476A1 (en) | Combination antidepressants wafer | |
EA012324B1 (ru) | Быстрораспадающаяся таблетка | |
HUP0203148A2 (hu) | Mirtazapint tartalmazó orálisan dezintegrálódó készítmény | |
EP0271151A3 (de) | Azumolen-Dosisformen | |
WO2002056867A3 (en) | Extended release pharmaceutical compositions containing beta-lactam antibiotics | |
US9339475B2 (en) | Spatial arrangement of particles in a drinking device for oral delivery of pharmaceuticals | |
US20180318228A1 (en) | Method for a slow release of drugs from orally dissolving capsules |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |