DE60143347D1 - Verfahren und vorrichtung zur bestimmung mehrerer analyten - Google Patents

Verfahren und vorrichtung zur bestimmung mehrerer analyten

Info

Publication number
DE60143347D1
DE60143347D1 DE60143347T DE60143347T DE60143347D1 DE 60143347 D1 DE60143347 D1 DE 60143347D1 DE 60143347 T DE60143347 T DE 60143347T DE 60143347 T DE60143347 T DE 60143347T DE 60143347 D1 DE60143347 D1 DE 60143347D1
Authority
DE
Germany
Prior art keywords
pattern
substrate
analytes
assay
diffraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60143347T
Other languages
English (en)
Inventor
Cynthia M Goh
Jane B Goh
Richard Mcaloney
Richard Loo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axela Inc
Original Assignee
Axela Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axela Inc filed Critical Axela Inc
Application granted granted Critical
Publication of DE60143347D1 publication Critical patent/DE60143347D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4788—Diffraction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
    • C12Q2565/513—Detection characterised by immobilisation to a surface characterised by the pattern of the arrayed oligonucleotides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0429—Sample carriers adapted for special purposes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags
DE60143347T 2000-03-22 2001-03-22 Verfahren und vorrichtung zur bestimmung mehrerer analyten Expired - Lifetime DE60143347D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19134400P 2000-03-22 2000-03-22
PCT/CA2001/000367 WO2001071322A2 (en) 2000-03-22 2001-03-22 Method and apparatus for multiple-analyte assay

Publications (1)

Publication Number Publication Date
DE60143347D1 true DE60143347D1 (de) 2010-12-09

Family

ID=22705100

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60143347T Expired - Lifetime DE60143347D1 (de) 2000-03-22 2001-03-22 Verfahren und vorrichtung zur bestimmung mehrerer analyten

Country Status (8)

Country Link
US (2) US7008794B2 (de)
EP (1) EP1266207B1 (de)
JP (1) JP4999249B2 (de)
AT (1) ATE486275T1 (de)
AU (1) AU2001242173A1 (de)
CA (1) CA2403427C (de)
DE (1) DE60143347D1 (de)
WO (1) WO2001071322A2 (de)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003533692A (ja) * 2000-05-06 2003-11-11 ツェプトゼンス アクチエンゲゼルシャフト 多重分析対象物測定及びその使用のための格子導波路構造
ATE462137T1 (de) * 2001-01-16 2010-04-15 Univ Catholique Louvain Chemische oberflächenveränderung optischer elemente
US20040166593A1 (en) * 2001-06-22 2004-08-26 Nolte David D. Adaptive interferometric multi-analyte high-speed biosensor
JP4554205B2 (ja) * 2001-09-13 2010-09-29 アクセラ インコーポレーテッド 光の回折に基づく検定のための方法および装置
GR1004178B (el) * 2001-11-29 2003-03-05 "����������" Ολοκληρωμενος οπτοηλεκτρονικος βιοαισθητηρας πυριτιου για ανιχνευση βιομοριων επισημασμενων με χρωμοφορες ομαδες ή νανοσωματιδια
US7361310B1 (en) * 2001-11-30 2008-04-22 Northwestern University Direct write nanolithographic deposition of nucleic acids from nanoscopic tips
US7102752B2 (en) * 2001-12-11 2006-09-05 Kimberly-Clark Worldwide, Inc. Systems to view and analyze the results from diffraction-based diagnostics
US7098041B2 (en) * 2001-12-11 2006-08-29 Kimberly-Clark Worldwide, Inc. Methods to view and analyze the results from diffraction-based diagnostics
US7399445B2 (en) 2002-01-11 2008-07-15 Canon Kabushiki Kaisha Chemical sensor
GB2388189B (en) * 2002-04-29 2006-01-11 Robert Jeffrey Geddes Carr Optical detection and analysis of particles
US7214530B2 (en) 2002-05-03 2007-05-08 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic devices and method for producing biomolecule diagnostic devices
US7771922B2 (en) 2002-05-03 2010-08-10 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic device
US7485453B2 (en) * 2002-05-03 2009-02-03 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
WO2004031072A2 (en) * 2002-05-21 2004-04-15 Northwestern University Electrostatically driven lithography
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7901630B2 (en) * 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7164533B2 (en) * 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7508608B2 (en) * 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US7900836B2 (en) * 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7872804B2 (en) * 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7441703B2 (en) * 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US20050227252A1 (en) * 2002-08-20 2005-10-13 Moon John A Diffraction grating-based encoded articles for multiplexed experiments
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
US7092160B2 (en) * 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
JP4380977B2 (ja) * 2002-10-28 2009-12-09 東洋紡績株式会社 表面プラズモン共鳴測定用フローセル
US7445938B2 (en) * 2003-01-24 2008-11-04 General Dynamics Advanced Information Systems, Inc. System and method for detecting presence of analytes using gratings
AU2003900924A0 (en) * 2003-02-28 2003-03-13 Medsaic Pty Ltd Imaging device
EP1616169B1 (de) * 2003-03-27 2009-06-24 Corning Incorporated Markierungsfreier nachweis biologischer und chemischer stoffe mittels evaneszenzfeld
US7651850B2 (en) * 2003-05-16 2010-01-26 Board Of Regents, The University Of Texas System Image and part recognition technology
WO2005003743A2 (en) * 2003-05-20 2005-01-13 University Of Maryland Apparatus and methods for surface plasmon-coupled directional emission
US20060057729A1 (en) * 2003-09-12 2006-03-16 Illumina, Inc. Diffraction grating-based encoded element having a substance disposed thereon
EP1673614A1 (de) * 2003-10-01 2006-06-28 CiDra Corporation Optisches lesegerät für codierte optische identifikationselemente auf beugungsgitterbasis
WO2005050207A2 (en) * 2003-11-14 2005-06-02 Illumina Incorporated Diffraction grating-based encoded articles for multiplexed experiments
US20050148063A1 (en) * 2003-12-24 2005-07-07 Cracauer Raymond F. Disposable reaction vessel with integrated optical elements
US20050164373A1 (en) * 2004-01-22 2005-07-28 Oldham Mark F. Diffusion-aided loading system for microfluidic devices
US7433123B2 (en) * 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
DE102004034486B4 (de) * 2004-07-16 2007-08-23 Infineon Technologies Ag Verfahren zum Nachweis von Lumineszenzlicht aus einer porösen Trägerstruktur
GB0416132D0 (en) * 2004-07-19 2004-08-18 Univ Cambridge Tech Production of a sensor
WO2006020363A2 (en) * 2004-07-21 2006-02-23 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
US7939022B2 (en) * 2004-08-05 2011-05-10 Avago Technologies General Ip (Singapore) Pte. Ltd. Integration of colorimetric transducers and detector
US20060242740A1 (en) * 2004-08-11 2006-10-26 California Institute Of Technology Method and device for surfactant activated Dip-Pen Nanolithography
WO2006055736A1 (en) 2004-11-16 2006-05-26 Illumina, Inc. And methods and apparatus for reading coded microbeads
US7604173B2 (en) * 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
US20070023643A1 (en) * 2005-02-01 2007-02-01 Nolte David D Differentially encoded biological analyzer planar array apparatus and methods
US7663092B2 (en) * 2005-02-01 2010-02-16 Purdue Research Foundation Method and apparatus for phase contrast quadrature interferometric detection of an immunoassay
US7910356B2 (en) * 2005-02-01 2011-03-22 Purdue Research Foundation Multiplexed biological analyzer planar array apparatus and methods
EP1938049B1 (de) * 2005-09-22 2019-01-02 Koninklijke Philips N.V. Lumineszenzsensor mit mindestens zwei drahtgittern
US7623624B2 (en) * 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
WO2007131103A2 (en) * 2006-05-03 2007-11-15 Quadraspec, Inc. Direct printing of patterned hydrophobic wells
AU2007247740A1 (en) * 2006-05-09 2007-11-15 Axela Inc. Automated analyzer using light diffraction
JP5178049B2 (ja) * 2006-05-12 2013-04-10 キヤノン株式会社 標的物質検出素子、標的物質検出装置、及び標的物質検出方法
JP5855332B2 (ja) * 2006-10-18 2016-02-09 アクセラ インコーポレーテッド 広い濃度範囲にわたる複数アナライトの光回折による測定
US7522282B2 (en) * 2006-11-30 2009-04-21 Purdue Research Foundation Molecular interferometric imaging process and apparatus
US20080144899A1 (en) * 2006-11-30 2008-06-19 Manoj Varma Process for extracting periodic features from images by template matching
US20080230605A1 (en) * 2006-11-30 2008-09-25 Brian Weichel Process and apparatus for maintaining data integrity
US7659968B2 (en) 2007-01-19 2010-02-09 Purdue Research Foundation System with extended range of molecular sensing through integrated multi-modal data acquisition
GB0701201D0 (en) * 2007-01-22 2007-02-28 Cancer Rec Tech Ltd Cell mapping and tracking
JP2008192855A (ja) * 2007-02-05 2008-08-21 Canon Inc 測定装置、露光装置及びデバイス製造方法
WO2008118934A1 (en) * 2007-03-26 2008-10-02 Purdue Research Foundation Method and apparatus for conjugate quadrature interferometric detection of an immunoassay
WO2008128352A1 (en) * 2007-04-19 2008-10-30 Axela, Inc. Methods and compositions for signal amplification
JP5203453B2 (ja) * 2007-05-18 2013-06-05 アクセラ インク． 集積光学および流体制御要素を有する反応容器
WO2009013707A2 (en) * 2007-07-26 2009-01-29 Koninklijke Philips Electronics N.V. A carrier for optical examinations with light reflections
WO2009065087A1 (en) 2007-11-14 2009-05-22 Biosensors International Group, Ltd. Automated coating apparatus and method
WO2009111033A2 (en) 2008-03-05 2009-09-11 Axela Inc. Detection of biomarkers and biomarker complexes
US20090233313A1 (en) * 2008-03-11 2009-09-17 Axela Inc. Quantification and affinity characterization of antibodies for the diagnosis of disease using optical diffraction
US9658221B2 (en) * 2008-08-28 2017-05-23 The Governing Council Of The University Of Toronto Methods and devices for detection of analytes using bloch surface wave-enhanced diffraction-based sensors
FR2935804B1 (fr) * 2008-09-11 2012-11-02 Innopsys Procede de recherche d'au moins un analyte dans un milieu susceptible de le contenir
WO2010063116A1 (en) * 2008-12-02 2010-06-10 National Research Council Of Canada Grating-based evanescent field molecular sensor using a thin silicon waveguide layer
JP5452140B2 (ja) * 2009-09-03 2014-03-26 日本航空電子工業株式会社 水素検出用表面プラズモン共鳴素子、表面プラズモン共鳴式光学水素検出器及び表面プラズモン共鳴を利用して光学的に水素を検出する方法
US8717172B2 (en) * 2009-09-09 2014-05-06 Absolute Software Corporation Alert for real-time risk of theft or loss
KR101105328B1 (ko) * 2009-11-23 2012-01-16 한국표준과학연구원 분자 흡착 및 해리 동특성 측정장치 및 측정방법
EP2773327A4 (de) 2011-11-02 2015-06-03 Univ California Neuprogrammierung von zelladhäsion
EP2741074A1 (de) * 2012-12-04 2014-06-11 F. Hoffmann-La Roche AG Vorrichtung zur Verwendung bei der Bindeaffinitätserkennung
CA2907105C (en) * 2013-03-18 2022-10-25 Smiths Detection Montreal Inc. Trace analyte collection swab
US10094762B2 (en) * 2013-05-30 2018-10-09 UNIVERSITé LAVAL Patterned capillary device and process for fabricating thereof
EP2827130A1 (de) * 2013-07-15 2015-01-21 F. Hoffmann-La Roche AG Vorrichtung zur Verwendung bei der Bindeaffinitätserkennung
DE102013112415A1 (de) 2013-11-12 2015-05-13 Ludwig-Maximilians-Universität München Vorrichtung und Verfahren zur Untersuchung eines oder mehrerer Phasenobjekte
WO2017006679A1 (ja) * 2015-07-07 2017-01-12 古野電気株式会社 測定用チップ、測定装置、および測定方法
EP3433601A4 (de) * 2016-05-11 2019-11-20 IPG Photonics Corporation Verfahren und system zur messung der morphologischen charakteristika von laserlasergeglühten polykristallinen siliciumschichten für flachbildschirme
WO2018106931A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
FR3067042B1 (fr) 2017-06-02 2021-07-30 Univ De Lille 1 Sciences Et Technologies Procede de detection optique
FR3067043B1 (fr) * 2017-06-02 2021-06-25 Univ De Lille 1 Sciences Et Technologies Procede de detection optique
WO2019166562A1 (en) * 2018-03-01 2019-09-06 F. Hoffmann-La Roche Ag Device for use in the detection of binding affinities
US20210270736A1 (en) 2018-07-18 2021-09-02 Dr. Johannes Heidenhain Gmbh Diffractive biosensor
US11366109B2 (en) * 2018-12-06 2022-06-21 Winmems Technologies Co., Ltd. Encoded microflakes

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US598608A (en) * 1898-02-08 Machine for surface-sizing wadding
US4608344A (en) * 1981-09-18 1986-08-26 Battelle Memorial Institute Method for the determination of species in solution with an optical wave-guide
US4571081A (en) 1982-09-07 1986-02-18 Coulter Electronics Of New England, Inc. Light scattering apparatus and method
CA1237645A (en) * 1982-12-21 1988-06-07 John H. Fisher Assay technique
US4537861A (en) 1983-02-03 1985-08-27 Elings Virgil B Apparatus and method for homogeneous immunoassay
US4537867A (en) * 1983-12-14 1985-08-27 Exxon Research And Engineering Co. Promoted iron-cobalt spinel catalyst for Fischer-Tropsch processes
USRE33581E (en) 1984-06-25 1991-04-30 Immunoassay using optical interference detection
US4647544A (en) 1984-06-25 1987-03-03 Nicoli David F Immunoassay using optical interference detection
DE3680999D1 (de) 1985-05-29 1991-09-26 Artificial Sensing Instr Asi A Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahlaenderungen in messubstanzen.
US5468606A (en) 1989-09-18 1995-11-21 Biostar, Inc. Devices for detection of an analyte based upon light interference
GB8618133D0 (en) 1986-07-24 1986-09-03 Pa Consulting Services Biosensors
US4876208A (en) * 1987-01-30 1989-10-24 Yellowstone Diagnostics Corporation Diffraction immunoassay apparatus and method
US5089387A (en) * 1988-07-07 1992-02-18 Adeza Biomedical Corporation Dna probe diffraction assay and reagents
US4989972A (en) 1989-05-01 1991-02-05 Hewlett-Packard Company Low reflectivity surface relief gratings for photodetectors
US5014709A (en) * 1989-06-13 1991-05-14 Biologic Systems Corp. Method and apparatus for high resolution holographic imaging of biological tissue
US5089389A (en) * 1989-08-25 1992-02-18 Eastman Kodak Company Buffered composition, coated article test device and a method for their use
DE69027077T2 (de) * 1989-09-08 1996-10-02 Hewlett Packard Co Herstellung einer Festphase, geeignet für spezifische Bindung chemischer Substanzen
US5541057A (en) 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
US5639671A (en) 1989-09-18 1997-06-17 Biostar, Inc. Methods for optimizing of an optical assay device
US5376556A (en) 1989-10-27 1994-12-27 Abbott Laboratories Surface-enhanced Raman spectroscopy immunoassay
NZ238159A (en) * 1990-05-17 1992-03-26 Adeza Biomedical Corp Reflective biograting for diffraction immunoassays
US5955377A (en) 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
US5550063A (en) 1991-02-11 1996-08-27 Biostar, Inc. Methods for production of an optical assay device
US5196350A (en) 1991-05-29 1993-03-23 Omnigene, Inc. Ligand assay using interference modulation
JPH07505297A (ja) * 1992-04-06 1995-06-15 アボツト・ラボラトリーズ 内面全反射を使用して核酸または被分析物質を検出する方法及び装置
US5494829A (en) 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5736410A (en) 1992-09-14 1998-04-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US5512131A (en) * 1993-10-04 1996-04-30 President And Fellows Of Harvard College Formation of microstamped patterns on surfaces and derivative articles
US5599688A (en) 1993-10-18 1997-02-04 Precision Instrument Design Device and method for circulating fluid over a membrane
GB9406142D0 (en) 1994-03-28 1994-05-18 British Tech Group A sensor
US5599668A (en) 1994-09-22 1997-02-04 Abbott Laboratories Light scattering optical waveguide method for detecting specific binding events
FI101829B (fi) * 1995-03-07 1998-08-31 Erkki Juhani Soini Biospesifinen määritysmenetelmä
US5922554A (en) * 1995-10-30 1999-07-13 The Regents Of The University Of California Inhibition of cellular uptake of cholesterol
US5837196A (en) 1996-01-26 1998-11-17 The Regents Of The University Of California High density array fabrication and readout method for a fiber optic biosensor
US6586193B2 (en) * 1996-04-25 2003-07-01 Genicon Sciences Corporation Analyte assay using particulate labels
US5922550A (en) 1996-12-18 1999-07-13 Kimberly-Clark Worldwide, Inc. Biosensing devices which produce diffraction images
US6180288B1 (en) * 1997-03-21 2001-01-30 Kimberly-Clark Worldwide, Inc. Gel sensors and method of use thereof
US5925878A (en) 1997-08-20 1999-07-20 Imation Corp. Diffraction anomaly sensor having grating coated with protective dielectric layer
JP3507319B2 (ja) * 1997-12-08 2004-03-15 キヤノン株式会社 光学的特性測定装置
US6060256A (en) 1997-12-16 2000-05-09 Kimberly-Clark Worldwide, Inc. Optical diffraction biosensor
US6719868B1 (en) * 1998-03-23 2004-04-13 President And Fellows Of Harvard College Methods for fabricating microfluidic structures
US5986762A (en) 1998-06-15 1999-11-16 Imation Corp. Optical sensor having optimized surface profile
US20020037593A1 (en) 1999-01-25 2002-03-28 Craighead Harold G. Diffraction-based cell detection using a micro-contact-printed antibody grating
US6951715B2 (en) 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7094595B2 (en) 2000-10-30 2006-08-22 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7142296B2 (en) 2000-10-30 2006-11-28 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions

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US8753872B2 (en) 2014-06-17
CA2403427C (en) 2013-04-30
AU2001242173A1 (en) 2001-10-03
JP2003528311A (ja) 2003-09-24
WO2001071322A2 (en) 2001-09-27
JP4999249B2 (ja) 2012-08-15
EP1266207A2 (de) 2002-12-18
US7008794B2 (en) 2006-03-07
WO2001071322A3 (en) 2002-02-28
US20020025534A1 (en) 2002-02-28
EP1266207B1 (de) 2010-10-27
US20060099649A1 (en) 2006-05-11
CA2403427A1 (en) 2001-09-27
ATE486275T1 (de) 2010-11-15

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